Research Output 1963 2019

4 Citations (Scopus)

Structure-function comparisons of (p)ppApp vs (p)ppGpp for Escherichia coli RNA polymerase binding sites and for rrnB P1 promoter regulatory responses in vitro

Bruhn-Olszewska, B., Molodtsov, V., Sobala, M., Dylewski, M., Murakami, K., Cashel, M. & Potrykus, K., Aug 1 2018, In : Biochimica et Biophysica Acta - Gene Regulatory Mechanisms. 1861, 8, p. 731-742 12 p.

Research output: Contribution to journalArticle

DNA-Directed RNA Polymerases
Escherichia coli
Binding Sites
28 Citations (Scopus)

Substrate-driven chemotactic assembly in an enzyme cascade

Zhao, X., Palacci, H., Yadav, V., Spiering, M. M., Gilson, M. K., Butler, P. J., Hess, H., Benkovic, S. & Sen, A., Mar 1 2018, In : Nature Chemistry. 10, 3, p. 311-317 7 p.

Research output: Contribution to journalArticle

Glucose-6-Phosphate Isomerase
Fructose-Bisphosphate Aldolase
5 Citations (Scopus)

Superinfection exclusion between two highrisk human papillomavirus types during a coinfection

Biryukov, J. & Meyers, C., Apr 1 2018, In : Journal of virology. 92, 8, e01993-17.

Research output: Contribution to journalArticle

mixed infection
Life Cycle Stages
1 Citation (Scopus)

Synthetic cannabinoid activity against colorectal cancer cells

Raup-Konsavage, W. M., Johnson, M., Legare, C. A., Yochum, G., Morgan, D. & Vrana, K., Mar 1 2018, In : Cannabis and Cannabinoid Research. 3, 1, p. 272-281 10 p.

Research output: Contribution to journalArticle

Open Access
Colorectal Neoplasms
Cell Survival
Cell Line
7 Citations (Scopus)

Targeting insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) in metastatic melanoma to increase efficacy of BRAF V600E inhibitors

Kim, T. W., Havighurst, T., Kim, K. M., Albertini, M., Xu, Y. G. & Spiegelman, V., May 1 2018, In : Molecular Carcinogenesis. 57, 5, p. 678-683 6 p.

Research output: Contribution to journalArticle

Insulin-Like Growth Factor Binding Protein 2
Messenger RNA
Mitogen-Activated Protein Kinase Kinases
Skin Neoplasms
5 Citations (Scopus)

T-cell Immunoglobulin and ITIM Domain Contributes to CD8 + T-cell Immunosenescence

Song, Y., Wang, B., Song, R., Hao, Y., Wang, D., Li, Y., Jiang, Y., Xu, L., Ma, Y., Zheng, H., Kong, Y. & Zeng, H., Apr 1 2018, In : Aging cell. 17, 2, e12716.

Research output: Contribution to journalArticle

Programmed Cell Death 1 Receptor
4 Citations (Scopus)

Temperature- and field-driven spin reorientations in triple-layer ruthenate Sr4Ru3O10

Zhu, M., Li, P. G., Wang, Y., Cao, H. B., Tian, W., Zhang, H. D., Phelan, B. D., Mao, Z. Q. & Ke, X., 2018, In : Scientific reports. 8, 1

Research output: Contribution to journalArticle

magnetic fields
neutron diffraction
degrees of freedom

TGFβ1-induced expression of caldesmon mediates epithelial–mesenchymal transition

Nalluri, S. M., O'Connor, J. W., Virgi, G. A., Stewart, S. E., Ye, D. & Gomez, E. W., May 1 2018, In : Cytoskeleton. 75, 5, p. 201-212 12 p.

Research output: Contribution to journalArticle

Calmodulin-Binding Proteins
Focal Adhesions
Cytoskeletal Proteins
1 Citation (Scopus)
lactation stage
skim milk
3 Citations (Scopus)

The fucose salvage pathway inhibits invadopodia formation and extracellular matrix degradation in melanoma cells

Keeley, T., Lin, S., Lester, D. K., Lau, E. K. & Yang, S., Jun 1 2018, In : PloS one. 13, 6, e0199128.

Research output: Contribution to journalArticle

extracellular matrix
13 Citations (Scopus)

The gut microbiota regulates endocrine vitamin D metabolism through fibroblast growth factor 23

Bora, S. A., Kennett, M. J., Smith, P. B., Patterson, A. D. & Cantorna, M. T-A., Mar 2 2018, In : Frontiers in immunology. 9, MAR, 408.

Research output: Contribution to journalArticle

Vitamin D
Citrobacter rodentium
3 Citations (Scopus)

The hepatitis C viral nonstructural protein 5A stabilizes growth-regulatory human transcripts

Guo, L., Sharma, S. D., Debes, J., Beisang, D., Rattenbacher, B., Louis, I. V. S., Wiesner, D. L., Cameron, C. E. & Bohjanen, P. R., Jan 1 2018, In : Nucleic acids research. 46, 5, p. 2537-2547 11 p.

Research output: Contribution to journalArticle

Viral Nonstructural Proteins
Hepatitis C
Messenger RNA
6 Citations (Scopus)

The HSV-1 mechanisms of cell-to-cell spread and fusion are critically dependent on host PTP1B

Carmichael, J. C., Yokota, H., Craven, R., Schmitt, A. P. & Wills, J., May 1 2018, In : PLoS pathogens. 14, 5, e1007054.

Research output: Contribution to journalArticle

Cell Fusion
Human Herpesvirus 1
Giant Cells
Neutralizing Antibodies
Pharmaceutical Preparations
6 Citations (Scopus)

The human ion channel TRPM2 modulates neuroblastoma cell survival and mitochondrial function through Pyk2, CREB, and MCU activation

Hirschler-Laszkiewicz, I., Chen, S., Bao, L., Wang, J., Zhang, X. Q., Santhanam, S., Keefer, K., Madesh, M., Cheung, J. Y. & Miller, B., Oct 6 2018, In : American Journal of Physiology - Cell Physiology. 315, 4, p. C571-C586

Research output: Contribution to journalArticle

Focal Adhesion Kinase 2
Transient Receptor Potential Channels
Ion Channels
Cell Survival
12 Citations (Scopus)

The human papillomavirus E6 oncoprotein targets USP15 and TRIM25 to suppress RIG-I-mediated innate immune signaling

Chiang, C., Pauli, E. K., Biryukov, J., Feister, K. F., Meng, M., White, E. A., Münger, K., Howley, P. M., Meyers, C. & Gack, M. U., Mar 1 2018, In : Journal of virology. 92, 6, e01737-17.

Research output: Contribution to journalArticle

retinoic acid
Oncogene Proteins
2 Citations (Scopus)

The SAGA/TREX-2 subunit Sus1 binds widely to transcribed genes and affects mRNA turnover globally

García-Molinero, V., García-Martínez, J., Reja, R., Furió-Tarí, P., Antúnez, O., Vinayachandran, V., Conesa, A., Pugh, B. F., Pérez-Ortín, J. E. & Rodríguez-Navarro, S., Mar 29 2018, In : Epigenetics and Chromatin. 11, 1, 13.

Research output: Contribution to journalArticle

Transcription Factor TFIID
Messenger RNA
16 Citations (Scopus)

The store-operated calcium channels in cancer metastasis: from cell migration, invasion to metastatic colonization

Mo, P. & Yang, S., Jan 1 2018, In : Frontiers in Bioscience - Landmark. 23, 7, p. 1241-1256 16 p.

Research output: Contribution to journalArticle

Calcium Channels
Cell Movement
Neoplasm Metastasis
11 Citations (Scopus)

The wide utility of rabbits as models of human diseases

Esteves, P. J., Abrantes, J., Baldauf, H. M., BenMohamed, L., Chen, Y., Christensen, N., González-Gallego, J., Giacani, L., Hu, J., Kaplan, G., Keppler, O. T., Knight, K. L., Kong, X. P., Lanning, D. K., Le Pendu, J., De Matos, A. L., Liu, J., Liu, S., Lopes, A. M., Lu, S. & 17 others, Lukehart, S., Manabe, Y. C., Neves, F., McFadden, G., Pan, R., Peng, X., de Sousa-Pereira, P., Pinheiro, A., Rahman, M., Ruvoën-Clouet, N., Subbian, S., Tuñón, M. J., van der Loo, W., Vaine, M., Via, L. E., Wang, S. & Mage, R., May 1 2018, In : Experimental and Molecular Medicine. 50, 5, 66.

Research output: Contribution to journalArticle

Virus Diseases
Acquired Immunodeficiency Syndrome
Rabies Vaccines

Thickness evolution of transport properties in exfoliated Fe1+yTe nanoflakes

Hsieh, T-W., Zou, T., Hu, J., Mao, Z. Q., Zhang, P. P. & Ke, X., 2018, In : Journal of Physics Condensed Matter. 30, 29

Research output: Contribution to journalArticle

Transport properties
transport properties
Phase transitions

Topical rectal antiseptic at time of prostate biopsy: how a resident patient safety project has evolved into institutional practice

Park, R., Gyorfi, J., Dewan, K., Kirimanjeswara, G. S., Clark, J. Y., Kaag, M. G., Lehman, K. & Raman, J., Sep 1 2018, In : International Urology and Nephrology. 50, 9, p. 1563-1568 6 p.

Research output: Contribution to journalArticle

Institutional Practice
Local Anti-Infective Agents
Patient Safety
3 Citations (Scopus)

Urolithin a is a dietary microbiota-derived human aryl hydrocarbon receptor antagonist

Muku, G. E., Murray, I. A., Espín, J. C. & Perdew, G. H., Dec 1 2018, In : Metabolites. 8, 4

Research output: Contribution to journalArticle

Aryl Hydrocarbon Receptors
Competitive Binding
Caco-2 Cells
2 Citations (Scopus)

VISTA is highly expressed on MDSCs and mediates an inhibition of T cell response in patients with AML

Wang, L., Jia, B., Claxton, D., Ehmann, W. C., Rybka, W., Mineishi, S., Naik, S., Khawaja, M. R., Sivik, J., Han, J., Hohl, R. & Zheng, H., Sep 2 2018, In : OncoImmunology. 7, 9, e1469594.

Research output: Contribution to journalArticle

Acute Myeloid Leukemia
Myeloid-Derived Suppressor Cells
Immunoglobulin Domains
12 Citations (Scopus)
Vitamin A Deficiency
Vitamin A
7 Citations (Scopus)

Widespread and precise reprogramming of yeast protein-genome interactions in response to heat shock

Vinayachandran, V., Reja, R., Rossi, M., Park, B., Rieber, L., Mittal, C., Mahony, S. A. & Pugh, B. F., Mar 1 2018, In : Genome research. 28, 3, p. 357-366 10 p.

Research output: Contribution to journalArticle

Heat-Shock Response
Fungal Proteins
6 Citations (Scopus)

Accurate and reproducible functional maps in 127 human cell types via 2D genome segmentation

Zhang, Y. & Hardison, R. C., Sep 1 2017, In : Nucleic acids research. 45, 17, p. 9823-9836 14 p.

Research output: Contribution to journalArticle

Biomedical Research
14 Citations (Scopus)

Accurate nanoscale flexibility measurement of DNA and DNA-protein complexes by atomic force microscopy in liquid

Murugesapillai, D., Bouaziz, S., Maher, L. J., Israeloff, N. E., Cameron, C. E. & Williams, M. C., Aug 21 2017, In : Nanoscale. 9, 31, p. 11327-11337 11 p.

Research output: Contribution to journalArticle

Atomic force microscopy
Imaging techniques
19 Citations (Scopus)

Acoustofluidic bacteria separation

Li, S., Ma, F., Bachman, H., Cameron, C. E., Zeng, X. & Huang, T. J., Jan 1 2017, In : Journal of Micromechanics and Microengineering. 27, 1, 015031.

Research output: Contribution to journalArticle

Escherichia coli
23 Citations (Scopus)

Activation of intestinal hypoxia-inducible factor 2α during obesity contributes to hepatic steatosis

Xie, C., Yagai, T., Luo, Y., Liang, X., Chen, T., Wang, Q., Sun, D., Zhao, J., Ramakrishnan, S. K., Sun, L., Jiang, C., Xue, X., Tian, Y., Krausz, K. W., Patterson, A. D., Shah, Y. M., Wu, Y., Jiang, C. & Gonzalez, F. J., Nov 1 2017, In : Nature Medicine. 23, 11, p. 1298-1308 11 p.

Research output: Contribution to journalArticle

Chemical activation
6 Citations (Scopus)

Activation of PPARγ by endogenous prostaglandin J2 mediates the antileukemic effect of selenium in murine leukemia

Finch, E. R., Tukaramrao, D. B., Goodfield, L. L., Quickel, M. D., Paulson, R. & Prabhu, K. S., Mar 30 2017, In : Blood. 129, 13, p. 1802-1810 9 p.

Research output: Contribution to journalArticle

Peroxisome Proliferator-Activated Receptors
Chemical activation

Active Site Interactions Impact Phosphoryl Transfer during Replication of Damaged and Undamaged DNA by Escherichia coli DNA Polymerase i

Prakasha Gowda, A. S. & Spratt, T., Nov 20 2017, In : Chemical Research in Toxicology. 30, 11, p. 2033-2043 11 p.

Research output: Contribution to journalArticle

DNA-Directed DNA Polymerase
Escherichia coli
Catalytic Domain
38 Citations (Scopus)

Adult enteric nervous system in health is maintained by a dynamic balance between neuronal apoptosis and neurogenesis

Kulkarni, S., Micci, M. A., Leser, J., Shin, C., Tang, S. C., Fu, Y. Y., Liu, L., Li, Q., Saha, M., Li, C., Enikolopov, G., Becker, L., Rakhilin, N., Anderson, M., Shen, X., Dong, X., Butte, M. J., Song, H., Southard-Smith, E. M., Kapur, R. P. & 2 others, Bogunovic, M. & Pasricha, P. J., May 2 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 18, p. E3709-E3718

Research output: Contribution to journalArticle

Enteric Nervous System
10 Citations (Scopus)

AFB1 hepatocarcinogenesis is via lipid peroxidation that inhibits DNA repair, sensitizes mutation susceptibility and induces aldehyde-DNA adducts at p53 mutational hotspot codon 249

Weng, M. W., Lee, H. W., Choi, B., Wang, H. T., Hu, Y., Mehta, M., Desai, D., Amin, S., Zheng, Y. & Tang, M. S., Jan 1 2017, In : Oncotarget. 8, 11, p. 18213-18226 14 p.

Research output: Contribution to journalArticle

Aflatoxin B1
DNA Adducts
DNA Repair
10 Citations (Scopus)

A genome-wide CRISPR screen identifies genes critical for resistance to FLT3 inhibitor AC220

Hou, P., Wu, C., Wang, Y., Qi, R., Bhavanasi, D., Zuo, Z., Dos Santos, C., Chen, S., Chen, Y., Zheng, H., Wang, H., Perl, A., Guo, D. & Huang, J., Aug 15 2017, In : Cancer Research. 77, 16, p. 4402-4413 12 p.

Research output: Contribution to journalArticle

Clustered Regularly Interspaced Short Palindromic Repeats
Acute Myeloid Leukemia
Protein-Tyrosine Kinases
8 Citations (Scopus)

Ah receptor activation potentiates neutrophil chemoattractant (C-X-C Motif) ligand 5 expression in keratinocytes and skin

Smith, K. J., Boyer, J. A., Muku, G. E., Murray, I. A., Gowda, K., Desai, D., Amin, S., Glick, A. B. & Perdew, G. H., Jan 1 2017, In : Toxicological Sciences. 160, 1, p. 83-94 12 p.

Research output: Contribution to journalArticle

Aryl Hydrocarbon Receptors
Neutrophil Activation
Chemotactic Factors
2 Citations (Scopus)

Altered molecular profile in thyroid cancers from patients affected by the Three Mile Island nuclear accident

Goldenberg, D., Russo, M., Houser, K., Crist, H., Derr, J. B., Walter, V., Warrick, J., Sheldon, K. E., Broach, J. & Bann, D. V., Jul 1 2017, In : Laryngoscope. 127, p. S1-S9

Research output: Contribution to journalArticle

Radioactive Hazard Release
Thyroid Neoplasms
Gene Fusion
Radiation-Induced Neoplasms
21 Citations (Scopus)

A Multi-step Transcriptional and Chromatin State Cascade Underlies Motor Neuron Programming from Embryonic Stem Cells

Velasco, S., Ibrahim, M. M., Kakumanu, A., Garipler, G., Aydin, B., Al-Sayegh, M. A., Hirsekorn, A., Abdul-Rahman, F., Satija, R., Ohler, U., Mahony, S. A. & Mazzoni, E. O., Feb 2 2017, In : Cell Stem Cell. 20, 2, p. 205-217.e8

Research output: Contribution to journalArticle

Motor Neurons
Embryonic Stem Cells
Nucleic Acid Regulatory Sequences
Onecut Transcription Factors

An Efficient Synthesis of Dibenzo[a,l]tetracene and Dibenzo[a,j]tetracene and Their Identification in a Coal Tar Extract

Ramisetti, S. R., Oña-Ruales, J. O., Wise, S. A., Amin, S. & Sharma, A., Sep 8 2017, (Accepted/In press) In : Polycyclic Aromatic Compounds. p. 1-11 11 p.

Research output: Contribution to journalArticle

Coal Tar
Coal tar
Polycyclic Aromatic Hydrocarbons
Liquid chromatography
35 Citations (Scopus)

An intestinal farnesoid x receptor-ceramide signaling axis modulates hepatic gluconeogenesis in mice

Xie, C., Jiang, C., Shi, J., Gao, X., Sun, D., Sun, L., Wang, T., Takahashi, S., Anitha, M., Krausz, K. W., Patterson, A. D. & Gonzalez, F. J., Mar 1 2017, In : Diabetes. 66, 3, p. 613-626 14 p.

Research output: Contribution to journalArticle

Pyruvate Carboxylase
Acetyl-CoA Carboxylase
7 Citations (Scopus)

A non-cleavable hexahistidine affinity tag at the carboxyl-terminus of the HIV-1 Pr55Gag polyprotein alters nucleic acid binding properties

Bewley, M. C., Reinhart, L., Stake, M. S., Nadaraia-Hoke, S., Parent, L. J. & Flanagan, J. M., Feb 1 2017, In : Protein Expression and Purification. 130, p. 137-145 9 p.

Research output: Contribution to journalArticle

Nucleic Acids
4 Citations (Scopus)

A novel dual inhibitor of microtubule and Bruton's tyrosine kinase inhibits survival of multiple myeloma and osteoclastogenesis

Pandey, M. K., Gowda, K., Sung, S., Abraham, T., Budak-Alpdogan, T., Talamo, G., Dovat, S. & Amin, S., Sep 1 2017, In : Experimental Hematology. 53, p. 31-42 12 p.

Research output: Contribution to journalArticle

Multiple Myeloma
Cell Survival
3 Citations (Scopus)

Antibody competition reveals surface location of HPV L2 minor capsid protein residues 17–36

Bywaters, S. M., Brendle, S. A., Tossi, K. P., Biryukov, J., Meyers, C. & Christensen, N., Nov 10 2017, In : Viruses. 9, 11, 336.

Research output: Contribution to journalArticle

Capsid Proteins
Virus-Like Particle Vaccines
20 Citations (Scopus)

Application of NMR to studies of intrinsically disordered proteins

Gibbs, E. B., Cook, E. C. & Showalter, S. A., Aug 15 2017, In : Archives of Biochemistry and Biophysics. 628, p. 57-70 14 p.

Research output: Contribution to journalArticle

Intrinsically Disordered Proteins
Nuclear magnetic resonance
Nuclear magnetic resonance spectroscopy
Magnetic Resonance Spectroscopy
40 Citations (Scopus)

ARID1A-mutated ovarian cancers depend on HDAC6 activity

Bitler, B. G., Wu, S., Park, P. H., Hai, Y., Aird, K., Wang, Y., Zhai, Y., Kossenkov, A. V., Vara-Ailor, A., Rauscher, F. J., Zou, W., Speicher, D. W., Huntsman, D. G., Conejo-Garcia, J. R., Cho, K. R., Christianson, D. W. & Zhang, R., Aug 1 2017, In : Nature Cell Biology. 19, 8, p. 962-973 12 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Chromatin Assembly and Disassembly
19 Citations (Scopus)

A smartphone-based chloridometer for point-of-care diagnostics of cystic fibrosis

Zhang, C., Kim, J. P., Creer, M., Yang, J. & Liu, Z., Nov 15 2017, In : Biosensors and Bioelectronics. 97, p. 164-168 5 p.

Research output: Contribution to journalArticle

Point-of-Care Systems
Cystic Fibrosis
3 Citations (Scopus)
Functional groups
80 Citations (Scopus)

A subset of platinum-containing chemotherapeutic agents kills cells by inducing ribosome biogenesis stress

Bruno, P. M., Liu, Y., Park, G. Y., Murai, J., Koch, C. E., Eisen, T. J., Pritchard, J., Pommier, Y., Lippard, S. J. & Hemann, M. T., Apr 1 2017, In : Nature Medicine. 23, 4, p. 461-471 11 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

A systemic macrophage response is required to contain a peripheral poxvirus infection

Davies, M. L., Parekh, N. J., Kaminsky, L. W., Soni, C., Reider, I. E., Krouse, T. E., Fischer, M. A., van Rooijen, N., Rahman, Z. & Norbury, C., Jan 1 2017, In : PLoS Pathogens. 13, 6, e1006435.

Research output: Contribution to journalArticle

Poxviridae Infections
Vaccinia virus

Atypical parathyroid adenoma with diffuse fibrosis

Clark, C. M., Payne, S. J., Warrick, J. & Goldenberg, D., Jan 1 2017, In : Ear, Nose and Throat Journal. 96, 2, p. 57-58 2 p.

Research output: Contribution to journalArticle

Parathyroid Neoplasms
14 Citations (Scopus)

Bacterial siderophores hijack neutrophil functions

Saha, P., Yeoh, B. S., Olvera, R. A., Xiao, X., Singh, V., Awasthi, D., Subramanian, B. C., Chen, Q., Dikshit, M., Wang, Y., Parent, C. A. & Kumar, M. V., Jun 1 2017, In : Journal of Immunology. 198, 11, p. 4293-4303 11 p.

Research output: Contribution to journalArticle

Reactive Oxygen Species
3 Citations (Scopus)

Bioactive growth hormone in older men and women: It's relationship to immune markers and healthspan

Kraemer, W. J., Kennett, M. J., Mastro, A. M., McCarter, R. J., Rogers, C. J., DuPont, W. H., Flanagan, S. D., Turbitt, W. J., Fragala, M. S., Post, E. M. & Hymer, W. C., Jun 1 2017, In : Growth Hormone and IGF Research. 34, p. 45-54 10 p.

Research output: Contribution to journalArticle

Growth Hormone
Biological Assay
Tissue Donors