Research Output 1963 2020

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1993
8 Citations (Scopus)

Influence of periconceptional zinc deficiency on embryonic plasma membrane function in mice

Peters, J. M., Wiley, L. M., Zidenberg‐Cherr, S. & Keen, C. L., 1993, In : Teratogenesis, Carcinogenesis, and Mutagenesis. 13, 1, p. 15-21 7 p.

Research output: Contribution to journalArticle

Cell membranes
Zinc
Sodium
Cell Membrane
Embryonic Structures
59 Citations (Scopus)
Organoselenium Compounds
Lung
Selenium
Selenium Compounds
Sodium Selenite
61 Citations (Scopus)

Localization and Characterization of the 86- and 84-kDa Heat Shock Proteins in Hepa 1c1c7 Cells

Perdew, G. H., Hord, N., Hollenback, C. E. & Welsh, M. J., Jan 1 1993, In : Experimental Cell Research. 209, 2, p. 350-356 7 p.

Research output: Contribution to journalArticle

Heat-Shock Proteins
Antibodies
Cytosol
Cytoplasm
Anti-Idiotypic Antibodies
187 Citations (Scopus)

Loss of expression of transforming growth factor β in skin and skin tumors is associated with hyperproliferation and a high risk for malignant conversion

Glick, A. B., Kulkarni, A. B., Tennenbaum, T., Hennings, H., Flanders, K. C., O'Reilly, M., Sporn, M. B., Karlsson, S. & Yuspa, S. H., Jan 1 1993, In : Proceedings of the National Academy of Sciences of the United States of America. 90, 13, p. 6076-6080 5 p.

Research output: Contribution to journalArticle

Transforming Growth Factors
Skin
Papilloma
Neoplasms
Epidermis
7 Citations (Scopus)

Modulation of carcinogen-induced polyoma DNA replication by organoselenium and organosulfur chemopreventive agents

Foiles, P. G., Miglietta, L., Dolan, L. R., El-Bayoumy, K. & Ronai, Z., Jan 1 1993, In : International journal of oncology. 2, 3, p. 413-418 6 p.

Research output: Contribution to journalArticle

DNA Replication
Carcinogens
Chloramphenicol
Transferases
DNA Tumor Viruses
15 Citations (Scopus)

Monoclonal antibody neutralization of BPV-1

Christensen, N. & Kreider, J. W., Jan 1 1993, In : Virus Research. 28, 2, p. 195-202 8 p.

Research output: Contribution to journalArticle

Virion
Monoclonal Antibodies
Epitopes
Enzyme-Linked Immunosorbent Assay
Human papillomavirus 11
44 Citations (Scopus)

Opposite Stereoselective Resistance to Digestion by Phosphodiesterases I and II of Benzo[a]pyrene Diol Epoxide-Modified Oligonucleotide Adducts

Mao, B., Li, B., Cosman, M., Geacintov, N. E. & Amin, S., Jan 1 1993, In : Biochemistry. 32, 44, p. 11785-11793 9 p.

Research output: Contribution to journalArticle

spleen exonuclease
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide
Phosphodiesterase I
Benzo(a)pyrene
Epoxy Compounds
85 Citations (Scopus)

Phenobarbital induction and tissue-specific expression of the rat CYP2B2 gene in transgenic mice

Ramsden, R., Sommer, K. M. & Omiecinski, C. J., Jan 1 1993, In : Journal of Biological Chemistry. 268, 29, p. 21722-21726 5 p.

Research output: Contribution to journalArticle

Phenobarbital
Transgenic Mice
Rats
Genes
Tissue
26 Citations (Scopus)

Prolactin receptors are found on heterogeneous subpopulations of rat splenocytes

Viselli, S. M. & Mastro, A. M., Jan 1 1993, In : Endocrinology. 132, 2, p. 571-576 6 p.

Research output: Contribution to journalArticle

Prolactin Receptors
Lymphocytes
Immunocompetence
Differentiation Antigens
Surface Antigens
26 Citations (Scopus)

PyvS: A Dominantly Acting Gene in C3H/BiDa Mice Conferring Susceptibility to Tumor Induction by Polyoma Virus

Lukacher, A., Freund, R., Carroll, J. P., Bronson, R. T. & Benjamin, T. L., Sep 1 1993, In : Virology. 196, 1, p. 241-248 8 p.

Research output: Contribution to journalArticle

Polyomavirus
Inbred C3H Mouse
Genes
Virus Receptors
Dominant Genes
280 Citations (Scopus)

Raf exists in a native heterocomplex with hsp90 and p50 that can be reconstituted in a cell-free system

Stancato, L. F., Chow, Y. H., Hutchison, K. A., Perdew, G. H., Jove, R. & Pratt, W. B., Jan 1 1993, In : Journal of Biological Chemistry. 268, 29, p. 21711-21716 6 p.

Research output: Contribution to journalArticle

Oncogene Protein pp60(v-src)
Cell-Free System
Reticulocytes
Rabbits
Sf9 Cells
97 Citations (Scopus)

Regional distribution and expression modulation of cytochrome P-450 and epoxide hydrolase mRNAs in the rat brain

Schilter, B. & Omiecinski, C. J., 1993, In : Molecular Pharmacology. 44, 5, p. 990-996 7 p.

Research output: Contribution to journalArticle

Epoxide Hydrolases
Cytochrome P-450 Enzyme System
Cytochrome P-450 CYP1A2
Messenger RNA
Cytochrome P-450 CYP1A1
111 Citations (Scopus)

Regiospecific expression of cytochrome p-450s and microsomal epoxide hydrolase in human brain tissue

Farin, F. M. & Omiecinski, C. J., Jan 1 1993, In : Journal of Toxicology and Environmental Health. 40, 2-3, p. 317-335 19 p.

Research output: Contribution to journalArticle

Epoxide Hydrolases
Hydrolases
Cytochromes
Brain
Tissue
46 Citations (Scopus)

Roles of Human Hepatic and Pulmonary Cytochrome P450 Enzymes in the Metabolism of the Environmental Carcinogen 6-Nitrochrysene

Chae, Y. H., Yun, C. H., Guengerich, F. P., Kadlubar, F. F. & El-Bayoumy, K., Jan 1 1993, In : Cancer Research. 53, 9, p. 2028-2034 7 p.

Research output: Contribution to journalArticle

Environmental Carcinogens
Cytochrome P-450 Enzyme System
Lung
Liver
Microsomes
19 Citations (Scopus)

Skin test to assess immunity against cottontail rabbit papillomavirus antigens in rabbits with progressing papillomas or after papilloma regression

Höpfl, R. M., Christensen, N., Angell, M. G. & Kreider, J. W., Jan 1 1993, In : Journal of Investigative Dermatology. 101, 2, p. 227-231 5 p.

Research output: Contribution to journalArticle

Cottontail rabbit papillomavirus
Papilloma
Skin Tests
Immunity
Skin
87 Citations (Scopus)

Solution Conformation of the (+)-trans-anti-[BPh]dA Adduct opposite dT in a DNA Duplex: Intercalation of the Covalently Attached Benzo[c]phenanthrene to the 5′-Side of the Adduct Site without Disruption of the Modified Base Pair

Cosman, M., Fiala, R., Hingerty, B. E., Laryea, A., Lee, H., Harvey, R. G., Amin, S., Geacintov, N. E., Broyde, S. & Patel, D., Jan 1 1993, In : Biochemistry. 32, 46, p. 12488-12497 10 p.

Research output: Contribution to journalArticle

Intercalation
Base Pairing
Conformations
Protons
Polycyclic Aromatic Hydrocarbons
10 Citations (Scopus)
Nitrosamines
DNA Adducts
Aldehydes
Hemoglobins
Alcohols
4 Citations (Scopus)

Synthesis of N-(Purin-8-yl)arylamines

Swenson, D. H., El-Bayoumy, K., Shuie, G. H., Hecht, S. S., Fiala, E., Kadlubar, F. F. & Freeman, J. P., Jan 1 1993, In : Chemical Research in Toxicology. 6, 4, p. 480-485 6 p.

Research output: Contribution to journalArticle

Dimethylformamide
Thiourea
Derivatives
Carbodiimides
Methylation
11 Citations (Scopus)

The effect of the cytochrome P‐450 system inducers on the development of drosophila melanogaster

Fuchs, S. Y., Spiegelman, V. & Belitsky, G. A., Jan 1 1993, In : Journal of Biochemical Toxicology. 8, 2, p. 83-88 6 p.

Research output: Contribution to journalArticle

Drosophila melanogaster
Cytochrome P-450 Enzyme System
Larva
Ecdysone
Phenobarbital
8 Citations (Scopus)

The expression of forms of prolactin receptors in splenocytes and thymocytes of neonatal rats: the effect of milk ingestion.

Günes, H., Grove, D. S., Bour, B., Zawilla, S. & Mastro, A. M., Dec 1 1993, In : Endocrine Regulations. 27, 4, p. 193-200 8 p.

Research output: Contribution to journalArticle

Prolactin Receptors
Thymocytes
Prolactin
Milk
Eating
713 Citations (Scopus)

The molecular basis of the human serum paraoxonase activity polymorphism

Humbert, R., Adler, D. A., Disteche, C. M., Hassett, C., Omiecinski, C. J. & Furlong, C. E., Jan 1 1993, In : Nature Genetics. 3, 1, p. 73-76 4 p.

Research output: Contribution to journalArticle

Aryldialkylphosphatase
Paraoxon
Serum
Parathion
Restriction Mapping
115 Citations (Scopus)

The Suprabasal Expression of α6ß4 Integrin Is Associated with a High Risk for Malignant Progression in Mouse Skin Carcinogenesis

Tennenbaum, T., Weiner, A. K., Belanger, A. J., Glick, A. B., Hennings, H. & Yuspa, S. H., Oct 1993, In : Cancer Research. 53, 20, p. 4803-4810 8 p.

Research output: Contribution to journalArticle

Integrins
Carcinogenesis
Skin
Keratin-13
Neoplasms
28 Citations (Scopus)

Tumor-initiating activity on mouse skin of bay region diol-epoxides of 5,6-dimethylchrysene and benzo[c]phenanthrene

Amin, S., Desai, D. & Hecht, S. S., Oct 1 1993, In : Carcinogenesis. 14, 10, p. 2033-2037 5 p.

Research output: Contribution to journalArticle

Epoxy Compounds
Skin
Neoplasms
Hydrocarbons
Carcinogens
3 Citations (Scopus)

Unwinding and Hydrodynamic Flow Linear Dichroism Characteristics of Supercoiled DNA Covalently Modified with Two Isomeric Methylchrysene Diol Epoxides of Different Biological Activities

Balasta, L., Xu, R., Geacintov, N. E., Swenberg, C. E., Amin, S. & Hecht, S. S., Jan 1 1993, In : Chemical Research in Toxicology. 6, 5, p. 616-624 9 p.

Research output: Contribution to journalArticle

Superhelical DNA
Epoxy Compounds
Hydrodynamics
Bioactivity
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide
1994
10 Citations (Scopus)

Absence of enantioselectivity in the pharmacodynamics of P450 2B induction by 5‐ethyl‐5‐phenylhydantoin in the male rat liver or in cultured rat hepatocytes

Nims, R. W., Sidhu, J. S., Thomas, P. E., Mellini, D. W., Nelson, V. C., Omiecinski, C. J. & Lubet, R. A., Jan 1 1994, In : Journal of Biochemical Toxicology. 9, 6, p. 279-288 10 p.

Research output: Contribution to journalArticle

Pharmacodynamics
Enantioselectivity
Liver
Cytochrome P-450 Enzyme System
Rats
17 Citations (Scopus)

Activation of trans-l,2-dihydro-l,2-dihydroxy-6-aminochrysene to genotoxic metabolites by rat and human cytochromes P450

Yamazaki, H., Mimura, M., Oda, Y., Gonzalez, F. J., El-Bayoumy, K., Chae, Y. H., Guengerich, F. P. & Shimada, T., Mar 1 1994, In : Carcinogenesis. 15, 3, p. 465-470 6 p.

Research output: Contribution to journalArticle

Cytochrome P-450 Enzyme System
Liver Microsomes
6-chrysenamine
Acetyltransferases
Enzymes
95 Citations (Scopus)

Ah receptor in embryonic mouse palate and effects of TCDD on receptor expression

Abbott, B. D., Perdew, G. H. & Birnbaum, L. S., Jan 1 1994, In : Toxicology and Applied Pharmacology. 126, 1, p. 16-25 10 p.

Research output: Contribution to journalArticle

Aryl Hydrocarbon Receptors
Palate
Cleft Palate
Embryonic Structures
Halogenated Hydrocarbons
134 Citations (Scopus)

A mass spectrometric solution to the address problem of combinatorial libraries

Brummel, C. L., Lee, I. N. W., Zhou, Y., Benkovic, S. & Winograd, N., Jan 1 1994, In : Science. 264, 5157, p. 399-402 4 p.

Research output: Contribution to journalArticle

Secondary Ion Mass Spectrometry
Polystyrenes
Trifluoroacetic Acid
Peptides
Molecular Weight
206 Citations (Scopus)

An assembly domain of the Rous sarcoma virus Gag protein required late in budding

Wills, J., Cameron, C. E., Wilson, C. B., Xiang, Y., Bennett, R. P. & Leis, J., Oct 1994, In : Journal of Virology. 68, 10, p. 6605-6618 14 p.

Research output: Contribution to journalArticle

Rous sarcoma virus
gag Gene Products
Peptide Hydrolases
proteinases
mutants
143 Citations (Scopus)

Assembled baculovirus-expressed human papillomavirus type 11 L1 capsid protein virus-like particles are recognized by neutralizing monoclonal antibodies and induce high titres of neutralizing antibodies

Christensen, N. D., Hopfl, R., DiAngelo, S. L., Cladel, N. M., Patrick, S. D., Welsh, P. A., Budgeon, L. R., Reed, C. A. & Kreider, J. W., Jan 1 1994, In : Journal of General Virology. 75, 9, p. 2271-2276 6 p.

Research output: Contribution to journalArticle

Baculoviridae
Human papillomavirus 11
Capsid Proteins
Neutralizing Antibodies
Virion
22 Citations (Scopus)

Biochemical characterization of Epstein-Barr virus nuclear antigen 3A and 3C proteins

Sample, C. & Parker, B., Jan 1 1994, In : Virology. 205, 2, p. 534-539 6 p., 71675.

Research output: Contribution to journalArticle

Epstein-Barr Virus Nuclear Antigens
Human Herpesvirus 4
Recombinant Proteins
Proteins
DNA
5 Citations (Scopus)

Biomonitoring of nitropolynuclear aromatic hydrocarbons via protein and DNA adducts.

El-Bayoumy, K., Johnson, B. E., Roy, A. K., Upadhyaya, P. & Partian, S. J., Jan 1 1994, In : Research report (Health Effects Institute). 64

Research output: Contribution to journalArticle

1-nitropyrene
Aromatic Hydrocarbons
DNA Adducts
Environmental Monitoring
Hemoglobins
74 Citations (Scopus)

Catalytic antibody model and mutagenesis implicate arginine in transition-state stabilization

Roberts, V. A., Stewart, J., Benkovic, S. & Getzoff, E. D., Jan 20 1994, In : Journal of Molecular Biology. 235, 3, p. 1098-1116 19 p.

Research output: Contribution to journalArticle

Catalytic Antibodies
Mutagenesis
Arginine
Antigens
Catalysis
8 Citations (Scopus)

Characterization of resting and phorbol ester or concanavalin A activated bovine lymph node cells with leukocyte specific monoclonal antibodies

Hurley, D. J., Wilson, R. A., Baldwin, C. L., Liu, J. Y. & Mastro, A. M., Jan 1 1994, In : Veterinary Immunology and Immunopathology. 40, 1, p. 49-61 13 p.

Research output: Contribution to journalArticle

Phorbol Esters
concanavalin A
Concanavalin A
lymph nodes
leukocytes
113 Citations (Scopus)

Comparative effect of inorganic and organic selenocyanate derivatives in mammary cancer chemoprevention

Ip, C., El-Bayoumy, K., Upadhyaya, P., Ganther, H., Vadhanavikit, S. & Thompson, H., Feb 1 1994, In : Carcinogenesis. 15, 2, p. 187-192 6 p.

Research output: Contribution to journalArticle

Chemoprevention
Selenium
Selenium Compounds
Breast Neoplasms
Sodium Selenite
137 Citations (Scopus)

Comparison of the effects of an organic and an inorganic form of selenium on a mammary carcinoma cell line

Thompson, H. J., Wilson, A., Lu, J., Singh, M., Jiang, C., Upadhyaya, P., El-bayoumy, K. & Ip, C., Feb 1 1994, In : Carcinogenesis. 15, 2, p. 183-186 4 p.

Research output: Contribution to journalArticle

Selenious Acid
Selenium
Apoptosis
Breast Neoplasms
Cell Line
28 Citations (Scopus)

Contrasting incidence of ras mutations in rat mammary and mouse skin tumors induced by anti-benzo[c]phenanthrene-3,4-diol-1,2-epoxide

Ronai, Z. A., Gradia, S., El-bayoumy, K., Amin, S. & Hecht, S. S., Oct 1 1994, In : Carcinogenesis. 15, 10, p. 2113-2116 4 p.

Research output: Contribution to journalArticle

Epoxy Compounds
Breast
Skin
Mutation
Incidence
2 Citations (Scopus)

Convenient Synthesis of 3-Methoxybenz[a]anthracene-7,12-dione

Desai, D., Krzeminski, J. & Amin, S., Nov 1 1994, In : Chemical Research in Toxicology. 7, 6, p. 722-723 2 p.

Research output: Contribution to journalArticle

Epoxy Compounds
anthracene
ethylene
61 Citations (Scopus)

Developmental expression of human microsomal epoxide hydrolase

Omiecinski, C. J., Aicher, L. & Swenson, L., Jan 1 1994, In : Journal of Pharmacology and Experimental Therapeutics. 269, 1, p. 417-423 7 p.

Research output: Contribution to journalArticle

Epoxide Hydrolases
Fetus
Epoxy Compounds
RNA
Gestational Age
13 Citations (Scopus)

Development of methods to monitor exposure to 1-nitropyrene

El-Bayoumy, K., Johnson, B., Roy, A. K., Upadhyaya, P., Partian, S. & Hecht, S. S., Jan 1 1994, In : Environmental health perspectives. 102, SUPPL. 6, p. 31-37 7 p.

Research output: Contribution to journalArticle

1-nitropyrene
Hemoglobins
DNA Adducts
Heme
Radioactivity
36 Citations (Scopus)

Effect of tissue-culture substratum and extracellular matrix overlay on liver-selective and xenobiotic inducible gene expression in primary rat hepatocytes

Sidhu, J. S., Farin, F. M., Kavanagh, T. J. & Omiecinski, C. J., Dec 1 1994, In : In Vitro Toxicology: Journal of Molecular and Cellular Toxicology. 7, 3, p. 225-242 18 p.

Research output: Contribution to journalArticle

Tissue culture
Xenobiotics
Gene expression
Liver
Extracellular Matrix
10 Citations (Scopus)

Engineering proteases with altered specificity

Leis, J. P. & Cameron, C. E., Aug 1994, In : Current Opinion in Biotechnology. 5, 4, p. 403-408 6 p.

Research output: Contribution to journalArticle

Peptide Hydrolases
Substrate Specificity
Enzymes
Substrates
Viruses

Enzymatic preparation of [2,4,5,6,8-14C, 5′-3H]guanosine for use in biosynthetic studies of pterinoid and flavin compounds

Irby, R. & Adair, W. L., May 1 1994, In : Analytical Biochemistry. 218, 2, p. 413-416 4 p.

Research output: Contribution to journalArticle

Guanosine
Ribose
Guanine
Flavins
Pterins
27 Citations (Scopus)

Epstein-Barr virus types 1 and 2 have nearly identical LMP-1 transforming genes

Sample, J., Kieff, E. F. & Kieff, E. D., Jan 1 1994, In : Journal of General Virology. 75, 10, p. 2741-2746 6 p.

Research output: Contribution to journalArticle

Human Herpesvirus 4
Oncogenes
Genes
Nuclear Proteins
Lymphocytes
73 Citations (Scopus)

Expression of cytochrome P450s and microsomal epoxide hydrolase in primary cultures of human umbilical vein endothelial cells

Farin, F. M., Pohlman, T. H. & Omiecinski, C. J., Jan 1 1994, In : Toxicology and Applied Pharmacology. 124, 1, p. 1-9 9 p.

Research output: Contribution to journalArticle

Epoxide Hydrolases
Endothelial cells
Human Umbilical Vein Endothelial Cells
Cytochromes
Cell culture
52 Citations (Scopus)
Adenosylmethionine Decarboxylase
Putrescine
Escherichia coli
Chemical activation
Mutation
48 Citations (Scopus)

Fidelity of in Vitro DNA Strand Transfer Reactions Catalyzed by HIV-1 Reverse Transcriptase

Peliska, J. A. & Benkovic, S., Apr 1 1994, In : Biochemistry. 33, 13, p. 3890-3895 6 p.

Research output: Contribution to journalArticle

Genetic Recombination
Nucleotides
DNA
DNA Sequence Analysis
Mutagenesis
13 Citations (Scopus)

Formation of the Acrolein-Derived 1,N2-Propanodeoxyguanosine Adducts in DNA upon Reaction with 3-(N-Carbethoxy-N-nitrosamino)propionaldehyde

Chung, F. L., Krzeminski, J., Wang, M., Chen, H. J. C. & Prokopczyk, B., Jan 1 1994, In : Chemical research in toxicology. 7, 1, p. 62-67 6 p.

Research output: Contribution to journalArticle

Acrolein
Carbamates
DNA Adducts
DNA
Arecoline
65 Citations (Scopus)

Hematopoietic placental protein 14: An immunosuppressive factor in cells of the megakaryocytic lineage

Morrow, D. M., Xiong, N., Getty, R. R., Ratajczak, M. Z., Morgan, D., Seppala, M., Riittinen, L., Gewirtz, A. M. & Tykocinski, M. L., Dec 1 1994, In : American Journal of Pathology. 145, 6, p. 1485-1495 11 p.

Research output: Contribution to journalArticle

Pregnancy Proteins
Cell Lineage
Immunosuppressive Agents
Messenger RNA
K562 Cells
444 Citations (Scopus)

Human microsomal epoxide hydrolase: Genetic poloymorphism and functional expression in vitro of amino acid variants

Hassett, C., Alcher, L., Sidhu, J. S. & Omieclnskl, C. J., Mar 1 1994, In : Human Molecular Genetics. 3, 3, p. 421-428 8 p.

Research output: Contribution to journalArticle

Epoxide Hydrolases
Amino Acids
Exons
Proteins
Alleles