• United States

Research Output 1974 2020

Article
10 Citations (Scopus)

Hyperosmolality inhibits sodium absorption and chloride secretion in mIMCD-K2 cells

Green, R. B., Slattery, M. J., Gianferrari, E., Kizer, N. L., McCoy, D. E. & Stanton, B. A., Dec 1 1996, In : American Journal of Physiology. 271, 6 PART 2, p. F1248-F1254

Research output: Contribution to journalArticle

Arginine Vasopressin
Sodium Chloride
Osmolar Concentration
Cystic Fibrosis Transmembrane Conductance Regulator
Extracellular Fluid
2 Citations (Scopus)

Identification of a mechanogenetic link between substrate stiffness and chemotherapeutic response in breast cancer

Medina, S. H., Bush, B., Cam, M., Sevcik, E., DelRio, F. W., Nandy, K. & Schneider, J. P., May 2019, In : Biomaterials. 202, p. 1-11 11 p.

Research output: Contribution to journalArticle

Stiffness
Breast Neoplasms
Cells
Substrates
Cell culture
16 Citations (Scopus)

Identification of genes required for Mycobacterium abscessus growth in vivo with a prominent role of the ESX-4 locus

Laencina, L., Dubois, V., Le Moigne, V., Viljoen, A., Majlessi, L., Pritchard, J., Bernut, A., Piel, L., Roux, A. L., Gaillard, J. L., Lombard, B., Loew, D., Rubin, E. J., Brosch, R., Kremer, L., Herrmann, J. L. & Girard-Misguich, F., Jan 30 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 5, p. E1002-E1011

Research output: Contribution to journalArticle

Amoeba
Mycobacterium
Phagosomes
Growth
Genes
2 Citations (Scopus)
Small Interfering RNA
Cell Shape
Bone Regeneration
GTP Phosphohydrolases
Gene Silencing
20 Citations (Scopus)

Identification of neurotoxic cytokines by profiling Alzheimer's disease tissues and neuron culture viability screening

Wood, L. B., Winslow, A. R., Proctor, E. A., McGuone, D., Mordes, D. A., Frosch, M. P., Hyman, B. T., Lauffenburger, D. A. & Haigis, K. M., Nov 2015, In : Scientific reports. 5, 16622.

Research output: Contribution to journalArticle

Alzheimer Disease
Cytokines
Neurons
Vascular Endothelial Growth Factor A
Amyloid
27 Citations (Scopus)

Identification of the β1-integrin binding site on α-actinin by cryoelectron microscopy

Kelly, D. F. & Taylor, K. A., Mar 2005, In : Journal of Structural Biology. 149, 3, p. 290-302 13 p.

Research output: Contribution to journalArticle

Cryoelectron Microscopy
Actinin
Integrins
Binding Sites
Nickel
39 Citations (Scopus)

IL-4-induced Stat6 activities affect apoptosis and gene expression in breast cancer cells

Zhang, W. J., Li, B. H., Yang, X. Z., Li, P. D., Yuan, Q., Liu, X. H., Xu, S. B., Zhang, Y., Yuan, J., Gerhard, G. S., Masker, K. K., Dong, C., Koltun, W. A. & Chorney, M. J., Apr 1 2008, In : Cytokine. 42, 1, p. 39-47 9 p.

Research output: Contribution to journalArticle

Gene expression
Interleukin-4
Genes
Cells
Apoptosis
8 Citations (Scopus)

Image enhancement of the in vivo leukocyte-endothelium contact zone using optical sectioning microscopy

Shen, Z. & Lipowsky, H. H., Jan 1 1997, In : Annals of Biomedical Engineering. 25, 3, p. 521-535 15 p.

Research output: Contribution to journalArticle

Image enhancement
Optical microscopy
Endothelial cells
Blood
Cell adhesion
32 Citations (Scopus)

Imaging optically scattering objects with ultrasound-modulated optical tomography

Kothapalli, S. R., Sakadžić, S., Kim, C. & Wang, L. V., Aug 15 2007, In : Optics Letters. 32, 16, p. 2351-2353 3 p.

Research output: Contribution to journalArticle

scattering coefficients
tomography
image contrast
scattering
complement
22 Citations (Scopus)

Immune Cell-Mediated Biodegradable Theranostic Nanoparticles for Melanoma Targeting and Drug Delivery

Xie, Z., Su, Y., Kim, G. B., Selvi, E., Ma, C., Aragon-Sanabria, V., Hsieh, J. T., Dong, C. & Yang, J., Mar 14 2017, In : Small. 13, 10, 1603121.

Research output: Contribution to journalArticle

Drug Delivery Systems
Drug delivery
Nanoparticles
Melanoma
Macrophages
9 Citations (Scopus)

Immunoediting of leukocyte functions within the tumor microenvironment promotes cancer metastasis development

Dong, C. & Robertson, G. P., Sep 21 2009, In : Biorheology. 46, 4, p. 265-279 15 p.

Research output: Contribution to journalArticle

Tumor Microenvironment
Leukocytes
Melanoma
Neoplasm Metastasis
Neoplasms
19 Citations (Scopus)

Immunological identification of fibrinogen in dual-component protein films by AFM imaging

Soman, P., Rice, Z. & Siedlecki, C. A., Oct 1 2008, In : Micron. 39, 7, p. 832-842 11 p.

Research output: Contribution to journalArticle

fibrinogen
Atomic Force Microscopy
Fibrinogen
Atomic force microscopy
atomic force microscopy
5 Citations (Scopus)
Artificial heart
Pediatrics
1 Citation (Scopus)

Impact of cannula size and line length on venous line pressure in pediatric VA-/VV-ECLS circuits

Wang, S., Kunselman, A. R. & Ündar, A., Jan 1 2019, In : Artificial organs. 43, 8, p. E165-E177

Research output: Contribution to journalArticle

Pediatrics
Venous Pressure
Extracorporeal Membrane Oxygenation
Networks (circuits)
Tubing
12 Citations (Scopus)

Impact of design parameters on bileaflet mechanical heart valve flow dynamics

Govindarajan, V., Udaykumar, H. S., Herbertson, L. H., Deutsch, S., Manning, K. B. & Chandran, K. B., Sep 1 2009, In : Journal of Heart Valve Disease. 18, 5, p. 535-545 11 p.

Research output: Contribution to journalArticle

Heart Valves
Platelet Activation
Thrombosis
Heart Valve Prosthesis
Blood Platelets

Impact of Heart Rate on Pulsatile Hemodynamic Performance in a Neonatal ECG-Synchronized ECLS System

Wang, S., Moroi, M. K., Force, M., Kunselman, A. & Undar, A., Jan 1 2019, In : Artificial organs. 43, 1, p. 81-89 9 p.

Research output: Contribution to journalArticle

Hemodynamics
Pulsatile Flow
Pulsatile flow
Electrocardiography
Heart Rate
26 Citations (Scopus)

Impact of membrane oxygenators on pulsatile versus nonpulsatile perfusion in a neonatal model

Ündar, A., Koenig, K. M., Frazier, O. H. & Fraser, C. D., Jan 1 2000, In : Perfusion. 15, 2, p. 111-120 10 p.

Research output: Contribution to journalArticle

Oxygenators
Membrane Oxygenators
Perfusion
Membranes
Pressure
10 Citations (Scopus)
Oxygenators
Pulsatile Flow
Extracorporeal Membrane Oxygenation
Hemodynamics
Pressure drop
15 Citations (Scopus)
Life Support Systems
Pulsatile Flow
Pulsatile flow
Extracorporeal Membrane Oxygenation
Pediatrics
10 Citations (Scopus)
Life Support Systems
Pulsatile Flow
Extracorporeal Membrane Oxygenation
Hemodynamics
Pediatrics
17 Citations (Scopus)

Impact of Pulsatile Perfusion on Clinical Outcomes of Neonates and Infants With Complex Pathologies Undergoing Cardiopulmonary Bypass Procedures

Alkan-Bozkaya, T., Akçevin, A., Türkoǧlu, H. & Undar, A., Jan 1 2013, In : Artificial organs. 37, 1, p. 82-86 5 p.

Research output: Contribution to journalArticle

Pulsatile Flow
Pathology
Cardiopulmonary Bypass
Transposition of Great Vessels
Pediatrics
17 Citations (Scopus)

Impact of Pulsatility and Flow Rates on Hemodynamic Energy Transmission in an Adult Extracorporeal Life Support System

Wolfe, R., Strother, A., Wang, S., Kunselman, A. R. & Ündar, A., Jul 1 2015, In : Artificial organs. 39, 7, p. E127-E137

Research output: Contribution to journalArticle

Life Support Systems
Extracorporeal Membrane Oxygenation
Hemodynamics
Flow rate
Pulsatile Flow
7 Citations (Scopus)

Impact of the postpump resistance on pressure-flow waveform and hemodynamic energy level in a neonatal pulsatile centrifugal pump

Wang, S., Haines, N., Richardson, J. S., Dasse, K. A. & Ündar, A., May 1 2009, In : ASAIO Journal. 55, 3, p. 277-281 5 p.

Research output: Contribution to journalArticle

Centrifugal pumps
Hemodynamics
Electron energy levels
Pumps
Pressure
7 Citations (Scopus)

Impact of Translational Research on Optimization of Neonatal Cardiopulmonary Bypass Circuits and Techniques—The Penn State Health Approach

Ündar, A., Wang, S., Palanzo, D. A., Wise, R., Woitas, K., Baer, L. D., Kunselman, A. R., Clark, J. B. & Myers, J. L., Mar 1 2017, In : Artificial organs. 41, 3, p. 218-223 6 p.

Research output: Contribution to journalArticle

Oxygenators
Health
Networks (circuits)
15 Citations (Scopus)

Impact of tubing length on hemodynamics in a simulated neonatal extracorporeal life support circuit

Qiu, F., Uluer, M. C., Kunselman, A., Clark, J. B., Myers, J. L. & Ündar, A., Nov 1 2010, In : Artificial organs. 34, 11, p. 1003-1009 7 p.

Research output: Contribution to journalArticle

Extracorporeal Membrane Oxygenation
Hemodynamics
Tubing
Networks (circuits)
Pressure drop
32 Citations (Scopus)

Improved cerebral oxygen saturation and blood flow pulsatility with pulsatile perfusion during pediatric cardiopulmonary bypass

Su, X. W., Guan, Y., Barnes, M., Clark, J. B., Myers, J. & Undar, A., Aug 1 2011, In : Pediatric Research. 70, 2, p. 181-185 5 p.

Research output: Contribution to journalArticle

Pulsatile Flow
Cardiopulmonary Bypass
Near-Infrared Spectroscopy
Pediatrics
Oxygen
2 Citations (Scopus)

Improved Mathematical Model of APA Microcapsules

He, Y., Xie, Y. B., Wang, Y., Liu, Q. & Ma, X. J., Feb 10 2000, In : Kao Teng Hsueh Hsiao Hua Heush Hsueh Pao/ Chemical Journal of Chinese Universities. 21, 2, 1 p.

Research output: Contribution to journalArticle

Capsules
Mathematical models
Membranes
Proteins
alginate-polylysine-alginate
11 Citations (Scopus)

Improved microchip design and application for in situ transmission electron microscopy of macromolecules

Dukes, M. J., Thomas, R., Damiano, J., Klein, K. L., Balasubramaniam, S., Kayandan, S., Riffle, J. S., Davis, R. M., McDonald, S. M. & Kelly, D., Jan 1 2014, In : Microscopy and Microanalysis. 20, 2, p. 338-345 8 p.

Research output: Contribution to journalArticle

Macromolecules
macromolecules
Transmission electron microscopy
transmission electron microscopy
reagents
14 Citations (Scopus)

Impulsive Enzymes: A New Force in Mechanobiology

Butler, P. J., Dey, K. K. & Sen, A., Jan 1 2015, In : Cellular and Molecular Bioengineering. 8, 1, p. 106-118 13 p.

Research output: Contribution to journalArticle

Mechanobiology
Biophysics
Enzymes
Myosin Type II
Immobilized Enzymes
6 Citations (Scopus)

Impurity transport in parametrically excited capillary ripples

Aronson, I., Ezersky, A. B., Rabinovich, M. I. & Tsimring, L. S., Mar 4 1991, In : Physics Letters A. 153, 4-5, p. 211-218 8 p.

Research output: Contribution to journalArticle

ripples
impurities
exponents
modulation
13 Citations (Scopus)

Inactivation of creatine kinase is due to the conformational changes of the active sites during thermal denaturation

Bai, J. H., Zheng, S. & Zhou, H. M., Aug 1 1998, In : Biochemistry and Molecular Biology International. 45, 5, p. 941-951 11 p.

Research output: Contribution to journalArticle

Denaturation
Creatine Kinase
Catalytic Domain
Hot Temperature
Enzymes
27 Citations (Scopus)
Tendons
Plasticity
Mechanics
Tissue
Plastics
6 Citations (Scopus)

Increased Cardiac Arrhythmogenesis Associated with Gap Junction Remodeling with Upregulation of RNA-Binding Protein FXR1

Chu, M., Novak, S. M., Cover, C., Wang, A. A., Chinyere, I. R., Juneman, E. B., Zarnescu, D. C., Wong, P. K. & Gregorio, C. C., Feb 6 2018, In : Circulation. 137, 6, p. 605-618 14 p.

Research output: Contribution to journalArticle

RNA-Binding Proteins
Gap Junctions
Up-Regulation
Dilated Cardiomyopathy
Heart Diseases
1 Citation (Scopus)

Increased circulating microparticles in streptozotocin-induced diabetes propagate inflammation contributing to microvascular dysfunction

Feng, Q., Stork, C. J., Xu, S., Yuan, D., Xia, X., LaPenna, K. B., Guo, G., Sun, H., Xu, L. C., Siedlecki, C. A., Brundage, K. M., Sheaffer, N., Schell, T. D. & He, P., Feb 1 2019, In : Journal of Physiology. 597, 3, p. 781-798 18 p.

Research output: Contribution to journalArticle

Experimental Diabetes Mellitus
Inflammation
Microvessels
Phosphatidylserines
Blood Vessels
3 Citations (Scopus)

Increased Expression and Modulated Regulatory Activity of Coinhibitory Receptors PD-1, TIGIT, and TIM-3 in Lymphocytes From Patients With Systemic Sclerosis

Fleury, M., Belkina, A. C., Proctor, E. A., Zammitti, C., Simms, R. W., Lauffenburger, D. A., Snyder-Cappione, J. E., Lafyatis, R. & Dooms, H., Apr 1 2018, In : Arthritis and Rheumatology. 70, 4, p. 566-577 12 p.

Research output: Contribution to journalArticle

Programmed Cell Death 1 Receptor
Systemic Scleroderma
Lymphocytes
T-Lymphocytes
Cytokines
4 Citations (Scopus)

Increased O-GlcNAcylation of SNAP29 drives arsenicinduced autophagic dysfunction

Dodson, M., Liu, P., Jiang, T., Ambrose, A. J., Luo, G., de la Vega, M. R., Cholanians, A. B., Wong, P. K., Chapman, E. & Zhang, D. D., Jun 1 2018, In : Molecular and cellular biology. 38, 11, e00595-17.

Research output: Contribution to journalArticle

Arsenic
SNARE Proteins
Autophagy
Lysosomes
Clustered Regularly Interspaced Short Palindromic Repeats
22 Citations (Scopus)

Individual behavior and pairwise interactions between microswimmers in anisotropic liquid

Sokolov, A., Zhou, S., Lavrentovich, O. D. & Aranson, I. S., Jan 15 2015, In : Physical Review E - Statistical, Nonlinear, and Soft Matter Physics. 91, 1, 013009.

Research output: Contribution to journalArticle

Bacteria
bacteria
Pairwise
Liquid
Liquid Crystal
3 Citations (Scopus)

Individual variability in behavior and functional networks predicts vulnerability using an animal model of PTSD

Dopfel, D., Perez, P. D., Verbitsky, A., Bravo-Rivera, H., Ma, Y., Quirk, G. J. & Zhang, N., Dec 1 2019, In : Nature communications. 10, 1, 2372.

Research output: Contribution to journalArticle

Open Access
animal models
vulnerability
Post-Traumatic Stress Disorders
predators
Animals
11 Citations (Scopus)

Inducing Heat Shock Proteins Enhances the Stemness of Frozen-Thawed Adipose Tissue-Derived Stem Cells

Shaik, S., Hayes, D., Gimble, J. & Devireddy, R., Apr 15 2017, In : Stem Cells and Development. 26, 8, p. 608-616 9 p.

Research output: Contribution to journalArticle

Stromal Cells
Heat-Shock Proteins
Adipose Tissue
Stem Cells
Cryopreservation
216 Citations (Scopus)

Inflammation- and ischemia-induced shedding of venular glycocalyx

Mulivor, A. W. & Lipowsky, H. H., May 1 2004, In : American Journal of Physiology - Heart and Circulatory Physiology. 286, 5 55-5, p. H1672-H1680

Research output: Contribution to journalArticle

Glycocalyx
Glycosaminoglycans
Ischemia
Inflammation
Pertussis Toxin
17 Citations (Scopus)

Inflammatory and hemostatic response to cardiopulmonary bypass in pediatric population: Feasibility of seriological testing of multiple biomarkers

Aĝirbaşli, M., Nguyen, M. L., Win, K., Kunselman, A., Clark, J. B., Myers, J. & Undar, A., Nov 1 2010, In : Artificial organs. 34, 11, p. 987-995 9 p.

Research output: Contribution to journalArticle

Pediatrics
Biomarkers
Hemostatics
Cardiopulmonary Bypass
Testing
26 Citations (Scopus)

Influence of Ca2+ on force redevelopment kinetics in skinned rat myocardium

Hancock, W. O., Martyn, D. A., Huntsman, L. L. & Gordon, A. M., Jun 1996, In : Biophysical journal. 70, 6, p. 2819-2829 11 p.

Research output: Contribution to journalArticle

Myocardium
Architectural Accessibility
Muscles
Sarcomeres
Myosins
83 Citations (Scopus)

Influence of cell deformation on leukocyte rolling adhesion in shear flow

Lei, X., Lawrence, M. B. & Dong, C., Dec 1999, In : Journal of Biomechanical Engineering. 121, 6, p. 636-643 8 p.

Research output: Contribution to journalArticle

Leukocyte Rolling
Shear flow
Adhesion
Fluids
Shear stress
97 Citations (Scopus)

Influence of erythrocyte aggregation on leukocyte margination in postcapillary venules of rat mesentery

Pearson, M. J. & Lipowsky, H. H., Dec 7 2000, In : American Journal of Physiology - Heart and Circulatory Physiology. 279, 4 48-4, p. H1460-H1471

Research output: Contribution to journalArticle

Erythrocyte Aggregation
Mesentery
Venules
Leukocytes
Dextrans
21 Citations (Scopus)

Influence of gradient acoustic noise on fMRI response in the human visual cortex

Zhang, N., Zhu, X. H. & Chen, W., Aug 1 2005, In : Magnetic Resonance in Medicine. 54, 2, p. 258-263 6 p.

Research output: Contribution to journalArticle

Visual Cortex
Acoustics
Noise
Magnetic Resonance Imaging
Light
25 Citations (Scopus)

Influence of hydrophobic face amino acids on the hydrogelation of -hairpin peptide amphiphiles

Micklitsch, C. M., Medina, S. H., Yucel, T., Nagy-Smith, K. J., Pochan, D. J. & Schneider, J. P., Mar 10 2015, In : Macromolecules. 48, 5, p. 1281-1288 8 p.

Research output: Contribution to journalArticle

Amphiphiles
Peptides
Amino acids
Amino Acids
Gels
1 Citation (Scopus)

Influence of thickness and permeability of endothelial surface layer on transmission of shear stress in capillaries

Zhang, S. P., Zhang, X. J., Tian, Y., Meng, Y. G. & Lipowsky, H., Jul 13 2015, In : Science China: Physics, Mechanics and Astronomy. 58, 7

Research output: Contribution to journalArticle

shear stress
surface layers
permeability
fluids
matrices
7 Citations (Scopus)

Inherited Disease Genetics Improves the Identification of Cancer-Associated Genes

Zhao, B. & Pritchard, J. R., Jun 2016, In : PLoS genetics. 12, 6, e1006081.

Research output: Contribution to journalArticle

Inborn Genetic Diseases
Neoplasm Genes
genetic disorders
cancer
Exome
22 Citations (Scopus)

Inhibition of bacterial adhesion and biofilm formation by dual functional textured and nitric oxide releasing surfaces

Xu, L. C., Wo, Y., Meyerhoff, M. E. & Siedlecki, C. A., Mar 15 2017, In : Acta Biomaterialia. 51, p. 53-65 13 p.

Research output: Contribution to journalArticle

Bacterial Adhesion
Nitric oxide
Biofilms
Biocompatible Materials
Polyurethanes
69 Citations (Scopus)

Inhibition of complement, neutrophil, and platelet activation by an anti-factor D monoclonal antibody in simulated cardiopulmonary bypass circuits

Fung, M., Loubser, P. G., Ündar, A., Mueller, M., Sun, C., Sun, W. N., Vaughn, W. K. & Fraser, C. D., Jul 1 2001, In : Journal of Thoracic and Cardiovascular Surgery. 122, 1, p. 113-122 10 p.

Research output: Contribution to journalArticle

Complement Factor D
Neutrophil Activation
Complement Activation
Platelet Activation
Cardiopulmonary Bypass