Center for Statistical Genetics

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Research Output 1982 2019

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2019

A Bayesian joint model of recurrent events and a terminal event

Li, Z., Chinchilli, V. & Wang, M., Jan 1 2019, In : Biometrical Journal. 61, 1, p. 187-202 16 p.

Research output: Contribution to journalArticle

Recurrent Events
Joint Model
Bayesian Model
Frailty
Frailty Model
1 Citation (Scopus)

A computational framework to assess genome-wide distribution of polymorphic human endogenous retrovirus-k in human populations

Li, W., Lin, L., Malhotra, R., Yang, L., Acharya, R. & Poss, M., Mar 1 2019, In : PLoS computational biology. 15, 3, e1006564.

Research output: Contribution to journalArticle

Open Access
Retroviridae
Endogenous Retroviruses
human population
Genome
genome
1 Citation (Scopus)

Adapting clinical trial design to maintain meaningful outcomes during a multicenter asthma trial in the precision medicine era

On behalf of the National Heart Lung and Blood Institute's “AsthmaNet”, Feb 1 2019, In : Contemporary Clinical Trials. 77, p. 98-103 6 p.

Research output: Contribution to journalArticle

Precision Medicine
Multicenter Studies
Asthma
Eosinophils
Clinical Trials

A dissection model for mapping complex traits

Sang, M., Shi, H., Wei, K., Ye, M., Jiang, L., Sun, L. & Wu, R., Mar 1 2019, In : Plant Journal. 97, 6, p. 1168-1182 15 p.

Research output: Contribution to journalArticle

Dissection
quantitative trait loci
DNA Shuffling
Genetic Selection
Quantitative Trait Loci

An adaptive multivariate two-sample test with application to microbiome differential abundance analysis

Banerjee, K., Zhao, N., Srinivasan, A., Xue, L., Hicks, S., Middleton, F. A., Wu, R. & Zhan, X., Jan 1 2019, In : Frontiers in Genetics. 10, APR, 350.

Research output: Contribution to journalArticle

Open Access
Microbiota
Validation Studies
Software
Multivariate Analysis
Open Access
Colorectal Surgery
Angiotensins
Acute Kidney Injury
Cohort Studies
Retrospective Studies
5 Citations (Scopus)

Association between DNA methylation in obesity-related genes and body mass index percentile in adolescents

He, F., Berg, A., Imamura, Y., Bixler, E., Fernandez-Mendoza, J., Whitsel, E. A. & Liao, D., Dec 1 2019, In : Scientific reports. 9, 1, 2079.

Research output: Contribution to journalArticle

DNA Methylation
Body Mass Index
Obesity
Genes
Pediatric Obesity
Hormone Replacement Therapy
Coronary Disease
Meta-Analysis
Stroke
Regression Analysis

A unified DNA sequence and non-DNA sequence mapping model of complex traits

Zeng, Y., Zhu, X., Chen, C., Banerjee, K., Sun, L., Yu, W., Zheng, B. & Wu, R., Jan 1 2019, In : Plant Journal. 99, 4, p. 784-795 12 p.

Research output: Contribution to journalArticle

quantitative trait loci
Quantitative Trait Loci
nucleotide sequences
Taxaceae
Gymnosperms

Bayesian multidimensional scaling procedure with variable selection

Lin, L. & Fong, D., Jan 1 2019, In : Computational Statistics and Data Analysis. 129, p. 1-13 13 p.

Research output: Contribution to journalArticle

Variable Selection
Scaling
Dimension Reduction
Side Information
Multivariate Regression

Cardiovascular and Metabolic Risk in Women in the First Year Postpartum: Allostatic Load as a Function of Race, Ethnicity, and Poverty Status

Shalowitz, M. U., Schetter, C. D., Hillemeier, M. M., Chinchilli, V., Adam, E. K., Hobel, C. J., Ramey, S. L., Vance, M. R., O'Campo, P., Thorp, J. M., Seeman, T. E. & Raju, T. N. K., Jan 1 2019, In : American Journal of Perinatology. 36, 10, p. 1079-1089 11 p.

Research output: Contribution to journalArticle

Allostasis
Poverty
Postpartum Period
Breast Feeding
Hispanic Americans

Changes in healthcare expenditures after the autism insurance mandate

Wang, L., Ma, J., Dholakia, R., Howells, C., Lu, Y., Chen, C., Li, R., Murray, M. & Leslie, D., Jan 1 2019, In : Research in Autism Spectrum Disorders. 57, p. 97-104 8 p.

Research output: Contribution to journalArticle

Autistic Disorder
Health Expenditures
Insurance
Delivery of Health Care
Insurance Carriers
1 Citation (Scopus)

Convergent horizontal gene transfer and cross-talk of mobile nucleic acids in parasitic plants

Yang, Z., Wafula, E. K., Kim, G., Shahid, S., McNeal, J. R., Ralph, P. E., Timilsena, P. R., Yu, W. B., Kelly, E. A., Zhang, H., Person, T. N., Altman, N. S., Axtell, M., Westwood, J. H. & Depamphilis, C. W., Jan 1 2019, (Accepted/In press) In : Nature Plants.

Research output: Contribution to journalArticle

parasitic plants
nucleic acids
Cuscuta
Cuscuta campestris
parasites

Covariate Information Matrix for Sufficient Dimension Reduction

Yao, W., Nandy, D., Lindsay, B. G. & Chiaromonte, F., Jan 1 2019, In : Journal of the American Statistical Association.

Research output: Contribution to journalArticle

Sufficient Dimension Reduction
Information Matrix
Covariates
Central Subspace
Reduction Method
1 Citation (Scopus)

Effect of Exercise on Breast Cancer-Related Lymphedema: What the Lymphatic Surgeon Needs to Know

Panchik, D., Masco, S., Zinnikas, P., Hillriegel, B., Lauder, T., Suttmann, E., Chinchilli, V., McBeth, M. & Hermann, W., Jan 1 2019, In : Journal of Reconstructive Microsurgery. 35, 1, p. 37-45 9 p.

Research output: Contribution to journalArticle

Exercise
Practice Guidelines
Meta-Analysis
Qigong
Quality of Life
2 Citations (Scopus)

Estimating the probability of abusive head trauma after abuse evaluation

for the Pediatric Brain Injury Research Network (PediBIRN) Investigators, Feb 1 2019, In : Child Abuse and Neglect. 88, p. 266-274 9 p.

Research output: Contribution to journalArticle

Craniocerebral Trauma
Decision Support Techniques
Critical Care
Logistic Models
Child Abuse
Dementia
Quality of Life
Art
Caregivers
Appointments and Schedules
5 Citations (Scopus)

Exome Chip Meta-analysis Fine Maps Causal Variants and Elucidates the Genetic Architecture of Rare Coding Variants in Smoking and Alcohol Use

CHD Exome+ Consortium, Consortium for Genetics of Smoking Behaviour, Brazel, D. M., Jiang, Y., Hughey, J. M., Turcot, V., Zhan, X., Gong, J., Batini, C., Weissenkampen, J. D., Liu, M. Z., Surendran, P., Young, R., Barnes, D. R., Nielsen, S. F., Rasheed, A., Samuel, M., Zhao, W., Kontto, J., Perola, M. & 32 others, Caslake, M., de Craen, A. J. M., Trompet, S., Uria-Nickelsen, M., Malarstig, A., Reily, D. F., Hoek, M., Vogt, T., Jukema, J. W., Sattar, N., Ford, I., Packard, C. J., Alam, D. S., Majumder, A. A. S., Di Angelantonio, E., Chowdhury, R., Amouyel, P., Arveiler, D., Blankenberg, S., Ferrières, J., Kee, F., Kuulasmaa, K., Müller-Nurasyid, M., Veronesi, G., Virtamo, J., EPIC-CVD Consortium, C., Frossard, P., Nordestgaard, B. G., Saleheen, D., Danesh, J., Butterworth, A. S. & Liu, D., Jun 1 2019, In : Biological Psychiatry. 85, 11, p. 946-955 10 p.

Research output: Contribution to journalArticle

Exome
Meta-Analysis
Smoking
Alcohols
Phenotype

Feature screening in ultrahigh-dimensional varying-coefficient Cox model

Yang, G., Zhang, L., Li, R. & Huang, Y., May 1 2019, In : Journal of Multivariate Analysis. 171, p. 284-297 14 p.

Research output: Contribution to journalArticle

Varying Coefficient Model
Cox Model
Screening
Predictors
Partial Likelihood

Functional data analysis for computational biology

Cremona, M., Xu, H., Makova, K. D., Reimherr, M. L., Chiaromonte, F. & Madrigal, P., Sep 1 2019, In : Bioinformatics (Oxford, England). 35, 17, p. 3211-3213 3 p.

Research output: Contribution to journalArticle

Functional Data Analysis
Computational Biology
Bioinformatics
1 Citation (Scopus)

Functional mapping of N deficiency-induced response in wheat yield-component traits by implementing high-throughput phenotyping

Jiang, L., Sun, L., Ye, M., Wang, J., Wang, Y., Bogard, M., Lacaze, X., Fournier, A., Beauchêne, K., Gouache, D. & Wu, R., Mar 1 2019, In : Plant Journal. 97, 6, p. 1105-1119 15 p.

Research output: Contribution to journalArticle

yield components
Triticum
phenotype
wheat
Quantitative Trait Loci

Impact of AKI on urinary protein excretion: Analysis of two prospective cohorts

Hsu, C. Y., Hsu, R. K., Liu, K. D., Yang, J., Anderson, A., Chen, J., Chinchilli, V. M., Chinchilli, V., Garg, A. X., Hamm, L., Himmelfarb, J., Kaufman, J. S., Kusek, J. W., Parikh, C. R., Ricardo, A. C., Rosas, S. E., Saab, G., Sha, D., Siew, E. D., Sondheimer, J. & 3 others, Taliercio, J. J., Yang, W. & Go, A. S., Jul 1 2019, In : Journal of the American Society of Nephrology. 30, 7, p. 1271-1281 11 p.

Research output: Contribution to journalArticle

Creatinine
Proteinuria
Urine
Proteins
Cohort Studies
Bariatric Surgery
Knee Osteoarthritis
Pain
Weight Loss
Ontario

Linear hypothesis testing for high dimensional generalized linear models

Shi, C., Song, R., Chen, Z. & Li, R., Jan 1 2019, In : Annals of Statistics. 47, 5, p. 2671-2703 33 p.

Research output: Contribution to journalArticle

Linear Hypothesis
Generalized Linear Model
Hypothesis Testing
High-dimensional
Partial
1 Citation (Scopus)

Loss of bronchoprotection with ICS plus LABA treatment, β-receptor dynamics, and the effect of alendronate

AsthmaNet Investigators, Aug 1 2019, In : Journal of Allergy and Clinical Immunology. 144, 2, p. 416-425.e7

Research output: Contribution to journalArticle

Alendronate
Adrenal Cortex Hormones
Adrenergic Receptors
Placebos
Methacholine Chloride

L-statistics of absolute differences for quantifying the agreement between two variables

Tashakor, E. & Chinchilli, V., Jan 2 2019, In : Journal of Biopharmaceutical Statistics. 29, 1, p. 174-188 15 p.

Research output: Contribution to journalArticle

L-statistics
Concordance
Correlation coefficient
Computer Simulation
Robust Estimators

Mapping covariation quantitative trait loci that control organ growth and whole-plant biomass

Gan, J., Cao, Y., Jiang, L. & Wu, R., May 31 2019, In : Frontiers in Plant Science. 10, 719.

Research output: Contribution to journalArticle

Open Access
biomass production
quantitative trait loci
dry matter partitioning
plant organs
inbred lines

Markov models — hidden Markov models

Grewal, J. K., Krzywinski, M. & Altman, N. S., Sep 1 2019, In : Nature methods. 16, 9, p. 795-796 2 p.

Research output: Contribution to journalArticle

Hidden Markov models
2 Citations (Scopus)

Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci

Understanding Society Scientific Group, EPIC-CVD, GSCAN, Consortium for Genetics of Smoking Behaviour, CHD Exome+ consortium, Erzurumluoglu, A. M., Liu, M., Jackson, V. E., Barnes, D. R., Datta, G., Melbourne, C. A., Young, R., Batini, C., Surendran, P., Jiang, T., Adnan, S. D., Afaq, S., Agrawal, A., Altmaier, E., Antoniou, A. C., Asselbergs, F. W., Baumbach, C., Bierut, L., Bertelsen, S. & 31 others, Boehnke, M., Bots, M. L., Brazel, D. M., Chambers, J. C., Chang-Claude, J., Chen, C., Corley, J., Chou, Y. L., David, S. P., de Boer, R. A., de Leeuw, C. A., Dennis, J. G., Dominiczak, A. F., Dunning, A. M., Easton, D. F., Eaton, C., Elliott, P., Evangelou, E., Faul, J. D., Foroud, T., Goate, A., Gong, J., Grabe, H. J., Haessler, J., Haiman, C., Hallmans, G., Hammerschlag, A. R., Harris, S. E., Hattersley, A., Heath, A. & Liu, D., Jan 1 2019, (Accepted/In press) In : Molecular Psychiatry.

Research output: Contribution to journalArticle

Open Access
Genetic Loci
Meta-Analysis
Smoking
Nucleotides
Exome

Methods for the Analysis and Interpretation for Rare Variants Associated with Complex Traits

Weissenkampen, J. D., Jiang, Y., Eckert, S., Jiang, B., Li, B. & Liu, D., Apr 1 2019, In : Current protocols in human genetics. 101, 1, e83.

Research output: Contribution to journalArticle

Exome
Precision Medicine
DNA Sequence Analysis
Sequence Analysis
Meta-Analysis
4 Citations (Scopus)

Mometasone or tiotropium in mild asthma with a low sputum eosinophil level

Lazarus, S. C., Krishnan, J. A., King, T., Lang, J. E., Blake, K. V., Covar, R., Lugogo, N., Wenzel, S., Chinchilli, V., Mauger, D., Dyer, A. M., Boushey, H. A., Fahy, J. V., Woodruff, P. G., Bacharier, L. B., Cabana, M. D., Cardet, J. C., Castro, M., Chmiel, J., Denlinger, L. & 24 others, DiMango, E., Fitzpatrick, A. M., Gentile, D., Hastie, A., Holguin, F., Israel, E., Jackson, D., Kraft, M., LaForce, C., Lemanske, R. F., Martinez, F. D., Moore, W., Morgan, W. J., Moy, J. N., Myers, R., Peters, S. P., Phipatanakul, W., Pongracic, J. A., Que, L., Ross, K., Smith, L., Szefler, S. J., Wechsler, M. E. & Sorkness, C. A., May 23 2019, In : New England Journal of Medicine. 380, 21, p. 2009-2019 11 p.

Research output: Contribution to journalArticle

Mometasone Furoate
Sputum
Eosinophils
Asthma
Placebos

np2QTL: networking phenotypic plasticity quantitative trait loci across heterogeneous environments

Ye, M., Jiang, L., Chen, C., Zhu, X., Wang, M. & Wu, R., Jan 1 2019, In : Plant Journal. 99, 4, p. 796-806 11 p.

Research output: Contribution to journalArticle

Quantitative Trait Loci
phenotypic plasticity
quantitative trait loci
plant adaptation
Plastics

np2QTL: networking phenotypic plasticity quantitative trait loci across heterogeneous environments

Ye, M., Jiang, L., Chen, C., Zhu, X., Wang, M. & Wu, R., Apr 22 2019, In : the Plant Journal.

Research output: Contribution to journalArticle

Open Access

Optical spectroscopy study of Ca3(Ru0.91Mn0.09)2O7 single crystal in high magnetic fields

Xu, X., Peng, J., Zhang, J., Ma, Z., Chen, C., Han, J., Liu, B., Lin, L., Wu, X., Mao, Z., Qu, Z. & Sheng, Z., 2019, In : Science Bulletin. 64, 1, p. 20-25 6 p.

Research output: Contribution to journalArticle

orbitals
single crystals
magnetic fields
spectroscopy
transition metals
Optimal Transport
Cluster analysis
Cluster Analysis
Agglomeration
Partition

Portal nodes screening for large scale social networks

Zhu, X., Chang, X., Li, R. & Wang, H., Apr 1 2019, In : Journal of Econometrics. 209, 2, p. 145-157 13 p.

Research output: Contribution to journalArticle

Node
Autoregression
Social networks
Screening
Coefficients

Predictors of inhaled corticosteroid taper failure in adults with asthma

National Heart, Lung, and Blood Institute Asthmanet, Apr 1 2019, In : Journal of Allergy and Clinical Immunology: In Practice. 7, 4, p. 1335-1337.e3

Research output: Contribution to journalArticle

Adrenal Cortex Hormones
Asthma
6 Citations (Scopus)

Prevalence of metabolic syndrome in veterans with spinal cord injury

Gater, D., Farkas, G. J., Berg, A. & Castillo, C., Jan 2 2019, In : Journal of Spinal Cord Medicine. 42, 1, p. 86-93 8 p.

Research output: Contribution to journalArticle

Veterans
Spinal Cord Injuries
Mid-Atlantic Region
Body Mass Index
Obesity
2 Citations (Scopus)

Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

T2D-Genes Consortium, The MAGIC Investigators, CHD Exome+ Consortium, Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium, EPIC-CVD Consortium, ExomeBP Consortium, Global Lipids Genetic Consortium, GoT2D Genes Consortium, InterAct & ReproGen Consortium, Mar 1 2019, In : Nature Genetics. 51, 3, p. 452-469 18 p.

Research output: Contribution to journalArticle

Body Fat Distribution
Homeostasis
Lipids
Fats
Genes

Reduced bias nonparametric lifetime density and hazard estimation

Berg, A., Politis, D., Suaray, K. & Zeng, H., Jan 1 2019, (Accepted/In press) In : Test.

Research output: Contribution to journalArticle

Hazard
Hazard Rate
Lifetime
kernel
Estimator

Retrovirus insertion site analysis of LGL leukemia patient genomes

Li, W., Yang, L., Harris, R. S., Lin, L., Olson, T. L., Hamele, C. E., Feith, D. J., Loughran, T. P. & Poss, M., Jun 17 2019, In : BMC Medical Genomics. 12, 1, 88.

Research output: Contribution to journalArticle

Open Access
Large Granular Lymphocytic Leukemia
Endogenous Retroviruses
Retroviridae
Genome
Lymphocytes

Risk versus reward: host dependent parasite mortality rates and phenotypes in the facultative generalist Triphysaria versicolor

Honaas, L. A., Jones, S., Farrell, N., Kamerow, W., Zhang, H., Vescio, K., Altman, N. S., Yoder, J. I. & Depamphilis, C. W., Aug 1 2019, In : BMC plant biology. 19, 1, 1 p.

Research output: Contribution to journalArticle

Open Access
parasitic plants
phenotype
parasites
plant architecture
animal communication

Semiparametric regression for measurement error model with heteroscedastic error

Li, M., Ma, Y. & Li, R., May 1 2019, In : Journal of Multivariate Analysis. 171, p. 320-338 19 p.

Research output: Contribution to journalArticle

Heteroscedastic Errors
Semiparametric Regression
Measurement Error Model
Measurement errors
Measurement Error

Sex dimorphism in the distribution of adipose tissue and its influence on proinflammatory adipokines and cardiometabolic profiles in motor complete spinal cord injury

Farkas, G. J., Gorgey, A. S., Dolbow, D. R., Berg, A. & Gater, D., Jul 4 2019, In : Journal of Spinal Cord Medicine. 42, 4, p. 430-436 7 p.

Research output: Contribution to journalArticle

Adipokines
Spinal Cord Injuries
Sex Characteristics
Adipose Tissue
Sex Distribution
1 Citation (Scopus)

Sharpening Jensen's Inequality

Liao, J. J. & Berg, A., Jul 3 2019, In : American Statistician. 73, 3, p. 278-281 4 p.

Research output: Contribution to journalArticle

Jensen's inequality
Power Mean
Moment generating function
Calculus
Form
1 Citation (Scopus)

Statistical methods for evaluating the correlation between timeline follow-back data and daily process data with applications to research on alcohol and marijuana use

Liu, W., Li, R., Zimmerman, M. A., Walton, M. A., Cunningham, R. M. & Buu, A., Jul 1 2019, In : Addictive Behaviors. 94, p. 147-155 9 p.

Research output: Contribution to journalArticle

Cannabis
Statistical methods
Alcohols
Research
Experiments
7 Citations (Scopus)

Suicide among cancer patients

Zaorsky, N., Zhang, Y., Tuanquin, L., Bluethmann, S., Park, H. S. & Chinchilli, V., Dec 1 2019, In : Nature communications. 10, 1, 207.

Research output: Contribution to journalArticle

Suicide
cancer
Epidemiology
Neoplasms
lungs

The Crohn’s disease associated SNP rs6651252 impacts MYC gene expression in human colonic epithelial cells

Matthews, S. M., Eshelman, M. A., Berg, A., Koltun, W. & Yochum, G., Feb 1 2019, In : PloS one. 14, 2, e0212850.

Research output: Contribution to journalArticle

Open Access
Crohn disease
Polymorphism
Gene expression
Crohn Disease
single nucleotide polymorphism

The genomic landscape of crossover interference in the desert tree populus euphratica

Wang, P., Jiang, L., Ye, M., Zhu, X. & Wu, R., Jan 1 2019, In : Frontiers in Genetics. 10, MAY, 440.

Research output: Contribution to journalArticle

Open Access
Populus
Chromosomes
Genome

Ultrahigh dimensional precision matrix estimation via refitted cross validation

Wang, L., Chen, Z., Wang, C. D. & Li, R., Jan 1 2019, (Accepted/In press) In : Journal of Econometrics.

Research output: Contribution to journalArticle

Cross-validation
Spurious correlation
Scenarios
Asset allocation
Finite sample