X-Ray Crystallography Facility

    Equipment/facility: Facility

    • Location

      X-Ray Crystallography Facility Huck Institutes of the Life Sciences Penn State University 8 Althouse Lab University Park, PA 16802

      United States

    Description

    X-ray crystallography is the chief method for determining the atomic resolution three-dimensional structures of biological macromolecules. The focus of the facility is to provide the necessary infrastructure and support for individual investigators to undertake single crystal X-ray structural studies. We provide instrumentation, training and collaboration for:
    Protein characterization including dynamic light scattering, differential scanning calorimetry, bio-layer interferometry and circular dichroism
    Binding studies using isothermal titration calorimetry

    Robotic crystallization, incubators, UV and digital microscopes
    Robotic imaging
    Diffraction data collection and processing
    Structure determination and analysis
    Molecular modeling
    Small angle X-ray scattering


    Our experienced staff are available to train researchers to use equipment and to assist project development and research.

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    X ray crystallography
    Dynamic light scattering
    Crystallization
    X ray scattering
    Macromolecules
    Titration
    Interferometry
    Differential scanning calorimetry
    Robotics
    Microscopes
    Single crystals
    X rays
    Proteins