Research Output 1963 2020

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Review article
2012
15 Citations (Scopus)

Inflammation, Immunity, and Vaccines for Helicobacter pylori Infection

Ihan, A., Pinchuk, I. V. & Beswick, E. J., Sep 1 2012, In : Helicobacter. 17, SUPPL.1, p. 16-21 6 p.

Research output: Contribution to journalReview article

Open Access
Helicobacter Infections
Helicobacter pylori
Immunity
Vaccines
Inflammation
71 Citations (Scopus)

Merlin: A tumour suppressor with functions at the cell cortex and in the nucleus

Li, W., Cooper, J., Karajannis, M. A. & Giancotti, F. G., Mar 2012, In : EMBO Reports. 13, 3, p. 204-215 12 p.

Research output: Contribution to journalReview article

Neurofibromin 2
Tumors
Neoplasms
Contact Inhibition
Catenins
23 Citations (Scopus)

Mononuclear phagocyte diversity in the intestine

Bogunovic, M., Mortha, A., Muller, P. A. & Merad, M., Dec 1 2012, In : Immunologic Research. 54, 1-3, p. 37-49 13 p.

Research output: Contribution to journalReview article

Phagocytes
Intestines
Antigens
Intestinal Mucosa
Autoantigens
5 Citations (Scopus)

Recruitment of transcription complexes to enhancers and the role of enhancer transcription

Stees, J. S., Varn, F., Huang, S., Strouboulis, J. & Bungert, J., Dec 5 2012, In : Biology. 1, 3, p. 778-793 16 p.

Research output: Contribution to journalReview article

RNA Polymerase II
Gene Expression Regulation
Transcription
transcription (genetics)
Gene Expression
160 Citations (Scopus)

Regulation of NF-κB by deubiquitinases

Harhaj, E. W. & Dixit, V. M., Mar 1 2012, In : Immunological Reviews. 246, 1, p. 107-124 18 p.

Research output: Contribution to journalReview article

Ubiquitin
Polyubiquitin
Ubiquitin-Protein Ligases
Ubiquitination
Adaptive Immunity
95 Citations (Scopus)

Regulation of NF-κB signaling by the A20 deubiquitinase

Shembade, N. & Harhaj, E. W., Mar 1 2012, In : Cellular and Molecular Immunology. 9, 2, p. 123-130 8 p.

Research output: Contribution to journalReview article

Autoimmune Diseases
Phosphotransferases
Polyubiquitin
Inflammation
Ubiquitination
51 Citations (Scopus)

STIM/Orai signalling complexes in vascular smooth muscle

Trebak, M., Sep 1 2012, In : Journal of Physiology. 590, 17, p. 4201-4208 8 p.

Research output: Contribution to journalReview article

Vascular Smooth Muscle
Endoplasmic Reticulum
Cell Membrane
Proteins
EF Hand Motifs
225 Citations (Scopus)

The role of peroxisome proliferator-activated receptors in carcinogenesis and chemoprevention

Peters, J. M., Shah, Y. M. & Gonzalez, F. J., Mar 1 2012, In : Nature Reviews Cancer. 12, 3, p. 181-195 15 p.

Research output: Contribution to journalReview article

Peroxisome Proliferator-Activated Receptors
Chemoprevention
Carcinogenesis
Neoplasms
Metabolic Diseases
31 Citations (Scopus)

Understanding resistance to combination chemotherapy

Pritchard, J. R., Lauffenburger, D. A. & Hemann, M. T., Oct 1 2012, In : Drug Resistance Updates. 15, 5-6, p. 249-257 9 p.

Research output: Contribution to journalReview article

Combination Drug Therapy
Pharmaceutical Preparations
Neoplasms
Therapeutics
Investigational Therapies
66 Citations (Scopus)

Vitamin D, multiple sclerosis and inflammatory bowel disease

Cantorna, M. T-A., Jul 1 2012, In : Archives of Biochemistry and Biophysics. 523, 1, p. 103-106 4 p.

Research output: Contribution to journalReview article

Inflammatory Bowel Diseases
Vitamin D
Multiple Sclerosis
Calcitriol Receptors
T-cells
20 Citations (Scopus)

Where EGF receptors transmit their signals

Lill, N. & Sever, N. I., Sep 25 2012, In : Science signaling. 5, 243, pe41.

Research output: Contribution to journalReview article

Endosomal Sorting Complexes Required for Transport
Epidermal Growth Factor Receptor
Endosomes
Receptor Protein-Tyrosine Kinases
Neoplasms
2011
16 Citations (Scopus)

Beyond plasma membrane targeting: Role of the MA domain of Gag in retroviral genome encapsidation

Parent, L. J. & Gudleski, N., Jul 22 2011, In : Journal of Molecular Biology. 410, 4, p. 553-564 12 p.

Research output: Contribution to journalReview article

gag Gene Products
Product Packaging
Cell Membrane
Genome
Virus Assembly
141 Citations (Scopus)

Boron-containing inhibitors of synthetases

Baker, S. J., Tomsho, J. W. & Benkovic, S., Aug 1 2011, In : Chemical Society Reviews. 40, 8, p. 4279-4285 7 p.

Research output: Contribution to journalReview article

Boronic Acids
Boron
Ligases
Pharmaceutical Preparations
Nucleophiles
41 Citations (Scopus)

Chemoprevention of breast cancer by fish oil in preclinical models: Trials and tribulations

Signori, C., El-Bayoumy, K., Russo, J., Thompson, H. J., Richie, J. P., Hartman, T. J. & Manni, A., Oct 1 2011, In : Cancer Research. 71, 19, p. 6091-6096 6 p.

Research output: Contribution to journalReview article

Fish Oils
Chemoprevention
Breast Neoplasms
Omega-3 Fatty Acids
Epidemiologic Studies
151 Citations (Scopus)

Deubiquitinases in the regulation of NF-κB signaling

Harhaj, E. W. & Dixit, V. M., Jan 1 2011, In : Cell Research. 21, 1, p. 22-39 18 p.

Research output: Contribution to journalReview article

NF-kappa B
Ubiquitin-Protein Ligases
Down-Regulation
Ubiquitination
Adaptive Immunity
36 Citations (Scopus)

Dissecting the role of peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) in colon, breast, and lung carcinogenesis

Peters, J. M., Foreman, J. E. & Gonzalez, F. J., Dec 1 2011, In : Cancer and Metastasis Reviews. 30, 3-4, p. 619-640 22 p.

Research output: Contribution to journalReview article

Peroxisome Proliferator-Activated Receptors
Colon
Carcinogenesis
Breast
Lung
18 Citations (Scopus)

Diverse roles of non-diverse molecules: MHC class Ib molecules in host defense and control of autoimmunity

Hofstetter, A. R., Sullivan, L. C., Lukacher, A. & Brooks, A. G., Feb 1 2011, In : Current Opinion in Immunology. 23, 1, p. 104-110 7 p.

Research output: Contribution to journalReview article

Autoimmunity
T-Lymphocytes
Histocompatibility Antigens Class I
T-Lymphocyte Subsets
Adaptive Immunity
7 Citations (Scopus)

Heparin-induced thrombocytopenia and cerebral venous sinus thrombosis: Case report and literature review

Fesler, M. J., Creer, M., Richart, J. M., Edgell, R., Havlioglu, N., Norfleet, G. & Cruz-Flores, S., Aug 1 2011, In : Neurocritical Care. 15, 1, p. 161-165 5 p.

Research output: Contribution to journalReview article

Intracranial Sinus Thrombosis
Venous Thrombosis
Thrombocytopenia
Heparin
Seizures
109 Citations (Scopus)

High-resolution genome-wide mapping of the primary structure of chromatin

Zhang, Z. & Pugh, B. F., Jan 21 2011, In : Cell. 144, 2, p. 175-186 12 p.

Research output: Contribution to journalReview article

Chromosome Mapping
Chromatin
Genes
Nucleosomes
High-Throughput Nucleotide Sequencing
28 Citations (Scopus)

Immune activation resulting from NKG2D/ligand interaction promotes atherosclerosis

Xia, M., Guerra, N., Sukhova, G. K., Yang, K., Miller, C. K., Shi, G. P., Raulet, D. H. & Xiong, N., Dec 20 2011, In : Circulation. 124, 25, p. 2933-2943 11 p.

Research output: Contribution to journalReview article

Atherosclerosis
Ligands
Inflammation
Hyperglycemia
Metabolic Diseases
79 Citations (Scopus)

Intestinal myofibroblasts: Targets for stem cell therapy

Mifflin, R. C., Pinchuk, I. V., Saada, J. I. & Powell, D. W., May 1 2011, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 300, 5, p. G684-G696

Research output: Contribution to journalReview article

Myofibroblasts
Cell- and Tissue-Based Therapy
Pericytes
Stem Cells
Mucous Membrane
13 Citations (Scopus)
Peroxisome Proliferator-Activated Receptors
Carcinogenesis
Inflammation
Peroxisomes
Metabolic Diseases
60 Citations (Scopus)

Neuroendocrine-immune interactions and responses to exercise

Fragala, M. S., Kraemer, W. J., Denegar, C. R., Maresh, C. M., Mastro, A. M. & Volek, J. S., Jul 29 2011, In : Sports Medicine. 41, 8, p. 621-639 19 p.

Research output: Contribution to journalReview article

Immune System
Neurosecretory Systems
Physiological Stress
Adaptive Immunity
Exercise
16 Citations (Scopus)

Promoting wellness in Alaskan villages: Integrating traditional knowledge and science of wild berries

Flint, C. G., Robinson, E. S., Kellogg, J., Ferguson, G., BouFajreldin, L., Dolan, M., Raskin, I. & Lila, M. A., Jun 1 2011, In : EcoHealth. 8, 2, p. 199-209 11 p.

Research output: Contribution to journalReview article

traditional knowledge
Fruit
village
cultural tradition
food
29 Citations (Scopus)

Role of helix-loop-helix proteins during differentiation of erythroid cells

Anantharaman, A., Lin, I. J., Barrow, J., Liang, S. Y., Masannat, J., Strouboulis, J., Huang, S. & Bungert, J., Apr 1 2011, In : Molecular and cellular biology. 31, 7, p. 1332-1343 12 p.

Research output: Contribution to journalReview article

Erythroid Cells
Proteins
Erythroid Precursor Cells
Hematopoiesis
Transcription Factors
16 Citations (Scopus)

STIM1 and Orai1: Novel targets for vascular diseases?

Zhang, W. & Trebak, M., Aug 1 2011, In : Science China Life Sciences. 54, 8, p. 780-785 6 p.

Research output: Contribution to journalReview article

vascular diseases
Lymphocyte Activation
Vascular Diseases
Endoplasmic Reticulum
Blood Vessels
40 Citations (Scopus)

Targeting the NS5A protein of HCV: An emerging option

Cordek, D. G., Bechtel, J. T., Maynard, A. T., Kazmierski, W. M. & Cameron, C. E., Sep 2011, In : Drugs of the Future. 36, 9, p. 691-711 21 p.

Research output: Contribution to journalReview article

Protein C
Hepacivirus
Genotype
Ribavirin
Phosphoproteins
616 Citations (Scopus)

The ESCRT Pathway

Henne, W. M., Buchkovich, N. & Emr, S. D., Jul 19 2011, In : Developmental Cell. 21, 1, p. 77-91 15 p.

Research output: Contribution to journalReview article

Endosomal Sorting Complexes Required for Transport
Multivesicular Bodies
Membranes
Vacuoles
Lysosomes
22 Citations (Scopus)

Why toxic equivalency factors are not suitable for perfluoroalkyl chemicals

Peters, J. M. & Gonzalez, F. J., Oct 17 2011, In : Chemical research in toxicology. 24, 10, p. 1601-1609 9 p.

Research output: Contribution to journalReview article

Peroxisome Proliferator-Activated Receptors
Poisons
Polychlorinated Biphenyls
Animal Models
Toxicity
160 Citations (Scopus)
Biochemical Phenomena
Xenobiotics
Metabolism
Toxicity
Toxicology
2010
7 Citations (Scopus)

Analysis of the DNA translocation and unwinding activities of T4 phage helicases

Perumal, S. K., Raney, K. D. & Benkovic, S., Jul 1 2010, In : Methods. 51, 3, p. 277-288 12 p.

Research output: Contribution to journalReview article

Bacteriophage T4
Bacteriophages
DNA
RNA
Biological Phenomena
128 Citations (Scopus)

Breast cancer metastasis to the bone: Mechanisms of bone loss

Chen, Y. C., Sosnoski, D. M. & Mastro, A. M., Dec 16 2010, In : Breast Cancer Research. 12, 6, 215.

Research output: Contribution to journalReview article

Osteoclasts
Osteoblasts
Breast Neoplasms
Neoplasm Metastasis
Bone and Bones
118 Citations (Scopus)

Coupled motions in enzyme catalysis

Nashine, V. C., Hammes-Schiffer, S. & Benkovic, S., Oct 1 2010, In : Current Opinion in Chemical Biology. 14, 5, p. 644-651 8 p.

Research output: Contribution to journalReview article

Catalysis
Enzymes
Electron transitions
Ground state
Proteins
2 Citations (Scopus)

Cross-protective responses to human papillomavirus infection

Christensen, N. & Bounds, C. E., Mar 1 2010, In : Future Virology. 5, 2, p. 163-174 12 p.

Research output: Contribution to journalReview article

Virus-Like Particle Vaccines
Papillomavirus Infections
Cross Protection
Papillomavirus Vaccines
Papillomaviridae
79 Citations (Scopus)

Defective mismatch repair, microsatellite mutation bias, and variability in clinical cancer phenotypes

Shah, S. N., Hile, S. E. & Eckert, K. A., Jan 15 2010, In : Cancer Research. 70, 2, p. 431-435 5 p.

Research output: Contribution to journalReview article

DNA Mismatch Repair
Microsatellite Repeats
Phenotype
Microsatellite Instability
Mutation
23 Citations (Scopus)

Expanding knowledge of P3 proteins in the poliovirus lifecycle

Cameron, C. E., Suk Oh, H. & Moustafa, I., Jun 1 2010, In : Future microbiology. 5, 6, p. 867-881 15 p.

Research output: Contribution to journalReview article

Poliovirus
Genome
Proteins
Viral RNA
Picornaviridae
73 Citations (Scopus)

Interplay between calcium and reactive Oxygen/Nitrogen species: An essential paradigm for vascular smooth muscle signaling

Trebak, M., Ginnan, R., Singer, H. A. & Jourd'Heuil, D., Mar 1 2010, In : Antioxidants and Redox Signaling. 12, 5, p. 657-674 18 p.

Research output: Contribution to journalReview article

Reactive Nitrogen Species
Vascular Smooth Muscle
Muscle
Reactive Oxygen Species
Nitrogen
46 Citations (Scopus)

Intestinal mesenchymal cells

Pinchuk, I., Mifflin, R. C., Saada, J. I. & Powell, D. W., Oct 1 2010, In : Current gastroenterology reports. 12, 5, p. 310-318 9 p.

Research output: Contribution to journalReview article

Myofibroblasts
Mucous Membrane
Stem Cell Niche
Intestinal Neoplasms
Intestinal Diseases
15 Citations (Scopus)

Merlin's tumor suppression linked to inhibition of the E3 ubiquitin ligase CRL4DCAF1

Li, W. & Giancotti, F. G., Nov 15 2010, In : Cell Cycle. 9, 22, p. 4433-4436 4 p.

Research output: Contribution to journalReview article

Neurofibromin 2
Ubiquitin-Protein Ligases
Neoplasms
Neurofibromatosis 2
Cell Proliferation
153 Citations (Scopus)

Origin and functional heterogeneity of non-lymphoid tissue dendritic cells in mice

Helft, J., Ginhoux, F., Bogunovic, M. & Merad, M., Mar 1 2010, In : Immunological Reviews. 234, 1, p. 55-75 21 p.

Research output: Contribution to journalReview article

Dendritic Cells
Cell Lineage
Immunity
Homeostasis
Vaccines
11 Citations (Scopus)

Single-molecule studies of DNA replisome function

Perumal, S. K., Yue, H., Hu, Z., Spiering, M. M. & Benkovic, S., May 1 2010, In : Biochimica et Biophysica Acta - Proteins and Proteomics. 1804, 5, p. 1094-1112 19 p.

Research output: Contribution to journalReview article

DNA Replication
Molecules
DNA
Biophysics
Biochemistry
3 Citations (Scopus)

Some unmet challenges in the immunology of viral infections.

Rouse, B. T. & Lukacher, A., Jan 1 2010, In : Discovery medicine. 10, 53, p. 363-370 8 p.

Research output: Contribution to journalReview article

Virus Diseases
Allergy and Immunology
Viral Vaccines
Viruses
Adaptive Immunity
204 Citations (Scopus)

Staphylococcal Enterotoxins

Pinchuk, I. V., Beswick, E. J. & Reyes, V. E., Aug 1 2010, In : Toxins. 2, 8, p. 2177-2197 21 p.

Research output: Contribution to journalReview article

Open Access
Enterotoxins
Staphylococcus aureus
T-cells
Poisons
Septic Shock
133 Citations (Scopus)

Theoretical perspectives on protein folding

Thirumalai, D., O'Brien, E. P., Morrison, G. & Hyeon, C., Jun 9 2010, In : Annual Review of Biophysics. 39, 1, p. 159-183 25 p.

Research output: Contribution to journalReview article

Protein folding
Protein Folding
Proteins
Molecular Models
Freezing
15 Citations (Scopus)

The puzzling role of TRPC3 channels in motor coordination

Trebak, M., Feb 1 2010, In : Pflugers Archiv European Journal of Physiology. 459, 3, p. 369-375 7 p.

Research output: Contribution to journalReview article

Knockout Mice
Cations
Phenotype
Growth Cones
Purkinje Cells
55 Citations (Scopus)

TRPC channels in smooth muscle cells

Gonzalez-Cobos, J. C. & Trebak, M., Jun 1 2010, In : Frontiers in Bioscience. 15, 3, p. 1023-1039 17 p.

Research output: Contribution to journalReview article

Transient Receptor Potential Channels
Smooth Muscle Myocytes
Smooth Muscle
Muscle
Cells
36 Citations (Scopus)

Xenobiotic metabolism: A view through the metabolometer

Patterson, A. D., Gonzalez, F. J. & Idle, J. R., May 17 2010, In : Chemical research in toxicology. 23, 5, p. 851-860 10 p.

Research output: Contribution to journalReview article

Xenobiotics
Metabolism
aminoflavone
Arecoline
Areca
2009
28 Citations (Scopus)

Archaeal RNA polymerase

Hirata, A. & Murakami, K. S., Dec 1 2009, In : Current Opinion in Structural Biology. 19, 6, p. 724-731 8 p.

Research output: Contribution to journalReview article

Archaeal RNA
DNA-Directed RNA Polymerases
Eukaryota
General Transcription Factors
Archaea
59 Citations (Scopus)

A three-dimensional osteogenic tissue model for the study of metastatic tumor cell interactions with bone

Mastro, A. M. & Vogler, E. A., May 15 2009, In : Cancer Research. 69, 10, p. 4097-4100 4 p.

Research output: Contribution to journalReview article

Osteoblasts
Cell Communication
Bone and Bones
Bioreactors
Osteocytes
38 Citations (Scopus)

Dynamics: the missing link between structure and function of the viral RNA-dependent RNA polymerase?

Cameron, C. E., Moustafa, I. & Arnold, J. J., Dec 1 2009, In : Current Opinion in Structural Biology. 19, 6, p. 768-774 7 p.

Research output: Contribution to journalReview article

RNA Replicase
Viral RNA
Nucleotides
Nucleosides
Nucleic Acids