Research Output 1965 2019

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(Not giving up) the marathon race of Met targeting therapy: Are we there yet?

Ma, P. C-C., Apr 15 2019, In : Clinical Cancer Research. 25, 8, p. 2375-2378 4 p.

Research output: Contribution to journalArticle

Biomarkers
Therapeutics
21 Citations (Scopus)

[2+2] versus [4+2] cycloaddition reactions of 1,3-diaza-1,3-butadienes with various mono- and disubstituted ketenes and supporting mechanistic considerations

Mukherjee, S., Mazumdar, S. N., Sharma, A. & Mahajan, M. P., Dec 1 1998, In : Heterocycles. 47, 2, p. 933-950 18 p.

Research output: Contribution to journalArticle

Cycloaddition
Cycloaddition Reaction
Electrons
1,3-butadiene
ketene
101 Citations (Scopus)

[21] Construction of High Copy Yeast Vectors Using 2-μm Circle Sequences

Broach, J., Jan 1 1983, In : Methods in enzymology. 101, C, p. 307-325 19 p.

Research output: Contribution to journalArticle

Fungal DNA
Genetic engineering
Genetic Vectors
DNA Restriction Enzymes
Yeast
2 Citations (Scopus)

[3H]naloxone binding in the brains of young rats perinatally exposed to methadone

Zagon, I., Kirby, M. L., McLaughlin, P. & Stewart, D. E., Jan 1 1984, In : Research Communications in Substances of Abuse. 5, 1, p. 51-59 9 p.

Research output: Contribution to journalArticle

Methadone
Naloxone
Opioid Receptors
Brain
Levorphanol
17 Citations (Scopus)
Collagen Type IV
Integrins
Cell Movement
Thapsigargin
Ionophores
1 Citation (Scopus)

[Diminished expression of CD5 and/or CD7 surface antigens as the first clue of diagnosis for monoclonal T lymphocytosis].

Kawano, H., Minagawa, K., Wakahashi, K., Kawano, Y., Sada, A., Matsui, T. & Katayama, Y., Jan 1 2012, In : [Rinshō ketsueki] The Japanese journal of clinical hematology. 53, 8, p. 785-787 3 p.

Research output: Contribution to journalArticle

CD7 Antigens
Lymphocytosis
Surface Antigens
T-Lymphocytes
Leukocytosis

[Thrombopoietin receptor agonists administration for acute exacerbation of chronic idiopathic thrombocytopenic purpura and subsequent anticoagulant therapy for accompanying deep venous thrombosis of the lower limbs].

Kawano, H., Suzuki, T., Ishii, S., Wakahashi, K., Kawano, Y., Sada, A., Minagawa, K., Takaya, T., Yamashita, T., Hirata, K. I., Koriyama, K., Nagamatsu, Y., Matsui, T. & Katayama, Y., Jan 1 2014, In : [Rinshō ketsueki] The Japanese journal of clinical hematology. 55, 6, p. 697-702 6 p.

Research output: Contribution to journalArticle

Thrombopoietin Receptors
Idiopathic Thrombocytopenic Purpura
Venous Thrombosis
Anticoagulants
Lower Extremity
21 Citations (Scopus)

1,2,3,4,6-penta-o-galloly-beta-D-glucose suppresses hypoxia-induced accumulation of hypoxia-inducible factor-1α and signaling in LNCaP prostate cancer cells

Park, K. Y., Lee, H. J., Jeong, S. J., Lee, H. J., Kim, H. S., Kim, S. H., Lim, S., Kim, H. C., Lu, J. & Kim, S. H., Nov 19 2010, In : Biological and Pharmaceutical Bulletin. 33, 11, p. 1835-1840 6 p.

Research output: Contribution to journalArticle

Hypoxia-Inducible Factor 1
Rubiaceae
Prostatic Neoplasms
Glucose
1-Phosphatidylinositol 4-Kinase

10th World Conference on Lung Cancer, Vancouver, British Columbia, Canada

Klem, J., Maung, K., Lee, D., Tyagi, P., Belani, C. & Ramalingam, S., Jan 1 2003, In : Clinical Lung Cancer. 5, 3, p. 142-147 6 p.

Research output: Contribution to journalArticle

Antineoplastic Combined Chemotherapy Protocols
Quinazolines
Taxoids
Deoxycytidine
British Columbia

10th World Congress on Lung Cancer, Vancouver, British Columbia, Canada

Tyagi, P., Lee, D., Belani, C. & Ramalingam, S., Jan 1 2003, In : Clinical Lung Cancer. 5, 2, p. 78-82 5 p.

Research output: Contribution to journalArticle

Antineoplastic Combined Chemotherapy Protocols
Emission-Computed Tomography
British Columbia
Survival Analysis
Non-Small Cell Lung Carcinoma
45 Citations (Scopus)

11H-Isoquino[4,3-c]cinnolin-12-ones: Novel anticancer agents with potent topoisomerase I-targeting activity and cytotoxicity

Ruchelman, A. L., Singh, S. K., Ray, A., Wu, X., Yang, J-M., Zhou, N., Liu, A., Liu, L. F. & LaVoie, E. J., Feb 15 2004, In : Bioorganic and Medicinal Chemistry. 12, 4, p. 795-806 12 p.

Research output: Contribution to journalArticle

Type I DNA Topoisomerase
Cytotoxicity
Nude Mice
Antineoplastic Agents
Tumors

14th EORTC-NCI-AACR symposium on molecular targets and cancer Therapeutics, Frankfurt, Germany

Hightower, M., Klem, J., Socinski, M., Belani, C. & Jain, V. K., Jan 1 2003, In : Clinical Lung Cancer. 4, 6, p. 333-335 3 p.

Research output: Contribution to journalArticle

Germany
Neoplasms
Therapeutics
75 Citations (Scopus)
Thioredoxins
Cyclic GMP
Estrogen Receptors
Estradiol
Oxidative stress
68 Citations (Scopus)

1 H and 15 N Magnetic Resonance Assignments, Secondary Structure, and Tertiary Fold of Escherichia coli DnaJ(1-78)

Hill, R. B., Prestegard, J. H. & Flanagan, J., Apr 1 1995, In : Biochemistry. 34, 16, p. 5587-5596 10 p.

Research output: Contribution to journalArticle

Magnetic resonance
Amides
Escherichia coli
Magnetic Resonance Spectroscopy
Nuclear magnetic resonance
93 Citations (Scopus)

2', 2'-difluorodeoxycytidine metabolism and mechanism of action in human leukemia cells

Plunkett, W., Gandhi, V., Chubb, S., Nowak, B., Heinemann, V., Mineishi, S. & Sen, A., Jan 1 1989, In : Nucleosides and Nucleotides. 8, 5-6, p. 775-785 11 p.

Research output: Contribution to journalArticle

gemcitabine
Metabolism
Leukemia
Ribonucleotide Reductases
DNA
18 Citations (Scopus)

2-(Acyloxy)ethylphosphonate analogues of prenyl pyrophosphates: synthesis and biological characterization

Cermak, D. M., Wiemer, D. F., Lewis, K. & Hohl, R., Nov 27 2000, In : Bioorganic and Medicinal Chemistry. 8, 12, p. 2729-2737 9 p.

Research output: Contribution to journalArticle

Organophosphonates
Diphosphates
Phosphorous Acids
Esters
Bearings (structural)

2004 Highlights from: 29th European Society of Medical Oncology Congress. Vienna, Austria. October 29 through November 2, 2004

Reddy, G. K. & Belani, C., Jan 1 2005, In : Clinical Lung Cancer. 6, 5, p. 272-275 4 p.

Research output: Contribution to journalArticle

Medical Oncology
Austria

27th Congress of the European Society for Medical Oncology. Nice, France

DeGrendele, H., Belani, C. & Jain, V. K., Jan 1 2003, In : Clinical Lung Cancer. 4, 4, p. 205-209 5 p.

Research output: Contribution to journalArticle

France
10 Citations (Scopus)

2-Amino-4-methyl-5-phenylethyl substituted-7-N-benzyl-pyrrolo[2,3-d] pyrimidines as novel antitumor antimitotic agents that also reverse tumor resistance

Gangjee, A., Namjoshi, O. A., Keller, S. N. & Smith, C. D., Jul 15 2011, In : Bioorganic and Medicinal Chemistry. 19, 14, p. 4355-4365 11 p.

Research output: Contribution to journalArticle

Antimitotic Agents
P-Glycoprotein
Antineoplastic Agents
Tumors
Cells
44 Citations (Scopus)

2-Anilino-4-aryl-1,3-thiazole inhibitors of valosin-containing protein (VCP or p97)

Bursavich, M. G., Parker, D. P., Willardsen, J. A., Gao, Z., Davis, T., Ostanin, K., Robinson, R., Peterson, A., Cimbora, D. M., Zhu, J. F. & Richards, B., Mar 1 2010, In : Bioorganic and Medicinal Chemistry Letters. 20, 5, p. 1677-1679 3 p.

Research output: Contribution to journalArticle

Thiazoles
NF-kappa B
Enzyme Inhibitors
Ubiquitin
Proteolysis
12 Citations (Scopus)

2-Deoxy-D-glucose produces delayed hypophagia and conditioned taste aversion in rats

Thompson, C. I. & Zagon, I., Jan 1 1981, In : Physiology and Behavior. 27, 6, p. 1001-1004 4 p.

Research output: Contribution to journalArticle

Deoxyglucose
Saccharin
Eating
Injections
Pharmaceutical Preparations

39th Annual Meeting of the American Society of Clinical Oncology Chicago, Illinois

Lee, D., DeGrendelle, H., Pass, H. & Belani, C., Jan 1 2003, In : Clinical Lung Cancer. 5, 1, p. 13-17 5 p.

Research output: Contribution to journalArticle

64 Citations (Scopus)

3D CT-Video Fusion for Image-Guided Bronchoscopy

Higgins, W. E., Helferty, J. P., Lu, K., Merritt, S. A., Rai, L. & Yu, K. C., Jan 1 2008, In : Computerized Medical Imaging and Graphics. 32, 3, p. 159-173 15 p.

Research output: Contribution to journalArticle

Bronchoscopy
Tomography
Fusion reactions
Physicians
Biopsy
4 Citations (Scopus)

3-Deoxyschweinfurthin B Lowers Cholesterol Levels by Decreasing Synthesis and Increasing Export in Cultured Cancer Cell Lines

Kuder, C. H., Weivoda, M. M., Zhang, Y., Zhu, J., Neighbors, J., Wiemer, D. F. & Hohl, R., Dec 1 2015, In : Lipids. 50, 12, p. 1195-1207 13 p.

Research output: Contribution to journalArticle

Cultured Cells
Cholesterol
Cells
Cell Line
Liver
18 Citations (Scopus)

3D human airway segmentation for virtual bronchoscopy

Kiraly, A. P., Higgins, W. E., Higgins, W. E., Hoffman, E. A., McLennan, G. & Reinhardt, J. M., Jan 1 2002, In : Proceedings of SPIE-The International Society for Optical Engineering. 4683, p. 16-29 14 p.

Research output: Contribution to journalArticle

Segmentation
operators
Hybrid Approach
Region Growing
Operator
35 Citations (Scopus)

3D MDCT-based system for planning peripheral bronchoscopic procedures

Gibbs, J. D., Graham, M. W. & Higgins, W. E., Mar 1 2009, In : Computers in Biology and Medicine. 39, 3, p. 266-279 14 p.

Research output: Contribution to journalArticle

Multidetector computed tomography
Multidetector Computed Tomography
Thorax
Bronchoscopy
Planning
288 Citations (Scopus)

3D microfilter device for viable circulating tumor cell (CTC) enrichment from blood

Zheng, S., Lin, H. K., Lu, B., Williams, A., Datar, R., Cote, R. J. & Tai, Y. C., Feb 1 2011, In : Biomedical Microdevices. 13, 1, p. 203-213 11 p.

Research output: Contribution to journalArticle

Circulating Neoplastic Cells
Tumors
Blood
Cells
Equipment and Supplies

3D numerical study of tumor blood perfusion and oxygen transport during vascular normalization

Wu, J., Cai, Y., Fu, Y., Tan, Z., Sun, R., Xu, S., Ding, Z. & Dong, C., Jan 1 2015, In : Applied Mathematics and Mechanics (English Edition). 36, 2, p. 153-162 10 p.

Research output: Contribution to journalArticle

Normalization
Blood
Tumors
Oxygen
Numerical Study
2 Citations (Scopus)

3D numerical study of tumor microenvironmental flow in response to vascular-disrupting treatments

Wu, J., Cai, Y., Xu, S., Long, Q., Ding, Z. & Dong, C., Aug 24 2012, In : MCB Molecular and Cellular Biomechanics. 9, 2, p. 95-125 31 p.

Research output: Contribution to journalArticle

Blood Vessels
Neoplasms
Microvessels
Tumor Microenvironment
Hemodynamics
36 Citations (Scopus)

3D Printing of Personalized Artificial Bone Scaffolds

Jariwala, S. H., Lewis, G., Bushman, Z. J., Adair, J. H. & Donahue, H. J., Jun 1 2015, In : 3D Printing and Additive Manufacturing. 2, 2, p. 56-64 9 p.

Research output: Contribution to journalArticle

Scaffolds
Printing
Bone
3D printers
Grafts
6 Citations (Scopus)

3D printing of poly(ϵ-caprolactone)/poly(D,L-lactide-co-glycolide)/hydroxyapatite composite constructs for bone tissue engineering

Moncal, K. K., Heo, D. N., Godzik, K. P., Sosnoski, D. M., Mrowczynski, O. D., Rizk, E., Ozbolat, V., Tucker, S. M., Gerhard, E. M., Dey, M., Lewis, G., Yang, J. & Ozbolat, I. T., Jul 27 2018, In : Journal of Materials Research. 33, 14, p. 1972-1986 15 p.

Research output: Contribution to journalArticle

tissue engineering
Durapatite
Hydroxyapatite
Tissue engineering
printing
28 Citations (Scopus)

3D-Printing Strong High-Resolution Antioxidant Bioresorbable Vascular Stents

van Lith, R., Baker, E., Ware, H., Yang, J., Farsheed, A. C., Sun, C. & Ameer, G., Jan 1 2016, In : Advanced Materials Technologies. 1, 9, 1600138.

Research output: Contribution to journalArticle

3D printers
Stents
Antioxidants
Curing
Printing

40th Annual Meeting of the American Society of Clinical Oncology, New Orleans, LA

Price, N., Reddy, G. K. & Belani, C., Jan 1 2004, In : Clinical Lung Cancer. 6, 1, p. 11-16 6 p.

Research output: Contribution to journalArticle

Quinazolines
Medical Societies
Ethnic Groups
Epidermal Growth Factor Receptor
Non-Small Cell Lung Carcinoma
1 Citation (Scopus)

44-homooligomycin e, a new cytotoxic macrolide antibiotic from streptomyces ostreogriseus

Kim, H. S., Bang, H. J., Lee, S., Yoo, O. J., Yoo, J. C., Kim, Y. H. & Lee, J. J., Jan 1 1997, In : Bioscience, Biotechnology and Biochemistry. 61, 2, p. 378-380 3 p.

Research output: Contribution to journalArticle

Antineoplastic Antibiotics
Macrolides
Streptomyces
Cytotoxicity
Tumor Cell Line
86 Citations (Scopus)

5H-Dibenzo[c,h]1,6-naphthyridin-6-ones: Novel topoisomerase I-targeting anticancer agents with potent cytotoxic activity

Ruchelman, A. L., Singh, S. K., Ray, A., Wu, X. H., Yang, J-M., Li, T. K., Liu, A., Liu, L. F. & LaVoie, E. J., May 1 2003, In : Bioorganic and Medicinal Chemistry. 11, 9, p. 2061-2073 13 p.

Research output: Contribution to journalArticle

Naphthyridines
Type I DNA Topoisomerase
Antineoplastic Agents
Tumors
Nude Mice
4 Citations (Scopus)

5′/ 3′ imbalance strategy to detect ALK fusion genes in circulating tumor RNA from patients with non-small cell lung cancer

Tong, Y., Zhao, Z., Liu, B., Bao, A., Zheng, H., Gu, J., McGrath, M., Xia, Y., Tan, B., Song, C. & Li, Y., Mar 27 2018, In : Journal of Experimental and Clinical Cancer Research. 37, 1, 68.

Research output: Contribution to journalArticle

Gene Fusion
Non-Small Cell Lung Carcinoma
RNA
Neoplasms
Sensitivity and Specificity
23 Citations (Scopus)

6-(1-Oxobutyl)-5,8-dimethoxy-1,4-naphthoquinone inhibits Lewis lung cancer by antiangiogenesis and apoptosis

Hyo, J. L., Lee, H. J., Song, G. Y., Li, G., Lee, J. H., Lu, J. & Kim, S. H., Jun 1 2007, In : International Journal of Cancer. 120, 11, p. 2481-2490 10 p.

Research output: Contribution to journalArticle

Lung Neoplasms
Apoptosis
Lewis Lung Carcinoma
Vascular Endothelial Growth Factor A
Neoplasms
36 Citations (Scopus)

7 Å projection map of the S-layer protein sbpA obtained with trehalose-embedded monolayer crystals

Norville, J. E., Kelly, D., Knight, T. F., Belcher, A. M. & Walz, T., Dec 1 2007, In : Journal of Structural Biology. 160, 3, p. 313-323 11 p.

Research output: Contribution to journalArticle

Trehalose
Lipids
Electron Microscopy
Protein Array Analysis
Nanotechnology
1572 Citations (Scopus)

8-Hydroxyguanine, an abundant form of oxidative DNA damage, causes G → T and A → C substitutions

Cheng, K., Cahill, D. S., Kasai, H., Nishimura, S. & Loeb, L. A., Jan 1 1992, In : Journal of Biological Chemistry. 267, 1, p. 166-172 7 p.

Research output: Contribution to journalArticle

DNA Damage
Substitution reactions
Assays
Mutation
DNA
130 Citations (Scopus)

A1, a Bcl-2 family member, prolongs cell survival and permits myeloid differentiation

Lin, E. Y., Orlofsky, A., Wang, H. G., Reed, J. C. & Prystowsky, M. B., Feb 1 1996, In : Blood. 87, 3, p. 983-992 10 p.

Research output: Contribution to journalArticle

Interleukin-3
Cell Survival
Cells
Myeloid Cells
Transfection
15 Citations (Scopus)

A BAC transgenic reporter recapitulates in vivo regulation of human telomerase reverse transcriptase in development and tumorigenesis

Jia, W., Wang, S., Horner, J. W., Wang, N., Wang, H., Gunther, E., De Pinho, R. A. & Zhu, J., Mar 1 2011, In : FASEB Journal. 25, 3, p. 979-989 11 p.

Research output: Contribution to journalArticle

Bacterial Artificial Chromosomes
Chromosomes
Renilla Luciferases
Transcription
Carcinogenesis
3 Citations (Scopus)

ABC294640, A novel sphingosine kinase 2 inhibitor, induces oncogenic virus–infected cell autophagic death and represses tumor growth

Dai, L., Bai, A., Smith, C., Rodriguez, P. C., Yu, F. & Qin, Z., Dec 1 2017, In : Molecular cancer therapeutics. 16, 12, p. 2724-2734 11 p.

Research output: Contribution to journalArticle

Autophagy
Primary Effusion Lymphoma
Viruses
Growth
Sphingolipids
1 Citation (Scopus)

Abdominal pain in a 71-year-old woman

Finstein, J. L., Fox, E., Chin, K. & Alvandi, F., Jan 1 2006, In : Clinical Orthopaedics and Related Research. 453, p. 341-347 7 p.

Research output: Contribution to journalArticle

Spinal Neoplasms
Thoracic Vertebrae
Ewing's Sarcoma
Abdominal Pain
Differential Diagnosis
3 Citations (Scopus)

Aberrant ARID5B expression and its association with Ikaros dysfunction in acute lymphoblastic leukemia

Ge, Z., Han, Q., Gu, Y., Ge, Q., Ma, J., Sloane, J., Gao, G., Payne, K. J., Szekely, L., Song, C. & Dovat, S., Nov 1 2018, In : Oncogenesis. 7, 11, 84.

Research output: Contribution to journalArticle

Precursor Cell Lymphoblastic Leukemia-Lymphoma
Fingers
Cell Proliferation
Protein Domains
Casein Kinase II
1082 Citations (Scopus)

Aberrant CpG-island methylation has non-random and tumour-type-specific patterns

Costello, J. F., Frühwald, M. C., Smiraglia, D. J., Rush, L. J., Robertson, G., Gao, X., Wright, F. A., Feramisco, J. D., Peltomäki, P., Lang, J. C., Schuller, D. E., Yu, L., Bloomfield, C. D., Caligiuri, M. A., Yates, A., Nishikawa, R., Su Huang, H. J., Petrelli, N. J., Zhang, X., O'Dorisio, M. S. & 3 others, Held, W. A., Cavenee, W. K. & Plass, C., Feb 1 2000, In : Nature Genetics. 24, 2, p. 132-138 7 p.

Research output: Contribution to journalArticle

CpG Islands
Methylation
Neoplasms
Genome
Cultured Tumor Cells
14 Citations (Scopus)

Aberrant over-expression of TRPM7 ion channels in pancreatic cancer: Required for cancer cell invasion and implicated in tumor growth and metastasis

Yee, N. S-S., Kazi, A., Li, Q., Yang, Z., Berg, A. & Yee, R. K., Jan 1 2015, In : Biology Open. 4, 4, p. 507-514 8 p.

Research output: Contribution to journalArticle

pancreatic neoplasms
cell invasion
ion channels
Pancreatic Neoplasms
Ion Channels
2 Citations (Scopus)

Aberrations in the iron regulatory gene signature are associated with decreased survival in diffuse infiltrating gliomas

Weston, C., Klobusicky, J., Weston, J., Connor, J., Toms, S. A. & Marko, N. F., Nov 1 2016, In : PloS one. 11, 11, e0166593.

Research output: Contribution to journalArticle

Regulator Genes
Iron-Regulatory Proteins
regulator genes
Aberrations
Glioma
184 Citations (Scopus)

Ab Initio Folding of Proteins with All-Atom Discrete Molecular Dynamics

Ding, F., Tsao, D., Nie, H. & Dokholyan, N., Jul 9 2008, In : Structure. 16, 7, p. 1010-1018 9 p.

Research output: Contribution to journalArticle

Protein Folding
Molecular Dynamics Simulation
Proteins
Hydrogen
Protein Engineering
172 Citations (Scopus)

Ab initio RNA folding by discrete molecular dynamics: From structure prediction to folding mechanisms

Ding, F., Sharma, S., Chalasani, P., Demidov, V. V., Broude, N. E. & Dokholyan, N., Jun 1 2008, In : RNA. 14, 6, p. 1164-1173 10 p.

Research output: Contribution to journalArticle

RNA Folding
Molecular Dynamics Simulation
RNA
Base Pairing
RNA, Transfer, Phe
55 Citations (Scopus)

A biosensor platform for rapid antimicrobial susceptibility testing directly from clinical samples

MacH, K. E., Mohan, R., Baron, E. J., Shih, M. C., Gau, V., Wong, P. K. & Liao, J. C., Jan 1 2011, In : Journal of Urology. 185, 1, p. 148-153 6 p.

Research output: Contribution to journalArticle

Biosensing Techniques
Anti-Bacterial Agents
Point-of-Care Systems
Urine
Growth