Research Output 1963 2019

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21 Citations (Scopus)
epigallocatechin
colitis
Colitis
Weight Loss
Digestion
24 Citations (Scopus)

(-)-Xanthatin selectively induces GADD45γ and stimulates caspase-independent cell death in human breast cancer MDA-MB-231 cells

Takeda, S., Matsuo, K., Yaji, K., Okajima-Miyazaki, S., Harada, M., Miyoshi, H., Okamoto, Y., Amamoto, T., Shindo, M., Omiecinski, C. J. & Aramaki, H., Jun 20 2011, In : Chemical research in toxicology. 24, 6, p. 855-865 11 p.

Research output: Contribution to journalArticle

Cell death
Caspases
Cell Death
Breast Neoplasms
Farnesyltranstransferase
16 Citations (Scopus)

(-)-Xanthatin up-regulation of the GADD45γ tumor suppressor gene in MDA-MB-231 breast cancer cells: Role of topoisomerase IIα inhibition and reactive oxygen species

Takeda, S., Noguchi, M., Matsuo, K., Yamaguchi, Y., Kudo, T., Nishimura, H., Okamoto, Y., Amamoto, T., Shindo, M., Omiecinski, C. J. & Aramaki, H., Mar 8 2013, In : Toxicology. 305, p. 1-9 9 p.

Research output: Contribution to journalArticle

Type II DNA Topoisomerase
Tumor Suppressor Genes
DNA Damage
Tumors
Reactive Oxygen Species
8 Citations (Scopus)

[3H]thymidine incorporation in bovine lymphocytes treated with the tumor promoter, 12-O-tetradecanoyl phorobol-13-acetate

Mastro, A. M. & Pepin, K. G., Jan 1 1981, In : Experimental Cell Research. 135, 2, p. 267-276 10 p.

Research output: Contribution to journalArticle

Carcinogens
Thymidine
Acetates
Lymphocytes
Tetradecanoylphorbol Acetate
47 Citations (Scopus)

[60] Fructose-1,6-diphosphatase from Rabbit Liver

Ulm, E. H., Pogell, B. M., deMaine, M. M., Libby, C. B. & Benkovic, S., Jan 1 1975, In : Methods in Enzymology. 42, C, p. 369-374 6 p.

Research output: Contribution to journalArticle

Fructose-Bisphosphatase
Spectrophotometry
Adenosine Monophosphate
Edetic Acid
Chromatography
313 Citations (Scopus)

1,25-Dihydroxycholecalciferol inhibits the progression of arthritis in murine models of human arthritis

Cantorna, M. T-A., Hayes, C. E. & DeLuca, H. F., Jan 1998, In : Journal of Nutrition. 128, 1, p. 68-72 5 p.

Research output: Contribution to journalArticle

calcitriol
Calcitriol
arthritis
Arthritis
animal models
385 Citations (Scopus)

1,25-Dihydroxycholecalciferol prevents and ameliorates symptoms of experimental murine inflammatory bowel disease

Cantorna, M. T-A., Munsick, C., Bemiss, C. & Mahon, B. D., Nov 16 2000, In : Journal of Nutrition. 130, 11, p. 2648-2652 5 p.

Research output: Contribution to journalArticle

calcitriol
Calcitriol
inflammatory bowel disease
vitamin D
Inflammatory Bowel Diseases
223 Citations (Scopus)

1,25-Dihydroxyvitamin D3 is a positive regulator for the two anti- encephalitogenic cytokines TGF-β1 and IL-4

Cantorna, M. T-A., Woodward, W. D., Hayes, C. E. & DeLuca, H. F., Jun 1 1998, In : Journal of Immunology. 160, 11, p. 5314-5319 6 p.

Research output: Contribution to journalArticle

Calcitriol
Interleukin-4
Cytokines
Encephalomyelitis
Lymphocyte Count

1,25-dihydroxyvitamin D3 prolongs graft survival without compromising host resistance to infection or bone mineral density

Cantorna, M. T-A., Hullett, D. A. & DeLuca, H. F., Mar 20 1998, In : FASEB Journal. 12, 5

Research output: Contribution to journalArticle

calcitriol
Transplants
Calcitriol
bone density
Graft Survival
76 Citations (Scopus)

1,25-Dihydroxyvitamin D3 prolongs graft survival without compromising host resistance to infection or bone mineral density

Cantorna, M. T., Hullett, D. A., Redaelli, C., Brandt, C. R., Humpal-Winter, J., Sollinger, H. W. & Deluca, H. F., Oct 15 1998, In : Transplantation. 66, 7, p. 828-831 4 p.

Research output: Contribution to journalArticle

Calcitriol
Graft Survival
Bone Density
Infection
Bone and Bones
576 Citations (Scopus)
Encephalomyelitis
Autoimmune Experimental Encephalomyelitis
Calcitriol
Multiple Sclerosis
Vitamin A Deficiency
71 Citations (Scopus)

1,2-Dihydro-1,2-dihydroxy-5-methylchrysene, a Major Activated Metabolite of the Environmental Carcinogen 5-Methylchrysene

Hecht, S. S., LaVoie, E., Mazzarese, RÜ., Amin, S. & Bedenko, V., Jul 1 1978, In : Cancer Research. 38, 7, p. 2191-2194 4 p.

Research output: Contribution to journalArticle

Environmental Carcinogens
Aroclors
5-methylchrysene
1,2-dihydro-1,2-dihydroxy-5-methylchrysene
Mutagens
24 Citations (Scopus)
Selenomethionine
Androgen Receptors
Prostatic Neoplasms
Phosphatidylinositol 3-Kinase
Androgens
53 Citations (Scopus)

1,4-Phenylenebis(methylene)selenocyanate exerts exceptional chemopreventive activity in rat tongue carcinogenesis

Tanaka, T., Makita, H., Kawabata, K., Mori, H. & El-Bayoumy, K., Sep 1 1997, In : Cancer Research. 57, 17, p. 3644-3648 5 p.

Research output: Contribution to journalArticle

Tongue
Carcinogenesis
4-Nitroquinoline-1-oxide
Selenium
Ornithine Decarboxylase
4 Citations (Scopus)

10-(2-Benzoxazolcarbonyl)-5,10-dideaza-acyclic-5,6,7,8-tetrahydrofolic acid: A potential inhibitor of GAR transformylase and AICAR transformylase

Marsilje, T. H., Hedrick, M. P., Desharnais, J., Capps, K., Tavassoli, A., Zhang, Y., Wilson, I. A., Benkovic, S. & Boger, D. L., Oct 1 2003, In : Bioorganic and Medicinal Chemistry. 11, 20, p. 4503-4509 7 p.

Research output: Contribution to journalArticle

Phosphoribosylaminoimidazolecarboxamide Formyltransferase
Phosphoribosylglycinamide Formyltransferase
Hydroxymethyl and Formyl Transferases
Aminoimidazole Carboxamide
Ketones
16 Citations (Scopus)

10-Formyl-5,10-dideaza-acyclic-5,6,7,8-tetrahydrofolic acid (10-Formyl-DDACTHF): A potent cytotoxic agent acting by selective inhibition of human GAR Tfase and the de novo purine biosynthetic pathway

Marsilje, T. H., Labroli, M. A., Hedrick, M. P., Jin, Q., Desharnais, J., Baker, S. J., Gooljarsingh, L. T., Ramcharan, J., Tavassoli, A., Zhang, Y., Wilson, I. A., Beardsley, G. P., Benkovic, S. J. & Boger, D. L., Jun 24 2002, In : Bioorganic and Medicinal Chemistry. 10, 8, p. 2739-2749 11 p.

Research output: Contribution to journalArticle

Phosphoribosylglycinamide Formyltransferase
Hydroxymethyl and Formyl Transferases
Biosynthetic Pathways
Cytotoxins
Escherichia coli
40 Citations (Scopus)

12(R)-hydroxy-5(Z),8(Z),10(E),14(Z)-eicosatetraenoic acid [12(R)-HETE], an arachidonic acid derivative, is an activator of the aryl hydrocarbon receptor

Chiaro, C. R., Patel, R. D. & Perdew, G. H., Dec 1 2008, In : Molecular Pharmacology. 74, 6, p. 1649-1656 8 p.

Research output: Contribution to journalArticle

12-Hydroxy-5,8,10,14-eicosatetraenoic Acid
Arachidonic Acids
Aryl Hydrocarbon Receptors
Arachidonic Acid
Ligands
29 Citations (Scopus)

15-Deoxy-Δ 12,14 -prostaglandin J 2 inhibits HIV-1 transactivating protein, Tat, through covalent modification

Kalantari, P., Narayan, V., Henderson, A. J. & Prabhu, K. S., Aug 1 2009, In : FASEB Journal. 23, 8, p. 2366-2373 8 p.

Research output: Contribution to journalArticle

tat Gene Products
Transcription
Sulfhydryl Compounds
Prostaglandins
HIV-1
240 Citations (Scopus)

19F magnetic resonance imaging for stem/progenitor cell tracking with multiple unique perfluorocarbon nanobeacons

Partlow, K. C., Chen, J., Brant, J. A., Neubauer, A. M., Meyerrose, T. E., Creer, M., Nolta, J. A., Caruthers, S. D., Lanza, G. M. & Wickline, S. A., Jun 1 2007, In : FASEB Journal. 21, 8, p. 1647-1654 8 p.

Research output: Contribution to journalArticle

Cell Tracking
Fluorocarbons
Magnetic resonance
Stem cells
Stem Cells
2 Citations (Scopus)

2016 Children's Tumor Foundation conference on neurofibromatosis type 1, neurofibromatosis type 2, and schwannomatosis

Fisher, M. J., Belzberg, A. J., de Blank, P., De Raedt, T., Elefteriou, F., Ferner, R. E., Giovannini, M., Harris, G. J., Kalamarides, M., Karajannis, M. A., Kim, A. R., Lázaro, C., Le, L. Q., Li, W., Listernick, R., Martin, S., Morrison, H., Pasmant, E., Ratner, N., Schorry, E. & 7 others, Ullrich, N. J., Viskochil, D., Weiss, B., Widemann, B. C., Zhu, Y., Bakker, A. & Serra, E., May 1 2018, In : American Journal of Medical Genetics, Part A. 176, 5, p. 1258-1269 12 p.

Research output: Contribution to journalArticle

Neurofibromatosis 2
Neurofibromatosis 1
Neurofibromatoses
Neurilemmoma
Plexiform Neurofibroma
6 Citations (Scopus)

22nd Marabou Symposium: The changing faces of vitamin D

James, P., Rosenberg, I., Mangelsdorf, D., DeLuca, H., Mathieu, C., Prentice, A., Meyer, H., Heaney, R., Holick, M., Garza, C., Moan, J., Angelin, B., Pedersen, J., Moskilde, L., Cross, H., Tuohimaa, P., Abrams, S., Campbell, M., Takasu, H., Haussler, M. & 4 others, Sitrin, M., Cantorna, M. T-A., Hernell, O. & Lamberg-Allardt, C., Oct 1 2008, In : Nutrition reviews. 66, SUPPL.2

Research output: Contribution to journalArticle

Vitamin D
6 Citations (Scopus)

3,5,5-trimethyl-hexanoyl-ferrocene diet protects mice from moderate transient acetaminophen-induced hepatotoxicity

Moon, M. S., Kang, B. H., Krzeminski, J., Amin, S., Aliaga, C., Zhu, J., Mcdevitt, E. I., Kocher, S., Richie, J. P. & Isom, H. C., Dec 1 2011, In : Toxicological Sciences. 124, 2, p. 348-358 11 p.

Research output: Contribution to journalArticle

Acetaminophen
Nutrition
Diet
Iron
Liver
4 Citations (Scopus)

3-Deoxyschweinfurthin B Lowers Cholesterol Levels by Decreasing Synthesis and Increasing Export in Cultured Cancer Cell Lines

Kuder, C. H., Weivoda, M. M., Zhang, Y., Zhu, J., Neighbors, J., Wiemer, D. F. & Hohl, R., Dec 1 2015, In : Lipids. 50, 12, p. 1195-1207 13 p.

Research output: Contribution to journalArticle

Cultured Cells
Cholesterol
Cells
Cell Line
Liver
2 Citations (Scopus)

4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone, a Nicotine-derived Carcinogenic Nitrosaminoketone (NNK): Three-dimensional Structure

Katz, A. K., Carrell, H. L., Afshar, C. E., Glusker, J. P., Desai, D. & Amin, S., Jan 1 1999, In : Structural Chemistry. 10, 6, p. 439-443 5 p.

Research output: Contribution to journalArticle

nicotine
Nicotine
Molecules
Dihedral angle
dihedral angle
10 Citations (Scopus)
Butanones
Corn Oil
Fish Oils
Apolipoprotein A-I
Proteome
9 Citations (Scopus)

4-Hydroxy-1-(3-pyridyl)-1-butanone, an indicator for 4-(methylnitrosamino)- 1-(3-pyridyl)-1-butanone-induced DNA damage, is not detected in human pancreatic tissue

Prokopczyk, B., Leder, G., Trushin, N., Cunningham, A. J., Akerkar, S., Pittman, B., Ramadani, M., Straeter, J., Beger, H. G., Henne-Bruns, D. & El-Bayoumy, K., Feb 1 2005, In : Cancer Epidemiology Biomarkers and Prevention. 14, 2, p. 540-541 2 p.

Research output: Contribution to journalArticle

Butanones
Pyridines
Nitrosamines
DNA Adducts
Pancreatic Neoplasms
26 Citations (Scopus)

5, 10-Methylene-5, 6, 7, 8-tetrahydrofolate. Conformation of the Tetrahydropyrazine and Imidazoline Rings†

Poe, M., Jackman, L. M. & Benkovic, S., Jan 1 1979, In : Biochemistry. 18, 24, p. 5527-5530 4 p.

Research output: Contribution to journalArticle

Imidazolines
Conformations
Hydrogen
Imidazolidines
Stereoisomerism
27 Citations (Scopus)

5-Formyl- and 10-Formyl-5,6,7,8-tetrahydrofolate. Conformation of the Tetrahydropyrazine Ring and Formyl Group in Solution

Poe, M. & Benkovic, S., Jan 1 1980, In : Biochemistry. 19, 20, p. 4576-4582 7 p.

Research output: Contribution to journalArticle

Formyltetrahydrofolates
Deuterium
Ion Exchange Chromatography
Folic Acid
Conformations
1 Citation (Scopus)

5 Methylation and demethylation of his tone arg and lys residues in chromatin structure and function

Wang, Y., Dec 1 2006, In : Enzymes. 24, C, p. 123-153 31 p.

Research output: Contribution to journalArticle

Methylation
Histones
Chromatin
Citrulline
Protein Methyltransferases
2 Citations (Scopus)

5′-methylschweinfurthin G reduces chondrosarcoma tumor growth

Stevens, J. W., Meyerholz, D. K., Neighbors, J. D. & Morcuende, J. A., Apr 2018, In : Journal of Orthopaedic Research. 36, 4, p. 1283-1293 11 p.

Research output: Contribution to journalArticle

Chondrosarcoma
Growth
Hyaline Cartilage
Neoplasms
Phenotype
166 Citations (Scopus)

5′-triphosphate-dependent activation of PKR by RNAs with short stem-loops

Nallagatla, S. R., Hwang, J., Toroney, R., Zheng, X., Cameron, C. E. & Bevilacqua, P. C., Nov 30 2007, In : Science. 318, 5855, p. 1455-1458 4 p.

Research output: Contribution to journalArticle

RNA
eIF-2 Kinase
Interferon Type I
Double-Stranded RNA
Interferons
86 Citations (Scopus)

A2B Adenosine Receptor Gene Deletion Attenuates Murine Colitis

Kolachala, V. L., Kumar, M. V., Dalmasso, G., Yang, D., Linden, J., Wang, L., Gewirtz, A., Ravid, K., Merlin, D. & Sitaraman, S. V., Jan 1 2008, In : Gastroenterology. 135, 3, p. 861-870 10 p.

Research output: Contribution to journalArticle

Adenosine A2B Receptors
Gene Deletion
Colitis
Dextran Sulfate
Neutrophils
78 Citations (Scopus)
Oncogene Protein pp60(v-src)
HSP90 Heat-Shock Proteins
Rous sarcoma virus
Heat-Shock Proteins
Viruses

A 50 kDa protein associated with c-raf-1 and pp60v-src is a mammalian homolog of the cell cycle control protein Cdc 37

Wiegand, H., Singh, S. S., Vanden Huevel, J. P., Mitchell, C. & Perdew, G. H., Dec 1 1996, In : FASEB Journal. 10, 3, p. A683

Research output: Contribution to journalArticle

Cell Cycle Proteins
Cell Cycle Checkpoints
Cells
Proteins
Phosphotransferases
71 Citations (Scopus)

A 50 kilodalton protein associated with raf and pp60(v-src) protein kinases is a mammalian homolog of the cell cycle control protein cdc37

Perdew, G. H., Wiegand, H., Vanden Heuvel, J. P., Mitchell, C. & Singh, S. S., Mar 25 1997, In : Biochemistry. 36, 12, p. 3600-3607 8 p.

Research output: Contribution to journalArticle

Oncogene Protein pp60(v-src)
Cell Cycle Proteins
src-Family Kinases
Cell Cycle Checkpoints
Protein Kinases
462 Citations (Scopus)

A barrier nucleosome model for statistical positioning of nucleosomes throughout the yeast genome

Mavrich, T. N., Ioshikhes, I. P., Venters, B. J., Jiang, C., Tomsho, L. P., Qi, J., Schuster, S. C., Albert, I. & Pugh, B. F., Jul 1 2008, In : Genome research. 18, 7, p. 1073-1083 11 p.

Research output: Contribution to journalArticle

Nucleosomes
Statistical Models
Yeasts
Genome
Genetic Promoter Regions
14 Citations (Scopus)

A Barrier-only boundary element delimits the formation of facultative heterochromatin in Drosophila melanogaster and vertebrates

Lin, N., Li, X., Cui, K., Chepelev, I., Tie, F., Liu, B., Li, G., Harte, P., Zhao, K., Huang, S. & Zhou, L., Jul 1 2011, In : Molecular and cellular biology. 31, 13, p. 2729-2741 13 p.

Research output: Contribution to journalArticle

Insulator Elements
Heterochromatin
Drosophila melanogaster
Chromatin
Vertebrates
30 Citations (Scopus)

Abcb11 deficiency induces cholestasis coupled to impaired β-fatty acid oxidation in mice

Zhang, Y., Li, F., Patterson, A. D., Wang, Y., Krausz, K. W., Neale, G., Thomas, S., Nachagari, D., Vogel, P., Vore, M., Gonzalez, F. J. & Schuetz, J. D., Jul 13 2012, In : Journal of Biological Chemistry. 287, 29, p. 24784-24794 11 p.

Research output: Contribution to journalArticle

Cholestasis
Fatty Acids
Liver
Oxidation
Bile Acids and Salts
543 Citations (Scopus)

Aberrant expression of oncogenic and tumor-suppressive microRNAs in cervical cancer is required for cancer cell growth

Wang, X., Tang, S., Le, S. Y., Lu, R., Rader, J. S., Meyers, C. & Zheng, Z. M., Jul 2 2008, In : PloS one. 3, 7, e2557.

Research output: Contribution to journalArticle

uterine cervical neoplasms
Cell growth
MicroRNAs
microRNA
Uterine Cervical Neoplasms
147 Citations (Scopus)

Aberrant lipid metabolism in hepatocellular carcinoma revealed by plasma metabolomics and lipid profiling

Patterson, A. D., Maurhofer, O., Beyoǧlu, D., Lanz, C., Krausz, K. W., Pabst, T., Gonzalez, F. J., Dufour, J. F. & Idle, J. R., Nov 1 2011, In : Cancer Research. 71, 21, p. 6590-6600 11 p.

Research output: Contribution to journalArticle

Metabolomics
Lipid Metabolism
Hepatocellular Carcinoma
Lipids
Liquid Chromatography
28 Citations (Scopus)

Aberrant TAL1 activation is mediated by an interchromosomal interaction in human T-cell acute lymphoblastic leukemia

Patel, B., Kang, Y., Cui, K., Litt, M., Riberio, M. S. J., Deng, C., Salz, T., Casada, S., Fu, X., Qiu, Y., Zhao, K. & Huang, S., Feb 1 2014, In : Leukemia. 28, 2, p. 349-361 13 p.

Research output: Contribution to journalArticle

Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
Chromatin
T-Cell Leukemia
Erythroid Cells
Oncogenes
42 Citations (Scopus)

ABIN1 protein cooperates with TAX1BP1 and A20 proteins to inhibit antiviral signaling

Gao, L., Coope, H., Grant, S., Averil, M., Ley, S. C. & Harhaj, E., Oct 21 2011, In : Journal of Biological Chemistry. 286, 42, p. 36592-36602 11 p.

Research output: Contribution to journalArticle

Neurofibromin 1
Virus Diseases
Viruses
Poly I-C
Antiviral Agents
20 Citations (Scopus)

Abl family tyrosine kinases regulate sialylated ganglioside receptors for polyomavirus

Swimm, A. I., Bornmann, W., Jiang, M., Imperiale, M. J., Lukacher, A. & Kalman, D., May 1 2010, In : Journal of virology. 84, 9, p. 4243-4251 9 p.

Research output: Contribution to journalArticle

Polyomavirus
gangliosides
Protein-Tyrosine Kinases
tyrosine
phosphotransferases (kinases)
89 Citations (Scopus)

A broad-spectrum microbicide with virucidal activity against sexually transmitted viruses

Howett, M. K., Neely, E. B., Christensen, N., Wigdahl, B., Krebs, F. C., Malamud, D., Patrick, S. D., Pickel, M. D., Welsh, P. A., Reed, C. A., Ward, M. G., Budgeon, L. R. & Kreider, J. W., Feb 1 1999, In : Antimicrobial agents and chemotherapy. 43, 2, p. 314-321 8 p.

Research output: Contribution to journalArticle

Anti-Infective Agents
Sodium Dodecyl Sulfate
Surface-Active Agents
Viruses
Nonoxynol
10 Citations (Scopus)

Absence of enantioselectivity in the pharmacodynamics of P450 2B induction by 5‐ethyl‐5‐phenylhydantoin in the male rat liver or in cultured rat hepatocytes

Nims, R. W., Sidhu, J. S., Thomas, P. E., Mellini, D. W., Nelson, V. C., Omiecinski, C. J. & Lubet, R. A., Jan 1 1994, In : Journal of Biochemical Toxicology. 9, 6, p. 279-288 10 p.

Research output: Contribution to journalArticle

Pharmacodynamics
Enantioselectivity
Liver
Cytochrome P-450 Enzyme System
Rats
38 Citations (Scopus)

Absolute configuration of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol formed metabolically from 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone

Hecht, S. S., Spratt, T. E. & Trushin, N., Sep 1 1997, In : Carcinogenesis. 18, 9, p. 1851-1854 4 p.

Research output: Contribution to journalArticle

Carbamates
Glucuronides
Esters
Erythrocebus patas
Isocyanates

Abstracts, division of biological chemistry, 194th national meeting of the american chemical society, august 30-september 4, 1987

Benkovic, S., Peisach, J., Gorenstein, D. G. & Poulter, C. D., Jan 1 1987, In : Biochemistry. 26, 13, p. 4157-4178 22 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

A calcium/cAMP signaling loop at the ORAI1 mouth drives channel inactivation to shape NFAT induction

Zhang, X., Pathak, T., Yoast, R., Emrich, S., Xin, P., Nwokonko, R. M., Johnson, M., Wu, S., Delierneux, C., Gueguinou, M., Hempel, N., Putney, J. W., Gill, D. L. & Trebak, M., Dec 1 2019, In : Nature communications. 10, 1, 1971.

Research output: Contribution to journalArticle

Open Access
Calcium Signaling
mouth
deactivation
Mouth
calcium
133 Citations (Scopus)

A canonical promoter organization of the transcription machinery and its regulators in the Saccharomyces genome

Venters, B. J. & Pugh, B. F., Mar 1 2009, In : Genome research. 19, 3, p. 360-371 12 p.

Research output: Contribution to journalArticle

Saccharomyces
Nucleosomes
Genetic Promoter Regions
Genome
Regulator Genes
25 Citations (Scopus)

A cascade cyclization approach to schweinfurthin B

Treadwell, E. M., Neighbors, J. & Wiemer, D. F., Oct 17 2002, In : Organic Letters. 4, 21, p. 3639-3642 4 p.

Research output: Contribution to journalArticle

Stereochemistry
Cyclization
stereochemistry
Biological Products
cascades