Research Output 1963 2020

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Review article

Activation of the Ah Receptor Modulates Gastrointestinal Homeostasis and the Intestinal Microbiome

Muku, G. E., Murray, I. A. & Perdew, G. H., Oct 1 2019, In : Current Pharmacology Reports. 5, 5, p. 319-331 13 p.

Research output: Contribution to journalReview article

Aryl Hydrocarbon Receptors
Homeostasis
Chemical activation
Ligands
Gastrointestinal Microbiome
146 Citations (Scopus)
Cell signaling
Aryl Hydrocarbon Receptors
Genes
Immunophilins
Casein Kinase II
6 Citations (Scopus)

Aldehyde dehydrogenase in regulatory T-cell development, immunity and cancer

Bazewicz, C. G., Dinavahi, S. S., Schell, T. D. & Robertson, G. P., Jan 2019, In : Immunology. 156, 1, p. 47-55 9 p.

Research output: Contribution to journalReview article

Aldehyde Dehydrogenase
Regulatory T-Lymphocytes
Immunity
Neoplasms
Immune Tolerance
1 Citation (Scopus)

Aligning the Paradoxical Role of Vitamin D in Gastrointestinal Immunity

Cantorna, M. T-A., Rogers, C. J. & Arora, J., Jul 1 2019, In : Trends in Endocrinology and Metabolism. 30, 7, p. 459-466 8 p.

Research output: Contribution to journalReview article

Vitamin D
Immunity
Inflammatory Bowel Diseases
Infection
T-Lymphocytes
443 Citations (Scopus)

Allosteric regulation and catalysis emerge via a common route

Goodey, N. M. & Benkovic, S. J., Aug 2008, In : Nature Chemical Biology. 4, 8, p. 474-482 9 p.

Research output: Contribution to journalReview article

Allosteric Regulation
Catalysis
Allosteric Site
Protein Engineering
Computer Communication Networks
7 Citations (Scopus)

Alterations in the biology and biochemistry of keratinocytes induced by the ras oncogene.

Yuspa, S. H., Punnonen, K., Lee, E., Hennings, H., Strickland, J. E., Cheng, C., Glick, A. B. & Dlugosz, A., 1992, In : Progress in Clinical and Biological Research. 376, p. 103-115 13 p.

Research output: Contribution to journalReview article

Experimental Neoplasms
ras Genes
Keratinocytes
Cell Division
Biochemistry
19 Citations (Scopus)

Analyses of RAS Regulation of Eye Development in Drosophila melanogaster

Firth, L. C., Li, W., Zhang, H. & Baker, N. E., Jan 1 2006, In : Methods in enzymology. 407, p. 711-721 11 p.

Research output: Contribution to journalReview article

Drosophila melanogaster
Cells
Receptor Protein-Tyrosine Kinases
ras Genes
Cellular Structures
2 Citations (Scopus)

Analysis of Gene-Gene Interactions

Cole, B. S., Hall, M. A., Urbanowicz, R. J., Gilbert-Diamond, D. & Moore, J. H., Oct 2017, In : Current protocols in human genetics. 95, 1, p. 1.14.1-1.14.10

Research output: Contribution to journalReview article

Genes
Disease Susceptibility
Meta-Analysis
Research
Machine Learning
7 Citations (Scopus)

Analysis of the DNA translocation and unwinding activities of T4 phage helicases

Perumal, S. K., Raney, K. D. & Benkovic, S., Jul 1 2010, In : Methods. 51, 3, p. 277-288 12 p.

Research output: Contribution to journalReview article

Bacteriophage T4
Bacteriophages
DNA
RNA
Biological Phenomena
79 Citations (Scopus)

A New View into the Regulation of Purine Metabolism: The Purinosome

Pedley, A. M. & Benkovic, S. J., Feb 1 2017, In : Trends in Biochemical Sciences. 42, 2, p. 141-154 14 p.

Research output: Contribution to journalReview article

Metabolism
Multienzyme Complexes
Mitochondria
Enzymes
Metabolites
48 Citations (Scopus)

An integrated view of the roles and mechanisms of heat shock protein gp96-peptide complex in eliciting immune response.

Li, Z., Dai, J., Zheng, H., Liu, B. & Caudill, M., Mar 1 2002, In : Frontiers in bioscience : a journal and virtual library. 7, p. d731-751

Research output: Contribution to journalReview article

Antigen-Presenting Cells
Heat-Shock Proteins
Peptides
Cross-Priming
T-cells
64 Citations (Scopus)

An Intestinal Microbiota–Farnesoid X Receptor Axis Modulates Metabolic Disease

Gonzalez, F. J., Jiang, C. & Patterson, A. D., Nov 1 2016, In : Gastroenterology. 151, 5, p. 845-859 15 p.

Research output: Contribution to journalReview article

choloylglycine hydrolase
Metabolic Diseases
Ceramides
High Fat Diet
Microbiota
3 Citations (Scopus)

An Introduction to the Structure and Function of the Catalytic Core Enzyme of Escherichia coli RNA Polymerase

Sutherland, C. & Murakami, K. S., Aug 1 2018, In : EcoSal Plus. 8, 1

Research output: Contribution to journalReview article

DNA-Directed RNA Polymerases
Catalytic Domain
Escherichia coli
Enzymes
Research Personnel
72 Citations (Scopus)

Antioxidants and Lipid Oxidation in Foods - A Critical Appraisal

Adegoke, G. O., Kumar, M. V., Gopala Krishna, A. G., Varadaraj, M. C., Sambaiah, K. & Lokesh, B. R., Jul 1 1998, In : Journal of Food Science and Technology. 35, 4, p. 283-298 16 p.

Research output: Contribution to journalReview article

lipid peroxidation
Antioxidants
Lipids
antioxidants
Food
799 Citations (Scopus)

A perspective on enzyme catalysis

Benkovic, S. J. & Hammes-Schiffer, S., Aug 29 2003, In : Science. 301, 5637, p. 1196-1202 7 p.

Research output: Contribution to journalReview article

Catalysis
Enzymes
Protein Engineering
Tetrahydrofolate Dehydrogenase
Proteins
199 Citations (Scopus)
Selenium Compounds
Chemoprevention
Apoptosis
Drug Therapy
Selenium
17 Citations (Scopus)

Application of live-cell RNA imaging techniques to the study of retroviral RNA trafficking

Bann, D. V. & Parent, L. J., Jun 15 2012, In : Viruses. 4, 6, p. 963-979 17 p.

Research output: Contribution to journalReview article

RNA
Retroviridae
Virion
Viral Structural Proteins
Cell Nucleus Active Transport
28 Citations (Scopus)

Archaeal RNA polymerase

Hirata, A. & Murakami, K. S., Dec 1 2009, In : Current Opinion in Structural Biology. 19, 6, p. 724-731 8 p.

Research output: Contribution to journalReview article

Archaeal RNA
DNA-Directed RNA Polymerases
Eukaryota
General Transcription Factors
Archaea
1 Citation (Scopus)

A review of analytical platforms for accurate bile acid measurement

Dutta, M., Cai, J., Gui, W. & Patterson, A. D., Jul 19 2019, In : Analytical and Bioanalytical Chemistry. 411, 19, p. 4541-4549 9 p.

Research output: Contribution to journalReview article

Bile Acids and Salts
Clinical laboratories
Intestinal Diseases
Molecules
Liquid chromatography
23 Citations (Scopus)

A risk for non-sexual transmission of human papillomavirus?

Ryndock, E. J. & Meyers, C., Oct 1 2014, In : Expert Review of Anti-Infective Therapy. 12, 10, p. 1165-1170 6 p.

Research output: Contribution to journalReview article

Papillomaviridae
Vertical Infectious Disease Transmission
Fomites
Papillomavirus Infections
Disinfectants
10 Citations (Scopus)

A role for PPARβ/δ in tumor stroma and tumorigenesis

Müller, R., Kömhoff, M., Peters, J. M. & Müller-Brüsselbach, S., Jun 23 2008, In : PPAR Research. 534294.

Research output: Contribution to journalReview article

Peroxisome Proliferator-Activated Receptors
Carcinogenesis
Neoplasms
Fatty Acids
Vascular Tissue Neoplasms
271 Citations (Scopus)

Aryl hydrocarbon receptor ligands in cancer: Friend and foe

Murray, I. A., Patterson, A. D. & Perdew, G. H., Nov 24 2014, In : Nature Reviews Cancer. 14, 12, p. 801-814 14 p.

Research output: Contribution to journalReview article

Aryl Hydrocarbon Receptors
Ligands
Neoplasms
Carcinogenesis
Dioxins

Asymmetry in icosahedral viruses

Goetschius, D. J., Parrish, C. R. & Hafenstein, S., Jun 1 2019, In : Current Opinion in Virology. 36, p. 67-73 7 p.

Research output: Contribution to journalReview article

Leviviridae
Genome
Viruses
Picornaviridae
Capsid Proteins
59 Citations (Scopus)

A three-dimensional osteogenic tissue model for the study of metastatic tumor cell interactions with bone

Mastro, A. M. & Vogler, E. A., May 15 2009, In : Cancer Research. 69, 10, p. 4097-4100 4 p.

Research output: Contribution to journalReview article

Osteoblasts
Cell Communication
Bone and Bones
Bioreactors
Osteocytes

A trip down memory lane with Retrovirology

Benkirane, M., Berkhout, B., Borrow, P., Fassati, A., Fujii, M., Garcia-Martinez, J. V., Margolis, D., Nijhuis, M., Parent, L., Strebel, K., Venter, F., Kirchhoff, F., Lever, A., Ross, S. & Mak, J., Aug 21 2019, In : Retrovirology. 16, 1, 22.

Research output: Contribution to journalReview article

Open Access
345 Citations (Scopus)

Bacterial RNA polymerases: The wholo story

Murakami, K. S. & Darst, S. A., Feb 1 2003, In : Current Opinion in Structural Biology. 13, 1, p. 31-39 9 p.

Research output: Contribution to journalReview article

Bacterial RNA
DNA-Directed RNA Polymerases
Holoenzymes
16 Citations (Scopus)

Beyond plasma membrane targeting: Role of the MA domain of Gag in retroviral genome encapsidation

Parent, L. J. & Gudleski, N., Jul 22 2011, In : Journal of Molecular Biology. 410, 4, p. 553-564 12 p.

Research output: Contribution to journalReview article

gag Gene Products
Product Packaging
Cell Membrane
Genome
Virus Assembly
462 Citations (Scopus)

Biological Properties of Curcumin-Cellular and Molecular Mechanisms of Action

Joe, B., Kumar, M. V. & Lokesh, B. R., May 12 2004, In : Critical Reviews in Food Science and Nutrition. 44, 2, p. 97-111 15 p.

Research output: Contribution to journalReview article

Curcumin
curcumin
Antioxidants
mechanism of action
Methane
3 Citations (Scopus)

Biology of the PPAR family of receptors

Vanden Heuvel, J. P. & Peters, J. M., 2001, In : Comments on Toxicology. 7, 3, p. 233-257 25 p.

Research output: Contribution to journalReview article

Peroxisome Proliferator-Activated Receptors
Homeostasis
Peroxisome Proliferators
Lipids
Leukotrienes
141 Citations (Scopus)

Boron-containing inhibitors of synthetases

Baker, S. J., Tomsho, J. W. & Benkovic, S., Aug 1 2011, In : Chemical Society Reviews. 40, 8, p. 4279-4285 7 p.

Research output: Contribution to journalReview article

Boronic Acids
Boron
Ligases
Pharmaceutical Preparations
Nucleophiles
18 Citations (Scopus)

BRCA1 and BRCA2 mutations in the ovarian cancer population across race and ethnicity: Special reference to Asia

Shanmughapriya, S., Nachiappan, V. & Natarajaseenivasan, K., Jan 1 2013, In : Oncology (Switzerland). 84, 4, p. 226-232 7 p.

Research output: Contribution to journalReview article

Ovarian Neoplasms
Mutation
Population
Iceland
Aptitude
51 Citations (Scopus)

Breast cancer cells induce osteoblast apoptosis: A possible contributor to bone degradation

Mastro, A. M., Gay, C. V., Welch, D. R., Donahue, H. J., Jewell, J., Mercer, R., DiGirolamo, D., Chislock, E. M. & Guttridge, K., Dec 1 2004, In : Journal of cellular biochemistry. 91, 2, p. 265-276 12 p.

Research output: Contribution to journalReview article

Osteoblasts
Bone
Cells
Apoptosis
Breast Neoplasms
14 Citations (Scopus)

Breast cancer metastasis to bone: Evolving models and research challenges

Welch, D. R., Harms, J. F., Mastro, A. M., Gay, C. V. & Donahue, H. J., Mar 1 2003, In : Journal of Musculoskeletal Neuronal Interactions. 3, 1, p. 30-38 9 p.

Research output: Contribution to journalReview article

Osteonectin
Parathyroid Hormone-Related Protein
Osteolysis
Osteopontin
Osteoclasts
128 Citations (Scopus)

Breast cancer metastasis to the bone: Mechanisms of bone loss

Chen, Y. C., Sosnoski, D. M. & Mastro, A. M., Dec 16 2010, In : Breast Cancer Research. 12, 6, 215.

Research output: Contribution to journalReview article

Osteoclasts
Osteoblasts
Breast Neoplasms
Neoplasm Metastasis
Bone and Bones
16 Citations (Scopus)

Calcium signalling in T cells

Trebak, M. & Kinet, J. P., Mar 1 2019, In : Nature Reviews Immunology. 19, 3, p. 154-169 16 p.

Research output: Contribution to journalReview article

Calcium Signaling
T-Lymphocytes
Immunity
Cell Membrane
Lymphocytes
2 Citations (Scopus)

Cancer and the dopamine D2 receptor: A pharmacological perspective

Weissenrieder, J. S., Neighbors, J. D., Mailman, R. B. & Hohl, R. J., Jan 1 2019, In : Journal of Pharmacology and Experimental Therapeutics. 370, 1, p. 111-126 16 p.

Research output: Contribution to journalReview article

Dopamine D2 Receptors
Pharmacology
Neoplasms
Ligands
Drug Therapy
14 Citations (Scopus)

Canonical transient receptor potential channels in disease: targets for novel drug therapy?

Trebak, M., Oct 1 2006, In : Drug Discovery Today. 11, 19-20, p. 924-930 7 p.

Research output: Contribution to journalReview article

Transient Receptor Potential Channels
Drosophila
Drug Therapy
Photoreceptor Cells
Type C Phospholipases
11 Citations (Scopus)

Carcinogenesis of the oral cavity: Environmental causes and potential prevention by black raspberry

El-Bayoumy, K., Chen, K. M., Zhang, S. M., Sun, Y. W., Amin, S., Stoner, G. & Guttenplan, J. B., Jan 1 2017, In : Chemical research in toxicology. 30, 1, p. 126-144 19 p.

Research output: Contribution to journalReview article

Mouth Neoplasms
Mouth
Environmental Carcinogens
Carcinogenesis
Animal Models
217 Citations (Scopus)

Catabolite activator protein: DNA binding and transcription activation

Lawson, C. L., Swigon, D., Murakami, K. S., Darst, S. A., Berman, H. M. & Ebright, R. H., Feb 2004, In : Current Opinion in Structural Biology. 14, 1, p. 10-20 11 p.

Research output: Contribution to journalReview article

Cyclic AMP Receptor Protein
Protein Binding
Transcriptional Activation
DNA
Protein C
37 Citations (Scopus)

Catalytic antibodies: Mechanistic and practical considerations

Stewart, J. D. & Benkovic, S., Dec 1 1993, In : Chemical Society Reviews. 22, 4, p. 213-219 7 p.

Research output: Contribution to journalReview article

Catalytic Antibodies

Catalytic antibodies.

Benkovic, S., 1991, In : Harvey lectures. 87, p. 115-128 14 p.

Research output: Contribution to journalReview article

Catalytic Antibodies
Anilides
Antibody Binding Sites
Molecular structure
Hydrolysis
19 Citations (Scopus)

Catalytic features, regulation and function of myocardial phospholipase A2

McHowat, J. & Creer, M., Jul 1 2004, In : Current Medicinal Chemistry: Cardiovascular and Hematological Agents. 2, 3, p. 209-218 10 p.

Research output: Contribution to journalReview article

Phospholipases A2
Phospholipids
Myocardium
Arachidonic Acid
Plasmalogens
38 Citations (Scopus)

CCR10 and its ligands in regulation of epithelial immunity and diseases

Xiong, N., Fu, Y., Hu, S., Xia, M. & Yang, J., Aug 2012, In : Protein and Cell. 3, 8, p. 571-580 10 p.

Research output: Contribution to journalReview article

Immunity
Epithelium
Tissue
Ligands
Skin
29 Citations (Scopus)

CD4 +CD25 +Foxp3 regulatoryTcells and vascular dysfunction in hypertension

Kassan, M., Wecker, A., Kadowitz, P., Trebak, M. & Matrougui, K., Oct 1 2013, In : Journal of hypertension. 31, 10, p. 1939-1943 5 p.

Research output: Contribution to journalReview article

Regulatory T-Lymphocytes
Blood Vessels
Cardiovascular Physiological Phenomena
Hypertension
Vasodilator Agents
57 Citations (Scopus)

Cell competition and its possible relation to cancer

Baker, N. E. & Li, W., Jul 15 2008, In : Cancer Research. 68, 14, p. 5505-5507 3 p.

Research output: Contribution to journalReview article

Neoplasms
Genotype
Warts
Cadaver
Drosophila
18 Citations (Scopus)

Cellular Organization of Neuroimmune Interactions in the Gastrointestinal Tract

Margolis, K. G., Gershon, M. D. & Bogunovic, M., Jul 1 2016, In : Trends in Immunology. 37, 7, p. 487-501 15 p.

Research output: Contribution to journalReview article

Neuroimmunomodulation
Enteric Nervous System
Conservation of Natural Resources
Nervous System
Vertebrates
25 Citations (Scopus)

Challenges for the development of ribonucleoside analogues as inducers of error catastrophe

Graci, J. D. & Cameron, C. E., Jan 2004, In : Antiviral Chemistry and Chemotherapy. 15, 1, p. 1-13 13 p.

Research output: Contribution to journalReview article

Ribonucleosides
RNA Viruses
Mutation Rate
Mutagenesis
Antiviral Agents
3 Citations (Scopus)

Changes in population characteristics and their implication on public health research

Du, P., Coles, F. B., O'Campo, P. & McNutt, L. A., Nov 19 2007, In : Epidemiologic Perspectives and Innovations. 4, 6.

Research output: Contribution to journalReview article

Censuses
Population Characteristics
Public Health
Research
Population
254 Citations (Scopus)

Chemical basis for enzyme catalysis

Bruice, T. C. & Benkovic, S. J., May 30 2000, In : Biochemistry. 39, 21, p. 6267-6274 8 p.

Research output: Contribution to journalReview article

Catalysis
Enzymes
41 Citations (Scopus)

Chemoprevention of breast cancer by fish oil in preclinical models: Trials and tribulations

Signori, C., El-Bayoumy, K., Russo, J., Thompson, H. J., Richie, J. P., Hartman, T. J. & Manni, A., Oct 1 2011, In : Cancer Research. 71, 19, p. 6091-6096 6 p.

Research output: Contribution to journalReview article

Fish Oils
Chemoprevention
Breast Neoplasms
Omega-3 Fatty Acids
Epidemiologic Studies