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26 Scopus citations

(-)-Xanthatin selectively induces GADD45γ and stimulates caspase-independent cell death in human breast cancer MDA-MB-231 cells

Takeda, S., Matsuo, K., Yaji, K., Okajima-Miyazaki, S., Harada, M., Miyoshi, H., Okamoto, Y., Amamoto, T., Shindo, M., Omiecinski, C. J. & Aramaki, H., Jun 20 2011, In : Chemical research in toxicology. 24, 6, p. 855-865 11 p.

Research output: Contribution to journalArticle

26 Scopus citations

(-)-Xanthatin up-regulation of the GADD45γ tumor suppressor gene in MDA-MB-231 breast cancer cells: Role of topoisomerase IIα inhibition and reactive oxygen species

Takeda, S., Noguchi, M., Matsuo, K., Yamaguchi, Y., Kudo, T., Nishimura, H., Okamoto, Y., Amamoto, T., Shindo, M., Omiecinski, C. J. & Aramaki, H., Mar 8 2013, In : Toxicology. 305, p. 1-9 9 p.

Research output: Contribution to journalArticle

17 Scopus citations

[3H]thymidine incorporation in bovine lymphocytes treated with the tumor promoter, 12-O-tetradecanoyl phorobol-13-acetate

Mastro, A. M. & Pepin, K. G., Oct 1981, In : Experimental Cell Research. 135, 2, p. 267-276 10 p.

Research output: Contribution to journalArticle

8 Scopus citations

1,25-Dihydroxycholecalciferol inhibits the progression of arthritis in murine models of human arthritis

Cantorna, M. T., Hayes, C. E. & DeLuca, H. F., Jan 1 1998, In : Journal of Nutrition. 128, 1, p. 68-72 5 p.

Research output: Contribution to journalArticle

314 Scopus citations

1,25-Dihydroxycholecalciferol prevents and ameliorates symptoms of experimental murine inflammatory bowel disease

Cantorna, M. T-A., Munsick, C., Bemiss, C. & Mahon, B. D., Nov 16 2000, In : Journal of Nutrition. 130, 11, p. 2648-2652 5 p.

Research output: Contribution to journalArticle

395 Scopus citations

1,25-Dihydroxyvitamin D3 is a positive regulator for the two anti- encephalitogenic cytokines TGF-β1 and IL-4

Cantorna, M. T-A., Woodward, W. D., Hayes, C. E. & DeLuca, H. F., Jun 1 1998, In : Journal of Immunology. 160, 11, p. 5314-5319 6 p.

Research output: Contribution to journalArticle

227 Scopus citations

1,25-dihydroxyvitamin D3 prolongs graft survival without compromising host resistance to infection or bone mineral density

Cantorna, M. T-A., Hullett, D. A. & DeLuca, H. F., Mar 20 1998, In : FASEB Journal. 12, 5

Research output: Contribution to journalArticle

1,25-Dihydroxyvitamin D3 prolongs graft survival without compromising host resistance to infection or bone mineral density

Cantorna, M. T., Hullett, D. A., Redaelli, C., Brandt, C. R., Humpal-Winter, J., Sollinger, H. W. & Deluca, H. F., Oct 15 1998, In : Transplantation. 66, 7, p. 828-831 4 p.

Research output: Contribution to journalArticle

78 Scopus citations
583 Scopus citations

1,2-Dihydro-1,2-dihydroxy-5-methylchrysene, a Major Activated Metabolite of the Environmental Carcinogen 5-Methylchrysene

Hecht, S. S., LaVoie, E., Mazzarese, RÜ., Amin, S. & Bedenko, V., Jul 1 1978, In : Cancer Research. 38, 7, p. 2191-2194 4 p.

Research output: Contribution to journalArticle

71 Scopus citations
26 Scopus citations

1,4-Phenylenebis(methylene)selenocyanate exerts exceptional chemopreventive activity in rat tongue carcinogenesis

Tanaka, T., Makita, H., Kawabata, K., Mori, H. & El-Bayoumy, K., Sep 1 1997, In : Cancer Research. 57, 17, p. 3644-3648 5 p.

Research output: Contribution to journalArticle

53 Scopus citations

10-(2-Benzoxazolcarbonyl)-5,10-dideaza-acyclic-5,6,7,8-tetrahydrofolic acid: A potential inhibitor of GAR transformylase and AICAR transformylase

Marsilje, T. H., Hedrick, M. P., Desharnais, J., Capps, K., Tavassoli, A., Zhang, Y., Wilson, I. A., Benkovic, S. J. & Boger, D. L., Oct 1 2003, In : Bioorganic and Medicinal Chemistry. 11, 20, p. 4503-4509 7 p.

Research output: Contribution to journalArticle

4 Scopus citations

10-Formyl-5,10-dideaza-acyclic-5,6,7,8-tetrahydrofolic acid (10-Formyl-DDACTHF): A potent cytotoxic agent acting by selective inhibition of human GAR Tfase and the de novo purine biosynthetic pathway

Marsilje, T. H., Labroli, M. A., Hedrick, M. P., Jin, Q., Desharnais, J., Baker, S. J., Gooljarsingh, L. T., Ramcharan, J., Tavassoli, A., Zhang, Y., Wilson, I. A., Beardsley, G. P., Benkovic, S. J. & Boger, D. L., Jun 24 2002, In : Bioorganic and Medicinal Chemistry. 10, 8, p. 2739-2749 11 p.

Research output: Contribution to journalArticle

16 Scopus citations

12(R)-hydroxy-5(Z),8(Z),10(E),14(Z)-eicosatetraenoic acid [12(R)-HETE], an arachidonic acid derivative, is an activator of the aryl hydrocarbon receptor

Chiaro, C. R., Patel, R. D. & Perdew, G. H., Dec 1 2008, In : Molecular Pharmacology. 74, 6, p. 1649-1656 8 p.

Research output: Contribution to journalArticle

42 Scopus citations

15-Deoxy-Δ12,14-prostaglandin J2 inhibits HIV-1 transactivating protein, Tat, through covalent modification

Kalantari, P., Narayan, V., Henderson, A. J. & Prabhu, K. S., Aug 1 2009, In : FASEB Journal. 23, 8, p. 2366-2373 8 p.

Research output: Contribution to journalArticle

30 Scopus citations

19F magnetic resonance imaging for stem/progenitor cell tracking with multiple unique perfluorocarbon nanobeacons

Partlow, K. C., Chen, J., Brant, J. A., Neubauer, A. M., Meyerrose, T. E., Creer, M. H., Nolta, J. A., Caruthers, S. D., Lanza, G. M. & Wickline, S. A., Jun 1 2007, In : FASEB Journal. 21, 8, p. 1647-1654 8 p.

Research output: Contribution to journalArticle

244 Scopus citations

2016 Children's Tumor Foundation conference on neurofibromatosis type 1, neurofibromatosis type 2, and schwannomatosis

Fisher, M. J., Belzberg, A. J., de Blank, P., De Raedt, T., Elefteriou, F., Ferner, R. E., Giovannini, M., Harris, G. J., Kalamarides, M., Karajannis, M. A., Kim, A. R., Lázaro, C., Le, L. Q., Li, W., Listernick, R., Martin, S., Morrison, H., Pasmant, E., Ratner, N., Schorry, E. & 7 others, Ullrich, N. J., Viskochil, D., Weiss, B., Widemann, B. C., Zhu, Y., Bakker, A. & Serra, E., May 2018, In : American Journal of Medical Genetics, Part A. 176, 5, p. 1258-1269 12 p.

Research output: Contribution to journalArticle

2 Scopus citations

22nd Marabou Symposium: The changing faces of vitamin D

James, P., Rosenberg, I., Mangelsdorf, D., DeLuca, H., Mathieu, C., Prentice, A., Meyer, H., Heaney, R., Holick, M., Garza, C., Moan, J., Angelin, B., Pedersen, J., Moskilde, L., Cross, H., Tuohimaa, P., Abrams, S., Campbell, M., Takasu, H., Haussler, M. & 4 others, Sitrin, M., Cantorna, M., Hernell, O. & Lamberg-Allardt, C., Oct 1 2008, In : Nutrition reviews. 66, SUPPL.2, p. S195-S212

Research output: Contribution to journalArticle

6 Scopus citations

2-C-methylated nucleotides terminate virus RNA synthesis by preventing active site closure of the viral RNA-dependent RNA polymerase

Boehr, A. K., Arnold, J. J., Oh, H. S., Cameron, C. E. & Boehr, D. D., Jan 1 2019, In : Journal of Biological Chemistry. 294, 45, p. 16897-16907 11 p.

Research output: Contribution to journalArticle

3,5,5-trimethyl-hexanoyl-ferrocene diet protects mice from moderate transient acetaminophen-induced hepatotoxicity

Moon, M. S., Kang, B. H., Krzeminski, J., Amin, S., Aliaga, C., Zhu, J., Mcdevitt, E. I., Kocher, S., Richie, J. P. & Isom, H. C., Dec 1 2011, In : Toxicological Sciences. 124, 2, p. 348-358 11 p.

Research output: Contribution to journalArticle

6 Scopus citations

3-Deoxyschweinfurthin B Lowers Cholesterol Levels by Decreasing Synthesis and Increasing Export in Cultured Cancer Cell Lines

Kuder, C. H., Weivoda, M. M., Zhang, Y., Zhu, J., Neighbors, J. D., Wiemer, D. F. & Hohl, R. J., Dec 1 2015, In : Lipids. 50, 12, p. 1195-1207 13 p.

Research output: Contribution to journalArticle

4 Scopus citations

4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone, a Nicotine-derived Carcinogenic Nitrosaminoketone (NNK): Three-dimensional Structure

Katz, A. K., Carrell, H. L., Afshar, C. E., Glusker, J. P., Desai, D. & Amin, S., Jan 1 1999, In : Structural Chemistry. 10, 6, p. 439-443 5 p.

Research output: Contribution to journalArticle

2 Scopus citations
10 Scopus citations

4-Hydroxy-1-(3-pyridyl)-1-butanone, an indicator for 4-(methylnitrosamino)- 1-(3-pyridyl)-1-butanone-induced DNA damage, is not detected in human pancreatic tissue

Prokopczyk, B., Leder, G., Trushin, N., Cunningham, A. J., Akerkar, S., Pittman, B., Ramadani, M., Straeter, J., Beger, H. G., Henne-Bruns, D. & El-Bayoumy, K., Feb 1 2005, In : Cancer Epidemiology Biomarkers and Prevention. 14, 2, p. 540-541 2 p.

Research output: Contribution to journalArticle

9 Scopus citations

5 Methylation and demethylation of his tone arg and lys residues in chromatin structure and function

Wang, Y., Dec 1 2006, In : Enzymes. 24, C, p. 123-153 31 p.

Research output: Contribution to journalArticle

1 Scopus citations

5′-methylschweinfurthin G reduces chondrosarcoma tumor growth

Stevens, J. W., Meyerholz, D. K., Neighbors, J. D. & Morcuende, J. A., Apr 2018, In : Journal of Orthopaedic Research. 36, 4, p. 1283-1293 11 p.

Research output: Contribution to journalArticle

2 Scopus citations

5′-triphosphate-dependent activation of PKR by RNAs with short stem-loops

Nallagatla, S. R., Hwang, J., Toroney, R., Zheng, X., Cameron, C. E. & Bevilacqua, P. C., Nov 30 2007, In : Science. 318, 5855, p. 1455-1458 4 p.

Research output: Contribution to journalArticle

167 Scopus citations

A2B Adenosine Receptor Gene Deletion Attenuates Murine Colitis

Kolachala, V. L., Vijay-Kumar, M., Dalmasso, G., Yang, D., Linden, J., Wang, L., Gewirtz, A., Ravid, K., Merlin, D. & Sitaraman, S. V., Sep 2008, In : Gastroenterology. 135, 3, p. 861-870 10 p.

Research output: Contribution to journalArticle

86 Scopus citations
78 Scopus citations

A 50 kDa protein associated with c-raf-1 and pp60v-src is a mammalian homolog of the cell cycle control protein Cdc 37

Wiegand, H., Singh, S. S., Vanden Huevel, J. P., Mitchell, C. & Perdew, G. H., Dec 1 1996, In : FASEB Journal. 10, 3, p. A683

Research output: Contribution to journalArticle

A 50 kilodalton protein associated with raf and pp60(v-src) protein kinases is a mammalian homolog of the cell cycle control protein cdc37

Perdew, G. H., Wiegand, H., Vanden Heuvel, J. P., Mitchell, C. & Singh, S. S., Mar 25 1997, In : Biochemistry. 36, 12, p. 3600-3607 8 p.

Research output: Contribution to journalArticle

71 Scopus citations

A barrier nucleosome model for statistical positioning of nucleosomes throughout the yeast genome

Mavrich, T. N., Ioshikhes, I. P., Venters, B. J., Jiang, C., Tomsho, L. P., Qi, J., Schuster, S. C., Albert, I. & Pugh, B. F., Jul 1 2008, In : Genome research. 18, 7, p. 1073-1083 11 p.

Research output: Contribution to journalArticle

477 Scopus citations

A Barrier-only boundary element delimits the formation of facultative heterochromatin in Drosophila melanogaster and vertebrates

Lin, N., Li, X., Cui, K., Chepelev, I., Tie, F., Liu, B., Li, G., Harte, P., Zhao, K., Huang, S. & Zhou, L., Jul 1 2011, In : Molecular and cellular biology. 31, 13, p. 2729-2741 13 p.

Research output: Contribution to journalArticle

14 Scopus citations

Abcb11 deficiency induces cholestasis coupled to impaired β-fatty acid oxidation in mice

Zhang, Y., Li, F., Patterson, A. D., Wang, Y., Krausz, K. W., Neale, G., Thomas, S., Nachagari, D., Vogel, P., Vore, M., Gonzalez, F. J. & Schuetz, J. D., Jul 13 2012, In : Journal of Biological Chemistry. 287, 29, p. 24784-24794 11 p.

Research output: Contribution to journalArticle

32 Scopus citations

Aberrant expression of oncogenic and tumor-suppressive microRNAs in cervical cancer is required for cancer cell growth

Wang, X., Tang, S., Le, S. Y., Lu, R., Rader, J. S., Meyers, C. & Zheng, Z. M., Jul 2 2008, In : PloS one. 3, 7, e2557.

Research output: Contribution to journalArticle

557 Scopus citations

Aberrant lipid metabolism in hepatocellular carcinoma revealed by plasma metabolomics and lipid profiling

Patterson, A. D., Maurhofer, O., Beyoǧlu, D., Lanz, C., Krausz, K. W., Pabst, T., Gonzalez, F. J., Dufour, J. F. & Idle, J. R., Nov 1 2011, In : Cancer Research. 71, 21, p. 6590-6600 11 p.

Research output: Contribution to journalArticle

159 Scopus citations

Aberrant TAL1 activation is mediated by an interchromosomal interaction in human T-cell acute lymphoblastic leukemia

Patel, B., Kang, Y., Cui, K., Litt, M., Riberio, M. S. J., Deng, C., Salz, T., Casada, S., Fu, X., Qiu, Y., Zhao, K. & Huang, S., Feb 1 2014, In : Leukemia. 28, 2, p. 349-361 13 p.

Research output: Contribution to journalArticle

29 Scopus citations

ABIN1 protein cooperates with TAX1BP1 and A20 proteins to inhibit antiviral signaling

Gao, L., Coope, H., Grant, S., Averil, M., Ley, S. C. & Harhaj, E. W., Oct 21 2011, In : Journal of Biological Chemistry. 286, 42, p. 36592-36602 11 p.

Research output: Contribution to journalArticle

43 Scopus citations

Abl family tyrosine kinases regulate sialylated ganglioside receptors for polyomavirus

Swimm, A. I., Bornmann, W., Jiang, M., Imperiale, M. J., Lukacher, A. E. & Kalman, D., May 1 2010, In : Journal of virology. 84, 9, p. 4243-4251 9 p.

Research output: Contribution to journalArticle

20 Scopus citations

A broad-spectrum microbicide with virucidal activity against sexually transmitted viruses

Howett, M. K., Neely, E. B., Christensen, N., Wigdahl, B., Krebs, F. C., Malamud, D., Patrick, S. D., Pickel, M. D., Welsh, P. A., Reed, C. A., Ward, M. G., Budgeon, L. R. & Kreider, J. W., Feb 1 1999, In : Antimicrobial agents and chemotherapy. 43, 2, p. 314-321 8 p.

Research output: Contribution to journalArticle

91 Scopus citations

Absence of enantioselectivity in the pharmacodynamics of P450 2B induction by 5‐ethyl‐5‐phenylhydantoin in the male rat liver or in cultured rat hepatocytes

Nims, R. W., Sidhu, J. S., Thomas, P. E., Mellini, D. W., Nelson, V. C., Omiecinski, C. J. & Lubet, R. A., Jan 1 1994, In : Journal of Biochemical Toxicology. 9, 6, p. 279-288 10 p.

Research output: Contribution to journalArticle

10 Scopus citations

Absolute configuration of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol formed metabolically from 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone

Hecht, S. S., Spratt, T. E. & Trushin, N., Sep 1 1997, In : Carcinogenesis. 18, 9, p. 1851-1854 4 p.

Research output: Contribution to journalArticle

39 Scopus citations

Abstracts, division of biological chemistry, 194th national meeting of the american chemical society, august 30-september 4, 1987

Benkovic, S., Peisach, J., Gorenstein, D. G. & Poulter, C. D., Jan 1 1987, In : Biochemistry. 26, 13, p. 4157-4178 22 p.

Research output: Contribution to journalArticle

Abstracts of Presentations at the Association of Clinical Scientists 139th Meeting Hershey, PA, May 15-18, 2019

Donaldson, K., Buchanich, J. M., Grigson, P. S., Deneke, E., Vrana, K. E., Sacks, D. B., Kuehn, G. J., Cardamone, D., Pesce, A., Smiley, S., Nickley, J., Krock, K., Thomas, R., Wilkerson, M. L., Farag, H. A., Challa, S. R., Tice, A. M., Wolk, D. M., Prichard, J., Grant, M. L. & 102 others, Regmi, S., Kerbacher, B., Quinton, L. E., Tice, A. M., Olson, J., Haynes, A., Yu, E., McCully, K. S., Assi, J., Wong, M., Zarrin-Khameh, N., Nifong, T. P., Hawker, C. D., Carlton, G. T., Rivera, J. M., Foulis, P. R., Zuraw, A., Morlote, D., Peker, D., Reddy, V., Harada, S., Crutchfield, C., Zander, D., Barbhuiya, M. A., Pederson, E. C., Straub, M. L., Scott, S. C., Neibauer, T. L., Salter, W. F., Creer, M. H., Zhu, Y., Bornhorst, J. A., Theobald, J. P., Algeciras-Schimnich, A., Cao, L., Knox, J., Hardy, R., Texas, H. J., McGuire, M. F., Hunter, R. L., Brown, R. E., Hicks, J., Cai, Z., Brown, R. E., Ali, Y., Cheng, K. C., Katz, S. R., Ding, Y., Vanselow, D. J., Yakovlev, M. A., Lin, A. Y., Clark, D. P., Vargas, P., Xin, X., Copper, J. E., Canfield, V. A., Ang, K. C., Wang, Y., Xiao, X., De Carlo, F., van Rossum, D. B., La Rivière, P. J., Newell, J., Hossler, C., Roche, M., Warrick, J., Phaeton, R., Kesterson, J., Myers, C., Barrios, R., Mintz, P., Robyak, K., Hamilton, C., McGhee, P., Pederson, C., Straub, M., Scott, S., Neibauer, T., Salter, W., Robyak, K., Singh, N., Morlote, D., Vnencak-Jones, C., Yemelyanova, A., Harada, S., Shah, M., Moghadamtousi, S. Z., Lan, C., Duose, D., Hu, P., Esquenazi, Y., Luthra, R., Ballester, L. Y., Koenig, A. N., Liu, C. G., Zhang, J., Kalia, A., Al-Habib, A., Van Arsdall, M., Dhingra, S., Patel, K. & Tatevian, N., May 1 2019, In : Annals of clinical and laboratory science. 49, 3, p. 403-416 14 p.

Research output: Contribution to journalArticle

A calcium/cAMP signaling loop at the ORAI1 mouth drives channel inactivation to shape NFAT induction

Zhang, X., Pathak, T., Yoast, R., Emrich, S., Xin, P., Nwokonko, R. M., Johnson, M., Wu, S., Delierneux, C., Gueguinou, M., Hempel, N., Putney, J. W., Gill, D. L. & Trebak, M., Dec 1 2019, In : Nature communications. 10, 1, 1971.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

A canonical promoter organization of the transcription machinery and its regulators in the Saccharomyces genome

Venters, B. J. & Pugh, B. F., Mar 1 2009, In : Genome research. 19, 3, p. 360-371 12 p.

Research output: Contribution to journalArticle

136 Scopus citations

A cascade cyclization approach to schweinfurthin B

Treadwell, E. M., Neighbors, J. & Wiemer, D. F., Oct 17 2002, In : Organic Letters. 4, 21, p. 3639-3642 4 p.

Research output: Contribution to journalArticle

25 Scopus citations

A catalytic antibody uses a multistep kinetic sequence.

Benkovic, S., Adams, J., Janda, K. D. & Lerner, R. A., Jan 1 1991, In : Ciba Foundation symposium. 159

Research output: Contribution to journalArticle