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The human microsomal epoxide hydrolase gene (ephx1): Complete nucleotide sequence and structural characterization

Hassett, C., Robinson, K. B., Beck, N. B. & Omiecinski, C. J., Jan 1 1994, In : Genomics. 23, 2, p. 433-442 10 p.

Research output: Contribution to journalArticle

71 Scopus citations

The human papillomavirus E6 oncoprotein targets USP15 and TRIM25 to suppress RIG-I-mediated innate immune signaling

Chiang, C., Pauli, E. K., Biryukov, J., Feister, K. F., Meng, M., White, E. A., Münger, K., Howley, P. M., Meyers, C. & Gack, M. U., Mar 1 2018, In : Journal of virology. 92, 6, e01737-17.

Research output: Contribution to journalArticle

26 Scopus citations

The human peroxisome proliferator-activated receptor α gene: Identification and functional characterization of two natural allelic variants

Sapone, A., Peters, J. M., Sakai, S., Tomita, S., Papiha, S. S., Dai, R., Friedman, F. K. & Gonzalez, F. J., Jan 1 2000, In : Pharmacogenetics. 10, 4, p. 321-333 13 p.

Research output: Contribution to journalArticle

102 Scopus citations

The human T-cell leukemia virus type 1 tax oncoprotein requires the ubiquitin-conjugating enzyme Ubc13 for NF-κB activation

Shembade, N., Harhaj, N. S., Yamamoto, M., Akira, S. & Harhaj, E. W., Dec 1 2007, In : Journal of virology. 81, 24, p. 13735-13742 8 p.

Research output: Contribution to journalArticle

85 Scopus citations

The Human Transient Receptor Potential Melastatin 2 Ion Channel Modulates ROS Through Nrf2

Bao, L., Festa, F., Freet, C. S., Lee, J. P., Hirschler-Laszkiewicz, I. M., Chen, S. J., Keefer, K. A., Wang, H. G., Patterson, A. D., Cheung, J. Y. & Miller, B. A., Dec 1 2019, In : Scientific reports. 9, 1, 14132.

Research output: Contribution to journalArticle

Open Access

The impact of fish oil on the chemopreventive efficacy of tamoxifen against development of N-Methyl-N-Nitrosourea-Induced rat mammary carcinogenesis

Manni, A., Xu, H., Washington, S., Aliaga, C., Cooper, T., Richie, J. P., Bruggeman, R., Prokopczyk, B., Calcagnotto, A., Trushin, N., Mauger, D., Verderame, M. F. & El-Bayoumy, K., Mar 1 2010, In : Cancer Prevention Research. 3, 3, p. 322-330 9 p.

Research output: Contribution to journalArticle

30 Scopus citations

The impact of the 2008-2009 economic recession on acute myocardial infarction occurrences in various socioeconomic areas of raritan Bay Region, New Jersey

Li, Y., Rukshin, I., Pan, F., Sen, S., Islam, M., Yousif, A. & Rukshin, V., May 2014, In : North American Journal of Medical Sciences. 6, 5, p. 215-218 4 p.

Research output: Contribution to journalArticle

2 Scopus citations

The induction of yes-associated protein expression after arterial injury is crucial for smooth muscle phenotypic modulation and neointima formation

Wang, X., Hu, G., Gao, X., Wang, Y., Zhang, W., Harmon, E. Y., Zhi, X., Xu, Z., Lennartz, M. R., Barroso, M., Trebak, M., Chen, C. & Zhou, J., Nov 1 2012, In : Arteriosclerosis, thrombosis, and vascular biology. 32, 11, p. 2662-2669 8 p.

Research output: Contribution to journalArticle

43 Scopus citations

The influence of methyl substitution on the mutagenicity of nitronaphthalenes and nitrobiphenyls

El-Bayoumy, K., Lavoie, E. J., Hecht, S. S., Fow, E. A. & Hoffmann, D., Apr 1981, In : Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 81, 2, p. 143-153 11 p.

Research output: Contribution to journalArticle

52 Scopus citations

The innate immune adaptor MyD88 is dispensable for spontaneous autoimmune demyelination in a mouse model of multiple sclerosis

Wexler, A. G., Frielle, C., Berry, G., Budgeon, L. R., Baccon, J., Christensen, N. D. & Waldner, H., Feb 15 2013, In : Journal of Neuroimmunology. 255, 1-2, p. 60-69 10 p.

Research output: Contribution to journalArticle

7 Scopus citations

The Integrated Genomic Landscape of Thymic Epithelial Tumors

The Cancer Genome Atlas Network, Feb 12 2018, In : Cancer Cell. 33, 2, p. 244-258.e10

Research output: Contribution to journalArticle

37 Scopus citations

The interaction of [3H]TPA with bovine lymph node lymphocytes in vitro

Mastro, A. M. & Pepin, K. G., Jan 1 1980, In : Chemico-Biological Interactions. 30, 2, p. 171-179 9 p.

Research output: Contribution to journalArticle

7 Scopus citations

The interferon-related developmental regulator 1 is used by human papillomavirus to suppress NFκB activation

Tummers, B., Goedemans, R., Pelascini, L. P. L., Jordanova, E. S., Van Esch, E. M. G., Meyers, C., Melief, C. J. M., Boer, J. M. & Van Der Burg, S. H., 2015, In : Nature communications. 6, 6537.

Research output: Contribution to journalArticle

33 Scopus citations

The in vitro fidelity of yeast DNA polymerase δ and polymerase e{open} holoenzymes during dinucleotide microsatellite DNA synthesis

Abdulovic, A. L., Hile, S. E., Kunkel, T. A. & Eckert, K. A., May 5 2011, In : DNA Repair. 10, 5, p. 497-505 9 p.

Research output: Contribution to journalArticle

20 Scopus citations

The IRAK-ERK-p67phox-Nox-2 axis mediates TLR4, 2-induced ROS production for IL-1β transcription and processing in monocytes

Singh, A., Singh, V., Tiwari, R. L., Chandra, T., Kumar, A., Dikshit, M. & Barthwal, M. K., Nov 1 2016, In : Cellular and Molecular Immunology. 13, 6, p. 747-763 17 p.

Research output: Contribution to journalArticle

23 Scopus citations

The isolation and properties of the dimeric subunit of Concanavalin A

Pazur, J. H., Perloff, M. D., Frymoyer, A. R., Jensen, C. J. P., Micolochick, H. & Mastro, A., Dec 1 2000, In : Journal of Protein Chemistry. 19, 5, p. 353-359 7 p.

Research output: Contribution to journalArticle

2 Scopus citations

The JIL-1 kinase interacts with lamin Dm0 and regulates nuclear lamina morphology of Drosophila nurse cells

Bao, X., Zhang, W., Krencik, R., Deng, H., Wang, Y., Girton, J., Johansen, J. & Johansen, K. M., Nov 1 2005, In : Journal of Cell Science. 118, 21, p. 5079-5087 9 p.

Research output: Contribution to journalArticle

16 Scopus citations

The JIL-1 tandem kinase mediates histone H3 phosphorylation and is required for maintenance of chromatin structure in Drosophila

Wang, Y., Zhang, W., Jin, Y., Johansen, J. & Johansen, K. M., May 18 2001, In : Cell. 105, 4, p. 433-443 11 p.

Research output: Contribution to journalArticle

164 Scopus citations

The joint effect of air pollution exposure and copy number variation on risk for autism

Kim, D., Volk, H., Girirajan, S., Pendergrass, S., Hall, M. A., Verma, S. S., Schmidt, R. J., Hansen, R. L., Ghosh, D., Ludena-Rodriguez, Y., Kim, K., Ritchie, M. D., Hertz-Picciotto, I. & Selleck, S. B., Sep 2017, In : Autism Research. 10, 9, p. 1470-1480 11 p.

Research output: Contribution to journalArticle

13 Scopus citations

The kinase IKKα inhibits activation of the transcription factor NF-κB by phosphorylating the regulatory molecule TAX1BP1

Shembade, N., Pujari, R., Harhaj, N. S., Abbott, D. W. & Harhaj, E. W., Sep 1 2011, In : Nature Immunology. 12, 9, p. 834-843 10 p.

Research output: Contribution to journalArticle

71 Scopus citations

The kinases aurora B and mTOR regulate the G1-S cell cycle progression of T lymphocytes

Song, J., Salek-Ardakani, S., So, T. & Croft, M., Jan 1 2007, In : Nature Immunology. 8, 1, p. 64-73 10 p.

Research output: Contribution to journalArticle

89 Scopus citations

The late region differentially regulates the in Vitro transformation by cottontail rabbit papillomavirus DNA in different cell types

Meyers, C. & Wettstein, F. O., Apr 1991, In : Virology. 181, 2, p. 637-646 10 p.

Research output: Contribution to journalArticle

9 Scopus citations

The linker histone plays a dual role during gametogenesis in saccharomyces cerevisiae

Bryant, J. M., Govin, J., Zhang, L., Donahue, G., Pugh, B. F. & Berger, S. L., Jul 1 2012, In : Molecular and cellular biology. 32, 14, p. 2771-2783 13 p.

Research output: Contribution to journalArticle

14 Scopus citations

The lysosomal TRPML1 channel regulates triple negative breast cancer development by promoting mTORC1 and purinergic signaling pathways

Xu, M., Almasi, S., Yang, Y., Yan, C., Sterea, A. M., Rizvi Syeda, A. K., Shen, B., Richard Derek, C., Huang, P., Gujar, S., Wang, J., Zong, W. X., Trebak, M., El Hiani, Y. & Dong, X. P., May 2019, In : Cell Calcium. 79, p. 80-88 9 p.

Research output: Contribution to journalArticle

9 Scopus citations

The major lipid peroxidation product, trans-4-hydroxy-2-nonenal, preferentially forms DNA adducts at codon 249 of human p53 gene, a unique mutational hotspot in hepatocellular carcinoma

Hu, W., Feng, Z., Eveleigh, J., Iyer, G., Pan, J., Amin, S., Chung, F. L. & Tang, M. S., Nov 1 2002, In : Carcinogenesis. 23, 11, p. 1781-1789 9 p.

Research output: Contribution to journalArticle

193 Scopus citations

The mammalian TRPC cation channels

Vazquez, G., Wedel, B. J., Aziz, O., Trebak, M. & Putney, J. W., Dec 6 2004, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1742, 1-3, p. 21-36 16 p.

Research output: Contribution to journalArticle

243 Scopus citations

The mechanism of phenylalanine hydroxylase.

Lazarus, R. A., Wallick, D. E., Dietrich, R. F., Gottschall, D. W., Benkovic, S., Gaffney, B. J. & Shiman, R., Jul 1 1982, In : Federation Proceedings. 41, 9, p. 2605-2607 3 p.

Research output: Contribution to journalArticle

10 Scopus citations

The mechanism of sphingosine enhancement of phorbol ester-mediated Phospholipase D activation in lymphocytes

Cao, Y. Z., Mastro, A. M., Eskew, M. L., Hildenbrandt, G., Reddy, P. V. & Reddy, C. C., Dec 26 1995, In : Biochemical and Biophysical Research Communications. 217, 3, p. 908-915 8 p.

Research output: Contribution to journalArticle

4 Scopus citations

The Microbial Ecosystem Distinguishes Chronically Diseased Tissue from Adjacent Tissue in the Sigmoid Colon of Chronic, Recurrent Diverticulitis Patients

Schieffer, K. M., Sabey, K., Wright, J. R., Toole, D. R., Drucker, R., Tokarev, V., Harris, L. R., Deiling, S., Eshelman, M. A., Hegarty, J. P., Yochum, G. S., Koltun, W. A., Lamendella, R. & Stewart, D. B., Dec 1 2017, In : Scientific reports. 7, 1, 8467.

Research output: Contribution to journalArticle

11 Scopus citations

The microbiome modulating activity of bile acids

Tian, Y., Gui, W., Koo, I., Smith, P. B., Allman, E. L., Nichols, R. G., Rimal, B., Cai, J., Liu, Q. & Patterson, A. D., Jan 1 2020, (Accepted/In press) In : Gut microbes.

Research output: Contribution to journalArticle

The minimum replication origin of Merkel cell polyomavirus has a unique large T-antigen loading architecture and requires small T-antigen expression for optimal replication

Kwun, H. J., Guastafierro, A., Shuda, M., Meinke, G., Bohm, A., Moore, P. S. & Chang, Y., Dec 1 2009, In : Journal of virology. 83, 23, p. 12118-12128 11 p.

Research output: Contribution to journalArticle

80 Scopus citations

The Mitochondrial Calcium Uniporter Matches Energetic Supply with Cardiac Workload during Stress and Modulates Permeability Transition

Luongo, T. S., Lambert, J. P., Yuan, A., Zhang, X., Gross, P., Song, J., Shanmughapriya, S., Gao, E., Jain, M., Houser, S. R., Koch, W. J., Cheung, J. Y., Madesh, M. & Elrod, J. W., Jul 7 2015, In : Cell Reports. 12, 1, p. 23-34 12 p.

Research output: Contribution to journalArticle

Open Access
141 Scopus citations

The mitochondrial deoxyguanosine kinase is required for cancer cell stemness in lung adenocarcinoma

Lin, S., Huang, C., Sun, J., Bollt, O., Wang, X., Martine, E., Kang, J., Taylor, M. D., Fang, B., Singh, P. K., Koomen, J., Hao, J. & Yang, S., Dec 1 2019, In : EMBO Molecular Medicine. 11, 12, e10849.

Research output: Contribution to journalArticle

Open Access

The mitochondrial Na+/Ca2+ exchanger is essential for Ca2+ homeostasis and viability

Luongo, T. S., Lambert, J. P., Gross, P., Nwokedi, M., Lombardi, A. A., Shanmughapriya, S., Carpenter, A. C., Kolmetzky, D., Gao, E., Van Berlo, J. H., Tsai, E. J., Molkentin, J. D., Chen, X., Madesh, M., Houser, S. R. & Elrod, J. W., May 4 2017, In : Nature. 545, 7652, p. 93-97 5 p.

Research output: Contribution to journalArticle

81 Scopus citations
20 Scopus citations

The molecular basis of the human serum paraoxonase activity polymorphism

Humbert, R., Adler, D. A., Disteche, C. M., Hassett, C., Omiecinski, C. J. & Furlong, C. E., Jan 1 1993, In : Nature Genetics. 3, 1, p. 73-76 4 p.

Research output: Contribution to journalArticle

721 Scopus citations

The mouse and human Ah receptor differ in recognition of LXXLL motifs

Flaveny, C., Reen, R. K., Kusnadi, A. & Perdew, G. H., Mar 15 2008, In : Archives of Biochemistry and Biophysics. 471, 2, p. 215-223 9 p.

Research output: Contribution to journalArticle

28 Scopus citations

The mouse papillomavirus infection model

Hu, J., Cladel, N. M., Budgeon, L. R., Balogh, K. K. & Christensen, N. D., Sep 2017, In : Viruses. 9, 9, 246.

Research output: Contribution to journalArticle

9 Scopus citations

The multiple roles of the unfolded protein response regulator IRE1α in cancer

Chalmers, F., Mogre, S., Son, J., Blazanin, N. & Glick, A. B., Jan 1 2019, In : Molecular Carcinogenesis. 58, 9, p. 1623-1630 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

The mutator form of polymerase β with amino acid substitution at tyrosine 265 in the hinge region displays an increase in both base substitution and frame shift errors

Opresko, P. L., Sweasy, J. B. & Eckert, K., Feb 24 1998, In : Biochemistry. 37, 8, p. 2111-2119 9 p.

Research output: Contribution to journalArticle

56 Scopus citations

The Myc 3'wnt-responsive element regulates homeostasis and regeneration in the mouse intestinal tract

Konsavage, W. M., Jin, G. & Yochum, G. S., Oct 1 2012, In : Molecular and cellular biology. 32, 19, p. 3891-3902 12 p.

Research output: Contribution to journalArticle

16 Scopus citations

The Myc 3' Wnt-responsive element suppresses colonic tumorigenesis

Konsavage, W. M. & Yochum, G. S., May 2014, In : Molecular and cellular biology. 34, 9, p. 1659-1669 11 p.

Research output: Contribution to journalArticle

8 Scopus citations

The MYC 3′ Wnt-responsive element drives oncogenic MYC expression in human colorectal cancer cells

Rennoll, S. A., Eshelman, M. A., Raup-Konsavage, W. M., Kawasawa, Y. I. & Yochum, G. S., May 23 2016, In : Cancers. 8, 5, 52.

Research output: Contribution to journalArticle

11 Scopus citations

The Myc 3′ Wnt responsive element regulates neutrophil recruitment after acute colonic injury in mice

Konsavage, W. M., Roper, J. N., Ishmael, F. T. & Yochum, G. S., Oct 1 2013, In : Digestive Diseases and Sciences. 58, 10, p. 2858-2867 10 p.

Research output: Contribution to journalArticle

5 Scopus citations

The natural history of human papillomavirus type 16 capsid antibodies among a cohort of university women

Carter, J. J., Koutsky, L. A., Wipf, G. C., Christensen, N. D., Lee, S. K., Kuypers, J., Kiviat, N. & Galloway, D. A., Jan 1 1996, In : Journal of Infectious Diseases. 174, 5, p. 927-936 10 p.

Research output: Contribution to journalArticle

260 Scopus citations

The NLRP4-DTX4 axis: A key suppressor of TBK1 and innate antiviral signaling

Charoenthongtrakul, S., Gao, L. & Harhaj, E. W., Nov 1 2012, In : Cellular and Molecular Immunology. 9, 6, p. 431-433 3 p.

Research output: Contribution to journalArticle

3 Scopus citations

The novel asymmetric entry intermediate of a picornavirus captured with nanodiscs

Lee, H., Shingler, K. L., Organtini, L. J., Ashley, R. E., Makhov, A. M., Conway, J. F. & Hafenstein, S., Aug 2016, In : Science Advances. 2, 8, e1501929.

Research output: Contribution to journalArticle

30 Scopus citations

The novel Isatin analog KS99 targets stemness markers in acute myeloid leukemia

Annageldiyev, C., Gowda, K., Patel, T., Bhattacharya, P., Tan, S. F., Iyer, S., Desai, D., Dovat, S., Feith, D. J., Loughran, T. P., Amin, S., Claxton, D. & Sharma, A., Mar 1 2020, In : Haematologica. 105, 3, p. 687-696 10 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

The nuclear export signal of splicing factor Uap56p interacts with nuclear pore-associated protein Rae1p for mRNA export in Schizosaccharomyces pombe

Thakurta, A. G., Selvanathan, S. P., Patterson, A. D., Gopal, G. & Dhar, R., Jun 15 2007, In : Journal of Biological Chemistry. 282, 24, p. 17507-17516 10 p.

Research output: Contribution to journalArticle

9 Scopus citations

The Nuclear Pore-Associated TREX-2 Complex Employs Mediator to Regulate Gene Expression

Schneider, M., Hellerschmied, D., Schubert, T., Amlacher, S., Vinayachandran, V., Reja, R., Pugh, B. F., Clausen, T. & Köhler, A., Aug 27 2015, In : Cell. 162, 5, p. 1016-1028 13 p.

Research output: Contribution to journalArticle

53 Scopus citations