Waters Q-TOF Premier

    Equipment/facility: Equipment

      Description

      Quadrupole Time-of-Flight (TOF) tandem mass spectrometer coupled to a quaternary HPLC system

      Uses
      Capable of a variety of ionization options that can apply to a range of compound classes, from small organic molecules to intact proteins of 60kD or more
      Quaternary HPLC allows for isocratic or gradient elution for chromatographic separations

      Details
      Delivers high sensitivity, resolution, and exact mass measurements for LC/MS applications.
      High resolution gives the selectivity needed to separate analyte spectra from interferences and background chemical noise.
      High sensitivity helps to achieve very low detection limits.
      Exact mass measurements of small molecules give the elemental composition information that can be used to identify these analytes.

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      Molecules
      Water
      Mass spectrometers
      Ionization
      Chemical analysis
      Proteins