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Research Output 1974 2019

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Review article
2019
1 Citation (Scopus)

Cellular Based Strategies for Microvascular Engineering

Koduru, S., Leberfinger, A. N., Pasic, D., Forghani, A., Lince, S., Hayes, D. J., Ozbolat, I. T. & Ravnic, D., Apr 15 2019, In : Stem Cell Reviews and Reports. 15, 2, p. 218-240 23 p.

Research output: Contribution to journalReview article

Blood Vessels
Tissue Engineering
Microvessels
Microtechnology
Microfluidics
Nanofibers
Scaffolds
Tissue Engineering
Tissue
Stem cells

The blood compatibility challenge. Part 3: Material associated activation of blood cascades and cells

Gorbet, M., Sperling, C., Maitz, M. F., Siedlecki, C., Werner, C. & Sefton, M. V., Aug 1 2019, In : Acta Biomaterialia. 94, p. 25-32 8 p.

Research output: Contribution to journalReview article

Blood Cells
Thrombosis
Blood
Chemical activation
Dissent and Disputes
2018
1 Citation (Scopus)

Acquired Von Willebrand Syndrome and Blood Pump Design

Rosenberg, G., Siedlecki, C., Jhun, C-S., Weiss, W., Manning, K. B., Deutsch, S. & Pierce, W., Dec 1 2018, In : Artificial organs. 42, 12, p. 1119-1124 6 p.

Research output: Contribution to journalReview article

Heart-Assist Devices
Left ventricular assist devices
Blood
Pumps
Shear stress
3 Citations (Scopus)

Advanced Cell and Tissue Biomanufacturing

Ye, K., Kaplan, D. L., Bao, G., Bettinger, C., Forgacs, G., Dong, C., Khademhosseini, A., Ke, Y., Leong, K., Sambanis, A., Sun, W. & Yin, P., Jul 9 2018, In : ACS Biomaterials Science and Engineering. 4, 7, p. 2292-2307 16 p.

Research output: Contribution to journalReview article

Tissue
Biomedical engineering
Biotechnology
Industry
6 Citations (Scopus)

Citrate-Based Fluorescent Biomaterials

Shan, D., Hsieh, J. T., Bai, X. & Yang, J., Sep 19 2018, In : Advanced Healthcare Materials. 7, 18, 1800532.

Research output: Contribution to journalReview article

Biocompatible Materials
Biomaterials
Citric Acid
Fluorescence
Optical Imaging
7 Citations (Scopus)

Co-activation patterns in resting-state fMRI signals

Liu, X., Zhang, N., Chang, C. & Duyn, J. H., Oct 15 2018, In : NeuroImage. 180, p. 485-494 10 p.

Research output: Contribution to journalReview article

Magnetic Resonance Imaging
Brain
5 Citations (Scopus)

Fundamentals of affinity cell separations

Zhang, Y., Lyons, V. & Pappas, D., Mar 1 2018, In : ELECTROPHORESIS. 39, 5-6, p. 732-741 10 p.

Research output: Contribution to journalReview article

Cell Separation
Cell Adhesion
Cell Communication
Temperature
Cell adhesion
2 Citations (Scopus)

Mapping stress networks using functional magnetic resonance imaging in awake animals

Dopfel, D. & Zhang, N., Nov 1 2018, In : Neurobiology of Stress. 9, p. 251-263 13 p.

Research output: Contribution to journalReview article

Animals
Magnetic Resonance Imaging
Neurobiology
Longitudinal Studies
Endocrinology

Mitotic kinesins in action: diffusive searching, directional switching, and ensemble coordination

Gicking, A. M., Qiu, W. & Hancock, W. O., May 15 2018, In : Molecular biology of the cell. 29, 10, p. 1153-1156 4 p.

Research output: Contribution to journalReview article

Kinesin
Microtubules
Spindle Apparatus
Cell Division
Cell Biology
3 Citations (Scopus)

Polymeric biomaterials for biophotonic applications

Shan, D., Gerhard, E., Zhang, C., Tierney, J. W., Xie, D., Liu, Z. & Yang, J., Dec 1 2018, In : Bioactive Materials. 3, 4, p. 434-445 12 p.

Research output: Contribution to journalReview article

Optical materials
Biocompatible Materials
Biomaterials
Equipment Design
Optical Devices
17 Citations (Scopus)

Size-based separation methods of circulating tumor cells

Hao, S. J., Wan, Y., Xia, Y. Q., Zou, X. & Zheng, S., Feb 1 2018, In : Advanced Drug Delivery Reviews. 125, p. 3-20 18 p.

Research output: Contribution to journalReview article

Circulating Neoplastic Cells
Cell Separation
Exosomes
Technology
Neoplasms
2017
16 Citations (Scopus)

Design strategies and applications of nacre-based biomaterials

Gerhard, E. M., Wang, W., Li, C., Guo, J., Ozbolat, I. T., Rahn, K. M., Armstrong, A., Xia, J., Qian, G. & Yang, J., May 1 2017, In : Acta Biomaterialia. 54, p. 21-34 14 p.

Research output: Contribution to journalReview article

Nacre
Biocompatible Materials
Biomaterials
Tissue engineering
Bone
8 Citations (Scopus)

The Nuclear Option: Evidence Implicating the Cell Nucleus in Mechanotransduction

Szczesny, S. & Mauck, R. L., Feb 1 2017, In : Journal of Biomechanical Engineering. 139, 2, 020803.

Research output: Contribution to journalReview article

Cell Nucleus
Cells
Cytology
Mathematical models
Transcription factors
4 Citations (Scopus)

The use of nanoparticulates to treat breast cancer

Tang, X., Loc, W. S., Dong, C., Matters, G., Butler, P. J., Kester, M., Meyers, C., Jiang, Y. & Adair, J. H., Oct 1 2017, In : Nanomedicine. 12, 19, p. 2367-2388 22 p.

Research output: Contribution to journalReview article

Tumors
Breast Neoplasms
Oncology
Hemodynamics
Blood Circulation Time
23 Citations (Scopus)

Time to wake up: Studying neurovascular coupling and brain-wide circuit function in the un-anesthetized animal

Gao, Y. R., Ma, Y., Zhang, Q., Winder, A. T., Liang, Z., Antinori, L., Drew, P. J. & Zhang, N., Jun 1 2017, In : NeuroImage. 153, p. 382-398 17 p.

Research output: Contribution to journalReview article

Brain
Cerebrovascular Circulation
Animal Models
Magnetic Resonance Imaging
Neuroimaging
2016
23 Citations (Scopus)

Applications of Discrete Molecular Dynamics in biology and medicine

Proctor, E. A. & Dokholyan, N., Apr 1 2016, In : Current Opinion in Structural Biology. 37, p. 9-13 5 p.

Research output: Contribution to journalReview article

Molecular Dynamics Simulation
Medicine
Microcomputers
Proteostasis Deficiencies
Petroleum Pollution
15 Citations (Scopus)

Computational approaches to substrate-based cell motility

Ziebert, F. & Aronson, I., Jul 15 2016, In : npj Computational Materials. 2, 16019.

Research output: Contribution to journalReview article

Cell Motility
Self-healing materials
Substrate
Cells
Cell
28 Citations (Scopus)

Design strategies and applications of biomaterials and devices for Hernia repair

Kalaba, S., Gerhard, E., Winder, J. S., Pauli, E., Haluck, R. & Yang, J., Sep 1 2016, In : Bioactive Materials. 1, 1, p. 2-17 16 p.

Research output: Contribution to journalReview article

Herniorrhaphy
Biocompatible Materials
Biomaterials
Repair
Prostheses and Implants
65 Citations (Scopus)

Polymeric nanoparticles: The future of nanomedicine

Banik, B. L., Fattahi, P. & Brown, J. L., Mar 1 2016, In : Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology. 8, 2, p. 271-299 29 p.

Research output: Contribution to journalReview article

Nanomedicine
Medical nanotechnology
Nanoparticles
Neurodegenerative Diseases
Nanosystems
23 Citations (Scopus)

The Kinesin-1 Chemomechanical Cycle: Stepping Toward a Consensus

Hancock, W. O., Mar 29 2016, In : Biophysical journal. 110, 6, p. 1216-1225 10 p.

Research output: Contribution to journalReview article

Kinesin
Head
Tubulin
Microtubules
Binding Sites
2015
15 Citations (Scopus)

AC Electrokinetics of Physiological Fluids for Biomedical Applications

Lu, Y., Liu, T., Lamanda, A. C., Sin, M. L. Y., Gau, V., Liao, J. C. & Wong, P. K., Dec 1 2015, In : Journal of Laboratory Automation. 20, 6, p. 611-620 10 p.

Research output: Contribution to journalReview article

Microfluidics
Fluids
Delivery of Health Care
Health care
Electric fields
60 Citations (Scopus)

Design Strategies and Applications of Circulating Cell-Mediated Drug Delivery Systems

Su, Y., Xie, Z., Kim, G. B., Dong, C. & Yang, J., Dec 14 2015, In : ACS Biomaterials Science and Engineering. 1, 4, p. 201-217 17 p.

Research output: Contribution to journalReview article

Pharmaceutical Preparations
Controlled drug delivery
Medical nanotechnology
Stem cells
Drug delivery
2 Citations (Scopus)

Lipid bilayer control of nascent adhesion formation

Son, S. & Butler, P. J., Sep 1 2015, In : Biomedical Engineering Letters. 5, 3, p. 172-180 9 p.

Research output: Contribution to journalReview article

Lipid bilayers
Adhesion
Membranes
Cell adhesion
Surface diffusion
1 Citation (Scopus)

Micro-PIV measurements of the flow field around cells in flow chamber

Fu, Y., Wu, J. H., Wu, J., Sun, R., Ding, Z. R. & Dong, C., Oct 1 2015, In : Journal of Hydrodynamics. 27, 4, p. 562-568 7 p.

Research output: Contribution to journalReview article

flow chambers
particle image velocimetry
fibrin
Velocity measurement
Shear deformation
1 Citation (Scopus)

Multi-scale biological and physical modelling of the tumour micro-environment

Kunz, R. F., Gaskin, B. J., Li, Q., Davanloo-Tajbakhsh, S. & Dong, C., Feb 2 2015, In : Drug Discovery Today: Disease Models. 16, p. 7-15 9 p.

Research output: Contribution to journalReview article

Cell Communication
Computing Methodologies
Physics
Hydrodynamics
Biochemistry
88 Citations (Scopus)

Nucleic acid aptamers in cancer research, diagnosis and therapy

Ma, H., Liu, J., Ali, M. M., Mahmood, M. A. I., Labanieh, L., Lu, M., Iqbal, S. M., Zhang, Q., Zhao, W. & Wan, Y., Mar 7 2015, In : Chemical Society Reviews. 44, 5, p. 1240-1256 17 p.

Research output: Contribution to journalReview article

Nucleic Acids
Tumor Biomarkers
Structural design
Imaging techniques
Single-Stranded DNA
2014
154 Citations (Scopus)

Bidirectional cargo transport: Moving beyond tug of war

Hancock, W. O., Jan 1 2014, In : Nature Reviews Molecular Cell Biology. 15, 9, p. 615-628 14 p.

Research output: Contribution to journalReview article

Microtubules
Dyneins
Kinesin
Organelles
Direction compound
102 Citations (Scopus)

Circulating tumor cells: Advances in isolation and analysis, and challenges for clinical applications

Harouaka, R., Kang, Z., Zheng, S. & Cao, L., Feb 1 2014, In : Pharmacology and Therapeutics. 141, 2, p. 209-221 13 p.

Research output: Contribution to journalReview article

Circulating Neoplastic Cells
Neoplasms
Breast Neoplasms
Technology
Cell Separation
14 Citations (Scopus)

Computational approaches to understanding protein aggregation in neurodegeneration

Redler, R. L., Shirvanyants, D., Dagliyan, O., Ding, F., Kim, D. N., Kota, P., Proctor, E. A., Ramachandran, S., Tandon, A. & Dokholyan, N., Jan 1 2014, In : Journal of Molecular Cell Biology. 6, 2, p. 104-115 12 p.

Research output: Contribution to journalReview article

Proteins
Poisons
Amyotrophic Lateral Sclerosis
Information Systems
Neurodegenerative Diseases
36 Citations (Scopus)

New applications of disease genetics and pharmacogenetics to drug development

Roses, A. D., Saunders, A. M., Lutz, M. W., Zhang, N., Hariri, A. R., Asin, K. E., Crenshaw, D. G., Budur, K., Burns, D. K. & Brannan, S. K., Feb 1 2014, In : Current Opinion in Pharmacology. 14, 1, p. 81-89 9 p.

Research output: Contribution to journalReview article

pioglitazone
Inborn Genetic Diseases
Pharmacogenetics
Oxygen Consumption
Rodentia
2013
54 Citations (Scopus)

Design and application of magnetic-based theranostic nanoparticle systems

Wadajkar, A. S., Menon, J. U., Kadapure, T., Tran, R. T., Yang, J. & Nguyen, K. T., May 6 2013, In : Recent Patents on Biomedical Engineering. 6, 1, p. 47-57 11 p.

Research output: Contribution to journalReview article

Nanoparticles
Imaging techniques
Patents
Biomolecules
Magnetic resonance
49 Citations (Scopus)
Biocompatible Materials
Stem cells
Biomaterials
Scaffolds
Bone
2 Citations (Scopus)

Nanotopography sensing through intracellular signaling and mechanotransduction with an emphasis on bone

Higgins, A. M., Banik, B. L. & Brown, J. L., 2013, In : Journal of Biomaterials and Tissue Engineering. 3, 4, p. 396-408 13 p.

Research output: Contribution to journalReview article

Cell signaling
Topography
Bone
Bone and Bones
Substrates
27 Citations (Scopus)

Osteoinductive biomaterial geometries for bone regenerative engineering

Ozdemir, T., Higgins, A. M. & Brown, J. L., Dec 1 2013, In : Current Pharmaceutical Design. 19, 19, p. 3446-3455 10 p.

Research output: Contribution to journalReview article

Biocompatible Materials
Bone and Bones
Nanostructures
Bone Morphogenetic Proteins
Osteoblasts
2012
29 Citations (Scopus)

Understanding resistance to combination chemotherapy

Pritchard, J., Lauffenburger, D. A. & Hemann, M. T., Oct 1 2012, In : Drug Resistance Updates. 15, 5-6, p. 249-257 9 p.

Research output: Contribution to journalReview article

Combination Drug Therapy
Pharmaceutical Preparations
Neoplasms
Therapeutics
Investigational Therapies
2011
65 Citations (Scopus)

Disseminated and circulating tumor cells: Role in effective cancer management

Lin, H., Balic, M., Zheng, S., Datar, R. & Cote, R. J., Jan 1 2011, In : Critical Reviews in Oncology/Hematology. 77, 1, p. 1-11 11 p.

Research output: Contribution to journalReview article

Circulating Neoplastic Cells
Neoplasms
Microfluidics
Neoplastic Stem Cells
Cardiovascular System
20 Citations (Scopus)

Engineering tubulin: Microtubule functionalization approaches for nanoscale device applications

Malcos, J. L. & Hancock, W. O., Apr 1 2011, In : Applied Microbiology and Biotechnology. 90, 1, p. 1-10 10 p.

Research output: Contribution to journalReview article

Tubulin
Microtubules
Equipment and Supplies
Kinesin
Biological Transport
58 Citations (Scopus)

Nucleic acid aptamers for clinical diagnosis: Cell detection and molecular imaging

Soontornworajit, B. & Wang, Y., Feb 1 2011, In : Analytical and Bioanalytical Chemistry. 399, 4, p. 1591-1599 9 p.

Research output: Contribution to journalReview article

Molecular imaging
Molecular Imaging
Nucleic Acids
Imaging techniques
Flow cytometry
5 Citations (Scopus)

Pediatric Cardiopulmonary Bypass: Does Perfusion Mode Matter?

Talor, J. J. & Undar, A., Jan 1 2011, In : World Journal for Pediatric and Congenital Heart Surgery. 2, 2, p. 296-300 5 p.

Research output: Contribution to journalReview article

Pulsatile Flow
Cardiopulmonary Bypass
Perfusion
Pediatrics
Hemodynamics
26 Citations (Scopus)

Protease activity and the role of the endothelial glycocalyx in inflammation

Lipowsky, H. H., Jan 1 2011, In : Drug Discovery Today: Disease Models. 8, 1, p. 57-62 6 p.

Research output: Contribution to journalReview article

Glycocalyx
Peptide Hydrolases
Inflammation
Matrix Metalloproteinases
Endopeptidases
4 Citations (Scopus)

Remodeling and repair of orthopedic tissue: role of mechanical loading and biologics: part II: cartilage and bone.

Lee, C. S., Szczesny, S. & Soslowsky, L. J., Mar 2011, In : American journal of orthopedics (Belle Mead, N.J.). 40, 3, p. 122-128 7 p.

Research output: Contribution to journalReview article

Biological Products
Cartilage
Orthopedics
Bone and Bones
Homeostasis
10 Citations (Scopus)

The use of trehalose in the preparation of specimens for molecular electron microscopy

Chiu, P. L., Kelly, D. & Walz, T., Dec 1 2011, In : Micron. 42, 8, p. 762-772 11 p.

Research output: Contribution to journalReview article

Trehalose
Electron Microscopy
Electrons
Multiprotein Complexes
Negative Staining
2010
85 Citations (Scopus)

Aptamer-based molecular recognition for biosensor development

Zhou, J., Battig, M. R. & Wang, Y., Nov 1 2010, In : Analytical and Bioanalytical Chemistry. 398, 6, p. 2471-2480 10 p.

Research output: Contribution to journalReview article

Molecular recognition
Biosensing Techniques
Biosensors
Nucleic Acids
Ligands
8 Citations (Scopus)

Remodeling and repair of orthopedic tissue: role of mechanical loading and biologics.

Szczesny, S., Lee, C. S. & Soslowsky, L. J., Nov 2010, In : American journal of orthopedics (Belle Mead, N.J.). 39, 11, p. 525-530 6 p.

Research output: Contribution to journalReview article

Biological Products
Orthopedics
Homeostasis
Wounds and Injuries
2009
4 Citations (Scopus)

Penn state hershey - Center for pediatric cardiovascular research: Guest editorial

Undar, A., Pauliks, L., Clark, J., Zahn, J., Rosenberg, G., Kunselman, A., Sun, Q., Pekkan, K., Saliba, K., Carney, E., Thomas, N., Freeman, W., Vrana, K., El-Banayosy, A., Ural, S., Wilson, R., Umstead, T. M., Floros, J., Phelps, D., Weiss, W. & 15 others, Snyder, A., Yang, S., Kimatian, S., Cyran, S., Chinchilli, V., Guan, Y., Rider, A., Haines, N., Rogerson, A., Alkan-Bozkaya, T., Akcevin, A., Sun, K., Wang, S., Cun, L. & Myers, J., Nov 1 2009, In : Artificial organs. 33, 11, p. 883-887 5 p.

Research output: Contribution to journalReview article

Pediatrics
Research
Perfusion
Students
National Heart, Lung, and Blood Institute (U.S.)
1 Citation (Scopus)

Recent developments in nanoparticle based targeted delivery of chemotherapeutics

Peach, M. S., Kumbar, S. G., Brown, J. L. & Laurencin, C. T., Sep 1 2009, In : Current Bioactive Compounds. 5, 3, p. 170-184 15 p.

Research output: Contribution to journalReview article

Nanoparticles
Neoplasms
Nanotechnology
Drug Therapy
Radiation
2008
11 Citations (Scopus)

Bioengineering and bioinformatics summer institutes: Meeting modern challenges in undergraduate summer research

Butler, P. J., Dong, C., Snyder, A. J., Jones, A. D. & Sheets, E. D., Mar 1 2008, In : CBE Life Sciences Education. 7, 1, p. 45-53 9 p.

Research output: Contribution to journalReview article

Bioengineering
Bioinformatics
Computational Biology
Students
Research
2007
61 Citations (Scopus)

Directing transport of CoFe2O4-functionalized microtubules with magnetic fields

Hutchins, B. M., Platt, M., Hancock, W. O. & Williams, M. E., Jan 1 2007, In : Small. 3, 1, p. 126-131 6 p.

Research output: Contribution to journalReview article

Magnetic Fields
Microtubules
Kinesin
Magnetic fields
Optical tweezers
2006
10 Citations (Scopus)

Automated single-cell electroporation

Bae, C. & Butler, P. J., Oct 1 2006, In : BioTechniques. 41, 4, p. 399-402 4 p.

Research output: Contribution to journalReview article

Fluoresceins
Cell Membrane Permeability
Equipment Design
Electroporation
Vascular Endothelium