Research Output 1963 2019

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23 Citations (Scopus)

Apoptotic mechanisms during competition of ribosomal protein mutant cells: Roles of the initiator caspases Dronc and Dream/Strica

Kale, A., Li, W., Lee, C. H. & Baker, N. E., Aug 7 2015, In : Cell Death and Differentiation. 22, 8, p. 1300-1312 13 p.

Research output: Contribution to journalArticle

Initiator Caspases
Ribosomal Proteins
Apoptosis
Baculoviridae
Cell Death
4 Citations (Scopus)

A population-based study of the prevalence of HPV in three districts of Tamil Nadu, India

Sureshkumar, B. T., Santhanam, S., Das, B. C. & Natarajaseenivasan, K., Apr 1 2015, In : International Journal of Gynecology and Obstetrics. 129, 1, p. 58-61 4 p.

Research output: Contribution to journalArticle

India
Cross-Sectional Studies
Population
Infection
International Normalized Ratio
16 Citations (Scopus)

A potential role for gap junctions in breast cancer metastasis to bone

Donahue, H. J., Saunders, M. M., Li, Z., Mastro, A. M., Gay, C. V. & Welch, D. R., Jun 1 2003, In : Journal of Musculoskeletal Neuronal Interactions. 3, 2, p. 156-161 6 p.

Research output: Contribution to journalArticle

Gap Junctions
Breast Neoplasms
Neoplasm Metastasis
Bone and Bones
Connexins
21 Citations (Scopus)

Application of NMR to studies of intrinsically disordered proteins

Gibbs, E. B., Cook, E. C. & Showalter, S. A., Aug 15 2017, In : Archives of Biochemistry and Biophysics. 628, p. 57-70 14 p.

Research output: Contribution to journalArticle

Intrinsically Disordered Proteins
Nuclear magnetic resonance
Nuclear magnetic resonance spectroscopy
Magnetic Resonance Spectroscopy
Proteins
5 Citations (Scopus)

Application of pan-sharpening to SIMS imaging

Tarolli, J., Tian, H. & Winograd, N., Nov 1 2014, In : Surface and Interface Analysis. 46, S1, p. 217-220 4 p.

Research output: Contribution to journalArticle

Secondary ion mass spectrometry
secondary ion mass spectrometry
Imaging techniques
Image fusion
Image resolution
23 Citations (Scopus)

Application of the dual-micropipet technique to the measurement of tumor cell locomotion

You, J., Mastro, A. M. & Dong, C., Apr 10 1999, In : Experimental Cell Research. 248, 1, p. 160-171 12 p.

Research output: Contribution to journalArticle

Cell Movement
Pseudopodia
Neoplasms
Melanoma
Pressure
1 Citation (Scopus)

Approaches to the development of assays for interaction of tobacco-specific nitrosamines with haemoglobin and DNA.

Hecht, S. S., Carmella, S. G., Trushin, N., Spratt, T., Foiles, P. G. & Hoffmann, D., Dec 1 1988, In : IARC scientific publications. 89, p. 121-128 8 p.

Research output: Contribution to journalArticle

Nitrosamines
Tobacco
Hemoglobins
N'-nitrosonornicotine
DNA
2 Citations (Scopus)

A precisely substituted benzopyran targets androgen refractory prostate cancer cells through selective modulation of estrogen receptors

Kumar, R., Verma, V., Sharma, V., Jain, A., Singh, V., Sarswat, A., Maikhuri, J. P., Sharma, V. L. & Gupta, G., Mar 5 2015, In : Toxicology and Applied Pharmacology. 283, 3, p. 187-197 11 p.

Research output: Contribution to journalArticle

Benzopyrans
Estrogen Receptors
Refractory materials
Androgens
Prostatic Neoplasms

A preliminary study on the inhibitory action of target-primaqine on the exoerythrocytic forms of Plasmodium yoelii yoelii

Song, J., Wang, X., Huang, F., Feng, C., Zhang, Z., Huo, Y. & Pang, Q., Jan 1 1995, In : Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases. 13, 2, p. 117-119 3 p.

Research output: Contribution to journalArticle

Plasmodium yoelii
Primaquine
Sporozoites
Parasitemia
Wistar Rats
16 Citations (Scopus)

A primer for carbon-detected NMR applications to intrinsically disordered proteins in solution

Bastidas, M., Gibbs, E. B., Sahu, D. & Showalter, S. A., Jan 1 2015, In : Concepts in Magnetic Resonance Part A: Bridging Education and Research. 44, 1, p. 54-66 13 p.

Research output: Contribution to journalArticle

Intrinsically Disordered Proteins
Carbon
Nuclear magnetic resonance
Experiments
Biomolecules
6 Citations (Scopus)

A Protease Inhibitor Specifically Inhibits Growth of HPV-Infected Keratinocytes

Drubin, D. A., McLaughlin-Drubin, M. E., Clawson, G. & Meyers, C., Jun 1 2006, In : Molecular Therapy. 13, 6, p. 1142-1148 7 p.

Research output: Contribution to journalArticle

Protease Inhibitors
Keratinocytes
Chymases
Growth
Uterine Cervical Dysplasia
171 Citations (Scopus)

A protective and broadly cross-neutralizing epitope of human papillomavirus L2

Gambhira, R., Karanam, B., Jagu, S., Roberts, J. N., Buck, C. B., Bossis, I., Alphs, H., Culp, T., Christensen, N. D. & Roden, R. B. S., Dec 1 2007, In : Journal of virology. 81, 24, p. 13927-13931 5 p.

Research output: Contribution to journalArticle

Human papillomavirus 16
Papillomaviridae
neutralization
epitopes
Epitopes
14 Citations (Scopus)

A quantitative comparison of dibenzo[a,l]pyrene-DNA adduct formation by recombinant human cytochrome P450 microsomes

King, L. C., Adams, L., Allison, J., Kohan, M. J., Nelson, G., Desai, D., Amin, S. & Ross, J. A., Oct 23 1999, In : Molecular Carcinogenesis. 26, 2, p. 74-82 9 p.

Research output: Contribution to journalArticle

DNA Adducts
Microsomes
Cytochrome P-450 Enzyme System
Environmental Carcinogens
Epoxide Hydrolases
1 Citation (Scopus)

A random subset implementation of weighted quantile sum (WQSRS) regression for analysis of high-dimensional mixtures

Curtin, P., Kellogg, J., Cech, N. & Gennings, C., Jan 1 2019, (Accepted/In press) In : Communications in Statistics: Simulation and Computation.

Research output: Contribution to journalArticle

Quantile
High-dimensional
Regression
Subset
Specificity
28 Citations (Scopus)

A range of catalytic efficiencies with avian retroviral protease subunits genetically linked to form single polypeptide chains

Bizub, D., Weber, I. T., Cameron, C. E., Leis, J. P. & Skalka, A. M., Mar 15 1991, In : Journal of Biological Chemistry. 266, 8, p. 4951-4958 8 p.

Research output: Contribution to journalArticle

Peptide Hydrolases
Dimers
Peptides
Substrates
Enzymes
51 Citations (Scopus)

A rapid screen of active site mutants in glycinamide ribonucleotide transformylase

Warren, M. S., Marolewski, A. E. & Benkovic, S., Aug 2 1996, In : Biochemistry. 35, 27, p. 8855-8862 8 p.

Research output: Contribution to journalArticle

Phosphoribosylglycinamide Formyltransferase
Catalyst activity
Catalytic Domain
Mutagenesis
Proton transfer
33 Citations (Scopus)

Archaeal RNA polymerase and transcription regulation

Jun, S. H., Reichlen, M. J., Tajiri, M. & Murakami, K., Feb 1 2011, In : Critical Reviews in Biochemistry and Molecular Biology. 46, 1, p. 27-40 14 p.

Research output: Contribution to journalArticle

Archaeal RNA
DNA-Directed RNA Polymerases
Transcription
Archaea
Archaeal Genome
36 Citations (Scopus)

Archaeal RNA polymerase subunits e and F are not required for transcription in vitro, but a thermococcus kodakarensis mutant lacking subunit F is temperature-sensitive

Hirata, A., Kanai, T., Santangelo, T. J., Tajiri, M., Manabe, K., Reeve, J. N., Imanaka, T. & Murakami, K., Nov 1 2008, In : Molecular Microbiology. 70, 3, p. 623-633 11 p.

Research output: Contribution to journalArticle

Archaeal RNA
Thermococcus
DNA-Directed RNA Polymerases
Temperature
Archaeal Genome
27 Citations (Scopus)

Architecture of the bacteriophage T4 primosome: Electron microscopy studies of helicase (gp41) and primase (gp61)

Norcum, M. T., Warrington, J. A., Spiering, M. M., Ishmael, F., Trakselis, M. A. & Benkovic, S., Mar 8 2005, In : Proceedings of the National Academy of Sciences of the United States of America. 102, 10, p. 3623-3626 4 p.

Research output: Contribution to journalArticle

DNA Primase
Bacteriophage T4
Electron Microscopy
DNA Helicases
Electrons
2 Citations (Scopus)

A re-examination of the metal requirement of Chromobacterium violaceum phenylalanine hydroxylase

Carr, R. T. & Benkovic, S., 1993, In : Advances in Experimental Medicine and Biology. 338, p. 63-66 4 p.

Research output: Contribution to journalArticle

Chromobacterium
Phenylalanine Hydroxylase
Molecular Cloning
Recombinant Proteins
Escherichia coli
23 Citations (Scopus)

A research agenda for curing chronic hepatitis B virus infection

Alter, H., Block, T., Brown, N., Brownstein, A., Brosgart, C., Chang, K. M., Chen, P. J., Chisari, F. V., Cohen, C., El-Serag, H., Feld, J., Gish, R., Glenn, J., Greten, T., Guo, H., Guo, J. T., Hoshida, Y., Hu, J., Kowdley, K. V., Li, W. & 15 others, Liang, J., Locarnini, S., Lok, A. S., Mason, W., McMahon, B., Mehta, A., Perrillo, R., Revill, P., Rice, C. M., Rinaudo, J. A., Schinazi, R., Seeger, C., Shetty, K., Tavis, J. & Zoulim, F., Mar 2018, In : Hepatology. 67, 3, p. 1127-1131 5 p.

Research output: Contribution to journalArticle

Chronic Hepatitis B
Virus Diseases
Hepatitis B virus
Research
44 Citations (Scopus)

ARID1A-mutated ovarian cancers depend on HDAC6 activity

Bitler, B. G., Wu, S., Park, P. H., Hai, Y., Aird, K., Wang, Y., Zhai, Y., Kossenkov, A. V., Vara-Ailor, A., Rauscher, F. J., Zou, W., Speicher, D. W., Huntsman, D. G., Conejo-Garcia, J. R., Cho, K. R., Christianson, D. W. & Zhang, R., Aug 1 2017, In : Nature Cell Biology. 19, 8, p. 962-973 12 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Neoplasms
Apoptosis
Mutation
Chromatin Assembly and Disassembly
12 Citations (Scopus)

A Role for MYC in Lithium-Stimulated Repair of the Colonic Epithelium After DSS-Induced Damage in Mice

Raup-Konsavage, W. M., Cooper, T. & Yochum, G., Feb 1 2016, In : Digestive Diseases and Sciences. 61, 2, p. 410-422 13 p.

Research output: Contribution to journalArticle

Dextran Sulfate
Lithium
Regeneration
Colitis
Epithelium
61 Citations (Scopus)

A role for TBP dimerization in preventing unregulated gene expression

Jackson-Fisher, A. J., Chitikila, C., Mitra, M. & Pugh, B. F., Jan 1 1999, In : Molecular cell. 3, 6, p. 717-727 11 p.

Research output: Contribution to journalArticle

Protein Multimerization
TATA-Box Binding Protein
Gene Expression
Dimerization
Point Mutation
21 Citations (Scopus)
Chromosomes
Aberrations
Chromosome Aberrations
Carcinogens
Lung
15 Citations (Scopus)

Arrest of human mitochondrial RNA polymerase transcription by the biological aldehyde adduct of DNA, M 1dG

Cline, S. D., Lodeiro, M. F., Marnett, L. J., Cameron, C. E. & Arnold, J. J., Nov 1 2010, In : Nucleic acids research. 38, 21, p. 7546-7557 12 p.

Research output: Contribution to journalArticle

DNA Adducts
DNA-Directed RNA Polymerases
DNA Repair
Mitochondrial Genes
Single-Stranded DNA
9 Citations (Scopus)

Arsenic trioxide plus PX-478 achieves effective treatment in pancreatic ductal adenocarcinoma

Lang, M., Wang, X., Wang, H., Dong, J., Lan, C., Hao, J., Huang, C., Li, X., Yu, M., Yang, Y., Yang, S. & Ren, H., Aug 10 2016, In : Cancer Letters. 378, 2, p. 87-96 10 p.

Research output: Contribution to journalArticle

Adenocarcinoma
Hypoxia-Inducible Factor 1
Reactive Oxygen Species
Pancreatic Neoplasms
Apoptosis
57 Citations (Scopus)

ARTIST: High-Resolution Genome-Wide Assessment of Fitness Using Transposon-Insertion Sequencing

Pritchard, J. R., Chao, M. C., Abel, S., Davis, B. M., Baranowski, C., Zhang, Y. J., Rubin, E. J. & Waldor, M. K., Nov 1 2014, In : PLoS genetics. 10, 11

Research output: Contribution to journalArticle

transposons
fitness
genome
Genome
Growth
71 Citations (Scopus)

Aryl hydrocarbon (Ah) receptor levels are selectively modulated by hsp90-associated immunophilin homolog XAP2

Meyer, B. K., Petrulis, J. R. & Perdew, G. H., Jan 1 2000, In : Cell Stress and Chaperones. 5, 3, p. 243-254 12 p.

Research output: Contribution to journalArticle

Immunophilins
Aryl Hydrocarbon Receptors
Proteins
Macrocyclic Compounds
Tacrolimus Binding Protein 1A
10 Citations (Scopus)
Aryl Hydrocarbon Receptor Nuclear Translocator
Aryl Hydrocarbon Receptors
Periodicity
Serine
Phosphorylation
55 Citations (Scopus)

Aryl-hydrocarbon receptor activation regulates constitutive androstane receptor levels in murine and human liver

Patel, R. D., Holhngshead, B. D., Omiecinski, C. J. & Perdew, G. H., Jul 1 2007, In : Hepatology. 46, 1, p. 209-218 10 p.

Research output: Contribution to journalArticle

Aryl Hydrocarbon Receptors
Liver
Messenger RNA
constitutive androstane receptor
Genes
16 Citations (Scopus)

Aryl hydrocarbon receptor activation synergistically induces lipopolysaccharide-mediated expression of proinflammatory chemokine (c-c motif) ligand 20

Lahoti, T. S., Boyer, J. A., Kusnadi, A., Muku, G. E., Murray, I. A. & Perdew, G. H., Nov 1 2015, In : Toxicological Sciences. 148, 1, p. 229-240 12 p., kfv178.

Research output: Contribution to journalArticle

Aryl Hydrocarbon Receptors
Chemokines
Lipopolysaccharides
Macrophages
Chemical activation
28 Citations (Scopus)
Aryl Hydrocarbon Receptors
Rheumatoid Arthritis
Intercellular Signaling Peptides and Proteins
Fibroblasts
Cytokines
24 Citations (Scopus)

Aryl hydrocarbon receptor antagonism mitigates cytokine-mediated inflammatory signalling in primary human fibroblast-like synoviocytes

Lahoti, T. S., John, K., Hughes, J. M., Kusnadi, A., Murray, I. A., Krishnegowda, G., Amin, S. & Perdew, G. H., Oct 1 2013, In : Annals of the Rheumatic Diseases. 72, 10, p. 1708-1716 9 p.

Research output: Contribution to journalArticle

Aryl Hydrocarbon Receptors
Fibroblasts
Cytokines
Rheumatoid Arthritis
Interleukin-6
571 Citations (Scopus)

Aryl hydrocarbon receptor antagonists promote the expansion of human hematopoietic stem cells

Boitano, A. E., Wang, J., Romeo, R., Bouchez, L. C., Parker, A. E., Sutton, S. E., Walker, J. R., Flaveny, C. A., Perdew, G. H., Denison, M. S., Schultz, P. G. & Cooke, M. P., Sep 10 2010, In : Science. 329, 5997, p. 1345-1348 4 p.

Research output: Contribution to journalArticle

Aryl Hydrocarbon Receptors
Hematopoietic Stem Cells
Cell- and Tissue-Based Therapy
Transplants
StemRegenin 1
7 Citations (Scopus)

Aryl hydrocarbon receptor interacting protein targets IRF7 to suppress antiviral signaling and the induction of type I interferon

Zhou, Q., Lavorgna, A., Bowman, M., Hiscott, J. & Harhaj, E. W., Jun 5 2015, In : Journal of Biological Chemistry. 290, 23, p. 14729-14739 11 p.

Research output: Contribution to journalArticle

Interferon Regulatory Factor-7
Interferon Type I
Antiviral Agents
Virus Diseases
Viruses
43 Citations (Scopus)

Aryl hydrocarbon receptor regulates the cholesterol biosynthetic pathway in a dioxin response element-independent manner

Tanos, R., Patel, R. D., Murray, I. A., Smith, P. B., Patterson, A. D. & Perdew, G. H., Jun 1 2012, In : Hepatology. 55, 6, p. 1994-2004 11 p.

Research output: Contribution to journalArticle

Aryl Hydrocarbon Receptors
Dioxins
Biosynthetic Pathways
Response Elements
Cholesterol

A sacrificial process for fabrication of biodegradable polymer membranes with submicron thickness

Beardslee, L. A., Stolwijk, J., Khaladj, D. A., Trebak, M., Halman, J., Torrejon, K. Y., Niamsiri, N. & Bergkvist, M., Aug 1 2016, In : Journal of Biomedical Materials Research - Part B Applied Biomaterials. 104, 6, p. 1192-1201 10 p.

Research output: Contribution to journalArticle

Biodegradable polymers
Membranes
Fabrication
Polycaprolactone
Polymers
5 Citations (Scopus)

A Selective and Cell-Permeable Mitochondrial Calcium Uniporter (MCU) Inhibitor Preserves Mitochondrial Bioenergetics after Hypoxia/Reoxygenation Injury

Woods, J. J., Nemani, N., Shanmughapriya, S., Kumar, A., Zhang, M., Nathan, S. R., Thomas, M., Carvalho, E., Ramachandran, K., Srikantan, S., Stathopulos, P. B., Wilson, J. J. & Madesh, M., Jan 23 2019, In : ACS Central Science. 5, 1, p. 153-166 14 p.

Research output: Contribution to journalArticle

Open Access
Calcium
Signal transduction
Mutagenesis
Ruthenium
Poisons
2 Citations (Scopus)

A selective delta opioid receptor antagonist based on a stilbene core

Hartung, A. M., Navarro, H. A., Wiemer, D. F. & Neighbors, J., Dec 1 2015, In : Bioorganic and Medicinal Chemistry Letters. 25, 23, p. 5532-5535 4 p.

Research output: Contribution to journalArticle

naltrindole
Stilbenes
delta Opioid Receptor
Narcotic Antagonists
Conformations
6 Citations (Scopus)

A selenium containing inhibitor for the treatment of hepatocellular cancer

Tagaram, H. R. S., Desai, D., Li, G., Liu, D., Rountree, C. B., Gowda, K., Berg, A., Amin, S., Staveley-O’carroll, K. F. & Kimchi, E. T., Mar 24 2016, In : Pharmaceuticals. 9, 2, 18.

Research output: Contribution to journalArticle

Liver Neoplasms
Selenium
Hepatocellular Carcinoma
Phosphatidylinositol 3-Kinases
Neoplasms
9 Citations (Scopus)

A sensitive, radiometric assay for lysophosphatidylcholine

Dobmeyer, D. J., Corr, P. B. & Creer, M. H., Feb 15 1990, In : Analytical Biochemistry. 185, 1, p. 36-43 8 p.

Research output: Contribution to journalArticle

Lysophosphatidylcholines
Lysophospholipids
Choline
Assays
Phospholipids
8 Citations (Scopus)

A sensitive method for the quantification of the mass of inositol phosphates using gas chromatography-mass spectrometry

DaTorre, S. D., Corr, P. B. & Creer, M., Jan 1 1990, In : Journal of Lipid Research. 31, 10, p. 1925-1934 10 p.

Research output: Contribution to journalArticle

Inositol Phosphates
Inositol
Gas chromatography
Gas Chromatography-Mass Spectrometry
Mass spectrometry
117 Citations (Scopus)

A shed NKG2D ligand that promotes natural killer cell activation and tumor rejection

Deng, W., Gowen, B. G., Zhang, L., Wang, L., Lau, S., Iannello, A., Xu, J., Rovis, T. L., Xiong, N. & Raulet, D. H., Apr 3 2015, In : Science. 348, 6230, p. 136-139 4 p.

Research output: Contribution to journalArticle

Natural Killer Cells
Ligands
Immunologic Monitoring
Neoplasms
NK Cell Lectin-Like Receptor Subfamily K
20 Citations (Scopus)

A single coxsackievirus B2 capsid residue controls cytolysis and apoptosis in rhabdomyosarcoma cells

Gullberg, M., Tolf, C., Jonsson, N., Polacek, C., Precechtelova, J., Badurova, M., Sojka, M., Mohlin, C., Israelsson, S., Johansson, K., Bopegamage, S., Hafenstein, S. & Lindberg, A. M., Jun 1 2010, In : Journal of virology. 84, 12, p. 5868-5879 12 p.

Research output: Contribution to journalArticle

cytolysis
Enterovirus
capsid
Rhabdomyosarcoma
Capsid
3 Citations (Scopus)

A single mechanosensitive channel protects Francisella tularensis subsp. holarctica from hypoosmotic shock and promotes survival in the aquatic environment

Williamson, D. R., Dewan, K. K., Patel, T., Wastella, C. M., Ning, G. & Kirimanjeswara, G. S., Mar 1 2018, In : Applied and environmental microbiology. 84, 5, e02203-17.

Research output: Contribution to journalArticle

Francisella tularensis subsp. holarctica
Francisella tularensis
Tularemia
aquatic environment
Fresh Water
102 Citations (Scopus)

A small molecule antagonist of the αυβ 3 integrin suppresses MDA-MB-435 skeletal metastasis

Harms, J. F., Welch, D. R., Samant, R. S., Shevde, L. A., Miele, M. E., Babu, G. R., Goldberg, S. F., Gilman, V. R., Sosnowski, D. M., Campo, D. A., Gay, C. V., Budgeon, L. R., Mercer, R., Jewell, J., Mastro, A. M., Donahue, H. J., Erin, N., Debies, M. T., Meehan, W. J., Jones, A. L. & 11 others, Mbalaviele, G., Nickols, A., Christensen, N. D., Melly, R., Beck, L. N., Kent, J., Rader, R. K., Kotyk, J. J., Pagel, M. D., Westlin, W. F. & Griggs, D. W., Aug 9 2004, In : Clinical and Experimental Metastasis. 21, 2, p. 119-128 10 p.

Research output: Contribution to journalArticle

Integrins
Neoplasm Metastasis
Breast Neoplasms
Bone and Bones
Neoplasms
20 Citations (Scopus)

A Small Molecule Inhibitor of Src Family Kinases Promotes Simple Epithelial Differentiation of Human Pluripotent Stem Cells

Lian, X., Selekman, J., Bao, X., Hsiao, C., Zhu, K. & Palecek, S. P., Mar 20 2013, In : PloS one. 8, 3, e60016.

Research output: Contribution to journalArticle

Pluripotent Stem Cells
src-Family Kinases
Stem cells
stem cells
phosphotransferases (kinases)
19 Citations (Scopus)

A smartphone-based chloridometer for point-of-care diagnostics of cystic fibrosis

Zhang, C., Kim, J. P., Creer, M., Yang, J. & Liu, Z., Nov 15 2017, In : Biosensors and Bioelectronics. 97, p. 164-168 5 p.

Research output: Contribution to journalArticle

Point-of-Care Systems
Smartphones
Cystic Fibrosis
Chlorides
Sweat
22 Citations (Scopus)

A solid-phase extraction/high-performance liquid chromatography-based 32P-postlabeling method for detection of cyclic 1,N 2-propanodeoxyguanosine adducts derived from enals

Pan, J., Davis, W., Trushin, N., Amin, S., Nath, R. G., Salem, N. & Chung, F. L., Jan 1 2006, In : Analytical Biochemistry. 348, 1, p. 15-23 9 p.

Research output: Contribution to journalArticle

2-butenal
Solid Phase Extraction
High performance liquid chromatography
Acrolein
High Pressure Liquid Chromatography