Cancer Institute, Mechanisms of Carcinogenesis

  • United States

Organization profile

Organization profile

Research Interests

Fingerprint The fingerprint is based on mining the text of the scientific documents related to the associated persons. Based on that an index of weighted terms is created, which defines the key subjects of research unit

DNA Medicine & Life Sciences
Proteins Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
T-Lymphocytes Medicine & Life Sciences
Enzymes Medicine & Life Sciences
Genes Medicine & Life Sciences
Carcinogenesis Medicine & Life Sciences
Liver Medicine & Life Sciences

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Profiles

No photo of Stephen Benkovic
1963 …2021

Research Output 1963 2019

Aldehyde dehydrogenase in regulatory T-cell development, immunity and cancer

Bazewicz, C. G., Dinavahi, S. S., Schell, T. & Robertson, G., Jan 1 2019, In : Immunology. 156, 1, p. 47-55 9 p.

Research output: Contribution to journalReview article

Aldehyde Dehydrogenase
Regulatory T-Lymphocytes
Immunity
Neoplasms
Immune Tolerance

ASR352, A potent anticancer agent: Synthesis, preliminary SAR, and biological activities against colorectal cancer bulk, 5-fluorouracil/oxaliplatin resistant and stem cells

Narayan, S., Ramisetti, S., Jaiswal, A. S., Law, B. K., Singh-Pillay, A., Singh, P., Amin, S. & Sharma, A., Jan 1 2019, In : European Journal of Medicinal Chemistry. 161, p. 456-467 12 p.

Research output: Contribution to journalArticle

oxaliplatin
Bioactivity
Stem cells
Fluorouracil
Antineoplastic Agents

Berberine directly affects the gut microbiota to promote intestinal farnesoid X receptor activation

Tian, Y., Cai, J., Gui, W., Nichols, R. G., Koo, I., Zhang, J., Anitha, M. & Patterson, A. D., Feb 1 2019, In : Drug Metabolism and Disposition. 47, 2, p. 86-93 8 p.

Research output: Contribution to journalArticle

Berberine
Bacteria
choloylglycine hydrolase
Metabolomics
Bile Acids and Salts

Calcium signalling in T cells

Trebak, M. & Kinet, J. P., Jan 1 2019, (Accepted/In press) In : Nature Reviews Immunology.

Research output: Contribution to journalArticle

Calcium Signaling
T-Lymphocytes
Immunity
Cell Membrane
Lymphocytes

Cell and Animal Models for Studying Hepatitis B Virus Infection and Drug Development

Hu, J., Lin, Y. Y., Chen, P. J., Watashi, K. & Wakita, T., Jan 1 2019, In : Gastroenterology. 156, 2, p. 338-354 17 p.

Research output: Contribution to journalArticle

Virus Diseases
Hepatitis B virus
Animal Models
Pharmaceutical Preparations
Cell Culture Techniques

Development of Isoselenocyanate Compounds' Syntheses and Biological Applications

Frieben, E. E., Amin, S. & Sharma, A., Jan 1 2019, (Accepted/In press) In : Journal of Medicinal Chemistry.

Research output: Contribution to journalArticle

Sulfur
Isothiocyanates
Neoplasms
Organoselenium Compounds
Glucosinolates

DNA polymerases as chemotherapy targets: Promise and challenges

Eckert, K. & Barnes, R. P., Jan 1 2019, In : Oncotarget. 10, 6, p. 620-621 2 p.

Research output: Contribution to journalEditorial

DNA-Directed DNA Polymerase
Drug Therapy

Dual role of a C-terminally truncated isoform of large tumor suppressor kinase 1 in the regulation of hippo signaling and tissue growth

Matsui, Y., Zhang, Y., Paulson, R. & Lai, Z., Jan 1 2019, In : DNA and Cell Biology. 38, 1, p. 91-106 16 p.

Research output: Contribution to journalArticle

Protein Isoforms
Phosphotransferases
Growth
Neoplasms
Drosophila

Emissions of Free Radicals, Carbonyls, and Nicotine from the NIDA Standardized Research Electronic Cigarette and Comparison to Similar Commercial Devices

Bitzer, Z. T., Goel, R., Reilly, S. M., Bhangu, G., Trushin, N., Foulds, J., Muscat, J. & Richie, J., Jan 22 2019, In : Chemical Research in Toxicology. 32, 1, p. 130-138 9 p.

Research output: Contribution to journalReview article

National Institute on Drug Abuse (U.S.)
Aerosols
Nicotine
Tobacco Products
Free Radicals

HIV–HBV and HIV–HCV coinfection and liver cancer development

Hu, J., Liu, K. & Luo, J., Jan 1 2019, Cancer Treatment and Research. Springer International Publishing, p. 231-250 20 p. (Cancer Treatment and Research; vol. 177).

Research output: Chapter in Book/Report/Conference proceedingChapter

Liver Neoplasms
Coinfection
Hepatitis B virus
Hepacivirus
HIV

Projects 2012 2023

THE ROLE OF NONO IN TAZ-DRIVEN GLIOMA MALIGNANT TRANSFORMATION

Li, W.

9/1/187/31/23

Project: Research projectIndividual grant

Polymerase Switching During Translesion DNA Synthesis within the Human System

Hedglin, M.

National Institutes of Health

9/1/128/31/15

Project: Research projectPostdoctoral Individual National Research Service Award

DNA-Directed DNA Polymerase
DNA
DNA Replication
Mutation
Neoplasms