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X-ray Crystal Structures of Escherichia coli RNA Polymerase with Switch Region Binding Inhibitors Enable Rational Design of Squaramides with an Improved Fraction Unbound to Human Plasma Protein

Molodtsov, V., Fleming, P. R., Eyermann, C. J., Ferguson, A. D., Foulk, M. A., McKinney, D. C., Masse, C. E., Buurman, E. T. & Murakami, K. S., Apr 9 2015, In : Journal of Medicinal Chemistry. 58, 7, p. 3156-3171 16 p.

Research output: Contribution to journalArticle

18 Scopus citations

X-ray crystal structures of the Escherichia coli RNA polymerase in complex with benzoxazinorifamycins

Molodtsov, V., Nawarathne, I. N., Scharf, N. T., Kirchhoff, P. D., Showalter, H. D. H., Garcia, G. A. & Murakami, K. S., Jun 13 2013, In : Journal of Medicinal Chemistry. 56, 11, p. 4758-4763 6 p.

Research output: Contribution to journalArticle

32 Scopus citations

XSWR-C and INO80 chromatin remodelers recognize nucleosome-free regions near +1 nucleosomes

Yen, K., Vinayachandran, V. & Pugh, B. F., Sep 12 2013, In : Cell. 154, 6, 1 p.

Research output: Contribution to journalArticle

104 Scopus citations

Yap1 promotes proliferation of transiently amplifying stress erythroid progenitors during erythroid regeneration

Hao, S., Matsui, Y., Lai, Z. C. & Paulson, R. F., Dec 2019, In : Experimental Hematology. 80, p. 42-54.e4

Research output: Contribution to journalArticle

YAP1 subgroup supratentorial ependymoma requires TEAD and nuclear factor I-mediated transcriptional programmes for tumorigenesis

Pajtler, K. W., Wei, Y., Okonechnikov, K., Silva, P. B. G., Vouri, M., Zhang, L., Brabetz, S., Sieber, L., Gulley, M., Mauermann, M., Wedig, T., Mack, N., Imamura Kawasawa, Y., Sharma, T., Zuckermann, M., Andreiuolo, F., Holland, E., Maass, K., Körkel-Qu, H., Liu, H. K. & 13 others, Sahm, F., Capper, D., Bunt, J., Richards, L. J., Jones, D. T. W., Korshunov, A., Chavez, L., Lichter, P., Hoshino, M., Pfister, S. M., Kool, M., Li, W. & Kawauchi, D., Dec 1 2019, In : Nature communications. 10, 1, 3914.

Research output: Contribution to journalArticle

Open Access

Yeast DNA polymerase η makes functional contacts with the DNA minor groove only at the incoming nucleoside triphosphate

Washington, M. T., Wolfle, W. T., Spratt, T. E., Prakash, L. & Prakash, S., Apr 29 2003, In : Proceedings of the National Academy of Sciences of the United States of America. 100, 9, p. 5113-5118 6 p.

Research output: Contribution to journalArticle

37 Scopus citations

Δ 12-prostaglandin J 3, an omega-3 fatty acid-derived metabolite, selectively ablates leukemia stem cells in mice

Hegde, S., Kaushal, N., Ravindra, K. C., Chiaro, C., Hafer, K. T., Gandhi, U. H., Thompson, J. T., Van Den Heuvel, J. P., Kennett, M. J., Hankey, P., Paulson, R. F. & Prabhu, K. S., Dec 22 2011, In : Blood. 118, 26, p. 6909-6919 11 p.

Research output: Contribution to journalArticle

46 Scopus citations

Δ9-tetrahydrocannabinol disrupts estrogen-signaling through up-regulation of estrogen receptor β (ERβ)

Takeda, S., Yoshida, K., Nishimura, H., Harada, M., Okajima, S., Miyoshi, H., Okamoto, Y., Amamoto, T., Watanabe, K., Omiecinski, C. J. & Aramaki, H., Jul 15 2013, In : Chemical research in toxicology. 26, 7, p. 1073-1079 7 p.

Research output: Contribution to journalArticle

20 Scopus citations

αchymotrypsin catalyzed hydrolysis of n-benzoyl-l-tyrosine ethyl ester anchored in βcyclodextrin

Kumble, S. P. & Ramadoss, C. S., Jan 1 1995, In : Biocatalysis and Biotransformation. 12, 4, p. 281-291 11 p.

Research output: Contribution to journalArticle

8 Scopus citations

α-Substituted β-Lactams Via A Convenient Annelation Of Imines

Manhas, M. S., Lai, B., Amin, S. & Bose, A. K., Jan 1 1976, In : Synthetic Communications. 6, 6, p. 435-441 7 p.

Research output: Contribution to journalArticle

25 Scopus citations

β2-microglobulin knockout mice are highly susceptible to polyoma virus tumorigenesis

Drake, D. R. & Lukacher, A. E., Dec 5 1998, In : Virology. 252, 1, p. 275-284 10 p.

Research output: Contribution to journalArticle

36 Scopus citations

β-escin inhibits NNK-induced lung adenocarcinoma and ALDH1A1 and RhoA/Rock expression in A/J mice and growth of H460 human lung cancer cells

Patlolla, J. M. R., Qian, L., Biddick, L., Zhang, Y., Desai, D., Amin, S., Lightfoot, S. & Rao, C. V., Oct 1 2013, In : Cancer Prevention Research. 6, 10, p. 1140-1149 10 p.

Research output: Contribution to journalArticle

15 Scopus citations

δ9-THC modulation of fatty acid 2-hydroxylase (FA2H) gene expression: Possible involvement of induced levels of PPARα in MDA-MB-231 breast cancer cells

Takeda, S., Ikeda, E., Su, S., Harada, M., Okazaki, H., Yoshioka, Y., Nishimura, H., Ishii, H., Kakizoe, K., Taniguchi, A., Tokuyasu, M., Himeno, T., Watanabe, K., Omiecinski, C. J. & Aramaki, H., Dec 4 2014, In : Toxicology. 326, p. 18-24 7 p.

Research output: Contribution to journalArticle

19 Scopus citations
26 Scopus citations