Research Output 1965 2019


Extending AIC to best subset regression

Liao, J. J., Cavanaugh, J. E. & McMurry, T. L., Jun 1 2018, In : Computational Statistics. 33, 2, p. 787-806 20 p.

Research output: Contribution to journalArticle

Akaike Information Criterion
Model Selection
Multistage Model
1 Citation (Scopus)
Autoimmune Experimental Encephalomyelitis
Opioid Analgesics
Multiple Sclerosis
Intercellular Signaling Peptides and Proteins
1 Citation (Scopus)
Patient Care
Genetic Testing
1 Citation (Scopus)

G4941K substitution in the pore-lining S6 helix of the skeletal muscle ryanodine receptor increases RyR1 sensitivity to ytosolic and luminal Ca2+

Xu, L., Mowrey, D. D., Chirasani, V. R., Wang, Y., Pasek, D. A., Dokholyan, N. V. & Meissner, G., Jan 1 2018, In : Journal of Biological Chemistry. 293, 6, p. 2015-2028 14 p.

Research output: Contribution to journalArticle

S 6
Ryanodine Receptor Calcium Release Channel
Skeletal Muscle
1 Citation (Scopus)

Game theory of tumor–stroma interactions in multiple myeloma: Effect of nonlinear benefits

Sartakhti, J. S., Manshaei, M. H. & Archetti, M., Jun 1 2018, In : Games. 9, 2, 32.

Research output: Contribution to journalArticle

Open Access
Game theory
Game Theory
Growth Factors
1 Citation (Scopus)

Gamma Knife radiosurgery of saccular aneurysms in a rabbit model

Meadowcroft, M., Cooper, T. K., Rupprecht, S., Wright, T. C., Neely, E. E., Ferenci, M., Kang, W., Yang, Q., Harbaugh, R., Connor, J. & McInerney, J., Jan 1 2018, In : Journal of neurosurgery. 129, 6, p. 1530-1540 11 p.

Research output: Contribution to journalArticle

Arteriovenous Malformations
4 Citations (Scopus)

General method to find the attractors of discrete dynamic models of biological systems

Gan, X. & Albert, R. Z., Apr 17 2018, In : Physical Review E. 97, 4, 042308.

Research output: Contribution to journalArticle

Discrete Dynamics
Discrete Model
Biological Systems
dynamic models
62 Citations (Scopus)

Genome-wide Analyses Identify KIF5A as a Novel ALS Gene

ITALSGEN Consortium, Genomic Translation for ALS Care (GTAC) Consortium, ALS Sequencing Consortium, NYGC ALS Consortium, Answer ALS Foundation, Clinical Research in ALS and Related Disorders for Therapeutic Development (CReATe) Consortium, SLAGEN Consortium, French ALS Consortium & Project MinE ALS Sequencing Consortium, Mar 21 2018, In : Neuron. 97, 6, p. 1268-1283.e6

Research output: Contribution to journalArticle

Genome-Wide Association Study
18 Citations (Scopus)

Glioblastoma stem cell-derived exosomes induce M2 macrophages and PD-L1 expression on human monocytes

Gabrusiewicz, K., Li, X., Wei, J., Hashimoto, Y., Marisetty, A. L., Ott, M., Wang, F., Hawke, D., Yu, J., Healy, L. M., Hossain, A., Akers, J. C., Maiti, S. N., Yamashita, S., Shimizu, Y., Dunner, K., Zal, M. A., Burks, J. K., Gumin, J., Nwajei, F. & 15 others, Rezavanian, A., Zhou, S., Rao, G., Sawaya, R., Fuller, G. N., Huse, J. T., Antel, J. P., Li, S., Cooper, L., Sulman, E. P., Chen, C., Geula, C., Kalluri, R., Zal, T. & Heimberger, A. B., Apr 3 2018, In : OncoImmunology. 7, 4, e1412909.

Research output: Contribution to journalArticle

Open Access
Stem Cells

GPx3 supports ovarian cancer progression by manipulating the extracellular redox environment

Worley, B. L., Kim, Y. S., Mardini, J., Zaman, R., Leon, K. E., Vallur, P. G., Nduwumwami, A., Warrick, J., Timmins, P. F., Kesterson, J., Phaeton, R., Lee, N. Y., Walter, V., Endres, L., Mythreye, K., Aird, K. & Hempel, N., Jan 1 2018, (Accepted/In press) In : Redox Biology.

Research output: Contribution to journalArticle

Glutathione Peroxidase
Ovarian Neoplasms
Hepatitis C Antibodies
Tissue Donors
1 Citation (Scopus)

HFE Genotype Restricts the Response to Paraquat in a Mouse Model of Neurotoxicity

Nixon, A. M., Meadowcroft, M. D., Neely, E. B., Snyder, A. M., Purnell, C. J., Wright, J., Lamendella, R., Nandar, W., Huang, X. & Connor, J. R., May 2018, In : Journal of neurochemistry. 145, 4, p. 299-311 13 p.

Research output: Contribution to journalArticle

Substantia Nigra
Tyrosine 3-Monooxygenase
7 Citations (Scopus)

Highly photostable nanogels for fluorescence-based theranostics

Gyawali, D., Kim, J. P. & Yang, J., Mar 1 2018, In : Bioactive Materials. 3, 1, p. 39-47 9 p.

Research output: Contribution to journalArticle

Biodegradable polymers
Citric acid
Cell death
11 Citations (Scopus)

High-speed atomic force microscopy reveals structural dynamics of α -synuclein monomers and dimers

Zhang, Y., Hashemi, M., Lv, Z., Williams, B., Popov, K. I., Dokholyan, N. & Lyubchenko, Y. L., Mar 28 2018, In : Journal of Chemical Physics. 148, 12, 123322.

Research output: Contribution to journalArticle

dynamic structural analysis
Structural dynamics
Atomic force microscopy

Hospitalizations for fracture in patients with metastatic disease: Primary source lesions in the United States

Nikkel, L., Mahmood, B., Lander, S., Maceroli, M., Fox, E., Tyler, W., Karbach, L. & Elfar, J., Feb 1 2018, In : Journal of Community and Supportive Oncology. 16, 1, p. e14-e20

Research output: Contribution to journalArticle

Spontaneous Fractures
Organized Financing
Kidney Neoplasms
Costs and Cost Analysis
1 Citation (Scopus)

Hybrid Synthetic-Biological Hydrogel System for Adipose Tissue Regeneration

Li, S., Poche, J. N., Liu, Y., Scherr, T., McCann, J., Forghani, A., Smoak, M., Muir, M., Berntsen, L., Chen, C., Ravnic, D., Gimble, J. & Hayes, D. J., Nov 1 2018, In : Macromolecular Bioscience. 18, 11, 1800122.

Research output: Contribution to journalArticle

Tissue regeneration
Extracellular Matrix
Adipose Tissue

Identification and quantification of novel major metabolites of the steroidal aromatase inhibitor, exemestane

Luo, S., Chen, G., Truica, C., Baird, C. C., Xia, Z. & Lazarus, P., Dec 1 2018, In : Drug Metabolism and Disposition. 46, 12, p. 1867-1878 12 p.

Research output: Contribution to journalArticle

Aromatase Inhibitors
5 Citations (Scopus)

Identification of WEE1 as a target to make AKT inhibition more effective in melanoma

Kuzu, O. F., Gowda, R., Sharma, A., Noory, M. A., Kardos, G., Madhunapantula, S. R. V., Drabick, J. & Robertson, G., Jan 2 2018, In : Cancer Biology and Therapy. 19, 1, p. 53-62 10 p.

Research output: Contribution to journalArticle

RNA Interference
Cell Cycle Checkpoints
DNA Repair
DNA Damage
2 Citations (Scopus)

Identifying (un)controllable dynamical behavior in complex networks

Rozum, J. C. & Albert, R. Z., Dec 1 2018, In : PLoS computational biology. 14, 12, e1006630.

Research output: Contribution to journalArticle

Cell signaling
Complex networks
Robust control
6 Citations (Scopus)

Impact of macromolecular crowding on RNA/spermine complex coacervation and oligonucleotide compartmentalization

Marianelli, A. M., Miller, B. M. & Keating, C. D., Jan 1 2018, In : Soft Matter. 14, 3, p. 368-378 11 p.

Research output: Contribution to journalArticle

Polyethylene glycols
13 Citations (Scopus)

Impact of Surgical Resection of the Primary Tumor on Overall Survival in Patients with Metastatic Pheochromocytoma or Sympathetic Paraganglioma

Roman-Gonzalez, A., Zhou, S., Ayala-Ramirez, M., Shen, C., Waguespack, S. G., Habra, M. A., Karam, J. A., Perrier, N., Wood, C. G. & Jimenez, C., Jul 1 2018, In : Annals of surgery. 268, 1, p. 172-178 7 p.

Research output: Contribution to journalArticle

Confidence Intervals
23 Citations (Scopus)

Inactivated varicella zoster vaccine in autologous haemopoietic stem-cell transplant recipients: an international, multicentre, randomised, double-blind, placebo-controlled trial

V212 Protocol 001 Trial Team, May 26 2018, In : The Lancet. 391, 10135, p. 2116-2127 12 p.

Research output: Contribution to journalArticle

Herpes Zoster Vaccine
Chickenpox Vaccine
Inactivated Vaccines
Stem Cells
6 Citations (Scopus)

Increased Cardiac Arrhythmogenesis Associated with Gap Junction Remodeling with Upregulation of RNA-Binding Protein FXR1

Chu, M., Novak, S. M., Cover, C., Wang, A. A., Chinyere, I. R., Juneman, E. B., Zarnescu, D. C., Wong, P. K. & Gregorio, C. C., Feb 6 2018, In : Circulation. 137, 6, p. 605-618 14 p.

Research output: Contribution to journalArticle

RNA-Binding Proteins
Gap Junctions
Dilated Cardiomyopathy
Heart Diseases
2 Citations (Scopus)

Increased O-GlcNAcylation of SNAP29 drives arsenicinduced autophagic dysfunction

Dodson, M., Liu, P., Jiang, T., Ambrose, A. J., Luo, G., de la Vega, M. R., Cholanians, A. B., Wong, P. K., Chapman, E. & Zhang, D. D., Jun 1 2018, In : Molecular and cellular biology. 38, 11, e00595-17.

Research output: Contribution to journalArticle

SNARE Proteins
Clustered Regularly Interspaced Short Palindromic Repeats
3 Citations (Scopus)
Indocyanine Green
Methylene Blue

Infant brachial neuritis following a viral prodrome: a case in a 6-month old child and review of the literature

Mrowczynski, O. D., Langan, S. T. & Rizk, E., Jan 1 2018, In : Child's Nervous System. 34, 1, p. 173-176 4 p.

Research output: Contribution to journalArticle

Brachial Plexus Neuritis
Upper Extremity
3 Citations (Scopus)

Inhibin is a novel paracrine factor for tumor angiogenesis and metastasis

Singh, P., Jenkins, L. M., Horst, B., Alers, V., Pradhan, S., Kaur, P., Srivastava, T., Hempel, N., Gyorffy, B., Broude, E. V., Lee, N. Y. & Mythreye, K., Jun 1 2018, In : Cancer Research. 78, 11, p. 2978-2989 12 p.

Research output: Contribution to journalArticle

Angiogenesis Inducing Agents
Neoplasm Metastasis

Inhibition of migration and invasion in melanoma cells by β-escin via the ERK/NF-κB signaling pathway

Kwak, H. S., An, H., Alam, M. B., Choi, W. S., Lee, S. & Lee, S. H., Jan 1 2018, In : Biological and Pharmaceutical Bulletin. 41, 10, p. 1606-1610 5 p.

Research output: Contribution to journalArticle

NF-kappa B
Cell Movement
6 Citations (Scopus)

Insights into Roseburia intestinalis which alleviates experimental colitis pathology by inducing anti-inflammatory responses

Shen, Z., Zhu, C., Quan, Y., Yang, J-M., Yuan, W., Yang, Z., Wu, S., Luo, W., Tan, B. & Wang, X., Oct 1 2018, In : Journal of Gastroenterology and Hepatology (Australia). 33, 10, p. 1751-1760 10 p.

Research output: Contribution to journalArticle

Crohn Disease
Anti-Inflammatory Agents
Regulatory T-Lymphocytes
2 Citations (Scopus)

In Situ Caging of Biomolecules in Graphene Hybrids for Light Modulated Bioactivity

Cheng, G., Han, X. H., Hao, S. J., Nisic, M. & Zheng, S., Jan 31 2018, In : ACS Applied Materials and Interfaces. 10, 4, p. 3361-3371 11 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Institution-wide and Within-Patient Evolution of Daptomycin Susceptibility in Vancomycin-Resistant Enterococcus faecium Bloodstream Infections

Woods, R. J., Patel, T. S., Nagel, J. L., Newton, D. W. & Read, A. F., Feb 1 2018, In : Infection Control and Hospital Epidemiology. 39, 2, p. 226-228 3 p.

Research output: Contribution to journalArticle

Enterococcus faecium
Microbial Sensitivity Tests
Vancomycin-Resistant Enterococci
2 Citations (Scopus)

Integration of biochemical and biomechanical signals regulating endothelial barrier function

Sanabria, V. A. & Dong, C., Jan 1 2018, In : MCB Molecular and Cellular Biomechanics. 15, 1, p. 1-19 19 p.

Research output: Contribution to journalArticle

Endothelial Cells
Vascular Diseases
Vascular Endothelial Growth Factor A
21 Citations (Scopus)

Integrative detection and analysis of structural variation in cancer genomes

Dixon, J. R., Xu, J., Dileep, V., Zhan, Y., Song, F., Le, V. T., Yardımcı, G. G., Chakraborty, A., Bann, D. V., Wang, Y., Clark, R., Zhang, L., Yang, H., Liu, T., Iyyanki, S., An, L., Pool, C., Sasaki, T., Rivera-Mulia, J. C., Ozadam, H. & 17 others, Lajoie, B. R., Kaul, R., Buckley, M., Lee, K., Diegel, M., Pezic, D., Ernst, C., Hadjur, S., Odom, D. T., Stamatoyannopoulos, J. A., Broach, J. R., Hardison, R. C., Ay, F., Noble, W. S., Dekker, J., Gilbert, D. M. & Yue, F., Oct 1 2018, In : Nature Genetics. 50, 10, p. 1388-1398 11 p.

Research output: Contribution to journalArticle

Genomic Structural Variation
DNA Replication Timing
Sequence Deletion
Primary Health Care
Mental Health
Cross-Sectional Studies
1 Citation (Scopus)
Petrous Bone
Peripheral Nerves
Cranial Nerves
20 Citations (Scopus)

Intraoperative Pancreatic Cancer Detection using Tumor-Specific Multimodality Molecular Imaging

Tummers, W. S., Miller, S. E., Teraphongphom, N. T., Gomez, A., Steinberg, I., Huland, D. M., Hong, S., Kothapalli, S-R., Hasan, A., Ertsey, R., Bonsing, B. A., Vahrmeijer, A. L., Swijnenburg, R. J., Longacre, T. A., Fisher, G. A., Gambhir, S. S., Poultsides, G. A. & Rosenthal, E. L., Jul 1 2018, In : Annals of Surgical Oncology. 25, 7, p. 1880-1888 9 p.

Research output: Contribution to journalArticle

Molecular Imaging
Pancreatic Neoplasms
Optical Imaging
1 Citation (Scopus)

Introduction to the Special Issue on Approaches to Control Biological and Biologically Inspired Networks

Albert, R. Z., Baillieul, J. & Motter, A. E., Jun 1 2018, In : IEEE Transactions on Control of Network Systems. 5, 2, p. 690-693 4 p.

Research output: Contribution to journalArticle

Biological Control
Biological systems
Control theory
Network Modeling
Control Theory
1 Citation (Scopus)

In vitro and in vivo antitumor and anti-inflammatory capabilities of the novel GSK3 and CDK9 inhibitor ABC1183s

Schrecengost, R. S., Green, C. L., Zhuang, Y., Keller, S. N., Smith, R. A., Maines, L. W. & Smith, C., Apr 1 2018, In : Journal of Pharmacology and Experimental Therapeutics. 365, 1, p. 107-116 10 p.

Research output: Contribution to journalArticle

Cyclin-Dependent Kinase 9
Anti-Inflammatory Agents
Peptide Elongation Factors
Glycogen Synthase Kinases
5 Citations (Scopus)

In vitro cytocompatibility evaluation of poly(octamethylene citrate) monomers toward their use in orthopedic regenerative engineering

Ma, C., Gerhard, E., Lin, Q., Xia, S., Armstrong, A. & Yang, J., Mar 1 2018, In : Bioactive Materials. 3, 1, p. 19-27 9 p.

Research output: Contribution to journalArticle

Citric Acid
7 Citations (Scopus)

Involvement of the central somatosensory system in restless legs syndrome: A neuroimaging study

Lee, B. Y., Kim, J., Connor, J., Podskalny, G. D., Ryu, Y. & Yang, Q., May 22 2018, In : Neurology. 90, 21, p. e1834-e1841

Research output: Contribution to journalArticle

Restless Legs Syndrome
Somatosensory Cortex
Corpus Callosum

Isolated limb infusion as a treatment option for malignant granular cell tumour

Tian, Y., Fox, E., Drabick, J. & Pameijer, C. R., Jan 1 2018, In : BMJ case reports. 2018, 224618.

Research output: Contribution to journalArticle

Granular Cell Tumor
9 Citations (Scopus)

Large SOD1 aggregates, unlike trimeric SOD1, do not impact cell viability in a model of amyotrophic lateral sclerosis

Zhu, C., Beck, M. V., Griffith, J. D., Deshmukh, M. & Dokholyan, N., May 1 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 18, p. 4661-4665 5 p.

Research output: Contribution to journalArticle

Amyotrophic Lateral Sclerosis
Cell Survival
Motor Neurons
Neurodegenerative Diseases
1 Citation (Scopus)

Ligand binding to a remote site thermodynamically corrects the F508del mutation in the human cystic fibrosis transmembrane conductance regulator

Wang, C., Aleksandrov, A. A., Yang, Z., Forouhar, F., Proctor, E. A., Kota, P., An, J., Kaplan, A., Khazanov, N., Boël, G., Stockwell, B. R., Senderowitz, H., Dokholyan, N., Riordan, J. R., Brouillette, C. G. & Hunt, J. F., Jan 1 2018, In : Journal of Biological Chemistry. 293, 46, p. 17685-17704 20 p.

Research output: Contribution to journalArticle

Cystic Fibrosis Transmembrane Conductance Regulator
5 Citations (Scopus)

Light-Emitting Transition Metal Dichalcogenide Monolayers under Cellular Digestion

Yeh, Y-T., Tang, Y., Lin, Z., Fujisawa, K., Lei, Y., Zhou, Y., Rotella, C., Elias Arriaga, A. L., Zheng, S., Mao, Y., Liu, Z., Lu, H. & Terrones Maldonado, M., Feb 22 2018, In : Advanced Materials. 30, 8, 1703321.

Research output: Contribution to journalArticle

Transition metals
7 Citations (Scopus)

Loss of E2F7 confers resistance to poly-ADP-ribose polymerase (PARP) inhibitors in BRCA2-deficient cells

Clements, K. E., Thakar, T., Nicolae, C., Liang, X., Wang, H-G. & Moldovan, G-L., Jan 1 2018, In : Nucleic acids research. 46, 17, p. 8898-8907 10 p.

Research output: Contribution to journalArticle

Recombinational DNA Repair
Tumor Biomarkers
DNA Replication
6 Citations (Scopus)

Low-level arsenic causes proteotoxic stress and not oxidative stress

Dodson, M., de la Vega, M. R., Harder, B., Castro-Portuguez, R., Rodrigues, S. D., Wong, P. K., Chapman, E. & Zhang, D. D., Feb 15 2018, In : Toxicology and Applied Pharmacology. 341, p. 106-113 8 p.

Research output: Contribution to journalArticle

Oxidative stress
Oxidative Stress
4 Citations (Scopus)

Maintenance DFMO Increases Survival in High Risk Neuroblastoma

Sholler, G. L. S., Ferguson, W., Bergendahl, G., Bond, J. P., Neville, K., Eslin, D., Brown, V., Roberts, W., Wada, R. K., Oesterheld, J., Mitchell, D., Foley, J., Parikh, N. S., Eshun, F., Zage, P., Rawwas, J., Sencer, S., Pankiewicz, D., Quinn, M., Rich, M. & 2 others, Junewick, J. & Kraveka, J. M., Dec 1 2018, In : Scientific reports. 8, 1, 14445.

Research output: Contribution to journalArticle

Open Access
Disease-Free Survival

Management of Large Cecal Polyps: When Can the Ileocecal Valve Be Spared?

Kulaylat, A. S., Boltz, M., Moyer, M., Mathew, A., McKenna, K. & Messaris, E., Sep 1 2018, In : Diseases of the Colon and Rectum. 61, 9, p. 1089-1095 7 p.

Research output: Contribution to journalArticle

Ileocecal Valve
Length of Stay
Colonic Polyps

Mapping allosteric linkage to channel gating by extracellular domains in the human epithelial sodium channel

Shobair, M., Popov, K. I., Dang, Y. L., He, H., Jackson Stutts, M. & Dokholyan, N., Jan 1 2018, In : Journal of Biological Chemistry. 293, 10, p. 3675-3684 10 p.

Research output: Contribution to journalArticle

Epithelial Sodium Channels
Chromosome Mapping
Degenerin Sodium Channels
Chemical activation
6 Citations (Scopus)

Mechanisms of MAFG Dysregulation in Cholestatic Liver Injury and Development of Liver Cancer

Liu, T., Yang, H., Fan, W., Tu, J., Li, T. W. H., Wang, J., Shen, H., Yang, J. W., Xiong, T., Steggerda, J., Liu, Z., Noureddin, M., Maldonado, S. S., Annamalai, A., Seki, E., Mato, J. M. & Lu, S. C., Aug 2018, In : Gastroenterology. 155, 2, p. 557-571.e14

Research output: Contribution to journalArticle

Basic-Leucine Zipper Transcription Factors
Liver Neoplasms
Wounds and Injuries