Research Output 1963 2020

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Review article
2020

Heart regeneration with human pluripotent stem cells: Prospects and challenges

Jiang, Y. & Lian, X. L., Mar 2020, In : Bioactive Materials. 5, 1, p. 74-81 8 p.

Research output: Contribution to journalReview article

Open Access
Pluripotent Stem Cells
Stem cells
Regeneration
Myocardial Infarction
Endothelial cells

The gut microbiome: an orchestrator of xenobiotic metabolism

Collins, S. L. & Patterson, A. D., Jan 2020, In : Acta Pharmaceutica Sinica B. 10, 1, p. 19-32 14 p.

Research output: Contribution to journalReview article

Open Access
Microbiota
Xenobiotics
Pharmacokinetics
Enterohepatic Circulation
Multiple Drug Resistance
2019

Activation of the Ah Receptor Modulates Gastrointestinal Homeostasis and the Intestinal Microbiome

Muku, G. E., Murray, I. A. & Perdew, G. H., Oct 1 2019, In : Current Pharmacology Reports. 5, 5, p. 319-331 13 p.

Research output: Contribution to journalReview article

Aryl Hydrocarbon Receptors
Homeostasis
Chemical activation
Ligands
Gastrointestinal Microbiome
7 Citations (Scopus)

Aldehyde dehydrogenase in regulatory T-cell development, immunity and cancer

Bazewicz, C. G., Dinavahi, S. S., Schell, T. D. & Robertson, G. P., Jan 2019, In : Immunology. 156, 1, p. 47-55 9 p.

Research output: Contribution to journalReview article

Aldehyde Dehydrogenase
Regulatory T-Lymphocytes
Immunity
Neoplasms
Immune Tolerance
1 Citation (Scopus)

Aligning the Paradoxical Role of Vitamin D in Gastrointestinal Immunity

Cantorna, M. T-A., Rogers, C. J. & Arora, J., Jul 1 2019, In : Trends in Endocrinology and Metabolism. 30, 7, p. 459-466 8 p.

Research output: Contribution to journalReview article

Vitamin D
Immunity
Inflammatory Bowel Diseases
Infection
T-Lymphocytes
1 Citation (Scopus)

A review of analytical platforms for accurate bile acid measurement

Dutta, M., Cai, J., Gui, W. & Patterson, A. D., Jul 19 2019, In : Analytical and Bioanalytical Chemistry. 411, 19, p. 4541-4549 9 p.

Research output: Contribution to journalReview article

Bile Acids and Salts
Clinical laboratories
Intestinal Diseases
Molecules
Liquid chromatography
1 Citation (Scopus)

Asymmetry in icosahedral viruses

Goetschius, D. J., Parrish, C. R. & Hafenstein, S., Jun 1 2019, In : Current Opinion in Virology. 36, p. 67-73 7 p.

Research output: Contribution to journalReview article

Leviviridae
Genome
Viruses
Picornaviridae
Capsid Proteins

A trip down memory lane with Retrovirology

Benkirane, M., Berkhout, B., Borrow, P., Fassati, A., Fujii, M., Garcia-Martinez, J. V., Margolis, D., Nijhuis, M., Parent, L., Strebel, K., Venter, F., Kirchhoff, F., Lever, A., Ross, S. & Mak, J., Aug 21 2019, In : Retrovirology. 16, 1, 22.

Research output: Contribution to journalReview article

Open Access
17 Citations (Scopus)

Calcium signalling in T cells

Trebak, M. & Kinet, J. P., Mar 1 2019, In : Nature Reviews Immunology. 19, 3, p. 154-169 16 p.

Research output: Contribution to journalReview article

Calcium Signaling
T-Lymphocytes
Immunity
Cell Membrane
Lymphocytes
2 Citations (Scopus)

Cancer and the dopamine D2 receptor: A pharmacological perspective

Weissenrieder, J. S., Neighbors, J. D., Mailman, R. B. & Hohl, R. J., Jan 1 2019, In : Journal of Pharmacology and Experimental Therapeutics. 370, 1, p. 111-126 16 p.

Research output: Contribution to journalReview article

Dopamine D2 Receptors
Pharmacology
Neoplasms
Ligands
Drug Therapy

Epo receptor marks the spot

Paulson, R. F., Jan 1 2019, In : Blood. 134, 5, p. 413-414 2 p.

Research output: Contribution to journalReview article

Open Access
Macrophages
Erythropoietin Receptors
Erythroblasts
Blood
4 Citations (Scopus)

Interplay Between the Host, the Human Microbiome, and Drug Metabolism

Nichols, R. G., Peters, J. M. & Patterson, A. D., Jun 11 2019, In : Human genomics. 13, 1, 1 p.

Research output: Contribution to journalReview article

Open Access
Microbiota
Pharmaceutical Preparations
Carboxylic Ester Hydrolases
Bacterial Vaginosis
Prebiotics
1 Citation (Scopus)

Jumonji C demethylases in cellular senescence

Leon, K. E. & Aird, K. M., Jan 1 2019, In : Genes. 10, 1, 33.

Research output: Contribution to journalReview article

Cell Aging
Histones
Gene Expression
Enzyme Induction
Cell Cycle Checkpoints
1 Citation (Scopus)

Mechanochemistry in Translation

Leininger, S. E., Narayan, K., Deutsch, C. & O'Brien, E. P., Nov 26 2019, In : Biochemistry. 58, 47, p. 4657-4666 10 p.

Research output: Contribution to journalReview article

Peptidyl Transferases
Protein folding
Protein Folding
Ribosomes
Tunnels

MEF-2 isoforms' (A-D) roles in development and tumorigenesis

Madugula, K., Mulherkar, R., Khan, Z. K., Chigbu, D. G. I., Patel, D., Harhaj, E. W. & Jain, P., Apr 12 2019, In : Oncotarget. 10, 28, p. 2755-2787 33 p.

Research output: Contribution to journalReview article

Open Access
MEF2 Transcription Factors
Protein Isoforms
Carcinogenesis
Transcription Factors
Histone Deacetylases
Urinary Bladder Neoplasms
Drug Therapy
Muscles
Neoplasms
3 Citations (Scopus)

ORAI channels in cellular remodeling of cardiorespiratory disease

Johnson, M. & Trebak, M., May 2019, In : Cell Calcium. 79, p. 1-10 10 p.

Research output: Contribution to journalReview article

Ion Channels
Pulmonary Hypertension
Chronic Obstructive Pulmonary Disease
Smooth Muscle
Atherosclerosis
4 Citations (Scopus)
Open Access
regulators
cellulose
mechanics
cell walls
cell wall components
1 Citation (Scopus)

Revisiting Hepatitis B virus: Challenges of curative therapies

Hu, J., Protzer, U. & Siddiqui, A., Oct 1 2019, In : Journal of virology. 93, 20, e01032-19.

Research output: Contribution to journalReview article

Hepatitis B virus
circular DNA
Circular DNA
therapeutics
Antiviral Agents

Secretion of empty or complete hepatitis B virions: Envelopment of empty capsids versus mature nucleocapsids

Liu, K. & Hu, J., Feb 1 2019, In : Future Virology. 14, 2, p. 95-105 11 p.

Research output: Contribution to journalReview article

Nucleocapsid
Capsid
Hepatitis B
Virion
RNA
3 Citations (Scopus)

Selection and characterization of botanical natural products for research studies: A NaPDI center recommended approach

Kellogg, J. J., Paine, M. F., McCune, J. S., Oberlies, N. H. & Cech, N. B., Aug 2019, In : Natural Product Reports. 36, 8, p. 1196-1221 26 p.

Research output: Contribution to journalReview article

Open Access
Biological Products
Research
Research Personnel
Industry
Dietary supplements
Chromatin
Transcription Factors
Histone Code
DNA-Binding Proteins
Histones
2 Citations (Scopus)
Cottontail rabbit papillomavirus
Papillomaviridae
rabbits
Sylvilagus floridanus
Rabbits
Open Access
Central Nervous System Viral Diseases
T-Lymphocytes
Virus Diseases
Brain
T-Lymphocyte Subsets
5 Citations (Scopus)
Mucosal Immunity
Vitamin A
Vitamin D
Homeostasis
T-cells
2018
3 Citations (Scopus)

An Introduction to the Structure and Function of the Catalytic Core Enzyme of Escherichia coli RNA Polymerase

Sutherland, C. & Murakami, K. S., Aug 1 2018, In : EcoSal Plus. 8, 1

Research output: Contribution to journalReview article

DNA-Directed RNA Polymerases
Catalytic Domain
Escherichia coli
Enzymes
Research Personnel
20 Citations (Scopus)

Crosslink between calcium and sodium signalling

Verkhratsky, A., Trebak, M., Perocchi, F., Khananshvili, D. & Sekler, I., Feb 1 2018, In : Experimental Physiology. 103, 2, p. 157-169 13 p.

Research output: Contribution to journalReview article

Calcium Signaling
Transient Receptor Potential Channels
Sodium
Ions
Synaptic Transmission
3 Citations (Scopus)

Cross-talk between Wnt and Hh signaling pathways in the pathology of basal cell carcinoma

Noubissi, F. K., Yedjou, C. G., Spiegelman, V. S. & Tchounwou, P. B., Jul 9 2018, In : International journal of environmental research and public health. 15, 7, 1442.

Research output: Contribution to journalReview article

Wnt Signaling Pathway
Hedgehogs
Basal Cell Carcinoma
Pathology
Insulin-Like Growth Factor Binding Protein 2
2 Citations (Scopus)
oncogenes
DNA-Directed DNA Polymerase
DNA Replication
Oncogenes
DNA
2 Citations (Scopus)
obesity
Docosahexaenoic Acids
breast
constrictions
Obesity
7 Citations (Scopus)

Engineered control of enzyme structural dynamics and function

Boehr, D. D., D'Amico, R. N. & O'Rourke, K. F., Apr 2018, In : Protein Science. 27, 4, p. 825-838 14 p.

Research output: Contribution to journalReview article

Structural dynamics
Enzymes
Catalytic Domain
Protein Engineering
Post Translational Protein Processing
8 Citations (Scopus)

Insights into macrophage heterogeneity and cytokine-induced neuroinflammation in major depressive disorder

Dey, A. & Giblin, P. A. H., Sep 2018, In : Pharmaceuticals. 11, 3, 64.

Research output: Contribution to journalReview article

Major Depressive Disorder
Macrophages
Cytokines
Depression
Psychiatry
9 Citations (Scopus)

Mechanisms of erythrocyte development and regeneration: Implications for regenerative medicine and beyond

Bresnick, E. H., Hewitt, K. J., Mehta, C., Keles, S., Paulson, R. F. & Johnson, K. D., Jan 2018, In : Development (Cambridge). 145, 1, dev151423.

Research output: Contribution to journalReview article

Regenerative Medicine
Regeneration
Erythrocytes
Hematopoietic Stem Cells
Oxygen
14 Citations (Scopus)

Mitochondrial Ca2+ signaling

Pathak, T. & Trebak, M., Dec 2018, In : Pharmacology and Therapeutics. 192, p. 112-123 12 p.

Research output: Contribution to journalReview article

Homeostasis
Mitochondrial Proteins
Energy Metabolism
Membrane Proteins
Calcium
1 Citation (Scopus)

Molecular Regulation of Carcinogenesis: Friend and Foe

Patterson, A. D., Gonzalez, F. J., Perdew, G. H. & Peters, J. M., Oct 1 2018, In : Toxicological Sciences. 165, 2, p. 277-283 7 p.

Research output: Contribution to journalReview article

Cell signaling
T-Cell Antigen Receptor
Medicine
Explosions
Tumors
13 Citations (Scopus)

Molecular regulation of MCU: Implications in physiology and disease

Nemani, N., Santhanam, S. & Madesh, M., Sep 1 2018, In : Cell Calcium. 74, p. 86-93 8 p.

Research output: Contribution to journalReview article

Divalent Cations
Mitochondrial Membranes
Membrane Potentials
Energy Metabolism
Mitochondria
6 Citations (Scopus)

NF-κB signaling mechanisms in HTLV-1-induced adult T-cell leukemia/lymphoma

Harhaj, E. W. & Giam, C. Z., Sep 2018, In : FEBS Journal. 285, 18, p. 3324-3336 13 p.

Research output: Contribution to journalReview article

Deltaretrovirus
Adult T Cell Leukemia Lymphoma
T-cells
Viruses
Taxation
10 Citations (Scopus)

Non-equilibrium coupling of protein structure and function to translation–elongation kinetics

Sharma, A. K. & O'Brien, E. P., Apr 2018, In : Current Opinion in Structural Biology. 49, p. 94-103 10 p.

Research output: Contribution to journalReview article

Proteins
Natural Science Disciplines
Messenger RNA
Protein Folding
Physics
3 Citations (Scopus)

Pathophysiology of diverticular disease

Schieffer, K. M., Kline, B. P., Yochum, G. & Koltun, W., Jul 3 2018, In : Expert Review of Gastroenterology and Hepatology. 12, 7, p. 683-692 10 p.

Research output: Contribution to journalReview article

Diverticulitis
Microbiota
Diverticulum
Genetic Predisposition to Disease
PubMed
1 Citation (Scopus)

Schweinfurthins: Lipid Modulators with Promising Anticancer Activity

Koubek, E. J., Weissenrieder, J. S., Neighbors, J. D. & Hohl, R. J., Aug 2018, In : Lipids. 53, 8, p. 767-784 18 p.

Research output: Contribution to journalReview article

Modulators
Lipids
Neoplasms
Cells
trans-Golgi Network
11 Citations (Scopus)

Selenium and selenoproteins in gut inflammation—A review

Nettleford, S. K. & Prabhu, K. S., Mar 1 2018, In : Antioxidants. 7, 3, 36.

Research output: Contribution to journalReview article

Selenoproteins
Selenium
Inflammatory Bowel Diseases
Peroxisome Proliferator-Activated Receptors
Inflammation

The Evolution of Carcinogenesis

Peters, J. M. & Gonzalez, F. J., Oct 1 2018, In : Toxicological Sciences. 165, 2, p. 272-276 5 p.

Research output: Contribution to journalReview article

Metabolism
Carcinogenesis
6 Citations (Scopus)

The intricate role of selenium and selenoproteins in erythropoiesis

Liao, C., Carlson, B. A., Paulson, R. & Prabhu, K. S., Nov 1 2018, In : Free Radical Biology and Medicine. 127, p. 165-171 7 p.

Research output: Contribution to journalReview article

Selenoproteins
Erythropoiesis
Selenium
Anemia
Macrophages
1 Citation (Scopus)

The Mevalonate Pathway and Terpenes: a Diversity of Chemopreventatives

Neighbors, J., Apr 1 2018, In : Current Pharmacology Reports. 4, 2, p. 157-169 13 p.

Research output: Contribution to journalReview article

Mevalonic Acid
Terpenes
Chemoprevention
Biological Products
Carbon
26 Citations (Scopus)

The PPARα-dependent rodent liver tumor response is not relevant to humans: addressing misconceptions

Corton, J. C., Peters, J. M. & Klaunig, J. E., Jan 1 2018, In : Archives of Toxicology. 92, 1, p. 83-119 37 p.

Research output: Contribution to journalReview article

Peroxisome Proliferator-Activated Receptors
Liver
Tumors
Rodentia
Neoplasms
2017
2 Citations (Scopus)

Analysis of Gene-Gene Interactions

Cole, B. S., Hall, M. A., Urbanowicz, R. J., Gilbert-Diamond, D. & Moore, J. H., Oct 2017, In : Current protocols in human genetics. 95, 1, p. 1.14.1-1.14.10

Research output: Contribution to journalReview article

Genes
Disease Susceptibility
Meta-Analysis
Research
Machine Learning
79 Citations (Scopus)

A New View into the Regulation of Purine Metabolism: The Purinosome

Pedley, A. M. & Benkovic, S. J., Feb 1 2017, In : Trends in Biochemical Sciences. 42, 2, p. 141-154 14 p.

Research output: Contribution to journalReview article

Metabolism
Multienzyme Complexes
Mitochondria
Enzymes
Metabolites
11 Citations (Scopus)

Carcinogenesis of the oral cavity: Environmental causes and potential prevention by black raspberry

El-Bayoumy, K., Chen, K. M., Zhang, S. M., Sun, Y. W., Amin, S., Stoner, G. & Guttenplan, J. B., Jan 1 2017, In : Chemical research in toxicology. 30, 1, p. 126-144 19 p.

Research output: Contribution to journalReview article

Mouth Neoplasms
Mouth
Environmental Carcinogens
Carcinogenesis
Animal Models
12 Citations (Scopus)

Clinical significance of histologic variants of bladder cancer

Warrick, J. I., Oct 1 2017, In : JNCCN Journal of the National Comprehensive Cancer Network. 15, 10, p. 1268-1274 7 p.

Research output: Contribution to journalReview article

Urinary Bladder Neoplasms
Carcinoma
Mortality
Drug Therapy
Observer Variation
59 Citations (Scopus)

Complete and incomplete hepatitis B virus particles: Formation, function, and application

Hu, J. & Liu, K., Mar 21 2017, In : Viruses. 9, 3, 56.

Research output: Contribution to journalReview article

Defective Viruses
Hepatitis B virus
Virion
Capsid
Genome