• United States

Research Output 1974 2019

2017
6 Citations (Scopus)

Development of a Dual-Functional Hydrogel Using RGD and Anti-VEGF Aptamer

Zhao, N., Battig, M. R., Xu, M., Wang, X., Xiong, N. & Wang, Y., Nov 2017, In : Macromolecular Bioscience. 17, 11, 1700201.

Research output: Contribution to journalArticle

Hydrogel
Biocompatible Materials
Biomaterials
Hydrogels
Vascular Endothelial Growth Factor A
5 Citations (Scopus)

Development of a platelet adhesion transport equation for a computational thrombosis model

Taylor, J. O., Yang, L., Deutsch, S. & Manning, K. B., Jan 4 2017, In : Journal of Biomechanics. 50, p. 114-120 7 p.

Research output: Contribution to journalArticle

Platelets
Thrombosis
Blood Platelets
Adhesion
Biocompatible Materials
1 Citation (Scopus)

Development of microwave and impedance spectroscopy methods for in-situ nondestructive evaluation of alkali silica reaction in concrete

Heifetz, A., Bakhtiari, S., Lu, J., Aronson, I., Vinokur, V. M. & Bentivegna, A. F., Feb 16 2017, 43rd Annual Review of Progress in Quantitative Nondestructive Evaluation, Volume 36. Bond, L. J. & Chimenti, D. E. (eds.). American Institute of Physics Inc., Vol. 1806. 120003

Research output: Chapter in Book/Report/Conference proceedingConference contribution

alkalies
impedance
silicon dioxide
microwaves
evaluation
4 Citations (Scopus)

Directed differentiation and long-term maintenance of epicardial cells derived from human pluripotent stem cells under fully defined conditions

Bao, X., Lian, X., Qian, T., Bhute, V. J., Han, T. & Palecek, S. P., Sep 1 2017, In : Nature Protocols. 12, 9, p. 1890-1900 11 p.

Research output: Contribution to journalArticle

Pluripotent Stem Cells
Stem cells
Cells
Flow cytometry
Transforming Growth Factors

Directed differentiation of human pluripotent stem cells for therapeutic applications

Randolph, L. N., Witmer, E. B. & Lian, X., Jan 1 2017, Tissue Engineering and Nanotheranostics. World Scientific Publishing Co. Pte Ltd, p. 75-100 26 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Pluripotent Stem Cells
Stem cells
Cell Lineage
Therapeutics
Intercellular Signaling Peptides and Proteins
3 Citations (Scopus)

Direct Lattice Shaking of Bose Condensates: Finite Momentum Superfluids

Anderson, B. M., Clark, L. W., Crawford, J., Glatz, A., Aronson, I., Scherpelz, P., Feng, L., Chin, C. & Levin, K., May 31 2017, In : Physical Review Letters. 118, 22, 220401.

Research output: Contribution to journalArticle

shaking
condensates
momentum
destabilization
platforms
4 Citations (Scopus)

Displacement and hybridization reactions in aptamer-functionalized hydrogels for biomimetic protein release and signal transduction

Lai, J., Li, S., Shi, X., Coyne, J., Zhao, N., Dong, F., Mao, Y. & Wang, Y., Jan 1 2017, In : Chemical Science. 8, 11, p. 7306-7311 6 p.

Research output: Contribution to journalArticle

Signal transduction
Hydrogels
Biomimetics
Molecules
Hydrogel
24 Citations (Scopus)

Dynamic Connectivity Patterns in Conscious and Unconscious Brain

Ma, Y., Hamilton, C. & Zhang, N., Feb 1 2017, In : Brain Connectivity. 7, 1, p. 1-12 12 p.

Research output: Contribution to journalArticle

Consciousness
Brain
Unconsciousness
Wakefulness
Neuroimaging
7 Citations (Scopus)

Dynamic self-assembly and self-organized transport of magnetic micro-swimmers

Kokot, G., Kolmakov, G. V., Aranson, I. S. & Snezhko, A., Dec 1 2017, In : Scientific reports. 7, 1, 14726.

Research output: Contribution to journalArticle

Magnetic Fields
Computer Simulation
9 Citations (Scopus)

Dynamic states of swimming bacteria in a nematic liquid crystal cell with homeotropic alignment

Zhou, S., Tovkach, O., Golovaty, D., Sokolov, A., Aronson, I. & Lavrentovich, O. D., May 1 2017, In : New Journal of Physics. 19, 5, 055006.

Research output: Contribution to journalArticle

bacteria
liquid crystals
alignment
cells
Bacillus
2 Citations (Scopus)

Effective encapsulation and biological activity of phosphorylated chemotherapeutics in calcium phosphosilicate nanoparticles for the treatment of pancreatic cancer

Loc, W. S., Linton, S. S., Wilczynski, Z. R., Matters, G., McGovern, C. O., Abraham, T., Fox, T., Gigliotti, C. M., Tang, X., Tabakovic, A., Martin, J. A., Clawson, G., Smith, J. P., Butler, P. J., Kester, M. & Adair, J. H., Oct 1 2017, In : Nanomedicine: Nanotechnology, Biology, and Medicine. 13, 7, p. 2313-2324 12 p.

Research output: Contribution to journalArticle

Bioactivity
Pancreatic Neoplasms
Encapsulation
Nanoparticles
Calcium
9 Citations (Scopus)

Eg5 Inhibitors Have Contrasting Effects on Microtubule Stability and Metaphase Spindle Integrity

Chen, G. Y., Kang, Y. J., Gayek, A. S., Youyen, W., Tüzel, E., Ohi, R. & Hancock, W. O., Apr 21 2017, In : ACS chemical biology. 12, 4, p. 1038-1046 9 p.

Research output: Contribution to journalArticle

Kinesin
Metaphase
Microtubules
Assays
Antimitotic Agents
14 Citations (Scopus)

Enhanced anticancer efficacy of paclitaxel through multistage tumor-targeting liposomes modified with RGD and KLA peptides

Sun, J., Jiang, L., Lin, Y., Gerhard, E. M., Jiang, X., Li, L., Yang, J. & Gu, Z., Feb 27 2017, In : International Journal of Nanomedicine. 12, p. 1517-1537 21 p.

Research output: Contribution to journalArticle

Liposomes
Lip
Paclitaxel
Peptides
Tumors
12 Citations (Scopus)

Enhanced Diffusion of Passive Tracers in Active Enzyme Solutions

Zhao, X., Dey, K. K., Jeganathan, S., Butler, P. J., Córdova-Figueroa, U. M. & Sen, A., Aug 9 2017, In : Nano letters. 17, 8, p. 4807-4812 6 p.

Research output: Contribution to journalArticle

Energy transfer
tracers
enzymes
Enzymes
energy transfer
3 Citations (Scopus)

Evaluating a novel dimensional reduction approach for mechanical fractionation of cells using a tandem flexible micro spring array (tFMSA)

Yeh, Y-T., Harouaka, R. A. & Zheng, S., Jan 1 2017, In : Lab on a Chip. 17, 4, p. 691-701 11 p.

Research output: Contribution to journalArticle

Cell Fractionation
Fractionation
Cells
Formability
Mechanical properties
9 Citations (Scopus)

Evidence that interfibrillar load transfer in tendon is supported by small diameter fibrils and not extrafibrillar tissue components

Szczesny, S., Fetchko, K. L., Dodge, G. R. & Elliott, D. M., Oct 1 2017, In : Journal of Orthopaedic Research. 35, 10, p. 2127-2134 8 p.

Research output: Contribution to journalArticle

Tendon Transfer
Collagen
Tendons
Mechanics
Trypsin
34 Citations (Scopus)

Exothermicity Is Not a Necessary Condition for Enhanced Diffusion of Enzymes

Illien, P., Zhao, X., Dey, K. K., Butler, P. J., Sen, A. & Golestanian, R., Jul 12 2017, In : Nano letters. 17, 7, p. 4415-4420 6 p.

Research output: Contribution to journalArticle

enzymes
Enzymes
aldolase
Substrates
Fructose-Bisphosphate Aldolase
4 Citations (Scopus)

Exposure to buffer solution alters tendon hydration and mechanics

Safa, B. N., Meadows, K. D., Szczesny, S. & Elliott, D. M., Aug 16 2017, In : Journal of Biomechanics. 61, p. 18-25 8 p.

Research output: Contribution to journalArticle

Tendons
Mechanics
Hydration
Buffers
Polyethylene glycols
3 Citations (Scopus)

Ex-situ up-conversion of biomass pyrolysis bio-oil vapors using Pt/Al2O3 nanostructured catalyst synergistically heated with steel balls via induction

Abu-Laban, M., Muley, P. D., Hayes, D. J. & Boldor, D., Jan 1 2017, In : Catalysis Today. 291, p. 3-12 10 p.

Research output: Contribution to journalArticle

Steel
Electric tapes
Oils
Biomass
Pyrolysis
8 Citations (Scopus)

Fabrication and characterization of cell sheets using methylcellulose and PNIPAAm thermoresponsive polymers: A comparison Study

Forghani, A., Kriegh, L., Hogan, K., Chen, C., Brewer, G., Tighe, T. B., Devireddy, R. & Hayes, D. J., May 1 2017, In : Journal of Biomedical Materials Research - Part A. 105, 5, p. 1346-1354 9 p.

Research output: Contribution to journalArticle

Methylcellulose
Stem cells
Polymers
Fabrication
Osteocalcin
25 Citations (Scopus)

FDA Benchmark Medical Device Flow Models for CFD Validation

Malinauskas, R. A., Hariharan, P., Day, S. W., Herbertson, L. H., Buesen, M., Steinseifer, U., Aycock, K. I., Good, B. C., Deutsch, S., Manning, K. B. & Craven, B. A., Jan 1 2017, In : ASAIO Journal. 63, 2, p. 150-160 11 p.

Research output: Contribution to journalArticle

Benchmarking
United States Food and Drug Administration
Hydrodynamics
Computational fluid dynamics
Equipment and Supplies

Finite element analysis on stellite 17mm tube valve for pediatric ventricular assist device

Scheib, C. M., Newswanger, R. K., Beese, A. M., Bowen, T., Lewis, G., Roush, E. P., Jhun, C-S., Weiss, W. & Rosenberg, G., Jan 1 2017, Frontiers in Biomedical Devices, BIOMED - 2017 Design of Medical Devices Conference, DMD 2017. American Society of Mechanical Engineers, (Frontiers in Biomedical Devices, BIOMED - 2017 Design of Medical Devices Conference, DMD 2017).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Stellite
Pediatrics
Finite element method
2 Citations (Scopus)

Flagella bending affects macroscopic properties of bacterial suspensions

Potomkin, M., Tournus, M., Berlyand, L. V. & Aronson, I., May 1 2017, In : Journal of the Royal Society Interface. 14, 130, 20161031.

Research output: Contribution to journalArticle

Flagella
Suspensions
Bacteria
Viscosity
Barreling
24 Citations (Scopus)

Flexible biodegradable citrate-based polymeric step-index optical fiber

Shan, D., Zhang, C., Kalaba, S., Mehta, N., Kim, G. B., Liu, Z. & Yang, J., Oct 1 2017, In : Biomaterials. 143, p. 142-148 7 p.

Research output: Contribution to journalArticle

Optical Fibers
Citric Acid
Optical fibers
Tissue
Light
36 Citations (Scopus)

Flocking ferromagnetic colloids

Kaiser, A., Snezhko, A. & Aronson, I., Feb 1 2017, In : Science Advances. 3, 2, e1601469.

Research output: Contribution to journalArticle

Colloids
Magnetic Fields
Biopolymers
Hydrodynamics
Birds
14 Citations (Scopus)

Fluorous Phase-Directed Peptide Assembly Affords Nano-Peptisomes Capable of Ultrasound-Triggered Cellular Delivery

Medina, S. H., Michie, M. S., Miller, S. E., Schnermann, M. J. & Schneider, J. P., Jan 1 2017, In : Angewandte Chemie - International Edition. 56, 38, p. 11404-11408 5 p.

Research output: Contribution to journalArticle

Peptides
Ultrasonics
Biological Products
Nanoparticles
3 Citations (Scopus)

Focusing of active particles in a converging flow

Potomkin, M., Kaiser, A., Berlyand, L. V. & Aronson, I., Nov 1 2017, In : New Journal of Physics. 19, 11, 115005.

Research output: Contribution to journalArticle

upstream
nozzles
fluid flow
trajectories
trapezoids
10 Citations (Scopus)

Genital-systemic chemokine gradients and the risk of HIV acquisition in women

Liebenberg, L. J. P., Masson, L., Arnold, K. B., McKinnon, L. R., Werner, L., Proctor, E. A., Archary, D., Mansoor, L. E., Lauffenburger, D. A., Karim, Q. A., Karim, S. S. A. & Passmore, J. A. S., Mar 1 2017, In : Journal of Acquired Immune Deficiency Syndromes. 74, 3, p. 318-325 8 p.

Research output: Contribution to journalArticle

Chemokines
HIV
Odds Ratio
Interleukin-8
Confidence Intervals
11 Citations (Scopus)

Global reduction of information exchange during anesthetic-induced unconsciousness

Hamilton, C., Ma, Y. & Zhang, N., Sep 1 2017, In : Brain Structure and Function. 222, 7, p. 3205-3216 12 p.

Research output: Contribution to journalArticle

Unconsciousness
Anesthetics
Isoflurane
Brain
Magnetic Resonance Imaging
9 Citations (Scopus)

Glycan Alteration Imparts Cellular Resistance to a Membrane-Lytic Anticancer Peptide

Ishikawa, K., Medina, S. H., Schneider, J. P. & Klar, A. J. S., Feb 16 2017, In : Cell Chemical Biology. 24, 2, p. 149-158 10 p.

Research output: Contribution to journalArticle

Polysaccharides
Cells
Membranes
Peptides
Tumors
Biocompatible Materials
Research
Technology
Equipment and Supplies
18 Citations (Scopus)

Immune Cell-Mediated Biodegradable Theranostic Nanoparticles for Melanoma Targeting and Drug Delivery

Xie, Z., Su, Y., Kim, G. B., Selvi, E., Ma, C., Aragon-Sanabria, V., Hsieh, J. T., Dong, C. & Yang, J., Mar 14 2017, In : Small. 13, 10, 1603121.

Research output: Contribution to journalArticle

Drug Delivery Systems
Drug delivery
Nanoparticles
Melanoma
Macrophages
1 Citation (Scopus)
Biomedical engineering
Engineering research
Students
Curricula
Education
7 Citations (Scopus)

Impact of Translational Research on Optimization of Neonatal Cardiopulmonary Bypass Circuits and Techniques—The Penn State Health Approach

Ündar, A., Wang, S., Palanzo, D. A., Wise, R., Woitas, K., Baer, L. D., Kunselman, A. R., Clark, J. B. & Myers, J. L., Mar 1 2017, In : Artificial organs. 41, 3, p. 218-223 6 p.

Research output: Contribution to journalArticle

Oxygenators
Induced Heart Arrest
Translational Medical Research
Cardiopulmonary Bypass
Catheterization
9 Citations (Scopus)

Inducing Heat Shock Proteins Enhances the Stemness of Frozen-Thawed Adipose Tissue-Derived Stem Cells

Shaik, S., Hayes, D. J., Gimble, J. & Devireddy, R., Apr 15 2017, In : Stem Cells and Development. 26, 8, p. 608-616 9 p.

Research output: Contribution to journalArticle

Stromal Cells
Heat-Shock Proteins
Adipose Tissue
Stem Cells
Cryopreservation
21 Citations (Scopus)

Inhibition of bacterial adhesion and biofilm formation by dual functional textured and nitric oxide releasing surfaces

Xu, L., Wo, Y., Meyerhoff, M. E. & Siedlecki, C., Mar 15 2017, In : Acta Biomaterialia. 51, p. 53-65 13 p.

Research output: Contribution to journalArticle

Bacterial Adhesion
Nitric oxide
Biofilms
Biocompatible Materials
Polyurethanes
8 Citations (Scopus)

Inhibition of inflammation induced shedding of the endothelial glycocalyx with low molecular weight heparin

Lipowsky, H. H. & Lescanic, A., Jul 1 2017, In : Microvascular Research. 112, p. 72-78 7 p.

Research output: Contribution to journalArticle

Glycocalyx
Low Molecular Weight Heparin
Endothelial cells
Endothelial Cells
Inflammation
14 Citations (Scopus)

Integrated Biosensor Assay for Rapid Uropathogen Identification and Phenotypic Antimicrobial Susceptibility Testing

Altobelli, E., Mohan, R., Mach, K. E., Sin, M. L. Y., Liao, J. C., Buscarini, M., Wong, P. K., Gau, V., Banaei, N. & Liao, J. C., Apr 1 2017, In : European Urology Focus. 3, 2-3, p. 293-299 7 p.

Research output: Contribution to journalArticle

Biosensing Techniques
Urinary Tract Infections
Microbial Sensitivity Tests
Ciprofloxacin
Anti-Bacterial Agents
3 Citations (Scopus)

Intercellular Tension Negatively Regulates Angiogenic Sprouting of Endothelial Tip Cells via Notch1-Dll4 Signaling

Wang, S., Sun, J., Xiao, Y., Lu, Y., Zhang, D. D. & Wong, P. K., Feb 1 2017, In : Advanced Biosystems. 1, 1-2, 1600019.

Research output: Contribution to journalArticle

Endothelial Cells
Blood Vessels
Biomechanics
Endothelial cells
Force control
11 Citations (Scopus)

Interhemispheric resting-state functional connectivity of the claustrum in the awake and anesthetized states

Smith, J. B., Liang, Z., Watson, G. D. R., Alloway, K. & Zhang, N., Jul 1 2017, In : Brain Structure and Function. 222, 5, p. 2041-2058 18 p.

Research output: Contribution to journalArticle

Basal Ganglia
Thalamus
Prefrontal Cortex
Magnetic Resonance Imaging
Anesthesia
11 Citations (Scopus)

Interleukin-13 conjugated quantum dots for identification of glioma initiating cells and their extracellular vesicles

Madhankumar, A., Mrowczynski, O. D., Patel, S. R., Weston, C. L., Zacharia, B., Glantz, M., Siedlecki, C., Xu, L. & Connor, J., Aug 1 2017, In : Acta Biomaterialia. 58, p. 205-213 9 p.

Research output: Contribution to journalArticle

Quantum Dots
Interleukin-13
Glioma
Exosomes
Semiconductor quantum dots
11 Citations (Scopus)

Investigating mechanisms of tendon damage by measuring multi-scale recovery following tensile loading

Lee, A. H., Szczesny, S., Santare, M. H. & Elliott, D. M., Jul 15 2017, In : Acta Biomaterialia. 57, p. 363-372 10 p.

Research output: Contribution to journalArticle

Tendons
Recovery
Pathology
Mechanical testing
Patient rehabilitation
21 Citations (Scopus)

Ionic Colloidal Molding as a Biomimetic Scaffolding Strategy for Uniform Bone Tissue Regeneration

Zhang, J., Jia, J., Kim, J. P., Shen, H., Yang, F., Zhang, Q., Xu, M., Bi, W., Wang, X., Yang, J. & Wu, D., May 3 2017, In : Advanced Materials. 29, 17, 1605546.

Research output: Contribution to journalArticle

Tissue regeneration
Biomimetics
Molding
Bone
Biocompatible Materials
15 Citations (Scopus)

Kinesin Processivity Is Determined by a Kinetic Race from a Vulnerable One-Head-Bound State

Mickolajczyk, K. J. & Hancock, W. O., Jun 20 2017, In : Biophysical journal. 112, 12, p. 2615-2623 9 p.

Research output: Contribution to journalArticle

Kinesin
Head
Microtubules
Static Electricity
Adenosine Triphosphatases
4 Citations (Scopus)

Label-Free Virus Capture and Release by a Microfluidic Device Integrated with Porous Silicon Nanowire Forest

Xia, Y., Tang, Y., Yu, X., Wan, Y., Chen, Y., Lu, H. & Zheng, S. Y., Feb 10 2017, In : Small. 13, 6, 1603135.

Research output: Contribution to journalArticle

Lab-On-A-Chip Devices
Nanowires
Virus Release
Porous silicon
Silicon
25 Citations (Scopus)

Long-term self-renewing human epicardial cells generated from pluripotent stem cells under defined xeno-free conditions

Bao, X., Lian, X., Hacker, T. A., Schmuck, E. G., Qian, T., Bhute, V. J., Han, T., Shi, M., Drowley, L., Plowright, A. T., Wang, Q. D., Goumans, M. J. & Palecek, S. P., Jan 10 2017, In : Nature Biomedical Engineering. 1, 1, 0003.

Research output: Contribution to journalArticle

Pluripotent Stem Cells
Stem cells
Pericardium
Regeneration
RNA Sequence Analysis
10 Citations (Scopus)

Mechanical function near defects in an aligned nanofiber composite is preserved by inclusion of disorganized layers: Insight into meniscus structure and function

Bansal, S., Mandalapu, S., Aeppli, C., Qu, F., Szczesny, S., Mauck, R. L. & Zgonis, M. H., Jul 1 2017, In : Acta Biomaterialia. 56, p. 102-109 8 p.

Research output: Contribution to journalArticle

Nanofibers
Tears
Scaffolds
Defects
Fibers
20 Citations (Scopus)

Mechanoresponsive stem cells to target cancer metastases through biophysical cues

Liu, L., Zhang, S. X., Liao, W., Farhoodi, H. P., Wong, C. W., Chen, C. C., Ségaliny, A. I., Chacko, J. V., Nguyen, L. P., Lu, M., Polovin, G., Pone, E. J., Downing, T. L., Lawson, D. A., Digman, M. A. & Zhao, W., Jul 26 2017, In : Science Translational Medicine. 9, 400

Research output: Contribution to journalArticle

Cues
Stem Cells
Neoplasm Metastasis
Neoplasms
Biophysics
8 Citations (Scopus)

Mechanotransmission in endothelial cells subjected to oscillatory and multi-directional shear flow

Dabagh, M., Jalali, P., Butler, P. J., Randles, A. & Tarbell, J. M., May 1 2017, In : Journal of the Royal Society Interface. 14, 130, 20170185.

Research output: Contribution to journalArticle

Endothelial cells
Shear flow
Adherens Junctions
Endothelial Cells
Shear stress
7 Citations (Scopus)

Membrane Protein Insertion into and Compatibility with Biomimetic Membranes

Ren, T., Erbakan, M., Shen, Y., Barbieri, E., Saboe, P., Feroz, H., Yan, H., McCuskey, S., Hall, J. F., Schantz, A. B., Bazan, G. C., Butler, P. J., Grzelakowski, M. & Kumar, M., Jul 1 2017, In : Advanced Biosystems. 1, 7, 1700053.

Research output: Contribution to journalArticle

Open Access
Biomimetics
Membrane Proteins
Proteins
Membranes
Aquaporins