Research Output 1963 2020

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2018
3 Citations (Scopus)

Muscle contractures in patients with cerebral palsy and acquired brain injury are associated with extracellular matrix expansion, pro-inflammatory gene expression, and reduced rRNA synthesis

Von Walden, F., Gantelius, S., Liu, C., Borgström, H., Björk, L., Gremark, O., Stål, P., Nader, G. A. & PontéN, E., Aug 1 2018, In : Muscle and Nerve. 58, 2, p. 277-285 9 p.

Research output: Contribution to journalArticle

Contracture
Cerebral Palsy
Brain Injuries
Extracellular Matrix
Gene Expression
2 Citations (Scopus)

Myeloperoxidase deficiency attenuates systemic and dietary iron-induced adverse effects

Xiao, X., Saha, P., Yeoh, B. S., Hipp, J. A., Singh, V. & Vijay-Kumar, M., Dec 2018, In : Journal of Nutritional Biochemistry. 62, p. 28-34 7 p.

Research output: Contribution to journalArticle

Dietary Iron
Peroxidase
Iron
Toxicity
Leukocyte Elastase
16 Citations (Scopus)

Nanoliposome C6-Ceramide Increases the Anti-tumor Immune Response and Slows Growth of Liver Tumors in Mice

Li, G., Liu, D., Kimchi, E. T., Kaifi, J. T., Qi, X., Manjunath, Y., Liu, X., Deering, T., Avella, D. M., Fox, T., Rockey, D. C., Schell, T. D., Kester, M. & Staveley-O'Carroll, K. F., Mar 2018, In : Gastroenterology. 154, 4, p. 1024-1036.e9

Research output: Contribution to journalArticle

Liver
Growth
Neoplasms
Macrophages
Neoplasm Antigens
3 Citations (Scopus)

Neuroprotective role of the ron receptor tyrosine kinase underlying central nervous system inflammation in health and disease

Dey, A., Allen, J. N., Fraser, J. W., Snyder, L. M., Tian, Y., Zhang, L., Paulson, R. F., Patterson, A., Cantorna, M. T. & Hankey-Giblin, P. A., Mar 19 2018, In : Frontiers in immunology. 9, MAR, 513.

Research output: Contribution to journalArticle

Receptor Protein-Tyrosine Kinases
Central Nervous System
Inflammation
Health
Nerve Tissue
15 Citations (Scopus)

Neutrophil peptidyl arginine deiminase-4 has a pivotal role in ischemia/reperfusion-induced acute kidney injury

Raup-Konsavage, W. M., Wang, Y., Wang, W. W., Feliers, D., Ruan, H. & Reeves, W. B., Feb 1 2018, In : Kidney International. 93, 2, p. 365-374 10 p.

Research output: Contribution to journalArticle

Acute Kidney Injury
Reperfusion
Neutrophils
Ischemia
Kidney
4 Citations (Scopus)

NFkB hyperactivation causes invasion of esophageal squamous cell carcinoma with EGFR overexpression and p120-catenin down-regulation

Lehman, H. L., Kidacki, M., Warrick, J. I. & Stairs, D. B., Jan 1 2018, In : Oncotarget. 9, 13, p. 11180-11196 17 p.

Research output: Contribution to journalArticle

Down-Regulation
rho-Associated Kinases
Esophageal Squamous Cell Carcinoma
delta catenin
Keratinocytes
2 Citations (Scopus)

Nonenvelopment role for the ESCRTIII complex during human cytomegalovirus infection

Streck, N. T., Carmichael, J. & Buchkovich, N. J., Jun 1 2018, In : Journal of virology. 92, 12, e02096-17.

Research output: Contribution to journalArticle

Endosomal Sorting Complexes Required for Transport
Human herpesvirus 5
Cytomegalovirus Infections
sorting
Cytomegalovirus
3 Citations (Scopus)

Nuclear, cytosolic, and surface-localized poly(A)-binding proteins of Plasmodium yoelii

Minns, A. M., Hart, K. J., Subramanian, S., Hafenstein, S. & Lindner, S. E., Jan 1 2018, In : mSphere. 3, 1, e00435-17.

Research output: Contribution to journalArticle

Poly(A)-Binding Proteins
Plasmodium yoelii
Plasmodium
Sporozoites
Parasites
6 Citations (Scopus)

Old receptor, new tricks—The ever-expanding universe of aryl hydrocarbon receptor functions. Report from the 4th AHR meeting, 29–31 August 2018 in Paris, France

Esser, C., Lawrence, B. P., Sherr, D. H., Perdew, G. H., Puga, A., Barouki, R. & Coumoul, X., Nov 15 2018, In : International journal of molecular sciences. 19, 11, 3603.

Research output: Contribution to journalArticle

Aryl Hydrocarbon Receptors
Paris
France
universe
hydrocarbons
6 Citations (Scopus)

Oncogenic KRAS suppresses store-operated Ca2+ entry and ICRAC through ERK pathway-dependent remodelling of STIM expression in colorectal cancer cell lines

Pierro, C., Zhang, X., Kankeu, C., Trebak, M., Bootman, M. D. & Roderick, H. L., Jun 2018, In : Cell Calcium. 72, p. 70-80 11 p.

Research output: Contribution to journalArticle

MAP Kinase Signaling System
Colorectal Neoplasms
Cell Line
Cell Movement
Alleles
5 Citations (Scopus)

Oral supplementation with liposomal glutathione elevates body stores of glutathione and markers of immune function

Sinha, R., Sinha, I., Calcagnotto, A., Trushin, N., Haley, J. S., Schell, T. & Richie, J., Jan 1 2018, In : European Journal of Clinical Nutrition. 72, 1, p. 105-111 7 p.

Research output: Contribution to journalArticle

Glutathione
Oxidative Stress
Biomarkers
8-epi-prostaglandin F2alpha
Blood Cells
4 Citations (Scopus)

Peroxisomes support human herpesvirus 8 latency by stabilizing the viral oncogenic protein vFLIP via the MAVS-TRAF complex

Choi, Y. B., Choi, Y. & Harhaj, E. W., May 2018, In : PLoS pathogens. 14, 5, e1007058.

Research output: Contribution to journalArticle

CASP8 and FADD-Like Apoptosis Regulating Protein
Human Herpesvirus 8
Peroxisomes
Viral Proteins
Antiviral Agents
5 Citations (Scopus)
Androgen Receptors
Reactive Oxygen Species
Prostatic Neoplasms
Apoptosis
Prostate-Specific Antigen
13 Citations (Scopus)

PheWAS and Beyond: The Landscape of Associations with Medical Diagnoses and Clinical Measures across 38,662 Individuals from Geisinger

Verma, A., Lucas, A., Verma, S. S., Zhang, Y., Josyula, N., Khan, A., Hartzel, D. N., Lavage, D. R., Leader, J., Ritchie, M. D. & Pendergrass, S. A., Apr 5 2018, In : American Journal of Human Genetics. 102, 4, p. 592-608 17 p.

Research output: Contribution to journalArticle

Single Nucleotide Polymorphism
Phenotype
Electronic Health Records
Nucleic Acid Regulatory Sequences
Genome-Wide Association Study
2 Citations (Scopus)

Pore properties of Orai1 calcium channel dimers and their activation by the STIM1 ER calcium sensor

Cai, X., Nwokonko, R. M., Loktionova, N. A., Abdulqadir, R., Baraniak, J. H., Wang, Y., Trebak, M., Zhou, Y. & Gill, D. L., Jan 1 2018, In : Journal of Biological Chemistry. 293, 33, p. 12962-12974 13 p.

Research output: Contribution to journalArticle

Calcium Channels
Linings
Endoplasmic Reticulum
Dimers
Chemical activation
3 Citations (Scopus)

Prebiotic effects of white button mushroom (Agaricus bisporus) feeding on succinate and intestinal gluconeogenesis in C57BL/6 mice

Tian, Y., Nichols, R. G., Roy, P., Gui, W., Smith, P. B., Zhang, J., Lin, Y., Weaver, V., Cai, J., Patterson, A. D. & Cantorna, M. T-A., Jun 1 2018, In : Journal of Functional Foods. 45, p. 223-232 10 p.

Research output: Contribution to journalArticle

Agaricus
Prebiotics
Agaricus bisporus
Gluconeogenesis
gluconeogenesis
1 Citation (Scopus)

Preoperative urine culture is unnecessary in asymptomatic men prior to prostate needle biopsy

Qi, D. Z., Lehman, K., Dewan, K., Kirimanjeswara, G. S. & Raman, J., Jan 1 2018, In : International Urology and Nephrology. 50, 1, p. 21-24 4 p.

Research output: Contribution to journalArticle

Needle Biopsy
Prostate
Urine
Biopsy
Bacteriuria
6 Citations (Scopus)

Probing the Internal Microstructure of Polyamide Thin-Film Composite Membranes Using Resonant Soft X-ray Scattering

Culp, T. E., Ye, D., Paul, M., Roy, A., Behr, M. J., Jons, S., Rosenberg, S., Wang, C., Gomez, E. W., Kumar, M. & Gomez, E. D., Aug 21 2018, In : ACS Macro Letters. 7, 8, p. 927-932 6 p.

Research output: Contribution to journalArticle

Composite membranes
Nylons
X ray scattering
Polyamides
Thin films

Production and characterization of a novel HPV anti-L2 monoclonal antibody panel

Bywaters, S. M., Brendle, S. A., Biryukov, J., Wang, J. W., Walston, J., Milici, J., Roden, R. B., Meyers, C. & Christensen, N. D., Nov 2018, In : Virology. 524, p. 106-113 8 p.

Research output: Contribution to journalArticle

Epitopes
Monoclonal Antibodies
Capsid Proteins
Capsid
Research Personnel
14 Citations (Scopus)

Raman Spectroscopy, Photocatalytic Degradation, and Stabilization of Atomically Thin Chromium Tri-iodide

Shcherbakov, D., Stepanov, P., Weber, D., Wang, Y., Hu, J., Zhu, Y., Watanabe, K., Taniguchi, T., Mao, Z., Windl, W., Goldberger, J., Bockrath, M. & Lau, C. N., 2018, In : Nano letters. 18, 7, p. 4214-4219 6 p.

Research output: Contribution to journalArticle

Iodides
Chromium
iodides
Raman spectroscopy
chromium
1 Citation (Scopus)

Region 3.2 of the factor controls the stability of rRNA promoter complexes and potentiates their repression by DksA

Pupov, D., Petushkov, I., Esyunina, D., Murakami, K. S. & Kulbachinskiy, A., Jan 1 2018, In : Nucleic acids research. 46, 21, p. 11477-11487 11 p.

Research output: Contribution to journalArticle

Genetic Promoter Regions
Fingers
DNA-Directed RNA Polymerases
GTP Pyrophosphokinase
Bacterial RNA
3 Citations (Scopus)
Calcitriol Receptors
Microbiota
Metabolism
Vitamin D
Anti-Bacterial Agents
2 Citations (Scopus)

Resonant Soft X-Ray Scattering Provides Protein Structure with Chemical Specificity

Ye, D., Le, T. P., Kuei, B., Zhu, C., Zwart, P. H., Wang, C., Gomez, E. D. & Gomez, E. W., Nov 6 2018, In : Structure. 26, 11, p. 1513-1521.e3

Research output: Contribution to journalArticle

X-Rays
Proteins
Carbon
Amino Acid Motifs
Bovine Serum Albumin
5 Citations (Scopus)

Resonant soft X-ray scattering reveals cellulose microfibril spacing in plant primary cell walls

Ye, D., Kiemle, S. N., Rongpipi, S., Wang, X., Wang, C., Cosgrove, D. J., Gomez, E. W. & Gomez, E. D., Dec 1 2018, In : Scientific reports. 8, 1, 12449.

Research output: Contribution to journalArticle

Microfibrils
Plant Cells
Cellulose
Cell Wall
X-Rays
2 Citations (Scopus)

RET fusions observed in lung and colorectal cancers are sensitive to ponatinib

Gozgit, J. M., Chen, T. H., Song, Y., Wardwell, S., Wang, F., Cai, J., Li, H., Edgren, H., Rivera, V. M. & Pritchard, J., Jul 1 2018, In : Oncotarget. 9, 51, p. 29654-29664 11 p.

Research output: Contribution to journalArticle

Transfection
Colorectal Neoplasms
Lung Neoplasms
Heterografts
Genomics
4 Citations (Scopus)

Revisiting the physiological effects of methylene blue as a treatment of cyanide intoxication

Haouzi, P., Gueguinou, M., Sonobe, T., Haouzi, A., Tubbs, N., Trebak, M., Cheung, J. & Bouillaud, F., Sep 2 2018, In : Clinical Toxicology. 56, 9, p. 828-840 13 p.

Research output: Contribution to journalArticle

Methylene Blue
Cyanides
Rats
Adenosine Diphosphate
Animals
4 Citations (Scopus)

Role of HSP90 in the Regulation of de Novo Purine Biosynthesis

Pedley, A. M., Karras, G. I., Zhang, X., Lindquist, S. & Benkovic, S., Jun 12 2018, In : Biochemistry. 57, 23, p. 3217-3221 5 p.

Research output: Contribution to journalArticle

Biosynthesis
Molecular Chaperones
Biosynthetic Pathways
Enzymes
Purines

Ron Receptor Signaling Ameliorates Hepatic Fibrosis in a Diet-Induced Nonalcoholic Steatohepatitis Mouse Model

Allen, J., Zhang, J., Quickel, M. D., Kennett, M. J., Patterson, A. D. & Giblin, P. H., Sep 7 2018, In : Journal of Proteome Research. 17, 9, p. 3268-3280 13 p.

Research output: Contribution to journalArticle

Nutrition
Liver
Fibrosis
Collagen
Diet
9 Citations (Scopus)

Salt-Responsive Metabolite, β-Hydroxybutyrate, Attenuates Hypertension

Chakraborty, S., Galla, S., Cheng, X., Yeo, J. Y., Mell, B., Singh, V., Yeoh, B. S., Saha, P., Mathew, A. V., Vijay-Kumar, M. & Joe, B., Oct 16 2018, In : Cell Reports. 25, 3, p. 677-689.e4

Research output: Contribution to journalArticle

Hydroxybutyrates
Metabolites
Salts
Hypertension
Ketone Bodies
2 Citations (Scopus)

Searching for topological Fermi arcs via quasiparticle interference on a type-II Weyl semimetal MoTe 2

Iaia, D., Chang, G., Chang, T-R., Hu, J., Mao, Z., Lin, H., Yan, S. & Madhavan, V., 2018, In : npj Quantum Materials. 3, 1

Research output: Contribution to journalArticle

Metalloids
metalloids
Fermi level
arcs
Scattering
9 Citations (Scopus)

Selenoproteins regulate stress erythroid progenitors and spleen microenvironment during stress erythropoiesis

Liao, C., Hardison, R. C., Kennett, M. J., Carlson, B. A., Paulson, R. & Prabhu, K. S., Jun 7 2018, In : Blood. 131, 23, p. 2568-2580 13 p.

Research output: Contribution to journalArticle

Selenoproteins
Erythroblasts
Erythropoiesis
Selenium
Spleen

Simple Polymethylglutarimide Microfluidic Channels With Hydrogel-Assisted Fluid Exchange

Gupta, A. V., Brigeman, A. N., Gomez, E. W. & Jackson, T. N., Apr 1 2018, In : IEEE Transactions on Nanobioscience. 17, 2, p. 97-101 5 p.

Research output: Contribution to journalArticle

Microfluidics
Hydrogel
Lipid Bilayers
Hydrogels
Fluorescence
4 Citations (Scopus)

Simplified ChIP-exo assays

Rossi, M. J., Lai, W. K. M. & Pugh, B. F., Dec 1 2018, In : Nature communications. 9, 1, 2842.

Research output: Contribution to journalArticle

Libraries
Noise
Assays
genome
Genome
3 Citations (Scopus)

Single-molecule sequencing reveals patterns of preexisting drug resistance that suggest treatment strategies in Philadelphia-positive leukemias

Schmitt, M. W., Pritchard, J. R., Leighow, S. M., Aminov, B. I., Beppu, L., Kim, D. S., Hodgson, J. G., Rivera, V. M., Loeb, L. A. & Radich, J. P., Nov 1 2018, In : Clinical Cancer Research. 24, 21, p. 5321-5334 14 p.

Research output: Contribution to journalArticle

Drug Resistance
Leukemia
Mutation
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Pharmaceutical Preparations
1 Citation (Scopus)

Standardized fraction of Xylocarpus moluccensis fruits improve vascular relaxation and plaque stability in dyslipidemic models of atherosclerosis

Kanshana, J. S., Rebello, S. C., Pathak, P., Kanuri, B. N., Aggarwal, H., Srivastava, V., Khanna, V., Singh, V., Jagavelu, K., Barthwal, M. K. & Dikshit, M., Mar 1 2018, In : Journal of Ethnopharmacology. 213, p. 81-91 11 p.

Research output: Contribution to journalArticle

Apolipoproteins E
Blood Vessels
Fruit
Atherosclerosis
High Fat Diet

Structural and Functional Analysis of the Gut Microbiome for Toxicologists

Nichols, R. G., Cai, J., Murray, I. A., Koo, I., Smith, P. B., Perdew, G. H. & Patterson, A. D., Nov 1 2018, In : Current Protocols in Toxicology. 78, 1, e54.

Research output: Contribution to journalArticle

Functional analysis
Structural analysis
Metabolomics
Poisons
Metabolites
1 Citation (Scopus)

Structural Origins of FRET-Observed Nascent Chain Compaction on the Ribosome

Nissley, D. A. & O'Brien, Jr., E. P., Nov 1 2018, In : Journal of Physical Chemistry B. 122, 43, p. 9927-9937 11 p.

Research output: Contribution to journalArticle

ribosomes
Compaction
Fluorescence
folding
Proteins
4 Citations (Scopus)

Structure-function comparisons of (p)ppApp vs (p)ppGpp for Escherichia coli RNA polymerase binding sites and for rrnB P1 promoter regulatory responses in vitro

Bruhn-Olszewska, B., Molodtsov, V., Sobala, M., Dylewski, M., Murakami, K., Cashel, M. & Potrykus, K., Aug 1 2018, In : Biochimica et Biophysica Acta - Gene Regulatory Mechanisms. 1861, 8, p. 731-742 12 p.

Research output: Contribution to journalArticle

DNA-Directed RNA Polymerases
Escherichia coli
Binding Sites
Transcription
Guanosine
32 Citations (Scopus)

Substrate-driven chemotactic assembly in an enzyme cascade

Zhao, X., Palacci, H., Yadav, V., Spiering, M. M., Gilson, M. K., Butler, P. J., Hess, H., Benkovic, S. J. & Sen, A., Mar 1 2018, In : Nature Chemistry. 10, 3, p. 311-317 7 p.

Research output: Contribution to journalArticle

Enzymes
Substrates
Glucose-6-Phosphate Isomerase
Phosphofructokinases
Fructose-Bisphosphate Aldolase
6 Citations (Scopus)

Superinfection exclusion between two highrisk human papillomavirus types during a coinfection

Biryukov, J. & Meyers, C., Apr 1 2018, In : Journal of virology. 92, 8, e01993-17.

Research output: Contribution to journalArticle

Superinfection
Papillomaviridae
Coinfection
mixed infection
Life Cycle Stages
1 Citation (Scopus)

Synthetic cannabinoid activity against colorectal cancer cells

Raup-Konsavage, W. M., Johnson, M., Legare, C. A., Yochum, G. S., Morgan, D. J. & Vrana, K. E., Mar 2018, In : Cannabis and Cannabinoid Research. 3, 1, p. 272-281 10 p.

Research output: Contribution to journalArticle

Open Access
Cannabinoids
Colorectal Neoplasms
Cell Survival
Cell Line
Libraries
7 Citations (Scopus)

Targeting insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) in metastatic melanoma to increase efficacy of BRAF V600E inhibitors

Kim, T. W., Havighurst, T., Kim, K. M., Albertini, M., Xu, Y. G. & Spiegelman, V., May 1 2018, In : Molecular Carcinogenesis. 57, 5, p. 678-683 6 p.

Research output: Contribution to journalArticle

Insulin-Like Growth Factor Binding Protein 2
Melanoma
Messenger RNA
Mitogen-Activated Protein Kinase Kinases
Skin Neoplasms
8 Citations (Scopus)

T-cell Immunoglobulin and ITIM Domain Contributes to CD8 + T-cell Immunosenescence

Song, Y., Wang, B., Song, R., Hao, Y., Wang, D., Li, Y., Jiang, Y., Xu, L., Ma, Y., Zheng, H., Kong, Y. & Zeng, H., Apr 2018, In : Aging cell. 17, 2, e12716.

Research output: Contribution to journalArticle

Tyrosine
Immunoglobulins
T-Lymphocytes
Programmed Cell Death 1 Receptor
Down-Regulation
4 Citations (Scopus)

Temperature- and field-driven spin reorientations in triple-layer ruthenate Sr4Ru3O10

Zhu, M., Li, P. G., Wang, Y., Cao, H. B., Tian, W., Zhang, H. D., Phelan, B. D., Mao, Z. Q. & Ke, X., 2018, In : Scientific reports. 8, 1

Research output: Contribution to journalArticle

retraining
temperature
magnetic fields
neutron diffraction
degrees of freedom
1 Citation (Scopus)

TGFβ1-induced expression of caldesmon mediates epithelial–mesenchymal transition

Nalluri, S. M., O'Connor, J. W., Virgi, G. A., Stewart, S. E., Ye, D. & Gomez, E. W., May 1 2018, In : Cytoskeleton. 75, 5, p. 201-212 12 p.

Research output: Contribution to journalArticle

Calmodulin-Binding Proteins
Actins
Focal Adhesions
Cytoskeletal Proteins
Myofibroblasts
2 Citations (Scopus)
lactation stage
Micelles
micelles
skim milk
Caseins
3 Citations (Scopus)

The fucose salvage pathway inhibits invadopodia formation and extracellular matrix degradation in melanoma cells

Keeley, T., Lin, S., Lester, D. K., Lau, E. K. & Yang, S., Jun 2018, In : PloS one. 13, 6, e0199128.

Research output: Contribution to journalArticle

Salvaging
Fucose
fucose
melanoma
extracellular matrix
16 Citations (Scopus)

The gut microbiota regulates endocrine vitamin D metabolism through fibroblast growth factor 23

Bora, S. A., Kennett, M. J., Smith, P. B., Patterson, A. D. & Cantorna, M. T., Mar 2 2018, In : Frontiers in immunology. 9, MAR, 408.

Research output: Contribution to journalArticle

Dihydroxycholecalciferols
Vitamin D
Microbiota
Citrobacter rodentium
Homeostasis
3 Citations (Scopus)

The hepatitis C viral nonstructural protein 5A stabilizes growth-regulatory human transcripts

Guo, L., Sharma, S. D., Debes, J., Beisang, D., Rattenbacher, B., Louis, I. V. S., Wiesner, D. L., Cameron, C. E. & Bohjanen, P. R., Jan 1 2018, In : Nucleic acids research. 46, 5, p. 2537-2547 11 p.

Research output: Contribution to journalArticle

Viral Nonstructural Proteins
Hepatitis C
Growth
Hepacivirus
Messenger RNA
7 Citations (Scopus)

The HSV-1 mechanisms of cell-to-cell spread and fusion are critically dependent on host PTP1B

Carmichael, J. C., Yokota, H., Craven, R. C., Schmitt, A. & Wills, J. W., May 2018, In : PLoS pathogens. 14, 5, e1007054.

Research output: Contribution to journalArticle

Cell Fusion
Human Herpesvirus 1
Giant Cells
Neutralizing Antibodies
Pharmaceutical Preparations