Research Output

2020

Alteration of CTCF-associated chromatin neighborhood inhibits TAL1-driven oncogenic transcription program and leukemogenesis

Li, Y., Liao, Z., Luo, H., Benyoucef, A., Kang, Y., Lai, Q., Dovat, S., Miller, B., Chepelev, I., Li, Y., Zhao, K., Brand, M. & Huang, S., Apr 6 2020, In : Nucleic acids research. 48, 6, p. 3119-3133 15 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

An Efficient Synthesis of Dibenzo[a,l]tetracene and Dibenzo[a,j]tetracene and Their Identification in a Coal Tar Extract

Ramisetti, S. R., Oña-Ruales, J. O., Wise, S. A., Amin, S. & Sharma, A. K., Jan 1 2020, In : Polycyclic Aromatic Compounds. 40, 1, p. 88-98 11 p.

Research output: Contribution to journalArticle

An integrative view of the regulatory and transcriptional landscapes in mouse hematopoiesis

Xiang, G., Keller, C. A., Heuston, E., Giardine, B. M., An, L., Wixom, A. Q., Miller, A., Cockburn, A., Sauria, M. E. G., Weaver, K., Lichtenberg, J., Göttgens, B., Li, Q., Bodine, D., Mahony, S., Taylor, J., Blobel, G. A., Weiss, M. J., Cheng, Y., Yue, F. & 4 others, Hughes, J., Higgs, D. R., Zhang, Y. & Hardison, R. C., Jan 1 2020, In : Genome research. 30, 3, p. 472-484 13 p.

Research output: Contribution to journalArticle

Open Access

Antibacterial effects of low-temperature plasma generated by atmospheric-pressure plasma jet are mediated by reactive oxygen species

Nicol, M. K. J., Brubaker, T. R., Honish, B. J., Simmons, A. N., Kazemi, A., Geissel, M. A., Whalen, C. T., Siedlecki, C. A., Bilén, S. G., Knecht, S. D. & Kirimanjeswara, G. S., Dec 1 2020, In : Scientific reports. 10, 1, 3066.

Research output: Contribution to journalArticle

Open Access

Ceramide analogue SACLAC modulates sphingolipid levels and MCL-1 splicing to induce apoptosis in acute myeloid leukemia

Pearson, J. M., Tan, S. F., Sharma, A., Annageldiyev, C., Fox, T. E., Abad, J. L., Fabrias, G., Desai, D., Amin, S., Wang, H. G., Cabot, M. C., Claxton, D. F., Kester, M., Feith, D. J. & Loughran, T. P., Jan 1 2020, In : Molecular Cancer Research. 18, 3, p. 352-363 12 p.

Research output: Contribution to journalArticle

Change is Good: What is New for ToxSci?

Peters, J. M., Jan 1 2020, In : Toxicological Sciences. 173, 1, p. 1-2 2 p.

Research output: Contribution to journalEditorial

1 Scopus citations

ChExMix: A Method for Identifying and Classifying Protein-DNA Interaction Subtypes

Yamada, N., Kuntala, P. K., Pugh, B. F. & Mahony, S., Mar 2020, In : Journal of Computational Biology. 27, 3, p. 429-435 7 p.

Research output: Contribution to journalArticle

Open Access

Clinical and Genetic Factors Associated With Complications After Crohn's Ileocolectomy

Kline, B. P., Weaver, T., Brinton, D. L., Deiling, S., Yochum, G. S., Berg, A. S. & Koltun, W. A., Mar 1 2020, In : Diseases of the colon and rectum. 63, 3, p. 357-364 8 p.

Research output: Contribution to journalArticle

Composite score analysis for unsupervised comparison and network visualization of metabolomics data

Kellogg, J. J., Kvalheim, O. M. & Cech, N. B., Jan 25 2020, In : Analytica Chimica Acta. 1095, p. 38-47 10 p.

Research output: Contribution to journalArticle

1 Scopus citations

Context-dependent activation of SIRT3 is necessary for anchorage-independent survival and metastasis of ovarian cancer cells

Kim, Y. S., Gupta Vallur, P., Jones, V. M., Worley, B. L., Shimko, S., Shin, D. H., Crawford, L. T. C., Chen, C. W., Aird, K. M., Abraham, T., Shepherd, T. G., Warrick, J. I., Lee, N. Y., Phaeton, R., Mythreye, K. & Hempel, N., Feb 20 2020, In : Oncogene. 39, 8, p. 1619-1633 15 p.

Research output: Contribution to journalArticle

Customized Prevention Trials Could Resolve the Controversy of the Effects of Omega-3 Fatty Acids on Cancer

El-Bayoumy, K. & Manni, A., Feb 17 2020, In : Nutrition and cancer. 72, 2, p. 183-186 4 p.

Research output: Contribution to journalComment/debate

1 Scopus citations

Design, synthesis characterization and biological evaluation of novel multi-isoform ALDH inhibitors as potential anticancer agents

Dinavahi, S. S., Gowda, R., Bazewicz, C. G., Battu, M. B., Lin, J. M., Chitren, R. J., Pandey, M. K., Amin, S., Robertson, G. P. & Gowda, K., Feb 1 2020, In : European Journal of Medicinal Chemistry. 187, 111962.

Research output: Contribution to journalArticle

Development of a Novel Multi-Isoform ALDH Inhibitor Effective as an Antimelanoma Agent

Dinavahi, S. S., Gowda, R., Gowda, K., Bazewicz, C. G., Chirasani, V. R., Battu, M. B., Berg, A., Dokholyan, N. V., Amin, S. & Robertson, G. P., Feb 1 2020, In : Molecular cancer therapeutics. 19, 2, p. 447-459 13 p.

Research output: Contribution to journalArticle

Electrostatic Interactions Govern Extreme Nascent Protein Ejection Times from Ribosomes and Can Delay Ribosome Recycling

Nissley, D. A., Vu, Q. V., Trovato, F., Ahmed, N., Jiang, Y., Li, M. S. & O'Brien, E. P., Apr 1 2020, In : Journal of the American Chemical Society. 142, 13, p. 6103-6110 8 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Exogenous Signaling Molecules Released from Aptamer-Functionalized Hydrogels Promote the Survival of Mesenchymal Stem Cell Spheroids

Zhao, N., Coyne, J., Abune, L., Shi, P., Lian, X. L., Zhang, G. & Wang, Y., Jan 1 2020, (Accepted/In press) In : ACS Applied Materials and Interfaces.

Research output: Contribution to journalArticle

Fluorescent indicators for continuous and lineage-specific reporting of cell-cycle phases in human pluripotent stem cells

Chang, Y., Hellwarth, P. B., Randolph, L. N., Sun, Y., Xing, Y., Zhu, W., Lian, X. L. & Bao, X., Jul 1 2020, In : Biotechnology and bioengineering. 117, 7, p. 2177-2186 10 p.

Research output: Contribution to journalArticle

Forcing the ribosome to change its message

Leininger, S. E., Deutsch, C. & O’Brien, E. P., May 15 2020, In : Journal of Biological Chemistry. 295, 20, p. 6809-6810 2 p.

Research output: Contribution to journalReview article

Open Access

Gastrointestinal hypoalgesia in inflammatory bowel disease

Coates, M. D., Soriano, C., Dalessio, S., Stuart, A., Walter, V., Koltun, W., Bernasko, N., Tinsley, A., Clarke, K. & Williams, E. D., Jan 1 2020, In : Annals of Gastroenterology. 33, 1, p. 45-52 8 p.

Research output: Contribution to journalArticle

Open Access

Heart regeneration with human pluripotent stem cells: Prospects and challenges

Jiang, Y. & Lian, X. L., Mar 2020, In : Bioactive Materials. 5, 1, p. 74-81 8 p.

Research output: Contribution to journalReview article

Open Access
1 Scopus citations

Hierarchical Markov State Model Building to Describe Molecular Processes

Wolfe, D. K., Persichetti, J. R., Sharma, A. K., Hudson, P. S., Woodcock, H. L. & O'brien, E. P., Mar 10 2020, In : Journal of Chemical Theory and Computation. 16, 3, p. 1816-1826 11 p.

Research output: Contribution to journalArticle

High-affinity mutant Interleukin-13 targeted CAR T cells enhance delivery of clickable biodegradable fluorescent nanoparticles to glioblastoma

Kim, G. B., Aragon-Sanabria, V., Randolph, L., Jiang, H., Reynolds, J. A., Webb, B. S., Madhankumar, A., Lian, X., Connor, J. R., Yang, J. & Dong, C., Sep 2020, In : Bioactive Materials. 5, 3, p. 624-635 12 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Hypermethylation of FOXA1 and allelic loss of PTEN drive squamous differentiation and promote heterogeneity in bladder cancer

Osei-Amponsa, V., Buckwalter, J. M., Shuman, L., Zheng, Z., Yamashita, H., Walter, V., Wildermuth, T., Ellis-Mohl, J., Liu, C., Warrick, J. I., Shantz, L. M., Feehan, R. P., Al-Ahmadie, H., Mendelsohn, C., Raman, J. D., Kaestner, K. H., Wu, X. R. & DeGraff, D. J., Feb 6 2020, In : Oncogene. 39, 6, p. 1302-1317 16 p.

Research output: Contribution to journalArticle

2 Scopus citations

Identification of adulteration in botanical samples with untargeted metabolomics

Wallace, E. D., Todd, D. A., Harnly, J. M., Cech, N. B. & Kellogg, J. J., Jul 1 2020, In : Analytical and Bioanalytical Chemistry. 412, 18, p. 4273-4286 14 p.

Research output: Contribution to journalArticle

IL-37/ STAT3/ HIF-1α negative feedback signaling drives gemcitabine resistance in pancreatic cancer

Zhao, T., Jin, F., Xiao, D., Wang, H., Huang, C., Wang, X., Gao, S., Liu, J., Yang, S. & Hao, J., Jan 1 2020, In : Theranostics. 10, 9, p. 4088-4100 13 p.

Research output: Contribution to journalArticle

Open Access

Involvement of host atr-chk1 pathway in hepatitis b virus covalently closed circular dna formation

Luo, J., Luckenbaugh, L., Hu, H., Yan, Z., Gao, L. & Hu, J., Jan 1 2020, In : mBio. 11, 1, e03423-19.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Knocking down raptor in human keratinocytes affects ornithine decarboxylase in a post-transcriptional Manner following ultraviolet B exposure

Stump, C. L., Feehan, R. P., Jordan, T., Shantz, L. M. & Nowotarski, S. L., Feb 1 2020, In : Amino Acids. 52, 2, p. 141-149 9 p.

Research output: Contribution to journalArticle

1 Scopus citations

Lipid-Functionalized Graphene Loaded with hMnSOD for Selective Inhibition of Cancer Cells

Farell, M., Self, A., Guza, C., Song, H., Apollon, L., Gomez, E. W. & Kumar, M., Mar 18 2020, In : ACS Applied Materials and Interfaces. 12, 11, p. 12407-12416 10 p.

Research output: Contribution to journalArticle

Lipidic synthetic alkaloids as SK3 channel modulators. Synthesis and biological evaluation of 2-substituted tetrahydropyridine derivatives with potential anti-metastatic activity

Kouba, S., Braire, J., Félix, R., Chantôme, A., Jaffrès, P. A., Lebreton, J., Dubreuil, D., Pipelier, M., Zhang, X., Trebak, M., Vandier, C., Mathé-Allainmat, M. & Potier-Cartereau, M., Jan 15 2020, In : European Journal of Medicinal Chemistry. 186, 111854.

Research output: Contribution to journalArticle

Matrix metalloproteinases cleave membrane-bound PD-L1 on CD90+ (myo-)fibroblasts in Crohn’s disease and regulate Th1/Th17 cell responses

Aguirre, J. E., Beswick, E. J., Grim, C., Uribe, G., Tafoya, M., Palma, G. C., Samedi, V., McKee, R., Villeger, R., Fofanov, Y., Cong, Y., Yochum, G., Koltun, W., Powell, D. & Pinchuk, I. V., Jan 1 2020, In : International immunology. 32, 1, p. 57-68 12 p.

Research output: Contribution to journalArticle

Metabolomics and mass spectrometry imaging reveal channeled de novo purine synthesis in cells

Pareek, V., Tian, H., Winograd, N. & Benkovic, S. J., Apr 17 2020, In : Science. 368, 6488, p. 283-290 8 p.

Research output: Contribution to journalArticle

4 Scopus citations
Open Access

Microbial Metabolite Signaling Is Required for Systemic Iron Homeostasis

Das, N. K., Schwartz, A. J., Barthel, G., Inohara, N., Liu, Q., Sankar, A., Hill, D. R., Ma, X., Lamberg, O., Schnizlein, M. K., Arqués, J. L., Spence, J. R., Nunez, G., Patterson, A. D., Sun, D., Young, V. B. & Shah, Y. M., Jan 7 2020, In : Cell Metabolism. 31, 1, p. 115-130.e6

Research output: Contribution to journalArticle

5 Scopus citations

MicroRNA profile in stage I clear cell renal cell carcinoma predicts progression to metastatic disease

Moynihan, M. J., Sullivan, T. B., Burks, E., Schober, J., Calabrese, M., Fredrick, A., Kalantzakos, T., Warrick, J., Canes, D., Raman, J. D. & Rieger-Christ, K., Jan 1 2020, (Accepted/In press) In : Urologic Oncology: Seminars and Original Investigations.

Research output: Contribution to journalArticle

Moving forward with ToxSci

Peters, J. M., Feb 1 2020, In : Toxicological Sciences. 173, 2, p. 227-228 2 p.

Research output: Contribution to journalEditorial

Open Access
Open Access

Multi-scale Predictions of Drug Resistance Epidemiology Identify Design Principles for Rational Drug Design

Leighow, S. M., Liu, C., Inam, H., Zhao, B. & Pritchard, J. R., Mar 24 2020, In : Cell Reports. 30, 12, p. 3951-3963.e4

Research output: Contribution to journalArticle

Open Access

Mutational profile of endometrial hyperplasia and risk of progression to endometrioid adenocarcinoma

Russo, M., Newell, J. M., Budurlean, L., Houser, K. R., Sheldon, K., Kesterson, J., Phaeton, R., Hossler, C., Rosenberg, J., DeGraff, D., Shuman, L., Broach, J. R. & Warrick, J. I., Jun 15 2020, In : Cancer. 126, 12, p. 2775-2783 9 p.

Research output: Contribution to journalArticle

Open Access

PCB126 blocks the thermogenic beiging response of adipocytes

Gourronc, F. A., Perdew, G. H., Robertson, L. W. & Klingelhutz, A. J., Mar 1 2020, In : Environmental Science and Pollution Research. 27, 9, p. 8897-8904 8 p.

Research output: Contribution to journalArticle

PD-L1 is a direct target of cancer-FOXP3 in pancreatic ductal adenocarcinoma (PDAC), and combined immunotherapy with antibodies against PD-L1 and CCL5 is effective in the treatment of PDAC

Wang, X., Li, X., Wei, X., Jiang, H., Lan, C., Yang, S., Wang, H., Yang, Y., Tian, C., Xu, Z., Zhang, J., Hao, J. & Ren, H., Dec 1 2020, In : Signal Transduction and Targeted Therapy. 5, 1, 38.

Research output: Contribution to journalArticle

Open Access

Perfluorooctane sulfonate alters gut microbiota-host metabolic homeostasis in mice

Zhang, L., Rimal, B., Nichols, R. G., Tian, Y., Smith, P. B., Hatzakis, E., Chang, S. C., Butenhoff, J. L., Peters, J. M. & Patterson, A. D., Feb 15 2020, In : Toxicology. 431, 152365.

Research output: Contribution to journalArticle

Phase separation directs ubiquitination of gene-body nucleosomes

Gallego, L. D., Schneider, M., Mittal, C., Romanauska, A., Gudino Carrillo, R. M., Schubert, T., Pugh, B. F. & Köhler, A., Mar 26 2020, In : Nature. 579, 7800, p. 592-597 6 p.

Research output: Contribution to journalArticle

3 Scopus citations

Publisher Correction: Molecular basis of microhomology-mediated end-joining by purified full-length Polθ (Nature Communications, (2019), 10, 1, (4423), 10.1038/s41467-019-12272-9)

Black, S. J., Ozdemir, A. Y., Kashkina, E., Kent, T., Rusanov, T., Ristic, D., Shin, Y., Suma, A., Hoang, T., Chandramouly, G., Siddique, L. A., Borisonnik, N., Sullivan-Reed, K., Mallon, J. S., Skorski, T., Carnevale, V., Murakami, K. S., Wyman, C. & Pomerantz, R. T., Dec 1 2020, In : Nature communications. 11, 1, 1831.

Research output: Contribution to journalComment/debate

Open Access

Quantification for non-targeted LC/MS screening without standard substances

Liigand, J., Wang, T., Kellogg, J., Smedsgaard, J., Cech, N. & Kruve, A., Dec 1 2020, In : Scientific reports. 10, 1, 5808.

Research output: Contribution to journalArticle

Open Access

Rad6/Rad18 Competes with DNA Polymerases ν and δfor PCNA Encircling DNA

Li, M., Larsen, L. & Hedglin, M., Feb 4 2020, In : Biochemistry. 59, 4, p. 407-416 10 p.

Research output: Contribution to journalArticle

1 Scopus citations

Report from the International Society of Urological Pathology (ISUP) Consultation Conference on Molecular Pathology of Urogenital Cancers. II. Molecular Pathology of Bladder Cancer: Progress and Challenges

Warrick, J. I., Knowles, M. A., Yves, A., Van Der Kwast, T., Grignon, D. J., Kristiansen, G., Egevad, L., Hartmann, A. & Cheng, L., Jan 1 2020, (Accepted/In press) In : American Journal of Surgical Pathology.

Research output: Contribution to journalArticle

1 Scopus citations

RNA-binding domains of heterologous viral proteins substituted for basic residues in the RSV gag NC domain restore specific packaging of genomic RNA

Rice, B. L., Lochmann, T. L. & Parent, L. J., Jan 1 2020, In : Viruses. 12, 4, 370.

Research output: Contribution to journalArticle

Open Access