Research Output 1963 2019

Filter
Article
2017
8 Citations (Scopus)

Parvovirus capsid structures required for infection: Mutations controlling receptor recognition and protease cleavages

Callaway, H. M., Feng, K. H., Lee, D. W., Allison, A. B., Pinard, M., McKenna, R., Agbandje-McKenna, M., Hafenstein, S. & Parrish, C. R., Jan 1 2017, In : Journal of virology. 91, 2, e01871-16.

Research output: Contribution to journalArticle

Parvovirus
Protoparvovirus
capsid
Capsid
Peptide Hydrolases
16 Citations (Scopus)

PD-1 blockade promotes epitope spreading in anticancer CD8+ T cell responses by preventing fratricidal death of subdominant clones to relieve immunodomination

Memarnejadian, A., Meilleur, C. E., Shaler, C. R., Khazaie, K., Bennink, J. R., Schell, T. & Haeryfar, S. M. M., Nov 1 2017, In : Journal of Immunology. 199, 9, p. 3348-3359 12 p.

Research output: Contribution to journalArticle

Epitopes
Clone Cells
T-Lymphocytes
Neoplasms
Immunotherapy
4 Citations (Scopus)

Peptide specific monoclonal antibodies of Leptospiral LigA for acute diagnosis of leptospirosis

Kanagavel, M., Santhanam, S., Aishwarya, K. V. L., Ponmurugan, K., Murugan, K., Al-Dhabi, N. A. & Natarajaseenivasan, K., Dec 1 2017, In : Scientific reports. 7, 1, 3250.

Research output: Contribution to journalArticle

Open Access
Leptospirosis
Enzyme-Linked Immunosorbent Assay
Monoclonal Antibodies
Peptides
Urine
2 Citations (Scopus)

Perfluorooctane sulfonate-induced hepatic steatosis in male sprague dawley rats is not attenuated by dietary choline supplementation

Bagley, B. D., Chang, S. C., Ehresman, D. J., Eveland, A., Zitzow, J. D., Parker, G. A., Peters, J. M., Wallace, K. B. & Butenhoff, J. L., Dec 1 2017, In : Toxicological Sciences. 160, 2, p. 284-298 15 p.

Research output: Contribution to journalArticle

Dietary Supplements
Choline
Sprague Dawley Rats
Rats
Liver
8 Citations (Scopus)

Peroxisome proliferator-activated receptor-β/δ inhibits human neuroblastoma cell tumorigenesis by inducing p53- and SOX2-mediated cell differentiation

Yao, P. L., Chen, L., Dobrzański, T. P., Zhu, B., Kang, B. H., Müller, R., Gonzalez, F. J. & Peters, J. M., May 1 2017, In : Molecular Carcinogenesis. 56, 5, p. 1472-1483 12 p.

Research output: Contribution to journalArticle

Peroxisome Proliferator-Activated Receptors
Neuroblastoma
Cell Differentiation
Carcinogenesis
Tretinoin
1 Citation (Scopus)

Peroxisome proliferator-activated receptor-β/δ modulates mast cell phenotype

Yao, P. L., Morales, J. L., Gonzalez, F. J. & Peters, J. M., Apr 1 2017, In : Immunology. 150, 4, p. 456-467 12 p.

Research output: Contribution to journalArticle

Peroxisome Proliferator-Activated Receptors
Mast Cells
Phenotype
Bone and Bones
Cytokines
6 Citations (Scopus)

Phospholipase A2-activating protein is associated with a novel form of leukoencephalopathy

Falik Zaccai, T. C., Savitzki, D., Zivony-Elboum, Y., Vilboux, T., Fitts, E. C., Shoval, Y., Kalfon, L., Samra, N., Keren, Z., Gross, B., Chasnyk, N., Straussberg, R., Mullikin, J. C., Teer, J. K., Geiger, D., Kornitzer, D., Bitterman-Deutsch, O., Samson, A. O., Wakamiya, M., Peterson, J. W. & 7 others, Kirtley, M. L., Pinchuk, I., Baze, W. B., Gahl, W. A., Kleta, R., Anikster, Y. & Chopra, A. K., Jan 1 2017, In : Brain. 140, 2, p. 370-386 17 p.

Research output: Contribution to journalArticle

Open Access
Leukoencephalopathies
Dinoprostone
Cytosolic Phospholipases A2
Fibroblasts
Maintenance
18 Citations (Scopus)

Phosphorylation induces sequence-specific conformational switches in the RNA polymerase II C-terminal domain

Gibbs, E. B., Lu, F., Portz, B., Fisher, M. J., Medellin, B. P., Laremore, T. N., Zhang, Y. J., Gilmour, D. S. & Showalter, S. A., May 12 2017, In : Nature communications. 8, 15233.

Research output: Contribution to journalArticle

RNA Polymerase III
phosphorylation
Phosphorylation
RNA Polymerase II
switches
2 Citations (Scopus)

Pigs, unlike mice, have two distinct colonic stem cell populations similar to humans that respond to high-calorie diet prior to insulin resistance

Charepalli, V., Reddivari, L., Radhakrishnan, S., Eriksson, E., Xiao, X., Kim, S. W., Shen, F., Kumar, M. V., Li, Q., Bhat, V. B., Knight, R. & Vanamala, J. K. P., Aug 1 2017, In : Cancer Prevention Research. 10, 8, p. 442-450 9 p.

Research output: Contribution to journalArticle

Insulin Resistance
Swine
Stem Cells
Diet
Population
2 Citations (Scopus)

PIP-on-a-chip: A Label-free Study of Protein-phosphoinositide Interactions

Shengjuler, D., Sun, S., Cremer, P. S. & Cameron, C. E., Jul 27 2017, In : Journal of visualized experiments : JoVE. 125

Research output: Contribution to journalArticle

Phosphatidylinositols
Labels
Proteins
Membranes
Phospholipase C delta
6 Citations (Scopus)

PLATO software provides analytic framework for investigating complexity beyond genome-wide association studies

Hall, M., Wallace, J., Lucas, A., Kim, D., Basile, A. O., Verma, S. S., McCarty, C. A., Brilliant, M. H., Peissig, P. L., Kitchner, T. E., Verma, A., Pendergrass, S. A., Dudek, S. M., Moore, J. H. & Ritchie, M. D., Dec 1 2017, In : Nature communications. 8, 1, 1167.

Research output: Contribution to journalArticle

genome
Genome-Wide Association Study
Software
Genes
computer programs
9 Citations (Scopus)

Potent inhibition of human cytomegalovirus by modulation of cellular SNARE syntaxin 5

Cruz, L., Streck, N. T., Ferguson, K., Desai, T., Desai, D., Amin, S. & Buchkovich, N., Jan 1 2017, In : Journal of virology. 91, 1, e01637-16.

Research output: Contribution to journalArticle

Human herpesvirus 5
Qa-SNARE Proteins
SNARE Proteins
Virus Assembly
Cytomegalovirus
6 Citations (Scopus)

PPARβ/δ and PPARγ inhibit melanoma tumorigenicity by modulating inflammation and apoptosis

Borland, M. G., Yao, P. L., Kehres, E. M., Lee, C., Pritzlaff, A. M., Ola, E., Wagner, A. L., Shannon, B. E., Albrecht, P. P., Zhu, B., Kang, B. H., Robertson, G., Gonzalez, F. J. & Peters, J. M., Oct 1 2017, In : Toxicological Sciences. 159, 2, p. 436-448 13 p.

Research output: Contribution to journalArticle

Peroxisome Proliferator-Activated Receptors
Melanoma
Apoptosis
Inflammation
Cells
1 Citation (Scopus)

Procedural povidone iodine rectal preparation reduces bacteriuria and bacteremia following prostate needle biopsy

Allen, J. L., Lehman, K., Dewan, K., Kirimanjeswara, G. S. & Raman, J., Aug 1 2017, In : Canadian Journal of Urology. 24, 4, p. 8883-8889 7 p.

Research output: Contribution to journalArticle

Povidone-Iodine
Bacteriuria
Needle Biopsy
Bacteremia
Prostate
27 Citations (Scopus)

Profiling Ssb-Nascent Chain Interactions Reveals Principles of Hsp70-Assisted Folding

Döring, K., Ahmed, N., Riemer, T., Suresh, H. G., Vainshtein, Y., Habich, M., Riemer, J., Mayer, M. P., O'Brien, Jr., E. P., Kramer, G. & Bukau, B., Jul 13 2017, In : Cell. 170, 2, p. 298-311.e20

Research output: Contribution to journalArticle

Ribosomes
Protein folding
Protein Folding
Substrates
Aromatic Amino Acids
3 Citations (Scopus)

Progression and Characterization of the Accelerated Atherosclerosis in Iliac Artery of New Zealand White Rabbits: Effect of Simvastatin

Kanshana, J. S., Khanna, V., Singh, V., Jain, M., Misra, A., Kumar, S., Farooqui, M., Barthwal, M. K. & Dikshit, M., May 1 2017, In : Journal of Cardiovascular Pharmacology. 69, 5, p. 314-325 12 p.

Research output: Contribution to journalArticle

Simvastatin
Iliac Artery
Atherosclerosis
Atherogenic Diet
Rabbits
6 Citations (Scopus)

Protein-mediated viral latency is a novel mechanism for Merkel cell polyomavirus persistence

Kwun, H. J., Chang, Y. & Moore, P. S., May 16 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 20, p. E4040-E4047

Research output: Contribution to journalArticle

Merkel cell polyomavirus
Virus Latency
Ubiquitin-Protein Ligases
Genome
Proteins
5 Citations (Scopus)

Ranpirnase eradicates human papillomavirus in cultured cells and heals anogenital warts in a Phase i study

Squiquera, L., Taxman, D. J., Brendle, S. A., Torres, R., Sulley, J., Hodge, T., Christensen, N. & Sidransky, D., Jan 1 2017, In : Antiviral Therapy. 22, 3, p. 247-255 9 p.

Research output: Contribution to journalArticle

Warts
Cultured Cells
Antiviral Agents
Cottontail rabbit papillomavirus
Endoribonucleases
1 Citation (Scopus)

Reduced competitive repopulation capacity of multipotential hematopoietic stem cells in the bone marrow of friend virus-infected Fv2-resistant mice

Epperly, M. W., Zhang, X., Fisher, R., Hou, W., Franicola, D., Shields, D., Quickel, M., Giblin, P. H., Wang, H. & Greenberger, J. S., May 1 2017, In : In Vivo. 31, 3, p. 313-320 8 p.

Research output: Contribution to journalArticle

Friend murine leukemia virus
Hematopoietic Stem Cells
Stem cells
Viruses
Bone
7 Citations (Scopus)

Reduced total serum bilirubin levels are associated with ulcerative colitis

Schieffer, K. M., Bruffy, S. M., Rauscher, R., Koltun, W., Yochum, G. & Gallagher, C. J., Jun 1 2017, In : PloS one. 12, 6, e0179267.

Research output: Contribution to journalArticle

colitis
bilirubin
Ulcerative Colitis
Bilirubin
Crohn disease
1 Citation (Scopus)

Reducing persistent polyomavirus infection increases functionality of virus-specific memory CD8 T cells

Qin, Q., Lauver, M., Maru, S., Lin, E. & Lukacher, A. E., Feb 1 2017, In : Virology. 502, p. 198-205 8 p.

Research output: Contribution to journalArticle

Polyomavirus Infections
Polyomavirus
Viruses
T-Lymphocytes
Viral Load
9 Citations (Scopus)

Replication Protein A Prohibits Diffusion of the PCNA Sliding Clamp along Single-Stranded DNA

Hedglin, M. & Benkovic, S., Apr 4 2017, In : Biochemistry. 56, 13, p. 1824-1835 12 p.

Research output: Contribution to journalArticle

Replication Protein A
Single-Stranded DNA
Clamping devices
Proliferating Cell Nuclear Antigen
DNA
5 Citations (Scopus)

RNA-Binding Protein IGF2BP1 in Cutaneous Squamous Cell Carcinoma

Kim, T. W., Havighurst, T., Kim, K. M., Hebbring, S. J., Ye, Z., Aylward, J., Keles, S., Xu, Y. G. & Spiegelman, V., Mar 1 2017, In : Journal of Investigative Dermatology. 137, 3, p. 772-775 4 p.

Research output: Contribution to journalArticle

Neoplasm RNA
Proto-Oncogene Proteins c-myc
RNA-Binding Proteins
Epithelial Cells
3 Citations (Scopus)
DNA Primase
Bacteriophage T4
Recycling
DNA Replication
Holoenzymes
10 Citations (Scopus)

RNA-seq implicates deregulation of the immune system in the pathogenesis of diverticulitis

Schieffer, K. M., Choi, C. S., Emrich, S., Harris, L., Deiling, S., Karamchandani, D. M., Salzberg, A., Kawasawa, Y. I., Yochum, G. S. & Koltun, W. A., Sep 2017, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 313, 3, p. G277-G284

Research output: Contribution to journalArticle

Diverticulitis
Immune System
RNA
Diverticulum
Sigmoid Colon
15 Citations (Scopus)

Role of megakaryocytes in breast cancer metastasis to bone

Jackson, W., Sosnoski, D. M., Ohanessian, S. E., Chandler, P., Mobley, A., Meisel, K. D. & Mastro, A. M., Apr 15 2017, In : Cancer Research. 77, 8, p. 1942-1954 13 p.

Research output: Contribution to journalArticle

Megakaryocytes
Breast Neoplasms
Neoplasm Metastasis
Bone and Bones
Extramedullary Hematopoiesis
6 Citations (Scopus)

Role of P-glycoprotein inhibitors in ceramide-based therapeutics for treatment of cancer

Morad, S. A. F., Davis, T. S., MacDougall, M. R., Tan, S. F., Feith, D. J., Desai, D., Amin, S., Kester, M., Loughran, T. P. & Cabot, M. C., Apr 15 2017, In : Biochemical Pharmacology. 130, p. 21-33 13 p.

Research output: Contribution to journalArticle

Ceramides
P-Glycoprotein
Glycosylation
Tamoxifen
Neoplasms
1 Citation (Scopus)
Chlamydia
Gonorrhea
Sexually Transmitted Diseases
Young Adult
Age Groups

Selective opioid growth factor receptor antagonists based on a stilbene isostere

Stockdale, D. P., Titunick, M. B., Biegler, J. M., Reed, J. L., Hartung, A. M., Wiemer, D. F., McLaughlin, P. & Neighbors, J., Jan 1 2017, In : Bioorganic and Medicinal Chemistry. 25, 16, p. 4464-4474 11 p.

Research output: Contribution to journalArticle

Stilbenes
Amides
Isomers
Opioid Analgesics
Intercellular Signaling Peptides and Proteins
1 Citation (Scopus)

Selenium supplementation through Se-rich dietary matrices can upregulate the anti-inflammatory responses in lipopolysaccharide-stimulated murine macrophages

Dhanjal, N. I. K., Sharma, S., Prabhu, K. S. & Tejo Prakash, N., Nov 2 2017, In : Food and Agricultural Immunology. 28, 6, p. 1374-1392 19 p.

Research output: Contribution to journalArticle

Selenium
lipopolysaccharides
selenium
Triticum
Lipopolysaccharides
7 Citations (Scopus)

Signatures of Nucleotide Analog Incorporation by an RNA-Dependent RNA Polymerase Revealed Using High-Throughput Magnetic Tweezers

Dulin, D., Arnold, J. J., van Laar, T., Oh, H. S., Lee, C., Perkins, A. L., Harki, D. A., Depken, M., Cameron, C. E. & Dekker, N. H., Oct 24 2017, In : Cell Reports. 21, 4, p. 1063-1076 14 p.

Research output: Contribution to journalArticle

RNA Replicase
Nucleotides
Throughput
Ribonucleotides
Antiviral Agents
11 Citations (Scopus)

Single-Cell Virology: On-Chip Investigation of Viral Infection Dynamics

Guo, F., Li, S., Caglar, M. U., Mao, Z., Liu, W., Woodman, A., Arnold, J. J., Wilke, C. O., Huang, T. J. & Cameron, C. E., Nov 7 2017, In : Cell Reports. 21, 6, p. 1692-1704 13 p.

Research output: Contribution to journalArticle

Virology
Virus Diseases
Microfluidics
Kinetics
Population

SKI-178: A multitargeted inhibitor of sphingosine kinase and microtubule dynamics demonstrating therapeutic efficacy in acute myeloid leukemia models

Hengst, J., Dick, T. E., Sharma, A., Doi, K., Hegde, S., Tan, S. F., Geffert, L., Fox, T. E., Sharma, A. K., Desai, D., Amin, S., Kester, M., Loughran, T. P., Paulson, R., Claxton, D., Wang, H-G. & Yun, J., 2017, In : Cancer Translational Medicine. 3, 4, p. 109-121

Research output: Contribution to journalArticle

2 Citations (Scopus)
Parasite Load
T-cells
Malaria
Molecules
Malaria control
10 Citations (Scopus)

Splicing factor SF3B1K700E mutant dysregulates erythroid differentiation via aberrant alternative splicing of transcription factor TAL1

Jin, S., Su, H., Tran, N. T., Song, J., Lu, S. S., Li, Y., Huang, S., Abdel-Wahab, O., Liu, Y. & Zhao, X., May 1 2017, In : PloS one. 12, 5, e0175523.

Research output: Contribution to journalArticle

alternative splicing
Alternative Splicing
RNA splicing
Transcription Factors
transcription factors
5 Citations (Scopus)

Stearoyl-CoA desaturase-1, a novel target of omega-3 fatty acids for reducing breast cancer risk in obese postmenopausal women

Manni, A., Richie, J., Schetter, S., Calcagnotto, A., Trushin, N., Aliaga, C. & El-Bayoumy, K., Jun 1 2017, In : European Journal of Clinical Nutrition. 71, 6, p. 762-765 4 p.

Research output: Contribution to journalArticle

Stearoyl-CoA Desaturase
Omega-3 Fatty Acids
Breast Neoplasms
Body Mass Index
Biomarkers
21 Citations (Scopus)

Structural basis for rifamycin resistance of bacterial RNA polymerase by the three most clinically important RpoB mutations found in Mycobacterium tuberculosis

Molodtsov, V., Scharf, N. T., Stefan, M. A., Garcia, G. A. & Murakami, K., Mar 1 2017, In : Molecular Microbiology. 103, 6, p. 1034-1045 12 p.

Research output: Contribution to journalArticle

Bacterial RNA
DNA-Directed RNA Polymerases
Mycobacterium tuberculosis
Tuberculosis
Mutation
13 Citations (Scopus)

Structural heterogeneity in the intrinsically disordered RNA polymerase II C-terminal domain

Portz, B., Lu, F., Gibbs, E. B., Mayfield, J. E., Rachel Mehaffey, M., Zhang, Y. J., Brodbelt, J. S., Showalter, S. A. & Gilmour, D. S., May 12 2017, In : Nature communications. 8, 15231.

Research output: Contribution to journalArticle

RNA Polymerase III
Phosphorylation
RNA Polymerase II
Drosophila melanogaster
Consensus Sequence
1 Citation (Scopus)

Structural model of the tubular assembly of the rous sarcoma virus capsid protein

Jeon, J., Qiao, X., Hung, I., Mitra, A. K., Desfosses, A., Huang, D., Gorkov, P. L., Craven, R., Kingston, R. L., Gan, Z., Zhu, F. & Chen, B., Feb 8 2017, In : Journal of the American Chemical Society. 139, 5, p. 2006-2013 8 p.

Research output: Contribution to journalArticle

Rous sarcoma virus
Capsid
Structural Models
Capsid Proteins
Viruses

Substrate Specificity of the Kinase P-TEFb towards the RNA Polymerase II C-Terminal Domain

Gibbs, E. B., Laremore, T. N., Usher, G. A., Portz, B., Cook, E. C. & Showalter, S. A., Nov 7 2017, In : Biophysical journal. 113, 9, p. 1909-1911 3 p.

Research output: Contribution to journalArticle

RNA Polymerase III
Peptide Elongation Factors
RNA Polymerase II
Positive Transcriptional Elongation Factor B
Substrate Specificity
16 Citations (Scopus)

Successful chemoimmunotherapy against hepatocellular cancer in a novel murine model

Li, G., Liu, D., Cooper, T., Kimchi, E. T., Qi, X., Avella, D. M., Li, N., Yang, Q., Kester, M., Rountree, C. B., Kaifi, J. T., Cole, D. J., Rockey, D. C., Schell, T. & Staveley-O'Carroll, K. F., Jan 1 2017, In : Journal of Hepatology. 66, 1, p. 75-85 11 p.

Research output: Contribution to journalArticle

Liver Neoplasms
Neoplasms
Neoplasm Antigens
T-Lymphocytes
Programmed Cell Death 1 Receptor
8 Citations (Scopus)

Sunitinib represses regulatory T cells to overcome immunotolerance in a murine model of hepatocellular cancer

Liu, D., Li, G., Avella, D. M., Kimchi, E. T., Kaifi, J. T., Rubinstein, M. P., Camp, E. R., Rockey, D. C., Schell, T. & Staveley-O'Carroll, K. F., Sep 20 2017, (Accepted/In press) In : OncoImmunology.

Research output: Contribution to journalArticle

Regulatory T-Lymphocytes
Liver Neoplasms
Neoplasm Antigens
Neoplasms
T-Lymphocytes
18 Citations (Scopus)

Supplementation of Low- and High-fat Diets with Fermentable Fiber Exacerbates Severity of DSS-induced Acute Colitis

Miles, J. P., Zou, J., Kumar, M. V., Pellizzon, M., Ulman, E., Ricci, M., Gewirtz, A. T. & Chassaing, B., Jul 1 2017, In : Inflammatory bowel diseases. 23, 7, p. 1133-1143 11 p.

Research output: Contribution to journalArticle

Fat-Restricted Diet
Dextran Sulfate
High Fat Diet
Colitis
Inulin
5 Citations (Scopus)

Targeting protein geranylgeranylation slows tumor development in a murine model of prostate cancer metastasis

Reilly, J. E., Neighbors, J. & Hohl, R., Nov 2 2017, In : Cancer Biology and Therapy. 18, 11, p. 872-882 11 p.

Research output: Contribution to journalArticle

Protein Prenylation
Prostatic Neoplasms
Neoplasm Metastasis
Tumor Burden
Farnesyltranstransferase
7 Citations (Scopus)

TAX1BP1 restrains virus-induced apoptosis by facilitating itch-mediated degradation of the mitochondrial adaptor MAVS

Choi, Y. B., Shembade, N., Parvatiyar, K., Balachandran, S. & Harhaj, E., Jan 1 2017, In : Molecular and cellular biology. 37, 1, e00422-16.

Research output: Contribution to journalArticle

RNA Virus Infections
Apoptosis
Viruses
Sendai virus
Virus Activation
7 Citations (Scopus)

TCF7L1 recruits CtBP and HDAC1 to repress DICKKOPF4 gene expression in human colorectal cancer cells

Eshelman, M. A., Shah, M., Raup-Konsavage, W. M., Rennoll, S. A. & Yochum, G., Jun 3 2017, In : Biochemical and Biophysical Research Communications. 487, 3, p. 716-722 7 p.

Research output: Contribution to journalArticle

Histone Deacetylase 1
TCF Transcription Factors
Gene expression
Colorectal Neoplasms
Cells
8 Citations (Scopus)
Virus Diseases
T-Lymphocytes
Brain
Antigens
Epitopes
24 Citations (Scopus)

Tet2 loss leads to hypermutagenicity in haematopoietic stem/progenitor cells

Pan, F., Wingo, T. S., Zhao, Z., Gao, R., Makishima, H., Qu, G., Lin, L., Yu, M., Ortega, J. R., Wang, J., Nazha, A., Chen, L., Yao, B., Liu, C., Chen, S., Weeks, O., Ni, H., Phillips, B. L., Huang, S., Wang, J. & 8 others, He, C., Li, G. M., Radivoyevitch, T., Aifantis, I., MacIejewski, J. P., Yang, F. C., Jin, P. & Xu, M., Jan 1 2017, In : Nature communications. 8, 15102.

Research output: Contribution to journalArticle

stem cells
mutations
Hematopoietic Stem Cells
Stem cells
Hematologic Neoplasms
7 Citations (Scopus)

The histone acetyltransferase Gcn5 positively regulates T Cell activation

Gao, B., Kong, Q., Zhang, Y., Yun, C., Dent, S. Y. R., Song, J., Zhang, D. D., Wang, Y., Li, X. & Fang, D., May 15 2017, In : Journal of Immunology. 198, 10, p. 3927-3938 12 p.

Research output: Contribution to journalArticle

Histone Acetyltransferases
T-Lymphocytes
Proteins
Interleukin-2
Autoimmune Experimental Encephalomyelitis