Research Output per year
Research Output
2020
An Efficient Synthesis of Dibenzo[a,l]tetracene and Dibenzo[a,j]tetracene and Their Identification in a Coal Tar Extract
Ramisetti, S. R., Oña-Ruales, J. O., Wise, S. A., Amin, S. & Sharma, A. K., Jan 1 2020, In : Polycyclic Aromatic Compounds. 40, 1, p. 88-98 11 p.Research output: Contribution to journal › Article
Ceramide analogue SACLAC modulates sphingolipid levels and MCL-1 splicing to induce apoptosis in acute myeloid leukemia
Pearson, J. M., Tan, S. F., Sharma, A., Annageldiyev, C., Fox, T. E., Abad, J. L., Fabrias, G., Desai, D., Amin, S., Wang, H. G., Cabot, M. C., Claxton, D. F., Kester, M., Feith, D. J. & Loughran, T. P., Jan 1 2020, In : Molecular Cancer Research. 18, 3, p. 352-363 12 p.Research output: Contribution to journal › Article
Composite score analysis for unsupervised comparison and network visualization of metabolomics data
Kellogg, J. J., Kvalheim, O. M. & Cech, N. B., Jan 25 2020, In : Analytica Chimica Acta. 1095, p. 38-47 10 p.Research output: Contribution to journal › Article
Context-dependent activation of SIRT3 is necessary for anchorage-independent survival and metastasis of ovarian cancer cells
Kim, Y. S., Gupta Vallur, P., Jones, V. M., Worley, B. L., Shimko, S., Shin, D. H., Crawford, L. T. C., Chen, C. W., Aird, K. M., Abraham, T., Shepherd, T. G., Warrick, J. I., Lee, N. Y., Phaeton, R., Mythreye, K. & Hempel, N., Feb 20 2020, In : Oncogene. 39, 8, p. 1619-1633 15 p.Research output: Contribution to journal › Article
Design, synthesis characterization and biological evaluation of novel multi-isoform ALDH inhibitors as potential anticancer agents
Dinavahi, S. S., Gowda, R., Bazewicz, C. G., Battu, M. B., Lin, J. M., Chitren, R. J., Pandey, M. K., Amin, S., Robertson, G. P. & Gowda, K., Feb 1 2020, In : European Journal of Medicinal Chemistry. 187, 111962.Research output: Contribution to journal › Article
Development of a Novel Multi-Isoform ALDH Inhibitor Effective as an Antimelanoma Agent
Dinavahi, S. S., Gowda, R., Gowda, K., Bazewicz, C. G., Chirasani, V. R., Battu, M. B., Berg, A., Dokholyan, N. V., Amin, S. & Robertson, G. P., Feb 1 2020, In : Molecular cancer therapeutics. 19, 2, p. 447-459 13 p.Research output: Contribution to journal › Article
Evaluation of PD-L1 and other immune markers in bladder urothelial carcinoma stratified by histologic variants and molecular subtypes
Li, H., Zhang, Q., Shuman, L., Kaag, M., Raman, J. D., Merrill, S., DeGraff, D. J., Warrick, J. I. & Chen, G., Dec 1 2020, In : Scientific reports. 10, 1, 1439.Research output: Contribution to journal › Article
Open Access
Gastrointestinal hypoalgesia in inflammatory bowel disease
Coates, M. D., Soriano, C., Dalessio, S., Stuart, A., Walter, V., Koltun, W., Bernasko, N., Tinsley, A., Clarke, K. & Williams, E. D., Jan 1 2020, In : Annals of Gastroenterology. 33, 1, p. 45-52 8 p.Research output: Contribution to journal › Article
Open Access
Hypermethylation of FOXA1 and allelic loss of PTEN drive squamous differentiation and promote heterogeneity in bladder cancer
Osei-Amponsa, V., Buckwalter, J. M., Shuman, L., Zheng, Z., Yamashita, H., Walter, V., Wildermuth, T., Ellis-Mohl, J., Liu, C., Warrick, J. I., Shantz, L. M., Feehan, R. P., Al-Ahmadie, H., Mendelsohn, C., Raman, J. D., Kaestner, K. H., Wu, X. R. & DeGraff, D. J., Feb 6 2020, In : Oncogene. 39, 6, p. 1302-1317 16 p.Research output: Contribution to journal › Article
IL-37/ STAT3/ HIF-1α negative feedback signaling drives gemcitabine resistance in pancreatic cancer
Zhao, T., Jin, F., Xiao, D., Wang, H., Huang, C., Wang, X., Gao, S., Liu, J., Yang, S. & Hao, J., Jan 1 2020, In : Theranostics. 10, 9, p. 4088-4100 13 p.Research output: Contribution to journal › Article
Open Access
Knocking down raptor in human keratinocytes affects ornithine decarboxylase in a post-transcriptional Manner following ultraviolet B exposure
Stump, C. L., Feehan, R. P., Jordan, T., Shantz, L. M. & Nowotarski, S. L., Feb 1 2020, In : Amino Acids. 52, 2, p. 141-149 9 p.Research output: Contribution to journal › Article
1
Scopus
citations
Lipidic synthetic alkaloids as SK3 channel modulators. Synthesis and biological evaluation of 2-substituted tetrahydropyridine derivatives with potential anti-metastatic activity
Kouba, S., Braire, J., Félix, R., Chantôme, A., Jaffrès, P. A., Lebreton, J., Dubreuil, D., Pipelier, M., Zhang, X., Trebak, M., Vandier, C., Mathé-Allainmat, M. & Potier-Cartereau, M., Jan 15 2020, In : European Journal of Medicinal Chemistry. 186, 111854.Research output: Contribution to journal › Article
Metatranscriptomic analysis of the mouse gut microbiome response to the persistent organic pollutant 2,3,7,8-tetrachlorodibenzofuran
Nichols, R. G., Zhang, J., Cai, J., Murray, I. A., Koo, I., Smith, P. B., Perdew, G. H. & Patterson, A. D., Jan 2020, In : Metabolites. 10, 1, 1.Research output: Contribution to journal › Article
Open Access
Microbial Metabolite Signaling Is Required for Systemic Iron Homeostasis
Das, N. K., Schwartz, A. J., Barthel, G., Inohara, N., Liu, Q., Sankar, A., Hill, D. R., Ma, X., Lamberg, O., Schnizlein, M. K., Arqués, J. L., Spence, J. R., Nunez, G., Patterson, A. D., Sun, D., Young, V. B. & Shah, Y. M., Jan 7 2020, In : Cell Metabolism. 31, 1, p. 115-130.e6Research output: Contribution to journal › Article
2
Scopus
citations
Multi-dimensional analysis identifies an immune signature predicting response to decitabine treatment in elderly patients with AML
Zhao, C., Jia, B., Wang, M., Schell, T. D., Claxton, D. F., Ehmann, W. C., Rybka, W. B., Mineishi, S., Naik, S., Songdej, N., Sivik, J. M., Hohl, R. J., Zeng, H. & Zheng, H., Mar 1 2020, In : British Journal of Haematology. 188, 5, p. 674-684 11 p.Research output: Contribution to journal › Article
Open Access
PCB126 blocks the thermogenic beiging response of adipocytes
Gourronc, F. A., Perdew, G. H., Robertson, L. W. & Klingelhutz, A. J., Mar 1 2020, In : Environmental Science and Pollution Research. 27, 9, p. 8897-8904 8 p.Research output: Contribution to journal › Article
Perfluorooctane sulfonate alters gut microbiota-host metabolic homeostasis in mice
Zhang, L., Rimal, B., Nichols, R. G., Tian, Y., Smith, P. B., Hatzakis, E., Chang, S. C., Butenhoff, J. L., Peters, J. M. & Patterson, A. D., Feb 15 2020, In : Toxicology. 431, 152365.Research output: Contribution to journal › Article
Report from the International Society of Urological Pathology (ISUP) Consultation Conference on Molecular Pathology of Urogenital Cancers. II. Molecular Pathology of Bladder Cancer: Progress and Challenges
Warrick, J. I., Knowles, M. A., Yves, A., Van Der Kwast, T., Grignon, D. J., Kristiansen, G., Egevad, L., Hartmann, A. & Cheng, L., Jan 1 2020, (Accepted/In press) In : American Journal of Surgical Pathology.Research output: Contribution to journal › Article
Selective Ah receptor modulators attenuate NPC1L1-mediated cholesterol uptake through repression of SREBP-2 transcriptional activity
Muku, G. E., Kusnadi, A., Kuzu, G., Tanos, R., Murray, I. A., Gowda, K., Amin, S. & Perdew, G. H., Feb 1 2020, In : Laboratory Investigation. 100, 2, p. 250-264 15 p.Research output: Contribution to journal › Article
Structural basis of reiterative transcription from the pyrG and pyrBI promoters by bacterial RNA polymerase
Shin, Y., Hedglin, M. & Murakami, K. S., Feb 28 2020, In : Nucleic acids research. 48, 4, p. 2144-2155 12 p.Research output: Contribution to journal › Article
Open Access
The ability of two chlorine dioxide chemistries to inactivate human papillomavirus-contaminated endocavitary ultrasound probes and nasendoscopes
Meyers, C., Milici, J. & Robison, R., Jan 1 2020, (Accepted/In press) In : Journal of Medical Virology.Research output: Contribution to journal › Article
Open Access
The Dopamine D2 Receptor Contributes to the Spheroid Formation Behavior of U87 Glioblastoma Cells
Weissenrieder, J. S., Reed, J. L., Green, M. V., Moldovan, G. L., Koubek, E. J., Neighbors, J. D. & Hohl, R. J., Jan 1 2020, In : Pharmacology. 105, 1-2, p. 19-27 9 p.Research output: Contribution to journal › Article
Open Access
The microbiome modulating activity of bile acids
Tian, Y., Gui, W., Koo, I., Smith, P. B., Allman, E. L., Nichols, R. G., Rimal, B., Cai, J., Liu, Q. & Patterson, A. D., Jan 1 2020, (Accepted/In press) In : Gut microbes.Research output: Contribution to journal › Article
The novel Isatin analog KS99 targets stemness markers in acute myeloid leukemia
Annageldiyev, C., Gowda, K., Patel, T., Bhattacharya, P., Tan, S. F., Iyer, S., Desai, D., Dovat, S., Feith, D. J., Loughran, T. P., Amin, S., Claxton, D. & Sharma, A., Mar 1 2020, In : Haematologica. 105, 3, p. 687-696 10 p.Research output: Contribution to journal › Article
Open Access
The primary mechanism of cytotoxicity of the chemotherapeutic agent CX-5461 is topoisomerase II poisoning
Bruno, P. M., Lu, M., Dennis, K. A., Inam, H., Moore, C. J., Sheehe, J., Elledge, S. J., Hemann, M. T. & Pritchard, J. R., Feb 25 2020, In : Proceedings of the National Academy of Sciences of the United States of America. 117, 8, p. 4053-4060 8 p.Research output: Contribution to journal › Article
2019
2-C-methylated nucleotides terminate virus RNA synthesis by preventing active site closure of the viral RNA-dependent RNA polymerase
Boehr, A. K., Arnold, J. J., Oh, H. S., Cameron, C. E. & Boehr, D. D., Jan 1 2019, In : Journal of Biological Chemistry. 294, 45, p. 16897-16907 11 p.Research output: Contribution to journal › Article
Abstracts of Presentations at the Association of Clinical Scientists 139th Meeting Hershey, PA, May 15-18, 2019
Donaldson, K., Buchanich, J. M., Grigson, P. S., Deneke, E., Vrana, K. E., Sacks, D. B., Kuehn, G. J., Cardamone, D., Pesce, A., Smiley, S., Nickley, J., Krock, K., Thomas, R., Wilkerson, M. L., Farag, H. A., Challa, S. R., Tice, A. M., Wolk, D. M., Prichard, J., Grant, M. L. & 102 others, , May 1 2019, In : Annals of clinical and laboratory science. 49, 3, p. 403-416 14 p.Research output: Contribution to journal › Article
A calcium/cAMP signaling loop at the ORAI1 mouth drives channel inactivation to shape NFAT induction
Zhang, X., Pathak, T., Yoast, R., Emrich, S., Xin, P., Nwokonko, R. M., Johnson, M., Wu, S., Delierneux, C., Gueguinou, M., Hempel, N., Putney, J. W., Gill, D. L. & Trebak, M., Dec 1 2019, In : Nature communications. 10, 1, 1971.Research output: Contribution to journal › Article
Open Access
5
Scopus
citations
Acceptability of electronic nicotine delivery systems (ENDS) among HIV positive smokers
Yingst, J., Foulds, J., Zurlo, J., Steinberg, M. B., Eissenberg, T. & Du, P., Jan 1 2019, (Accepted/In press) In : AIDS Care - Psychological and Socio-Medical Aspects of AIDS/HIV.Research output: Contribution to journal › Article
A chemical kinetic basis for measuring translation initiation and elongation rates from ribosome profiling data
Sharma, A. K., Sormanni, P., Ahmed, N., Ciryam, P., Friedrich, U. A., Kramer, G. & O'Brien, E. P., Jan 1 2019, In : PLoS computational biology. 15, 5, e1007070.Research output: Contribution to journal › Article
Open Access
3
Scopus
citations
Acid ceramidase promotes drug resistance in acute myeloid leukemia through NF-κB-dependent P-glycoprotein upregulation
Tan, S. F., Dunton, W., Liu, X., Fox, T. E., Morad, S. A. F., Desai, D., Doi, K., Conaway, M. R., Amin, S., Claxton, D. F., Wang, H. G., Kester, M., Cabot, M. C., Feith, D. J. & Loughran, T. P., Jan 1 2019, In : Journal of Lipid Research. 60, 6, p. 1078-1086 9 p.Research output: Contribution to journal › Article
1
Scopus
citations
Acute Invasive Fungal Rhinosinusitis: Frozen Section Histomorphology and Diagnosis with PAS Stain
Crist, H., Hennessy, M., Hodos, J., McGinn, J., White, B., Payne, S. & Warrick, J. I., Sep 1 2019, In : Head and Neck Pathology. 13, 3, p. 318-326 9 p.Research output: Contribution to journal › Article
Acute phase protein, α – 1- acid glycoprotein (AGP-1), has differential effects on TLR-2 and TLR-4 mediated responses
Sumanth, M. S., Abhilasha, K. V., Jacob, S. P., Chaithra, V. H., Basrur, V., Willard, B., McIntyre, T. M., Prabhu, K. S. & Marathe, G. K., Sep 2019, In : Immunobiology. 224, 5, p. 672-680 9 p.Research output: Contribution to journal › Article
Advanced NSCLC patients with high IL-6 levels have altered peripheral T cell population and signaling
Rice, S. J., Liu, X., Zhang, J., Jia, B., Zheng, H. & Belani, C. P., May 2019, In : Lung Cancer. 131, p. 58-61 4 p.Research output: Contribution to journal › Article
Aluminum oxide free-standing thin films to enable nitrogen edge soft X-ray scattering
Ye, D., Rongpipi, S., Litofsky, J. H., Lee, Y., Culp, T. E., Yoo, S. H., Jackson, T. N., Wang, C., Gomez, E. W. & Gomez, E. D., Mar 1 2019, In : MRS Communications. 9, 1, p. 224-228 5 p.Research output: Contribution to journal › Article
1
Scopus
citations
A novel hiPSC-derived system for hematoendothelial and myeloid blood toxicity screens identifies compounds promoting and inhibiting endothelial-to-hematopoietic transition
Elcheva, I., Sneed, M., Frazee, S., Liu, Z., Zhu, J., Wood, T., Hendrickson, S., Oehler, C., Garcia, B. & Spiegelman, V. S., Dec 2019, In : Toxicology in Vitro. 61, 104622.Research output: Contribution to journal › Article
A random subset implementation of weighted quantile sum (WQSRS) regression for analysis of high-dimensional mixtures
Curtin, P., Kellogg, J., Cech, N. & Gennings, C., Jan 1 2019, (Accepted/In press) In : Communications in Statistics: Simulation and Computation.Research output: Contribution to journal › Article
2
Scopus
citations
A Selective and Cell-Permeable Mitochondrial Calcium Uniporter (MCU) Inhibitor Preserves Mitochondrial Bioenergetics after Hypoxia/Reoxygenation Injury
Woods, J. J., Nemani, N., Shanmughapriya, S., Kumar, A., Zhang, M., Nathan, S. R., Thomas, M., Carvalho, E., Ramachandran, K., Srikantan, S., Stathopulos, P. B., Wilson, J. J. & Madesh, M., Jan 23 2019, In : ACS Central Science. 5, 1, p. 153-166 14 p.Research output: Contribution to journal › Article
Open Access
13
Scopus
citations
ASR352, A potent anticancer agent: Synthesis, preliminary SAR, and biological activities against colorectal cancer bulk, 5-fluorouracil/oxaliplatin resistant and stem cells
Narayan, S., Ramisetti, S., Jaiswal, A. S., Law, B. K., Singh-Pillay, A., Singh, P., Amin, S. & Sharma, A. K., Jan 1 2019, In : European Journal of Medicinal Chemistry. 161, p. 456-467 12 p.Research output: Contribution to journal › Article
1
Scopus
citations
Berberine directly affects the gut microbiota to promote intestinal farnesoid X receptor activation
Tian, Y., Cai, J., Gui, W., Nichols, R. G., Koo, I., Zhang, J., Anitha, M. & Patterson, A. D., Feb 2019, In : Drug Metabolism and Disposition. 47, 2, p. 86-93 8 p.Research output: Contribution to journal › Article
9
Scopus
citations
Biomimetic Separation of Transport and Matrix Functions in Lamellar Block Copolymer Channel-Based Membranes
Lang, C., Ye, D., Song, W., Yao, C., Tu, Y. M., Capparelli, C., Lanasa, J. A., Hickner, M. A., Gomez, E. W., Gomez, E. D., Hickey, R. J. & Kumar, M., Jul 23 2019, In : ACS nano. 13, 7, p. 8292-8302 11 p.Research output: Contribution to journal › Article
5
Scopus
citations
Blockade of MCU-Mediated Ca 2+ Uptake Perturbs Lipid Metabolism via PP4-Dependent AMPK Dephosphorylation
Tomar, D., Jaña, F., Dong, Z., Quinn, W. J., Jadiya, P., Breves, S. L., Daw, C. C., Srikantan, S., Shanmughapriya, S., Nemani, N., Carvalho, E., Tripathi, A., Worth, A. M., Zhang, X., Razmpour, R., Seelam, A., Rhode, S., Mehta, A. V., Murray, M., Slade, D. & 12 others, , Mar 26 2019, In : Cell Reports. 26, 13, p. 3709-3725.e7Research output: Contribution to journal › Article
Open Access
1
Scopus
citations
Brain cholesterol metabolism and Parkinson's disease
Huang, X., Sterling, N. W., Du, G., Sun, D., Stetter, C., Kong, L., Zhu, Y., Neighbors, J., Lewis, M. M., Chen, H., Hohl, R. J. & Mailman, R. B., Mar 2019, In : Movement Disorders. 34, 3, p. 386-395 10 p.Research output: Contribution to journal › Article
5
Scopus
citations
Cell and Animal Models for Studying Hepatitis B Virus Infection and Drug Development
Hu, J., Lin, Y. Y., Chen, P. J., Watashi, K. & Wakita, T., Jan 2019, In : Gastroenterology. 156, 2, p. 338-354 17 p.Research output: Contribution to journal › Article
10
Scopus
citations
Characterization of histone deacetylase expression within in vitro and in vivo bladder cancer model systems
Buckwalter, J. M., Chan, W., Shuman, L., Wildermuth, T., Ellis-Mohl, J., Walter, V., Warrick, J. I., Wu, X. R., Kaag, M., Raman, J. D. & Degraff, D. J., May 2 2019, In : International journal of molecular sciences. 20, 10, 2599.Research output: Contribution to journal › Article
Open Access
2
Scopus
citations
Characterizing protein-DNA binding event subtypes in ChIP-exo data
Yamada, N., Lai, W. K. M., Farrell, N., Pugh, B. F. & Mahony, S., Mar 15 2019, In : Bioinformatics. 35, 6, p. 903-913 11 p.Research output: Contribution to journal › Article
3
Scopus
citations
Chemically synthesized Secoisolariciresinol diglucoside (LGM2605) improves mitochondrial function in cardiac myocytes and alleviates septic cardiomyopathy
Kokkinaki, D., Hoffman, M., Kalliora, C., Kyriazis, I. D., Maning, J., Lucchese, A. M., Shanmughapriya, S., Tomar, D., Park, J. Y., Wang, H., Yang, X. F., Madesh, M., Lymperopoulos, A., Koch, W. J., Christofidou-Solomidou, M. & Drosatos, K., Feb 2019, In : Journal of Molecular and Cellular Cardiology. 127, p. 232-245 14 p.Research output: Contribution to journal › Article
5
Scopus
citations
Chemical pressure effect on the optical conductivity of the nodal-line semimetals ZrSiY (Y= S,Se,Te) and ZrGeY (Y= S,Te)
Ebad-Allah, J., Afonso, J. F., M., K., Hu, J., Zhu, Y. L., Mao, Z. Q., J., K. & Kuntscher, C. A., 2019, In : Physical Review B. 99, 12Research output: Contribution to journal › Article
5
Scopus
citations
Circulating microRNAs in plasma among men with low-grade and high-grade prostate cancer at prostate biopsy
McDonald, A. C., Vira, M., Walter, V., Shen, J., Raman, J. D., Sanda, M. G., Patil, D. & Taioli, E., Jun 15 2019, In : Prostate. 79, 9, p. 961-968 8 p.Research output: Contribution to journal › Article
2
Scopus
citations
CLARITE Facilitates the Quality Control and Analysis Process for EWAS of Metabolic-Related Traits
Lucas, A. M., Palmiero, N. E., McGuigan, J., Passero, K., Zhou, J., Orie, D., Ritchie, M. D. & Hall, M. A., Dec 18 2019, In : Frontiers in Genetics. 10, 1240.Research output: Contribution to journal › Article
Open Access
1
Scopus
citations