Research Output 1963 2019

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2017
8 Citations (Scopus)

The joint effect of air pollution exposure and copy number variation on risk for autism

Kim, D., Volk, H., Girirajan, S., Pendergrass, S., Hall, M., Verma, S. S., Schmidt, R. J., Hansen, R. L., Ghosh, D., Ludena-Rodriguez, Y., Kim, K., Ritchie, M. D., Hertz-Picciotto, I. & Selleck, S. B., Sep 1 2017, In : Autism Research. 10, 9, p. 1470-1480 11 p.

Research output: Contribution to journalArticle

Air Pollution
Autistic Disorder
Ozone
Air Pollutants
Environmental Exposure
7 Citations (Scopus)

The Microbial Ecosystem Distinguishes Chronically Diseased Tissue from Adjacent Tissue in the Sigmoid Colon of Chronic, Recurrent Diverticulitis Patients

Schieffer, K. M., Sabey, K., Wright, J. R., Toole, D. R., Drucker, R., Tokarev, V., Harris, L. R., Deiling, S., Eshelman, M. A., Hegarty, J. P., Yochum, G., Koltun, W., Lamendella, R. & Stewart, D., Dec 1 2017, In : Scientific reports. 7, 1, 8467.

Research output: Contribution to journalArticle

Diverticulitis
Sigmoid Colon
Ecosystem
Sigmoid Diseases
Diverticulum
65 Citations (Scopus)

The mitochondrial Na+/Ca2+ exchanger is essential for Ca2+ homeostasis and viability

Luongo, T. S., Lambert, J. P., Gross, P., Nwokedi, M., Lombardi, A. A., Santhanam, S., Carpenter, A. C., Kolmetzky, D., Gao, E., Van Berlo, J. H., Tsai, E. J., Molkentin, J. D., Chen, X., Madesh, M., Houser, S. R. & Elrod, J. W., May 4 2017, In : Nature. 545, 7652, p. 93-97 5 p.

Research output: Contribution to journalArticle

Homeostasis
Cell Death
Heart Failure
Gene Transfer Techniques
Tamoxifen
7 Citations (Scopus)

The mouse papillomavirus infection model

Hu, J., Cladel, N. M., Budgeon, L. R., Balogh, K. K. & Christensen, N., Sep 1 2017, In : Viruses. 9, 9, 246.

Research output: Contribution to journalArticle

Papillomavirus Infections
Laboratory Animals
Immunocompromised Host
Infection
Disease Progression
4 Citations (Scopus)

The RNA-Binding Site of Poliovirus 3C Protein Doubles as a Phosphoinositide-Binding Domain

Shengjuler, D., Chan, Y. M., Sun, S., Moustafa, I., Li, Z. L., Gohara, D. W., Buck, M., Cremer, P. S., Boehr, D. D. & Cameron, C. E., Dec 5 2017, In : Structure. 25, 12, p. 1875-1886.e7

Research output: Contribution to journalArticle

Phosphatidylinositol Phosphates
Poliovirus
Phosphatidylinositols
Binding Sites
RNA
9 Citations (Scopus)

The role of UVR and Vitamin D on T cells and inflammatory bowel disease

Bora, S. & Cantorna, M. T-A., Jan 1 2017, In : Photochemical and Photobiological Sciences. 16, 3, p. 347-353 7 p.

Research output: Contribution to journalArticle

calciferol
T-cells
Vitamin D
Ultraviolet radiation
ultraviolet radiation
8 Citations (Scopus)

TRIM21 is a novel regulator of Par-4 in colon and pancreatic cancer cells

Nguyen, J. Q. & Irby, R., Jan 2 2017, In : Cancer Biology and Therapy. 18, 1, p. 16-25 10 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Colonic Neoplasms
Cisplatin
prostate apoptosis response-4 protein
Neoplasms
5 Citations (Scopus)

Triphosphate reorientation of the incoming nucleotide as a fidelity checkpoint in viral RNA-dependent RNA Polymerases

Yang, X., Liu, X., Musser, D. M., Moustafa, I., Arnold, J. J., Cameron, C. E. & Boehr, D. D., Mar 3 2017, In : Journal of Biological Chemistry. 292, 9, p. 3810-3826 17 p.

Research output: Contribution to journalArticle

RNA Replicase
Viral RNA
Nucleotides
Structural dynamics
Poliovirus
28 Citations (Scopus)

Tumour-derived Interleukin 35 promotes pancreatic ductal adenocarcinoma cell extravasation and metastasis by inducing ICAM1 expression

Huang, C., Li, N., Li, Z., Chang, A., Chen, Y., Zhao, T., Li, Y., Wang, X., Zhang, W., Wang, Z., Luo, L., Shi, J., Yang, S., Ren, H. & Hao, J., Jan 1 2017, In : Nature communications. 8, 14035.

Research output: Contribution to journalArticle

interleukins
Interleukins
metastasis
Tumors
Adenocarcinoma
5 Citations (Scopus)

UGGT1 enhances enterovirus 71 pathogenicity by promoting viral RNA synthesis and viral replication

Huang, P. N., Jheng, J. R., Arnold, J. J., Wang, J. R., Cameron, C. E. & Shih, S. R., May 1 2017, In : PLoS Pathogens. 13, 5, e1006375.

Research output: Contribution to journalArticle

Enterovirus
Viral RNA
Unfolded Protein Response
Virulence
RNA Virus Infections
9 Citations (Scopus)

Unexpected sequences and structures of mtDNA required for efficient transcription from the first heavy-strand promoter

Uchida, A., Murugesapillai, D., Kastner, M., Wang, Y., Lodeiro, M. F., Prabhakar, S., Oliver, G. V., Arnold, J. J., Maher, L. J., Williams, M. C. & Cameron, C. E., Jul 26 2017, In : eLife. 6, e27283.

Research output: Contribution to journalArticle

Transcription
Mitochondrial DNA
Tail
Chemical activation
Transcription Initiation Site
5 Citations (Scopus)

UVC radiation as an effective disinfectant method to inactivate human papillomaviruses

Meyers, C., Milici, J. & Robison, R., Oct 1 2017, In : PloS one. 12, 10, e0187377.

Research output: Contribution to journalArticle

Papillomaviridae
Disinfectants
disinfectants
ultraviolet radiation
Disinfection
12 Citations (Scopus)

VE-Cadherin Disassembly and Cell Contractility in the Endothelium are Necessary for Barrier Disruption Induced by Tumor Cells

Aragon-Sanabria, V., Pohler, S. E., Eswar, V. J., Bierowski, M., Gomez, E. W. & Dong, C., Apr 10 2017, In : Scientific reports. 7, 45835.

Research output: Contribution to journalArticle

Endothelium
Endothelial Cells
Neoplasms
Adherens Junctions
Cell Movement
4 Citations (Scopus)

Viral DNA replication orientation and hnrnps regulate transcription of the human papillomavirus 18 late promoter

Wang, X., Liu, H., Ge, H., Ajiro, M., Sharma, N. R., Meyers, C., Morozov, P., Tuschl, T., Klar, A., Court, D. & Zhenga, Z. M., May 1 2017, In : mBio. 8, 3, e00713-17.

Research output: Contribution to journalArticle

Human papillomavirus 18
Viral DNA
DNA Replication
Heterogeneous-Nuclear Ribonucleoproteins
Keratinocytes
14 Citations (Scopus)

Western diet induces colonic nitrergic myenteric neuropathy and dysmotility in mice via saturated fatty acid- and lipopolysaccharide-induced TLR4 signalling

Reichardt, F., Chassaing, B., Nezami, B. G., Li, G., Tabatabavakili, S., Mwangi, S., Uppal, K., Liang, B., Kumar, M. V., Jones, D., Gewirtz, A. T. & Srinivasan, S., Mar 1 2017, In : Journal of Physiology. 595, 5, p. 1831-1846 16 p.

Research output: Contribution to journalArticle

Toll-Like Receptor 4
Lipopolysaccharides
Fatty Acids
Dysbiosis
Nonesterified Fatty Acids
2 Citations (Scopus)

X-ray crystal structure of a reiterative transcription complex reveals an atypical RNA extension pathway

Murakami, K. S., Shin, Y., Turnbough, C. L. & Molodtsov, V., Aug 1 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 31, p. 8211-8216 6 p.

Research output: Contribution to journalArticle

X-Rays
RNA
Thermus thermophilus
Enzymes
DNA-Directed RNA Polymerases
2016
21 Citations (Scopus)
epigallocatechin
colitis
Colitis
Weight Loss
Digestion
22 Citations (Scopus)

Acid ceramidase is upregulated in AML and represents a novel therapeutic target

Tan, S. F., Liu, X., Fox, T. E., Barth, B. M., Sharma, A., Turner, S. D., Awwad, A., Dewey, A., Doi, K., Spitzer, B., Shah, M. V., Morad, S. A. F., Desai, D., Amin, S., Zhu, J., Liao, J. J., Yun, J., Kester, M., Claxton, D., Wang, H-G. & 5 others, Cabot, M. C., Schuchman, E. H., Levine, R. L., Feith, D. J. & Loughran, T. P., Jan 1 2016, In : Oncotarget. 7, 50, p. 83208-83222 15 p.

Research output: Contribution to journalArticle

Acid Ceramidase
Acute Myeloid Leukemia
Ceramides
Sphingolipids
Myeloid Cells
14 Citations (Scopus)

Acoustofluidic Transfer of Inflammatory Cells from Human Sputum Samples

Li, S., Ren, L., Huang, P. H., Yao, X., Cuento, R. A., McCoy, J. P., Cameron, C. E., Levine, S. J. & Huang, T. J., Jun 7 2016, In : Analytical Chemistry. 88, 11, p. 5655-5661 7 p.

Research output: Contribution to journalArticle

Dithiothreitol
Surface waves
Buffers
Acoustic waves
Liquefaction
2 Citations (Scopus)

Activation of the Constitutive Androstane Receptor by Monophthalates

Laurenzana, E. M., Coslo, D. M., Vigilar, M. V., Roman, A. M. & Omiecinski, C. J., Oct 17 2016, In : Chemical research in toxicology. 29, 10, p. 1651-1661 11 p.

Research output: Contribution to journalArticle

Chemical activation
Cytoplasmic and Nuclear Receptors
Plasticizers
Metabolites
constitutive androstane receptor

Altered co-translational processing plays a role in huntington’s pathogenesis-A hypothesis

Nissley, D. A. & O'Brien, Jr., E. P., Jul 6 2016, In : Frontiers in Molecular Neuroscience. 9, JUL, 54.

Research output: Contribution to journalArticle

Huntington Disease
Proline
Age of Onset
Codon
Neurodegenerative Diseases
8 Citations (Scopus)

Altered Expression of the Transcription Factor Forkhead Box A1 (FOXA1) Is Associated With Poor Prognosis in Urothelial Carcinoma of the Upper Urinary Tract

Raman, J., Warrick, J., Caruso, C., Yang, Z., Shuman, L., Bruggeman, R. D., Shariat, S., Karam, J. A., Wood, C., Weizer, A. Z., Remzi, M., Haitel, A., Bensalah, K., Rioux-Leclerq, N., Bolenz, C., Roscigno, M., Krabbe, L. M., Kapur, P., Lotan, Y., Margulis, V. & 1 others, Degraff, D., Aug 1 2016, In : Urology. 94, p. 314.e1-314.e7

Research output: Contribution to journalArticle

Forkhead Transcription Factors
Urinary Tract
Carcinoma
Carcinoma in Situ
Confidence Intervals
3 Citations (Scopus)

AMPKγ3 is dispensable for skeletal muscle hypertrophy induced by functional overload

Riedl, I., Osler, M. E., Björnholm, M., Egan, B., Nader, G. A., Chibalin, A. V. & Zierath, J. R., Jan 1 2016, In : American Journal of Physiology - Endocrinology and Metabolism. 310, 6, p. E461-E472

Research output: Contribution to journalArticle

Hypertrophy
Skeletal Muscle
Protein Isoforms
Sirolimus
Muscles
1 Citation (Scopus)

Analysis and purification of mouse intestinal dendritic cell and macrophage subsets by flow cytometry

Koscsó, B. & Bogunovic, M., Jan 1 2016, In : Current Protocols in Immunology. 2016, p. 14.39.1-14.39.14

Research output: Contribution to journalArticle

Dendritic Cells
Flow Cytometry
Macrophages
Small Intestine
Suspensions
7 Citations (Scopus)

A novel AhR ligand, 2AI, protects the retina from environmental stress

Gutierrez, M. A., Davis, S. S., Rosko, A., Nguyen, S. M., Mitchell, K. P., Mateen, S., Neves, J., Garcia, T. Y., Mooney, S., Perdew, G. H., Hubbard, T. D., Lamba, D. A. & Ramanathan, A., Jul 1 2016, In : Scientific reports. 6, 29025.

Research output: Contribution to journalArticle

Aryl Hydrocarbon Receptors
Retina
Retinal Degeneration
Epithelial Cells
Blindness
7 Citations (Scopus)
Docosahexaenoic Acids
Cells
Breast Neoplasms
Cell Line
Acids
5 Citations (Scopus)

Antimicrobial fungal endophytes from the botanical medicine goldenseal (Hydrastis canadensis)

Egan, J. M., Kaur, A., Raja, H. A., Kellogg, J., Oberlies, N. H. & Cech, N. B., Sep 1 2016, In : Phytochemistry Letters. 17, p. 219-225 7 p.

Research output: Contribution to journalArticle

Hydrastis
Hydrastis canadensis
Endophytes
endophytes
Medicine
7 Citations (Scopus)

Antimicrobial prescribing patterns in a large tertiary hospital in Shanghai, China

Wang, Y. Y., Du, P., Huang, F., Li, D. J., Gu, J., Shen, F. M. & Jiang, Y. Y., Dec 1 2016, In : International Journal of Antimicrobial Agents. 48, 6, p. 666-673 8 p.

Research output: Contribution to journalArticle

Tertiary Care Centers
Prescriptions
China
Anti-Bacterial Agents
Health Expenditures
10 Citations (Scopus)

Antioxidant Drug Tempol Promotes Functional Metabolic Changes in the Gut Microbiota

Cai, J., Zhang, L., Jones, R. A., Correll, J. B., Hatzakis, E., Smith, P. B., Gonzalez, F. J. & Patterson, A. D., Feb 5 2016, In : Journal of Proteome Research. 15, 2, p. 563-571 9 p.

Research output: Contribution to journalArticle

Antioxidants
Metabolomics
Pharmaceutical Preparations
Liver
Weight Gain
10 Citations (Scopus)

A Role for MYC in Lithium-Stimulated Repair of the Colonic Epithelium After DSS-Induced Damage in Mice

Raup-Konsavage, W. M., Cooper, T. & Yochum, G., Feb 1 2016, In : Digestive Diseases and Sciences. 61, 2, p. 410-422 13 p.

Research output: Contribution to journalArticle

Dextran Sulfate
Lithium
Regeneration
Colitis
Epithelium
8 Citations (Scopus)

Arsenic trioxide plus PX-478 achieves effective treatment in pancreatic ductal adenocarcinoma

Lang, M., Wang, X., Wang, H., Dong, J., Lan, C., Hao, J., Huang, C., Li, X., Yu, M., Yang, Y., Yang, S. & Ren, H., Aug 10 2016, In : Cancer Letters. 378, 2, p. 87-96 10 p.

Research output: Contribution to journalArticle

Adenocarcinoma
Hypoxia-Inducible Factor 1
Reactive Oxygen Species
Pancreatic Neoplasms
Apoptosis

A sacrificial process for fabrication of biodegradable polymer membranes with submicron thickness

Beardslee, L. A., Stolwijk, J., Khaladj, D. A., Trebak, M., Halman, J., Torrejon, K. Y., Niamsiri, N. & Bergkvist, M., Aug 1 2016, In : Journal of Biomedical Materials Research - Part B Applied Biomaterials. 104, 6, p. 1192-1201 10 p.

Research output: Contribution to journalArticle

Biodegradable polymers
Membranes
Fabrication
Polycaprolactone
Polymers
4 Citations (Scopus)

A selenium containing inhibitor for the treatment of hepatocellular cancer

Tagaram, H. R. S., Desai, D., Li, G., Liu, D., Rountree, C. B., Gowda, K., Berg, A., Amin, S., Staveley-O’carroll, K. F. & Kimchi, E. T., Mar 24 2016, In : Pharmaceuticals. 9, 2, 18.

Research output: Contribution to journalArticle

Liver Neoplasms
Selenium
Hepatocellular Carcinoma
Phosphatidylinositol 3-Kinases
Neoplasms
9 Citations (Scopus)

A standardized chemically modified Curcuma longa extract modulates IRAK-MAPK signaling in inflammation and potentiates cytotoxicity

Rana, M., Maurya, P., Reddy, S. S., Singh, V., Ahmad, H., Dwivedi, A. K., Dikshit, M. & Barthwal, M. K., Jul 25 2016, In : Frontiers in Pharmacology. 7, JUL, 223.

Research output: Contribution to journalArticle

Open Access
Curcuma
HL-60 Cells
Interleukin-1
Anti-Inflammatory Agents
Inflammation
2 Citations (Scopus)

Binding by TRBP-dsRBD2 Does Not Induce Bending of Double-Stranded RNA

Acevedo, R., Evans, D., Penrod, K. A. & Showalter, S. A., Jun 21 2016, In : Biophysical journal. 110, 12, p. 2610-2617 8 p.

Research output: Contribution to journalArticle

Double-Stranded RNA
Nucleic Acids
RNA
Biological Phenomena
Calorimetry
10 Citations (Scopus)

Biochemical and genetic analysis of the role of the viral polymerase in enterovirus recombination

Woodman, A., Arnold, J. J., Cameron, C. E. & Evans, D. J., Aug 19 2016, In : Nucleic acids research. 44, 14, p. 6883-6895 13 p.

Research output: Contribution to journalArticle

Enterovirus
Genetic Recombination
Molecular Biology
Poliovirus
RNA Replicase
43 Citations (Scopus)

Biochemometrics for Natural Products Research: Comparison of Data Analysis Approaches and Application to Identification of Bioactive Compounds

Kellogg, J., Todd, D. A., Egan, J. M., Raja, H. A., Oberlies, N. H., Kvalheim, O. M. & Cech, N. B., Feb 26 2016, In : Journal of Natural Products. 79, 2, p. 376-386 11 p.

Research output: Contribution to journalArticle

Fractionation
Biological Products
Biological Assay
Bioassay
Alternaria
6 Citations (Scopus)

Bioinformatic analysis of microRNA networks following the activation of the constitutive androstane receptor (CAR) in mouse liver

Hao, R., Su, S., Wan, Y., Shen, F., Niu, B., Coslo, D. M., Albert, I., Han, X. & Omiecinski, C. J., Sep 1 2016, In : Biochimica et Biophysica Acta - Gene Regulatory Mechanisms. 1859, 9, p. 1228-1237 10 p.

Research output: Contribution to journalArticle

Bioinformatics
Computational Biology
MicroRNAs
Liver
Chemical activation
14 Citations (Scopus)

Blockade of MK2 is protective in inflammation-associated colorectal cancer development

Ray, A. L., Castillo, E. F., Morris, K. T., Nofchissey, R. A., Weston, L. L., Samedi, V. G., Hanson, J. A., Gaestel, M., Pinchuk, I. & Beswick, E. J., Feb 1 2016, In : International Journal of Cancer. 138, 3, p. 770-775 6 p.

Research output: Contribution to journalArticle

Open Access
Protein Kinases
Colorectal Neoplasms
Inflammation
Colonic Neoplasms
Macrophages
9 Citations (Scopus)

Bolaamphiphile-based nanocomplex delivery of phosphorothioate gapmer antisense oligonucleotides as a treatment for Clostridium difficile

Hegarty, J. P., Krzeminski, J., Sharma, A., Guzman-Villanueva, D., Weissig, V. & Stewart, D., Aug 1 2016, In : International Journal of Nanomedicine. 11, p. 3607-3619 13 p.

Research output: Contribution to journalArticle

Clostridium
Clostridium difficile
Antisense Oligonucleotides
Oligonucleotides
Dequalinium

Breast cancer metastasis to the thyroid gland

Goldenberg, M., Warrick, J., Russo, M. & Bann, D. V., Oct 1 2016, In : Ear, nose, & throat journal. 95, 10-11, p. 444-451 8 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Broad cross-protection is induced in preclinical models by a human papillomavirus vaccine composed of L1/L2 chimeric virus-like particles

Boxus, M., Fochesato, M., Miseur, A., Mertens, E., Dendouga, N., Brendle, S., Balogh, K. K., Christensen, N. & Giannini, S. L., Jan 1 2016, In : Journal of virology. 90, 14, p. 6314-6325 12 p.

Research output: Contribution to journalArticle

Cross Protection
Papillomavirus Vaccines
virus-like particles
Papillomaviridae
Virion
4 Citations (Scopus)

C60-SIMS imaging of nanoparticles within mammalian cells

Bloom, A. N., Tian, H. & Winograd, N., Jun 1 2016, In : Biointerphases. 11, 2, p. 1-7 7 p.

Research output: Contribution to journalArticle

Secondary Ion Mass Spectrometry
Secondary ion mass spectrometry
Nanoparticles
secondary ion mass spectrometry
Cells
20 Citations (Scopus)

Calcium signaling is dispensable for receptor regulation of endothelial barrier function

Stolwijk, J. A., Zhang, X., Gueguinou, M., Zhang, W., Matrougui, K., Renken, C. & Trebak, M., Oct 28 2016, In : Journal of Biological Chemistry. 291, 44, p. 22894-22912 19 p.

Research output: Contribution to journalArticle

Calcium Signaling
G-Protein-Coupled Receptors
Calcium
Thrombin
Cell Membrane
29 Citations (Scopus)

CD90+ stromal cells are the major source of IL-6, which supports cancer stem-like cells and inflammation in colorectal cancer

Huynh, P. T., Beswick, E. J., Coronado, Y. A., Johnson, P., O'Connell, M. R., Watts, T., Singh, P., Qiu, S., Morris, K., Powell, D. W. & Pinchuk, I., Apr 15 2016, In : International Journal of Cancer. 138, 8, p. 1971-1981 11 p.

Research output: Contribution to journalArticle

Neoplastic Stem Cells
Stromal Cells
Colorectal Neoplasms
Interleukin-6
Inflammation
9 Citations (Scopus)

Cell-cell contact and matrix adhesion promote αSMA expression during TGFβ1-induced epithelial-myofibroblast transition via Notch and MRTF-A

O'Connor, J. W., Mistry, K., Detweiler, D., Wang, C. & Gomez, E. W., May 19 2016, In : Scientific reports. 6, 26226.

Research output: Contribution to journalArticle

Cell-Matrix Junctions
Myofibroblasts
Smooth Muscle
Actins
Transcription Factors
27 Citations (Scopus)

Cell-free hepatitis B virus capsid assembly dependent on the core protein C-terminal domain and regulated by phosphorylation

Ludgate, L., Liu, K., Luckenbaugh, L., Streck, N., Eng, S., Voitenleitner, C., Delaney, W. E. & Hu, J., Jun 1 2016, In : Journal of virology. 90, 12, p. 5830-5844 15 p.

Research output: Contribution to journalArticle

Virus Assembly
capsid
Hepatitis B virus
Capsid
Protein C
11 Citations (Scopus)

Cell type- and tissue context-dependent nuclear distribution of human Ago2

Sharma, N. R., Wang, X., Majerciak, V., Ajiro, M., Kruhlak, M., Meyers, C. & Zheng, Z. M., Jan 29 2016, In : Journal of Biological Chemistry. 291, 5, p. 2302-2309 8 p.

Research output: Contribution to journalArticle

Argonaute Proteins
Tissue
Nuclear Proteins
Proteins
Keratinocytes
20 Citations (Scopus)

Characterization of human translesion DNA synthesis across a UV-induced DNA lesion

Hedglin, M., Pandey, B. & Benkovic, S., Oct 22 2016, In : eLife. 5, OCTOBER2016, e19788.

Research output: Contribution to journalArticle

DNA
Proliferating Cell Nuclear Antigen
DNA-Directed DNA Polymerase
Ubiquitination
Post Translational Protein Processing

Chromatin rules

Li, Y. & Huang, S., Feb 1 2016, In : Stem Cell Investigation. 2016, FEB, 4.

Research output: Contribution to journalArticle