Research Output 1963 2020

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1993
19 Citations (Scopus)

Alterations in the Ah Receptor Level after Staurosporine Treatment

Singh, S. S. & Perdew, G. H., Jan 1 1993, In : Archives of Biochemistry and Biophysics. 305, 1, p. 170-175 6 p.

Research output: Contribution to journalArticle

Aryl Hydrocarbon Receptors
Staurosporine
Cytochrome P-450 CYP1A1
Transcription
Genes
22 Citations (Scopus)

An Examination of the Copper Requirement of Phenylalanine Hydroxylase from Chromobacterium violaceum

Carr, R. T. & Benkovic, S., Jan 1 1993, In : Biochemistry. 32, 51, p. 14132-14138 7 p.

Research output: Contribution to journalArticle

Chromobacterium
Phenylalanine Hydroxylase
Copper
Pterins
Enzymes
51 Citations (Scopus)

Antiorthostatic suspension as a model for the effects of spaceflight on the immune system

Chapes, S. K., Mastro, A. M., Sonnenfeld, G. & Berry, W. D., Jan 1 1993, In : Journal of Leukocyte Biology. 54, 3, p. 227-235 9 p.

Research output: Contribution to journalArticle

Space Flight
Immune System
Suspensions
2 Citations (Scopus)

A re-examination of the metal requirement of Chromobacterium violaceum phenylalanine hydroxylase

Carr, R. T. & Benkovic, S., 1993, In : Advances in Experimental Medicine and Biology. 338, p. 63-66 4 p.

Research output: Contribution to journalArticle

Chromobacterium
Phenylalanine Hydroxylase
Molecular Cloning
Recombinant Proteins
Escherichia coli
22 Citations (Scopus)

A study of tobacco carcinogenesis. LI. Relative potencies of tobacco-specific N-nitrosamines as inducers of lung tumours in A J mice

Hoffmann, D., Djordjevic, M. V., Rivenson, A., Zang, E., Desai, D. & Amin, S., Jul 30 1993, In : Cancer Letters. 71, 1-3, p. 25-30 6 p.

Research output: Contribution to journalArticle

Nitrosamines
Tobacco
Carcinogenesis
Lung
Neoplasms
13 Citations (Scopus)

A transcriptional inhibitor induced in human melanoma cells upon ultraviolet irradiation.

Yang, Y. M., Rutberg, S. E., Luo, F. C., Spratt, T., Halaban, R., Ferrone, S. & Ronai, Z., Jan 1 1993, In : Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research. 4, 7, p. 595-602 8 p.

Research output: Contribution to journalArticle

Nuclear Proteins
Melanoma
Melanocytes
Carrier Proteins
Response Elements
143 Citations (Scopus)

c-Myc induces the expression and activity ornithine decarboxylase

Wagner, A. J., Meyers, C., Laimins, L. A. & Hay, N., Nov 1 1993, In : Cell Growth and Differentiation. 4, 11, p. 879-884 6 p.

Research output: Contribution to journalArticle

Inbred BALB C Mouse
Proto-Oncogene Proteins c-myc
Nucleic Acid Hybridization
RNA Probes
3T3 Cells
42 Citations (Scopus)

Comparison of the substrate-binding pockets of the Rous sarcoma virus and human immunodeficiency virus type 1 proteases

Cameron, C. E., Grinde, B., Jacques, P., Jentoft, J., Leis, J., Wlodawer, A. & Weber, I. T., Jan 1 1993, In : Journal of Biological Chemistry. 268, 16, p. 11711-11720 10 p.

Research output: Contribution to journalArticle

Rous sarcoma virus
Avian Myeloblastosis Virus
Viruses
HIV-1
Peptide Hydrolases
37 Citations (Scopus)
Chlorodiphenyl (54% Chlorine)
Dimethylnitrosamine
Polychlorinated Biphenyls
Lung
Liver
111 Citations (Scopus)

Critical Aspects of Initiation, Promotion, and Progression in Multistage Epidermal Carcinogenesis

Hennings, H., Glick, A. B., Greenhalgh, D. A., Morgan, D. L., Strickland, J. E., Tennenbaum, T. & Yuspa, S. H., Jan 1993, In : Proceedings of the Society for Experimental Biology and Medicine. 202, 1, p. 1-8 8 p.

Research output: Contribution to journalArticle

Skin
Carcinogenesis
Bearings (structural)
Papilloma
Cell culture
52 Citations (Scopus)

Effect of reaction pH on the fidelity and processivity of exonuclease- deficient Klenow polymerase

Eckert, K. A. & Kunkel, T. A., Jan 1 1993, In : Journal of Biological Chemistry. 268, 18, p. 13462-13471 10 p.

Research output: Contribution to journalArticle

Exonucleases
DNA Polymerase I
DNA
Substitution reactions
Bacteriophages
77 Citations (Scopus)

Effects of isothiocyanates on tumorigenesis by benzo[a]pyrene in murine tumor models

Lin, J. M., Amin, S., Trushin, N. & Hecht, S. S., Nov 1 1993, In : Cancer Letters. 74, 3, p. 151-159 9 p.

Research output: Contribution to journalArticle

Isothiocyanates
Benzo(a)pyrene
Carcinogenesis
Lung
Neoplasms
3 Citations (Scopus)

Effects of labetalol on cocaine pharmacokinetics in neonatal piglets

Scalzo, F., Primozic, S., Burge, L. J., Badger, T. M., Creer, M. H., Nehus, C. & Karba, R., Dec 1 1993, In : Developmental Pharmacology and Therapeutics. 20, 1-2, p. 54-63 10 p.

Research output: Contribution to journalArticle

Labetalol
Cocaine
Pharmacokinetics
Animal Models
Area Under Curve
49 Citations (Scopus)

Fidelity of DNA synthesis catalyzed by human DNA polymerase α and HIV-1 reverse transcriptase: Effect of reaction pH

Eckert, K. A. & Kunkel, T. A., Nov 11 1993, In : Nucleic acids research. 21, 22, p. 5212-5220 9 p.

Research output: Contribution to journalArticle

DNA-Directed DNA Polymerase
DNA
HIV-1
DNA Polymerase I
Mutation
128 Citations (Scopus)

Fvb/n mice: An inbred strain sensitive to the chemical induction of squamous cell carcinomas in the skin

Hennings, H., Glick, A. B., Lowry, D. T., Krsmanovic, L. S., Sly, L. M. & Yuspa, S. H., Nov 1 1993, In : Carcinogenesis. 14, 11, p. 2353-2358 6 p.

Research output: Contribution to journalArticle

Inbred Strains Mice
Squamous Cell Carcinoma
9,10-Dimethyl-1,2-benzanthracene
Tetradecanoylphorbol Acetate
Skin
40 Citations (Scopus)
Aryl Hydrocarbon Receptors
Half-Life
Ligands
Occupations
Cytoplasmic and Nuclear Receptors
115 Citations (Scopus)

Human and rabbit paraoxonases: Purification, cloning, sequencing, mapping and role of polymorphism in organophosphate detoxification

Furlong, C. E., Costa, L. G., Hassett, C., Richter, R. J., Sundstrom, J. A., Adler, D. A., Disteche, C. M., Omiecinski, C. J., Chapline, C., Crabb, J. W. & Humbert, R., Jan 1 1993, In : Chemico-Biological Interactions. 87, 1-3, p. 35-48 14 p.

Research output: Contribution to journalArticle

Aryldialkylphosphatase
Detoxification
Organophosphates
Cloning
Polymorphism
80 Citations (Scopus)

Human peripheral lymphocytes as indicators of microsomal epoxide hydrolase activity in liver and lung

Omiecinski, C. J., Aicher, L., Holubkov, R. & Checkoway, H., Jan 1 1993, In : Pharmacogenetics. 3, 3, p. 150-158 9 p.

Research output: Contribution to journalArticle

Epoxide Hydrolases
Lymphocytes
Lung
Liver
Styrene
15 Citations (Scopus)

Identification of 4-(Methylnitrosamino)-1-[3-(6-hydroxypyridyl)]-1-butanone as a Urinary Metabolite of 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone in Rodents

Desai, D., Kagan, S. S., Amin, S., Carmella, S. G. & Hecht, S. S., Nov 1 1993, In : Chemical research in toxicology. 6, 6, p. 794-799 6 p.

Research output: Contribution to journalArticle

Butanones
Metabolites
Rodentia
Nitrosamines
Glucuronides
44 Citations (Scopus)

Immune changes in test animals during spaceflight

Lesnyak, A. T., Sonnenfeld, G., Rykova, M. P., Meshkov, D. O., Mastro, A. & Konstantinova, I., Jan 1 1993, In : Journal of Leukocyte Biology. 54, 3, p. 214-226 13 p.

Research output: Contribution to journalArticle

Space Flight
Astronauts
Colony-Stimulating Factors
Lymphocyte Activation
Natural Killer Cells

Induction of interleukin‐2 receptor α‐chain gene expression by cytochalasin B and 12‐O‐tetradecanoylphorbol‐13‐acetate in T lymphocytes

Gunes, H. & Mastro, A. M., Jan 1 1993, In : Cell Proliferation. 26, 3, p. 281-290 10 p.

Research output: Contribution to journalArticle

Cytochalasin B
T-Lymphocytes
Gene Expression
Messenger RNA
T-Lymphocyte Subsets
30 Citations (Scopus)

Induction of Mammary Cancer by 6-Nitrochrysene in Female CD Rats

El-Bayoumy, K., Rivenson, A., Upadhyaya, P., Chae, Y. H. & Hecht, S. S., Aug 1993, In : Cancer Research. 53, 16, p. 3719-3722 4 p.

Research output: Contribution to journalArticle

Breast Neoplasms
Human Mammary Glands
Dimethyl Sulfoxide
Breast
Vehicle Emissions
129 Citations (Scopus)

Influence of Extracellular Matrix Overlay on Phenobarbital-Mediated Induction of CYP2B1, 2B2, and 3A1 Genes in Primary Adult Rat Hepatocyte Culture

Sidhu, J. S., Farin, F. M. & Omiecinski, C. J., Jan 1 1993, In : Archives of Biochemistry and Biophysics. 301, 1, p. 103-113 11 p.

Research output: Contribution to journalArticle

Cytochrome P-450 CYP2B1
Phenobarbital
Cell culture
Extracellular Matrix
Rats
8 Citations (Scopus)

Influence of periconceptional zinc deficiency on embryonic plasma membrane function in mice

Peters, J. M., Wiley, L. M., Zidenberg‐Cherr, S. & Keen, C. L., 1993, In : Teratogenesis, Carcinogenesis, and Mutagenesis. 13, 1, p. 15-21 7 p.

Research output: Contribution to journalArticle

Cell membranes
Zinc
Sodium
Cell Membrane
Embryonic Structures
59 Citations (Scopus)
Organoselenium Compounds
Lung
Selenium
Selenium Compounds
Sodium Selenite
61 Citations (Scopus)

Localization and Characterization of the 86- and 84-kDa Heat Shock Proteins in Hepa 1c1c7 Cells

Perdew, G. H., Hord, N., Hollenback, C. E. & Welsh, M. J., Jan 1 1993, In : Experimental Cell Research. 209, 2, p. 350-356 7 p.

Research output: Contribution to journalArticle

Heat-Shock Proteins
Antibodies
Cytosol
Cytoplasm
Anti-Idiotypic Antibodies
187 Citations (Scopus)

Loss of expression of transforming growth factor β in skin and skin tumors is associated with hyperproliferation and a high risk for malignant conversion

Glick, A. B., Kulkarni, A. B., Tennenbaum, T., Hennings, H., Flanders, K. C., O'Reilly, M., Sporn, M. B., Karlsson, S. & Yuspa, S. H., Jan 1 1993, In : Proceedings of the National Academy of Sciences of the United States of America. 90, 13, p. 6076-6080 5 p.

Research output: Contribution to journalArticle

Transforming Growth Factors
Skin
Papilloma
Neoplasms
Epidermis
7 Citations (Scopus)

Modulation of carcinogen-induced polyoma DNA replication by organoselenium and organosulfur chemopreventive agents

Foiles, P. G., Miglietta, L., Dolan, L. R., El-Bayoumy, K. & Ronai, Z., Jan 1 1993, In : International journal of oncology. 2, 3, p. 413-418 6 p.

Research output: Contribution to journalArticle

DNA Replication
Carcinogens
Chloramphenicol
Transferases
DNA Tumor Viruses
15 Citations (Scopus)

Monoclonal antibody neutralization of BPV-1

Christensen, N. & Kreider, J. W., Jan 1 1993, In : Virus Research. 28, 2, p. 195-202 8 p.

Research output: Contribution to journalArticle

Virion
Monoclonal Antibodies
Epitopes
Enzyme-Linked Immunosorbent Assay
Human papillomavirus 11
44 Citations (Scopus)

Opposite Stereoselective Resistance to Digestion by Phosphodiesterases I and II of Benzo[a]pyrene Diol Epoxide-Modified Oligonucleotide Adducts

Mao, B., Li, B., Cosman, M., Geacintov, N. E. & Amin, S., Jan 1 1993, In : Biochemistry. 32, 44, p. 11785-11793 9 p.

Research output: Contribution to journalArticle

spleen exonuclease
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide
Phosphodiesterase I
Benzo(a)pyrene
Epoxy Compounds
85 Citations (Scopus)

Phenobarbital induction and tissue-specific expression of the rat CYP2B2 gene in transgenic mice

Ramsden, R., Sommer, K. M. & Omiecinski, C. J., Jan 1 1993, In : Journal of Biological Chemistry. 268, 29, p. 21722-21726 5 p.

Research output: Contribution to journalArticle

Phenobarbital
Transgenic Mice
Rats
Genes
Tissue
26 Citations (Scopus)

Prolactin receptors are found on heterogeneous subpopulations of rat splenocytes

Viselli, S. M. & Mastro, A. M., Jan 1 1993, In : Endocrinology. 132, 2, p. 571-576 6 p.

Research output: Contribution to journalArticle

Prolactin Receptors
Lymphocytes
Immunocompetence
Differentiation Antigens
Surface Antigens
26 Citations (Scopus)

PyvS: A Dominantly Acting Gene in C3H/BiDa Mice Conferring Susceptibility to Tumor Induction by Polyoma Virus

Lukacher, A., Freund, R., Carroll, J. P., Bronson, R. T. & Benjamin, T. L., Sep 1 1993, In : Virology. 196, 1, p. 241-248 8 p.

Research output: Contribution to journalArticle

Polyomavirus
Inbred C3H Mouse
Genes
Virus Receptors
Dominant Genes
280 Citations (Scopus)

Raf exists in a native heterocomplex with hsp90 and p50 that can be reconstituted in a cell-free system

Stancato, L. F., Chow, Y. H., Hutchison, K. A., Perdew, G. H., Jove, R. & Pratt, W. B., Jan 1 1993, In : Journal of Biological Chemistry. 268, 29, p. 21711-21716 6 p.

Research output: Contribution to journalArticle

Oncogene Protein pp60(v-src)
Cell-Free System
Reticulocytes
Rabbits
Sf9 Cells
97 Citations (Scopus)

Regional distribution and expression modulation of cytochrome P-450 and epoxide hydrolase mRNAs in the rat brain

Schilter, B. & Omiecinski, C. J., 1993, In : Molecular Pharmacology. 44, 5, p. 990-996 7 p.

Research output: Contribution to journalArticle

Epoxide Hydrolases
Cytochrome P-450 Enzyme System
Cytochrome P-450 CYP1A2
Messenger RNA
Cytochrome P-450 CYP1A1
111 Citations (Scopus)

Regiospecific expression of cytochrome p-450s and microsomal epoxide hydrolase in human brain tissue

Farin, F. M. & Omiecinski, C. J., Jan 1 1993, In : Journal of Toxicology and Environmental Health. 40, 2-3, p. 317-335 19 p.

Research output: Contribution to journalArticle

Epoxide Hydrolases
Hydrolases
Cytochromes
Brain
Tissue
47 Citations (Scopus)

Roles of Human Hepatic and Pulmonary Cytochrome P450 Enzymes in the Metabolism of the Environmental Carcinogen 6-Nitrochrysene

Chae, Y. H., Yun, C. H., Guengerich, F. P., Kadlubar, F. F. & El-Bayoumy, K., Jan 1 1993, In : Cancer Research. 53, 9, p. 2028-2034 7 p.

Research output: Contribution to journalArticle

Environmental Carcinogens
Cytochrome P-450 Enzyme System
Lung
Liver
Microsomes
19 Citations (Scopus)

Skin test to assess immunity against cottontail rabbit papillomavirus antigens in rabbits with progressing papillomas or after papilloma regression

Höpfl, R. M., Christensen, N., Angell, M. G. & Kreider, J. W., Jan 1 1993, In : Journal of Investigative Dermatology. 101, 2, p. 227-231 5 p.

Research output: Contribution to journalArticle

Cottontail rabbit papillomavirus
Papilloma
Skin Tests
Immunity
Skin
87 Citations (Scopus)

Solution Conformation of the (+)-trans-anti-[BPh]dA Adduct opposite dT in a DNA Duplex: Intercalation of the Covalently Attached Benzo[c]phenanthrene to the 5′-Side of the Adduct Site without Disruption of the Modified Base Pair

Cosman, M., Fiala, R., Hingerty, B. E., Laryea, A., Lee, H., Harvey, R. G., Amin, S., Geacintov, N. E., Broyde, S. & Patel, D., Jan 1 1993, In : Biochemistry. 32, 46, p. 12488-12497 10 p.

Research output: Contribution to journalArticle

Intercalation
Base Pairing
Conformations
Protons
Polycyclic Aromatic Hydrocarbons
10 Citations (Scopus)
Nitrosamines
DNA Adducts
Aldehydes
Hemoglobins
Alcohols
4 Citations (Scopus)

Synthesis of N-(Purin-8-yl)arylamines

Swenson, D. H., El-Bayoumy, K., Shuie, G. H., Hecht, S. S., Fiala, E., Kadlubar, F. F. & Freeman, J. P., Jan 1 1993, In : Chemical research in toxicology. 6, 4, p. 480-485 6 p.

Research output: Contribution to journalArticle

Dimethylformamide
Thiourea
Derivatives
Carbodiimides
Methylation
11 Citations (Scopus)

The effect of the cytochrome P‐450 system inducers on the development of drosophila melanogaster

Fuchs, S. Y., Spiegelman, V. & Belitsky, G. A., Jan 1 1993, In : Journal of Biochemical Toxicology. 8, 2, p. 83-88 6 p.

Research output: Contribution to journalArticle

Drosophila melanogaster
Cytochrome P-450 Enzyme System
Larva
Ecdysone
Phenobarbital
8 Citations (Scopus)

The expression of forms of prolactin receptors in splenocytes and thymocytes of neonatal rats: the effect of milk ingestion.

Günes, H., Grove, D. S., Bour, B., Zawilla, S. & Mastro, A. M., Dec 1 1993, In : Endocrine Regulations. 27, 4, p. 193-200 8 p.

Research output: Contribution to journalArticle

Prolactin Receptors
Thymocytes
Prolactin
Milk
Eating
714 Citations (Scopus)

The molecular basis of the human serum paraoxonase activity polymorphism

Humbert, R., Adler, D. A., Disteche, C. M., Hassett, C., Omiecinski, C. J. & Furlong, C. E., Jan 1 1993, In : Nature Genetics. 3, 1, p. 73-76 4 p.

Research output: Contribution to journalArticle

Aryldialkylphosphatase
Paraoxon
Serum
Parathion
Restriction Mapping
115 Citations (Scopus)

The Suprabasal Expression of α6ß4 Integrin Is Associated with a High Risk for Malignant Progression in Mouse Skin Carcinogenesis

Tennenbaum, T., Weiner, A. K., Belanger, A. J., Glick, A. B., Hennings, H. & Yuspa, S. H., Oct 1993, In : Cancer Research. 53, 20, p. 4803-4810 8 p.

Research output: Contribution to journalArticle

Integrins
Carcinogenesis
Skin
Keratin-13
Neoplasms
28 Citations (Scopus)

Tumor-initiating activity on mouse skin of bay region diol-epoxides of 5,6-dimethylchrysene and benzo[c]phenanthrene

Amin, S., Desai, D. & Hecht, S. S., Oct 1 1993, In : Carcinogenesis. 14, 10, p. 2033-2037 5 p.

Research output: Contribution to journalArticle

Epoxy Compounds
Skin
Neoplasms
Hydrocarbons
Carcinogens
3 Citations (Scopus)

Unwinding and Hydrodynamic Flow Linear Dichroism Characteristics of Supercoiled DNA Covalently Modified with Two Isomeric Methylchrysene Diol Epoxides of Different Biological Activities

Balasta, L., Xu, R., Geacintov, N. E., Swenberg, C. E., Amin, S. & Hecht, S. S., Jan 1 1993, In : Chemical Research in Toxicology. 6, 5, p. 616-624 9 p.

Research output: Contribution to journalArticle

Superhelical DNA
Epoxy Compounds
Hydrodynamics
Bioactivity
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide
1992
4 Citations (Scopus)

A Drosophila simulans mutant strain sensitive to benzo[a]pyrene and 2-acetylaminofluorene

Fuchs, S. Y., Safaev, R. D., Khovanova, E. M., Ugnivenko, H. G., Speigelman, V. S., Lytcheva, T. A., Khitrovo, I. A. & Belitsky, G. A., Jul 1992, In : Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 268, 1, p. 155-163 9 p.

Research output: Contribution to journalArticle

2-Acetylaminofluorene
Poisons
Benzo(a)pyrene
Heterozygote
Drosophila
2 Citations (Scopus)

A handy enzyme for transcription

Peliska, J. A. & Benkovic, S., Jan 1 1992, In : Current Biology. 2, 10, p. 521-523 3 p.

Research output: Contribution to journalArticle

Transcription
Enzymes
16 Citations (Scopus)

Analysis of phospholipid metabolism in murine keratinocytes transformed by the v-ras oncogene: Relationship of phosphatidylinositol turnover and cytokine stimulation to the transformed phenotype

Lee, E., Punnonen, K., Cheng, C., Click, A., Dlugosz, A. & Yuspa, S. H., Dec 1 1992, In : Carcinogenesis. 13, 12, p. 2367-2373 7 p.

Research output: Contribution to journalArticle

ras Genes
Phosphatidylinositols
Keratinocytes
Phospholipids
Cytokines