Biochemistry & Molecular Biology

  • United States

Research Output 1961 2019

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Letter
2019
5 Citations (Scopus)

An N-nitrosating metalloenzyme constructs the pharmacophore of streptozotocin

Ng, T. L., Rohac, R., Mitchell, A. J., Boal, A. K. & Balskus, E. P., Feb 7 2019, In : Nature. 566, 7742, p. 94-99 6 p.

Research output: Contribution to journalLetter

Streptozocin
Iron
Synthetic Chemistry Techniques
Guanidine
Enzymes
2 Citations (Scopus)

Gut microbiota–bile acid–interleukin-22 axis orchestrates polycystic ovary syndrome

Qi, X., Yun, C., Sun, L., Xia, J., Wu, Q., Wang, Y., Wang, L., Zhang, Y., Liang, X., Wang, L., Gonzalez, F. J., Patterson, A. D., Liu, H., Mu, L., Zhou, Z., Zhao, Y., Li, R., Liu, P., Zhong, C., Pang, Y. & 2 others, Jiang, C. & Qiao, J., Aug 1 2019, In : Nature Medicine. 25, 8, p. 1225-1233 9 p.

Research output: Contribution to journalLetter

Polycystic Ovary Syndrome
Glycodeoxycholic Acid
Insulin
Bile Acids and Salts
Metabolism

Selection on Aedes aegypti alters Wolbachia-mediated dengue virus blocking and fitness

Ford, S. A., Allen, S. L., Ohm, J. R., Sigle, L. T., Sebastian, A., Albert, I., Chenoweth, S. F. & McGraw, E. A., Jan 1 2019, (Accepted/In press) In : Nature Microbiology.

Research output: Contribution to journalLetter

Wolbachia
Dengue Virus
Aedes
Culicidae
Dengue
2017
9 Citations (Scopus)

Celebrating parasites

Greene, C. S., Garmire, L. X., Gilbert, J. A., Ritchie, M. D. & Hunter, L. E., Mar 30 2017, In : Nature Genetics. 49, 4, p. 483-484 2 p.

Research output: Contribution to journalLetter

Parasites
3 Citations (Scopus)

Correspondence: DNA shape is insufficient to explain binding

Rossi, M., Lai, W. & Pugh, B. F., Jun 5 2017, In : Nature Communications. 8, 15643.

Research output: Contribution to journalLetter

Biophysical Phenomena
Telomere-Binding Proteins
Fungal Genome
Fungal DNA
Saccharomyces cerevisiae Proteins
Open Access
Chromatography
Alcohols
Blood
Uncertainty
2016
1 Citation (Scopus)

A need for precision medicine to enable tailored special education

Polyak, A. & Girirajan, S., Mar 1 2016, In : American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 171, 2, p. 300 1 p.

Research output: Contribution to journalLetter

Special Education
Precision Medicine
Autistic Disorder
2015
48 Citations (Scopus)

Multi-omic data analysis using Galaxy

Boekel, J., Chilton, J. M., Cooke, I. R., Horvatovich, P. L., Jagtap, P. D., Käll, L., Lehtiö, J., Lukasse, P., Moerland, P. D. & Griffin, T. J., Jan 1 2015, In : Nature Biotechnology. 33, 2, p. 137-139 3 p.

Research output: Contribution to journalLetter

Galaxies
Proteomics
2014
76 Citations (Scopus)

Dissemination of scientific software with Galaxy ToolShed

Blankenberg, D. J., Von Kuster, G., Bouvier, E., Baker, D., Afgan, E., Stoler, N., Taylor, J., Nekrutenko, A., Clements, D., Coraor, N., Eberhard, C., Francheteau, D., Goecks, J., Guerler, S., Jackson, J. L., Cooke, I., Johnson, J., Kirton, E., Cock, P., Chapman, B. & 2 others, Grüning, B. & Lazarus, R., Feb 20 2014, In : Genome biology. 15, 2, 403.

Research output: Contribution to journalLetter

Galaxies
Software
software
freedom
analysis
1 Citation (Scopus)

Forensic DNA applications: An interdisciplinary perspective - A new book in forensic science

Primorac, D. & Schanfield, M., Jan 1 2014, In : Croatian Medical Journal. 55, 4, p. 434-436 3 p.

Research output: Contribution to journalLetter

Forensic Sciences
DNA
21 Citations (Scopus)

Four previously identified petunia inflata s-locus f-box genes are involved in pollen specificity in self-incompatibility

Williams, J. S., Natale, C. A., Wang, N., Li, S., Brubaker, T. R., Sun, P. & Kao, T., Jan 1 2014, In : Molecular plant. 7, 3, p. 567-569 3 p.

Research output: Contribution to journalLetter

4 Citations (Scopus)

Reply to Brunet and Doolittle: Both selected effect and causal role elements can influence human biology and disease

Kellis, M., Wold, B., Snyder, M. P., Bernstein, B. E., Kundaje, A., Marinov, G. K., Ward, L. D., Birney, E., Crawford, G. E., Dekker, J., Dunham, I., Elnitski, L. L., Farnham, P. J., Feingold, E. A., Gerstein, M., Giddings, M. C., Gilbert, D. M., Gingeras, T. R., Green, E. D., Guigo, R. & 10 others, Hubbard, T., Kent, J., Lieb, J. D., Myers, R. M., Pazin, M. J., Ren, B., Stamatoyannopoulos, J., Weng, Z., White, K. P. & Hardison, R. C., Aug 19 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 33

Research output: Contribution to journalLetter

2012
23 Citations (Scopus)

A cautionary note on switching mitochondrial DNA reference sequences in forensic genetics

Salas, A., Coble, M., Desmyter, S., Grzybowski, T., Gusmão, L., Hohoff, C., Holland, M. M., Irwin, J. A., Kupiec, T., Lee, H. Y., Ludes, B., Lutz-Bonengel, S., Melton, T., Parsons, T. J., Pfeiffer, H., Prieto, L., Tagliabracci, A. & Parson, W., Dec 1 2012, In : Forensic Science International: Genetics. 6, 6

Research output: Contribution to journalLetter

Forensic Genetics
Phylogeography
Mitochondrial DNA
DNA Sequence Analysis
Haplotypes
259 Citations (Scopus)

An encyclopedia of mouse DNA elements (Mouse ENCODE)

Stamatoyannopoulos, J. A., Snyder, M., Hardison, R. C., Ren, B., Gingeras, T., Gilbert, D. M., Groudine, M., Bender, M., Kaul, R., Canfield, T., Giste, E., Johnson, A., Zhang, M., Balasundaram, G., Byron, R., Roach, V., Sabo, P. J., Sandstrom, R., Stehling, A. S., Thurman, R. E. & 66 others, Weissman, S. M., Cayting, P., Hariharan, M., Lian, J., Cheng, Y., Landt, S. G., Ma, Z., Wold, B. J., Dekker, J., Crawford, G. E., Keller Capone, C. A., Wu, W., Morrissey, C., Kumar, S. A., Mishra, T., Jain, D., Byrska-Bishop, M., Blankenberg, D. J., Lajoiel, B. R., Jain, G., Sanyal, A., Chen, K. B., Denas, O., Taylor, J., Blobel, G. A., Weiss, M. J., Pimkin, M., Deng, W., Marinov, G. K., Williams, B. A., Fisher-Aylor, K. I., Desalvo, G., Kiralusha, A., Trout, D., Amrhein, H., Mortazavi, A., Edsall, L., McCleary, D., Kuan, S., Shen, Y., Yue, F., Ye, Z., Davis, C. A., Zaleski, C., Jha, S., Xue, C., Dobin, A., Lin, W., Fastuca, M., Wang, H., Guigo, R., Djebali, S., Lagarde, J., Ryba, T., Sasaki, T., Malladi, V. S., Cline, M. S., Kirkup, V. M., Learned, K., Rosenbloom, K. R., Kent, W. J., Feingold, E. A., Good, P. J., Pazin, M., Lowdon, R. F. & Adams, L. B., Aug 13 2012, In : Genome biology. 13, 8, 418.

Research output: Contribution to journalLetter

Encyclopedias
DNA
mice
Genomics
genomics

Comment on emerging functions of transcription factors in malaria parasite

Painter Ponton, H. J. & Llinas, M., Jun 20 2012, In : Journal of Biomedicine and Biotechnology. 2012, 754054.

Research output: Contribution to journalLetter

Gene Expression Regulation
Plasmodium falciparum
Malaria
Parasites
Transcription Factors
24 Citations (Scopus)

NGS analyses by visualization with Trackster

Goecks, J., Coraor, N., Nekrutenko, A. & Taylor, J., Nov 1 2012, In : Nature Biotechnology. 30, 11, p. 1036-1039 4 p.

Research output: Contribution to journalLetter

User-Computer Interface
Computer Graphics
Genetic Databases
Data Mining
Chromosome Mapping
2011
81 Citations (Scopus)

Harnessing cloud computing with Galaxy Cloud

Afgan, E., Baker, D., Coraor, N., Goto, H., Paul, I., Makova, K. D., Nekrutenko, A. & Taylor, J., Nov 1 2011, In : Nature Biotechnology. 29, 11, p. 972-974 3 p.

Research output: Contribution to journalLetter

Galaxies
Cloud computing
Mitochondrial DNA
Internet
2010
30 Citations (Scopus)

A preoccupied position on nucleosomes

Pugh, B. F., Aug 1 2010, In : Nature Structural and Molecular Biology. 17, 8, 1 p.

Research output: Contribution to journalLetter

Chromatin Assembly and Disassembly
Nucleosomes
Histones
Saccharomyces cerevisiae
2009

Response to "An assessment of the human health risks from exposure to polybrominated diphenyl ethers (PBDEs) in house dust" by Marek Banasik et al.

Sjödin, A., Päpke, O., McGahee, E., Focant, J. F., Jones, R. S., Pless-Mulloli, T., Toms, L. M. L., Herrmann, T., Müller, J., Needham, L. L. & Patterson, D. G. J., Oct 1 2009, In : Chemosphere. 77, 5, p. 706-707 2 p.

Research output: Contribution to journalLetter

Halogenated Diphenyl Ethers
Health risks
Dust
Ethers
Health
2008
20 Citations (Scopus)

The validity of mitochondrial dehydrogenases as antimalarial drug targets

Vaidya, A. B., Painter Ponton, H. J., Morrisey, J. M. & Mather, M. W., Jan 1 2008, In : Trends in Parasitology. 24, 1, p. 8-9 2 p.

Research output: Contribution to journalLetter

Plasmodium
Antimalarials
Drug Delivery Systems
Malaria
Mitochondria
2007
12 Citations (Scopus)

Genetic heterogeneity is not as threatening as you might think

Ritchie, M. D., Edwards, T. L., Fanelli, T. J. & Motsinger, A. A., Nov 1 2007, In : Genetic Epidemiology. 31, 7, p. 797-800 4 p.

Research output: Contribution to journalLetter

Genetic Heterogeneity
Quantitative Trait Loci
Genetic Models
20 Citations (Scopus)

Problems with genome-wide association studies [3]

Williams, S. M., Canter, J. A., Crawford, D. C., Moore, J. H., Ritchie, M. D. & Haines, J. L., Jun 29 2007, In : Science. 316, 5833, p. 1841-1842 2 p.

Research output: Contribution to journalLetter

2006
3 Citations (Scopus)
forensic medicine
casework
2005

Croatian minister rejects 'meddling' claim [1]

Primorac, D., Jan 20 2005, In : Nature. 433, 7023, 1 p.

Research output: Contribution to journalLetter

Clergy

No evidence for Croatian race claims [2]

Primorac, D., Oct 6 2005, In : Nature. 437, 7060, 1 p.

Research output: Contribution to journalLetter

science in general
2004
11 Citations (Scopus)

Ongoing controversy over Romanov remains [1] (multiple letters)

Hofreiter, M., Loreille, O., Ferriola, D., Parsons, T. J., Gill, P., Hagelberg, E., Knight, A., Zhivotovsky, L. A., Kass, D. H., Litwin, D. E., Green, L. D. & White, P. S., Oct 15 2004, In : Science. 306, 5695, p. 407-410 4 p.

Research output: Contribution to journalLetter

20th Century History
Famous Persons
Tissue Preservation
Forensic Anthropology
Bayes Theorem
2001
73 Citations (Scopus)

Dioxygen reactivity of mononuclear heme and copper components yielding a high-spin heme-peroxo-Cu complex [3]

Ghiladi, R. A., Hatwell, K. R., Karlin, K. D., Huang, H. W., Moënne-Loccoz, P., Krebs, C., Huynh, B. H., Marzilli, L. A., Cotter, R. J., Kaderli, S. & Zuberbühler, A. D., Oct 3 2001, In : Journal of the American Chemical Society. 123, 25, p. 6183-6184 2 p.

Research output: Contribution to journalLetter

Ferric Compounds
Organometallic Compounds
Magnetic resonance spectroscopy
Molecular Conformation
Molecular Models
45 Citations (Scopus)

Proton inventory of the genomic HDV ribozyme in Mg2+-containing solutions [3]

Nakano, S. I. & Bevilacqua, P. C., Nov 14 2001, In : Journal of the American Chemical Society. 123, 45, p. 11333-11334 2 p.

Research output: Contribution to journalLetter

Catalytic RNA
Deuterium
Divalent Cations
Magnesium
Protons
2000
2 Citations (Scopus)

Commentary on the American Board of Criminalistics (ABC) Certification Process [3]

Adamo, R., Chany, C., Drummond, F., Hung, S. M., Pool, T., Quarino, L., Ristenbatt, R. R., San Pietro, D. & Selavka, C. M., 2000, In : Journal of Forensic Sciences. 45, 3, p. 749-750 2 p.

Research output: Contribution to journalLetter

Professional Competence
Laboratory Personnel
forensic medicine
Forensic Medicine
Certification
89 Citations (Scopus)
Polyelectrolytes
Adsorption
Water
Liquids
65 Citations (Scopus)

Valence-delocalized diiron(II,III) cores supported by carboxylate-only bridging ligands [11]

Lee, D., Krebs, C., Huynh, B. H., Hendrich, M. P. & Lippard, S. J., May 24 2000, In : Journal of the American Chemical Society. 122, 20, p. 5000-5001 2 p.

Research output: Contribution to journalLetter

Ligands
1999
77 Citations (Scopus)
Phospholipids
Membranes
Fluids
86 Citations (Scopus)

Formation of Fe(III)Fe(IV) species from the reaction between a diiron(II) complex and dioxygen: Relevance to ribonucleotide reductase intermediate X [12]

Lee, D., Du Bois, J., Petasis, D., Hendrich, M. P., Krebs, C., Huynh, B. H. & Lippard, S. J., Oct 27 1999, In : Journal of the American Chemical Society. 121, 42, p. 9893-9894 2 p.

Research output: Contribution to journalLetter

Ribonucleotide Reductases
Oxygen
Oxidoreductases
1998
26 Citations (Scopus)

Are the hypervariable regions of S RNases sufficient for allele-specific recognition of pollen? (multiple letters)

Verica, J. A., McCubbin, A. G., Kao, T., Matton, D. P., Morse, D. & Cappadocia, M., Jan 1 1998, In : Plant Cell. 10, 3, p. 314-316 3 p.

Research output: Contribution to journalLetter

ribonuclease S
120 Citations (Scopus)
methane monooxygenase
Ribonucleotide Reductases
Escherichia coli
Methane
Proteins
53 Citations (Scopus)

Generation of a mixed-valent Fe(III)Fe(IV) form of intermediate Q in the reaction cycle of soluble methane monooxygenase, an analog of intermediate X in ribonucleotide reductase R2 assembly [10]

Valentine, A. M., Tavares, P., Pereira, A. S., Davydov, R., Krebs, C., Hoffman, B. M., Edmondson, D. E., Boi Hanh Huynh, H. H. & Lippard, S. J., Mar 11 1998, In : Journal of the American Chemical Society. 120, 9, p. 2190-2191 2 p.

Research output: Contribution to journalLetter

methane monooxygenase
Ribonucleotide Reductases
7 Citations (Scopus)

Molecular evolution of spectrin repeats

Thomas, C. M., Jul 1 1998, In : BioEssays. 20, 7, 1 p.

Research output: Contribution to journalLetter

spectrin
Spectrin
Molecular Evolution
Nucleic Acid Repetitive Sequences
Genetic Models
1997
229 Citations (Scopus)

What keeps sandcastles standing? [4]

Hornbaker, D. J., Albert, R. Z., Albert, I., Barabasi, A. L. & Schiffer, P., Jan 1 1997, In : Nature. 387, 6635, 1 p.

Research output: Contribution to journalLetter

1996
222 Citations (Scopus)

Change in sex ratio with exposure to dioxin [14]

Mocarelli, P., Brambilla, P., Gerthoux, M. P., Patterson, D. G. J. & Needham, L. L., Jan 1 1996, In : Lancet. 348, 9024, 1 p.

Research output: Contribution to journalLetter

Dioxins
Sex Ratio
1990
8 Citations (Scopus)

Bacitracin-associated peptides and contaminated L-tryptophan

Barnhart, E. R., Maggio, V. L., Alexander, L. R., Turner, W. E., Patterson, D. G., Needham, L. L., Reilly, M. H. & Gelbaum, L. T., Sep 22 1990, In : The Lancet. 336, 8717, 1 p.

Research output: Contribution to journalLetter

1988

Cover blown [10]

Lesk, A. & Lesk, V. I., Jan 1 1988, In : Nature. 334, 6183, 1 p.

Research output: Contribution to journalLetter

1984

IgA release using phorbol?

Mastro, A. M., Jul 1 1984, In : Journal of Immunology. 133, 1, 1 p.

Research output: Contribution to journalLetter

Phorbols
Tetradecanoylphorbol Acetate
Immunoglobulin A
phorbol
1980
10 Citations (Scopus)

On the Gibbs paradox: What does indistinguishability really mean?

Lesk, A., Apr 1 1980, In : Journal of Physics A: Mathematical and General. 13, 4, p. L111-L114

Research output: Contribution to journalLetter

paradoxes
Paradox
Entropy
entropy
Gases
4 Citations (Scopus)

Reinterpretation of Moseley’s experiments relating K α line frequencies and atomic number

Lesk, A., 1980, In : American Journal of Physics. 48, 6, p. 492-493 2 p.

Research output: Contribution to journalLetter

1976
1 Citation (Scopus)

Treatment of nonspecular reflection in the single•particle model of an ideal gas

Lesk, A., Jan 1 1976, In : American Journal of Physics. 44, 11, p. 1134-1135 2 p.

Research output: Contribution to journalLetter

ideal gas
1973
4 Citations (Scopus)

On hypothesized selective pressure by u.v. on DNA base compositions

Lesk, A., Jan 1 1973, In : Journal of Theoretical Biology. 40, 1, p. 201-202 2 p.

Research output: Contribution to journalLetter

Thymine
Radiation effects
Asparagine
Adenine
Phenylalanine
1970
4 Citations (Scopus)
Genetic Code
genetic code
Nucleic acids
Nucleic Acids
nucleic acids
1969
5 Citations (Scopus)

Why does DNA contain thymine and RNA uracil?

Lesk, A., Jan 1 1969, In : Journal of Theoretical Biology. 22, 3, p. 537-540 4 p.

Research output: Contribution to journalLetter

Radiation Genetics
thymine
uracil
Thymine
Uracil
1968

Transfer experiments: A plea for tolerance [4]

Lesk, A., 1968, In : Science. 159, 3818, p. 921-923 3 p.

Research output: Contribution to journalLetter