• United States

Research Output

2020

The primary mechanism of cytotoxicity of the chemotherapeutic agent CX-5461 is topoisomerase II poisoning

Bruno, P. M., Lu, M., Dennis, K. A., Inam, H., Moore, C. J., Sheehe, J., Elledge, S. J., Hemann, M. T. & Pritchard, J. R., Feb 25 2020, In : Proceedings of the National Academy of Sciences of the United States of America. 117, 8, p. 4053-4060 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

Thermoacoustic combined tomography of abusive head trauma

Fadden, C., Thamburaj, K., Dias, M. & Kothapalli, S. R., Jan 1 2020, Medical Imaging 2020: Ultrasonic Imaging and Tomography. Byram, B. C. & Ruiter, N. V. (eds.). SPIE, 1131903. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 11319).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Thermo-responsive fluorescent nanoparticles for multimodal imaging and treatment of cancers

Pandey, N., Menon, J. U., Takahashi, M., Hsieh, J. T., Yang, J., Nguyen, K. T. & Wadajkar, A. S., Jan 1 2020, In : Nanotheranostics. 4, 1, p. 1-13 13 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Three-Dimensional Microtumors for Probing Heterogeneity of Invasive Bladder Cancer

Torab, P., Yan, Y., Yamashita, H., Warrick, J. I., Warrick, J. I., Raman, J. D., Degraff, D. J., Degraff, D. J., Degraff, D. J., Wong, P. K., Wong, P. K. & Wong, P. K., 2020, (Accepted/In press) In : Analytical chemistry.

Research output: Contribution to journalArticle

Towards a Low-Cost and Portable Photoacoustic Microscope for Point-of-Care and Wearable Applications

Dangi, A., Agrawal, S., Datta, G. R., Srinivasan, V. & Kothapalli, S. R., Jul 1 2020, In : IEEE Sensors Journal. 20, 13, p. 6881-6888 8 p., 8801865.

Research output: Contribution to journalArticle

Trends and advancements in shoulder biomechanics research

Morrow, M. M., Cutti, A. G. & Vidt, M. E., Jan 1 2020, (Accepted/In press) In : Journal of Electromyography and Kinesiology. 102409.

Research output: Contribution to journalArticle

Ultra-accurate Duplex Sequencing for the assessment of pretreatment ABL1 kinase domain mutations in Ph+ ALL

Short, N. J., Kantarjian, H., Kanagal-Shamanna, R., Sasaki, K., Ravandi, F., Cortes, J., Konopleva, M., Issa, G. C., Kornblau, S. M., Garcia-Manero, G., Garris, R., Higgins, J., Pratt, G., Williams, L. N., Valentine, C. C., Rivera, V. M., Pritchard, J., Salk, J. J., Radich, J. & Jabbour, E., May 1 2020, In : Blood Cancer Journal. 10, 5, 61.

Research output: Contribution to journalArticle

Open Access

Ultrasound-Guided Cytosolic Protein Delivery via Transient Fluorous Masks

Sloand, J. N., Nguyen, T. T., Zinck, S. A., Cook, E. C., Zimudzi, T., Showalter, S. A., Glick, A. B., Simon, J. & Medina, S. H., Apr 28 2020, In : ACS nano. 14, 4, p. 4061-4073 13 p.

Research output: Contribution to journalArticle

Unsupervised deep learning approach for photoacoustic spectral unmixing

Durairaj, D. A., Agrawal, S., Johnstonbaugh, K., Chen, H., Karri, S. P. K. & Kothapalli, S. R., 2020, Photons Plus Ultrasound: Imaging and Sensing 2020. Oraevsky, A. A. & Wang, L. V. (eds.). SPIE, 112403H. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 11240).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Welcome to the 16th International Conference on Pediatric Mechanical Circulatory Support Systems and Pediatric Cardiopulmonary Perfusion

Thangappan, K., Barnes, A., Lorts, A., Morales, D. L. S. & Ündar, A., Apr 1 2020, In : Artificial organs. 44, 4, p. 355-360 6 p.

Research output: Contribution to journalEditorial

2019

A Comprehensive Study of Ultrasound Transducer Characteristics in Microscopic Ultrasound Neuromodulation

Gougheri, H. S., Dangi, A., Kothapalli, S. R. & Kiani, M., Oct 2019, In : IEEE Transactions on Biomedical Circuits and Systems. 13, 5, p. 835-847 13 p., 8734697.

Research output: Contribution to journalArticle

1 Scopus citations

Adaptable microfluidic system for single-cell pathogen classification and antimicrobial susceptibility testing

Li, H., Torab, P., Mach, K. E., Surrette, C., England, M. R., Craft, D. W., Thomas, N. J., Liao, J. C., Puleo, C. & Wong, P. K., Jan 1 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 21, p. 10270-10279 10 p.

Research output: Contribution to journalArticle

8 Scopus citations

Age-Related Reduction in Cortical Thickness in First-Episode Treatment-Naïve Patients with Schizophrenia

Lin, Y., Li, M., Zhou, Y., Deng, W., Ma, X., Wang, Q., Guo, W., Li, Y., Jiang, L., Hu, X., Zhang, N. & Li, T., Aug 1 2019, In : Neuroscience Bulletin. 35, 4, p. 688-696 9 p.

Research output: Contribution to journalArticle

4 Scopus citations

All-night functional magnetic resonance imaging sleep studies

Moehlman, T. M., de Zwart, J. A., Chappel-Farley, M. G., Liu, X., McClain, I. B., Chang, C., Mandelkow, H., Özbay, P. S., Johnson, N. L., Bieber, R. E., Fernandez, K. A., King, K. A., Zalewski, C. K., Brewer, C. C., van Gelderen, P., Duyn, J. H. & Picchioni, D., Mar 15 2019, In : Journal of Neuroscience Methods. 316, p. 83-98 16 p.

Research output: Contribution to journalArticle

3 Scopus citations

A Multiwell Microfluidic Device for Analyzing and Screening Nonhormonal Contraceptive Agents

Li, H., Garner, T., Diaz, F. & Wong, P. K., Jul 12 2019, In : Small. 15, 28, 1901910.

Research output: Contribution to journalArticle

Aptamer-Functionalized Fibrin Hydrogel Improves Vascular Endothelial Growth Factor Release Kinetics and Enhances Angiogenesis and Osteogenesis in Critically Sized Cranial Defects

Juhl, O., Zhao, N., Merife, A. B., Cohen, D., Friedman, M., Zhang, Y., Schwartz, Z., Wang, Y. & Donahue, H., Nov 11 2019, In : ACS Biomaterials Science and Engineering. 5, 11, p. 6152-6160 9 p.

Research output: Contribution to journalArticle

A role for the claustrum in salience processing?

Smith, J. B., Watson, G. D. R., Liang, Z., Liu, Y., Zhang, N. & Alloway, K. D., Jun 3 2019, In : Frontiers in Neuroanatomy. 13, 64.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Arousal Contributions to Resting-State fMRI Connectivity and Dynamics

Gu, Y., Han, F. & Liu, X., Nov 5 2019, In : Frontiers in Neuroscience. 13, 1190.

Research output: Contribution to journalArticle

Open Access

Assembly of Bifunctional Aptamer-Fibrinogen Macromer for VEGF Delivery and Skin Wound Healing

Zhao, N., Coyne, J., Xu, M., Zhang, X., Suzuki, A., Shi, P., Lai, J., Fong, G. H., Xiong, N. & Wang, Y., Feb 12 2019, In : Chemistry of Materials. 31, 3, p. 1006-1015 10 p.

Research output: Contribution to journalArticle

8 Scopus citations

Beyond Purple Hearts: A Colorful Approach to Isolate Distinct Heart Cells from Human iPSCs

Randolph, L. N. & Lian, X. L., May 2 2019, In : Cell Stem Cell. 24, 5, p. 675-677 3 p.

Research output: Contribution to journalShort survey

Biomaterial-Based Metabolic Regulation in Regenerative Engineering

Ma, C., Kuzma, M. L., Bai, X. & Yang, J., Oct 1 2019, In : Advanced Science. 6, 19, 1900819.

Research output: Contribution to journalReview article

Open Access
2 Scopus citations

Bioresponsive peptide-polysaccharide nanogels — A versatile delivery system to augment the utility of bioactive cargo

Simonson, A. W., Lawanprasert, A., Goralski, T. D. P., Keiler, K. C. & Medina, S. H., Apr 2019, In : Nanomedicine: Nanotechnology, Biology, and Medicine. 17, p. 391-400 10 p.

Research output: Contribution to journalArticle

1 Scopus citations
7 Scopus citations
3 Scopus citations

Cellular Based Strategies for Microvascular Engineering

Koduru, S. V., Leberfinger, A. N., Pasic, D., Forghani, A., Lince, S., Hayes, D. J., Ozbolat, I. T. & Ravnic, D. J., Apr 15 2019, In : Stem Cell Reviews and Reports. 15, 2, p. 218-240 23 p.

Research output: Contribution to journalReview article

5 Scopus citations

Characterization of Photoluminescent Polylactone-Based Nanoparticles for Their Applications in Cardiovascular Diseases

Kuriakose, A. E., Pandey, N., Shan, D., Banerjee, S., Yang, J. & Nguyen, K. T., Nov 22 2019, In : Frontiers in Bioengineering and Biotechnology. 7, 353.

Research output: Contribution to journalArticle

Open Access

Chondrocyte mTORC1 activation stimulates miR-483-5p via HDAC4 in osteoarthritis progression

Wang, H., Zhang, H., Sun, Q., Yang, J., Zeng, C., Ding, C., Cai, D., Liu, A. & Bai, X., Mar 2019, In : Journal of Cellular Physiology. 234, 3, p. 2730-2740 11 p.

Research output: Contribution to journalArticle

5 Scopus citations

Chronic In Vivo Test of a Right Heart Replacement Blood Pump for Failed Fontan Circulation

Cysyk, J., Clark, J. B., Newswanger, R., Jhun, C. S., Izer, J., Finicle, H., Reibson, J., Doxtater, B., Weiss, W. & Rosenberg, G., Aug 1 2019, In : ASAIO Journal. 65, 6, p. 593-600 8 p.

Research output: Contribution to journalArticle

3 Scopus citations

Chronic ovine studies demonstrate low thromboembolic risk in the Penn State infant ventricular assist device

Lukic, B., Brian Clark, J., Izer, J. M., Cooper, T. K., Finicle, H. A., Cysyk, J., Doxtater, B., Yeager, E., Reibson, J., Newswanger, R. K., Leibich, P., Bletcher, K. & Weiss, W. J., 2019, In : ASAIO Journal. 65, 4, p. 371-379 9 p.

Research output: Contribution to journalArticle

1 Scopus citations

Collagen-infilled 3D printed scaffolds loaded with miR-148b-transfected bone marrow stem cells improve calvarial bone regeneration in rats

Moncal, K. K., Aydin, R. S. T., Abu-Laban, M., Heo, D. N., Rizk, E., Tucker, S. M., Lewis, G. S., Hayes, D. & Ozbolat, I. T., Dec 2019, In : Materials Science and Engineering C. 105, 110128.

Research output: Contribution to journalArticle

3 Scopus citations

Collective Cell Migration in 3D Epithelial Wound Healing

Xiao, Y., Riahi, R., Torab, P., Zhang, D. D. & Wong, P. K., Jan 1 2019, In : ACS nano.

Research output: Contribution to journalArticle

Combinatorial Delivery of miRNA-Nanoparticle Conjugates in Human Adipose Stem Cells for Amplified Osteogenesis

Abu-Laban, M., Hamal, P., Arrizabalaga, J. H., Forghani, A., Dikkumbura, A. S., Kumal, R. R., Haber, L. H. & Hayes, D. J., Dec 1 2019, In : Small. 15, 50, 1902864.

Research output: Contribution to journalArticle

Combined CD25, CD64, and CD69 biomarker panel for flow cytometry diagnosis of sepsis

Zhou, Y., Zhang, Y., Johnson, A., Venable, A., Griswold, J. & Pappas, D., Jan 1 2019, In : Talanta. 191, p. 216-221 6 p.

Research output: Contribution to journalArticle

5 Scopus citations

Computational translation of genomic responses from experimental model systems to humans

Brubaker, D. K., Proctor, E. A., Haigis, K. M. & Lauffenburger, D. A., 2019, In : PLoS computational biology. 15, 1, e1006286.

Research output: Contribution to journalArticle

4 Scopus citations

Computer assisted photoacoustic imaging guided device for safer percutaneous needle operations

Zhang, J., Agrawal, S., Dangi, A., Frings, N. & Kothapalli, S. R., Jan 1 2019, Photons Plus Ultrasound: Imaging and Sensing 2019. Oraevsky, A. A. & Wang, L. V. (eds.). SPIE, 1087866. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 10878).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

4 Scopus citations

Confinement and substrate topography control cell migration in a 3D computational model

Winkler, B., Aranson, I. S. & Ziebert, F., Dec 1 2019, In : Communications Physics. 2, 1, 82.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Correcting errors in the BRCA1 warning system

Liang, Y., Dearnaley, W. J., Alden, N. A., Solares, M. J., Gilmore, B. L., Pridham, K. J., Varano, C., Sheng, Z., Alli, E. & Kelly, D., Jan 2019, In : DNA Repair. 73, p. 120-128 9 p.

Research output: Contribution to journalArticle

Correction: Oncogenic KRAS confers chemoresistance by upregulating Nrf2 (Cancer Research (2014) 74 (7430-7441) DOI: 10.1158/0008-5472.CAN-14-1439)

Tao, S., Wang, S., Moghaddam, S. J., Ooi, A., Chapman, E., Wong, P. K. & Zhang, D. D., Mar 1 2019, In : Cancer Research. 79, 5, 1 p.

Research output: Contribution to journalComment/debate

Open Access

Cryo-EM-On-a-Chip: Custom-Designed Substrates for the 3D Analysis of Macromolecules

Alden, N. A., Varano, A. C., Dearnaley, W. J., Solares, M. J., Luqiu, W. Y., Liang, Y., Sheng, Z., McDonald, S. M., Damiano, J., McConnell, J., Dukes, M. J. & Kelly, D. F., May 24 2019, In : Small. 15, 21, 1900918.

Research output: Contribution to journalArticle

Cryo-EM Reveals Architectural Diversity in Active Rotavirus Particles

Hauser, M., Dearnaley, W. J., Varano, A. C., Casasanta, M., McDonald, S. M. & Kelly, D. F., 2019, In : Computational and Structural Biotechnology Journal. 17, p. 1178-1183 6 p.

Research output: Contribution to journalArticle

Open Access

Decellularized Adipose Tissue Hydrogel Promotes Bone Regeneration in Critical-Sized Mouse Femoral Defect Model

Mohiuddin, O. A., Campbell, B., Poche, J. N., Ma, M., Rogers, E., Gaupp, D., Harrison, M. A. A., Bunnell, B. A., Hayes, D. J. & Gimble, J. M., Sep 6 2019, In : Frontiers in Bioengineering and Biotechnology. 7, 211.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Decreasing Wound Edge Stress Enhances Leader Cell Formation during Collective Smooth Muscle Cell Migration

Dean, Z. S., Jamilpour, N., Slepian, M. J. & Wong, P. K., Aug 12 2019, In : ACS Biomaterials Science and Engineering. 5, 8, p. 3864-3875 12 p.

Research output: Contribution to journalArticle

2 Scopus citations

Detection of culture-negative sepsis in clinical blood samples using a microfluidic assay for combined CD64 and CD69 cell capture

Zhou, Y., Zhang, Y., Johnson, A., Venable, A., Griswold, J. & Pappas, D., Jul 25 2019, In : Analytica Chimica Acta. 1062, p. 110-117 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

Determination and pharmacokinetics and bioavailability of O-demethyl nuciferine in mice by UPLC–MS/MS

Wu, H., Lu, M., He, J., Huang, M., Zheng, A., Zhang, M., Wen, C. & Ye, J., 2019, In : Acta Chromatographica. 31, 3, p. 222-227 6 p.

Research output: Contribution to journalArticle

Open Access

Development of a Pain Scoring System for Use in Sheep Surgically Implanted with Ventricular Assist Devices

Izer, J. M., LaFleur, R. A., Weiss, W. J. & Wilson, R. P., Nov 17 2019, In : Journal of Investigative Surgery. 32, 8, p. 706-715 10 p.

Research output: Contribution to journalArticle

Development of osteopromotive poly (octamethylene citrate glycerophosphate) for enhanced bone regeneration

He, Y., Li, Q., Ma, C., Xie, D., Li, L., Zhao, Y., Shan, D., Chomos, S. K., Dong, C., Tierney, J. W., Sun, L., Lu, D., Gui, L. & Yang, J., Jul 15 2019, In : Acta Biomaterialia. 93, p. 180-191 12 p.

Research output: Contribution to journalArticle

3 Scopus citations

Direct observation of individual tubulin dimers binding to growing microtubules

Mickolajczyk, K. J., Geyer, E. A., Kim, T., Rice, L. M. & Hancock, W. O., Apr 9 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 15, p. 7314-7322 9 p.

Research output: Contribution to journalArticle

12 Scopus citations

DNA Transformer for Visualizing Endogenous RNA Dynamics in Live Cells

Wan, Y., Zhu, N., Lu, Y. & Wong, P. K., Feb 19 2019, In : Analytical chemistry. 91, 4, p. 2626-2633 8 p.

Research output: Contribution to journalArticle

4 Scopus citations

Dual aptamer-functionalized in situ injectable fibrin hydrogel for promotion of angiogenesis via co-delivery of growth factors

Zhao, N., Suzuki, A., Zhang, X. & Wang, Y., Jan 1 2019, Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting. Society for Biomaterials, 1 p. (Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium; vol. 40).

Research output: Chapter in Book/Report/Conference proceedingConference contribution