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Review article
2020

A rewiring model of intratumoral interaction networks

Sang, M., Rice, S., Jiang, L., Liu, X., Gragnoli, C., Belani, C. P. & Wu, R., 2020, In : Computational and Structural Biotechnology Journal. 18, p. 45-51 7 p.

Research output: Contribution to journalReview article

Open Access

Risk factors of perioperative mortality from complicated peptic ulcer disease in Africa: Systematic review and meta-analysis

Peiffer, S., Pelton, M., Keeney, L., Kwon, E. G., Ofosu-Okromah, R., Acharya, Y., Chinchilli, V. M., Soybel, D. I., Oh, J. S. & Ssentongo, P., Feb 17 2020, In : BMJ Open Gastroenterology. 7, 1, e000350.

Research output: Contribution to journalReview article

Open Access
2019

A regulatory network for mir156-spl module in arabidopsis thaliana

Zheng, C., Ye, M., Sang, M. & Wu, R., Dec 2 2019, In : International journal of molecular sciences. 20, 24, 6166.

Research output: Contribution to journalReview article

Open Access

A unified mapping framework of multifaceted pharmacodynamic responses to hypertension interventions

Wang, Q., Gan, J., Wei, K., Berceli, S. A., Gragnoli, C. & Wu, R., Mar 2019, In : Drug Discovery Today. 24, 3, p. 883-889 7 p.

Research output: Contribution to journalReview article

Co-shared genetics and possible risk gene pathway partially explain the comorbidity of schizophrenia, major depressive disorder, type 2 diabetes, and metabolic syndrome

Postolache, T. T., del Bosque-Plata, L., Jabbour, S., Vergare, M., Wu, R. & Gragnoli, C., Apr 2019, In : American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 180, 3, p. 186-203 18 p.

Research output: Contribution to journalReview article

6 Scopus citations

Nutritional status in chronic spinal cord injury: a systematic review and meta-analysis

Farkas, G. J., Pitot, M. A., Berg, A. S. & Gater, D. R., Jan 1 2019, In : Spinal Cord. 57, 1, p. 3-17 15 p.

Research output: Contribution to journalReview article

2 Scopus citations

Risk Factors for Elbow and Shoulder Injuries in Adolescent Baseball Players: A Systematic Review

Norton, R., Honstad, C., Joshi, R., Silvis, M., Chinchilli, V. & Dhawan, A., Mar 1 2019, In : American Journal of Sports Medicine. 47, 4, p. 982-990 9 p.

Research output: Contribution to journalReview article

11 Scopus citations
2018

Mapping genes for drug chronotherapy

Wei, K., Wang, Q., Gan, J., Zhang, S., Ye, M., Gragnoli, C. & Wu, R., Nov 2018, In : Drug Discovery Today. 23, 11, p. 1883-1888 6 p.

Research output: Contribution to journalReview article

3 Scopus citations
2017

Epigenetic game theory: How to compute the epigenetic control of maternal-to-zygotic transition

Wang, Q., Gosik, K., Xing, S., Jiang, L., Sun, L., Chinchilli, V. & Wu, R., Mar 1 2017, In : Physics of Life Reviews. 20, p. 126-137 12 p.

Research output: Contribution to journalReview article

13 Scopus citations

Landscaping Crossover Interference Across a Genome

Sun, L., Wang, J., Sang, M., Jiang, L., Zhao, B., Cheng, T., Zhang, Q. & Wu, R., Oct 2017, In : Trends in Plant Science. 22, 10, p. 894-907 14 p.

Research output: Contribution to journalReview article

2 Scopus citations

Plant grafting: how genetic exchange promotes vascular reconnection

Wang, J., Jiang, L. & Wu, R., Apr 1 2017, In : New Phytologist. 214, 1, p. 56-65 10 p.

Research output: Contribution to journalReview article

22 Scopus citations
2016

Editorial

Li, R., Oct 2016, In : Annals of Statistics. 44, 5, p. 1817-1820 4 p.

Research output: Contribution to journalReview article

Integrating Evolutionary Game Theory into Mechanistic Genotype-Phenotype Mapping

Zhu, X., Jiang, L., Ye, M., Sun, L., Gragnoli, C. & Wu, R., May 1 2016, In : Trends in Genetics. 32, 5, p. 256-268 13 p.

Research output: Contribution to journalReview article

12 Scopus citations
2015

An overview of the prediction of protein DNA-binding sites

Si, J., Zhao, R. & Wu, R., Mar 6 2015, In : International journal of molecular sciences. 16, 3, p. 5194-5215 22 p.

Research output: Contribution to journalReview article

33 Scopus citations

A selective overview of feature screening for ultrahigh-dimensional data

Liu, J. Y., Zhong, W. & Li, R. Z., Oct 29 2015, In : Science China Mathematics. 58, 10

Research output: Contribution to journalReview article

18 Scopus citations

Computational prediction of RNA-binding proteins and binding sites

Si, J., Cui, J., Cheng, J. & Wu, R., Nov 3 2015, In : International journal of molecular sciences. 16, 11, p. 26303-26317 15 p.

Research output: Contribution to journalReview article

30 Scopus citations

Mapping complex traits as a dynamic system

Sun, L. & Wu, R., Jun 1 2015, In : Physics of Life Reviews. 13, p. 155-185 31 p.

Research output: Contribution to journalReview article

23 Scopus citations

Metabolic reprogramming and dysregulated metabolism: Cause, consequence and/or enabler of environmental carcinogenesis?

Brooks Robey, R., Weisz, J., Kuemmerle, N., Salzberg, A. C., Berg, A., Brown, D. G., Kubik, L., Palorini, R., Al-Mulla, F., Al-Temaimi, R., Colacci, A., Mondello, C., Raju, J., Woodrick, J., Ivana Scovassi, A., Singh, N., Vaccari, M., Roy, R., Forte, S., Memeo, L. & 10 others, Salem, H. K., Amedei, A., Hamid, R. A., Williams, G. P., Lowe, L., Meyer, J., Martin, F. L., Bisson, W. H., Chiaradonna, F. & Ryan, E. P., Jun 1 2015, In : Carcinogenesis. 36, p. S203-S231

Research output: Contribution to journalReview article

38 Scopus citations
2014

Systems mapping of genes controlling chemotherapeutic drug efficiency for cancer stem cells

Wu, W., Feng, S., Wang, Y., Wang, N., Hao, H. & Wu, R., Aug 2014, In : Drug Discovery Today. 19, 8, p. 1125-1130 6 p.

Research output: Contribution to journalReview article

4 Scopus citations
2013

A dynamic framework for quantifying the genetic architecture of phenotypic plasticity

Wang, Z., Pang, X., Lv, Y., Xu, F., Zhou, T., Li, X., Feng, S., Li, J., Li, Z. & Wu, R., Jan 1 2013, In : Briefings in bioinformatics. 14, 1, p. 82-95 14 p., bbs009.

Research output: Contribution to journalReview article

14 Scopus citations

Delivering systems pharmacogenomics towards precision medicine through mathematics

Wang, Y., Wang, N., Wang, J., Wang, Z. & Wu, R., Jun 30 2013, In : Advanced Drug Delivery Reviews. 65, 7, p. 905-911 7 p.

Research output: Contribution to journalReview article

8 Scopus citations

Statistical resolution of missing longitudinal data in clinical pharmacogenomics

Wang, Z., Li, H., Wang, J., Li, J. & Wu, R., Jun 30 2013, In : Advanced Drug Delivery Reviews. 65, 7, p. 980-986 7 p.

Research output: Contribution to journalReview article

1 Scopus citations

Stochastic modeling of systems mapping in pharmacogenomics

Wang, Z., Luo, J., Fu, G., Wang, Z. & Wu, R., Jun 30 2013, In : Advanced Drug Delivery Reviews. 65, 7, p. 912-917 6 p.

Research output: Contribution to journalReview article

5 Scopus citations

Systems mapping of metabolic genes through control theory

Liu, G., Kong, L., Wang, Z., Wang, C. & Wu, R., Jun 30 2013, In : Advanced Drug Delivery Reviews. 65, 7, p. 918-928 11 p.

Research output: Contribution to journalReview article

5 Scopus citations

Theoretical Biology and Medical Modelling: Ensuring continued growth and future leadership

Nishiura, H., Rietman, E. A. & Wu, R., Jul 16 2013, In : Theoretical Biology and Medical Modelling. 10, 1, 43.

Research output: Contribution to journalReview article

Variation in the transcriptional response of threatened coral larvae to elevated temperatures

Polato, N. R., Altman, N. S. & Baums, I. B., Mar 1 2013, In : Molecular ecology. 22, 5, p. 1366-1382 17 p.

Research output: Contribution to journalReview article

29 Scopus citations
2012

A pattern-mixture model for haplotype analysis of longitudinal traits with non-ignorable dropout

Li, H. & Wu, R., Jan 1 2012, In : Statistica Sinica. 22, 1, p. 337-357 21 p.

Research output: Contribution to journalReview article

2 Scopus citations

Key observations from the NHLBI Asthma Clinical Research Network

Szefler, S. J., Chinchilli, V. M., Israel, E., Denlinger, L. C., Lemanske, R. F., Calhoun, W. & Peters, S. P., May 2012, In : Thorax. 67, 5, p. 450-455 6 p.

Research output: Contribution to journalReview article

9 Scopus citations
2011

A conceptual framework for pharmacodynamic genome-wide association studies in pharmacogenomics

Wu, R., Tong, C., Wang, Z., Mauger, D., Tantisira, K., Szefler, S. J., Chinchilli, V. M. & Israel, E., Oct 1 2011, In : Drug Discovery Today. 16, 19-20, p. 884-890 7 p.

Research output: Contribution to journalReview article

18 Scopus citations
128 Scopus citations

How to compute which genes control drug resistance dynamics

Guo, Y., Luo, J., Wang, J., Wang, Y. & Wu, R., Apr 1 2011, In : Drug Discovery Today. 16, 7-8, p. 339-344 6 p.

Research output: Contribution to journalReview article

6 Scopus citations

Measures of agreement and concordance with clinical research applications

Landis, J. R., King, T., Choi, J. W., Chinchilli, V. & Koch, G. G., Dec 1 2011, In : Statistics in Biopharmaceutical Research. 3, 2, p. 185-209 25 p.

Research output: Contribution to journalReview article

9 Scopus citations
2010

Designs for linkage analysis and association studies of complex diseases.

Cui, Y., Li, G., Li, S. & Wu, R., Nov 9 2010, In : Methods in molecular biology (Clifton, N.J.). 620, p. 219-242 24 p.

Research output: Contribution to journalReview article

14 Scopus citations

Mapping genes for plant structure, development and evolution: functional mapping meets ontology

He, Q., Berg, A., Li, Y., Vallejos, C. E. & Wu, R., Jan 1 2010, In : Trends in Genetics. 26, 1, p. 39-46 8 p.

Research output: Contribution to journalReview article

30 Scopus citations
2009

Computing genetic imprinting expressed by haplotypes.

Cheng, Y., Berg, A., Wu, S., Li, Y. & Wu, R., 2009, In : Methods in molecular biology (Clifton, N.J.). 573, p. 189-212 24 p.

Research output: Contribution to journalReview article

4 Scopus citations

Genetic dissection of complex endosperm traits

Wang, X., Xu, C., Wu, R. & Larkins, B. A., Jul 1 2009, In : Trends in Plant Science. 14, 7, p. 391-398 8 p.

Research output: Contribution to journalReview article

11 Scopus citations

Network models for dissecting plant development by functional mapping

Wu, S., Yap, J. S., Li, Y., Li, Q., Fu, G., Li, J., Das, K., Berg, A., Zeng, Y. & Wu, R., Sep 1 2009, In : Current Bioinformatics. 4, 3, p. 183-187 5 p.

Research output: Contribution to journalReview article

3 Scopus citations

Penn state hershey - Center for pediatric cardiovascular research: Guest editorial

Ündar, A., Pauliks, L., Clark, J. B., Zahn, J., Rosenberg, G., Kunselman, A. R., Sun, Q., Pekkan, K., Saliba, K., Carney, E., Thomas, N., Freeman, W., Vrana, K., El-Banayosy, A., Ural, S. H., Wilson, R., Umstead, T. M., Floros, J., Phelps, D. S., Weiss, W. & 15 others, Snyder, A., Yang, S., Kimatian, S., Cyran, S. E., Chinchilli, V. M., Guan, Y., Rider, A., Haines, N., Rogerson, A., Alkan-Bozkaya, T., Akcevin, A., Sun, K., Wang, S., Cun, L. & Myers, J. L., Nov 1 2009, In : Artificial organs. 33, 11, p. 883-887 5 p.

Research output: Contribution to journalReview article

4 Scopus citations
2008

Modeling the genetic control of HIV-1 dynamics after highly active antiretroviral therapy

Ma, C. X., Li, Y. & Wu, R., May 1 2008, In : Current Genomics. 9, 3, p. 208-211 4 p.

Research output: Contribution to journalReview article

2 Scopus citations

Rejoinder: One-step sparse estimates in nonconcave penalized likelihood models

Zou, H. & Li, R., Aug 1 2008, In : Annals of Statistics. 36, 4, p. 1561-1566 6 p.

Research output: Contribution to journalReview article

16 Scopus citations
2007

A general quantitative genetic model for haplotyping a complex trait in humans

Wu, S., Yang, J., Wang, C. & Wu, R., Aug 1 2007, In : Current Genomics. 8, 5, p. 343-350 8 p.

Research output: Contribution to journalReview article

8 Scopus citations
14 Scopus citations
39 Scopus citations

Mapping nucleotide sequences that encode complex binary disease traits with HapMap

Cui, Y., Fu, W., Sun, K., Romero, R. & Wu, R., Aug 1 2007, In : Current Genomics. 8, 5, p. 307-322 16 p.

Research output: Contribution to journalReview article

8 Scopus citations

The floral genome: an evolutionary history of gene duplication and shifting patterns of gene expression

Soltis, D. E., Ma, H., Frohlich, M. W., Soltis, P. S., Albert, V. A., Oppenheimer, D. G., Altman, N. S., dePamphilis, C. & Leebens-Mack, J., Aug 1 2007, In : Trends in Plant Science. 12, 8, p. 358-367 10 p.

Research output: Contribution to journalReview article

73 Scopus citations
2006

Clustering periodic patterns of gene expression based on fourier approximations

Kim, B. R., Littell, R. C. & Wu, R., May 1 2006, In : Current Genomics. 7, 3, p. 197-203 7 p.

Research output: Contribution to journalReview article

13 Scopus citations

Detecting sequence-sequence interactions for complex diseases

Lin, M. & Wu, R., Mar 1 2006, In : Current Genomics. 7, 1, p. 59-72 14 p.

Research output: Contribution to journalReview article

8 Scopus citations

Epistatic control of human obesity as revealed by linkage disequilibrium mapping: A report from the NHLBI-sponsored WISE study

Li, H., Wu, R., Lin, M., Terra, S. G., Pepine, C. J., McGorray, S. P., Johnson, B. D. & Johnson, J. A., Nov 1 2006, In : Current Genomics. 7, 7, p. 463-468 6 p.

Research output: Contribution to journalReview article

1 Scopus citations

Opinion: Functional mapping - How to map and study the genetic architecture of dynamic complex traits

Wu, R. & Lin, M., Mar 1 2006, In : Nature Reviews Genetics. 7, 3, p. 229-237 9 p.

Research output: Contribution to journalReview article

229 Scopus citations
2004

Head Injury and Pulmonary Embolism: A Retrospective Report Based on the Pennsylvania Trauma Outcomes Study

Page, R. B., Spott, M. A., Krishnamurthy, S., Taleghani, C., Chinchilli, V. M., Kelly, D. F., Chandler, W. F., Marion, D. W. & Wilberger, J. E., Jan 2004, In : Neurosurgery. 54, 1, p. 143-149 7 p.

Research output: Contribution to journalReview article

23 Scopus citations