Research Output 1963 2019

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2017
6 Citations (Scopus)

FOXA1 and CK14 as markers of luminal and basal subtypes in histologic variants of bladder cancer and their associated conventional urothelial carcinoma

Warrick, J., Kaag, M. G., Raman, J., Chan, W., Tran, T., Kunchala, S., Shuman, L., Degraff, D. & Chen, G., Sep 1 2017, In : Virchows Archiv. 471, 3, p. 337-345 9 p.

Research output: Contribution to journalArticle

Urinary Bladder Neoplasms
Carcinoma
Squamous Cell Carcinoma
Histology
Cystectomy
7 Citations (Scopus)

GATA Factor-Regulated Samd14 Enhancer Confers Red Blood Cell Regeneration and Survival in Severe Anemia

Hewitt, K. J., Katsumura, K. R., Matson, D. R., Devadas, P., Tanimura, N., Hebert, A. S., Coon, J. J., Kim, J. S., Dewey, C. N., Keles, S., Hao, S., Paulson, R. F. & Bresnick, E. H., Aug 7 2017, In : Developmental Cell. 42, 3, p. 213-225.e4

Research output: Contribution to journalArticle

GATA Transcription Factors
Anemia
Regeneration
Cell Survival
Blood
7 Citations (Scopus)

Genome-wide uniformity of human 'open' pre-initiation complexes

Lai, W. & Pugh, B. F., Jan 1 2017, In : Genome research. 27, 1, p. 15-26 12 p.

Research output: Contribution to journalArticle

Genome
Peptide Initiation Factors
Nucleosomes
Chromatin Immunoprecipitation
DNA
2 Citations (Scopus)

Golgi-associated protein kinase C-ϵ is delivered to phagocytic cups: Role of phosphatidylinositol 4-phosphate

Hanes, C. M., D'Amico, A. E., Ueyama, T., Wong, A. C., Zhang, X., Hynes, W. F., Barroso, M. M., Cady, N. C., Trebak, M., Saito, N. & Lennartz, M. R., Jul 1 2017, In : Journal of Immunology. 199, 1, p. 271-277 7 p.

Research output: Contribution to journalArticle

Protein Kinase C
trans-Golgi Network
Phagocytosis
Membrane Fusion
Phosphotransferases
10 Citations (Scopus)

HIF-2-dependent expression of stem cell factor promotes metastasis in hepatocellular carcinoma

Wang, X., Dong, J., Jia, L., Zhao, T., Lang, M., Li, Z., Lan, C., Li, X., Hao, J., Wang, H., Qin, T., Huang, C., Yang, S., Yu, M. & Ren, H., May 1 2017, In : Cancer Letters. 393, p. 113-124 12 p.

Research output: Contribution to journalArticle

Stem Cell Factor
Hepatocellular Carcinoma
Neoplasm Metastasis
Chromatin Immunoprecipitation
Response Elements
1 Citation (Scopus)

High-resolution structure analysis of antibody V5 and U4 conformational epitopes on human papillomavirus 16

Guan, J., Bywaters, S. M., Brendle, S. A., Ashley, R. E., Makhov, A. M., Conway, J. F., Christensen, N. & Hafenstein, S., Dec 6 2017, In : Viruses. 9, 12, 374.

Research output: Contribution to journalArticle

Human papillomavirus 16
Capsid
Immunoglobulin Fragments
Epitopes
Viral Structures
4 Citations (Scopus)

Histone deacetylase 1 activates PU.1 gene transcription through regulating TAF9 deacetylation and transcription factor IID assembly

Jian, W., Yan, B., Huang, S. & Qiu, Y., Sep 2017, In : FASEB Journal. 31, 9, p. 4104-4116 13 p.

Research output: Contribution to journalArticle

Histone Deacetylase 1
Transcription Factor TFIID
Transcription
Histone Deacetylases
Genes
5 Citations (Scopus)

Histone deacetylase 6 regulates cytokinesis and erythrocyte enucleation through deacetylation of formin protein mDia2

Li, X., Mei, Y., Yan, B., Vitriol, E., Huang, S., Ji, P. & Qiu, Y., Jan 1 2017, In : Haematologica. 102, 6, p. 984-994 11 p.

Research output: Contribution to journalArticle

Histone Deacetylases
Cytokinesis
Actins
Erythrocytes
Erythroblasts
7 Citations (Scopus)

Honey bee deformed wing virus structures reveal that conformational changes accompany genome release

Organtini, L. J., Shingler, K. L., Ashley, R. E., Capaldi, E. A., Durrani, K., Dryden, K. A., Makhov, A. M., Conway, J. F., Pizzorno, M. C. & Hafenstein, S., Jan 1 2017, In : Journal of virology. 91, 2, e01795-16.

Research output: Contribution to journalArticle

Deformed wing virus
viral morphology
Viral Structures
Honey
Bees
4 Citations (Scopus)

Honokiol Inhibits DNA Polymerases β and λ and Increases Bleomycin Sensitivity of Human Cancer Cells

Gowda, A. S. P., Suo, Z. & Spratt, T., Feb 20 2017, In : Chemical Research in Toxicology. 30, 2, p. 715-725 11 p.

Research output: Contribution to journalArticle

Bleomycin
DNA-Directed DNA Polymerase
temozolomide
Cells
Repair
5 Citations (Scopus)

HVEM imprints memory potential on effector CD8 T cells required for protective mucosal immunity

Desai, P., Abboud, G., Stanfield, J., Thomas, P. G., Song, J., Ware, C. F., Croft, M. & Salek-Ardakani, S., Oct 15 2017, In : Journal of Immunology. 199, 8, p. 2968-2975 8 p.

Research output: Contribution to journalArticle

Mucosal Immunity
T-Lymphocytes
Virus Internalization
Adoptive Transfer
Tumor Necrosis Factor Receptors
5 Citations (Scopus)
Tobacco
Mouth Neoplasms
Biomarkers
carcinogens
Early Detection of Cancer
3 Citations (Scopus)

Identification of a mouse Lactobacillus johnsonii strain with deconjugase activity against the FXR antagonist T-β-MCA

DiMarzio, M., Rusconi, B., Yennawar, N., Eppinger, M., Patterson, A. D. & Dudley, E. G., Sep 1 2017, In : PloS one. 12, 9, e0183564.

Research output: Contribution to journalArticle

choloylglycine hydrolase
Lactobacillus johnsonii
beta acids
antagonists
receptors
9 Citations (Scopus)

Identification of an intermediate in hepatitis B virus covalently closed circular (CCC) DNA formation and sensitive and selective CCC DNA detection

Luo, J., Cui, X., Gao, L. & Hu, J., Sep 1 2017, In : Journal of virology. 91, 17, e00539-17.

Research output: Contribution to journalArticle

circular DNA
Circular DNA
Hepatitis B virus
spleen exonuclease
DNA
8 Citations (Scopus)

Identification of a rare LAMB4 variant associated with familial diverticulitis through exome sequencing

Coble, J. L., Yue, F., Salameh, T. J., Harris, L. R., Deiling, S., Ruggiero, F. M., Eshelman, M. A., Yochum, G. S., Koltun, W. A., Gerhard, G. S. & Broach, J. R., Aug 15 2017, In : Human Molecular Genetics. 26, 16, p. 3212-3220 9 p., ddx204.

Research output: Contribution to journalArticle

Exome
Diverticulitis
Enteric Nervous System
Laminin
Genes
4 Citations (Scopus)

Identifying gene–gene interactions that are highly associated with four quantitative lipid traits across multiple cohorts

De, R., Verma, S. S., Holzinger, E., Hall, M., Burt, A., Carrell, D. S., Crosslin, D. R., Jarvik, G. P., Kuivaniemi, H., Kullo, I. J., Lange, L. A., Lanktree, M. B., Larson, E. B., North, K. E., Reiner, A. P., Tragante, V., Tromp, G., Wilson, J. G., Asselbergs, F. W., Drenos, F. & 4 others, Moore, J. H., Ritchie, M. D., Keating, B. & Gilbert-Diamond, D., Feb 1 2017, In : Human genetics. 136, 2, p. 165-178 14 p.

Research output: Contribution to journalArticle

Triglycerides
LDL Cholesterol
HDL Cholesterol
Lipids
Multifactor Dimensionality Reduction
8 Citations (Scopus)

Identifying the structure-activity relationship of leelamine necessary for inhibiting intracellular cholesterol transport

Gowda, R., Inamdar, G. S., Kuzu, O., Dinavahi, S. S., Krzeminski, J., Battu, M. B., Voleti, S. R., Amin, S. & Robertson, G., Jan 1 2017, In : Oncotarget. 8, 17, p. 28260-28277 18 p.

Research output: Contribution to journalArticle

Structure-Activity Relationship
Cholesterol
Lysosomes
Neoplasms
Computer Simulation
3 Citations (Scopus)

IL-4 up-regulates cyclooxygenase-1 expression in macrophages

Shay, A. E., Diwakar, B. T., Guan, B. J., Narayan, V., Urban, J. F. & Prabhu, K. S., Jan 1 2017, In : Journal of Biological Chemistry. 292, 35, p. 14544-14555 12 p.

Research output: Contribution to journalArticle

Cyclooxygenase 1
Macrophages
Interleukin-4
Up-Regulation
Sirolimus
1 Citation (Scopus)

Immune and metabolic responses in early and late sepsis during mild dietary zinc restriction

Crowell, K. T., Phillips, B. E., Kelleher, S. L., Soybel, D. I. & Lang, C. H., Apr 1 2017, In : Journal of Surgical Research. 210, p. 47-58 12 p.

Research output: Contribution to journalArticle

Zinc
Sepsis
Liver
Punctures
Interferon-gamma
5 Citations (Scopus)

Incorporation of RG1 epitope concatemers into a self-adjuvanting Flagellin-L2 vaccine broaden durable protection against cutaneous challenge with diverse human papillomavirus genotypes

Kalnin, K., Chivukula, S., Tibbitts, T., Yan, Y., Stegalkina, S., Shen, L., Cieszynski, J., Costa, V., Sabharwal, R., Anderson, S. F., Christensen, N., Jagu, S., Roden, R. B. S. & Kleanthous, H., Sep 5 2017, In : Vaccine. 35, 37, p. 4942-4951 10 p.

Research output: Contribution to journalArticle

Flagellin
flagellin
Papillomaviridae
epitopes
Epitopes
10 Citations (Scopus)

Indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors activate the aryl hydrocarbon receptor

Moyer, B. J., Rojas, I. Y., Murray, I. A., Lee, S., Hazlett, H. F., Perdew, G. H. & Tomlinson, C. R., May 15 2017, In : Toxicology and Applied Pharmacology. 323, p. 74-80 7 p.

Research output: Contribution to journalArticle

Indoleamine-Pyrrole 2,3,-Dioxygenase
Aryl Hydrocarbon Receptors
Tryptophan
Assays
Clinical Trials
5 Citations (Scopus)

Inhibition of retrograde transport limits polyomavirus infection in vivo

Maru, S., Jin, G., Desai, D., Amin, S., Shwetank, Lauver, M. D. & Lukacher, A., Nov 1 2017, In : mSphere. 2, 6, e00494-17.

Research output: Contribution to journalArticle

Polyomavirus Infections
Polyomavirus
BK Virus
JC Virus
Kidney
52 Citations (Scopus)

Intermittent Fasting Promotes White Adipose Browning and Decreases Obesity by Shaping the Gut Microbiota

Li, G., Xie, C., Lu, S., Nichols, R. G., Tian, Y., Li, L., Patel, D., Ma, Y., Brocker, C. N., Yan, T., Krausz, K. W., Xiang, R., Gavrilova, O., Patterson, A. D. & Gonzalez, F. J., Oct 3 2017, In : Cell Metabolism. 26, 4, p. 672-685.e4

Research output: Contribution to journalArticle

Fasting
Obesity
Microbiota
White Adipose Tissue
Metabolic Diseases
17 Citations (Scopus)

Intestinal Farnesoid X Receptor Signaling Modulates Metabolic Disease

Gonzalez, F. J., Jiang, C., Xie, C. & Patterson, A. D., Mar 1 2017, In : Digestive Diseases. 35, 3, p. 178-184 7 p.

Research output: Contribution to journalArticle

Metabolic Diseases
Ceramides
Intestines
Bile Acids and Salts
Ileum
1 Citation (Scopus)

Ionizing radiation promotes CCL27 secretion from keratinocytes through the cross talk between TNF-α and ROS

Zhang, Q., Zhu, L., Wang, G., Zhao, Y., Xiong, N., Bao, H. & Jin, W., Mar 1 2017, In : Journal of Biochemical and Molecular Toxicology. 31, 3, e21868.

Research output: Contribution to journalArticle

Ionizing radiation
Ionizing Radiation
Keratinocytes
Reactive Oxygen Species
Tumor Necrosis Factor-alpha
3 Citations (Scopus)

Isolation, characterization, and purification of macrophages from tissues affected by obesity-related inflammation

Allen, J. N., Dey, A., Nissly, R., Fraser, J., Yu, S., Balandaram, G., Peters, J. M. & Giblin, P. H., Apr 3 2017, In : Journal of Visualized Experiments. 2017, 122, e55445.

Research output: Contribution to journalArticle

Macrophages
Purification
Obesity
Tissue
Inflammation
3 Citations (Scopus)

Ligand-mediated cytoplasmic retention of the Ah receptor inhibits macrophage-mediated acute inflammatory responses

Muku, G. E., Lahoti, T. S., Murray, I. A., Podolsky, M. A., Smith, K. J., Hubbard, T. D., Kuzu, G., Gowda, K., Amin, S. G. & Perdew, G. H., Dec 1 2017, In : Laboratory Investigation. 97, 12, p. 1471-1487 17 p.

Research output: Contribution to journalArticle

Macrophages
Ligands
Uric Acid
Lipopolysaccharides
Inflammation
2 Citations (Scopus)
Lipogenesis
Emulsions
Running
Carbohydrates
Diet

Lipopolysacharide gene based development and optimization of diagnostics for francisella tularensis

Muhammad, J., Rabbani, M., Muhammad, K., Wasim, M., Dewan, K., Anjum, A. A., Sheikh, A. A., Ahmad, A., Akhtar, F., Nisar, M., Jayarao, B. M. & Kirimanjeswara, G. S., Jan 1 2017, In : Journal of Animal and Plant Sciences. 27, 4, p. 1161-1166 6 p.

Research output: Contribution to journalArticle

Francisella tularensis
developing countries
biocontainment
genes
annealing
20 Citations (Scopus)

Maintenance of PD-1 on brain-resident memory CD8 T cells is antigen independent

Shwetank, Abdelsamed, H. A., Frost, E. L., Schmitz, H. M., Mockus, T. E., Youngblood, B. A. & Lukacher, A., Nov 1 2017, In : Immunology and Cell Biology. 95, 10, p. 953-959 7 p.

Research output: Contribution to journalArticle

Polyomavirus
Maintenance
Programmed Cell Death 1 Receptor
T-Lymphocytes
Antigens
1 Citation (Scopus)

Mapping of functional subdomains in the terminal protein domain of hepatitis B virus polymerase

Clark, D. N., Flanagan, J. & Hu, J., Jan 1 2017, In : Journal of virology. 91, 3, e01785-16.

Research output: Contribution to journalArticle

Hepatitis B virus
Proteins
proteins
RNA
Mutagenesis
14 Citations (Scopus)

Merkel cell polyomavirus small T antigen induces genome instability by E3 ubiquitin ligase targeting

Kwun, H. J., Wendzicki, J. A., Shuda, Y., Moore, P. S. & Chang, Y., Jan 1 2017, In : Oncogene. 36, 49, p. 6784-6792 9 p.

Research output: Contribution to journalArticle

Merkel cell polyomavirus
Polyomavirus Transforming Antigens
Ubiquitin-Protein Ligases
Genomic Instability
Oncogene Proteins
9 Citations (Scopus)

MiniMDS: 3D structural inference from high-resolution Hi-C data

Rieber, L. & Mahony, S. A., Jul 15 2017, In : Bioinformatics. 33, 14, p. i261-i266

Research output: Contribution to journalArticle

High Resolution
Genes
Partition
Scaling
Data storage equipment
16 Citations (Scopus)

Mitochondria control store-operated Ca2+ entry through Na+ and redox signals

Ben-Kasus Nissim, T., Zhang, X., Elazar, A., Roy, S., Stolwijk, J. A., Zhou, Y., Motiani, R. K., Gueguinou, M., Hempel, N., Hershfinkel, M., Gill, D., Trebak, M. & Sekler, I., Mar 15 2017, In : EMBO Journal. 36, 6, p. 797-815 19 p.

Research output: Contribution to journalArticle

Mitochondria
Inventory control
Oxidation-Reduction
Cell membranes
Ion Channels
55 Citations (Scopus)

Mitochondrial Ca2+ Uniporter Is a Mitochondrial Luminal Redox Sensor that Augments MCU Channel Activity

Dong, Z., Shanmughapriya, S., Tomar, D., Siddiqui, N., Lynch, S., Nemani, N., Breves, S. L., Zhang, X., Tripathi, A., Palaniappan, P., Riitano, M. F., Worth, A. M., Seelam, A., Carvalho, E., Subbiah, R., Jaña, F., Soboloff, J., Peng, Y., Cheung, J. Y., Joseph, S. K. & 4 others, Caplan, J., Rajan, S., Stathopulos, P. B. & Madesh, M., Mar 16 2017, In : Molecular cell. 65, 6, p. 1014-1028.e7

Research output: Contribution to journalArticle

Open Access
Oxidation-Reduction
Cysteine
Sulfhydryl Compounds
Energy Metabolism
Signal Transduction
6 Citations (Scopus)

Modulation of urinary siderophores by the diet, gut microbiota and inflammation in mice

Xiao, X., Yeoh, B. S., Saha, P., Tian, Y., Singh, V., Patterson, A. D. & Kumar, M. V., Mar 1 2017, In : Journal of Nutritional Biochemistry. 41, p. 25-33 9 p.

Research output: Contribution to journalArticle

Siderophores
Nutrition
Modulation
Diet
Inflammation
4 Citations (Scopus)

Monitoring the Retention of Human Proliferating Cell Nuclear Antigen at Primer/Template Junctions by Proteins That Bind Single-Stranded DNA

Hedglin, M., Aitha, M. & Benkovic, S., Jul 11 2017, In : Biochemistry. 56, 27, p. 3415-3421 7 p.

Research output: Contribution to journalArticle

Single-Stranded DNA
Proliferating Cell Nuclear Antigen
Monitoring
DNA
Proteins
1 Citation (Scopus)

MOPS and coxsackievirus B3 stability

Carson, S. D., Hafenstein, S. & Lee, H., Jan 15 2017, In : Virology. 501, p. 183-187 5 p.

Research output: Contribution to journalArticle

Enterovirus
Viruses
Molecular Computers
Sulfonic Acids
Capsid
3 Citations (Scopus)

Mouse papillomavirus infection persists in mucosal tissues of an immunocompetent mouse strain and progresses to cancer

Cladel, N. M., Budgeon, L. R., Balogh, K. K., Cooper, T. K., Brendle, S. A., Christensen, N. D., Schell, T. D. & Hu, J., Dec 1 2017, In : Scientific reports. 7, 1, 16932.

Research output: Contribution to journalArticle

Papillomavirus Infections
Mucous Membrane
Neoplasms
Nude Mice
Infection
4 Citations (Scopus)

Mouse papillomavirus infections spread to cutaneous sites with progression to malignancy

Cladel, N. M., Budgeon, L. R., Cooper, T. K., Balogh, K. K., Christensen, N. D., Myers, R., Majerciak, V., Gotte, D., Zheng, Z. M. & Hu, J., Oct 2017, In : Journal of General Virology. 98, 10, p. 2520-2529 10 p., 000926.

Research output: Contribution to journalArticle

Papillomavirus Infections
Skin
Neoplasms
Viral DNA
Infection
2 Citations (Scopus)

MTI-101 treatment inducing activation of Stim1 and TRPC1 expression is a determinant of response in multiple myeloma

Emmons, M. F., Anreddy, N., Cuevas, J., Steinberger, K., Yang, S., McLaughlin, M., Silva, A. & Hazlehurst, L. A., Dec 1 2017, In : Scientific reports. 7, 1, 2685.

Research output: Contribution to journalArticle

Multiple Myeloma
Cell Death
Cell Line
Therapeutics
Peptidomimetics
1 Citation (Scopus)
Sulfolobus solfataricus
DNA Polymerase beta
Deoxyguanosine
Benzo(a)pyrene
DNA-Directed DNA Polymerase
4 Citations (Scopus)

Mutagen resistance and mutation restriction of St. Louis encephalitis virus

Griesemer, S. B., Kramer, L. D., van Slyke, G. A., Pata, J. D., Gohara, D. W., Cameron, C. E. & Ciota, A. T., Feb 1 2017, In : Journal of General Virology. 98, 2, p. 201-211 11 p., 000682.

Research output: Contribution to journalArticle

St. Louis Encephalitis Viruses
RNA Replicase
Mutagens
Mutation
Culicidae
1 Citation (Scopus)

Mutations in HPV18 E1ˆE4 impact virus capsid assembly, infectivity competence, and maturation

Biryukov, J., Myers, J. C., McLaughlin-Drubin, M. E., Griffin, H. M., Milici, J., Doorbar, J. & Meyers, C., Dec 19 2017, In : Viruses. 9, 12, 385.

Research output: Contribution to journalArticle

Virus Assembly
Capsid
Mental Competency
Viruses
Mutation
3 Citations (Scopus)

N2-Substituted 2′-Deoxyguanosine Triphosphate Derivatives as Selective Substrates for Human DNA Polymerase κ

Gowda, A. S. P., Lee, M. & Spratt, T., Jan 1 2017, In : Angewandte Chemie - International Edition. 56, 10, p. 2628-2631 4 p.

Research output: Contribution to journalArticle

DNA-Directed DNA Polymerase
DNA
Derivatives
Substrates
Azides
2 Citations (Scopus)

Nanoparticle-Programmed Surface for Drug Release and Cell Regulation via Reversible Hybridization Reaction

Jiang, P., Li, S., Lai, J., Zheng, H., Lin, C., Shi, P. & Wang, Y., Feb 8 2017, In : ACS Applied Materials and Interfaces. 9, 5, p. 4467-4474 8 p.

Research output: Contribution to journalArticle

Nanoparticles
Pharmaceutical Preparations
Stents
Oligonucleotides
Drug delivery

NOD2 genetic variants predispose one of two familial adenomatous polyposis siblings to pouchitis through microbiome dysbiosis

Schieffer, K. M., Wright, J. R., Harris, L. R., Deiling, S., Yang, Z., Lamendellab, R., Yochum, G. & Koltun, W., Nov 1 2017, In : Journal of Crohn's and Colitis. 11, 11, p. 1393-1397 5 p.

Research output: Contribution to journalArticle

Dysbiosis
Pouchitis
Adenomatous Polyposis Coli
Microbiota
Siblings
2 Citations (Scopus)

Novel chemical scaffolds for inhibition of rifamycin-resistant RNA polymerase discovered from high-throughput screening

Scharf, N. T., Molodtsov, V., Kontos, A., Murakami, K. S. & Garcia, G. A., Jan 1 2017, In : SLAS Discovery. 22, 3, p. 287-297 11 p.

Research output: Contribution to journalArticle

DNA-Directed RNA Polymerases
Scaffolds
Screening
Mycobacterium tuberculosis
Throughput
10 Citations (Scopus)

Orthogonal Comparison of GC-MS and 1H NMR Spectroscopy for Short Chain Fatty Acid Quantitation

Cai, J., Zhang, J., Tian, Y., Zhang, L., Hatzakis, E., Krausz, K. W., Smith, P. B., Gonzalez, F. J. & Patterson, A. D., Aug 1 2017, In : Analytical Chemistry. 89, 15, p. 7900-7906 7 p.

Research output: Contribution to journalArticle

Volatile Fatty Acids
Gas chromatography
Nuclear magnetic resonance spectroscopy
Mass spectrometry
Butyric Acid
6 Citations (Scopus)

p120-catenin downregulation and PIK3CA mutations cooperate to induce invasion through MMP1 in HNSCC

Kidacki, M., Lehman, H. L., Green, M. V., Warrick, J. & Stairs, D., Oct 1 2017, In : Molecular Cancer Research. 15, 10, p. 1398-1409 12 p.

Research output: Contribution to journalArticle

Down-Regulation
Mutation
Phosphatidylinositol 3-Kinases
Neoplasm Metastasis
Neoplasms