Department of Biochemistry and Molecular Biology

  • United States

Projects 1981 2023

Filter
Finished
Finished
Adenocarcinoma
Actins
Neoplasm Metastasis
Cell Movement
Pancreatic Stellate Cells
Environmental Pollutants
Ovarian Neoplasms
Ovary
DNA Adducts
Smoke
Cholecystokinin B Receptor
Pancreatic Neoplasms
Gastrins
Nucleotide Aptamers
Growth

Novel Nanoparticle Therapy for Pancreatic Cancer

Matters, G., Kester, M. & Kester, M.

National Institutes of Health

3/19/132/28/19

Project: Research project

Pancreatic Neoplasms
Nanoparticles
Neoplasms
Adenocarcinoma
Therapeutics
Tight Junction Proteins
Tight Junctions
Occludin
Herpes Zoster
Zonula Occludens-1 Protein
DNA Repair
Carcinogens
DNA Adducts
Tobacco
Lung Neoplasms
Lysine
Corpus Striatum
Glutaryl-CoA Dehydrogenase
Homoarginine
Brain Injuries
Capsid
Virion
Capsid Proteins
Retroviridae
Life Cycle Stages
Catenins
Carcinogenesis
Growth
Colorectal Neoplasms
Intestines
X Chromosome Inactivation
Genes
Insulator Elements
Mammals
Chromosomes
Medicine
Nuclear magnetic resonance
Spectrometers
Proteins
Biochemistry

Chemistry of mutagenesis

Spratt, T.

National Institutes of Health

8/1/057/31/06

Project: Research project

Mutagenesis
DNA
DNA-Directed DNA Polymerase
Carcinogens
Nucleotides
Transforming Growth Factor beta
Ovarian Neoplasms
Dyneins
Growth
Phenotype
Microtubules
Transforming Growth Factor beta
Dyneins
Ovarian Neoplasms
Intercellular Signaling Peptides and Proteins
Transforming Growth Factor beta
Colonic Neoplasms
Neoplasms
Epithelial Cells
Growth
Carrier Proteins
Lipids
Protein folding
Nuclear magnetic resonance
Protons
Chondroitin Sulfates
Malaria
Mothers
Parasites
Placenta
ATP-Dependent Proteases
Adenosine Triphosphatases
Proteolysis
Proteins
Endopeptidase Clp

PRINCIPAL NIH RESEARCH RESOURCE X RAY BEAMLINE AT NSLS: WIGGLER BEAMLINE X25

Flanagan, J., Phillips, W., Berendzen, J., Moore, P. B., Berman, L., Ealick, S., Capel, M., Ruiming, X., Reinherz, E., Terwilliger, T. O. M., Ellenberger, T. E., Sweet, R., Lewis, H. A. L., Sanghani, P., Ohlendorf, D., Chen, L. I. N., Mariuzza, R., Bahnson, B., Beese, L., Hill, C. P., Churchill, M., Doublie, S., van Roey, P., Brown, B. A., Patel, D., Crane, B., Lu, Y. I., Wolberger, C., Ha, Y. A., Honglin, L., Kantrowitz, E., Lambright, D., Kull, F., Becker, M., Amzel, L. M., Reinisch, K., Steitz, T. A., Crane, A., Gouaux, J. E., MacKinnon, R., Schneider, D. K., Swaminathan, S., Robinson, H., Gehring, K., Marcotrigiano, J., Quan, H., Leahy, D., Agbandje-McKenna, M., Stock, A. M., Bohm, A. A., Sondek, J., Muniz, J. R. C., Lawson, C., Marmorstein, R., Varughese, K., Wang, J., Wucherpfennig, K., Richter-Addo, G. B., Dashuang, S., Izard, T., Parry, C., Pollard, T. D., Boriack-Sjodin, A., Kong, X., Silvaggi, N., Kissinger, C., Schulman, B., Neiditch, M., Coulombe, R., Lolis, E., Ferguson, K., Clarke, T., Birrane, G., Verdine, G., Cygler, M., Murakami, K., Bruner, S., Hengming, K., Parris, K. D., Arnold, E. D., Strobel, S., Sygusch, J., Ippolito, J., Zhao, Y., Mallett, T. C., Williams, L. D., Cordes, M., Blacklow, S. C., Jianhua, F., Soares, A. S., Braddock, D., Colman, P., Zhaohui, X., McDonough, M., Kobe, B., Yili, L., Gallagher, T., Morstein, R., Delbaere, L., Paetzel, M. W., Loll, P., Samanta, U., Mariuzza, R., Moore, P. B., Cohen, C., Rould, M., van Den Akker, F., Huang, Z., Merithew, E., Héroux, A., Schlessinger, J., Berman, L. E., Jayaraman, S., Yigong, S., Hill, C. P., Birktoft, J., Hong, L., Junop, M., Almo, S. C., Martucci, W. E., Howell, P. L., Song, J., Quan, H., Zhao, R. U. I., Royer, W., Fu, D. A. X., Wang, Z., Hunt, J. F., Schroeder, S., Kielkopf, C., Vivien, Y., Kissinger, C., Bohm, A. A., Vicens, C. N., Wucherpfennig, K., Morais Cabral, J., Ha, Y. A., Blaber, M., Pata, J., Radisky, E., Bussiere, D., Reinisch, K., Hart, P. J., Allen, K. N., Vedula, L. S., Blobel, G., Schindelin, H., Zhou, M., Buchanan, S. K., Wang, Q. I., Eckenroth, B., Zhou, Z., Simmons, C. R., Lowther, W. T., Gallagher, D., Zhaohui, X., Krasilnikov, A. S., Robinson, V., Silvaggi, N., Park, R., Huang, M., Hughson, F., McMillan, M., Agbandje-McKenna, M., Lawson, C., Allen, C., Hollis, T., vandenberg, L. N., Anderson, A. C., Stern, L., Zongchao, J., Tang, L., Joseph, L., Parsons, J., Christopher Charles, L., Tremblay, L., Neiditch, M., Xiong, Y., Acharya, R., Modis, Y., Jiang-Yong, M., Furukawa, H., Aggarwal, A. K., Orville, A., Khangulov, S., Morrison, J., Eathiraj, S., Z Helen, W., Boudker, O., Jiang, J., Yuan, Y. U., Sanghani, P., Almo, S. C., Czyzewski, B. K., Soares, A. S., Quan, H., Pavletich, N., Beglova, N., Jogl, G., Akey, C., Stock, A. M., Long, S. B., Boriack-Sjodin, P., Riedl, S., Richter-Addo, G. B., Pata, J., Oldfield, E., Wuxian, S., Lolis, E., Heldwein, E., Schiffer, C. A., Joshua, L., Howell, P. L., Garcia-Diaz, M., MacKinnon, R., McKeever, B. M., Huang, Z., Blaber, M., Radisky, E., Pascal, J., Page, R., Sliz, P., vandemark, A. P., Smith, P. B., Reinisch, K., Christensen, H. E., Jian, H., Schlessinger, J., Mariuzza, R., Allen, K., Bowman, G. D., Mangel, W. F., Hardy, J., Vedula, L. S., Feklistov, A., Bing, H., Seeliger, M. A., Armache, K. J., Steitz, T. A., Bruner, S., Everse, S., Huang, M., Sherman, D., Bohm, A. A., Hubbard, S. R., Blobel, G., Nimigean, C., Hang, S., Lawson, C., Lu, Y. I., Simanshu, D., Fromme, J. C., Gerratana, B., Serganov, A., Serganov, A., Jiang, J., Goldberg, J., Liu, C., Smith, P., Liu, C. & Miller, C.

National Institutes of Health

9/30/986/30/13

Project: Research project

proteinases
protein metabolism
adenosinetriphosphatase
degradation
Escherichia coli
molecular genetics
anesthetics
genetic techniques and protocols
yeasts
ubiquitin

GLYCOBIOLOGY OF THE MALARIA PARASITE TMP PILOT NIAID

Gowda, C. & Davidson, E. A.

National Institutes of Health

1/15/9812/31/18

Project: Research project

Malaria
Parasites
Innate Immunity
Glycomics
Cerebral Malaria
Mutagenesis
DNA
Carcinogens
DNA-Directed DNA Polymerase
DNA Polymerase I

MASS SPECTROMETRY RESOURCE FOR BIOLOGY AND MEDICINE

Gowda, C., Rosenberry, T., Case, S., Roberts, D., Newberg, D., Mabrouk, P. A. M., Harn, D., Davidson, E., Lucas, J., Findeis, M., Khorana, H., Walker, G., Turco, S., Jungalwala, F., Drazen, J., Halsall, H., Daniel, P., Cantor, C., Plummer, T., Hakomori, S., Lippard, S., Blithe, D., Walker, G., McCluer, R., Renkonen, O., Kuliopulos, A., Gribble, G., Reinherz, E., Costello, C. E., Farb, D. H., Botten, D., Mabrouk, P., Perreault, H., Laursen, R., Chatterjee, S., Rothschild, K., Seyfried, T., Panjwani, N., Codington, J., Davies, G., Park, H., Cabib, E., Murphy, J., Corey, E., Lansbury, P., Hague, C., Corley, R., Kuliopoulos, A., Meier, W., Setlow, P., Matta, K., Yohe, H., Eberlein, T., Loscalzo, J., Li, K., Hoch, J., Skinner, M., Porcelli, S., McKnight, C. J., Comenzo, R., Newburg, D., Shipley, G., Jarroll, E., Boyd, N., Francesconi, L., Parks, J., van Dijk, W., Sipe, J., Walsh, M., Reinhold, B., Zipser, B., Han, M., Ole, J., Dunlap, J., Reinhold, V., Davies, T., Mirochnick, M., Zopf, D., Wasfi, S., Lamkin, M., Petsko, G., Contreras, R., Schachter, H., Redmond, R., Denis, G., Szostak, J., Chan, S., Klibanov, A., Kuhns, W., Akey, C., Popham, D., Seaton, B., Walsh, C., Koul, O., Rice, P. A., Abeijon, C., Salant, D., Kirschner, D., Vairavamurthy, A., Preti, G., Hearn, M., Snook, M., Fine, R., Holick, M., Lippard, S., Jacobsen, D. W., Hamilton, J. A., Abraham, C., Stone, P. J., Mabrouk, P., Allen, K. N., Russick, S., Lansbury, P., Lafyatis, R., [No Value], J. O., Small, D., Head, J., Olejnik, J., Berg, E. A., Brenner, M., Lippard, S., Rauch, J., Park, H., Pilch, P., Altland, K., Johnson, R., Berman, J., Lansbury, P., Kandror, K. V., Sherr, D., Lee-Parsons, C. W., Zhang, Y., O'Connor, G., Liao, R., Fine, R., McMahon Pratt, D., Jacobsen, D. W., Hansen, U., Saxena, B. B., Murray, A., Whitesides, G., Murphy, J. R., Taccioli, G., Juanherrera, D., Nugent, M., Khorana, H. G., Kukuruszinska, M., Chui, D. H., Leeman, S., Herscovitz, H., Reddy, R. A. J., Robbins, P., Hirschberg, C. B., Cipollo, J., Huber, B. T., Alexander, A., Oppenheim, F., Zannis, V., Tung-Tien, S., O'Connor, P. B., Joshi, L., Denis, G., Skinner, M., Lencer, W., Connors, L. H., Cohen, R., Singh, B. N., Moody, D., Jianming, H., Zaia, J., Kehlbeck, J., Lee, K., Chen, K., Loscalzo, J., Spencer, J., Amar, S., Kaye, K., Russek, S. J., Kirschner, D., Atkinson, D., Freedman, J., Darby, C., Wilson, I., Hodgkin, J., Newburg, D. S., Klings, E., Abraham, C., Samuelson, J. C., Trinkaus-Randall, V., Rothblum, L., Garvas, H., Freeze, H., Yamin, R., Chen, X. I., Xiao, J., Sanjay, R., McClellan, J., Pilch, P., Pandey, A., Powell, B., Robinson, A., Chee Chew, L., Kukuruzinska, M., Merlini, G., Feelisch, M., Steere, A., Sherman, M., McComb, M., Matson, W., Heeren, R. O. N., Kahn, B., Lerner, A., Seldin, D., Aikawa, E., Goldstein, L. E., Longas, M., Sackstein, R., Nicastro, D., Prusiner, S., Lin, C., Xiao, Z., Mathieu, C., Merrill, A. H., Goldstein, L., Xingbin, A., Baird, B., Goldberg, B., Banerjee, D., Nugent, M., Sharon, J., Chamot-Rooke, J., Polgar, P. R., Francoleon, D., Malmstrom, J. A., Rahimi, N., Harris, D. R., Eichler, F., Gummuluru, S., Pinghua, L., Birolo, L., Sahin-Toth, M., Sherr, D., Singh, B., Erickson, K., Conaway, M., Jones, C. & Burke, P.

National Institutes of Health

7/1/968/9/12

Project: Research project

Mucins
Bioactivity
Galactosidases
Hexoses
Cells
Escherichia coli
Proteins
Protein Folding
Site-Directed Mutagenesis
Transforming Growth Factor beta
Research Personnel
Cellular Structures
Growth
Cell Cycle
Colonic Neoplasms
Intercellular Signaling Peptides and Proteins
Colon
ras Genes
Carcinoma
yeasts
loci
Heterochromatin
chromatin
Yeasts
Colon
Transforming Growth Factor beta
Protein S
Colonic Neoplasms
Carcinoma
Cysteine
Guanine
Protonation
DNA
Substrates
Chromosome Segregation
Eukaryotic Cells
Cell Cycle
Plasmids
Research
Transforming Growth Factor beta
Colon
Carcinoma
Growth
Signal Transduction

VIRAL AND CELLULAR ONCOGENES--MECHANISM OF ACTION

Broach, J., Levine, A., Shenk, T., Zakian, V. A., Schupbach, G. M., Schwarzbauer, J. & Wieschaus, E.

National Institutes of Health

7/1/862/28/07

Project: Research project

Ceramides
Yeasts
Signal Transduction
Growth
nutrient availability

AUTOMATED PEPTIDE SYNTHESIS AND PURIFICATION

Broach, J. & Carlson, G. A.

National Institutes of Health

6/1/868/31/94

Project: Research project

Peptides
Sex Determination Analysis
Research
Escherichia coli
Tumor Suppressor Protein p53
Genetic Recombination
Yeasts
Ribosomal DNA
Multigene Family
Genes
Oncogenes
Yeasts
Alleles
Lethal Genes
Genes

ONCOLOGY: MOLECULAR BASIS OF CANCER

Broach, J. & Levine, A.

National Institutes of Health

7/1/856/30/12

Project: Research project

Neoplasms
Research
Developmental Biology
Mentors
Translational Medical Research
Plasmids
Yeasts
Gene Expression
Proteins
Genetic Recombination
Saccharomyces
yeasts
loci
genes
cells
1-nitropyrene
Breast Neoplasms
DNA Adducts
Breast
Carcinogens

EXPERIMENTAL TOBACCO CARCINOGENESIS

El-Bayoumy, K., Prokopczyk, B., Hecht, S., Silverman, J., Lavoie, E., Haley, N., Rivenson, A. S., Brunnemann, K. & Hoffman, D.

National Institutes of Health

6/15/811/31/97

Project: Research project

Tobacco
Amines
Smoking
Smoke
Smokeless Tobacco