Research Output 1963 2019

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2019
2 Citations (Scopus)

A calcium/cAMP signaling loop at the ORAI1 mouth drives channel inactivation to shape NFAT induction

Zhang, X., Pathak, T., Yoast, R., Emrich, S., Xin, P., Nwokonko, R. M., Johnson, M., Wu, S., Delierneux, C., Gueguinou, M., Hempel, N., Putney, J. W., Gill, D. & Trebak, M., Dec 1 2019, In : Nature communications. 10, 1, 1971.

Research output: Contribution to journalArticle

Open Access
Calcium Signaling
mouth
deactivation
Mouth
calcium
1 Citation (Scopus)

A chemical kinetic basis for measuring translation initiation and elongation rates from ribosome profiling data

Sharma, A. K., Sormanni, P., Ahmed, N., Ciryam, P., Friedrich, U. A., Kramer, G. & O'Brien, Jr., E. P., May 1 2019, In : PLoS computational biology. 15, 5, p. e1007070

Research output: Contribution to journalArticle

Open Access
Chemical Kinetics
Elongation
Profiling
ribosomes
Stem cells
1 Citation (Scopus)

Acid ceramidase promotes drug resistance in acute myeloid leukemia through NF-κB-dependent P-glycoprotein upregulation

Tan, S. F., Dunton, W., Liu, X., Fox, T. E., Morad, S. A. F., Desai, D., Doi, K., Conaway, M. R., Amin, S., Claxton, D., Wang, H. G., Kester, M., Cabot, M. C., Feith, D. J. & Loughran, T. P., Jan 1 2019, In : Journal of Lipid Research. 60, 6, p. 1078-1086 9 p.

Research output: Contribution to journalArticle

Acid Ceramidase
P-Glycoprotein
Drug Resistance
Acute Myeloid Leukemia
Up-Regulation

Acute Invasive Fungal Rhinosinusitis: Frozen Section Histomorphology and Diagnosis with PAS Stain

Crist, H., Hennessy, M., Hodos, J., McGinn, J., White, B., Payne, S. & Warrick, J., Sep 1 2019, In : Head and Neck Pathology. 13, 3, p. 318-326 9 p.

Research output: Contribution to journalArticle

Frozen Sections
Fungi
Coloring Agents
Periodic Acid-Schiff Reaction
Biopsy

Acute phase protein, α – 1- acid glycoprotein (AGP-1), has differential effects on TLR-2 and TLR-4 mediated responses

Sumanth, M. S., Abhilasha, K. V., Jacob, S. P., Chaithra, V. H., Basrur, V., Willard, B., McIntyre, T. M., Prabhu, K. S. & Marathe, G. K., Sep 1 2019, In : Immunobiology. 224, 5, p. 672-680 9 p.

Research output: Contribution to journalArticle

Acute-Phase Proteins
Sepsis
Glycoproteins
Ligands
Acids

Advanced NSCLC patients with high IL-6 levels have altered peripheral T cell population and signaling

Rice, S. J., Liu, X., Zhang, J., Jia, B., Zheng, H. & Belani, C., May 1 2019, In : Lung Cancer. 131, p. 58-61 4 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Interleukin-6
T-Lymphocytes
Population
STAT1 Transcription Factor
1 Citation (Scopus)

Aluminum oxide free-standing thin films to enable nitrogen edge soft X-ray scattering

Ye, D., Rongpipi, S., Litofsky, J. H., Lee, Y., Culp, T. E., Yoo, S. H., Jackson, T. N., Wang, C., Gomez, E. W. & Gomez, E. D., Mar 1 2019, In : MRS Communications. 9, 1, p. 224-228 5 p.

Research output: Contribution to journalArticle

Aluminum Oxide
X ray scattering
Nitrogen
Aluminum
X rays

A novel hiPSC-derived system for hematoendothelial and myeloid blood toxicity screens identifies compounds promoting and inhibiting endothelial-to-hematopoietic transition

Elcheva, I., Sneed, M., Frazee, S., Liu, Z., Zhu, J., Wood, T., Hendrickson, S., Oehler, C., Garcia, B. & Spiegelman, V., Dec 1 2019, In : Toxicology in Vitro. 61, 104622.

Research output: Contribution to journalArticle

Induced Pluripotent Stem Cells
Cytotoxicity
Toxicity
GATA2 Transcription Factor
Screening
3 Citations (Scopus)

A Selective and Cell-Permeable Mitochondrial Calcium Uniporter (MCU) Inhibitor Preserves Mitochondrial Bioenergetics after Hypoxia/Reoxygenation Injury

Woods, J. J., Nemani, N., Santhanam, S., Kumar, A., Zhang, M., Nathan, S. R., Thomas, M., Carvalho, E., Ramachandran, K., Srikantan, S., Stathopulos, P. B., Wilson, J. J. & Madesh, M., Jan 23 2019, In : ACS Central Science. 5, 1, p. 153-166 14 p.

Research output: Contribution to journalArticle

Open Access
Calcium
Signal transduction
Mutagenesis
Ruthenium
Poisons

ASR352, A potent anticancer agent: Synthesis, preliminary SAR, and biological activities against colorectal cancer bulk, 5-fluorouracil/oxaliplatin resistant and stem cells

Narayan, S., Ramisetti, S., Jaiswal, A. S., Law, B. K., Singh-Pillay, A., Singh, P., Amin, S. & Sharma, A., Jan 1 2019, In : European Journal of Medicinal Chemistry. 161, p. 456-467 12 p.

Research output: Contribution to journalArticle

oxaliplatin
Bioactivity
Stem cells
Fluorouracil
Antineoplastic Agents
4 Citations (Scopus)

Berberine directly affects the gut microbiota to promote intestinal farnesoid X receptor activation

Tian, Y., Cai, J., Gui, W., Nichols, R. G., Koo, I., Zhang, J., Anitha, M. & Patterson, A. D., Feb 1 2019, In : Drug Metabolism and Disposition. 47, 2, p. 86-93 8 p.

Research output: Contribution to journalArticle

Berberine
Bacteria
choloylglycine hydrolase
Metabolomics
Bile Acids and Salts
1 Citation (Scopus)

Biomimetic Separation of Transport and Matrix Functions in Lamellar Block Copolymer Channel-Based Membranes

Lang, C., Ye, D., Song, W., Yao, C., Tu, Y. M., Capparelli, C., Lanasa, J. A., Hickner, M. A., Gomez, E. W., Gomez, E. D., Hickey, III, R. J. & Kumar, M., Jul 23 2019, In : ACS nano. 13, 7, p. 8292-8302 11 p.

Research output: Contribution to journalArticle

biomimetics
Biomimetics
block copolymers
Block copolymers
Aquaporins

Blockade of MCU-Mediated Ca 2+ Uptake Perturbs Lipid Metabolism via PP4-Dependent AMPK Dephosphorylation

Tomar, D., Jaña, F., Dong, Z., Quinn, W. J., Jadiya, P., Breves, S. L., Daw, C. C., Srikantan, S., Santhanam, S., Nemani, N., Carvalho, E., Tripathi, A., Worth, A. M., Zhang, X., Razmpour, R., Seelam, A., Rhode, S., Mehta, A. V., Murray, M., Slade, D. & 12 others, Ramirez, S. H., Mishra, P., Gerhard, G. S., Caplan, J., Norton, L., Sharma, K., Rajan, S., Balciunas, D., Wijesinghe, D. S., Ahima, R. S., Baur, J. A. & Madesh, M., Mar 26 2019, In : Cell Reports. 26, 13, p. 3709-3725.e7

Research output: Contribution to journalArticle

Open Access
AMP-Activated Protein Kinases
Lipid Metabolism
Lipids
Liver
Homeostasis
2 Citations (Scopus)

Brain cholesterol metabolism and Parkinson's disease

Huang, X., Sterling, N. W., Du, G., Sun, D., Stetter, C., Kong, L., Zhu, Y., Neighbors, J., Lewis, M., Chen, H., Hohl, R. & Mailman, R., Mar 1 2019, In : Movement Disorders. 34, 3, p. 386-395 10 p.

Research output: Contribution to journalArticle

Parkinson Disease
Cholesterol
Brain
Odds Ratio
Logistic Models
3 Citations (Scopus)

Cell and Animal Models for Studying Hepatitis B Virus Infection and Drug Development

Hu, J., Lin, Y. Y., Chen, P. J., Watashi, K. & Wakita, T., Jan 1 2019, In : Gastroenterology. 156, 2, p. 338-354 17 p.

Research output: Contribution to journalArticle

Virus Diseases
Hepatitis B virus
Animal Models
Pharmaceutical Preparations
Cell Culture Techniques

Characterization of histone deacetylase expression within in vitro and in vivo bladder cancer model systems

Buckwalter, J. M., Chan, W., Shuman, L., Wildermuth, T., Ellis-Mohl, J., Walter, V., Warrick, J., Wu, X. R., Kaag, M. G., Raman, J. & Degraff, D., May 2 2019, In : International journal of molecular sciences. 20, 10, 2599.

Research output: Contribution to journalArticle

Open Access
Histone Deacetylases
bladder
Polymerase chain reaction
Urinary Bladder Neoplasms
cancer

Characterizing protein-DNA binding event subtypes in ChIP-exo data

Yamada, N., Lai, W., Farrell, N., Pugh, B. F. & Mahony, S. A., Mar 15 2019, In : Bioinformatics. 35, 6, p. 903-913 11 p.

Research output: Contribution to journalArticle

DNA-binding Protein
Chromatin Immunoprecipitation
Chromatin
DNA-Binding Proteins
DNA
3 Citations (Scopus)

Chemically synthesized Secoisolariciresinol diglucoside (LGM2605) improves mitochondrial function in cardiac myocytes and alleviates septic cardiomyopathy

Kokkinaki, D., Hoffman, M., Kalliora, C., Kyriazis, I. D., Maning, J., Lucchese, A. M., Santhanam, S., Tomar, D., Park, J. Y., Wang, H., Yang, X. F., Madesh, M., Lymperopoulos, A., Koch, W. J., Christofidou-Solomidou, M. & Drosatos, K., Feb 1 2019, In : Journal of Molecular and Cellular Cardiology. 127, p. 232-245 14 p.

Research output: Contribution to journalArticle

Cardiomyopathies
Punctures
Cardiac Myocytes
Ligation
Reactive Oxygen Species
1 Citation (Scopus)

Chemical pressure effect on the optical conductivity of the nodal-line semimetals ZrSiY (Y= S,Se,Te) and ZrGeY (Y= S,Te)

Ebad-Allah, J., Afonso, J. F., M., K., Hu, J., Zhu, Y. L., Mao, Z. Q., J., K. & Kuntscher, C. A., 2019, In : Physical Review B. 99, 12

Research output: Contribution to journalArticle

metalloids
pressure effects
conductivity
corrugating
interlayers

Conjugated bile acids attenuate allergen-induced airway inflammation and hyperresposiveness by inhibiting UPR transducers

Nakada, E. M., Bhakta, N. R., Korwin-Mihavics, B. R., Kumar, A., Chamberlain, N., Bruno, S. R., Chapman, D. G., Hoffman, S. M., Daphtary, N., Aliyeva, M., Irvin, C. G., Dixon, A. E., Woodruff, P. G., Amin, S., Poynter, M. E., Desai, D. & Anathy, V., Jan 1 2019, In : JCI Insight. 4, 9, e98101.

Research output: Contribution to journalArticle

Open Access
Unfolded Protein Response
Transducers
Bile Acids and Salts
Allergens
Inflammation

Coordinated Network Changes across the Catalytic Cycle of Alpha Tryptophan Synthase

O'Rourke, K. F., Sahu, D., Bosken, Y. K., D'Amico, R. N., Chang, C. E. A. & Boehr, D. D., Sep 3 2019, In : Structure. 27, 9, p. 1405-1415.e5

Research output: Contribution to journalArticle

Tryptophan Synthase
Proteins
Enzymes
Amino Acids
Molecular Dynamics Simulation

Cross Sectional Study and Risk Factors Analysis of Francisella tularensis in Soil Samples in Punjab Province of Pakistan

Muhammad, J., Rabbani, M., Shabbir, M. Z., Muhammad, K., Ghori, M. T., Chaudhry, H. R., Hassnain, Z. U., Jamil, T., Abbas, T., Chaudhry, M. H., Haisem-Ur-Rasool, M., Ali, M. A., Nisar, M., Kirimanjeswara, G. S. & Jayarao, B. M., Jan 1 2019, In : Frontiers in Cellular and Infection Microbiology. 9, APR, 089.

Research output: Contribution to journalArticle

Open Access
Francisella tularensis
Pakistan
Statistical Factor Analysis
Soil
Cross-Sectional Studies

Cross-talk between N-terminal and C-terminal domains in stromal interaction molecule 2 (STIM2) determines enhanced STIM2 sensitivity

Emrich, S. M., Yoast, R. E., Xin, P., Zhang, X., Pathak, T., Nwokonko, R., Gueguinou, M. F., Subedi, K. P., Zhou, Y., Ambudkar, I. S., Hempel, N., Machaca, K., Gill, D. & Trebak, M., Jan 1 2019, In : Journal of Biological Chemistry. 294, 16, p. 6318-6332 15 p.

Research output: Contribution to journalArticle

Molecules
Chemical activation
Clustered Regularly Interspaced Short Palindromic Repeats
Cell Membrane
Stromal Interaction Molecule 2
1 Citation (Scopus)

Development of Isoselenocyanate Compounds' Syntheses and Biological Applications

Frieben, E. E., Amin, S. & Sharma, A., Jun 13 2019, In : Journal of Medicinal Chemistry. 62, 11, p. 5261-5275 15 p.

Research output: Contribution to journalArticle

Sulfur
Isothiocyanates
Neoplasms
Organoselenium Compounds
Glucosinolates
1 Citation (Scopus)

Device characteristics of long term electronic cigarette users: A follow-up study

Yingst, J., Foulds, J., Veldheer, S. & Du, P., Apr 1 2019, In : Addictive Behaviors. 91, p. 238-243 6 p.

Research output: Contribution to journalArticle

Tobacco Products
Equipment and Supplies
Nicotine
Tobacco
Electronic Cigarettes
3 Citations (Scopus)

Differential YAP expression in glioma cells induces cell competition and promotes tumorigenesis

Liu, Z., Yee, P. P., Wei, Y., Liu, Z., Imamura, Y. & Li, W., Mar 1 2019, In : Journal of Cell Science. 132, 5, jcs225714.

Research output: Contribution to journalArticle

Open Access
Glioma
Carcinogenesis
Neoplasms
Glioblastoma
Growth
2 Citations (Scopus)

Domain topology, stability, and translation speed determine mechanical force generation on the ribosome

Leininger, S. E., Trovato, F., Nissley, D. A. & O'Brien, Jr., E. P., Jan 1 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 12, p. 5523-5532 10 p.

Research output: Contribution to journalArticle

Ribosomes
Proteins
Statistical Models
Proteome
Phenotype

Downregulation of CD73 associates with T cell exhaustion in AML patients

Kong, Y., Jia, B., Zhao, C., Claxton, D., Sharma, A., Annageldiyev, C., Fotos, J., Zeng, H., Paulson, R., Prabhu, K. S. & Zheng, H., Apr 24 2019, In : Journal of Hematology and Oncology. 12, 1, 40.

Research output: Contribution to journalArticle

Open Access
Acute Myeloid Leukemia
Down-Regulation
T-Lymphocytes
Adenosine
Neoplasms

Dual role of a C-terminally truncated isoform of large tumor suppressor kinase 1 in the regulation of hippo signaling and tissue growth

Matsui, Y., Zhang, Y., Paulson, R. & Lai, Z., Jan 1 2019, In : DNA and Cell Biology. 38, 1, p. 91-106 16 p.

Research output: Contribution to journalArticle

Protein Isoforms
Phosphotransferases
Growth
Neoplasms
Drosophila
N'-nitrosonornicotine
Oral Leukoplakia
Tobacco
Tongue
Carcinogens
1 Citation (Scopus)
Open Access
Acute Myeloid Leukemia
T-Lymphocytes
Leukemia
Transcription Factors
Induction Chemotherapy

Evaluating the structural complexity of isomeric bile acids with ion mobility spectrometry

Zheng, X., Smith, F. B., Aly, N. A., Cai, J., Smith, R. D., Patterson, A. D. & Baker, E. S., Jul 19 2019, In : Analytical and Bioanalytical Chemistry. 411, 19, p. 4673-4682 10 p.

Research output: Contribution to journalArticle

Bile Acids and Salts
Spectrometry
Spectrum Analysis
Ions
Isomers
1 Citation (Scopus)

Examination and reconstruction of three ancient endogenous parvovirus capsid protein gene remnants found in rodent genomes

Callaway, H. M., Subramanian, S., Urbina, C. A., Barnard, K. N., Dick, R. A., Bator, C. M., Hafenstein, S., Gifford, R. J. & Parrish, C. R., Mar 1 2019, In : Journal of virology. 93, 6, e01542-18.

Research output: Contribution to journalArticle

Parvovirus
Protoparvovirus
Capsid Proteins
coat proteins
capsid
1 Citation (Scopus)

Extracellular vesicle-dependent effect of RNA-binding protein IGF2BP1 on melanoma metastasis

Ghoshal, A., Rodrigues, L. C., Gowda, C. P., Elcheva, I., Liu, Z., Abraham, T. & Spiegelman, V., May 23 2019, In : Oncogene. 38, 21, p. 4182-4196 15 p.

Research output: Contribution to journalArticle

Insulin-Like Growth Factor Binding Protein 2
RNA-Binding Proteins
Melanoma
Neoplasm Metastasis
Messenger RNA

Fascin Controls Metastatic Colonization and Mitochondrial Oxidative Phosphorylation by Remodeling Mitochondrial Actin Filaments

Lin, S., Huang, C., Gunda, V., Sun, J., Chellappan, S. P., Li, Z., Izumi, V., Fang, B., Koomen, J., Singh, P. K., Hao, J. & Yang, S., Sep 10 2019, In : Cell Reports. 28, 11, p. 2824-2836.e8

Research output: Contribution to journalArticle

Open Access
Oxidative Phosphorylation
Actin Cytoskeleton
Actins
Lung Neoplasms
Physiological Stress

Fendiline Enhances the Cytotoxic Effects of Therapeutic Agents on PDAC Cells by Inhibiting Tumor-Promoting Signaling Events: A Potential Strategy to Combat PDAC

Alhothali, M., Mathew, M., Iyer, G., Lawrence, H. R., Yang, S., Chellappan, S. & Padmanabhan, J., May 16 2019, In : International journal of molecular sciences. 20, 10

Research output: Contribution to journalArticle

Open Access
Fendiline
combat
Therapeutic Uses
Tumors
tumors

Gab2 and Gab3 redundantly suppress colitis by modulating macrophage and CD8+ T-cell activation

Wang, Z., Vaughan, T. Y., Zhu, W., Chen, Y., Fu, G., Medrzycki, M., Nishio, H., Bunting, S. T., Giblin, P. H., Nusrat, A., Parkos, C. A., Wang, D., Wen, R. & Bunting, K. D., Jan 1 2019, In : Frontiers in immunology. 10, MAR, 486.

Research output: Contribution to journalArticle

Open Access
Colitis
Macrophages
T-Lymphocytes
Knockout Mice
Rectal Prolapse

Gdf15 regulates murine stress erythroid progenitor proliferation and the development of the stress erythropoiesis niche

Hao, S., Xiang, J., Wu, D. C., Fraser, J. W., Ruan, B., Cai, J., Patterson, A. D., Lai, Z. & Paulson, R., Jul 23 2019, In : Blood Advances. 3, 14, p. 2205-2217 13 p.

Research output: Contribution to journalArticle

Open Access
Growth Differentiation Factor 15
Erythropoiesis
Erythroid Cells
Monocytes
Homeostasis
4 Citations (Scopus)

Genome-Wide Profiling of Cervical RNA-Binding Proteins Identifies Human Papillomavirus Regulation of RNASEH2A Expression by Viral E7 and E2F1

Xu, J., Liu, H., Yang, Y., Wang, X., Liu, P., Li, Y., Meyers, C., Banerjee, N. S., Wang, H. K., Cam, M., Lu, W., Chow, L. T., Xie, X., Zhu, J. & Zheng, Z. M., Jan 29 2019, In : mBio. 10, 1

Research output: Contribution to journalArticle

RNA-Binding Proteins
Genome
Uterine Cervical Neoplasms
p16 Genes
DNA Replication
2 Citations (Scopus)

Histone deacetylase inhibitor targets CD123/CD47-positive cells and reverse chemoresistance phenotype in acute myeloid leukemia

Yan, B., Chen, Q., Shimada, K., Tang, M., Li, H., Gurumurthy, A., Khoury, J. D., Xu, B., Huang, S. & Qiu, Y., Apr 1 2019, In : Leukemia. 33, 4, p. 931-944 14 p.

Research output: Contribution to journalArticle

Histone Deacetylase Inhibitors
Acute Myeloid Leukemia
Phenotype
Leukemia
Cytarabine
1 Citation (Scopus)

HOX Loci Focused CRISPR/sgRNA Library Screening Identifying Critical CTCF Boundaries

Luo, H., Sobh, A., Vulpe, C. D., Brewer, E., Dovat, S., Qiu, Y. & Huang, S., Mar 31 2019, In : Journal of visualized experiments : JoVE. 145

Research output: Contribution to journalArticle

Clustered Regularly Interspaced Short Palindromic Repeats
Chromatin
Screening
Genes
Gene Expression

Identification of a novel quinoxaline-isoselenourea targeting the STAT3 pathway as a potential melanoma therapeutic

Alcolea, V., Karelia, D. N., Pandey, M. K., Plano, D., Singh, P., Palop, J. A., Amin, S., Sanmartín, C. & Sharma, A., Feb 1 2019, In : International journal of molecular sciences. 20, 3, 521.

Research output: Contribution to journalArticle

quinoxalines
STAT3 Transcription Factor
Quinoxalines
Transcription
Transducers

Identifying A- and P-site locations on ribosome-protected mRNA fragments using Integer Programming

Ahmed, N., Sormanni, P., Ciryam, P., Vendruscolo, M., Dobson, C. M. & O'Brien, Jr., E. P., Dec 1 2019, In : Scientific reports. 9, 1, 6256.

Research output: Contribution to journalArticle

Open Access
Ribosomes
Messenger RNA
Codon
Camellia
Reading Frames

Ikaros tumor suppressor function includes induction of active enhancers and super-enhancers along with pioneering activity

Ding, Y., Zhang, B., Payne, J. L., Song, C., Ge, Z., Gowda, C., Iyer, S., Dhanyamraju, P. K., Dorsam, G., Reeves, M. E., Desai, D., Huang, S., Payne, K. J., Yue, F. & Dovat, S., Jan 1 2019, In : Leukemia.

Research output: Contribution to journalArticle

Open Access
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
T-Lymphocytes
Epigenomics
Chromatin
Cell Differentiation
1 Citation (Scopus)

Imaging elemental events of store-operated Ca2+ entry in invading cancer cells with plasmalemmal targeted sensors

Lu, F., Sun, J., Zheng, Q., Li, J., Hu, Y., Yu, P., He, H., Zhao, Y., Wang, X., Yang, S. & Cheng, H., Mar 1 2019, In : Journal of Cell Science. 132, 6, 224923.

Research output: Contribution to journalArticle

Open Access
Neoplasms
Biosensing Techniques
Calmodulin
Melanoma
Interviews
1 Citation (Scopus)

Increased circulating microparticles in streptozotocin-induced diabetes propagate inflammation contributing to microvascular dysfunction

Feng, Q., Stork, C. J., Xu, S., Yuan, D., Xia, X., LaPenna, K. B., Guo, G., Sun, H., Xu, L., Siedlecki, C., Brundage, K. M., Sheaffer, N., Schell, T. & He, P., Feb 1 2019, In : Journal of Physiology. 597, 3, p. 781-798 18 p.

Research output: Contribution to journalArticle

Experimental Diabetes Mellitus
Inflammation
Microvessels
Phosphatidylserines
Blood Vessels
5 Citations (Scopus)

Induction of store-operated calcium entry (SOCE) suppresses glioblastoma growth by inhibiting the Hippo pathway transcriptional coactivators YAP/TAZ

Liu, Z., Wei, Y., Zhang, L., Yee, P. P., Johnson, M., Zhang, X., Gulley, M., Atkinson, J. M., Trebak, M., Wang, H-G. & Li, W., Jan 3 2019, In : Oncogene. 38, 1, p. 120-139 20 p.

Research output: Contribution to journalArticle

Protein Kinase C beta
Glioblastoma
Amlodipine
Calcium
Growth

Inflammation induces stress erythropoiesis through heme-dependent activation of SPI-C

Bennett, L. F., Liao, C., Quickel, M. D., Yeoh, B. S., Vijay-Kumar, M., Giblin, P. H., Prabhu, K. S. & Paulson, R., Sep 10 2019, In : Science signaling. 12, 598, eaap7336.

Research output: Contribution to journalArticle

Erythropoiesis
Heme
Chemical activation
Inflammation
Toll-Like Receptors

Inhibiting geranylgeranyl diphosphate synthesis reduces nuclear androgen receptor signaling and neuroendocrine differentiation in prostate cancer cell models

Weissenrieder, J. S., Reilly, J. E., Neighbors, J. & Hohl, R., Jan 1 2019, In : Prostate. 79, 1, p. 21-30 10 p.

Research output: Contribution to journalArticle

Androgen Receptors
Cytoplasmic and Nuclear Receptors
Prostatic Neoplasms
Androgens
Prenylation

Inhibition of diverse opportunistic viruses by structurally optimized retrograde trafficking inhibitors

Desai, D., Lauver, M., Ostman, A., Cruz, L., Ferguson, K., Jin, G., Roper, B., Brosius, D., Lukacher, A., Amin, S. & Buchkovich, N., May 1 2019, In : Bioorganic and Medicinal Chemistry. 27, 9, p. 1795-1803 9 p.

Research output: Contribution to journalArticle

Viruses
Polyomavirus
Stem Cell Transplantation
Stem cells
Cytomegalovirus