• United States

Research Output 1974 2020

2016

Dynamic characterization of invasive leader cells during 3D collective cancer invasion

Dean, Z., Utzinger, U. & Wong, P. K., Jan 1 2016, 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016. Chemical and Biological Microsystems Society, p. 459-460 2 p. (20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Gene expression
Assays
Microscopic examination
Genes
17 Citations (Scopus)

Effect of the Pulsatile Extracorporeal Membrane Oxygenation on Hemodynamic Energy and Systemic Microcirculation in a Piglet Model of Acute Cardiac Failure

Itoh, H., Ichiba, S., Ujike, Y., Douguchi, T., Obata, H., Inamori, S., Iwasaki, T., Kasahara, S., Sano, S. & Ündar, A., Jan 1 2016, In : Artificial organs. 40, 1, p. 19-26 8 p.

Research output: Contribution to journalArticle

Microcirculation
Extracorporeal Membrane Oxygenation
Oxygenation
Hemodynamics
Heart Failure
11 Citations (Scopus)

Endothelin-1 supports clonal derivation and expansion of cardiovascular progenitors derived from human embryonic stem cells

Soh, B. S., Ng, S. Y., Wu, H., Buac, K., Park, J. H. C., Lian, X., Xu, J., Foo, K. S., Felldin, U., He, X., Nichane, M., Yang, H., Bu, L., Li, R. A., Lim, B. & Chien, K. R., Mar 8 2016, In : Nature communications. 7, 10774.

Research output: Contribution to journalArticle

stem cells
Endothelin-1
Stem cells
Blood Vessels
Muscle
8 Citations (Scopus)

Engineered kinesin motor proteins amenable to small-molecule inhibition

Engelke, M. F., Winding, M., Yue, Y., Shastry, S., Teloni, F., Reddy, S., Blasius, T. L., Soppina, P., Hancock, W. O., Gelfand, V. I. & Verhey, K. J., Apr 5 2016, In : Nature communications. 7, 11159.

Research output: Contribution to journalArticle

Kinesin
proteins
Molecules
molecules
Proteins
Cardiovascular Models
Pediatrics
Heart-Assist Devices
Hemodynamics
Blood
41 Citations (Scopus)

Exploiting Temporal Collateral Sensitivity in Tumor Clonal Evolution

Zhao, B., Sedlak, J. C., Srinivas, R., Creixell, P., Pritchard, J. R., Tidor, B., Lauffenburger, D. A. & Hemann, M. T., Mar 24 2016, In : Cell. 165, 1, p. 234-246 13 p.

Research output: Contribution to journalArticle

Clonal Evolution
Tumors
Drug Resistance
Pharmaceutical Preparations
Pharmacology
20 Citations (Scopus)

Fluorescence imaging enabled poly(lactide-co-glycolide)

Hu, J., Guo, J., Xie, Z., Shan, D., Gerhard, E., Qian, G. & Yang, J., Jan 1 2016, In : Acta Biomaterialia. 29, p. 307-319 13 p.

Research output: Contribution to journalArticle

Polyglactin 910
Optical Imaging
Fluorescence
Imaging techniques
Photobleaching
5 Citations (Scopus)

Functionalization of Polyurethane/Urea Copolymers with Amide Groups by Polymer Treatment with Ammonia Plasma

Vesel, A., Zaplotnik, R., Primc, G., Liu, X., Xu, K., Chen, K. C., Wei, C. & Mozetic, M., May 1 2016, In : Plasma Chemistry and Plasma Processing. 36, 3, p. 835-848 14 p.

Research output: Contribution to journalArticle

Polyurethanes
ureas
Amides
Ammonia
Urea
39 Citations (Scopus)

G-Fresnel smartphone spectrometer

Zhang, C., Cheng, G., Edwards, P., Zhou, M. D., Zheng, S. & Liu, Z., Jan 1 2016, In : Lab on a Chip. 16, 2, p. 246-250 5 p.

Research output: Contribution to journalArticle

Miniaturization
Smartphones
Spectrometers
Assays
Proteins
33 Citations (Scopus)

Graphene-Templated Synthesis of Magnetic Metal Organic Framework Nanocomposites for Selective Enrichment of Biomolecules

Cheng, G., Wang, Z. G., Denagamage, S. & Zheng, S. Y., Apr 27 2016, In : ACS Applied Materials and Interfaces. 8, 16, p. 10234-10242 9 p.

Research output: Contribution to journalArticle

Graphite
Biomolecules
Graphene
Nanocomposites
Metals
7 Citations (Scopus)

Hemodynamics in a Pediatric Ascending Aorta Using a Viscoelastic Pediatric Blood Model

Good, B. C., Deutsch, S. & Manning, K. B., Apr 1 2016, In : Annals of Biomedical Engineering. 44, 4, p. 1019-1035 17 p.

Research output: Contribution to journalArticle

Pediatrics
Hemodynamics
Blood
Computational fluid dynamics
Pulsatile flow
10 Citations (Scopus)

Human mesenchymal stem cell morphology and migration on microtextured titanium

Banik, B. L., Riley, T. R., Platt, C. J. & Brown, J. L., Jan 1 2016, In : Frontiers in Bioengineering and Biotechnology. 4, MAY, 41.

Research output: Contribution to journalArticle

Titanium
Stem cells
Mesenchymal Stromal Cells
Cell Movement
Polyether ether ketones
9 Citations (Scopus)

Human pluripotent stem cell culture density modulates YAP signaling

Hsiao, C., Lampe, M., Nillasithanukroh, S., Han, W., Lian, X. & Palecek, S. P., May 1 2016, In : Biotechnology Journal. 11, 5, p. 662-675 14 p.

Research output: Contribution to journalArticle

Pluripotent Stem Cells
Cell Culture Techniques
Cell Count
Small Interfering RNA
Phosphorylation
3 Citations (Scopus)

Impact of Pulsatile Flow on Vital Organ Recovery During Cardiopulmonary Bypass in Neonates and Infants

Ündar, A., Wang, S., Palanzo, D. A., Wise, R. K., Woitas, K., Baer, L. D., Kunselman, A. R., Song, J., Alkan-Bozkaya, T., Akcevin, A., Spencer, S., Agirbasli, M., Clark, J. B. & Myers, J. L., Jan 1 2016, In : Artificial organs. 40, 1, p. 14-18 5 p.

Research output: Contribution to journalEditorial

Cardiovascular Models
Cardiac Surgical Procedures
Membrane Oxygenators
Equipment Design
Pulsatile Flow
7 Citations (Scopus)

Inherited Disease Genetics Improves the Identification of Cancer-Associated Genes

Zhao, B. & Pritchard, J. R., Jun 2016, In : PLoS genetics. 12, 6, e1006081.

Research output: Contribution to journalArticle

Inborn Genetic Diseases
Neoplasm Genes
genetic disorders
cancer
Exome
9 Citations (Scopus)

Interferometric Scattering Microscopy for the Study of Molecular Motors

Andrecka, J., Takagi, Y., Mickolajczyk, K. J., Lippert, L. G., Sellers, J. R., Hancock, W. O., Goldman, Y. E. & Kukura, P., Jan 1 2016, Methods in Enzymology. Academic Press Inc., p. 517-539 23 p. (Methods in Enzymology; vol. 581).

Research output: Chapter in Book/Report/Conference proceedingChapter

Microscopy
Microscopic examination
Scattering
Metal Nanoparticles
Dyneins
3 Citations (Scopus)

Interrogating Canonical Wnt Signaling Pathway in Human Pluripotent Stem Cell Fate Decisions Using CRISPR-Cas9

Lian, X., Xu, J., Bao, X. & Randolph, L. N., Sep 1 2016, In : Cellular and Molecular Bioengineering. 9, 3, p. 325-334 10 p.

Research output: Contribution to journalArticle

Clustered Regularly Interspaced Short Palindromic Repeats
Pluripotent Stem Cells
Wnt Signaling Pathway
Stem Cells
Signaling Pathways
3 Citations (Scopus)

In vitro evaluation of thermal frontally polymerized thiol-ene composites as bone augments

Totaro, N. P., Murphy, Z. D., Burcham, A. E., King, C. T., Scherr, T. F., Bounds, C. O., Dasa, V., Pojman, J. A. & Hayes, D. J., Aug 1 2016, In : Journal of Biomedical Materials Research - Part B Applied Biomaterials. 104, 6, p. 1152-1160 9 p.

Research output: Contribution to journalArticle

Knee prostheses
Sulfhydryl Compounds
Bone
Polymerization
Bone cement
4 Citations (Scopus)
Oxygenators
Cardiopulmonary Bypass
Hemodynamics
Embolism
Air
7 Citations (Scopus)

Kinesin-2 and Apc function at dendrite branch points to resolve microtubule collisions

Weiner, A. T., Lanz, M. C., Goetschius, D. J., Hancock, W. O. & Rolls, M. M., Jan 1 2016, In : Cytoskeleton. 73, 1, p. 35-44 10 p.

Research output: Contribution to journalArticle

Kinesin
Dendrites
Microtubules
Neurons
9 Citations (Scopus)

Lattice Boltzmann simulation of asymmetric flow in nematic liquid crystals with finite anchoring

Zhang, R., Roberts, T., Aranson, I. S. & De Pablo, J. J., Feb 28 2016, In : Journal of Chemical Physics. 144, 8, 084905.

Research output: Contribution to journalArticle

Nematic liquid crystals
Shear deformation
Hydrodynamics
liquid crystals
Flow rate
18 Citations (Scopus)

Long-range electrothermal fluid motion in microfluidic systems

Lu, Y., Ren, Q., Liu, T., Leung, S. L., Gau, V., Liao, J. C., Chan, C. L. & Wong, P. K., Jul 1 2016, In : International Journal of Heat and Mass Transfer. 98, p. 341-349 9 p.

Research output: Contribution to journalArticle

Microfluidics
alternating current
Fluids
fluids
Joule heating
15 Citations (Scopus)

Loss of CSL Unlocks a Hypoxic Response and Enhanced Tumor Growth Potential in Breast Cancer Cells

Braune, E. B., Tsoi, Y. L., Phoon, Y. P., Landor, S., Silva Cascales, H., Ramsköld, D., Deng, Q., Lindqvist, A., Lian, X., Sahlgren, C., Jin, S. B. & Lendahl, U., May 10 2016, In : Stem Cell Reports. 6, 5, p. 643-651 9 p.

Research output: Contribution to journalArticle

Tumors
Cells
Breast Neoplasms
Growth
Stem cells

Measurement of aquaporin Z compatibility with biomimetic membranes using a developed membrane protein compatibility evaluation method

Ren, T., Erbakan, M., Grzelakowski, M., Butler, P. & Kumar, M., Jan 1 2016, 26th Annual Meeting of the North American Membrane Society, NAMS 2016. North American Membrane Society, p. 210-211 2 p. (26th Annual Meeting of the North American Membrane Society, NAMS 2016).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Aquaporins
Biomimetics
Membrane Proteins
Membranes
16 Citations (Scopus)

Mechanically Induced Chromatin Condensation Requires Cellular Contractility in Mesenchymal Stem Cells

Heo, S. J., Han, W. M., Szczesny, S. E., Cosgrove, B. D., Elliott, D. M., Lee, D. A., Duncan, R. L. & Mauck, R. L., Aug 23 2016, In : Biophysical journal. 111, 4, p. 864-874 11 p.

Research output: Contribution to journalArticle

Mesenchymal Stromal Cells
Chromatin
Adenosine Triphosphate
Transforming Growth Factors
Actomyosin
1 Citation (Scopus)

Mechanotransduction of shear stress by the endothelium

Butler, P. J., Jan 1 2016, Vascular Engineering: New Prospects of Vascular Medicine and Biology with a Multidiscipline Approach. Springer Japan, p. 159-197 39 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Endothelial cells
Endothelium
Shear stress
Endothelial Cells
Blood
10 Citations (Scopus)

Membrane tension feedback on shape and motility of eukaryotic cells

Winkler, B., Aranson, I. S. & Ziebert, F., Apr 1 2016, In : Physica D: Nonlinear Phenomena. 318-319, p. 26-33 8 p.

Research output: Contribution to journalArticle

locomotion
membranes
cells
conservation
polymerization
28 Citations (Scopus)

Mesenchymal stem cells engineered to express selectin ligands and IL-10 exert enhanced therapeutic efficacy in murine experimental autoimmune encephalomyelitis

Liao, W., Pham, V., Liu, L., Riazifar, M., Pone, E. J., Zhang, S. X., Ma, F., Lu, M., Walsh, C. M. & Zhao, W., Jan 1 2016, In : Biomaterials. 77, p. 87-97 11 p.

Research output: Contribution to journalArticle

Selectins
Autoimmune Experimental Encephalomyelitis
Stem cells
Mesenchymal Stromal Cells
Interleukin-10
9 Citations (Scopus)

Microfluidic cell surface antigen expression analysis using a single antibody type

Zhang, Y. & Pappas, D., Feb 21 2016, In : Analyst. 141, 4, p. 1440-1447 8 p.

Research output: Contribution to journalArticle

Microfluidics
Surface Antigens
Antigens
antigen
Antibodies
19 Citations (Scopus)

Microfluidic devices for terahertz spectroscopy of live cells toward lab-on-a-chip applications

Tang, Q., Liang, M., Lu, Y., Wong, P. K., Wilmink, G. J., Zhang, D. & Xin, H., Apr 4 2016, In : Sensors (Switzerland). 16, 4, 476.

Research output: Contribution to journalArticle

Lab-On-A-Chip Devices
Terahertz Spectroscopy
Terahertz spectroscopy
Lab-on-a-chip
T-cells
5 Citations (Scopus)

Microrobotics: Swimmers by design

Aranson, I. S., Mar 16 2016, In : Nature. 531, 7594, p. 312-313 2 p.

Research output: Contribution to journalShort survey

Robotics
robotics
Magnetic Fields
design method
science and technology
4 Citations (Scopus)

Molecularly Regulated Reversible DNA Polymerization

Chen, N., Shi, X. & Wang, Y., Jun 1 2016, In : Angewandte Chemie - International Edition. 55, 23, p. 6657-6661 5 p.

Research output: Contribution to journalArticle

Polymers
DNA
Polymerization
Natural polymers
Nucleic acids
7 Citations (Scopus)
Open Access
Tendons
Mechanics
Scaffolds
Tissue
Mesenchymal Stromal Cells
7 Citations (Scopus)

Mutant B-Raf(V600E) promotes melanoma paracellular transmigration by inducing thrombin-mediated endothelial junction breakdown

Zhang, P., Feng, S., Liu, G., Wang, H., Zhu, H., Ren, Q., Bai, H., Fu, C. & Dong, C., Jan 29 2016, In : Journal of Biological Chemistry. 291, 5, p. 2087-2106 20 p.

Research output: Contribution to journalArticle

Thrombin
Melanoma
Adherens Junctions
Phosphorylation
Ubiquitination
7 Citations (Scopus)

Nicotinamide is an endogenous agonist for a C. elegans TRPV OSM-9 and OCR-4 channel

Upadhyay, A., Pisupati, A., Jegla, T., Crook, M., Mickolajczyk, K. J., Shorey, M., Rohan, L. E., Billings, K. A., Rolls, M. M., Hancock, W. O. & Hanna-Rose, W., Oct 12 2016, In : Nature communications. 7, 13135.

Research output: Contribution to journalArticle

nicotinamide
Optical character recognition
Niacinamide
Drosophila
Caenorhabditis elegans
42 Citations (Scopus)

Nonnative SOD1 trimer is toxic to motor neurons in a model of amyotrophic lateral sclerosis

Proctor, E. A., Fee, L., Tao, Y., Redler, R. L., Fay, J. M., Zhang, Y., Lv, Z., Mercer, I. P., Deshmukh, M., Lyubchenko, Y. L. & Dokholyan, N. V., Jan 19 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 3, p. 614-619 6 p.

Research output: Contribution to journalArticle

Poisons
Amyotrophic Lateral Sclerosis
Motor Neurons
Mutation
Disease Progression
1 Citation (Scopus)

Novel Applications of Urethane/Urea Chemistry in the Field of Biomaterials

Kim, G. B., Guo, J., Hu, J., Shan, D. & Yang, J., Feb 2 2016, Advances in Polyurethane Biomaterials. Elsevier Inc., p. 115-147 33 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Urethane
Biocompatible Materials
Urea
Polyurethanes
Isocyanates
8 Citations (Scopus)

Obesity inhibits the osteogenic differentiation of human adipose-derived stem cells

Strong, A. L., Hunter, R. S., Jones, R. B., Bowles, A. C., Dutreil, M. F., Gaupp, D., Hayes, D. J., Gimble, J. M., Levi, B., McNulty, M. A. & Bunnell, B. A., Jan 27 2016, In : Journal of Translational Medicine. 14, 1, 27.

Research output: Contribution to journalArticle

Stromal Cells
Stem cells
Stem Cells
Obesity
Tissue Engineering
16 Citations (Scopus)

Patient-derived glioblastoma stem cells respond differentially to targeted therapies

Kanabur, P., Guo, S., Simonds, G. R., Kelly, D. F., Gourdie, R. G., Verbridge, S. S. & Sheng, Z., Jan 1 2016, In : Oncotarget. 7, 52, p. 86406-86419 14 p.

Research output: Contribution to journalArticle

Open Access
Glioblastoma
Stem Cells
Therapeutics
temozolomide
Cell Line

Physica D: Nonlinear Phenomena: Editorial

Ziebert, F. & Aronson, I., Apr 1 2016, In : Physica D: Nonlinear Phenomena. 318-319, p. 1-2 2 p.

Research output: Contribution to journalEditorial

multiphase flow
elastic properties
anisotropy
8 Citations (Scopus)

Plasmon-Enhanced Photocleaving Dynamics in Colloidal MicroRNA-Functionalized Silver Nanoparticles Monitored with Second Harmonic Generation

Kumal, R. R., Abu-Laban, M., Landry, C. R., Kruger, B., Zhang, Z., Hayes, D. J. & Haber, L. H., Oct 11 2016, In : Langmuir. 32, 40, p. 10394-10401 8 p.

Research output: Contribution to journalArticle

Harmonic generation
MicroRNAs
Silver
harmonic generations
silver
90 Citations (Scopus)

Polymeric nanoparticles: The future of nanomedicine

Banik, B. L., Fattahi, P. & Brown, J. L., Mar 1 2016, In : Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology. 8, 2, p. 271-299 29 p.

Research output: Contribution to journalReview article

Nanomedicine
Medical nanotechnology
Nanoparticles
Neurodegenerative Diseases
Nanosystems
6 Citations (Scopus)

Potential Danger of Pre-Pump Clamping on Negative Pressure-Associated Gaseous Microemboli Generation During Extracorporeal Life Support-An In Vitro Study

Wang, S., Chin, B. J., Gentile, F., Kunselman, A. R., Palanzo, D. & Ündar, A., Jan 1 2016, In : Artificial organs. 40, 1, p. 89-94 6 p.

Research output: Contribution to journalArticle

Extracorporeal Membrane Oxygenation
Oxygenators
Constriction
Pumps
Tubing
5 Citations (Scopus)

Preliminary study of light-cured hydrogel for endodontic drug delivery vehicle

Komabayashi, T., Wadajkar, A., Santimano, S., Ahn, C., Zhu, Q., Opperman, L. A., Bellinger, L. L., Yang, J. & Nguyen, K. T., Feb 1 2016, In : Journal of investigative and clinical dentistry. 7, 1, p. 87-92 6 p.

Research output: Contribution to journalArticle

Hydrogel
Endodontics
Dental Pulp Capping
Light
Pharmaceutical Preparations
4 Citations (Scopus)

Probing 3D collective cancer invasion using double-stranded locked nucleic acid biosensors

Dean, Z. S., Elias, P., Jamilpour, N., Utzinger, U. & Wong, P. K., Sep 6 2016, In : Analytical chemistry. 88, 17, p. 8902-8907 6 p.

Research output: Contribution to journalArticle

Biosensors
Gene expression
Microscopic examination
Genes
Monitoring
17 Citations (Scopus)

Probing Leader Cells in Endothelial Collective Migration by Plasma Lithography Geometric Confinement

Yang, Y., Jamilpour, N., Yao, B., Dean, Z. S., Riahi, R. & Wong, P. K., Mar 3 2016, In : Scientific reports. 6, 22707.

Research output: Contribution to journalArticle

Endothelial Cells
Cell Count
Adherens Junctions
Rheology
Endothelium
12 Citations (Scopus)

Prolonged particulate hexavalent chromium exposure suppresses homologous recombination repair in human lung cells

Browning, C. L., Qin, Q., Kelly, D. F., Prakash, R., Vanoli, F., Jasin, M. & Wise, J. P., Sep 1 2016, In : Toxicological Sciences. 153, 1, p. 70-78 9 p.

Research output: Contribution to journalArticle

Open Access
Recombinational DNA Repair
Repair
Lung
Chromosomal Instability
Double-Stranded DNA Breaks
8 Citations (Scopus)

Quantitative Analysis of Three-Dimensional Distribution and Clustering of Intramuscular Fat in Muscles of the Rotator Cuff

Santago, A. C., Vidt, M. E., Tuohy, C. J., Poehling, G. G., Freehill, M. T., Jordan, J. H., Kraft, R. A. & Saul, K. R., Jul 1 2016, In : Annals of Biomedical Engineering. 44, 7, p. 2158-2167 10 p.

Research output: Contribution to journalArticle

Oils and fats
Muscle
Chemical analysis
Magnetic resonance imaging
Pathology
20 Citations (Scopus)

Rapid expulsion of microswimmers by a vortical flow

Sokolov, A. & Aranson, I. S., Mar 23 2016, In : Nature communications. 7, 11114.

Research output: Contribution to journalArticle

expulsion
bacteria
Bacteria
microparticles
Shear flow
2 Citations (Scopus)

Rapid hydrophilization of model polyurethane/urea (PURPEG) polymer scaffolds using oxygen plasma treatment

Zaplotnik, R., Vesel, A., Primc, G., Liu, X., Chen, K. C., Wei, C., Xu, K. & Mozetic, M., Jan 1 2016, In : Polymers. 8, 4, 144.

Research output: Contribution to journalArticle

Polyurethanes
Scaffolds
Urea
Polymers
Oxygen