Research Output per year
Research Output per year
Organization profile
Organization profile
The Department of Biochemistry and Molecular Biology at Penn State College of Medicine strives to marry the increasingly powerful tools of genomics and computational biology with the classic approaches of biochemistry and molecular biology to reveal fundamental processes of biology and to convert those discoveries into treatments that improve the well-being of patients.
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Dive into the research topics where Department of Biochemistry and Molecular Biology is active. These topic labels come from the works of this organization's members. Together they form a unique fingerprint.
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Profiles
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Cesar Aliaga, MS
- Department of Biochemistry and Molecular Biology - Senior Research Associate
Person: Academic
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Maria Bewley, PhD
- Department of Biochemistry and Molecular Biology - Associate Professor
Person: Academic
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James Broach, PhD
- Department of Biochemistry and Molecular Biology - Distinguished Professor and Chair
- Institute for Personalized Medicine - Director
- Penn State Cancer Institute
- Cancer Institute, Next-Generation Therapies
Person: Academic
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Laura Carrel, MA, PhD
- Department of Biochemistry and Molecular Biology - Associate Professor
- Huck Institutes of the Life Sciences
Person: Academic
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Kun-Ming Chen, PhD, MS
- Department of Biochemistry and Molecular Biology - Associate Professor
- Penn State Cancer Institute
- Cancer Institute, Mechanisms of Carcinogenesis
Person: Academic
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Keith Cheng, MD, PhD
- Department of Pathology and Laboratory Medicine - Distinguished Professor
- Division of Experimental Pathology
- Department of Biochemistry and Molecular Biology - Distinguished Professor
- Department of Pharmacology - Distinguished Professor
- Penn State Cancer Institute
- Huck Institutes of the Life Sciences
- Cancer Institute, Next-Generation Therapies
Person: Academic
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Gary Clawson, MS, PhD, MD
- Department of Pathology and Laboratory Medicine - Professor Emeritus
- Division of Experimental Pathology
- Department of Biochemistry and Molecular Biology - Professor Emeritus
- Penn State Cancer Institute
- Materials Research Institute (MRI)
- Cancer Institute, Next-Generation Therapies
Person: Academic
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Arunangshu Das, MSc, PhD
- Department of Biochemistry and Molecular Biology - Assistant Professor
Person: Academic
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Nikolay Dokholyan, PhD, MS
- Department of Pharmacology - G. Thomas Passananti Professor and Vice Chair for Research
- Department of Biochemistry and Molecular Biology - Professor
- Penn State Neuroscience Institute
- Penn State Cancer Institute
- Cancer Institute, Next-Generation Therapies
Person: Academic
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Keri Donaldson, MD, MS
- Department of Biochemistry and Molecular Biology - Assistant Professor
- Institute for Personalized Medicine
- Department of Public Health Sciences - Assistant Professor
Person: Academic
Research Output
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Selective synthetic augmentation with HistoGAN for improved histopathology image classification
Xue, Y., Ye, J., Zhou, Q., Long, L. R., Antani, S., Xue, Z., Cornwell, C., Zaino, R., Cheng, K. & Huang, X., Jan 2021, In: Medical Image Analysis. 67, 101816.Research output: Contribution to journal › Article › peer-review
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The environmental pollutant and tobacco smoke constituent dibenzo[def,p]chrysene is a co-factor for malignant progression of mouse oral papillomavirus infections
Christensen, N. D., Chen, K. M., Hu, J., Stairs, D. B., Sun, Y. W., Aliaga, C., Balogh, K. K., Atkins, H., Shearer, D., Li, J., Brendle, S. A., Gowda, K., Amin, S., Walter, V., Viscidi, R. & El-Bayoumy, K., Jan 5 2021, In: Chemico-Biological Interactions. 333, 109321.Research output: Contribution to journal › Article › peer-review
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Abdominal pain in quiescent inflammatory bowel disease
Coates, M. D., Johri, A., Gorrepati, V. S., Maheshwari, P., Dalessio, S., Walter, V., Stuart, A., Koltun, W., Bernasko, N., Tinsley, A., Williams, E. D. & Clarke, K., 2020, (Accepted/In press) In: International Journal of Colorectal Disease.Research output: Contribution to journal › Article › peer-review
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Acquired antibody responses against merozoite surface protein-119 antigen during Plasmodium falciparum and P.vivax infections in South Indian city of Mangaluru
Punnath, K., Dayanand, K. K., Midya, V., Chandrashekar, V. N., Achur, R. N., Kakkilaya, S. B., Ghosh, S. K., Kumari, S. N. & Gowda, D. C., 2020, (Accepted/In press) In: Journal of Parasitic Diseases.Research output: Contribution to journal › Article › peer-review
Open Access -
Alteration of CTCF-associated chromatin neighborhood inhibits TAL1-driven oncogenic transcription program and leukemogenesis
Li, Y., Liao, Z., Luo, H., Benyoucef, A., Kang, Y., Lai, Q., Dovat, S., Miller, B., Chepelev, I., Li, Y., Zhao, K., Brand, M. & Huang, S., Apr 6 2020, In: Nucleic acids research. 48, 6, p. 3119-3133 15 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Alternative Splicing of Opioid Receptor Genes Shows a Conserved Pattern for 6TM Receptor Variants
Piltonen, M., Krokhotin, A., Parisien, M., Bérubé, P., Djambazian, H., Sladek, R., Dokholyan, N. V., Shabalina, S. A. & Diatchenko, L., 2020, (Accepted/In press) In: Cellular and Molecular Neurobiology.Research output: Contribution to journal › Article › peer-review
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A master regulator of bacteroides thetaiotaomicron gut colonization controls carbohydrate utilization and an alternative protein synthesis factor
Townsend, G. E., Han, W., Schwalm, N. D., Hong, X., Bencivenga-Barry, N. A., Goodman, A. L. & Groisman, E. A., Jan 1 2020, In: mBio. 11, 1, e03221-19.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
An adjunctive therapy administered with an antibiotic prevents enrichment of antibiotic-resistant clones of a colonizing opportunistic pathogen
Morley, V. J., Kinnear, C. L., Sim, D. G., Olson, S. N., Jackson, L. M., Hansen, E., Usher, G. A., Showalter, S. A., Pai, M. P., Woods, R. J. & Read, A. F., Dec 1 2020, In: eLife. 9Research output: Contribution to journal › Article › peer-review
Open Access -
An Integrated Approach for Preventing Oral Cavity and Oropharyngeal Cancers: Two Etiologies with Distinct and Shared Mechanisms of Carcinogenesis
El-Bayoumy, K., Christensen, N. D., Hu, J., Viscidi, R., Stairs, D. B., Walter, V., Chen, K. M., Sun, Y. W., Muscat, J. E. & Richie, J. P., Aug 1 2020, In: Cancer prevention research (Philadelphia, Pa.). 13, 8, p. 649-660 12 p.Research output: Contribution to journal › Review article › peer-review
2 Scopus citations -
An integrative ENCODE resource for cancer genomics
Zhang, J., Lee, D., Dhiman, V., Jiang, P., Xu, J., McGillivray, P., Yang, H., Liu, J., Meyerson, W., Clarke, D., Gu, M., Li, S., Lou, S., Xu, J., Lochovsky, L., Ung, M., Ma, L., Yu, S., Cao, Q., Harmanci, A. & 38 others, , Dec 1 2020, In: Nature communications. 11, 1, 3696.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations
Projects
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Translational Studies on Electronic Cigarette-derived Oxidants and their Long-term Pulmonary Effects
National Heart, Lung, and Blood Institute
7/1/20 → 6/30/21
Project: Research project
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High-throughput surveillance of gut mucosal polysaccharides
National Institute of Allergy and Infectious Diseases
2/1/20 → 1/31/21
Project: Research project
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The role of DNA damage tolerance pathways in human cells
Moldovan, G., Bielinsky, A. K., MOLDOVAN, G. L. & Bielinsky, A. K.
National Institute of General Medical Sciences
8/14/19 → 5/31/21
Project: Research project
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Metabolic activation of nitroarenes and Nrf2-Keap1
El-Bayoumy, K., Penning, T., El-Bayoumy, K. & Penning, T.
National Institute of Environmental Health Sciences
5/8/19 → 4/30/21
Project: Research project
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Chemoprevention by black raspberry in oral cancer induced by DB[a,l]P in mice
El-Bayoumy, K. & EL-BAYOUMY, K. E.
4/1/13 → 1/31/21
Project: Research project
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Genotoxicity and Repair of Tobacco-Specific Nitrosamine DNA Adducts
Spratt, T., SPRATT, T., SPRATT, T. E. & SPRATT, T.
National Institute of Environmental Health Sciences
7/20/12 → 5/31/21
Project: Research project
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Cellular responses to exogenous and endogenous assault
National Institute of Environmental Health Sciences
7/1/19 → 6/30/20
Project: Research project
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Cancer induction in the ovary by an environmental pollutant, dibenzo[a,l]pyrene
Chen, K., Chen, K. M. & Chen, K. M.
National Institute of Environmental Health Sciences
9/15/13 → 8/31/17
Project: Research project
Activities
- 3 Oral presentation
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Morphometric phenomics and Cross-Atlas Registration of Virtual 3D soft tissue microCT images of Zebrafish
Keith Cheng (Speaker), Y Ding (Speaker), AY Lin (Speaker), M Yakovlev (Speaker), D Vanselow (Speaker), X Xin (Speaker), S Katz (Speaker), D Vanselow (Speaker) & PJ La Riviere (Speaker)
Jul 5 2017Activity: Talk types › Oral presentation
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From Morphology to Math: Using whole zebrafish to create the engineering and computational infrastructure for Microanatomic Phenomics
Keith Cheng (Speaker), Y Ding (Speaker), SR Katz (Speaker), AY Lin (Speaker), D van Rossum (Speaker) & D Vanselow (Speaker)
Sep 27 2017Activity: Talk types › Oral presentation
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Motivations and Potential for a 3D Image Informatics for Histopathology (Panel Discussion)
Keith Cheng (Speaker)
Nov 4 2017Activity: Talk types › Oral presentation
Prizes
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Distinguished Educator Award
Ghahramani, Nasrollah (Recipient), Eckert, Kristin (Recipient), Hennrikus, William (Recipient) & Wojnar, Margaret "Peg" (Recipient), 2015
Prize
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Distinguished Educator Award
Caputo, Gregory (Recipient), Jeffries, Graham (Recipient) & Keil, Ralph (Recipient), 2006
Prize
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Michael Hooker Distinguished Professor in Biochemistry and Biophysics
Dokholyan, Nikolay (Recipient), 2013
Prize
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Outstanding Collaborative Research Award
El-Bayoumy, Karam (Recipient), Manni, Andrea (Recipient), Richie, John (Recipient), Liao, Jiangang (Jason) (Recipient), Vanden Heuvel, John Patrick (Recipient), Demers, Laurence (Recipient), Dillard, James (Recipient) & Rogers, Connie Jo (Recipient), 2016
Prize
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