Research Output 1963 2020

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Review article
2015
241 Citations (Scopus)

Recent functional insights into the role of (p)ppGpp in bacterial physiology

Hauryliuk, V., Atkinson, G. C., Murakami, K., Tenson, T. & Gerdes, K., May 24 2015, In : Nature Reviews Microbiology. 13, 5, p. 298-309 12 p.

Research output: Contribution to journalReview article

Bacterial Physiological Phenomena
Guanosine Pentaphosphate
Guanosine Tetraphosphate
Guanosine Triphosphate
Bacteria
13 Citations (Scopus)

Regulation of intestinal IgA responses

Xiong, N. & Hu, S., Jul 24 2015, In : Cellular and Molecular Life Sciences. 72, 14, p. 2645-2655 11 p.

Research output: Contribution to journalReview article

Immunoglobulin A
Intestines
Antibody-Producing Cells
Maintenance
Bacteria
37 Citations (Scopus)

Selenium and inflammatory bowel disease

Kudva, A. K., Shay, A. E. & Prabhu, K. S., Jul 15 2015, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 309, 2, p. G71-G77

Research output: Contribution to journalReview article

Selenium
Inflammatory Bowel Diseases
Selenoproteins
Inflammation
Macrophages
101 Citations (Scopus)
Aryl Hydrocarbon Receptors
Microbiota
Tryptophan
Ligands
Pharmaceutical Preparations
41 Citations (Scopus)

Structural biology of bacterial RNA polymerase

Murakami, K. S., May 11 2015, In : Biomolecules. 5, 2, p. 848-864 17 p.

Research output: Contribution to journalReview article

Bacterial RNA
DNA-Directed RNA Polymerases
Transcription
X ray crystallography
X Ray Crystallography
27 Citations (Scopus)

Targeting ion channels for cancer therapy by repurposing the approved drugs

Kale, V. P., Amin, S. & Pandey, M. K., Oct 1 2015, In : Biochimica et Biophysica Acta - Biomembranes. 1848, 10, p. 2747-2755 9 p., 81871.

Research output: Contribution to journalReview article

Drug Repositioning
Ion Channels
Pharmaceutical Preparations
Neoplasms
Oncology
14 Citations (Scopus)

Targeting Peroxisome Proliferator-Activated Receptor-β/δ (PPARβ/δ) for Cancer Chemoprevention

Peters, J. M., Yao, P. L. & Gonzalez, F. J., Apr 1 2015, In : Current Pharmacology Reports. 1, 2, p. 121-128 8 p.

Research output: Contribution to journalReview article

Peroxisome Proliferator-Activated Receptors
Chemoprevention
Neoplasms
Cytoplasmic and Nuclear Receptors
Cell culture
2 Citations (Scopus)

The importance of mouse models to define immunovirologic determinants of progressive multifocal leukoencephalopathy

Frost, E. L. & Lukacher, A. E., Jan 1 2015, In : Frontiers in immunology. 6, JAN, 00646.

Research output: Contribution to journalReview article

Progressive Multifocal Leukoencephalopathy
Demyelinating Diseases
JC Virus
Central Nervous System
Polyomavirus
9 Citations (Scopus)

Unveiling the roles of HBV polymerase for new antiviral strategies

Clark, D. N. & Hu, J., Mar 1 2015, In : Future Virology. 10, 3, p. 283-295 13 p.

Research output: Contribution to journalReview article

Antiviral Agents
RNA-Directed DNA Polymerase
RNA-Binding Proteins
DNA
RNA Stability
9 Citations (Scopus)

Urothelial carcinoma with squamous differentiation-The pathologists' perspective

Gellert, L. L., Warrick, J. & Al-Ahmadie, H. A., Oct 1 2015, In : Urologic Oncology: Seminars and Original Investigations. 33, 10, p. 437-443 7 p.

Research output: Contribution to journalReview article

Squamous Cell Carcinoma
Histology
Carcinoma
Microscopy
Light
118 Citations (Scopus)

Vitamin D and 1,25(OH)2D regulation of T cells

Cantorna, M. T., Snyder, L., Lin, Y. D. & Yang, L., Apr 22 2015, In : Nutrients. 7, 4, p. 3011-3021 11 p.

Research output: Contribution to journalReview article

vitamin D
Vitamin D
T-lymphocytes
interleukin-4
Natural Killer T-Cells
2014
23 Citations (Scopus)

A risk for non-sexual transmission of human papillomavirus?

Ryndock, E. J. & Meyers, C., Oct 1 2014, In : Expert Review of Anti-Infective Therapy. 12, 10, p. 1165-1170 6 p.

Research output: Contribution to journalReview article

Papillomaviridae
Vertical Infectious Disease Transmission
Fomites
Papillomavirus Infections
Disinfectants
271 Citations (Scopus)

Aryl hydrocarbon receptor ligands in cancer: Friend and foe

Murray, I. A., Patterson, A. D. & Perdew, G. H., Nov 24 2014, In : Nature Reviews Cancer. 14, 12, p. 801-814 14 p.

Research output: Contribution to journalReview article

Aryl Hydrocarbon Receptors
Ligands
Neoplasms
Carcinogenesis
Dioxins
4 Citations (Scopus)

Diffuse large B-cell lymphoma of the prostate

Warrick, J. I., Owens, S. R. & Tomlins, S. A., Oct 1 2014, In : Archives of Pathology and Laboratory Medicine. 138, 10, p. 1286-1289 4 p.

Research output: Contribution to journalReview article

Lymphoma, Large B-Cell, Diffuse
Prostate
Lymphoma
B-Cell Chronic Lymphocytic Leukemia
Surgical Pathology
4 Citations (Scopus)

Functional implications of mitochondrial reactive oxygen species generated by oncogenic viruses

Choi, Y. B. & Harhaj, E. W., Dec 5 2014, In : Frontiers in Biology. 9, 6, p. 423-436 14 p.

Research output: Contribution to journalReview article

oncogenic viruses
Mitochondrial Degradation
Oncogenic Viruses
reactive oxygen species
Reactive Oxygen Species
37 Citations (Scopus)

Immune evasion strategies used by Helicobacter pylori

Lina, T. T., Alzahrani, S., Gonzalez, J., Pinchuk, I. V., Beswick, E. J. & Reyes, V. E., Sep 28 2014, In : World journal of gastroenterology. 20, 36, p. 12753-12766 14 p.

Research output: Contribution to journalReview article

Open Access
Immune Evasion
Helicobacter pylori
Infection
Stomach
Adaptive Immunity
65 Citations (Scopus)

Interplay between DNA repair and inflammation, and the link to cancer

Kidane, D., Chae, W. J., Czochor, J., Eckert, K. A., Glazer, P. M., Bothwell, A. L. M. & Sweasy, J. B., Jan 1 2014, In : Critical Reviews in Biochemistry and Molecular Biology. 49, 2, p. 116-139 24 p.

Research output: Contribution to journalReview article

DNA Repair
DNA Damage
Repair
Inflammation
DNA
21 Citations (Scopus)

Mammalian gut immunity

Chassaing, B., Kumar, M., Baker, M. T., Singh, V. & Vijay-Kumar, M., Sep 1 2014, In : Biomedical Journal. 37, 5, p. 246-258 13 p.

Research output: Contribution to journalReview article

Microbiota
Immune System
Immunity
Homeostasis
Hate
27 Citations (Scopus)

Microbial determinants of biochemical individuality and their impact on toxicology and pharmacology

Patterson, A. D. & Turnbaugh, P. J., Nov 4 2014, In : Cell Metabolism. 20, 5, p. 761-768 8 p.

Research output: Contribution to journalReview article

Precision Medicine
Individuality
Toxicology
Research Design
Pharmacology
43 Citations (Scopus)

Mode of action and dose-response framework analysis for receptor-mediated toxicity: The aryl hydrocarbon receptor as a case study

Budinsky, R. A., Schrenk, D., Simon, T., Van Den Berg, M., Reichard, J. F., Silkworth, J. B., Aylward, L. L., Brix, A., Gasiewicz, T., Kaminski, N., Perdew, G., Starr, T. B., Walker, N. J. & Rowlands, J. C., Jan 2014, In : Critical Reviews in Toxicology. 44, 1, p. 83-119 37 p.

Research output: Contribution to journalReview article

Aryl Hydrocarbon Receptors
Dioxins
Toxicity
Liver
Tumors
125 Citations (Scopus)

Mode of action and human relevance analysis for nuclear receptor-mediated liver toxicity: A case study with phenobarbital as a model constitutive androstane receptor (CAR) activator

Elcombe, C. R., Peffer, R. C., Wolf, D. C., Bailey, J., Bars, R., Bell, D., Cattley, R. C., Ferguson, S. S., Geter, D., Goetz, A., Goodman, J. I., Hester, S., Jacobs, A., Omiecinski, C. J., Schoeny, R., Xie, W. & Lake, B. G., Jan 2014, In : Critical Reviews in Toxicology. 44, 1, p. 64-82 19 p.

Research output: Contribution to journalReview article

Phenobarbital
Cytoplasmic and Nuclear Receptors
Liver
Toxicity
Tumors
103 Citations (Scopus)

Mode of action framework analysis for receptor-mediated toxicity: The peroxisome proliferator-activated receptor alpha (PPARα) as a case study

Corton, J. C., Cunningham, M. L., Hummer, B. T., Lau, C., Meek, B., Peters, J. M., Popp, J. A., Rhomberg, L., Seed, J. & Klaunig, J. E., Jan 2014, In : Critical Reviews in Toxicology. 44, 1, p. 1-49 49 p.

Research output: Contribution to journalReview article

PPAR alpha
Toxicity
Rodentia
Liver
Tumors
7 Citations (Scopus)

Quantitative gene analysis of methylation and expression (Q-GAME) in fresh or fixed cells and tissues

Wu, J., Salva, K. A., Stutz, N., Longley, B. J., Spiegelman, V. S. & Wood, G. S., May 2014, In : Experimental Dermatology. 23, 5, p. 304-309 6 p.

Research output: Contribution to journalReview article

Methylation
DNA Methylation
Genes
Tissue
Biopsy
15 Citations (Scopus)

Regulation of HTLV-1 tax stability, cellular trafficking and NF-κB activation by the ubiquitin-proteasome pathway

Lavorgna, A. & Harhaj, E. W., Oct 23 2014, In : Viruses. 6, 10, p. 3925-3943 19 p.

Research output: Contribution to journalReview article

Deltaretrovirus
Proteasome Endopeptidase Complex
Ubiquitin
T-Lymphocytes
Lysine
61 Citations (Scopus)

Sonic hedgehog signaling in basal cell nevus syndrome

Athar, M., Li, C., Kim, A. L., Spiegelman, V. S. & Bickers, D. R., Aug 29 2014, In : Cancer Research. 74, 18, p. 4967-4975 9 p.

Research output: Contribution to journalReview article

Basal Cell Nevus Syndrome
Cilia
HhAntag691
Clinical Trials
Neoplastic Processes
5 Citations (Scopus)

Splenic infarction caused by a rare coinfection of epstein-barr virus, cytomegalovirus, and mycoplasma pneumoniae

Li, Y., Pattan, V., Syed, B., Islam, M. & Yousif, A., Jan 1 2014, In : Pediatric Emergency Care. 30, 9, p. 636-637 2 p.

Research output: Contribution to journalReview article

Splenic Infarction
Mycoplasma pneumoniae
Cytomegalovirus
Human Herpesvirus 4
Coinfection
3 Citations (Scopus)

Targeting estrogen receptor-β for the prevention of nonmelanoma skin cancer

Yao, P. L., Gonzalez, F. J. & Peters, J. M., Feb 1 2014, In : Cancer Prevention Research. 7, 2, p. 182-185 4 p.

Research output: Contribution to journalReview article

Skin Neoplasms
Estrogen Receptors
Epithelial-Mesenchymal Transition
Estrogens
Catenins
6 Citations (Scopus)

Targeting structural dynamics of the RNA-dependent RNA polymerase for anti-viral strategies

Boehr, D. D., Liu, X. & Yang, X., Jan 1 2014, In : Current Opinion in Virology. 9, p. 194-200 7 p.

Research output: Contribution to journalReview article

RNA Replicase
Viruses
Attenuated Vaccines
Drug Design
RNA Viruses
31 Citations (Scopus)

The microbiome and obesity-An established risk for certain types of cancer

Rogers, C. J., Prabhu, K. S. & Vijay-Kumar, M., 2014, In : Cancer journal (Sudbury, Mass.). 20, 3, p. 176-180 5 p.

Research output: Contribution to journalReview article

Microbiota
Obesity
Neoplasms
Carcinogenesis
Dysbiosis
57 Citations (Scopus)

The unique chemistry of benzoxaboroles: Current and emerging applications in biotechnology and therapeutic treatments

Liu, C. T., Tomsho, J. W. & Benkovic, S., Aug 15 2014, In : Bioorganic and Medicinal Chemistry. 22, 16, p. 4462-4473 12 p.

Research output: Contribution to journalReview article

Biotechnology
Acyclic Acids
Boronic Acids
Chemical reactivity
Materials science
29 Citations (Scopus)

Utilizing regulatory T cells against rheumatoid arthritis

Haque, M., Fino, K., Lei, F., Xiong, X. & Song, J., Jan 1 2014, In : Frontiers in Oncology. 4 JUL, 209.

Research output: Contribution to journalReview article

Regulatory T-Lymphocytes
Rheumatoid Arthritis
Self Tolerance
Homeostasis
Immune Tolerance
2013
18 Citations (Scopus)

BRCA1 and BRCA2 mutations in the ovarian cancer population across race and ethnicity: Special reference to Asia

Shanmughapriya, S., Nachiappan, V. & Natarajaseenivasan, K., Jan 1 2013, In : Oncology (Switzerland). 84, 4, p. 226-232 7 p.

Research output: Contribution to journalReview article

Ovarian Neoplasms
Mutation
Population
Iceland
Aptitude
29 Citations (Scopus)

CD4 +CD25 +Foxp3 regulatoryTcells and vascular dysfunction in hypertension

Kassan, M., Wecker, A., Kadowitz, P., Trebak, M. & Matrougui, K., Oct 1 2013, In : Journal of hypertension. 31, 10, p. 1939-1943 5 p.

Research output: Contribution to journalReview article

Regulatory T-Lymphocytes
Blood Vessels
Cardiovascular Physiological Phenomena
Hypertension
Vasodilator Agents

Future virology: A mitochondriac's perspective

Cameron, C. E., Oct 1 2013, In : Future Virology. 8, 10, p. 933-935 3 p.

Research output: Contribution to journalReview article

Virology
Immunity
Mitochondria
26 Citations (Scopus)

Immunometabolic role of long-chain omega-3 fatty acids in obesity-induced inflammation

Flock, M. R., Rogers, C. J., Prabhu, K. S. & Kris-Etherton, P. M., Sep 1 2013, In : Diabetes/Metabolism Research and Reviews. 29, 6, p. 431-445 15 p.

Research output: Contribution to journalReview article

Eicosapentaenoic Acid
Docosahexaenoic Acids
Omega-3 Fatty Acids
Obesity
Inflammation
35 Citations (Scopus)

Intersection of Hippo/YAP and Wnt/β-catenin signaling pathways

Konsavage, W. M. & Yochum, G. S., Jan 1 2013, In : Acta Biochimica et Biophysica Sinica. 45, 2, p. 71-79 9 p.

Research output: Contribution to journalReview article

Catenins
Wnt Signaling Pathway
Carcinogenesis
Homeostasis
Repair
62 Citations (Scopus)

Is selenium a potential treatment for cancer metastasis?

Chen, Y. C., Sandeep Prabhu, K. & Mastro, A. M., Apr 8 2013, In : Nutrients. 5, 4, p. 1149-1168 20 p.

Research output: Contribution to journalReview article

Selenium
metastasis
Selenoproteins
selenium
Neoplasm Metastasis
34 Citations (Scopus)

Lab-on-a-chip technologies for single-molecule studies

Zhao, Y., Chen, D., Yue, H., French, J. B., Rufo, J., Benkovic, S. J. & Huang, T. J., Jun 21 2013, In : Lab on a Chip. 13, 12, p. 2183-2198 16 p.

Research output: Contribution to journalReview article

Lab-on-a-chip
Nanopores
Technology
Equipment and Supplies
Molecules
12 Citations (Scopus)

Metabolomics: An essential tool to understand the function of peroxisome proliferator-activated receptor alpha

Montanez, J. E., Peters, J. M., Correll, J. B., Gonzalez, F. J. & Patterson, A. D., Feb 1 2013, In : Toxicologic Pathology. 41, 2, p. 410-418 9 p.

Research output: Contribution to journalReview article

PPAR alpha
Peroxisome Proliferator-Activated Receptors
Metabolomics
Toxicity
Chemical and Drug Induced Liver Injury
15 Citations (Scopus)

Nuclear trafficking of retroviral RNAs and gag proteins during late steps of replication

Stake, M. S., Bann, D. V., Kaddis, R. J. & Parent, L. J., Nov 18 2013, In : Viruses. 5, 11, p. 2767-2795 29 p.

Research output: Contribution to journalReview article

gag Gene Products
Viral RNA
Cell Nucleus Active Transport
RNA
Retroviridae
11 Citations (Scopus)

Par-4 as a potential target for cancer therapy

Irby, R. & Kline, C. L., Jan 1 2013, In : Expert Opinion on Therapeutic Targets. 17, 1, p. 77-87 11 p.

Research output: Contribution to journalReview article

Apoptosis
Tumor Suppressor Proteins
Neoplasms
Cell death
Tumors
112 Citations (Scopus)

Peptidylarginine deiminases in citrullination, gene regulation, health and pathogenesis

Wang, S. & Wang, Y., Oct 1 2013, In : Biochimica et Biophysica Acta - Gene Regulatory Mechanisms. 1829, 10, p. 1126-1135 10 p.

Research output: Contribution to journalReview article

Gene expression
Arginine
Health
Enzymes
Genes
17 Citations (Scopus)

Post SELECT: Selenium on trial

Sharma, A. & Amin, S., Feb 1 2013, In : Future Medicinal Chemistry. 5, 2, p. 163-174 12 p.

Research output: Contribution to journalReview article

Selenium Compounds
Selenium
Selenomethionine
Trace Elements
Pharmaceutical Preparations
43 Citations (Scopus)

Probing cell-cell communication with microfluidic devices

Guo, F., French, J. B., Li, P., Zhao, H., Chan, C. Y., Fick, J. R., Benkovic, S. J. & Huang, T. J., Aug 21 2013, In : Lab on a Chip. 13, 16, p. 3152-3162 11 p.

Research output: Contribution to journalReview article

Lab-On-A-Chip Devices
Microfluidics
Cell Communication
Communication
Physiological Phenomena
18 Citations (Scopus)

Tumor-specific microsatellite instability: Do distinct mechanisms underlie the MSI-L and EMAST phenotypes?

Hile, S. E., Shabashev, S. & Eckert, K., Mar 1 2013, In : Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 743-744, p. 67-77 11 p.

Research output: Contribution to journalReview article

Microsatellite Instability
Phenotype
Neoplasms
Microsatellite Repeats
N-methylsuccinimide
22 Citations (Scopus)

What Role for Store-Operated Ca2+ Entry in Muscle?

Trebak, M., Zhang, W., Ruhle, B., Henkel, M. M., González-Cobos, J. C., Motiani, R. K., Stolwijk, J. A., Newton, R. L. & Zhang, X., May 1 2013, In : Microcirculation. 20, 4, p. 330-336 7 p.

Research output: Contribution to journalReview article

Endoplasmic Reticulum
Muscles
Skeletal Muscle
Enzyme Activation
Inositol 1,4,5-Trisphosphate
2012
17 Citations (Scopus)

Application of live-cell RNA imaging techniques to the study of retroviral RNA trafficking

Bann, D. V. & Parent, L. J., Jun 15 2012, In : Viruses. 4, 6, p. 963-979 17 p.

Research output: Contribution to journalReview article

RNA
Retroviridae
Virion
Viral Structural Proteins
Cell Nucleus Active Transport
38 Citations (Scopus)

CCR10 and its ligands in regulation of epithelial immunity and diseases

Xiong, N., Fu, Y., Hu, S., Xia, M. & Yang, J., Aug 2012, In : Protein and Cell. 3, 8, p. 571-580 10 p.

Research output: Contribution to journalReview article

Immunity
Epithelium
Tissue
Ligands
Skin
21 Citations (Scopus)

Consortium biology in immunology: The perspective from the Immunological Genome Project

Benoist, C., Lanier, L., Merad, M., Mathis, D., Ericson, J., Painter, M., Davis, S., Laplace, C., Hyatt, G., Paik, H., Rothamel, K., Cruse, R., Doran, G., Heng, T., Asinovski, N., Ortiz-Lopes, A., Ergun, A., Gray, D., Wakamatsu, E., Hill, J. & 70 others, Mingueneau, M., Cipolletta, D., Yoshida, H., Cohen, N., Kim, E., Brennan, P., Lynch, L., Brenner, M., Costello, J., Collins, J. J., Blair, D., Dustin, M., Knell, J., Yang, E., Best, A., Shaw, L., Doedens, A., Goldrath, A., Shinton, S., Zhou, Y., Hardy, R., Jojic, V., Mostafavi, S., Koller, D., Jianu, R., Laidlaw, D., Bezman, N., Sun, J., Zhu, Y., Hendricks, D., Kamimura, Y., Min-Oo, G., Hendricks, D., Morvan, M., Kamimura, Y., Nabekura, T., Lam, V., Kim, C., Greter, M., Helft, J., Chow, A., Bogunovic, M., Mortha, A., Price, J., Hashimoto, D., Miller, J., Sathe, P., Chudnovskiy, A., Lavin, Y., Idoyaga, J., Gautier, E., Jakubzick, C., D'Angelo, J., Randolph, G., Shay, T., Regev, A., Gazit, R., Rossi, D., Kreslawsky, T., von Bohmer, H., Bellemare-Pelletier, A., Elpek, K., Spelv, L., Fletcher, A., Malhotra, D., Cremasco, V., Turley, S., Kim, F., Nageswara Rao, T. & Wagers, A., Oct 1 2012, In : Nature Reviews Immunology. 12, 10, p. 734-740 7 p.

Research output: Contribution to journalReview article

Allergy and Immunology
Genome
Research Personnel
Research
26 Citations (Scopus)

Human mitochondrial RNA polymerase: Structure-function, mechanism and inhibition

Arnold, J. J., Smidansky, E. D., Moustafa, I. & Cameron, C. E., Sep 1 2012, In : Biochimica et Biophysica Acta - Gene Regulatory Mechanisms. 1819, 9-10, p. 948-960 13 p.

Research output: Contribution to journalReview article

Mitochondrial Genome
Human Genome
DNA-Directed RNA Polymerases
Transcription
DNA Primase