Cancer Institute, Experimental Therapeutics

  • United States

Research Output 1965 2020

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13 Citations (Scopus)

An Analysis of Oncotype DX Recurrence Scores and Clinicopathologic Characteristics in Invasive Lobular Breast Cancer

Felts, J. L., Zhu, J., Han, B., Smith, J. S. & Truica, C., Nov 1 2017, In : Breast Journal. 23, 6, p. 677-686 10 p.

Research output: Contribution to journal › Article

Lobular Carcinoma
Ductal Carcinoma
Breast Neoplasms
Recurrence
Sequoia
6 Citations (Scopus)

A nanobiosensor for dynamic single cell analysis during microvascular self-organization

Wang, S., Sun, J., Zhang, D. D. & Wong, P. K., Oct 14 2016, In : Nanoscale. 8, 38, p. 16894-16901 8 p.

Research output: Contribution to journal › Article

Messenger RNA
Endothelial cells
RNA
Tissue engineering
Gene expression
12 Citations (Scopus)

A Nanostructured Microfluidic Immunoassay Platform for Highly Sensitive Infectious Pathogen Detection

Yu, X., Xia, Y., Tang, Y., Zhang, W. L., Yeh, Y-T., Lu, H. & Zheng, S., Jun 27 2017, In : Small. 13, 24, 1700425.

Research output: Contribution to journal › Article

Nanotubes
Influenza in Birds
Microfluidics
Pathogens
Orthomyxoviridae
9 Citations (Scopus)

An assessment of musculoskeletal knowledge in graduating medical and physician assistant students and implications for musculoskeletal care providers

Grunfeld, R., Banks, S., Fox, E., Levy, B. A., Craig, C. & Black, K., Feb 15 2012, In : Journal of Bone and Joint Surgery - Series A. 94, 4, p. 343-348 6 p.

Research output: Contribution to journal › Article

Physician Assistants
Students
Medical Students
Coroners and Medical Examiners
Orthopedics
23 Citations (Scopus)

An autophagy assay reveals the ESCRT-III component CHMP2A as a regulator of phagophore closure

Takahashi, Y., He, H., Tang, Z., Hattori, T., Liu, Y., Young, M. M., Serfass, J. M., Chen, L., Gebru, M., Chen, C., Wills, C. A., Atkinson, J. M., Chen, H., Abraham, T. & Wang, H-G., Dec 1 2018, In : Nature communications. 9, 1, 2855.

Research output: Contribution to journal › Article

Endosomal Sorting Complexes Required for Transport
regulators
Autophagy
classifying
closures
104 Citations (Scopus)

An AUTS2-Polycomb complex activates gene expression in the CNS

Gao, Z., Lee, P., Stafford, J. M., Schimmelmann, M. V., Schaefer, A. & Reinberg, D., Dec 18 2014, In : Nature. 516, 7531, p. 349-354 6 p.

Research output: Contribution to journal › Article

Polycomb Repressive Complex 1
Autistic Disorder
Central Nervous System
Gene Expression
Polycomb-Group Proteins
3 Citations (Scopus)

Androgen mediated translational and postranslational regulation of IGFBP-2 in androgen-sensitive LNCAP human prostate cancer cells

DeGraff, D. J., Aguiar, A. A., Chen, Q., Adams, L. K., Williams, B. J. & Sikes, R. A., Jun 4 2010, In : American Journal of Translational Research. 2, 2, p. 200-208 9 p.

Research output: Contribution to journal › Article

Insulin-Like Growth Factor Binding Protein 2
Androgens
Prostatic Neoplasms
Cells
Messenger RNA
29 Citations (Scopus)

Androgen receptor-dependent regulation of Bcl-xL expression: Implication in prostate cancer progression

Sun, A., Tang, J., Hong, Y., Song, J., Terranova, P. F., Thrasher, J. B., Svojanovsky, S., Wang, H. G. & Li, B., Mar 1 2008, In : Prostate. 68, 4, p. 453-461 9 p.

Research output: Contribution to journal › Article

Androgen Receptors
Prostatic Neoplasms
Androgens
Castration
Cell Proliferation
48 Citations (Scopus)

An effective network reduction approach to find the dynamical repertoire of discrete dynamic networks

Zañudo, J. G. T. & Albert, R., Jan 1 2013, In : Chaos. 23, 2, 025111.

Research output: Contribution to journal › Article

Discrete Dynamics
Dynamic Networks
T-cells
Dynamic models
Attractor
6 Citations (Scopus)

An Electrochemical Biosensor for Rapid Detection of Pediatric Bloodstream Infections

Kurundu Hewage, E. M. K., Spear, D., Umstead, T. M., Hu, S., Wang, M., Wong, P. K., Chroneos, Z., Halstead, E. S. & Thomas, N., Dec 1 2017, In : SLAS Technology. 22, 6, p. 616-625 10 p.

Research output: Contribution to journal › Article

Pediatrics
Biosensing Techniques
Biosensors
Blood
Infection
3 Citations (Scopus)

An electrophoretic mobility study of uric acid with special reference to kidney stone formation

Adair, J. H., Aylmore, L. A. G., Brockis, J. G. & Bowyer, R. C., Jul 1988, In : Journal of Colloid And Interface Science. 124, 1, p. 1-13 13 p.

Research output: Contribution to journal › Article

Electrophoretic mobility
Uric Acid
Acids
Colloids
Surface charge
14 Citations (Scopus)

An empirical Bayes approach to smoothing in backcalculation of HIV infection rates

Liao, J. & Brookmeyer, R., Aug 8 1995, In : Biometrics. 51, 2, p. 579-588 10 p.

Research output: Contribution to journal › Article

Empirical Bayes
HIV infections
Deconvolution
Virus Diseases
Viruses

An endogenous opioid system is present and modulates dna synthesis during fetal rat development

McLaughlin, P., Wu, Y. & Zaeon, I. S., 1996, In : FASEB Journal. 10, 3

Research output: Contribution to journal › Article

Naltrexone
narcotics
Carbon Monoxide
Fetal Development
Opioid Analgesics
60 Citations (Scopus)

An essential role of NRF2 in diabetic wound healing

Long, M., De La Vega, M. R., Wen, Q., Bharara, M., Jiang, T., Zhang, R., Zhou, S., Wong, P. K., Wondrak, G. T., Zheng, H. & Zhang, D. D., Mar 1 2016, In : Diabetes. 65, 3, p. 780-793 14 p.

Research output: Contribution to journal › Article

NF-E2-Related Factor 2
Wound Healing
Skin Ulcer
Matrix Metalloproteinase 9
Transforming Growth Factors
39 Citations (Scopus)

An etoposide-resistant lung cancer subline overexpresses the multidrug resistance-associated protein

Doyle, L. A., Ross, D. D., Ordonez, J. V., Yang, W., Gao, Y., Tong, Y., Belani, C. & Gutheil, J. C., Jan 1 1995, In : British Journal of Cancer. 72, 3, p. 535-542 8 p.

Research output: Contribution to journal › Article

Viral Structural Proteins
Multidrug Resistance-Associated Proteins
Etoposide
Lung Neoplasms
Daunorubicin
55 Citations (Scopus)

A network model for plant-pollinator community assembly

Campbell, C., Yang, S., Albert, R. Z. & Shea, K., Jan 4 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 1, p. 197-202 6 p.

Research output: Contribution to journal › Article

Food Chain
Biota
Biodiversity
14 Citations (Scopus)

An evaluation of the mutagenicity, metabolism, and DNA adduct formation of 5-nitrobenzo [b] naphtho [2,1-d] thiophene

King, L. C., Kohan, M. J., Brooks, L., Nelson, G. B., Ross, J. A., Allison, J., Adams, L., Desai, D., Amin, S., Padgett, W., Lambert, G. R., Richard, A. M. & Nesnow, S., Jul 4 2001, In : Chemical research in toxicology. 14, 6, p. 661-671 11 p.

Research output: Contribution to journal › Article

Thiophenes
DNA Adducts
Metabolism
Xanthine Oxidase
Deoxyguanosine
10 Citations (Scopus)

An evolutionary perspective: using the comparative method

Harvey, P. H., Read, A. F., John, J. L., Gregory, R. D. & Keymer, A. E., Jan 1 1991, In : Unknown Journal. p. 344-355 12 p.

Research output: Contribution to journal › Article

parasite
parasite prevalence
sexual selection
method
indicator
105 Citations (Scopus)

A new biodegradable polyester elastomer for cartilage tissue engineering

Kang, Y., Yang, J., Khan, S., Anissian, L. & Ameer, G. A., May 1 2006, In : Journal of Biomedical Materials Research - Part A. 77, 2, p. 331-339 9 p.

Research output: Contribution to journal › Article

Elastomers
Polyesters
Cartilage
Tissue engineering
Scaffolds
14 Citations (Scopus)

A new chalcone derivative (E)-3-(4-methoxyphenyl)-2-methyl-1-(3,4,5- trimethoxyphenyl)prop-2-en-1-one Suppresses prostate cancer involving p53-mediated cell cycle arrests and apoptosis

Zhang, Y., Srinivasan, B., Xing, C. & Lu, J., Sep 1 2012, In : Anticancer Research. 32, 9, p. 3689-3698 10 p.

Research output: Contribution to journal › Article

Chalcone
Cell Cycle Checkpoints
Prostatic Neoplasms
Apoptosis
Growth
14 Citations (Scopus)

A new discrete dynamic model of ABA-induced stomatal closure predicts key feedback loops

Albert, R., Acharya, B. R., Jeon, B. W., Zañudo, J. G. T., Zhu, M., Osman, K. & Assmann, S. M., Sep 22 2017, In : PLoS biology. 15, 9, e2003451.

Research output: Contribution to journal › Article

Abscisic Acid
dynamic models
abscisic acid
Dynamic models
Feedback
29 Citations (Scopus)

A new generation of sodium chloride porogen for tissue engineering

Tran, R. T., Naseri, E., Kolasnikov, A., Bai, X. & Yang, J., Sep 1 2011, In : Biotechnology and Applied Biochemistry. 58, 5, p. 335-344 10 p.

Research output: Contribution to journal › Article

Sodium chloride
Tissue Engineering
Crystallization
Tissue engineering
Sodium Chloride
13 Citations (Scopus)

A new non-randomized multi-category response model for surveys with a single sensitive question: Design and analysis

Tang, M. L., Tian, G. L., Tang, N. S. & Liu, Z., Dec 1 2009, In : Journal of the Korean Statistical Society. 38, 4, p. 339-349 11 p.

Research output: Contribution to journal › Article

Maximum Likelihood Estimate
Confidence interval
Multiple Outcomes
Randomized Response
Data Augmentation
12 Citations (Scopus)

A new strategy to characterize the extent of reaction of thermoset elastomers

Webb, A. R., Yang, J. & Ameer, G. A., Feb 15 2008, In : Journal of Polymer Science, Part A: Polymer Chemistry. 46, 4, p. 1318-1328 11 p.

Research output: Contribution to journal › Article

Elastomers
Thermosets
Molecular weight
Dynamic mechanical analysis
Gelation
1 Citation (Scopus)

An experimental study of the fluctuations in granular drag

Albert, I., Tegzes, P., Albert, R., Sample, J., Barabási, A. L., Vicsek, T., Kahng, B. & Schiffer, P., Jan 1 2000, In : Materials Research Society Symposium - Proceedings. 627, p. BB771-BB776

Research output: Contribution to journal › Article

Stick-slip
Jamming
drag
Drag
jamming
15 Citations (Scopus)

Angiogenesis and survival in patients with myelodysplastic syndrome

Savic, A., Cemerikic-Martinovic, V., Dovat, S., Rajic, N., Urosevic, I., Sekulic, B., Kvrgic, V. & Popovic, S., Jul 1 2012, In : Pathology and Oncology Research. 18, 3, p. 681-690 10 p.

Research output: Contribution to journal › Article

Myelodysplastic Syndromes
Microvessels
Vascular Endothelial Growth Factor A
Survival
Acute Myeloid Leukemia

An identical, complex TP53 mutation arising independently in two unrelated families with diverse cancer profiles: The complexity of interpreting cancer risk in carriers

Pinto, E. M., Ribeiro, R. C., Li, J., Taja-Chayeb, L., Carrasco, L. F., De Lourdes Peña-Torres, M., Vidal-Millán, S., Maldonado-Mtz, H., Dueñas-González, A., McGregor, L. & Zambetti, G. P., Nov 13 2012, In : Oncogenesis. 1, 2, e1.

Research output: Contribution to journal › Article

Mutation
Germ-Line Mutation
Neoplasms
Exons
Choroid Plexus Neoplasms
21 Citations (Scopus)

An implantable Fabry-Pérot pressure sensor fabricated on left ventricular assist device for heart failure

Zhou, M. D., Yang, C., Liu, Z., Cysyk, J. & Zheng, S., Feb 1 2012, In : Biomedical Microdevices. 14, 1, p. 235-245 11 p.

Research output: Contribution to journal › Article

Left ventricular assist devices
Equipment Failure
Heart-Assist Devices
Pressure sensors
Heart Failure
10 Citations (Scopus)

An inhibitor of nuclear scaffold protease blocks chemical transformation of fibroblasts.

Clawson, G., Norbeck, L. L., Wise, J. P. & Patierno, S. R., Jan 1 1993, In : Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research. 4, 7, p. 589-594 6 p.

Research output: Contribution to journal › Article

Nuclear Matrix
Peptide Hydrolases
Fibroblasts
Growth
Endoplasmic Reticulum
52 Citations (Scopus)

An integrative approach to the assessment of narcissism

Roche, M. J., Pincus, A. L., Lukowitsky, M. R., Menard, K. S. & Conroy, D. E., May 1 2013, In : Journal of Personality Assessment. 95, 3, p. 237-248 12 p.

Research output: Contribution to journal › Article

Narcissism
Research
1124 Citations (Scopus)

An intergroup phase III comparison of standard radiation therapy and two schedules of concurrent chemoradiotherapy in patients with unresectable squamous cell head and neck cancer

Adelstein, D. J., Li, Y., Adams, G. L., Wagner Jr., H., Kish, J. A., Ensley, J. F., Schuller, D. E. & Forastiere, A. A., Jan 1 2003, In : Journal of Clinical Oncology. 21, 1, p. 92-98 7 p.

Research output: Contribution to journal › Article

Squamous Cell Neoplasms
Chemoradiotherapy
Head and Neck Neoplasms
Appointments and Schedules
Arm
5 Citations (Scopus)

An interstitial deletion within 9p21.3 and extending beyond CDKN2A predisposes to melanoma, neural system tumours and possible haematological malignancies

Baker, M. J., Goldstein, A. M., Gordon, P. L., Harbaugh, K. S., Mackley, H. B., Glantz, M. J. & Drabick, J. J., Nov 1 2016, In : Journal of medical genetics. 53, 11, p. 721-727 7 p.

Research output: Contribution to journal › Article

Cyclin-Dependent Kinase Inhibitor p16
Hematologic Neoplasms
Melanoma
Dysplastic Nevus Syndrome
Neoplasms

An intestinal occlusion device for prevention of small bowel distention during transgastric natural orifice transluminal endoscopic surgery

Tomasko, J. M., Mathew, A., Moyer, M., Haluck, R. & Pauli, E., Jan 1 2013, In : Journal of the Society of Laparoendoscopic Surgeons. 17, 2, p. 306-311 6 p.

Research output: Contribution to journal › Article

Natural Orifice Endoscopic Surgery
Balloon Occlusion
Equipment and Supplies
Catheters
Insufflation
53 Citations (Scopus)

An in vitro model for analysis of oxidative death in primary mouse astrocytes

Robb, S. J. & Connor, J., Mar 30 1998, In : Brain research. 788, 1-2, p. 125-132 8 p.

Research output: Contribution to journal › Article

Astrocytes
L-Lactate Dehydrogenase
Oxidative Stress
Iron
Iron Compounds
10 Citations (Scopus)

An irradiation-free nonmyeloablative bone marrow transplantation model: Importance of the balance between donor T-cell number and the intensity of conditioning

Kuwatani, M., Ikarashi, Y., Mineishi, S., Asaka, M. & Wakasugi, H., Nov 1 2005, In : Transplantation. 80, 9, p. 1145-1152 8 p.

Research output: Contribution to journal › Article

Bone Marrow Transplantation
Bone Marrow Cells
Cell Count
T-Lymphocytes
Immunosuppressive Agents
7 Citations (Scopus)

An observational study of the temporal and spatial patterns of Marek's-disease-associated leukosis condemnation of young chickens in the United States of America

Kennedy, D. A., Dunn, J. R., Dunn, P. & Read, A. F., Jul 1 2015, In : Preventive Veterinary Medicine. 120, 3-4, p. 328-335 8 p.

Research output: Contribution to journal › Article

Marek Disease
Marek disease
observational studies
Observational Studies
Chickens
79 Citations (Scopus)

Anoikis, initiated by MCL-1 degradation and Bim induction, is deregulated during oncogenesis

Woods, N. T., Yamaguchi, H., Lee, F. Y., Bhalla, K. N. & Wang, H. G., Nov 15 2007, In : Cancer Research. 67, 22, p. 10744-10752 9 p.

Research output: Contribution to journal › Article

Anoikis
Carcinogenesis
Glycogen Synthase Kinase 3
1-Phosphatidylinositol 4-Kinase
Mitogen-Activated Protein Kinases
7 Citations (Scopus)

A non-cleavable hexahistidine affinity tag at the carboxyl-terminus of the HIV-1 Pr55Gag polyprotein alters nucleic acid binding properties

Bewley, M. C., Reinhart, L., Stake, M. S., Nadaraia-Hoke, S., Parent, L. J. & Flanagan, J. M., Feb 1 2017, In : Protein Expression and Purification. 130, p. 137-145 9 p.

Research output: Contribution to journal › Article

His-His-His-His-His-His
Polyproteins
Nucleic Acids
HIV-1
HIV
2 Citations (Scopus)

A non-coding cationic lipid DNA complex produces lasting anti-leukemic effects

Keasey, N., Herse, Z., Chang, S., Liggitt, D. H., Lay, M., Fairman, J. & Claxton, D. F., Sep 15 2010, In : Cancer Biology and Therapy. 10, 6, p. 625-631 7 p.

Research output: Contribution to journal › Article

Lipids
DNA
Tachyphylaxis
Leukemia
Interferon-gamma
11 Citations (Scopus)

A non-cytotoxic N-dehydroabietylamine derivative with potent antimalarial activity

Sadashiva, M. P., Gowda, R., Wu, X., Inamdar, G. S., Kuzu, O. F., Rangappa, K. S., Robertson, G. P. & Gowda, D. C., Aug 1 2015, In : Experimental Parasitology. 155, p. 68-73 6 p.

Research output: Contribution to journal › Article

Antimalarials
Inhibitory Concentration 50
Parasites
Diterpenes
Malaria
9 Citations (Scopus)

A noninvasive approach to determine viscoelastic properties of an individual adherent cell under fluid flow

Qiu, J., Baik, A. D., Lu, X. L., Hillman, E. M. C., Zhuang, Z., Dong, C. & Guo, X. E., Apr 11 2014, In : Journal of Biomechanics. 47, 6, p. 1537-1541 5 p.

Research output: Contribution to journal › Article

Flow of fluids
Mechanical properties
Fluid structure interaction
Microscopic examination
Viscosity
3 Citations (Scopus)

A nonradioactive plate-based assay for stimulators of nonspecific DNA nicking by HIV-1 integrase and other nucleases

Sudol, M., Tran, M., Nowak, M. G., Flanagan, J., Robertson, G. & Katzman, M., Jan 15 2010, In : Analytical Biochemistry. 396, 2, p. 223-230 8 p.

Research output: Contribution to journal › Article

Integrases
Assays
DNA
Antiviral Agents
Small Molecule Libraries

A nonsense mutation in COL4A4 gene causing isolated hematuria in either heterozygous or homozygous state

Yang, C., Song, Y., Chen, Z., Yuan, X., Chen, X., Ding, G., Guan, Y., McGrath, M., Song, C., Tong, Y. & Wang, H., Jan 1 2019, In : Frontiers in Genetics. 10, JUL, 628.

Research output: Contribution to journal › Article

Open Access
Hereditary Nephritis
Nonsense Codon
Hematuria
Genes
Glomerular Basement Membrane
14 Citations (Scopus)

An open-label study to describe pharmacokinetic parameters of erlotinib in patients with advanced solid tumors with adequate and moderately impaired hepatic function

O'Bryant, C. L., Haluska, P., Rosen, L., Ramanathan, R. K., Venugopal, B., Leong, S., Boinpally, R., Franke, A., Witt, K., Evans, J., Belani, C., Gail Eckhardt, S. & Ramalingam, S., Mar 1 2012, In : Cancer Chemotherapy and Pharmacology. 69, 3, p. 605-612 8 p.

Research output: Contribution to journal › Article

Pharmacokinetics
Labels
Tumors
Liver
Neoplasms
30 Citations (Scopus)

An opioid growth factor regulates the replication of microorganisms

Zagon, I. & McLaughlin, P., Jan 1 1992, In : Life Sciences. 50, 16, p. 1179-1187 9 p.

Research output: Contribution to journal › Article

Microorganisms
Opioid Analgesics
Intercellular Signaling Peptides and Proteins
Opioid Receptors
Enkephalins
63 Citations (Scopus)

An oriental herbal cocktail, ka-mi-kae-kyuk-tang, exerts anti-cancer activities by targeting angiogenesis, apoptosis and metastasis

Lee, H. J., Lee, E. O., Rhee, Y. H., Ahn, K. S., Li, G. X., Jiang, C., Lü, J. & Kim, S. H., Dec 1 2006, In : Carcinogenesis. 27, 12, p. 2455-2463 9 p.

Research output: Contribution to journal › Article

Apoptosis
Neoplasm Metastasis
Lewis Lung Carcinoma
Blood Vessels
Neoplasms

A novel approach to radiographic image resolution gauge fabrication

Trivelpiece, C. L., Babcox, B. L., Brenizer, J. S., Wolfe, D. E. & Adair, J. H., Aug 1 2011, In : Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment. 646, 1, p. 135-141 7 p.

Research output: Contribution to journal › Article

image resolution
Image resolution
Gages
Fabrication
fabrication
7 Citations (Scopus)

A novel biologically active acid stable liposomal formulation of docosahexaenoic acid in human breast cancer cell lines

Skibinski, C. G., Das, A., Chen, K-M., Liao, J. J., Manni, A., Kester, M. & El-Bayoumy, K., May 25 2016, In : Chemico-Biological Interactions. 252, p. 1-8 8 p.

Research output: Contribution to journal › Article

Docosahexaenoic Acids
Cells
Breast Neoplasms
Cell Line
Acids
9 Citations (Scopus)

A novel bisphosphonate inhibitor of squalene synthase combined with a statin or a nitrogenous bisphosphonate in vitro

Wasko, B. M., Smits, J. P., Shull, L. W., Wiemer, D. F. & Hohl, R. J., Nov 1 2011, In : Journal of Lipid Research. 52, 11, p. 1957-1964 8 p.

Research output: Contribution to journal › Article

zoledronic acid
Farnesyl-Diphosphate Farnesyltransferase
Protein Prenylation
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Lovastatin
45 Citations (Scopus)

A novel class of pyranocoumarin anti-androgen receptor signaling compounds

Guo, J., Jiang, C., Wang, Z., Lee, H. J., Hu, H., Malewicz, B., Lee, H. J., Lee, J. H., Baek, N. I., Jeong, J. H., Kim, D. K., Kang, K. S., Kim, S. H. & Lu, J., Mar 1 2007, In : Molecular cancer therapeutics. 6, 3, p. 907-917 11 p.

Research output: Contribution to journal › Article

Pyranocoumarins
Androgen Receptors
Androgens
Ligands
Prostatic Neoplasms