Sartorius SARTOFLOW Advanced

    Equipment/facility: Equipment

      Description

      The SARTOFLOW® Advanced is a modular benchtop Crossflow system optimized for ultrafiltration, microfiltration and diafiltration applications used in many downstream processes, such as purification of

      -vaccines
      -monoclonal antibodies and
      -recombinant proteins

      The system is suitable for flexible use in laboratory environments for process development and clinical trials as well as for small-scale production batches.

      The SARTOFLOW® Advanced can be configured to accept either Sartocon® Slice or full-sized Sartocon® cassettes. As a result, this gives you an exceptionally wide range of membrane surface areas.

      Since all Sartocon® Crossflow cassettes have the same hydrodynamic flow path length, the SARTOFLOW® Advanced can be linearly scaled up from 0.1 to 2.1 m2 of membrane area. Its unique compact design has an ultra-low loop volume of ~200 ml, making it possible to concentrate even small process batches.

      A cylindrical 10 l stainless steel tank with a conical base – with or without a sight glass for visual monitoring – and a double-jacket vessel for cooling, or a bag stand for 5l, 10l or 20l single-use crossflow bags, are available as recirculation modules.

      This Crossflow system is equipped with our proven DCU-4 control unit that readily communicates with Sartorius´ BioPAT® SCADA, MFCS software

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      Steel tanks
      Membranes
      Monoclonal antibodies
      Microfiltration
      Vaccines
      Ultrafiltration
      Purification
      Stainless steel
      Hydrodynamics
      Cooling
      Glass
      Monitoring