Center for Statistical Genetics

  • United States

Organization profile

Organization profile

Research Interests

Fingerprint The fingerprint is based on mining the text of the scientific documents related to the associated persons. Based on that an index of weighted terms is created, which defines the key subjects of research unit

Quantitative Trait Loci Medicine & Life Sciences
Genes Medicine & Life Sciences
Asthma Medicine & Life Sciences
Statistical Models Medicine & Life Sciences
Genome Medicine & Life Sciences
Populus Medicine & Life Sciences
quantitative trait loci Agriculture & Biology
Growth Medicine & Life Sciences

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Profiles

No photo of Naomi S. Altman
19902019
No photo of Lin Lin

Lin Lin

Person: Academic

20102019

Research Output 1982 2019

A Bayesian joint model of recurrent events and a terminal event

Li, Z., Chinchilli, V. & Wang, M., Jan 1 2019, In : Biometrical Journal. 61, 1, p. 187-202 16 p.

Research output: Contribution to journalArticle

Recurrent Events
Joint Model
Bayesian Model
Frailty
Frailty Model
1 Citation (Scopus)

A computational framework to assess genome-wide distribution of polymorphic human endogenous retrovirus-k in human populations

Li, W., Lin, L., Malhotra, R., Yang, L., Acharya, R. & Poss, M., Mar 1 2019, In : PLoS computational biology. 15, 3, e1006564.

Research output: Contribution to journalArticle

Open Access
Retroviridae
Endogenous Retroviruses
human population
Genome
genome
1 Citation (Scopus)

Adapting clinical trial design to maintain meaningful outcomes during a multicenter asthma trial in the precision medicine era

On behalf of the National Heart Lung and Blood Institute's “AsthmaNet”, Feb 1 2019, In : Contemporary Clinical Trials. 77, p. 98-103 6 p.

Research output: Contribution to journalArticle

Precision Medicine
Multicenter Studies
Asthma
Eosinophils
Clinical Trials

A dissection model for mapping complex traits

Sang, M., Shi, H., Wei, K., Ye, M., Jiang, L., Sun, L. & Wu, R., Mar 1 2019, In : Plant Journal. 97, 6, p. 1168-1182 15 p.

Research output: Contribution to journalArticle

Dissection
quantitative trait loci
DNA Shuffling
Genetic Selection
Quantitative Trait Loci
1 Citation (Scopus)

Analyzing outliers: robust methods to the rescue

Greco, L., Luta, G., Krzywinski, M. & Altman, N. S., Apr 1 2019, In : Nature methods. 16, 4, p. 275-276 2 p.

Research output: Contribution to journalComment/debate

1 Citation (Scopus)
DNA Methylation
Body Mass Index
Obesity
Genes
Pediatric Obesity
7 Citations (Scopus)

Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use

23andMe Research Team, HUNT All-In Psychiatry, Liu, M., Jiang, Y., Wedow, R., Li, Y., Brazel, D. M., Chen, F., Datta, G., Davila-Velderrain, J., McGuire, D., Tian, C., Zhan, X., Agee, M., Alipanahi, B., Auton, A., Bell, R. K., Bryc, K., Elson, S. L., Fontanillas, P. & 32 othersFurlotte, N. A., Hinds, D. A., Hromatka, B. S., Huber, K. E., Kleinman, A., Litterman, N. K., McIntyre, M. H., Mountain, J. L., Northover, C. A. M., Sathirapongsasuti, J. F., Sazonova, O. V., Shelton, J. F., Shringarpure, S., Tian, C., Tung, J. Y., Vacic, V., Wilson, C. H., Pitts, S. J., Mitchell, A., Skogholt, A. H., Winsvold, B. S., Sivertsen, B., Stordal, E., Morken, G., Kallestad, H., Heuch, I., Zwart, J. A., Fjukstad, K. K., Pedersen, L. M., Gabrielsen, M. E., Johnsen, M. B. & Liu, D., Feb 1 2019, In : Nature Genetics. 51, 2, p. 237-244 8 p.

Research output: Contribution to journalLetter

Tobacco Use
Alcohols
Tobacco Use Cessation
Genetic Association Studies
Synaptic Transmission
Hormone Replacement Therapy
Coronary Disease
Meta-Analysis
Stroke
Regression Analysis

A unified DNA sequence and non-DNA sequence mapping model of complex traits

Zeng, Y., Zhu, X., Chen, C., Banerjee, K., Sun, L., Yu, W., Zheng, B. & Wu, R., Jan 1 2019, In : Plant Journal.

Research output: Contribution to journalArticle

Chromosome Mapping
Quantitative Trait Loci
DNA sequences
chromosome mapping
Seed

A unified mapping framework of multifaceted pharmacodynamic responses to hypertension interventions

Wang, Q., Gan, J., Wei, K., Berceli, S. A., Gragnoli, C. & Wu, R., Mar 1 2019, In : Drug Discovery Today. 24, 3, p. 883-889 7 p.

Research output: Contribution to journalReview article

Quantitative Trait Loci
Blood Pressure
Hypertension
Pharmaceutical Preparations
Patient Rights