Research Output 1965 2019

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2019

(Not giving up) the marathon race of Met targeting therapy: Are we there yet?

Ma, P. C-C., Apr 15 2019, In : Clinical Cancer Research. 25, 8, p. 2375-2378 4 p.

Research output: Contribution to journalArticle

Biomarkers
Therapeutics

Absolute Quantification of All Identified Plasma Proteins from SWATH Data for Biomarker Discovery

Rice, S. J., Liu, X., Zhang, J. & Belani, C., Feb 1 2019, In : Proteomics. 19, 3, 1800135.

Research output: Contribution to journalArticle

Biomarkers
Blood Proteins
Proteins
Plasma (human)
Monitoring

Abstracts of Presentations at the Association of Clinical Scientists 139th Meeting Hershey, PA, May 15-18, 2019

Donaldson, K., Buchanich, J. M., Grigson-Kennedy, P. S., Deneke, E., Vrana, K., Sacks, D. B., Kuehn, G. J., Cardamone, D., Pesce, A., Smiley, S., Nickley, J., Krock, K., Thomas, R., Wilkerson, M. L., Farag, H. A., Challa, S. R., Tice, A. M., Wolk, D. M., Prichard, J., Grant, M. L. & 102 others, Regmi, S., Kerbacher, B., Quinton, L. E., Tice, A. M., Olson, J., Haynes, A., Yu, E., McCully, K. S., Assi, J., Wong, M., Zarrin-Khameh, N., Nifong, T. P., Hawker, C. D., Carlton, G. T., Rivera, J. M., Foulis, P. R., Zuraw, A., Morlote, D., Peker, D., Reddy, V., Harada, S., Crutchfield, C., Zander, D., Barbhuiya, M. A., Pederson, E. C., Straub, M. L., Scott, S. C., Neibauer, T. L., Salter, W. F., Creer, M. H., Zhu, Y., Bornhorst, J. A., Theobald, J. P., Algeciras-Schimnich, A., Cao, L., Knox, J., Hardy, R., Texas, H. J., McGuire, M. F., Hunter, R. L., Brown, R. E., Hicks, J., Cai, Z., Brown, R. E., Ali, Y., Cheng, K., Katz, S. R., Ding, Y., Vanselow, D. J., Yakovlev, M. A., Lin, A. Y., Clark, D. P., Vargas, P., Xin, X., Copper, J. E., Canfield, V., Ang, K., Wang, Y., Xiao, X., De Carlo, F., Van Rossum, D. B., La Rivière, P. J., Newell, J., Hossler, C., Roche, M., Warrick, J., Phaeton, R., Kesterson, J., Myers, C., Barrios, R., Mintz, P., Robyak, K., Hamilton, C., McGhee, P., Pederson, C., Straub, M., Scott, S., Neibauer, T., Salter, W., Robyak, K., Singh, N., Morlote, D., Vnencak-Jones, C., Yemelyanova, A., Harada, S., Shah, M., Moghadamtousi, S. Z., Lan, C., Duose, D., Hu, P., Esquenazi, Y., Luthra, R., Ballester, L. Y., Koenig, A. N., Liu, C. G., Zhang, J., Kalia, A., Al-Habib, A., Van Arsdall, M., Dhingra, S., Patel, K. & Tatevian, N., May 1 2019, In : Annals of clinical and laboratory science. 49, 3, p. 403-416 14 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

A calcium/cAMP signaling loop at the ORAI1 mouth drives channel inactivation to shape NFAT induction

Zhang, X., Pathak, T., Yoast, R., Emrich, S., Xin, P., Nwokonko, R. M., Johnson, M., Wu, S., Delierneux, C., Gueguinou, M., Hempel, N., Putney, J. W., Gill, D. & Trebak, M., Dec 1 2019, In : Nature communications. 10, 1, 1971.

Research output: Contribution to journalArticle

Open Access
Calcium Signaling
mouth
deactivation
Mouth
calcium

A central core disease mutation in the Ca2+-binding site of skeletal muscle ryanodine receptor impairs single-channel regulation

Chirasani, V. R., Xu, L., Addis, H. G., Pasek, D. A., Dokholyan, N., Meissner, G. & Yamaguchi, N., Aug 1 2019, In : American Journal of Physiology - Cell Physiology. 317, 2, p. C358-C365

Research output: Contribution to journalArticle

Central Core Myopathy
Ryanodine Receptor Calcium Release Channel
Skeletal Muscle
Binding Sites
Mutation
1 Citation (Scopus)

Acid ceramidase promotes drug resistance in acute myeloid leukemia through NF-κB-dependent P-glycoprotein upregulation

Tan, S. F., Dunton, W., Liu, X., Fox, T. E., Morad, S. A. F., Desai, D., Doi, K., Conaway, M. R., Amin, S., Claxton, D., Wang, H. G., Kester, M., Cabot, M. C., Feith, D. J. & Loughran, T. P., Jan 1 2019, In : Journal of Lipid Research. 60, 6, p. 1078-1086 9 p.

Research output: Contribution to journalArticle

Acid Ceramidase
P-Glycoprotein
Drug Resistance
Acute Myeloid Leukemia
Up-Regulation

Activation of Wnt signaling promotes olaparib resistant ovarian cancer

Yamamoto, T. M., McMellen, A., Watson, Z. L., Aguilera, J., Ferguson, R., Nurmemmedov, E., Thakar, T., Moldovan, G-L., Kim, H., Cittelly, D. M., Joglar, A. M., Brennecke, E. P., Wilson, H., Behbakht, K., Sikora, M. J. & Bitler, B. G., Oct 1 2019, In : Molecular Carcinogenesis. 58, 10, p. 1770-1782 13 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Carcinoma
Ovarian Diseases
Recombinational DNA Repair
Cell Line

Acupuncture for Hot Flashes in Cancer Patients: Clinical Characteristics and Traditional Chinese Medicine Diagnosis as Predictors of Treatment Response

Liu, W., Qdaisat, A., Lopez, G., Narayanan, S., Underwood, S., Spano, M., Reddy, A., Guo, Y., Zhou, S., Yeung, S. C., Bruera, E., Garcia, M. K. & Cohen, L., May 1 2019, In : Integrative Cancer Therapies. 18

Research output: Contribution to journalArticle

Open Access
Hot Flashes
Chinese Traditional Medicine
Acupuncture
Neoplasms
Acupuncture Therapy
1 Citation (Scopus)

Adaptable microfluidic system for single-cell pathogen classification and antimicrobial susceptibility testing

Li, H., Torab, P., Mach, K. E., Surrette, C., England, M. R., Craft, D., Thomas, N., Liao, J. C., Puleo, C. & Wong, P. K., Jan 1 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 21, p. 10270-10279 10 p.

Research output: Contribution to journalArticle

Microfluidics
Urine
Anti-Bacterial Agents
Bacteria
Bacterial Infections

Advanced NSCLC patients with high IL-6 levels have altered peripheral T cell population and signaling

Rice, S. J., Liu, X., Zhang, J., Jia, B., Zheng, H. & Belani, C., May 1 2019, In : Lung Cancer. 131, p. 58-61 4 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Interleukin-6
T-Lymphocytes
Population
STAT1 Transcription Factor

A Multiwell Microfluidic Device for Analyzing and Screening Nonhormonal Contraceptive Agents

Li, H., Garner, T., Diaz, F. & Wong, P. K., Jul 12 2019, In : Small. 15, 28, 1901910.

Research output: Contribution to journalArticle

Lab-On-A-Chip Devices
Contraceptive Agents
Microfluidics
Oocytes
Screening

A nonsense mutation in COL4A4 gene causing isolated hematuria in either heterozygous or homozygous state

Yang, C., Song, Y., Chen, Z., Yuan, X., Chen, X., Ding, G., Guan, Y., McGrath, M., Song, C., Tong, Y. & Wang, H., Jan 1 2019, In : Frontiers in Genetics. 10, JUL, 628.

Research output: Contribution to journalArticle

Open Access
Hereditary Nephritis
Nonsense Codon
Hematuria
Genes
Glomerular Basement Membrane
13 Citations (Scopus)

A pediatric regimen for older adolescents and young adults with acute lymphoblastic leukemia: Results of CALGB 10403

Stock, W., Luger, S. M., Advani, A. S., Yin, J., Harvey, R. C., Mullighan, C. G., Willman, C. L., Fulton, N., Laumann, K. M., Malnassy, G., Paietta, E., Parker, E., Geyer, S., Mrózek, K., Bloomfield, C. D., Sanford, B., Marcucci, G., Liedtke, M., Claxton, D., Foster, M. C. & 8 others, Bogart, J. A., Grecula, J. C., Appelbaum, F. R., Erba, H., Litzow, M. R., Tallman, M. S., Stone, R. M. & Larson, R. A., Apr 4 2019, In : Blood. 133, 14, p. 1548-1559 12 p.

Research output: Contribution to journalArticle

Pediatrics
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Young Adult
Confidence Intervals
Disease-Free Survival
1 Citation (Scopus)

A phase 2, randomized trial evaluating the combination of dalantercept plus axitinib in patients with advanced clear cell renal cell carcinoma

Voss, M. H., Bhatt, R. S., Vogelzang, N. J., Fishman, M., Alter, R. S., Rini, B. I., Beck, J. T., Joshi, M., Hauke, R., Atkins, M. B., Burgess, E., Logan, T. F., Shaffer, D., Parikh, R., Moazzam, N., Zhang, X., Glasser, C., Sherman, M. L. & Plimack, E. R., Jul 15 2019, In : Cancer. 125, 14, p. 2400-2408 9 p.

Research output: Contribution to journalArticle

Renal Cell Carcinoma
Placebos
Disease-Free Survival
axitinib
Human ALK1-Fc fusion protein

A phase I pharmacokinetic study of belinostat in patients with advanced cancers and varying degrees of liver dysfunction

Takebe, N., Beumer, J. H., Kummar, S., Kiesel, B. F., Dowlati, A., O'Sullivan Coyne, G., Piekarz, R., Rubinstein, L., Fogli, L. K., Vaishampayan, U., Goel, S., O'Bryant, C. L., El-Rayes, B. F., Chung, V., Lenz, H. J., Kim, R., Belani, C., Tuscano, J. M., Schelman, W., Moore, N. & 2 others, Doroshow, J. H. & Chen, A. P., Jan 1 2019, (Accepted/In press) In : British Journal of Clinical Pharmacology.

Research output: Contribution to journalArticle

Open Access
Liver Diseases
Pharmacokinetics
Neoplasms
Maximum Tolerated Dose
Liver
2 Citations (Scopus)

A randomized trial of three novel regimens for recurrent acute myeloid leukemia demonstrates the continuing challenge of treating this difficult disease

Litzow, M. R., Wang, X. V., Carroll, M. P., Karp, J. E., Ketterling, R. P., Zhang, Y., Kaufmann, S. H., Lazarus, H. M., Luger, S. M., Paietta, E. M., Pratz, K. W., Tun, H. W., Altman, J. K., Broun, E. R., Rybka, W., Rowe, J. M. & Tallman, M. S., Jan 1 2019, In : American Journal of Hematology. 94, 1, p. 111-117 7 p.

Research output: Contribution to journalArticle

alvocidib
Mitoxantrone
Cytarabine
Acute Myeloid Leukemia
Topotecan

ASR352, A potent anticancer agent: Synthesis, preliminary SAR, and biological activities against colorectal cancer bulk, 5-fluorouracil/oxaliplatin resistant and stem cells

Narayan, S., Ramisetti, S., Jaiswal, A. S., Law, B. K., Singh-Pillay, A., Singh, P., Amin, S. & Sharma, A., Jan 1 2019, In : European Journal of Medicinal Chemistry. 161, p. 456-467 12 p.

Research output: Contribution to journalArticle

oxaliplatin
Bioactivity
Stem cells
Fluorouracil
Antineoplastic Agents

Association of Antiepileptic Medications with Outcomes after Allogeneic Hematopoietic Cell Transplantation with Busulfan/Cyclophosphamide Conditioning

McCune, J. S., Wang, T., Bo-Subait, K., Aljurf, M., Beitinjaneh, A., Bubalo, J., Cahn, J. Y., Cerny, J., Chhabra, S., Cumpston, A., Dupuis, L. L., Lazarus, H. M., Marks, D. I., Maziarz, R. T., Norkin, M., Prestidge, T., Mineishi, S., Krem, M. M., Pasquini, M. & Martin, P. J., Jul 1 2019, In : Biology of Blood and Marrow Transplantation. 25, 7, p. 1424-1431 8 p.

Research output: Contribution to journalArticle

Busulfan
Cell Transplantation
Phenytoin
Anticonvulsants
Cyclophosphamide

A traction force threshold signifies metastatic phenotypic change in multicellular epithelia

Zhang, Y., Shi, X., Zhao, T., Huang, C., Wei, Q., Tang, X., Santy, L. C., Saif, M. T. A. & Zhang, S., Jan 1 2019, In : Soft Matter. 15, 36, p. 7203-7210 8 p.

Research output: Contribution to journalArticle

epithelium
traction
Stiffness
Phase diagrams
thresholds
Shape optimization
Heat flux
Thermal load
Spacecraft
Physics

Augmenting the therapeutic efficacy of adenosine against pancreatic cancer by switching the Akt/p21-dependent senescence to apoptosis

Yang, D., Zhang, Q., Ma, Y., Che, Z., Zhang, W., Wu, M., Wu, L., Liu, F., Chu, Y., Xu, W., McGrath, M., Song, C. & Liu, J., Sep 1 2019, In : EBioMedicine. 47, p. 114-127 14 p.

Research output: Contribution to journalArticle

Open Access
Pancreatic Neoplasms
Adenosine
Apoptosis
Tumors
Therapeutics
4 Citations (Scopus)

Bacterial blood stream infections (BSIs), particularly post-engraftment BSIs, are associated with increased mortality after allogeneic hematopoietic cell transplantation

Ustun, C., Young, J. A. H., Papanicolaou, G. A., Kim, S., Ahn, K. W., Chen, M., Abdel-Azim, H., Aljurf, M., Beitinjaneh, A., Brown, V., Cerny, J., Chhabra, S., Kharfan-Dabaja, M. A., Dahi, P. B., Daly, A., Dandoy, C. E., Dvorak, C. C., Freytes, C. O., Hashmi, S., Lazarus, H. & 13 others, Ljungman, P., Nishihori, T., Page, K., Pingali, S. R. K., Saad, A., Savani, B. N., Weisdorf, D., Williams, K., Wirk, B., Auletta, J. J., Lindemans, C. A., Komanduri, K. & Riches, M., Aug 1 2019, In : Bone Marrow Transplantation. 54, 8, p. 1254-1265 12 p.

Research output: Contribution to journalArticle

Cell Transplantation
Mortality
Infection

Bif-1/Endophilin B1/SH3GLB1 regulates bone homeostasis

Touyama, K., Khan, M., Aoki, K., Matsuda, M., Hiura, F., Takakura, N., Matsubara, T., Harada, Y., Hirohashi, Y., Tamura, Y., Gao, J., Mori, K., Kokabu, S., Yasuda, H., Fujita, Y., Watanabe, K., Takahashi, Y., Maki, K. & Jimi, E., Jan 1 2019, (Accepted/In press) In : Journal of cellular biochemistry.

Research output: Contribution to journalArticle

Bone
Homeostasis
Bone and Bones
Osteoclasts
Osteogenesis

Bif-1 interacts with prohibitin-2 to regulate mitochondrial inner membrane during cell stress and apoptosis

Cho, S. G., Xiao, X., Wang, S., Gao, H., Rafikov, R., Black, S., Huang, S., Ding, H. F., Yoon, Y., Kirken, R. A., Yin, X. M., Wang, H-G. & Dong, Z., Jul 1 2019, In : Journal of the American Society of Nephrology. 30, 7, p. 1174-1191 18 p.

Research output: Contribution to journalArticle

Mitochondrial Membranes
Apoptosis
Proteolysis
Mitochondrial Dynamics
Kidney

Blockade of the OGF-OGFr pathway in diabetic bone

Titunick, M. B., Lewis, G., Cain, J., Zagon, I. & McLaughlin, P., Jan 1 2019, In : Connective Tissue Research. 60, 6, p. 521-529 9 p.

Research output: Contribution to journalArticle

Naltrexone
Opioid Analgesics
Intercellular Signaling Peptides and Proteins
Bone
Bone and Bones
2 Citations (Scopus)

Brain cholesterol metabolism and Parkinson's disease

Huang, X., Sterling, N. W., Du, G., Sun, D., Stetter, C., Kong, L., Zhu, Y., Neighbors, J., Lewis, M., Chen, H., Hohl, R. & Mailman, R., Mar 1 2019, In : Movement Disorders. 34, 3, p. 386-395 10 p.

Research output: Contribution to journalArticle

Parkinson Disease
Cholesterol
Brain
Odds Ratio
Logistic Models
1 Citation (Scopus)

Cardiomyopathy Mutations in Metavinculin Disrupt Regulation of Vinculin-Induced F-Actin Assemblies

Sarker, M., Lee, H. T., Mei, L., Krokhotin, A., de los Reyes, S. E., Yen, L., Costantini, L. M., Griffith, J., Dokholyan, N., Alushin, G. M. & Campbell, S. L., Apr 5 2019, In : Journal of Molecular Biology. 431, 8, p. 1604-1618 15 p.

Research output: Contribution to journalArticle

Vinculin
Cardiomyopathies
Actins
Mutation
Dimerization
2 Citations (Scopus)
Ceruloplasmin
Haptoglobins
Vascular Endothelial Growth Factor A
HIV Infections
Cerebrospinal Fluid

Characteristics of Adult Cigarette Smokers Who "Relight" and the Effects of Exposure to Tobacco Smoke Constituents

Allen, S. I., Wasserman, E., Veldheer, S., Yingst, J., Hrabovsky, S., Liao, J. J., Krebs, N. M., Horn, K., Reinhart, L., Modesto, J., Putt, K., Evins, A. E., Muscat, J., Richie, J. & Foulds, J., Aug 19 2019, In : Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. 21, 9, p. 1206-1212 7 p.

Research output: Contribution to journalArticle

Smoke
Tobacco Products
Tobacco
Tobacco Use Disorder
Cotinine
1 Citation (Scopus)

Characteristics of Late Fatal Infections after Allogeneic Hematopoietic Cell Transplantation

Norkin, M., Shaw, B. E., Brazauskas, R., Tecca, H. R., Leather, H. L., Gea-Banacloche, J., T. Kamble, R., DeFilipp, Z., Jacobsohn, D. A., Ringden, O., Inamoto, Y., A. Kasow, K., Buchbinder, D., Shaw, P., Hematti, P., Schears, R., Badawy, S. M., Lazarus, H. M., Bhatt, N., Horn, B. & 32 others, Chhabra, S., M. Page, K., Hamilton, B., Hildebrandt, G. C., Yared, J. A., Agrawal, V., M. Beitinjaneh, A., Majhail, N., Kindwall-Keller, T., Olsson, R. F., Schoemans, H., Gale, R. P., Ganguly, S., A. Ahmed, I., Schouten, H. C., L. Liesveld, J., Khera, N., Steinberg, A., Shah, A. J., Solh, M., Marks, D. I., Rybka, W., Aljurf, M., Dietz, A. C., Gergis, U., George, B., Seo, S., Flowers, M. E. D., Battiwalla, M., Savani, B. N., Riches, M. L. & Wingard, J. R., Feb 1 2019, In : Biology of Blood and Marrow Transplantation. 25, 2, p. 362-368 7 p.

Research output: Contribution to journalArticle

Cell Transplantation
Infection
Confidence Intervals
Pediatrics
Incidence

Characterization of histone deacetylase expression within in vitro and in vivo bladder cancer model systems

Buckwalter, J. M., Chan, W., Shuman, L., Wildermuth, T., Ellis-Mohl, J., Walter, V., Warrick, J., Wu, X. R., Kaag, M. G., Raman, J. & Degraff, D., May 2 2019, In : International journal of molecular sciences. 20, 10, 2599.

Research output: Contribution to journalArticle

Open Access
Histone Deacetylases
bladder
Polymerase chain reaction
Urinary Bladder Neoplasms
cancer

Chemotherapy selection pressure alters sphingolipid composition and mitochondrial bioenergetics in resistant HL-60 cells

Kao, L. P., Morad, S. A. F., Davis, T. S., MacDougall, M. R., Kassai, M., Abdelmageed, N., Fox, T. E., Kester, M., Loughran, T. P., Abad, J. L., Fabrias, G., Tan, S. F., Feith, D. J., Claxton, D., Spiegel, S., Fisher-Wellman, K. H. & Cabot, M. C., Jan 1 2019, In : Journal of Lipid Research. 60, 9, p. 1590-1602 13 p.

Research output: Contribution to journalArticle

Sphingolipids
Chemotherapy
HL-60 Cells
Cytarabine
Daunorubicin

Chest Tube Drainage Devices

Toth, J., Reed, M. F. & Ventola, L. K., Jan 1 2019, In : Seminars in Respiratory and Critical Care Medicine. 40, 3, p. 386-393 8 p.

Research output: Contribution to journalArticle

Chest Tubes
Drainage
Air
Equipment and Supplies
Vacuum
2 Citations (Scopus)

Chondrocyte mTORC1 activation stimulates miR-483-5p via HDAC4 in osteoarthritis progression

Wang, H., Zhang, H., Sun, Q., Yang, J., Zeng, C., Ding, C., Cai, D., Liu, A. & Bai, X., Mar 1 2019, In : Journal of Cellular Physiology. 234, 3, p. 2730-2740 11 p.

Research output: Contribution to journalArticle

Histone Deacetylases
Chondrocytes
Osteoarthritis
Chemical activation
Hypertrophy

Chronic treatment with multi-kinase inhibitors causes differential toxicities on skeletal and cardiac muscles

Huot, J. R., Essex, A. L., Gutierrez, M., Barreto, R., Wang, M., Waning, D., Plotkin, L. I. & Bonetto, A., Apr 1 2019, In : Cancers. 11, 4, 571.

Research output: Contribution to journalArticle

Open Access
Myocardium
Skeletal Muscle
Phosphotransferases
Muscles
Cachexia

Circulating microRNAs in plasma before and after radical prostatectomy

McDonald, A., Raman, J., Shen, J., Liao, J. J., Pandya, B. & Vira, M. A., Jan 1 2019, (Accepted/In press) In : Urologic Oncology: Seminars and Original Investigations.

Research output: Contribution to journalArticle

Prostatectomy
MicroRNAs
Prostatic Neoplasms
Neoplasm Grading
Prostate-Specific Antigen

Clip Closure Prevents Bleeding After Endoscopic Resection of Large Colon Polyps in a Randomized Trial

Pohl, H., Grimm, I. S., Moyer, M., Hasan, M. K., Pleskow, D., Elmunzer, B. J., Khashab, M. A., Sanaei, O., Al-Kawas, F. H., Gordon, S. R., Mathew, A., Levenick, J., Aslanian, H. R., Antaki, F., von Renteln, D., Crockett, S. D., Rastogi, A., Gill, J. A., Law, R. J., Elias, P. A. & 4 others, Pellise, M., Wallace, M. B., Mackenzie, T. A. & Rex, D. K., Oct 1 2019, In : Gastroenterology. 157, 4, p. 977-984.e3

Research output: Contribution to journalArticle

Polyps
Surgical Instruments
Colon
Hemorrhage
Control Groups

Collagen-infilled 3D printed scaffolds loaded with miR-148b-transfected bone marrow stem cells improve calvarial bone regeneration in rats

Moncal, K. K., Aydin, R. S. T., Abu-Laban, M., Heo, D. N., Rizk, E., Tucker, S. M., Lewis, G., Hayes, D. J. & Ozbolat, I. T., Dec 1 2019, In : Materials Science and Engineering C. 105, 110128.

Research output: Contribution to journalArticle

bone marrow
stem cells
collagens
Scaffolds (biology)
Stem cells

Collective Cell Migration in 3D Epithelial Wound Healing

Xiao, Y., Riahi, R., Torab, P., Zhang, D. D. & Wong, P. K., Jan 1 2019, In : ACS nano.

Research output: Contribution to journalArticle

wound healing
Actins
Ablation
Gene expression
cells

Comparison of enhancement quantification from virtual unenhanced images to true unenhanced images in multiphase renal Dual-Energy computed tomography: A phantom study

Olivia Popnoe, D., Ng, C. S., Zhou, S., Cheenu Kappadath, S., Pan, T. & Kyle Jones, A., Jan 1 2019, In : Journal of applied clinical medical physics. 20, 8, p. 171-179 9 p.

Research output: Contribution to journalArticle

Open Access
Tomography
tomography
Kidney
lesions
augmentation

Conductance-Based Biophysical Distinction and Microfluidic Enrichment of Nanovesicles Derived from Pancreatic Tumor Cells of Varying Invasiveness

Moore, J. H., Varhue, W. B., Su, Y. H., Linton, S. S., Farmehini, V., Fox, T. E., Matters, G., Kester, M. & Swami, N. S., Aug 20 2019, In : Analytical chemistry. 91, 16, p. 10424-10431 8 p.

Research output: Contribution to journalArticle

Microfluidics
Tumors
Cells
Lipids
Fluidity
1 Citation (Scopus)

Conformational ensemble of native α-synuclein in solution as determined by short-distance crosslinking constraint-guided discrete molecular dynamics simulations

Brodie, N. I., Popov, K. I., Petrotchenko, E. V., Dokholyan, N. & Borchers, C. H., Mar 1 2019, In : PLoS computational biology. 15, 3, e1006859.

Research output: Contribution to journalArticle

Open Access
Synucleins
Discrete Dynamics
molecular dynamics
protein structure
Molecular Dynamics Simulation

Conjugated bile acids attenuate allergen-induced airway inflammation and hyperresposiveness by inhibiting UPR transducers

Nakada, E. M., Bhakta, N. R., Korwin-Mihavics, B. R., Kumar, A., Chamberlain, N., Bruno, S. R., Chapman, D. G., Hoffman, S. M., Daphtary, N., Aliyeva, M., Irvin, C. G., Dixon, A. E., Woodruff, P. G., Amin, S., Poynter, M. E., Desai, D. & Anathy, V., Jan 1 2019, In : JCI Insight. 4, 9, e98101.

Research output: Contribution to journalArticle

Open Access
Unfolded Protein Response
Transducers
Bile Acids and Salts
Allergens
Inflammation
3 Citations (Scopus)

Cooperation among cancer cells: applying game theory to cancer

Archetti, M. & Pienta, K. J., Feb 1 2019, In : Nature Reviews Cancer. 19, 2, p. 110-117 8 p.

Research output: Contribution to journalArticle

Game Theory
Neoplasms
Stromal Cells
Research

Correcting errors in the BRCA1 warning system

Liang, Y., Dearnaley, W. J., Alden, N. A., Solares, M. J., Gilmore, B. L., Pridham, K. J., Varano, C., Sheng, Z., Alli, E. & Kelly, D., Jan 1 2019, In : DNA Repair. 73, p. 120-128 9 p.

Research output: Contribution to journalArticle

BRCA1 Protein
Alarm systems
Repair
Biochemical Phenomena
Cells

Cross-talk between N-terminal and C-terminal domains in stromal interaction molecule 2 (STIM2) determines enhanced STIM2 sensitivity

Emrich, S. M., Yoast, R. E., Xin, P., Zhang, X., Pathak, T., Nwokonko, R., Gueguinou, M. F., Subedi, K. P., Zhou, Y., Ambudkar, I. S., Hempel, N., Machaca, K., Gill, D. & Trebak, M., Jan 1 2019, In : Journal of Biological Chemistry. 294, 16, p. 6318-6332 15 p.

Research output: Contribution to journalArticle

Molecules
Chemical activation
Clustered Regularly Interspaced Short Palindromic Repeats
Cell Membrane
Stromal Interaction Molecule 2

Cryo-EM-On-a-Chip: Custom-Designed Substrates for the 3D Analysis of Macromolecules

Alden, N. A., Varano, C., Dearnaley, W. J., Solares, M. J., Luqiu, W. Y., Liang, Y., Sheng, Z., McDonald, S. M., Damiano, J., McConnell, J., Dukes, M. J. & Kelly, D., May 24 2019, In : Small. 15, 21, 1900918.

Research output: Contribution to journalArticle

Cryoelectron Microscopy
Macromolecules
Electron microscopy
Tumors
Cells

Cryo-EM Reveals Architectural Diversity in Active Rotavirus Particles

Hauser, M., Dearnaley, W. J., Varano, C., Casasanta, M., McDonald, S. M. & Kelly, D., Jan 1 2019, In : Computational and Structural Biotechnology Journal. 17, p. 1178-1183 6 p.

Research output: Contribution to journalArticle

Open Access
Rotavirus
Transcription
RNA
Proteins
Messenger RNA
1 Citation (Scopus)

Decreasing Wound Edge Stress Enhances Leader Cell Formation during Collective Smooth Muscle Cell Migration

Dean, Z. S., Jamilpour, N., Slepian, M. J. & Wong, P. K., Aug 12 2019, In : ACS Biomaterials Science and Engineering. 5, 8, p. 3864-3875 12 p.

Research output: Contribution to journalArticle

Muscle
Cells
Repair
Gene expression
Microscopic examination

Dendritic Cell Regulation of Graft Vs.-Host Disease: Immunostimulation and Tolerance Immunostimulation

Yu, H., Tian, Y., Wang, Y., Mineishi, S. & Zhang, Y., Jan 1 2019, In : Frontiers in immunology. 10, FEB, 93.

Research output: Contribution to journalArticle

Open Access
Dendritic Cells
Immunization
Transplants
Hematopoietic Stem Cells
Hematopoietic Stem Cell Transplantation