• United States

Research Output 1974 2019

2018
5 Citations (Scopus)

A new textured polyphosphazene biomaterial with improved blood coagulation and microbial infection responses

Xu, L., Li, Z., Tian, Z., Chen, C., Allcock, H. R. & Siedlecki, C., Feb 1 2018, In : Acta Biomaterialia. 67, p. 87-98 12 p.

Research output: Contribution to journalArticle

Biocompatible Materials
Blood Coagulation
Coagulation
Biomaterials
Bacterial Adhesion
3 Citations (Scopus)

An experimental and computational study of the inferior vena cava hemodynamics under respiratory-induced collapse of the infrarenal IVC

Tedaldi, E., Montanari, C., Aycock, K. I., Sturla, F., Redaelli, A. & Manning, K. B., Apr 1 2018, In : Medical Engineering and Physics. 54, p. 44-55 12 p.

Research output: Contribution to journalArticle

Hemodynamics
Inferior Vena Cava
Vena Cava Filters
Computational fluid dynamics
Flow rate
1 Citation (Scopus)

Animal Models for Pediatric Mechanical Circulatory Support Research at Penn State Health

Izer, J., Wilson, R., Clark, J., Myers, J., Weiss, W. & Undar, A., Apr 1 2018, In : Artificial Organs. 42, 4, p. 347-353 7 p.

Research output: Contribution to journalEditorial

Artificial heart
Artificial Heart
Extracorporeal Membrane Oxygenation
Pediatrics
Heart-Assist Devices
1 Citation (Scopus)

Anomalous gray matter structural networks in recent onset post-traumatic stress disorder

Qi, S., Mu, Y. F., Cui, L. B., Zhang, J., Guo, F., Tan, Q. R., Shi, M., Liu, K., Xi, Y. B., Zhang, N., Zhang, X. L., He, Y., Yang, J. & Yin, H., Apr 1 2018, In : Brain Imaging and Behavior. 12, 2, p. 390-401 12 p.

Research output: Contribution to journalArticle

Post-Traumatic Stress Disorders
Occipital Lobe
Prefrontal Cortex
Parahippocampal Gyrus
Gyrus Cinguli

Anti-microbial peptide facilitated cytosolic delivery of metallic gold nanomaterials

Kapur, A., Wang, W., Diaz Hernandez, J., Medina, S. H., Schneider, J. P. & Mattoussi, H., Jan 1 2018, Colloidal Nanoparticles for Biomedical Applications XIII. Parak, W. J., Osinski, M. & Liang, X-J. (eds.). SPIE, 105070R. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 10507).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Nanostructures
Nanostructured materials
Gold
Nanoparticles
Nanocrystals

An Ultrasensitive Calcium Reporter System via CRISPR-Cas9-Mediated Genome Editing in Human Pluripotent Stem Cells

Jiang, Y., Zhou, Y., Bao, X., Chen, C., Randolph, L. N., Du, J. & Lian, X., Nov 30 2018, In : iScience. 9, p. 27-35 9 p.

Research output: Contribution to journalArticle

Open Access
Clustered Regularly Interspaced Short Palindromic Repeats
Cell Engineering
Pluripotent Stem Cells
Optical Imaging
Calcium

A Portable Device Integrated with Aligned Carbon Nanotubes for Sensitive Virus Capture and Detection

Yeh, Y-T., Lu, H., Zheng, S. & Terrones Maldonado, M., Oct 26 2018, 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2018. Institute of Electrical and Electronics Engineers Inc., Vol. 2018-July. p. 6072-6075 4 p. 8513515

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Carbon Nanotubes
Viruses
Carbon nanotubes
Point-of-Care Systems
Equipment and Supplies
16 Citations (Scopus)

Aptamer-conjugated extracellular nanovesicles for targeted drug delivery

Wan, Y., Wang, L., Zhu, C., Zheng, Q., Wang, G., Tong, J., Fang, Y., Xia, Y., Cheng, G., He, X. & Zheng, S., Feb 1 2018, In : Cancer Research. 78, 3, p. 798-808 11 p.

Research output: Contribution to journalArticle

Pharmaceutical Preparations
Ligands
Antigen Receptors
Drug Delivery Systems
Cell- and Tissue-Based Therapy
3 Citations (Scopus)

A single simulation platform for hybrid photoacoustic and RF-acoustic computed tomography

Fadden, C. & Kothapalli, S-R., Sep 6 2018, In : Applied Sciences (Switzerland). 8, 9, 1568.

Research output: Contribution to journalArticle

Thermoacoustics
Photoacoustic effect
Tomography
radio frequencies
platforms
15 Citations (Scopus)

A Spontaneous 3D Bone-On-a-Chip for Bone Metastasis Study of Breast Cancer Cells

Hao, S., Ha, L., Cheng, G., Wan, Y., Xia, Y., Sosnoski, D. M., Mastro, A. M. & Zheng, S., Mar 22 2018, In : Small. 14, 12, 1702787.

Research output: Contribution to journalArticle

Bone
Cells
Breast Neoplasms
Neoplasm Metastasis
Bone and Bones
6 Citations (Scopus)

Bone and plasma citrate is reduced in osteoporosis

Chen, H., Wang, Y., Dai, H., Tian, X., Cui, Z. K., Chen, Z., Hu, L., Song, Q., Liu, A., Zhang, Z., Xiao, G., Yang, J., Jiang, Y. & Bai, X., Sep 1 2018, In : Bone. 114, p. 189-197 9 p.

Research output: Contribution to journalArticle

Citric Acid
Osteoporosis
Bone and Bones
Bone Density
Pelvic Bones
2 Citations (Scopus)

Casein Kinase 1 Epsilon Regulates Glioblastoma Cell Survival

Varghese, R. T., Young, S., Pham, L., Liang, Y., Pridham, K. J., Guo, S., Murphy, S., Kelly, D. & Sheng, Z., Dec 1 2018, In : Scientific reports. 8, 1, 13621.

Research output: Contribution to journalArticle

Open Access
Casein Kinase Iepsilon
Glioblastoma
Cell Survival
Catenins
Stem Cells

Chapter 4: Directed differentiation of human pluripotent stem cells for therapeutic applications

Randolph, L. N., Witmer, E. B. & Lian, X., 2018, Frontiers in Nanobiomedical Research. World Scientific Publishing Co. Pte Ltd, Vol. 10. p. 75-100 26 p. (Frontiers in Nanobiomedical Research; vol. 10).

Research output: Chapter in Book/Report/Conference proceedingChapter

Pluripotent Stem Cells
Stem cells
Cell Lineage
Therapeutics
Intercellular Signaling Peptides and Proteins
1 Citation (Scopus)

Characterizing the HeartMate II left ventricular assist device outflow using particle image velocimetry

Rowlands, G. W., Good, B. C., Deutsch, S. & Manning, K. B., Jul 1 2018, In : Journal of Biomechanical Engineering. 140, 7, 071008.

Research output: Contribution to journalArticle

Left ventricular assist devices
Heart-Assist Devices
Rheology
Velocity measurement
von Willebrand Factor
8 Citations (Scopus)

Citrate-Based Fluorescent Biomaterials

Shan, D., Hsieh, J. T., Bai, X. & Yang, J., Sep 19 2018, In : Advanced Healthcare Materials. 7, 18, 1800532.

Research output: Contribution to journalReview article

Biocompatible Materials
Biomaterials
Citric Acid
Fluorescence
Optical Imaging
4 Citations (Scopus)

Citrate-based materials fuel human stem cells by metabonegenic regulation

Ma, C., Tian, X., Kim, J. P., Xie, D., Ao, X., Shan, D., Lin, Q., Hudock, M. R., Bai, X. & Yang, J., Dec 11 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 50, p. E11741-E11750

Research output: Contribution to journalArticle

Phosphoserine
Citric Acid
Stem Cells
Bone Regeneration
Mesenchymal Stromal Cells
7 Citations (Scopus)

Citrate chemistry and biology for biomaterials design

Ma, C., Gerhard, E., Lu, D. & Yang, J., Sep 1 2018, In : Biomaterials. 178, p. 383-400 18 p.

Research output: Contribution to journalArticle

Medical nanotechnology
Betaine
Biocompatible Materials
Biomaterials
Citric Acid
7 Citations (Scopus)

Co-activation patterns in resting-state fMRI signals

Liu, X., Zhang, N., Chang, C. & Duyn, J. H., Oct 15 2018, In : NeuroImage. 180, p. 485-494 10 p.

Research output: Contribution to journalReview article

Magnetic Resonance Imaging
Brain
3 Citations (Scopus)

Cold Active Motion: How Time-Independent Disorder Affects the Motion of Self-Propelled Agents

Peruani, F. & Aronson, I., Jun 6 2018, In : Physical Review Letters. 120, 23, 238101.

Research output: Contribution to journalArticle

disorders
particle trajectories
torque
equations of motion
trapping
2 Citations (Scopus)

Comparative proteomic analyses of human adipose extracellular matrices decellularized using alternative procedures

Thomas-Porch, C., Li, J., Zanata, F., Martin, E. C., Pashos, N., Genemaras, K., Poche, J. N., Totaro, N. P., Bratton, M. R., Gaupp, D., Frazier, T., Wu, X., Ferreira, L. M., Tian, W., Wang, G., Bunnell, B. A., Flynn, L., Hayes, D. J. & Gimble, J. M., Sep 1 2018, In : Journal of Biomedical Materials Research - Part A. 106, 9, p. 2481-2493 13 p.

Research output: Contribution to journalArticle

Scaffolds
Detergents
Tissue
Proteins
Mass spectrometry
2 Citations (Scopus)

Comparison of thermally actuated retro-diels-alder release groups for nanoparticle based nucleic acid delivery

Abu-Laban, M., Kumal, R. R., Casey, J., Becca, J., LaMaster, D., Pacheco, C. N., Sykes, D. G., Jensen, L., Haber, L. H. & Hayes, D. J., Sep 15 2018, In : Journal of Colloid And Interface Science. 526, p. 312-321 10 p.

Research output: Contribution to journalArticle

Nucleic acids
Thiophene
Nucleic Acids
Thiophenes
Pyrroles

Constrained Gaussian process with application in tissue-engineering scaffold biodegradation

Zeng, L., Deng, X. & Yang, J., May 4 2018, In : IISE Transactions. 50, 5, p. 431-447 17 p.

Research output: Contribution to journalArticle

Scaffolds (biology)
Biodegradation
Tissue engineering
Scaffolds
Fabrication
3 Citations (Scopus)

Construction of versatile multilayered composite nanoparticles from a customized nanogel template

Zhang, J., Jia, J., Kim, J. P., Yang, F., Wang, X., Shen, H., Xu, S., Yang, J. & Wu, D., Mar 1 2018, In : Bioactive Materials. 3, 1, p. 87-96 10 p.

Research output: Contribution to journalArticle

Nanoparticles
Composite materials
Periosteum
Oncology
Orthopedics
1 Citation (Scopus)

Contact activation by the intrinsic pathway of blood plasma coagulation

Yan, Y., Xu, L., Vogler, E. A. & Siedlecki, C., Jan 1 2018, Hemocompatibility of Biomaterials for Clinical Applications: Blood-Biomaterials Interactions. Elsevier Inc., p. 3-28 26 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Blood Coagulation
Enzyme Precursors
Biocompatible Materials
Fibrin
High Molecular Weight Kininogens
Biomedical engineering
Formability
Stem cells
8 Citations (Scopus)

Detection of sepsis in patient blood samples using CD64 expression in a microfluidic cell separation device

Zhang, Y., Li, W., Zhou, Y., Johnson, A., Venable, A., Hassan, A., Griswold, J. & Pappas, D., Jan 7 2018, In : Analyst. 143, 1, p. 241-249 9 p.

Research output: Contribution to journalArticle

Open Access
Microfluidics
Cell Separation
Sepsis
Blood
blood
2 Citations (Scopus)

Determination of Reynolds Shear Stress Level for Hemolysis

Jhun, C-S., Stauffer, M. A., Reibson, J. D., Yeager, E. E., Newswanger, R. K., Taylor, J. O., Manning, K. B., Weiss, W. & Rosenberg, G., Jan 1 2018, In : ASAIO journal (American Society for Artificial Internal Organs : 1992). 64, 1, p. 63-69 7 p.

Research output: Contribution to journalArticle

Hemolysis
Shear stress
Hemoglobin
Hemoglobins
Blood

Development of a Pain Scoring System for Use in Sheep Surgically Implanted with Ventricular Assist Devices

Izer, J., LaFleur, R. A., Weiss, W. & Wilson, R., Apr 11 2018, (Accepted/In press) In : Journal of Investigative Surgery. p. 1-10 10 p.

Research output: Contribution to journalArticle

Heart-Assist Devices
Sheep
Pain
Postoperative Pain
Biomedical Research

Development of brain-wide connectivity architecture in awake rats

Ma, Z., Ma, Y. & Zhang, N., Aug 1 2018, In : NeuroImage. 176, p. 380-389 10 p.

Research output: Contribution to journalArticle

Brain
Communication
Cerebral Dominance
Neuroanatomy
Cluster Analysis
5 Citations (Scopus)

Development of Citrate-Based Dual-Imaging Enabled Biodegradable Electroactive Polymers

Shan, D., Kothapalli, S-R., Ravnic, D., Gerhard, E., Kim, J. P., Guo, J., Ma, C., Guo, J., Gui, L., Sun, L., Lu, D. & Yang, J., Aug 22 2018, In : Advanced Functional Materials. 28, 34, 1801787.

Research output: Contribution to journalArticle

electroactive polymers
citrates
Citric Acid
Polymers
Photoacoustic effect
12 Citations (Scopus)

Development of tannin-inspired antimicrobial bioadhesives

Guo, J., Sun, W., Kim, J. P., Lu, X., Li, Q., Lin, M., Mrowczynski, O., Rizk, E., Cheng, J., Qian, G. & Yang, J., May 1 2018, In : Acta Biomaterialia. 72, p. 35-44 10 p.

Research output: Contribution to journalArticle

Tannins
Tissue
Acids
Silver
Gelatin
1 Citation (Scopus)

Diffusion-reaction kinetics of microfluidic amperometric biosensors

Li, H., Lu, Y. & Wong, P. K., Jan 1 2018, In : Lab on a Chip. 18, 20, p. 3086-3089 4 p.

Research output: Contribution to journalArticle

Microfluidics
Biosensing Techniques
Biosensors
Reaction kinetics
Self assembled monolayers
5 Citations (Scopus)

Engineered Healing of Avascular Meniscus Tears by Stem Cell Recruitment

Tarafder, S., Gulko, J., Sim, K. H., Yang, J., Cook, J. L. & Lee, C. H., Dec 1 2018, In : Scientific reports. 8, 1, 8150.

Research output: Contribution to journalArticle

Mesenchymal Stromal Cells
Stem Cells
Connective Tissue Growth Factor
Transforming Growth Factor beta
Wounds and Injuries
7 Citations (Scopus)

Engineering bacterial vortex lattice via direct laser lithography

Nishiguchi, D., Aronson, I., Snezhko, A. & Sokolov, A., Dec 1 2018, In : Nature communications. 9, 1, 4486.

Research output: Contribution to journalArticle

Lithography
bacteria
Bacteria
Vortex flow
Lasers

Enhanced Uptake of Luminescent Quantum Dots by Live Cells Mediated by a Membrane-Active Peptide

Kapur, A., Medina, S. H., Wang, W., Palui, G., Ji, X., Schneider, J. P. & Mattoussi, H., Dec 12 2018, In : ACS Omega. 3, 12, p. 17164-17172 9 p.

Research output: Contribution to journalArticle

Nanostructured materials
Peptides
Semiconductor quantum dots
Membranes
Imaging techniques

Erratum to: Engineering bacterial vortex lattice via direct laser lithography (Nature Communications, (2018), 9, 1, (4486), 10.1038/s41467-018-06842-6)

Nishiguchi, D., Aronson, I., Snezhko, A. & Sokolov, A., Dec 1 2018, In : Nature communications. 9, 1, 4932.

Research output: Contribution to journalComment/debate

Lithography
Labels
Vortex flow
Lasers
lithography

Erratum to: Achieving high permeability and enhanced selectivity for Angstrom-scale separations using artificial water channel membranes (Nature Communications, (2018), 9, 1, (2294), 10.1038/s41467-018-04604-y)

Shen, Y. X., Song, W., Barden, D. R., Ren, T., Lang, C., Feroz, H., Henderson, C. B., Saboe, P. O., Tsai, D., Yan, H., Butler, P. J., Bazan, G. C., Phillip, W. A., Hickey, III, R. J., Cremer, P. S., Vashisth, H. & Kumar, M., Dec 1 2018, In : Nature communications. 9, 1, 3304.

Research output: Contribution to journalComment/debate

document markup languages
Aquaporins
HTML
Music
Permeability
5 Citations (Scopus)

Evaluation and Comparison of Hemodynamic Performance of Three ECLS Systems in a Simulated Adult Cardiogenic Shock Model

Undar, A., Wang, S., Moroi, M., Kunselman, A. & Brehm, C., Aug 1 2018, In : Artificial organs. 42, 8, p. 776-785 10 p.

Research output: Contribution to journalArticle

Oxygenators
Cardiogenic Shock
Hemodynamics
Pulsatile Flow
Pulsatile flow
1 Citation (Scopus)

Evaluation of High Frequency Piezoelectric Micromachined Ultrasound Transducers for Photoacoustic Imaging

Dangi, A., Agrawal, S., Tiwari, S., Jadhav, S., Cheng, C., Trolier-McKinstry, S. E., Pratap, R. & Kothapalli, S-R., Dec 26 2018, 2018 IEEE SENSORS, SENSORS 2018 - Conference Proceedings. Institute of Electrical and Electronics Engineers Inc., 8589733. (Proceedings of IEEE Sensors; vol. 2018-October).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Photoacoustic effect
Transducers
Ultrasonics
Imaging techniques
Natural frequencies
9 Citations (Scopus)

Expansion of mesenchymal stem cells on electrospun scaffolds maintains stemness, mechano-responsivity, and differentiation potential

Heo, S. J., Szczesny, S., Kim, D. H., Saleh, K. S. & Mauck, R. L., Feb 1 2018, In : Journal of Orthopaedic Research. 36, 2, p. 808-815 8 p.

Research output: Contribution to journalArticle

Mesenchymal Stromal Cells
Plastics
Tissue Engineering
Tissue Scaffolds
Phenotype
5 Citations (Scopus)

Fatigue loading of tendon results in collagen kinking and denaturation but does not change local tissue mechanics

Szczesny, S., Aeppli, C., David, A. & Mauck, R. L., Apr 11 2018, In : Journal of Biomechanics. 71, p. 251-256 6 p.

Research output: Contribution to journalArticle

Denaturation
Tendons
Mechanics
Collagen
Fatigue

From cancer immunoediting to new strategies in cancer immunotherapy: The roles of immune cells and mechanics in oncology

Aragon-Sanabria, V., Kim, G. B. & Dong, C., Jan 1 2018, Advances in Experimental Medicine and Biology. Springer New York LLC, p. 113-138 26 p. (Advances in Experimental Medicine and Biology; vol. 1092).

Research output: Chapter in Book/Report/Conference proceedingChapter

Oncology
Mechanics
Immunotherapy
Tumors
Neoplasms
12 Citations (Scopus)

Functional atlas of the awake rat brain: A neuroimaging study of rat brain specialization and integration

Ma, Z., Perez, P., Ma, Z., Liu, Y., Hamilton, C., Liang, Z. & Zhang, N., Apr 15 2018, In : NeuroImage. 170, p. 95-112 18 p.

Research output: Contribution to journalArticle

Atlases
Neuroimaging
Brain
Neuroanatomy
Gyrus Cinguli
2 Citations (Scopus)

Functional performance of different venous limb options in simulated neonatal/pediatric cardiopulmonary bypass circuits

Caneo, L. F., Matte, G. S., Guimarães, D. P., Viotto, G., Mazzeto, M., Cestari, I., Neirotti, R. A., Jatene, M. B., Wang, S., Undar, A., Chang Junior, J. & Jatene, F. B., May 1 2018, In : Brazilian Journal of Cardiovascular Surgery. 33, 3, p. 224-232 9 p.

Research output: Contribution to journalArticle

Cardiopulmonary Bypass
Extremities
Pediatrics
Oxygenators
Hemodilution
5 Citations (Scopus)

Fundamentals of affinity cell separations

Zhang, Y., Lyons, V. & Pappas, D., Mar 1 2018, In : ELECTROPHORESIS. 39, 5-6, p. 732-741 10 p.

Research output: Contribution to journalReview article

Cell Separation
Cell Adhesion
Cell Communication
Temperature
Cell adhesion

Guest Editorial Advancing Mechanobiology by Micro/Nanosystems

Sun, Y., Kim, D. H. & Wong, P. K., May 1 2018, In : IEEE Transactions on Nanotechnology. 17, 3, p. 371-372 2 p.

Research output: Contribution to journalEditorial

Nanosystems
2 Citations (Scopus)

Harnessing Medium Anisotropy to Control Active Matter

Aronson, I., Dec 18 2018, In : Accounts of Chemical Research. 51, 12, p. 3023-3030 8 p.

Research output: Contribution to journalArticle

Liquid Crystals
Anisotropy
Suspensions
Bacteria
Bacterial Toxins
7 Citations (Scopus)

Highly photostable nanogels for fluorescence-based theranostics

Gyawali, D., Kim, J. P. & Yang, J., Mar 1 2018, In : Bioactive Materials. 3, 1, p. 39-47 9 p.

Research output: Contribution to journalArticle

Fluorescence
Biodegradable polymers
Biodegradability
Citric acid
Cell death
1 Citation (Scopus)

High-resolution single-molecule kinesin assays at kHz frame rates

Mickolajczyk, K. J. & Hancock, W. O., Jan 1 2018, Methods in Molecular Biology. Humana Press Inc., p. 123-138 16 p. (Methods in Molecular Biology; vol. 1805).

Research output: Chapter in Book/Report/Conference proceedingChapter

Adenylyl Imidodiphosphate
Kinesin
Gold
Nanoparticles
In Vitro Techniques

Human Beta Cells Generated from Pluripotent Stem Cells or Cellular Reprogramming for Curing Diabetes

Randolph, L. N., Bhattacharyya, A. & Lian, X., Jan 1 2018, (Accepted/In press) In : Regenerative Engineering and Translational Medicine.

Research output: Contribution to journalArticle

Pluripotent Stem Cells
Medical problems
Stem cells
Curing
Insulin