Department of Cellular and Molecular Physiology

  • United States

Organization profile

Organization profile

Research Interests

Fingerprint The fingerprint is based on mining the text of the scientific documents related to the associated persons. Based on that an index of weighted terms is created, which defines the key subjects of research unit

Proteins Medicine & Life Sciences
Rats Chemical Compounds
Skeletal Muscle Medicine & Life Sciences
Polyamines Medicine & Life Sciences
Animals Chemical Compounds
Liver Medicine & Life Sciences
Phosphorylation Medicine & Life Sciences
Insulin Medicine & Life Sciences

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Profiles

Photo of Samina Alam
19962018
Photo of Alistair Barber
19892018
Photo of Sarah Bronson

Sarah Bronson, PhD

Person: Academic

19912017
No photo of Vincent Chau
19752017
No photo of Michael Dennis
20072018
Photo of Donald Gill
19812020

Research Output 1965 2018

Acute alcohol prevents the refeeding-induced decrease in autophagy but does not alter the increased protein synthetic response in heart

Mekheal, M., Steiner, J. L. & Lang, C. H., Dec 1 2018, In : Alcohol. 73, p. 79-88 10 p.

Research output: Contribution to journalArticle

Signal transduction
Autophagy
Proteasome Endopeptidase Complex
Ubiquitin
Ethanol
2 Citations
Endoplasmic Reticulum Stress
Lactation
Zinc
Oxidative Stress
Breast

Calcium store refilling and STIM activation in STIM- and Orai-deficient cell lines

Zheng, S., Zhou, L., Ma, G., Zhang, T., Liu, J., Li, J., Nguyen, N. T., Zhang, X., Li, W., Nwokonko, R., Zhou, Y., Zhao, F., Liu, J., Huang, Y., Gill, D. L. & Wang, Y., Jun 22 2018, (Accepted/In press) In : Pflugers Archiv European Journal of Physiology. p. 1-13 13 p.

Research output: Contribution to journalArticle

Oligomerization
Chemical activation
Cells
Calcium
Clustered Regularly Interspaced Short Palindromic Repeats

Characterization of a novel MYO3A missense mutation associated with a dominant form of late onset hearing loss

Dantas, V. G. L., Raval, M. H., Ballesteros, A., Cui, R., Gunther, L. K., Yamamoto, G. L., Alves, L. U., Bueno, A. S., Lezirovitz, K., Pirana, S., Mendes, B. C. A., Yengo, C. M., Kachar, B. & Mingroni-Netto, R. C., Dec 1 2018, In : Scientific Reports. 8, 1, 8706.

Research output: Contribution to journalArticle

Stereocilia
Missense Mutation
Hearing Loss
Actins
Myosins

CLIC1 and CLIC4 complement CA125 as a diagnostic biomarker panel for all subtypes of epithelial ovarian cancer

Singha, B., Harper, S. L., Goldman, A. R., Bitler, B. G., Aird, K. M., Borowsky, M. E., Cadungog, M. G., Liu, Q., Zhang, R., Jean, S., Drapkin, R. & Speicher, D. W., Dec 1 2018, In : Scientific Reports. 8, 1, 14725.

Research output: Contribution to journalArticle

Biomarkers
Neoplasms
Staining and Labeling
Serum
Organ Culture Techniques

Combination of hindlimb suspension and immobilization by casting exaggerates sarcopenia by stimulating autophagy but does not worsen osteopenia

Speacht, T. L., Krause, A. R., Steiner, J. L., Lang, C. & Donahue, H. J., May 1 2018, In : Bone. 110, p. 29-37 9 p.

Research output: Contribution to journalArticle

Sarcopenia
Hindlimb Suspension
Metabolic Bone Diseases
Autophagy
Muscles

Consumption of a high fat diet promotes protein O-GlcNAcylation in mouse retina via NR4A1-dependent GFAT2 expression

Dai, W., Dierschke, S. K., Toro, A. L. & Dennis, M. D., Dec 1 2018, In : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1864, 12, p. 3568-3576 9 p.

Research output: Contribution to journalArticle

Nuclear Receptor Subfamily 4, Group A, Member 1
High Fat Diet
Retina
Palmitates
Cell Culture Techniques
3 Citations

Crosslink between calcium and sodium signalling

Verkhratsky, A., Trebak, M., Perocchi, F., Khananshvili, D. & Sekler, I., Feb 1 2018, In : Experimental Physiology. 103, 2, p. 157-169 13 p.

Research output: Contribution to journalReview article

Calcium Signaling
Transient Receptor Potential Channels
Sodium
Ions
Synaptic Transmission
4 Citations

Cross-linking of Orai1 channels by STIM proteins

Zhou, Y., Nwokonko, R. M., Cai, X., Loktionova, N. A., Abdulqadir, R., Xin, P., Niemeyer, B. A., Wang, Y., Trebak, M. & Gill, D. L., Jan 1 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 15, p. E3398-E3407

Research output: Contribution to journalArticle

Endoplasmic Reticulum
Cell Membrane
Cluster Analysis
Fluorescence Recovery After Photobleaching
Protein Unfolding

Deletion of the Akt/mTORC1 repressor REDD1 prevents visual dysfunction in a rodent model of type 1 diabetes

Miller, W. P., Yang, C., Mihailescu, M. L., Moore, J. A., Dai, W., Barber, A. & Dennis, M., Jan 1 2018, In : Diabetes. 67, 1, p. 110-119 10 p.

Research output: Contribution to journalArticle

Type 1 Diabetes Mellitus
Rodentia
Cell Death
Retina
Contrast Sensitivity

Projects 1975 2022

Nitric oxide and microvessel permeability in vivo

He, P.

National Institutes of Health

12/12/1611/30/20

Project: Research projectResearch Project

Microvessels
Permeability
Reactive Oxygen Species
Nitric Oxide
Peroxynitrous Acid

Genes and miRNAs controlled by ORAI3 in cardiovascular remodeling

Trebak, M. & Lebeche, D.

National Institutes of Health

9/1/165/31/19

Project: Research projectExploratory/Developmental Grants

MicroRNAs
Muscle Cells
Blood Vessels
Ion Channels
Cardiac Myocytes

(PQ9) Novel therapeutic approaches to chemotherapy-induced muscle.

Waning, D.

National Institutes of Health

4/5/163/31/19

Project: Research projectExploratory/Developmental Grants

Ryanodine Receptor Calcium Release Channel
Muscle Weakness
Drug Therapy
Muscles
Oxidative Stress
Cardiac Myosins
Myosins
Cardiomyopathies
Mutation
Ventricular Myosins

Nucleotide Metabolism in Senescence and Platinum Resistance of Ovarian Cancer

Aird, K.

National Institutes of Health

4/3/1511/30/19

Project: Research projectCareer Transition Award, Research Transition Award

Platinum
Ovarian Neoplasms
Nucleotides
Neoplastic Stem Cells
Mentors

p90 Ribosomal S6 Kinase and Chronic Kidney Disease

Hu, K.

National Institutes of Health

8/10/145/31/19

Project: Research projectResearch Project

90-kDa Ribosomal Protein S6 Kinases
Chronic Renal Insufficiency
Low Density Lipoprotein Receptor-Related Protein-1
Kidney
Fibrosis

Research Training in Physiological Adaptations to Stress

Jefferson, L. ". & Korzick, D. H.

National Institutes of Health

7/1/146/30/19

Project: Research projectInstitutional National Research Service Award

Physiological Adaptation
Students
Education
Research
Precision Medicine

Calcium Signaling Roles of STIM1 and STIM2 in Smooth Muscle

Gill, D.

National Institutes of Health

6/5/142/28/19

Project: Research projectResearch Project

Calcium Signaling
Smooth Muscle Myocytes
Smooth Muscle
Growth
Phenotype

Receptor-regulated Ca2+ Entry Pathways in Smooth Muscle

Trebak, M.

National Institutes of Health

1/19/1012/31/20

Project: Research projectResearch Project

Vascular Smooth Muscle
Smooth Muscle Myocytes
Smooth Muscle
Vascular Diseases
Cell Movement

Control of Calcium Entry Signals in B Cells

Gill, D.

National Institutes of Health

1/1/045/31/20

Project: Research projectResearch Project

B-Lymphocytes
Calcium
Proteins
Molecular Probes
Protein Unfolding