Department of Cellular and Molecular Physiology

  • United States

Organization profile

Organization profile

Research Interests

Fingerprint The fingerprint is based on mining the text of the scientific documents related to the associated persons. Based on that an index of weighted terms is created, which defines the key subjects of research unit

Proteins Medicine & Life Sciences
Skeletal Muscle Medicine & Life Sciences
Rats Chemical Compounds
Polyamines Medicine & Life Sciences
Liver Medicine & Life Sciences
Ornithine Decarboxylase Medicine & Life Sciences
Phosphorylation Medicine & Life Sciences
Insulin Medicine & Life Sciences

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Profiles

Photo of Alistair Barber
19892018
Photo of Sarah Bronson

Sarah Bronson, PhD

Person: Academic

19912017
No photo of Vincent Chau
19672017
No photo of Michael Dennis
20072019
Photo of Donald Gill
19812020

Research Output 1965 2019

A calcium/cAMP signaling loop at the ORAI1 mouth drives channel inactivation to shape NFAT induction

Zhang, X., Pathak, T., Yoast, R., Emrich, S., Xin, P., Nwokonko, R. M., Johnson, M., Wu, S., Delierneux, C., Gueguinou, M., Hempel, N., Putney, J. W., Gill, D. & Trebak, M., Dec 1 2019, In : Nature communications. 10, 1, 1971.

Research output: Contribution to journalArticle

Open Access
Calcium Signaling
mouth
deactivation
Mouth
calcium

Anti-Inflammatory Effect of Surfactant Lipid in the Vaginal Mucosa: A Pilot Study

Macneill, C., De Guzman, G. S., Lupo, K., Umstead, T., Phelps, D. & Floros, J., Jan 1 2019, In : Journal of Lower Genital Tract Disease. 23, 1, p. 71-74 4 p.

Research output: Contribution to journalArticle

Surface-Active Agents
Mucous Membrane
Anti-Inflammatory Agents
Lipids
Cytokines

A “Connexin” Responsible for the Fatal Attraction of Cancer to Bone

Waning, D., Guise, T. A. & Mohammad, K. S., Jan 8 2019, In : Cell Metabolism. 29, 1, p. 6-8 3 p.

Research output: Contribution to journalShort survey

Bone Neoplasms
Connexins
Bone and Bones
Neoplasm Metastasis
Neoplasms
2 Citations (Scopus)

Calcium signalling in T cells

Trebak, M. & Kinet, J. P., Mar 1 2019, In : Nature Reviews Immunology. 19, 3, p. 154-169 16 p.

Research output: Contribution to journalReview article

Calcium Signaling
T-Lymphocytes
Immunity
Cell Membrane
Lymphocytes

Closing the therapeutic loop

Campbell, K. S., Yengo, C., Lee, L. C., Kotter, J., Sorrell, V. L., Guglin, M. & Wenk, J. F., Mar 15 2019, In : Archives of Biochemistry and Biophysics. 663, p. 129-131 3 p.

Research output: Contribution to journalReview article

Therapeutics

Converter domain mutations in myosin alter structural kinetics and motor function

Gunther, L. K., Rohde, J. A., Tang, W., Walton, S. D., Unrath, W. C., Trivedi, D. V., Muretta, J. M., Thomas, D. D. & Yengo, C., Jan 1 2019, In : Journal of Biological Chemistry. 294, 5, p. 1554-1567 14 p.

Research output: Contribution to journalArticle

Myosins
Mutation
Kinetics
Adenosine Triphosphatases
Conformations

Cross-talk between N-terminal and C-terminal domains in stromal interaction molecule 2 (STIM2) determines enhanced STIM2 sensitivity

Emrich, S. M., Yoast, R. E., Xin, P., Zhang, X., Pathak, T., Nwokonko, R., Gueguinou, M. F., Subedi, K. P., Zhou, Y., Ambudkar, I. S., Hempel, N., Machaca, K., Gill, D. & Trebak, M., Jan 1 2019, In : Journal of Biological Chemistry. 294, 16, p. 6318-6332 15 p.

Research output: Contribution to journalArticle

Molecules
Chemical activation
Clustered Regularly Interspaced Short Palindromic Repeats
Cell Membrane
Stromal Interaction Molecule 2

Differential Effects of Human SP-A1 and SP-A2 on the BAL Proteome and Signaling Pathways in Response to Klebsiella pneumoniae and Ozone Exposure

Wang, G., Umstead, T. M., Hu, S., Mikerov, A. N., Phelps, D. & Floros, J., Jan 1 2019, In : Frontiers in immunology. 10, 1 p.

Research output: Contribution to journalArticle

Open Access
Ozone
Klebsiella pneumoniae
Bronchoalveolar Lavage
Proteome
varespladib methyl

Dust mite induces leukocyte exosomes with proinflammatory effects toward airway epithelial cells

Lambert, K. A., Hsu, M. H., Laryea, Z. C., Zhao, Y., Roff, A. N., Sundstrom, J. & Ishmael, F., Jan 1 2019, In : Journal of Allergy and Clinical Immunology.

Research output: Contribution to journalArticle

Exosomes
Mites
Dust
Leukocytes
Epithelial Cells

Excess Dietary Zinc Intake in Neonatal Mice Causes Oxidative Stress and Alters Intestinal Host–Microbe Interactions

Podany, A., Rauchut, J., Wu, T., Imamura, Y., Wright, J., Lamendella, R., Soybel, D. & Kelleher, S. L., Feb 1 2019, In : Molecular Nutrition and Food Research. 63, 3, 1800947.

Research output: Contribution to journalArticle

Zinc
neonates
Oxidative Stress
oxidative stress
zinc

Projects 1975 2023

Neoplasm Metastasis
Actin Cytoskeleton
Neoplasms
AMP-Activated Protein Kinases
fascin
Microvessels
Permeability
Reactive Oxygen Species
Nitric Oxide
Peroxynitrous Acid
MicroRNAs
Muscle Cells
Blood Vessels
Ion Channels
Cardiac Myocytes
Cardiac Myosins
Myosins
Cardiomyopathies
Mutation
Ventricular Myosins
Platinum
Ovarian Neoplasms
Nucleotides
Neoplastic Stem Cells
Mentors
90-kDa Ribosomal Protein S6 Kinases
Chronic Renal Insufficiency
Low Density Lipoprotein Receptor-Related Protein-1
Kidney
Fibrosis
Physiological Adaptation
Students
Education
Research
Precision Medicine
Leukotriene C4
Smooth Muscle
Asthma
Ovalbumin
Airway Obstruction
Melanoma
Neoplasm Metastasis
Calcium
Neoplasms
Basement Membrane
Vascular Smooth Muscle
Smooth Muscle Myocytes
Smooth Muscle
Vascular Diseases
Hypertension