Research Output 1963 2020

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Review article
1980
85 Citations (Scopus)

On the mechanism of action of folate- and biopterin-requiring enzymes.

Benkovic, S., Jan 1 1980, In : Annual Review of Biochemistry. 49, p. 227-251 25 p.

Research output: Contribution to journalReview article

Methylenetetrahydrofolate Dehydrogenase (NADP)
Formates
Glycine Hydroxymethyltransferase
Biopterin
Pteridines
1988
13 Citations (Scopus)

The dynamics of DNA polymerase-catalyzed reactions.

Mizrahi, V. & Benkovic, S., Jan 1 1988, In : Advances in Enzymology and Related Areas of Molecular Biology. 61, p. 437-457 21 p.

Research output: Contribution to journalReview article

Exonucleases
DNA-Directed DNA Polymerase
Binding Sites
Thermodynamics
Kinetics
1989
9 Citations (Scopus)

Transforming growth factor-beta and suppression of carcinogenesis.

Sporn, M. B., Roberts, A. B., Wakefield, L. M., Glick, A. B. & Danielpour, D., Jan 1 1989, In : Princess Takamatsu symposia. 20, p. 259-266 8 p.

Research output: Contribution to journalReview article

Transforming Growth Factor beta
Carcinogenesis
Tretinoin
Epithelium
Epithelial Cells
1991

Catalytic antibodies.

Benkovic, S., 1991, In : Harvey lectures. 87, p. 115-128 14 p.

Research output: Contribution to journalReview article

Catalytic Antibodies
Anilides
Antibody Binding Sites
Molecular structure
Hydrolysis
443 Citations (Scopus)

Form, function, and use of retroviral Gag proteins

Wills, J. & Craven, R., Jan 1 1991, In : AIDS. 5, 6, p. 639-654 16 p.

Research output: Contribution to journalReview article

gag Gene Products
Nucleocapsid Proteins
Myristic Acid
Capsid Proteins
Retroviridae
85 Citations (Scopus)

Multiple forms of TGF-beta: distinct promoters and differential expression.

Roberts, A. B., Kim, S. J., Noma, T., Glick, A. B., Lafyatis, R., Lechleider, R., Jakowlew, S. B., Geiser, A., O'Reilly, M. A. & Danielpour, D., Jan 1 1991, In : Ciba Foundation symposium. 157, p. 7-15 9 p.

Research output: Contribution to journalReview article

Transforming Growth Factor beta3
Transforming Growth Factor beta2
Transforming Growth Factor beta1
Transforming Growth Factor beta
Protein Isoforms
33 Citations (Scopus)
India
Public Health
Siblings
Mortality
Survival
1992
7 Citations (Scopus)

Alterations in the biology and biochemistry of keratinocytes induced by the ras oncogene.

Yuspa, S. H., Punnonen, K., Lee, E., Hennings, H., Strickland, J. E., Cheng, C., Glick, A. B. & Dlugosz, A., 1992, In : Progress in Clinical and Biological Research. 376, p. 103-115 13 p.

Research output: Contribution to journalReview article

Experimental Neoplasms
ras Genes
Keratinocytes
Cell Division
Biochemistry
150 Citations (Scopus)

Diverse transcriptional functions of the multisubunit eukaryotic TFIID complex

Pugh, B. F. & Tjian, R., Jan 1 1992, In : Journal of Biological Chemistry. 267, 2, p. 679-682 4 p.

Research output: Contribution to journalReview article

Genetic Transcription
Transcription Factor TFIID
RNA Polymerase III
TATA Box
Eukaryotic Cells
1993
37 Citations (Scopus)

Catalytic antibodies: Mechanistic and practical considerations

Stewart, J. D. & Benkovic, S., Dec 1 1993, In : Chemical Society Reviews. 22, 4, p. 213-219 7 p.

Research output: Contribution to journalReview article

Catalytic Antibodies
59 Citations (Scopus)

Cigarette smoking and adenocarcinoma of the lung: The relevance of nicotine-derived N-nitrosamines

Hoffmann, D., Rivenson, A., Murphy, S. E., Chung, F. L., Amin, S. & Hecht, S. S., Jan 1 1993, In : Journal of Smoking-Related Disorders. 4, 3, p. 165-189 25 p.

Research output: Contribution to journalReview article

Nitrosamines
Nicotine
Tobacco
Tobacco Products
Smoking
3 Citations (Scopus)

The in vitro analysis of biochemical changes relevant to skin carcinogenesis.

Yuspa, S. H., Punnonen, K., Lee, E., Hennings, H., Strickland, J., Cheng, C., Glick, A. B. & Dlugosz, A., Jan 1 1993, In : Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer. 128, p. 299-308 10 p.

Research output: Contribution to journalReview article

Neoplastic Cell Transformation
Cultured Tumor Cells
Skin Neoplasms
Keratinocytes
Epidermis
1994
82 Citations (Scopus)

Evaluation of chemopreventive agents against breast cancer and proposed strategies for future clinical intervention trials

Ei-Bayoumy, K., Nov 1 1994, In : Carcinogenesis. 15, 11, p. 2395-2420 26 p.

Research output: Contribution to journalReview article

Clinical Trials
Breast Neoplasms
Complex Mixtures
Chemoprevention
Laboratory Animals
66 Citations (Scopus)

In vitro systems for the study and propagation of human papillomaviruses

Meyers, C. & Laimins, L. A., Jan 1 1994, In : Current topics in microbiology and immunology. 186, p. 199-215 17 p.

Research output: Contribution to journalReview article

Virus Cultivation
Heterologous Transplantation
Virus Replication
Nude Mice
Skin
11 Citations (Scopus)

Tobacco-specific nitrosamines.

Hecht, S. S., Peterson, L. A. & Spratt, T., Jan 1 1994, In : IARC scientific publications. 125, p. 91-106 16 p.

Research output: Contribution to journalReview article

Toxic Plants
Nitrosamines
DNA Adducts
Carcinogens
Tobacco
1995
9 Citations (Scopus)

The role of growth factors in mouse skin tumor promotion and premalignant progression.

Yuspa, S. H., Hennings, H., Dlugosz, A., Tennenbaum, T. & Glick, A. B., Jan 1 1995, In : Progress in clinical and biological research. 391, p. 39-48 10 p.

Research output: Contribution to journalReview article

Fibroblast Growth Factor 10
Growth Substances
Precancerous Conditions
Fibroblast Growth Factor 7
Transforming Growth Factor alpha
28 Citations (Scopus)

Wound infection following trauma and burn injuries.

Klein, D. G., Fritsch, D. E. & Amin, S., Dec 1 1995, In : Critical care nursing clinics of North America. 7, 4, p. 627-642 16 p.

Research output: Contribution to journalReview article

Wound Infection
Wounds and Injuries
Wound Healing
Anti-Bacterial Agents
Infection
1996
26 Citations (Scopus)

Milk-borne prolactin and neonatal development.

Ellis, L. A., Mastro, A. M. & Picciano, M. F., Jan 1 1996, In : Journal of Mammary Gland Biology and Neoplasia. 1, 3, p. 259-269 11 p.

Research output: Contribution to journalReview article

Prolactin
Milk
Food
Neurosecretory Systems
Child Development
29 Citations (Scopus)

Synthesis of tobacco-specific N-nitrosamines and their metabolites and results of related bioassays

Amin, S., Desai, D., Hecht, S. S. & Hoffmann, D., Jan 1 1996, In : Critical Reviews in Toxicology. 26, 2, p. 139-147 9 p.

Research output: Contribution to journalReview article

N'-nitrosonornicotine
Nitrosamines
Tobacco
Bioassay
Metabolites
1997
312 Citations (Scopus)

NMR solution structures of stereoisomeric covalent polycyclic aromatic carcinogen-DNA adducts: Principles, patterns, and diversity

Geacintov, N. E., Cosman, M., Hingerty, B. E., Amin, S., Broyde, S. & Patel, D. J., Feb 1 1997, In : Chemical research in toxicology. 10, 2, p. 111-146 36 p.

Research output: Contribution to journalReview article

DNA Adducts
Intercalation
Carcinogens
Amines
styrene oxide
14 Citations (Scopus)

Organoselenium compounds: A novel class of cancer chemopreventive agents

El-Bayoumy, K., Jan 1 1997, In : Drugs of the Future. 22, 5, p. 539-545 7 p.

Research output: Contribution to journalReview article

Organoselenium Compounds
Neoplasms
77 Citations (Scopus)

The Cbl protooncogene product: From an enigmatic oncogene to center stage of signal transduction

Miyake, S., Lupher, M. L., Andoniou, C. E., Lill, N., Ota, S., Douillard, P., Rao, N. & Band, H., Jan 1 1997, In : Critical Reviews in Oncogenesis. 8, 2-3, p. 189-218 30 p.

Research output: Contribution to journalReview article

Oncogenes
Protein-Tyrosine Kinases
Phosphotyrosine
Signal Transduction
RING Finger Domains
23 Citations (Scopus)

Why are hepadnaviruses DNA and not RNA viruses?

Seeger, C. & Hu, J., Nov 1 1997, In : Trends in Microbiology. 5, 11, p. 447-450 4 p.

Research output: Contribution to journalReview article

Hepadnaviridae
Genetic Transcription
Nucleocapsid
RNA Viruses
RNA-Directed DNA Polymerase
1998
72 Citations (Scopus)

Antioxidants and Lipid Oxidation in Foods - A Critical Appraisal

Adegoke, G. O., Kumar, M. V., Gopala Krishna, A. G., Varadaraj, M. C., Sambaiah, K. & Lokesh, B. R., Jul 1 1998, In : Journal of Food Science and Technology. 35, 4, p. 283-298 16 p.

Research output: Contribution to journalReview article

lipid peroxidation
Antioxidants
Lipids
antioxidants
Food
63 Citations (Scopus)

Physiological and pathophysiological regulation of cytochrome P450

Morgan, E. T., Sewer, M. B., Iber, H., Gonzalez, F. J., Lee, Y. H., Tukey, R. H., Okino, S., Vu, T., Chen, Y. H., Sidhu, J. S. & Omiecinski, C. J., Dec 1 1998, In : Drug Metabolism and Disposition. 26, 12, p. 1232-1240 9 p.

Research output: Contribution to journalReview article

Gene Knockout Techniques
San Francisco
Reporter Genes
Knockout Mice
Cytochrome P-450 Enzyme System
1999
7 Citations (Scopus)

Chromatin structure and nuclear remodeling

Johansen, K. M., Johansen, J., Jin, Y., Walker, D. L., Wang, D. & Wang, Y., Jan 1 1999, In : Critical Reviews in Eukaryotic Gene Expression. 9, 3-4, p. 267-277 11 p.

Research output: Contribution to journalReview article

Chromatin
Cell Cycle
Prometaphase
Polytene Chromosomes
Spindle Apparatus
139 Citations (Scopus)

Concise review of the cytochrome P450s and their roles in toxicology

Omiecinski, C. J., Remmel, R. P. & Hosagrahara, V. P., May 25 1999, In : Toxicological Sciences. 48, 2, p. 151-156 6 p.

Research output: Contribution to journalReview article

Xenobiotics
Cytochromes
Toxicology
Cytochrome P-450 Enzyme System
15 Citations (Scopus)

Symposium overview: The role of genetic polymorphism and repair deficiencies in environmental disease

Hulla, J. E., Miller, M. S., Taylor, J. A., Hein, D. W., Furlong, C. E., Omiecinski, C. J. & Kunkel, T. A., Jan 1 1999, In : Toxicological Sciences. 47, 2, p. 135-143 9 p.

Research output: Contribution to journalReview article

Genetic Polymorphisms
Polymorphism
Repair
Enzymes
Epoxide Hydrolases
97 Citations (Scopus)
Ornithine Decarboxylase
Adenosylmethionine Decarboxylase
Polyamines
Enzymes
Open Reading Frames
2000
254 Citations (Scopus)

Chemical basis for enzyme catalysis

Bruice, T. C. & Benkovic, S. J., May 30 2000, In : Biochemistry. 39, 21, p. 6267-6274 8 p.

Research output: Contribution to journalReview article

Catalysis
Enzymes
144 Citations (Scopus)

Control of gene expression through regulation of the TATA-binding protein

Pugh, B. F., Sep 5 2000, In : Gene. 255, 1, p. 1-14 14 p.

Research output: Contribution to journalReview article

TATA-Box Binding Protein
Gene Expression Regulation
Holoenzymes
RNA Polymerase II
DNA
1 Citation (Scopus)

Evaluation of benzo[c]chrysene dihydrodiols in the morphological cell transformation of mouse embryo fibroblast C3H10T1/2CL8 cells

Nesnow, S., Davis, C., Desai, D. & Amin, S., Jan 1 2000, In : Polycyclic Aromatic Compounds. 21, 1-4, p. 203-213 11 p.

Research output: Contribution to journalReview article

Fibroblasts
Chemical activation
benzo(c)chrysene
trans-1,2-dihydro-1,2-naphthalenediol
45 Citations (Scopus)

Evolution of protein function by domain swapping

Ostermeier, M. & Benkovic, S., Oct 26 2000, In : Advances in Protein Chemistry. 55, p. 29-78 50 p.

Research output: Contribution to journalReview article

Proteins
17 Citations (Scopus)

Homology-independent protein engineering

Lutz, S. & Benkovic, S. J., Aug 1 2000, In : Current Opinion in Biotechnology. 11, 4, p. 319-324 6 p.

Research output: Contribution to journalReview article

Protein Engineering
Proteins
Homologous Recombination
561 Citations (Scopus)

Role of Src expression and activation in human cancer

Irby, R. & Yeatman, T. J., Nov 20 2000, In : Oncogene. 19, 49, p. 5636-5642 7 p.

Research output: Contribution to journalReview article

src Genes
Neoplasms
Retroviridae
Drug Discovery
Growth and Development
2001
3 Citations (Scopus)

Biology of the PPAR family of receptors

Vanden Heuvel, J. P. & Peters, J. M., 2001, In : Comments on Toxicology. 7, 3, p. 233-257 25 p.

Research output: Contribution to journalReview article

Peroxisome Proliferator-Activated Receptors
Homeostasis
Peroxisome Proliferators
Lipids
Leukotrienes
11 Citations (Scopus)

Comparative roles of phospholipase A2 isoforms in cardiovascular pathophysiology.

McHowat, J. & Creer, M., Jan 1 2001, In : Cardiovascular Toxicology. 1, 4, p. 253-265 13 p.

Research output: Contribution to journalReview article

Plasmalogens
Ventricular Remodeling
Enzyme Activation
Phospholipases A
Phospholipases A2
23 Citations (Scopus)

Dynamic protein interactions in the bacteriophage T4 replisome

Trakselis, M. A., Mayer, M. U., Ishmael, F. T., Roccasecca, R. M. & Benkovic, S. J., Sep 1 2001, In : Trends in Biochemical Sciences. 26, 9, p. 566-572 7 p.

Research output: Contribution to journalReview article

Bacteriophage T4
Bacteriophages
Holoenzymes
Proteins
Structural Models
11 Citations (Scopus)

EBV regulates c-MYC, apoptosis, and tumorigenicity in Burkitt's lymphoma

Ruf, I. K., Rhyne, P. W., Yang, H., Borza, C. M., Hutt-Fletcher, L. M., Cleveland, J. L. & Sample, J., Jan 1 2001, In : Current Topics in Microbiology and Immunology. 258, p. 153-160 8 p.

Research output: Contribution to journalReview article

Proto-Oncogene Proteins c-bcl-2
Epstein-Barr Virus Nuclear Antigens
Proto-Oncogene Proteins c-myc
Virus Latency
Cultured Tumor Cells
15 Citations (Scopus)

Immunity to polyoma virus infection and tumorigenesis

Moser, J. M. & Lukacher, A., Jan 1 2001, In : Viral Immunology. 14, 3, p. 199-216 18 p.

Research output: Contribution to journalReview article

Polyomavirus
Virus Diseases
Immunity
Carcinogenesis
T-Lymphocytes
24 Citations (Scopus)

Intricacies in ATP-dependent clamp loading: Variations across replication systems

Trakselis, M. A. & Benkovic, S., Jan 1 2001, In : Structure. 9, 11, p. 999-1004 6 p.

Research output: Contribution to journalReview article

Adenosine Triphosphate
Holoenzymes
DNA Replication
Proteins
Genome
30 Citations (Scopus)

Multiorgan sensitivity to anticarcinogenesis by the organoselenium 1,4-phenylenebis(methylene)selenocyanate

El-Bayoumy, K., Rao, C. V. & Reddy, B. S., Jan 1 2001, In : Nutrition and cancer. 40, 1, p. 18-27 10 p.

Research output: Contribution to journalReview article

Organoselenium Compounds
Poisons
Chemoprevention
Selenium
Colon
248 Citations (Scopus)

Replisome-mediated DNA replication

Benkovic, S. J., Valentine, A. M. & Salinas, F., Jul 30 2001, In : Annual Review of Biochemistry. 70, p. 181-208 28 p.

Research output: Contribution to journalReview article

DNA Replication
DNA Primase
DNA
DNA Helicases
Accessories

Structural bases of RNA polymerase functions

Murakami, K. & Ishihama, A., Jan 1 2001, In : Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme. 46, 11 Suppl, p. 1608-1617 10 p.

Research output: Contribution to journalReview article

Protein Conformation
DNA-Directed RNA Polymerases
Structure-Activity Relationship
Transcription Factors
Binding Sites
509 Citations (Scopus)

The less harmful cigarette: A controversial issue. A tribute to Ernst L. Wynder

Hoffmann, D., Hoffmann, I. & El-Bayoumy, K., Jul 31 2001, In : Chemical research in toxicology. 14, 7, p. 767-790 24 p.

Research output: Contribution to journalReview article

Tobacco Products
Smoke
Smoking
Public health
Nicotine
75 Citations (Scopus)

The mechanism of action of ribavirin: Lethal mutagenesis of RNA virus genomes mediated by the viral RNA-dependent RNA polymerase

Cameron, C. E. & Castro, C., Jan 1 2001, In : Current Opinion in Infectious Diseases. 14, 6, p. 757-764 8 p.

Research output: Contribution to journalReview article

RNA Replicase
Ribavirin
RNA Viruses
Viral RNA
Mutagenesis
302 Citations (Scopus)

The protective role of selenium on genetic damage and on cancer

El-Bayoumy, K., Apr 18 2001, In : Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 475, 1-2, p. 123-139 17 p.

Research output: Contribution to journalReview article

Selenium
Selenium Compounds
Recommended Dietary Allowances
Neoplasms
Genomic Instability
641 Citations (Scopus)

Vitamin D: Its role and uses in immunology

Deluca, H. F. & Cantorna, M. T., Dec 22 2001, In : FASEB Journal. 15, 14, p. 2579-2585 7 p.

Research output: Contribution to journalReview article

Immunology
Allergy and Immunology
Vitamin D
T-cells
Hormones
2002
146 Citations (Scopus)
Cell signaling
Aryl Hydrocarbon Receptors
Genes
Immunophilins
Casein Kinase II
48 Citations (Scopus)

An integrated view of the roles and mechanisms of heat shock protein gp96-peptide complex in eliciting immune response.

Li, Z., Dai, J., Zheng, H., Liu, B. & Caudill, M., Mar 1 2002, In : Frontiers in bioscience : a journal and virtual library. 7, p. d731-751

Research output: Contribution to journalReview article

Antigen-Presenting Cells
Heat-Shock Proteins
Peptides
Cross-Priming
T-cells