Cancer Institute, Mechanisms of Carcinogenesis

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Research Output 1963 2020

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Article
1977
2 Citations (Scopus)

Phorbol esters and the mixed lymphocyte response

Mastro, A. M., Krupa, T. & Mueller, G. C., Jan 1 1977, In : Journal of Cell Biology. 75, 2 II

Research output: Contribution to journal › Article

Phorbol Esters
Lymphocytes
40 Citations (Scopus)

Studies on models for tetrahydrofolic acid. 8. Hydrolysis and methoxyaminolysis of amidines

Burdick, B. A., Benkovic, P. A. & Benkovic, S., Jan 1 1977, In : Journal of the American Chemical Society. 99, 17, p. 5716-5725 10 p.

Research output: Contribution to journal › Article

Amidines
Isomers
Hydrolysis
Thermodynamics
Kinetics
1976
12 Citations (Scopus)

Annelation of imines to β-lactams at low temperatures

Manhas, M. S., Amin, S., Ram, B. & Bose, A. K., Oct 1 1976, In : Synthesis (Germany). 1976, 10, p. 689-690 2 p.

Research output: Contribution to journal › Article

Imines
beta-Lactams
Temperature
Lactams
12 Citations (Scopus)

Heterocyclic compounds. VII. Synthesis of thiadiazasteroid analogs

Manhas, M. S., Rao, V. V. & Amin, S., Jan 1 1976, In : Journal of Heterocyclic Chemistry. 13, 4, p. 821-824 4 p.

Research output: Contribution to journal › Article

Heterocyclic Compounds
Lactams
Steroids
Derivatives
Cyclization
7 Citations (Scopus)

Phosphoproteins of the cell surface as generated by endogenous or exogenous proteins kinase: Stability of the 32P-labelled product

Kinzel, V., Kübler, D., Mastro, A. M. & Rozengurt, E., May 20 1976, In : BBA - Protein Structure. 434, 1, p. 281-285 5 p.

Research output: Contribution to journal › Article

Protein Stability
Phosphoproteins
Threonine
Cell membranes
Protein Kinases
14 Citations (Scopus)

Studies on lactams. Part 45. Some carbocyclic analogues of cephalosporin

Bose, A. K., Amin, S. G., Kapur, J. C. & Manhas, M. S., Dec 1 1976, In : Journal of the Chemical Society, Perkin Transactions 1. 20, p. 2193-2197 5 p.

Research output: Contribution to journal › Article

Lactams
Cephalosporins
Chlorides
Imines
Penicillin G
24 Citations (Scopus)

α-Substituted β-Lactams Via A Convenient Annelation Of Imines

Manhas, M. S., Lai, B., Amin, S. & Bose, A. K., Jan 1 1976, In : Synthetic Communications. 6, 6, p. 435-441 7 p.

Research output: Contribution to journal › Article

Imines
beta-Lactams
1975
47 Citations (Scopus)

[60] Fructose-1,6-diphosphatase from Rabbit Liver

Ulm, E. H., Pogell, B. M., deMaine, M. M., Libby, C. B. & Benkovic, S., Jan 1 1975, In : Methods in Enzymology. 42, C, p. 369-374 6 p.

Research output: Contribution to journal › Article

Fructose-Bisphosphatase
Spectrophotometry
Adenosine Monophosphate
Edetic Acid
Chromatography
35 Citations (Scopus)

Catalysis of Phosphoryl Group Transfer. The Role of Divalent Metal Ions in the Hydrolysis of Lactic Acid O-Phenyl Phosphate and Salicylic Acid O-Aryl Phosphates

Steffens, J. J., Siewers, I. J. & Benkovic, S., Jun 1 1975, In : Biochemistry. 14, 11, p. 2431-2440 10 p.

Research output: Contribution to journal › Article

Salicylic Acid
Catalysis
Metal ions
Hydrolysis
Lactic Acid

Frontiers in chemistry day: Oxygen bicentennial symposium

Benkovic, S., 1975, In : Journal of Chemical Education. 52, 2, p. 15-20 6 p.

Research output: Contribution to journal › Article

chemistry
Oxygen
8 Citations (Scopus)

The Anomeric Specificity of Yeast Pyruvate Kinase toward Activation by D-Fructose l,6-Bisphosphatete

Fishbein, R., Benkovic, P. A. & Benkovic, S., Sep 1 1975, In : Biochemistry. 14, 18, p. 4060-4063 4 p.

Research output: Contribution to journal › Article

Pyruvate Kinase
Fructose
Yeast
Yeasts
Chemical activation
1974
7 Citations (Scopus)

A stereospecific synthesis of β-alkoxy-β-lactams (1)

Bose, A. K., Kapur, J. C., Amin, S. G. & Manhas, M. S., 1974, In : Tetrahedron Letters. 15, 22, p. 1917-1920 4 p.

Research output: Contribution to journal › Article

beta-Lactams
alkoxyl radical
10 Citations (Scopus)

Iodination of plasma membrane proteins of BHK cells in different growth states

Mastro, A. M., Beer, C. T. & Mueller, G. C., May 30 1974, In : BBA - Biomembranes. 352, 1, p. 38-51 14 p.

Research output: Contribution to journal › Article

Halogenation
Cell membranes
Blood Proteins
Membrane Proteins
Cell Membrane
132 Citations (Scopus)

Synergistic action of phorbol esters in mitogen-activated bovine lymphocytes

Mastro, A. M. & Mueller, G. C., Jan 1 1974, In : Experimental Cell Research. 88, 1, p. 40-46 7 p.

Research output: Contribution to journal › Article

Phorbol Esters
Mitogens
Lymphocytes
Phytohemagglutinins
Concanavalin A
1973
25 Citations (Scopus)

Effect of divalent metal ions on the intramolecular nucleophilic catalysis of phosphate diester hydrolysis

Steffens, J. J., Sampson, E. J., Siewers, I. J. & Benkovic, S., Feb 1 1973, In : Journal of the American Chemical Society. 95, 3, p. 936-938 3 p.

Research output: Contribution to journal › Article

Catalysis
Metal ions
Hydrolysis
Phosphates
Metals
113 Citations (Scopus)

Enrichment of cell types from the rat adenohypophysis by sedimentation at unit gravity

Hymer, W. C., Evans, W. H., Kraicer, J., Mastro, A., Davis, J. & Griswold, E., Jan 1973, In : Endocrinology. 92, 1, p. 275-287 13 p.

Research output: Contribution to journal › Article

Anterior Pituitary Gland
Gravitation
Cell Separation
Thyrotrophs
Lactotrophs
12 Citations (Scopus)

Internal Return of Caged Geminate Radicals from 9-azophenyl-2-bromo-9-methylfluorene. Viscosity-Dependent Rotation of Caged Radicals

Steffens, J. J., Sampson, E. J., Siewers, I. J. & Benkovic, S., Feb 1 1973, In : Journal of the American Chemical Society. 95, 3, p. 938-939 2 p.

Research output: Contribution to journal › Article

Viscosity
9-methylfluorene
20 Citations (Scopus)

Intramolecular and Divalent Metal Ion Catalysis. The Hydrolytic Mechanism of O-Phenyl N-(Glycyl)phosphoramidate

Sampson, E. J., Fedor, J., Benkovic, P. A. & Benkovic, S., Apr 1 1973, In : Journal of Organic Chemistry. 38, 7, p. 1301-1306 6 p.

Research output: Contribution to journal › Article

Catalysis
Metal ions
Hydrolysis
Phosphates
Hydroxylamine
15 Citations (Scopus)

The effects of age and oestrone treatment on DNA polymerase activity in anterior pituitary glands of male rats

Mastro, A. & Hymer, W. C., Jan 1 1973, In : Journal of Endocrinology. 59, 1, p. 107-119 13 p.

Research output: Contribution to journal › Article

Anterior Pituitary Gland
Estrone
DNA-Directed DNA Polymerase
DNA
Deoxyribonucleosides
1972
16 Citations (Scopus)

Chapter 1 Hydrolytic Reactions of Inorganic Esters

Benkovic, S., Dec 1 1972, In : Comprehensive Chemical Kinetics. 10, C, p. 1-56 56 p.

Research output: Contribution to journal › Article

esters
Esters
42 Citations (Scopus)

Heterocyclic Compounds. 4.f Synthesis and Antiinflammatory Activity of Some Substituted Thienopyrimidones

Manhas, M. S., Sharma, S. D. & Amin, S., Jan 1 1972, In : Journal of Medicinal Chemistry. 15, 1, p. 106-107 2 p.

Research output: Contribution to journal › Article

Pyrimidinones
Heterocyclic Compounds
Thiophenes
Lethal Dose 50
Oral Administration
29 Citations (Scopus)

Magnetic resonance studies of the anomeric distribution and manganese binding properties of fructose phosphates

Benkovic, S., Engle, J. L. & Mildvan, A. S., May 26 1972, In : Biochemical and Biophysical Research Communications. 47, 4, p. 852-858 7 p.

Research output: Contribution to journal › Article

Magnetic resonance
Manganese
Fructose
Magnetic Resonance Spectroscopy
Phosphates
1971

Thiophene Analogues of Peedianwridcne

Bost, A. K., Han ha, M. S., Sharme, S. O., Amin, S. G. & Chawla, H. P. S., Jan 1 1971, In : Synthetic Communications. 1, 1, p. 33-36 4 p.

Research output: Contribution to journal › Article

Thiophenes
1970
27 Citations (Scopus)

DNA synthesis in the anterior pituitary of the male rat: Effect of castration and photoperiod

Hymer, W. C., Mastro, A. M. & Griswold, E., Jan 1 1970, In : Science. 167, 3925, p. 1629-1631 3 p.

Research output: Contribution to journal › Article

Castration
Photoperiod
Anterior Pituitary Gland
Basophils
DNA
33 Citations (Scopus)

Organic and Biological Chemistry: Studies on Models for Tetrahydrofolic Acid. II. Additional Observations on the Mechanism for Condensation of Formaldehyde with Tetrahydroquinoxaline Analogs

Benkovic, S., Benkovic, P. A. & Chrzanowski, R., Feb 1 1970, In : Journal of the American Chemical Society. 92, 3, p. 523-528 6 p.

Research output: Contribution to journal › Article

Imidazolidines
Organic Chemistry
Catalysis
Dehydration
Formaldehyde
25 Citations (Scopus)

Studies in Sulfate Esters. V. The Mechanism of Hydrolysis of Phenyl Phosphosulfate, a Model System for 3′-Phosphoadenosine 5′-Phosphosulfate

Benkovic, S. & Hevey, R. C., Aug 1 1970, In : Journal of the American Chemical Society. 92, 16, p. 4971-4977 7 p.

Research output: Contribution to journal › Article

Phosphoadenosine Phosphosulfate
Sulfates
Hydrolysis
Esters
Adenosine Phosphosulfate
1969
18 Citations (Scopus)

DNA synthesis in adult rat anterior pituitary glands in organ culture

Mastro, A. M., Hymer, W. C. & Therrien, C. D., Jan 1 1969, In : Experimental Cell Research. 54, 3, p. 407-414 8 p.

Research output: Contribution to journal › Article

Anterior Pituitary Gland
Organ Culture Techniques
Thymidine
DNA
Basophils
22 Citations (Scopus)

DNA synthesis in the rat anterior pituitary: an electron microscope radioautographic study.

Mastro, A., Shelton, E. & Hymer, W. C., Dec 1969, In : The Journal of cell biology. 43, 3, p. 626-629 4 p.

Research output: Contribution to journal › Article

Cytoplasmic Granules
Tritium
Pituitary Gland
Autoradiography
Electron Microscopy
22 Citations (Scopus)

Kinetic Detection of the Imminium Cation in Formaldehyde-Amine Condensations in Neutral Aqueous Solution

Benkovic, S., Benkovic, P. A. & Comfort, D. R., Jan 1 1969, In : Journal of the American Chemical Society. 91, 7, p. 1860-1861 2 p.

Research output: Contribution to journal › Article

Formaldehyde
Amines
Cations
Condensation
Positive ions
1968
19 Citations (Scopus)

Metal Ion Catalysis of Phosphoryl Transfer from Phosphoenolpyruvate

Benkovic, S. & Schray, K. J., Nov 1 1968, In : Biochemistry. 7, 11, p. 4097-4102 6 p.

Research output: Contribution to journal › Article

Phosphoenolpyruvate
Catalysis
Mercury
Metal ions
Metals
15 Citations (Scopus)

Studies on Sulfate Esters. III. A Comparison of the Solvolyses of Salicyl Sulfate and Sulfur Trioxide

Benkovic, S. & Benkovic, P. A., Jan 1 1968, In : Journal of the American Chemical Society. 90, 10, p. 2646-2650 5 p.

Research output: Contribution to journal › Article

Isomers
Sulfates
Esters
Sulfur
Methanol
36 Citations (Scopus)

The Kinetics and Mechanisms of Phosphoenolpyruvate Hydrolysis

Benkovic, S. & Schray, K. J., Nov 1 1968, In : Biochemistry. 7, 11, p. 4090-4096 7 p.

Research output: Contribution to journal › Article

Phosphoenolpyruvate
Hydrolysis
Kinetics
Phosphates
Ketones
1966
100 Citations (Scopus)

Studies on Sulfate Esters. I. Nucleophilic Reactions of Amines with p-Nitrophenyl Sulfate

Benkovic, S. & Benkovic, P. A., Jan 1 1966, In : Journal of the American Chemical Society. 88, 23, p. 5504-5511 8 p.

Research output: Contribution to journal › Article

Sulfates
Amines
Esters
Hydrolysis
Phosphates
24 Citations (Scopus)

Studies on Sulfate Esters. II. Carboxyl Group Catalysis in the Hydrolysis of Salicyl Sulfate

Benkovic, S., Jan 1 1966, In : Journal of the American Chemical Society. 88, 23, p. 5511-5515 5 p.

Research output: Contribution to journal › Article

Catalysis
Sulfates
Hydrolysis
Esters
Acids
1963
85 Citations (Scopus)

A Comparison of the Bimolecular and Intramolecular Nucleophilic Catalysis of the Hydrolysis of Substituted Phenyl Acylates by the Dimethylamino Group

Bruice, T. C. & Benkovic, S., Jan 1 1963, In : Journal of the American Chemical Society. 85, 1, p. 1-8 8 p.

Research output: Contribution to journal › Article

Catalysis
Anions
Hydrolysis
Rate constants
Esters