Research Output 1963 2020

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2018
6 Citations (Scopus)

The human ion channel TRPM2 modulates neuroblastoma cell survival and mitochondrial function through Pyk2, CREB, and MCU activation

Hirschler-Laszkiewicz, I., Chen, S. J., Bao, L., Wang, J., Zhang, X. Q., Shanmughapriya, S., Keefer, K., Madesh, M., Cheung, J. Y. & Miller, B. A., Oct 6 2018, In : American Journal of Physiology - Cell Physiology. 315, 4, p. C571-C586

Research output: Contribution to journalArticle

Focal Adhesion Kinase 2
Transient Receptor Potential Channels
Neuroblastoma
Ion Channels
Cell Survival
15 Citations (Scopus)

The human papillomavirus E6 oncoprotein targets USP15 and TRIM25 to suppress RIG-I-mediated innate immune signaling

Chiang, C., Pauli, E. K., Biryukov, J., Feister, K. F., Meng, M., White, E. A., Münger, K., Howley, P. M., Meyers, C. & Gack, M. U., Mar 1 2018, In : Journal of virology. 92, 6, e01737-17.

Research output: Contribution to journalArticle

Papillomaviridae
retinoic acid
Oncogene Proteins
Tretinoin
Genes
3 Citations (Scopus)

The SAGA/TREX-2 subunit Sus1 binds widely to transcribed genes and affects mRNA turnover globally

García-Molinero, V., García-Martínez, J., Reja, R., Furió-Tarí, P., Antúnez, O., Vinayachandran, V., Conesa, A., Pugh, B. F., Pérez-Ortín, J. E. & Rodríguez-Navarro, S., Mar 29 2018, In : Epigenetics and Chromatin. 11, 1, 13.

Research output: Contribution to journalArticle

Acetyltransferases
Transcription Factor TFIID
Messenger RNA
Yeasts
Genes
17 Citations (Scopus)

The store-operated calcium channels in cancer metastasis: from cell migration, invasion to metastatic colonization

Mo, P. & Yang, S., Jan 1 2018, In : Frontiers in Bioscience - Landmark. 23, 7, p. 1241-1256 16 p.

Research output: Contribution to journalArticle

Calcium Channels
Cell Movement
Neoplasm Metastasis
Calcium
Neoplasms
12 Citations (Scopus)

The wide utility of rabbits as models of human diseases

Esteves, P. J., Abrantes, J., Baldauf, H. M., BenMohamed, L., Chen, Y., Christensen, N., González-Gallego, J., Giacani, L., Hu, J., Kaplan, G., Keppler, O. T., Knight, K. L., Kong, X. P., Lanning, D. K., Le Pendu, J., De Matos, A. L., Liu, J., Liu, S., Lopes, A. M., Lu, S. & 17 others, Lukehart, S., Manabe, Y. C., Neves, F., McFadden, G., Pan, R., Peng, X., de Sousa-Pereira, P., Pinheiro, A., Rahman, M., Ruvoën-Clouet, N., Subbian, S., Tuñón, M. J., van der Loo, W., Vaine, M., Via, L. E., Wang, S. & Mage, R., May 2018, In : Experimental and Molecular Medicine. 50, 5, 66.

Research output: Contribution to journalArticle

Rabbits
Virus Diseases
Vaccines
Acquired Immunodeficiency Syndrome
Rabies Vaccines

Thickness evolution of transport properties in exfoliated Fe1+yTe nanoflakes

Hsieh, T-W., Zou, T., Hu, J., Mao, Z. Q., Zhang, P. P. & Ke, X., 2018, In : Journal of Physics Condensed Matter. 30, 29

Research output: Contribution to journalArticle

flakes
Magnetoresistance
Transport properties
transport properties
Phase transitions

Topical rectal antiseptic at time of prostate biopsy: how a resident patient safety project has evolved into institutional practice

Park, R., Gyorfi, J., Dewan, K., Kirimanjeswara, G. S., Clark, J. Y., Kaag, M. G., Lehman, K. & Raman, J., Sep 1 2018, In : International Urology and Nephrology. 50, 9, p. 1563-1568 6 p.

Research output: Contribution to journalArticle

Institutional Practice
Local Anti-Infective Agents
Patient Safety
Prostate
Biopsy
3 Citations (Scopus)

Urolithin a is a dietary microbiota-derived human aryl hydrocarbon receptor antagonist

Muku, G. E., Murray, I. A., Espín, J. C. & Perdew, G. H., Dec 2018, In : Metabolites. 8, 4

Research output: Contribution to journalArticle

Aryl Hydrocarbon Receptors
Microbiota
Ligands
Competitive Binding
Caco-2 Cells
4 Citations (Scopus)

VISTA is highly expressed on MDSCs and mediates an inhibition of T cell response in patients with AML

Wang, L., Jia, B., Claxton, D. F., Ehmann, W. C., Rybka, W. B., Mineishi, S., Naik, S., Khawaja, M. R., Sivik, J., Han, J., Hohl, R. J. & Zheng, H., Sep 2 2018, In : OncoImmunology. 7, 9, e1469594.

Research output: Contribution to journalArticle

Acute Myeloid Leukemia
T-Lymphocytes
Leukemia
Myeloid-Derived Suppressor Cells
Immunoglobulin Domains
12 Citations (Scopus)
Vitamin A Deficiency
Vitamin A
Metabolism
Homeostasis
Liver
9 Citations (Scopus)

Widespread and precise reprogramming of yeast protein-genome interactions in response to heat shock

Vinayachandran, V., Reja, R., Rossi, M. J., Park, B., Rieber, L., Mittal, C., Mahony, S. & Pugh, B. F., Mar 2018, In : Genome research. 28, 3, p. 357-366 10 p.

Research output: Contribution to journalArticle

Heat-Shock Response
Fungal Proteins
Genome
Shock
Nucleosomes
2017
8 Citations (Scopus)

Accurate and reproducible functional maps in 127 human cell types via 2D genome segmentation

Zhang, Y. & Hardison, R. C., Sep 1 2017, In : Nucleic acids research. 45, 17, p. 9823-9836 14 p.

Research output: Contribution to journalArticle

Epigenomics
Genome
Biomedical Research
Mutation
DNA
14 Citations (Scopus)

Accurate nanoscale flexibility measurement of DNA and DNA-protein complexes by atomic force microscopy in liquid

Murugesapillai, D., Bouaziz, S., Maher, L. J., Israeloff, N. E., Cameron, C. E. & Williams, M. C., Aug 21 2017, In : Nanoscale. 9, 31, p. 11327-11337 11 p.

Research output: Contribution to journalArticle

Atomic force microscopy
Proteins
Liquids
Imaging techniques
DNA
25 Citations (Scopus)

Acoustofluidic bacteria separation

Li, S., Ma, F., Bachman, H., Cameron, C. E., Zeng, X. & Huang, T. J., Jan 2017, In : Journal of Micromechanics and Microengineering. 27, 1, 015031.

Research output: Contribution to journalArticle

Bacteria
Blood
Escherichia coli
Labels
Cells
29 Citations (Scopus)

Activation of intestinal hypoxia-inducible factor 2α during obesity contributes to hepatic steatosis

Xie, C., Yagai, T., Luo, Y., Liang, X., Chen, T., Wang, Q., Sun, D., Zhao, J., Ramakrishnan, S. K., Sun, L., Jiang, C., Xue, X., Tian, Y., Krausz, K. W., Patterson, A. D., Shah, Y. M., Wu, Y., Jiang, C. & Gonzalez, F. J., Nov 1 2017, In : Nature Medicine. 23, 11, p. 1298-1308 11 p.

Research output: Contribution to journalArticle

Intestines
Obesity
Chemical activation
Liver
Ceramides
6 Citations (Scopus)

Activation of PPARγ by endogenous prostaglandin J2 mediates the antileukemic effect of selenium in murine leukemia

Finch, E. R., Tukaramrao, D. B., Goodfield, L. L., Quickel, M. D., Paulson, R. F. & Prabhu, K. S., Mar 30 2017, In : Blood. 129, 13, p. 1802-1810 9 p.

Research output: Contribution to journalArticle

Peroxisome Proliferator-Activated Receptors
Selenium
Leukemia
Prostaglandins
Chemical activation

Active Site Interactions Impact Phosphoryl Transfer during Replication of Damaged and Undamaged DNA by Escherichia coli DNA Polymerase i

Prakasha Gowda, A. S. & Spratt, T. E., Nov 20 2017, In : Chemical research in toxicology. 30, 11, p. 2033-2043 11 p.

Research output: Contribution to journalArticle

Guanine
DNA-Directed DNA Polymerase
Escherichia coli
Catalytic Domain
DNA
42 Citations (Scopus)

Adult enteric nervous system in health is maintained by a dynamic balance between neuronal apoptosis and neurogenesis

Kulkarni, S., Micci, M. A., Leser, J., Shin, C., Tang, S. C., Fu, Y. Y., Liu, L., Li, Q., Saha, M., Li, C., Enikolopov, G., Becker, L., Rakhilin, N., Anderson, M., Shen, X., Dong, X., Butte, M. J., Song, H., Southard-Smith, E. M., Kapur, R. P. & 2 others, Bogunovic, M. & Pasricha, P. J., May 2 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 18, p. E3709-E3718

Research output: Contribution to journalArticle

Enteric Nervous System
Neurogenesis
Apoptosis
Ganglia
Health
10 Citations (Scopus)

AFB1 hepatocarcinogenesis is via lipid peroxidation that inhibits DNA repair, sensitizes mutation susceptibility and induces aldehyde-DNA adducts at p53 mutational hotspot codon 249

Weng, M. W., Lee, H. W., Choi, B., Wang, H. T., Hu, Y., Mehta, M., Desai, D., Amin, S., Zheng, Y. & Tang, M. S., Jan 1 2017, In : Oncotarget. 8, 11, p. 18213-18226 14 p.

Research output: Contribution to journalArticle

Aflatoxin B1
DNA Adducts
Aldehydes
Codon
DNA Repair
11 Citations (Scopus)

A genome-wide CRISPR screen identifies genes critical for resistance to FLT3 inhibitor AC220

Hou, P., Wu, C., Wang, Y., Qi, R., Bhavanasi, D., Zuo, Z., Dos Santos, C., Chen, S., Chen, Y., Zheng, H., Wang, H., Perl, A., Guo, D. & Huang, J., Aug 15 2017, In : Cancer Research. 77, 16, p. 4402-4413 12 p.

Research output: Contribution to journalArticle

Clustered Regularly Interspaced Short Palindromic Repeats
Acute Myeloid Leukemia
Protein-Tyrosine Kinases
Genome
Genes
8 Citations (Scopus)

Ah receptor activation potentiates neutrophil chemoattractant (C-X-C Motif) ligand 5 expression in keratinocytes and skin

Smith, K. J., Boyer, J. A., Muku, G. E., Murray, I. A., Gowda, K., Desai, D., Amin, S. G., Glick, A. B. & Perdew, G. H., Jan 1 2017, In : Toxicological Sciences. 160, 1, p. 83-94 12 p.

Research output: Contribution to journalArticle

Aryl Hydrocarbon Receptors
Neutrophil Activation
Chemotactic Factors
Keratinocytes
Skin
2 Citations (Scopus)

Altered molecular profile in thyroid cancers from patients affected by the Three Mile Island nuclear accident

Goldenberg, D., Russo, M., Houser, K., Crist, H., Derr, J. B., Walter, V., Warrick, J. I., Sheldon, K. E., Broach, J. & Bann, D. V., Jul 2017, In : Laryngoscope. 127, p. S1-S9

Research output: Contribution to journalArticle

Radioactive Hazard Release
Thyroid Neoplasms
Islands
Gene Fusion
Radiation-Induced Neoplasms
24 Citations (Scopus)

A Multi-step Transcriptional and Chromatin State Cascade Underlies Motor Neuron Programming from Embryonic Stem Cells

Velasco, S., Ibrahim, M. M., Kakumanu, A., Garipler, G., Aydin, B., Al-Sayegh, M. A., Hirsekorn, A., Abdul-Rahman, F., Satija, R., Ohler, U., Mahony, S. & Mazzoni, E. O., Feb 2 2017, In : Cell Stem Cell. 20, 2, p. 205-217.e8

Research output: Contribution to journalArticle

Motor Neurons
Embryonic Stem Cells
Chromatin
Nucleic Acid Regulatory Sequences
Onecut Transcription Factors

An Efficient Synthesis of Dibenzo[a,l]tetracene and Dibenzo[a,j]tetracene and Their Identification in a Coal Tar Extract

Ramisetti, S. R., Oña-Ruales, J. O., Wise, S. A., Amin, S. & Sharma, A. K., Sep 8 2017, (Accepted/In press) In : Polycyclic Aromatic Compounds. p. 1-11 11 p.

Research output: Contribution to journalArticle

Coal Tar
Coal tar
Aromatization
Polycyclic Aromatic Hydrocarbons
Liquid chromatography
43 Citations (Scopus)

An intestinal farnesoid x receptor-ceramide signaling axis modulates hepatic gluconeogenesis in mice

Xie, C., Jiang, C., Shi, J., Gao, X., Sun, D., Sun, L., Wang, T., Takahashi, S., Anitha, M., Krausz, K. W., Patterson, A. D. & Gonzalez, F. J., Mar 1 2017, In : Diabetes. 66, 3, p. 613-626 14 p.

Research output: Contribution to journalArticle

Gluconeogenesis
Ceramides
Liver
Pyruvate Carboxylase
Acetyl-CoA Carboxylase
8 Citations (Scopus)

A non-cleavable hexahistidine affinity tag at the carboxyl-terminus of the HIV-1 Pr55Gag polyprotein alters nucleic acid binding properties

Bewley, M. C., Reinhart, L., Stake, M. S., Nadaraia-Hoke, S., Parent, L. J. & Flanagan, J. M., Feb 1 2017, In : Protein Expression and Purification. 130, p. 137-145 9 p.

Research output: Contribution to journalArticle

His-His-His-His-His-His
Polyproteins
Nucleic Acids
HIV-1
HIV
4 Citations (Scopus)

A novel dual inhibitor of microtubule and Bruton's tyrosine kinase inhibits survival of multiple myeloma and osteoclastogenesis

Pandey, M. K., Gowda, K., Sung, S. S., Abraham, T., Budak-Alpdogan, T., Talamo, G., Dovat, S. & Amin, S., Sep 2017, In : Experimental Hematology. 53, p. 31-42 12 p.

Research output: Contribution to journalArticle

Multiple Myeloma
Osteogenesis
Microtubules
Polymerization
Cell Survival
3 Citations (Scopus)

Antibody competition reveals surface location of HPV L2 minor capsid protein residues 17–36

Bywaters, S. M., Brendle, S. A., Tossi, K. P., Biryukov, J., Meyers, C. & Christensen, N. D., Nov 10 2017, In : Viruses. 9, 11, 336.

Research output: Contribution to journalArticle

Capsid Proteins
Epitopes
Antibodies
Capsid
Virus-Like Particle Vaccines
22 Citations (Scopus)

Application of NMR to studies of intrinsically disordered proteins

Gibbs, E. B., Cook, E. C. & Showalter, S. A., Aug 15 2017, In : Archives of Biochemistry and Biophysics. 628, p. 57-70 14 p.

Research output: Contribution to journalArticle

Intrinsically Disordered Proteins
Nuclear magnetic resonance
Nuclear magnetic resonance spectroscopy
Magnetic Resonance Spectroscopy
Proteins
49 Citations (Scopus)

ARID1A-mutated ovarian cancers depend on HDAC6 activity

Bitler, B. G., Wu, S., Park, P. H., Hai, Y., Aird, K., Wang, Y., Zhai, Y., Kossenkov, A. V., Vara-Ailor, A., Rauscher, F. J., Zou, W., Speicher, D. W., Huntsman, D. G., Conejo-Garcia, J. R., Cho, K. R., Christianson, D. W. & Zhang, R., Aug 1 2017, In : Nature Cell Biology. 19, 8, p. 962-973 12 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Neoplasms
Apoptosis
Mutation
Chromatin Assembly and Disassembly
19 Citations (Scopus)

A smartphone-based chloridometer for point-of-care diagnostics of cystic fibrosis

Zhang, C., Kim, J. P., Creer, M., Yang, J. & Liu, Z., Nov 15 2017, In : Biosensors and Bioelectronics. 97, p. 164-168 5 p.

Research output: Contribution to journalArticle

Point-of-Care Systems
Smartphones
Cystic Fibrosis
Chlorides
Sweat
4 Citations (Scopus)
Hydrocarbons
Cells
Bromine
Isomers
Functional groups
91 Citations (Scopus)

A subset of platinum-containing chemotherapeutic agents kills cells by inducing ribosome biogenesis stress

Bruno, P. M., Liu, Y., Park, G. Y., Murai, J., Koch, C. E., Eisen, T. J., Pritchard, J. R., Pommier, Y., Lippard, S. J. & Hemann, M. T., Apr 1 2017, In : Nature Medicine. 23, 4, p. 461-471 11 p.

Research output: Contribution to journalArticle

oxaliplatin
Platinum
Ribosomes
Cisplatin
Carboplatin
3 Citations (Scopus)

A systemic macrophage response is required to contain a peripheral poxvirus infection

Davies, M. L., Parekh, N. J., Kaminsky, L. W., Soni, C., Reider, I. E., Krouse, T. E., Fischer, M. A., van Rooijen, N., Rahman, Z. S. M. & Norbury, C. C., Jan 1 2017, In : PLoS pathogens. 13, 6, e1006435.

Research output: Contribution to journalArticle

Poxviridae Infections
Vaccinia virus
Macrophages
Infection
Viruses

Atypical parathyroid adenoma with diffuse fibrosis

Clark, C. M., Payne, S. J., Warrick, J. & Goldenberg, D., Jan 1 2017, In : Ear, Nose and Throat Journal. 96, 2, p. 57-58 2 p.

Research output: Contribution to journalArticle

Parathyroid Neoplasms
Fibrosis
17 Citations (Scopus)

Bacterial siderophores hijack neutrophil functions

Saha, P., Yeoh, B. S., Olvera, R. A., Xiao, X., Singh, V., Awasthi, D., Subramanian, B. C., Chen, Q., Dikshit, M., Wang, Y., Parent, C. A. & Vijay-Kumar, M., Jun 1 2017, In : Journal of Immunology. 198, 11, p. 4293-4303 11 p.

Research output: Contribution to journalArticle

Siderophores
Neutrophils
Enterobactin
Iron
Reactive Oxygen Species
4 Citations (Scopus)

Bioactive growth hormone in older men and women: It's relationship to immune markers and healthspan

Kraemer, W. J., Kennett, M. J., Mastro, A. M., McCarter, R. J., Rogers, C. J., DuPont, W. H., Flanagan, S. D., Turbitt, W. J., Fragala, M. S., Post, E. M. & Hymer, W. C., Jun 1 2017, In : Growth Hormone and IGF Research. 34, p. 45-54 10 p.

Research output: Contribution to journalArticle

Growth Hormone
Biomarkers
Immunoassay
Biological Assay
Tissue Donors
12 Citations (Scopus)

Blimp-1 impairs T cell function via upregulation of TIGIT and PD-1 in patients with acute myeloid leukemia

Zhu, L., Kong, Y., Zhang, J., Claxton, D. F., Ehmann, W. C., Rybka, W. B., Palmisiano, N. D., Wang, M., Jia, B., Bayerl, M., Schell, T. D., Hohl, R. J., Zeng, H. & Zheng, H., Jun 19 2017, In : Journal of Hematology and Oncology. 10, 1, 124.

Research output: Contribution to journalArticle

Acute Myeloid Leukemia
B-Lymphocytes
Up-Regulation
T-Lymphocytes
Proteins
25 Citations (Scopus)

Cancer-FOXP3 directly activated CCL5 to recruit FOXP3 + Treg cells in pancreatic ductal adenocarcinoma

Wang, X., Lang, M., Zhao, T., Feng, X., Zheng, C., Huang, C., Hao, J., Dong, J., Luo, L., Li, X., Lan, C., Yu, W., Yu, M., Yang, S. & Ren, H., May 25 2017, In : Oncogene. 36, 21, p. 3048-3058 11 p.

Research output: Contribution to journalArticle

Transcription Factor 3
Regulatory T-Lymphocytes
Adenocarcinoma
Neoplasms
Proteins
17 Citations (Scopus)

Capsid phosphorylation state and hepadnavirus virion secretion

Ning, X., Basagoudanavar, S. H., Liu, K., Luckenbaugh, L., Wei, D., Wang, C., Wei, B., Zhao, Y., Yan, T., Delaney, W. & Hu, J., May 1 2017, In : Journal of virology. 91, 9, e00092-17.

Research output: Contribution to journalArticle

Hepadnaviridae
capsid
Capsid
virion
Virion

Catching global interactions in vivo

Qiu, Y. & Huang, S., Sep 29 2017, In : Cell and Bioscience. 7, 1, 49.

Research output: Contribution to journalArticle

Proteins
Transcription Factors
Histones
Protein Sequence Analysis
Genes
Technical presentations
conversation
Innovation
Students
engineering
14 Citations (Scopus)

Chimeric L2-based virus-like particle (VLP) vaccines targeting cutaneous human papillomaviruses (HPV)

Huber, B., Schellenbacher, C., Shafti-Keramat, S., Jindra, C., Christensen, N. & Kirnbauer, R., Jan 2017, In : PloS one. 12, 1, 0169533.

Research output: Contribution to journalArticle

Virus-Like Particle Vaccines
virus-like particle vaccines
Papillomaviridae
virus-like particles
Viruses
8 Citations (Scopus)

CitH3: A reliable blood biomarker for diagnosis and treatment of endotoxic shock

Pan, B., Alam, H. B., Chong, W., Mobley, J., Liu, B., Deng, Q., Liang, Y., Wang, Y., Chen, E., Wang, T., Tewari, M. & Li, Y., Dec 1 2017, In : Scientific reports. 7, 1, 8972.

Research output: Contribution to journalArticle

Septic Shock
Histones
Biomarkers
Lipopolysaccharides
Hemorrhagic Shock
3 Citations (Scopus)

Clinical significance of prominent retraction clefts in invasive urothelial carcinoma

Shah, T. S., Kaag, M. G., Raman, J., Chan, W., Tran, T., Kunchala, S., Shuman, L., Degraff, D., Chen, G. & Warrick, J., Mar 1 2017, In : Human Pathology. 61, p. 90-96 7 p.

Research output: Contribution to journalArticle

Carcinoma
Lymph Nodes
Neoplasm Metastasis
Cystectomy
Neoplasms
8 Citations (Scopus)
Clonal Evolution
Endometrioid Carcinoma
Endometrial Hyperplasia
Hyperplasia
Endometrial Neoplasms
5 Citations (Scopus)

C‐Myc‐induced survivin is essential for promoting the Notch-dependent t cell differentiation from hematopoietic stem cells

Haque, R., Song, J., Haque, M., Lei, F., Sandhu, P., Ni, B., Zheng, S., Fang, D., Yang, J. M. & Song, J., Mar 2017, In : Genes. 8, 3, 97.

Research output: Contribution to journalArticle

Hematopoietic Stem Cells
Cell Differentiation
T-Lymphocytes
Cell Lineage
Inhibitor of Apoptosis Proteins
13 Citations (Scopus)

Comparison of Metabolomics Approaches for Evaluating the Variability of Complex Botanical Preparations: Green Tea (Camellia sinensis) as a Case Study

Kellogg, J. J., Graf, T. N., Paine, M. F., McCune, J. S., Kvalheim, O. M., Oberlies, N. H. & Cech, N. B., May 26 2017, In : Journal of Natural Products. 80, 5, p. 1457-1466 10 p.

Research output: Contribution to journalArticle

Open Access
Camellia sinensis
Metabolomics
Tea
Liquid chromatography
Liquid Chromatography
11 Citations (Scopus)

Control of circulating IgE by the Vitamin D receptor in vivo involves B cell intrinsic and extrinsic mechanisms

James, J., Weaver, V. & Cantorna, M. T., Feb 1 2017, In : Journal of Immunology. 198, 3, p. 1164-1171 8 p.

Research output: Contribution to journalArticle

Calcitriol Receptors
Immunoglobulin E
B-Lymphocytes
Knockout Mice
Vitamin D
7 Citations (Scopus)

Conventional and accelerated-solvent extractions of green tea (camellia sinensis) for metabolomics-based chemometrics

Kellogg, J. J., Wallace, E. D., Graf, T. N., Oberlies, N. H. & Cech, N. B., Oct 25 2017, In : Journal of Pharmaceutical and Biomedical Analysis. 145, p. 604-610 7 p.

Research output: Contribution to journalArticle

Camellia sinensis
Metabolomics
Solvent extraction
Tea
Theaceae