Research Output 1963 2020

Filter
Article
Article
4 Citations (Scopus)

VISTA is highly expressed on MDSCs and mediates an inhibition of T cell response in patients with AML

Wang, L., Jia, B., Claxton, D. F., Ehmann, W. C., Rybka, W. B., Mineishi, S., Naik, S., Khawaja, M. R., Sivik, J., Han, J., Hohl, R. J. & Zheng, H., Sep 2 2018, In : OncoImmunology. 7, 9, e1469594.

Research output: Contribution to journalArticle

Acute Myeloid Leukemia
T-Lymphocytes
Leukemia
Myeloid-Derived Suppressor Cells
Immunoglobulin Domains
80 Citations (Scopus)

Visualization of a missing link in retrovirus capsid assembly

Cardone, G., Purdy, J. G., Cheng, N., Craven, R. C. & Steven, A. C., Feb 5 2009, In : Nature. 457, 7230, p. 694-698 5 p.

Research output: Contribution to journalArticle

Capsid
Retroviridae
Fullerenes
Rous sarcoma virus
Capsid Proteins
49 Citations (Scopus)

Visualization of polyoma virus-specific CD8+ T cells in vivo during infection and tumor rejection

Lukacher, A. E., Moser, J. M., Hadley, A. & Altman, J. D., Sep 15 1999, In : Journal of Immunology. 163, 6, p. 3369-3378 10 p.

Research output: Contribution to journalArticle

Polyomavirus
T-Lymphocytes
Infection
Neoplasms
Peptides
13 Citations (Scopus)

Visualization of protein kinases in lymphocytes stimulated to proliferate with concanavalin A or inhibited with A phorbol ester

Iyer, A. P., Pishak, S. A., Sniezek, M. J. & Mastro, A. M., May 31 1984, In : Biochemical and Biophysical Research Communications. 121, 1, p. 392-399 8 p.

Research output: Contribution to journalArticle

Lymphocytes
Phorbol Esters
Concanavalin A
Lectins
Protein Kinases
262 Citations (Scopus)

Visualizing priming of virus-specific CD8+ T cells by infected dendritic cells in vivo

Norbury, C. C., Malide, D., Gibbs, J. S., Bennink, J. R. & Yewdell, J. W., Jan 1 2002, In : Nature Immunology. 3, 3, p. 265-271 7 p.

Research output: Contribution to journalArticle

Dendritic Cells
Vaccinia virus
Antigen-Presenting Cells
Viruses
T-Lymphocytes
10 Citations (Scopus)

Vitamin A deficiency exacerbates murine lyme arthritis

Cantorna, M. T. & Hayes, C. E., Jan 1 1996, In : Journal of Infectious Diseases. 174, 4, p. 747-751 5 p.

Research output: Contribution to journalArticle

Vitamin A Deficiency
Lyme Disease
Vitamin A
Interferons
Spirochaetales
13 Citations (Scopus)
Vitamin A Deficiency
Vitamin A
Metabolism
Homeostasis
Liver
112 Citations (Scopus)

Vitamin A deficiency results in a priming environment conducive for Th1 cell development

Cantorna, M. T., Nashold, F. E. & Hayes, C. E., Jun 1995, In : European Journal of Immunology. 25, 6, p. 1673-1679 7 p.

Research output: Contribution to journalArticle

Vitamin A Deficiency
Th1 Cells
Interferons
Vitamin A
T-Lymphocytes
64 Citations (Scopus)

Vitamin A down-regulation of IFN-γ synthesis in cloned mouse Th1 lymphocytes depends on the CD28 costimulatory pathway

Cantorna, M. T., Nashold, F. E., Chun, T. Y. & Hayes, C. E., Apr 15 1996, In : Journal of Immunology. 156, 8, p. 2674-2679 6 p.

Research output: Contribution to journalArticle

Th1 Cells
Tretinoin
Vitamin A
Th2 Cells
Down-Regulation
70 Citations (Scopus)

Vitamin D, immune regulation, the microbiota, and inflammatory bowel disease

Cantorna, M. T., McDaniel, K., Bora, S., Chen, J. & James, J., Nov 12 2014, In : Experimental Biology and Medicine. 239, 11, p. 1524-1530 7 p.

Research output: Contribution to journalArticle

Microbiota
Inflammatory Bowel Diseases
Vitamin D
Homeostasis
Calcitriol Receptors
41 Citations (Scopus)

Vitamin D, invariant natural killer T-cells and experimental autoimmune disease

Cantorna, M. T., Zhao, J. & Yang, L., Feb 1 2012, In : Proceedings of the Nutrition Society. 71, 1, p. 62-66 5 p.

Research output: Contribution to journalArticle

Natural Killer T-Cells
Vitamin D
Autoimmune Diseases
Vitamin D Deficiency
Calcitriol
1 Citation (Scopus)

Vitamin D and lung infection

Cantorna, M. T., Jan 1 2016, In : Infection and Immunity. 84, 11, p. 3094-3096 3 p.

Research output: Contribution to journalArticle

Vitamin D
Lung
Infection
Pneumonia
Viruses
70 Citations (Scopus)

Vitamin D and multiple sclerosis: An update

Cantorna, M. T., Oct 1 2008, In : Nutrition reviews. 66, SUPPL.2, p. S135-S138

Research output: Contribution to journalArticle

Vitamin D
Multiple Sclerosis
Hygiene Hypothesis
Sunlight
Observational Studies
190 Citations (Scopus)

Vitamin D and Multiple Sclerosis

Hayes, C. E., Cantorna, M. T. & DeLuca, H. F., Dec 1 1997, In : Experimental Biology and Medicine. 216, 1, p. 21-27 7 p.

Research output: Contribution to journalArticle

Cholecalciferol
Vitamin D
Multiple Sclerosis
Calcitriol
Coastal zones
204 Citations (Scopus)
Calcitriol Receptors
Innate Immunity
Vitamin D
Dextran Sulfate
Wounds and Injuries

Vitamin d as an immune system regulator: Inhibiton of experimental autoimmune encephalomyelitis

Cantorna, M. T., Deluca, H. F. & Haves, C. E., Dec 1 1996, In : FASEB Journal. 10, 6, p. A1314

Research output: Contribution to journalArticle

Autoimmune Experimental Encephalomyelitis
Immune system
encephalitis
vitamin D
Vitamin D
39 Citations (Scopus)

Vitamin D inhibits the occurrence of experimental cerebral malaria in mice by suppressing the host inflammatory response

He, X., Yan, J., Zhu, X., Wang, Q., Pang, W., Qi, Z., Wang, M., Luo, E., Parker, D. M., Cantorna, M. T., Cui, L. & Cao, Y., Aug 1 2014, In : Journal of Immunology. 193, 3, p. 1314-1323 10 p.

Research output: Contribution to journalArticle

Cerebral Malaria
Plasmodium berghei
Vitamin D
Chemokine CXCL9
Brain
6 Citations (Scopus)

Vitamin D is required for ILC3 derived IL-22 and protection from Citrobacter rodentium infection

Lin, Y. D., Arora, J., Diehl, K., Bora, S. A. & Cantorna, M. T., Jan 1 2019, In : Frontiers in immunology. 10, JAN

Research output: Contribution to journalArticle

Citrobacter rodentium
Vitamin D
Infection
interleukin-22
159 Citations (Scopus)

Vitamin D receptor-deficient mice fail to develop experimental allergic asthma

Wittke, A., Weaver, V., Mahon, B. D., August, A. & Cantorna, M. T., Sep 1 2004, In : Journal of Immunology. 173, 5, p. 3432-3436 5 p.

Research output: Contribution to journalArticle

Calcitriol Receptors
Asthma
Vitamin D
Cytokines
Inflammation
67 Citations (Scopus)

Vitamin D receptor expression by the lung micro-environment is required for maximal induction of lung inflammation

Wittke, A., Chang, A., Froicu, M., Harandi, O. F., Weaver, V., August, A., Paulson, R. & Cantorna, M. T-A., Apr 15 2007, In : Archives of Biochemistry and Biophysics. 460, 2, p. 306-313 8 p.

Research output: Contribution to journalArticle

Calcitriol Receptors
Pneumonia
Lung
Vitamin D Deficiency
Vitamin D
49 Citations (Scopus)
Calcitriol Receptors
Inflammation
T-Lymphocytes
Colitis
Inflammatory Bowel Diseases
93 Citations (Scopus)

Vitamin D receptor is required to control gastrointestinal immunity in IL-10 knockout mice

Froicu, M., Zhu, Y. & Cantorna, M. T-A., Mar 1 2006, In : Immunology. 117, 3, p. 310-318 9 p.

Research output: Contribution to journalArticle

Calcitriol Receptors
Knockout Mice
Interleukin-10
Immunity
Inflammation
149 Citations (Scopus)

Vitamin D regulates the gut microbiome and protects mice from dextran sodium sulfate-induced coliti

Ooi, J. H., Li, Y., Rogers, C. J. & Cantorna, M. T., Oct 22 2013, In : Journal of Nutrition. 143, 10, p. 1679-1686 8 p.

Research output: Contribution to journalArticle

Dextran Sulfate
Calcitriol Receptors
Vitamin D
Knockout Mice
Feces

Vitamin D Regulates the Microbiota to Control the Numbers of RORγt/FoxP3+ Regulatory T Cells in the Colon

Cantorna, M. T., Lin, Y. D., Arora, J., Bora, S., Tian, Y., Nichols, R. G. & Patterson, A. D., Jan 1 2019, In : Frontiers in immunology. 10, 1 p.

Research output: Contribution to journalArticle

Open Access
Microbiota
Regulatory T-Lymphocytes
Vitamin D
Colon
Colitis
56 Citations (Scopus)

Vitamin D regulation of immune function in the gut: Why do T cells have vitamin D receptors?

Ooi, J. H., Chen, J. & Cantorna, M. T., Feb 1 2012, In : Molecular Aspects of Medicine. 33, 1, p. 77-82 6 p.

Research output: Contribution to journalArticle

Calcitriol Receptors
T-cells
Vitamin D
T-Lymphocytes
Natural Killer T-Cells
135 Citations (Scopus)

Voltage-gated Na+ channel SCN5A is a key regulator of a gene transcriptional network that controls colon cancer invasion

House, C. D., Vaske, C. J., Schwartz, A. M., Obias, V., Frank, B., Luu, T., Sarvazyan, N., Irby, R., Strausberg, R. L., Hales, T. G., Stuart, J. M. & Lee, N. H., Sep 1 2010, In : Cancer Research. 70, 17, p. 6957-6967 11 p.

Research output: Contribution to journalArticle

Gene Regulatory Networks
Regulator Genes
Colonic Neoplasms
Small Interfering RNA
Staining and Labeling
3 Citations (Scopus)

Vorinostat downregulates CD30 and decreases brentuximab vedotin efficacy in human lymphocytes

Hasanali, Z. S., Epner, E. M., Feith, D. J., Loughran, T. P. & Sample, C. E., Dec 1 2014, In : Molecular cancer therapeutics. 13, 12, p. 2784-2792 9 p.

Research output: Contribution to journalArticle

Down-Regulation
Lymphocytes
Therapeutics
Neoplasms
vorinostat
2 Citations (Scopus)

VPS37A directs ESCRT recruitment for phagophore closure

Takahashi, Y., Liang, X., Hattori, T., Tang, Z., He, H., Chen, H., Liu, X., Abraham, T., Imamura-Kawasawa, Y., Buchkovich, N. J., Young, M. M. & Wang, H. G., Oct 7 2019, In : The Journal of cell biology. 218, 10, p. 3336-3354 19 p.

Research output: Contribution to journalArticle

Open Access
Endosomal Sorting Complexes Required for Transport
Clustered Regularly Interspaced Short Palindromic Repeats
Multivesicular Bodies
Ubiquitin
Epidermal Growth Factor Receptor

v-Src transformation is mediated through farnesylated proteins

Teng, S., Sun, J., Irby, R., Hamilton, A. D., Sebti, S. & Yeatman, T. J., Jan 1 2001, In : Journal of Surgical Research. 99, 2, p. 343-346 4 p.

Research output: Contribution to journalArticle

Transferases
Proteins
Western Blotting
Prenylation
Antibodies
101 Citations (Scopus)

VWF-mediated leukocyte recruitment with chromatin decondensation by PAD4 increases myocardial ischemia/reperfusion injury in mice

Savchenko, A. S., Borissoff, J. I., Martinod, K., De Meyer, S. F., Gallant, M., Erpenbeck, L., Brill, A., Wang, Y. & Wagner, D. D., Jan 2 2014, In : Blood. 123, 1, p. 141-148 8 p.

Research output: Contribution to journalArticle

Myocardial Reperfusion Injury
von Willebrand Factor
Reperfusion Injury
Chromatin
Myocardial Ischemia
24 Citations (Scopus)

Watching the bacteriophage N4 RNA polymerase transcription by time-dependent soak-trigger-freeze x-ray crystallography

Basu, R. S. & Murakami, K. S., Feb 1 2013, In : Journal of Biological Chemistry. 288, 5, p. 3305-3311 7 p.

Research output: Contribution to journalArticle

Bacteriophage N4
Crystallography
Bacteriophages
DNA-Directed RNA Polymerases
Transcription
17 Citations (Scopus)

Western diet induces colonic nitrergic myenteric neuropathy and dysmotility in mice via saturated fatty acid- and lipopolysaccharide-induced TLR4 signalling

Reichardt, F., Chassaing, B., Nezami, B. G., Li, G., Tabatabavakili, S., Mwangi, S., Uppal, K., Liang, B., Vijay-Kumar, M., Jones, D., Gewirtz, A. T. & Srinivasan, S., Mar 1 2017, In : Journal of Physiology. 595, 5, p. 1831-1846 16 p.

Research output: Contribution to journalArticle

Toll-Like Receptor 4
Lipopolysaccharides
Fatty Acids
Dysbiosis
Nonesterified Fatty Acids
70 Citations (Scopus)

What is a microsatellite: A computational and experimental definition based upon repeat mutational behavior at A/T and GT/AC repeats

Kelkar, Y. D., Strubczewski, N., Hile, S. E., Chiaromonte, F., Eckert, K. A. & Makova, K. D., Oct 29 2010, In : Genome biology and evolution. 2, 1, p. 620-635 16 p.

Research output: Contribution to journalArticle

Microsatellite Repeats
microsatellite repeats
polymorphism
genetic polymorphism
genome
14 Citations (Scopus)

White Button mushrooms increase microbialdiversity and accelerate the resolution of Citrobacter rodentium infection in mice

Varshney, J., Ooi, J. H., Jayarao, B. M., Albert, I., Fisher, J., Smith, R. L., Patterson, A. D. & Cantorna, M. T., Apr 1 2013, In : Journal of Nutrition. 143, 4, p. 526-532 7 p.

Research output: Contribution to journalArticle

Citrobacter rodentium
Agaricales
Diet
Metabolome
Infection
5 Citations (Scopus)
Whole-Body Irradiation
Prostatic Neoplasms
Prostate
T-Lymphocytes
Adoptive Immunotherapy
3 Citations (Scopus)

Why do CD8+T cells become indifferent to tumors: A dynamic modeling approach

Campbell, C., Zhang, R., Haley, J. S., Liu, X., Loughran, T., Schell, T. D., Albert, R. & Thakar, J., Dec 1 2011, In : Frontiers in Physiology. JUL, Article 32.

Research output: Contribution to journalArticle

T-Lymphocytes
Neoplasms
Transgenic Mice
Apoptosis
Tumor Escape
42 Citations (Scopus)

Why do T cells express the vitamin D receptor?

Cantorna, M. T., Jan 2011, In : Annals of the New York Academy of Sciences. 1217, 1, p. 77-82 6 p.

Research output: Contribution to journalArticle

Calcitriol Receptors
T-cells
Vitamin D
T-Lymphocytes
Autoimmunity
10 Citations (Scopus)

Widespread and precise reprogramming of yeast protein-genome interactions in response to heat shock

Vinayachandran, V., Reja, R., Rossi, M. J., Park, B., Rieber, L., Mittal, C., Mahony, S. & Pugh, B. F., Mar 2018, In : Genome research. 28, 3, p. 357-366 10 p.

Research output: Contribution to journalArticle

Heat-Shock Response
Fungal Proteins
Genome
Shock
Nucleosomes
65 Citations (Scopus)

Widespread nonhematopoietic tissue distribution by transplanted human progenitor cells with high aldehyde dehydrogenase activity

Hess, D. A., Craft, T. P., Wirthlin, L., Hohm, S., Zhou, P., Eades, W. C., Creer, M. H., Sands, M. S. & Nolta, J. A., Mar 1 2008, In : STEM CELLS. 26, 3, p. 611-620 10 p.

Research output: Contribution to journalArticle

Aldehyde Dehydrogenase
Tissue Distribution
Stem Cells
Phenotype
Blood Vessels
129 Citations (Scopus)

Wnt/β-catenin signaling induces the expression and activity of βTrCP ubiquitin ligase receptor

Spiegelman, V. S., Slaga, T. J., Pagano, M., Minamoto, T., Ronai, Z. & Fuchs, S. Y., Jan 1 2000, In : Molecular cell. 5, 5, p. 877-882 6 p.

Research output: Contribution to journalArticle

Catenins
Ubiquitin-Protein Ligases
Proteins
Ubiquitination
Transcriptional Activation
158 Citations (Scopus)

Wnt/β-catenin signaling regulates yes-associated protein (YAP) gene expression in colorectal carcinoma cells

Konsavage, W. M., Kyler, S. L., Rennoll, S. A., Jin, G. & Yochum, G. S., Apr 6 2012, In : Journal of Biological Chemistry. 287, 15, p. 11730-11739 10 p.

Research output: Contribution to journalArticle

Catenins
Gene expression
Colorectal Neoplasms
Cells
Gene Expression
58 Citations (Scopus)

Wnt signaling stimulates transcriptional outcome of the hedgehog pathway by stabilizing GLI1 mRNA

Noubissi, F. K., Goswami, S., Sanek, N. A., Kawakami, K., Minamoto, T., Moser, A., Grinblat, Y. & Spiegelman, V. S., Nov 15 2009, In : Cancer Research. 69, 22, p. 8572-8578 7 p.

Research output: Contribution to journalArticle

Wnt Signaling Pathway
Catenins
Messenger RNA
RNA-Binding Proteins
Embryonic Development
34 Citations (Scopus)

Wounding prior to challenge substantially improves infectivity of cottontail rabbit papillomavirus and allows for standardization of infection

Cladel, N. M., Hu, J., Balogh, K., Mejia, A. & Christensen, N. D., Mar 1 2008, In : Journal of Virological Methods. 148, 1-2, p. 34-39 6 p.

Research output: Contribution to journalArticle

Cottontail rabbit papillomavirus
Infection
Papillomavirus Infections
Animal Models
Research Personnel
9 Citations (Scopus)
Benzo(a)pyrene
Xenobiotics
Cytochrome P-450 Enzyme System
Microsomes
Diptera
119 Citations (Scopus)

Xenobiotic metabolomics: Major impact on the metabolome

Johnson, C. H., Patterson, A. D., Idle, J. R. & Gonzalez, F. J., Jan 20 2012, In : Annual Review of Pharmacology and Toxicology. 52, p. 37-56 20 p.

Research output: Contribution to journalArticle

Metabolomics
Metabolome
Xenobiotics
Metabolism
Environmental Pollutants
9 Citations (Scopus)

Xenobiotic microsomal epoxide hydrolase: 5′ sequence of the human gene

Wilson, N. M. & Omiecinski, C. J., Aug 14 1989, In : BBA - Gene Structure and Expression. 1008, 3, p. 357-358 2 p.

Research output: Contribution to journalArticle

Epoxide Hydrolases
Xenobiotics
Genes
Rats
Complementary DNA
52 Citations (Scopus)

XIAP inhibition and generation of reactive oxygen species enhances TRAIL sensitivity in inflammatory breast cancer cells

Allensworth, J. L., Aird, K. M., Aldrich, A. J., Batinic-Haberle, I. & Devi, G. R., Jul 1 2012, In : Molecular cancer therapeutics. 11, 7, p. 1518-1527 10 p.

Research output: Contribution to journalArticle

X-Linked Inhibitor of Apoptosis Protein
Inflammatory Breast Neoplasms
Reactive Oxygen Species
Apoptosis
Caspases
45 Citations (Scopus)

X-linked inhibitor of apoptosis protein inhibits apoptosis in inflammatory breast cancer cells with acquired resistance to an ErbB1/2 tyrosine kinase inhibitor

Aird, K. M., Ghanayem, R. B., Peplinski, S., Lyerly, H. K. & Devi, G. R., May 1 2010, In : Molecular cancer therapeutics. 9, 5, p. 1432-1442 11 p.

Research output: Contribution to journalArticle

TYK2 Kinase
X-Linked Inhibitor of Apoptosis Protein
Inflammatory Breast Neoplasms
Apoptosis
Breast Neoplasms
3 Citations (Scopus)

X-ray crystal structure of a reiterative transcription complex reveals an atypical RNA extension pathway

Murakami, K. S., Shin, Y., Turnbough, C. L. & Molodtsov, V., Aug 1 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 31, p. 8211-8216 6 p.

Research output: Contribution to journalArticle

X-Rays
RNA
Thermus thermophilus
Enzymes
DNA-Directed RNA Polymerases
114 Citations (Scopus)

X-ray crystal structure of escherichia coli RNA polymerase σ70 holoenzyme

Murakami, K. S., Mar 29 2013, In : Journal of Biological Chemistry. 288, 13, p. 9126-9134 9 p.

Research output: Contribution to journalArticle

Holoenzymes
DNA-Directed RNA Polymerases
Escherichia coli
Crystal structure
X-Rays