Cancer Institute, Mechanisms of Carcinogenesis

  • United States

Organization profile

Organization profile

Research Interests

Fingerprint The fingerprint is based on mining the text of the scientific documents related to the associated persons. Based on that an index of weighted terms is created, which defines the key subjects of research unit

DNA Medicine & Life Sciences
Proteins Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Peroxisome Proliferator-Activated Receptors Medicine & Life Sciences
T-Lymphocytes Medicine & Life Sciences
Genes Medicine & Life Sciences
Enzymes Medicine & Life Sciences
Carcinogenesis Medicine & Life Sciences

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Profiles

Research Output 1963 2019

A calcium/cAMP signaling loop at the ORAI1 mouth drives channel inactivation to shape NFAT induction

Zhang, X., Pathak, T., Yoast, R., Emrich, S., Xin, P., Nwokonko, R. M., Johnson, M., Wu, S., Delierneux, C., Gueguinou, M., Hempel, N., Putney, J. W., Gill, D. & Trebak, M., Dec 1 2019, In : Nature communications. 10, 1, 1971.

Research output: Contribution to journalArticle

Open Access
Calcium Signaling
mouth
deactivation
Mouth
calcium

Advanced NSCLC patients with high IL-6 levels have altered peripheral T cell population and signaling

Rice, S. J., Liu, X., Zhang, J., Jia, B., Zheng, H. & Belani, C., May 1 2019, In : Lung Cancer. 131, p. 58-61 4 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Interleukin-6
T-Lymphocytes
Population
STAT1 Transcription Factor
1 Citation (Scopus)

Aldehyde dehydrogenase in regulatory T-cell development, immunity and cancer

Bazewicz, C. G., Dinavahi, S. S., Schell, T. & Robertson, G., Jan 1 2019, In : Immunology. 156, 1, p. 47-55 9 p.

Research output: Contribution to journalReview article

Aldehyde Dehydrogenase
Regulatory T-Lymphocytes
Immunity
Neoplasms
Immune Tolerance

Aluminum oxide free-standing thin films to enable nitrogen edge soft X-ray scattering

Ye, D., Rongpipi, S., Litofsky, J. H., Lee, Y., Culp, T. E., Yoo, S. H., Jackson, T. N., Wang, C., Gomez, E. W. & Gomez, E. D., Mar 1 2019, In : MRS Communications. 9, 1, p. 224-228 5 p.

Research output: Contribution to journalArticle

Aluminum Oxide
X ray scattering
Nitrogen
Aluminum
X rays

ASR352, A potent anticancer agent: Synthesis, preliminary SAR, and biological activities against colorectal cancer bulk, 5-fluorouracil/oxaliplatin resistant and stem cells

Narayan, S., Ramisetti, S., Jaiswal, A. S., Law, B. K., Singh-Pillay, A., Singh, P., Amin, S. & Sharma, A., Jan 1 2019, In : European Journal of Medicinal Chemistry. 161, p. 456-467 12 p.

Research output: Contribution to journalArticle

oxaliplatin
Bioactivity
Stem cells
Fluorouracil
Antineoplastic Agents

Berberine directly affects the gut microbiota to promote intestinal farnesoid X receptor activation

Tian, Y., Cai, J., Gui, W., Nichols, R. G., Koo, I., Zhang, J., Anitha, M. & Patterson, A. D., Feb 1 2019, In : Drug Metabolism and Disposition. 47, 2, p. 86-93 8 p.

Research output: Contribution to journalArticle

Berberine
Bacteria
choloylglycine hydrolase
Metabolomics
Bile Acids and Salts

Brain cholesterol metabolism and Parkinson's disease

Huang, X., Sterling, N. W., Du, G., Sun, D., Stetter, C., Kong, L., Zhu, Y., Neighbors, J., Lewis, M., Chen, H., Hohl, R. & Mailman, R., Mar 1 2019, In : Movement Disorders. 34, 3, p. 386-395 10 p.

Research output: Contribution to journalArticle

Parkinson Disease
Cholesterol
Brain
Odds Ratio
Logistic Models
2 Citations (Scopus)

Calcium signalling in T cells

Trebak, M. & Kinet, J. P., Mar 1 2019, In : Nature Reviews Immunology. 19, 3, p. 154-169 16 p.

Research output: Contribution to journalReview article

Calcium Signaling
T-Lymphocytes
Immunity
Cell Membrane
Lymphocytes
2 Citations (Scopus)

Cell and Animal Models for Studying Hepatitis B Virus Infection and Drug Development

Hu, J., Lin, Y. Y., Chen, P. J., Watashi, K. & Wakita, T., Jan 1 2019, In : Gastroenterology. 156, 2, p. 338-354 17 p.

Research output: Contribution to journalArticle

Virus Diseases
Hepatitis B virus
Animal Models
Pharmaceutical Preparations
Cell Culture Techniques

Characterizing protein-DNA binding event subtypes in ChIP-exo data

Yamada, N., Lai, W., Farrell, N., Pugh, B. F. & Mahony, S. A., Mar 15 2019, In : Bioinformatics. 35, 6, p. 903-913 11 p.

Research output: Contribution to journalArticle

DNA-binding Protein
Chromatin Immunoprecipitation
Chromatin
DNA-Binding Proteins
DNA

Projects 2012 2023

DNA-Directed DNA Polymerase
DNA
DNA Replication
Mutation
Neoplasms

Activities 2005 2016

  • 3 Oral presentation