Department of Biochemistry and Molecular Biology

  • United States

Organization profile

Organization profile

The Department of Biochemistry and Molecular Biology at Penn State College of Medicine strives to marry the increasingly powerful tools of genomics and computational biology with the classic approaches of biochemistry and molecular biology to reveal fundamental processes of biology and to convert those discoveries into treatments that improve the well-being of patients.

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    No photo of Cesar Aliaga

    Cesar Aliaga, MS

    Person: Academic

    No photo of Maria Bewley
    No photo of Paula Dalessio
    No photo of Arunangshu Das

    Research Output

    Alteration of CTCF-associated chromatin neighborhood inhibits TAL1-driven oncogenic transcription program and leukemogenesis

    Li, Y., Liao, Z., Luo, H., Benyoucef, A., Kang, Y., Lai, Q., Dovat, S., Miller, B., Chepelev, I., Li, Y., Zhao, K., Brand, M. & Huang, S., Apr 6 2020, In : Nucleic acids research. 48, 6, p. 3119-3133 15 p.

    Research output: Contribution to journalArticle

    Open Access
  • A master regulator of bacteroides thetaiotaomicron gut colonization controls carbohydrate utilization and an alternative protein synthesis factor

    Townsend, G. E., Han, W., Schwalm, N. D., Hong, X., Bencivenga-Barry, N. A., Goodman, A. L. & Groisman, E. A., Jan 1 2020, In : mBio. 11, 1, e03221-19.

    Research output: Contribution to journalArticle

    Open Access
  • Assessing constituent volumes and morphology of bovine casein micelles using cryo-electron tomography

    Hettiarachchi, C. A., Swulius, M. T. & Harte, F. M., May 2020, In : Journal of dairy science. 103, 5, p. 3971-3979 9 p.

    Research output: Contribution to journalArticle

  • Open Access
  • Cellular signaling and epigenetic regulation of gene expression in leukemia

    Gowda, C., Song, C., Ding, Y., Iyer, S., Dhanyamraju, P. K., McGrath, M., Bamme, Y., Soliman, M., Kane, S., Payne, J. L. & Dovat, S., Jan 2020, In : Advances in Biological Regulation. 75, 100665.

    Research output: Contribution to journalReview article

    Open Access
  • 2 Scopus citations

    Clinical and Genetic Factors Associated With Complications After Crohn's Ileocolectomy

    Kline, B. P., Weaver, T., Brinton, D. L., Deiling, S., Yochum, G. S., Berg, A. S. & Koltun, W. A., Mar 1 2020, In : Diseases of the colon and rectum. 63, 3, p. 357-364 8 p.

    Research output: Contribution to journalArticle

  • Clinical features and haematological parameters among malaria patients in Mangaluru city area in the southwestern coastal region of India

    Punnath, K., Dayanand, K. K., Chandrashekar, V. N., Achur, R. N., Kakkilaya, S. B., Ghosh, S. K., Mukhi, B., Midya, V., Kumari, S. N. & Gowda, D. C., Mar 1 2020, In : Parasitology Research. 119, 3, p. 1043-1056 14 p.

    Research output: Contribution to journalArticle

  • De novo resonance assignment of the transmembrane domain of LR11/SorLA in E. coli membranes

    Ding, X., Fu, R. & Tian, F., Jan 2020, In : Journal of Magnetic Resonance. 310, 106639.

    Research output: Contribution to journalArticle

  • Design, synthesis characterization and biological evaluation of novel multi-isoform ALDH inhibitors as potential anticancer agents

    Dinavahi, S. S., Gowda, R., Bazewicz, C. G., Battu, M. B., Lin, J. M., Chitren, R. J., Pandey, M. K., Amin, S., Robertson, G. P. & Gowda, K., Feb 1 2020, In : European Journal of Medicinal Chemistry. 187, 111962.

    Research output: Contribution to journalArticle

  • Projects

  • Novel Nanoparticle Therapy for Pancreatic Cancer

    Kester, M. & Matters, G.

    National Cancer Institute


    Project: Research project

  • Structural studies of tight junction proteins

    Flanagan, J.


    Project: Research project

  • Activities

    • 3 Oral presentation

    From Morphology to Math: Using whole zebrafish to create the engineering and computational infrastructure for Microanatomic Phenomics

    Keith Cheng (Speaker), , Y Ding (Speaker), , SR Katz (Speaker), , AY Lin (Speaker), , D van Rossum (Speaker), & D Vanselow (Speaker)

    Sep 27 2017

    Activity: Talk typesOral presentation

    Morphometric phenomics and Cross-Atlas Registration of Virtual 3D soft tissue microCT images of Zebrafish

    Keith Cheng (Speaker), , Y Ding (Speaker), , AY Lin (Speaker), , M Yakovlev (Speaker), , D Vanselow (Speaker), , X Xin (Speaker), , S Katz (Speaker), , D Vanselow (Speaker), & PJ La Riviere (Speaker)

    Jul 5 2017

    Activity: Talk typesOral presentation


    40 Under 40

    Festa, Fernanda (Recipient), 2013

    Prize: Honorary award

    Outstanding Collaborative Research Award

    El-Bayoumy, Karam (Recipient), Manni, Andrea (Recipient), Richie, John (Recipient), Liao, Jiangang (Jason) (Recipient), Vanden Heuvel, John Patrick (Recipient), Laurence Demers (Recipient), Dillard, James (Recipient) & Rogers, Connie Jo (Recipient), 2016