Research Output 1989 2019

2019
1 Citation (Scopus)

Author Correction: The wide utility of rabbits as models of human diseases (Experimental & Molecular Medicine, (2018), 50, 5, (66), 10.1038/s12276-018-0094-1)

Esteves, P. J., Abrantes, J., Baldauf, H. M., BenMohamed, L., Chen, Y., Christensen, N., González-Gallego, J., Giacani, L., Hu, J., Kaplan, G., Keppler, O. T., Knight, K. L., Kong, X. P., Lanning, D. K., Le Pendu, J., de Matos, A. L., Liu, J., Liu, S., Lopes, A. M., Lu, S. & 17 others, Lukehart, S., Manabe, Y. C., Neves, F., McFadden, G., Pan, R., Peng, X., de Sousa-Pereira, P., Pinheiro, A., Rahman, M., Ruvoën-Clouet, N., Subbian, S., Tuñón, M. J., van der Loo, W., Vaine, M., Via, L. E., Wang, S. & Mage, R., Jul 1 2019, In : Experimental and Molecular Medicine. 51, 7, 71.

Research output: Contribution to journalComment/debate

Open Access
Molecular Medicine
Licensure
Medicine
Rabbits
Electrodes
Blood
Left ventricular assist devices
Pumps
Echocardiography
1 Citation (Scopus)

Chronic In Vivo Test of a Right Heart Replacement Blood Pump for Failed Fontan Circulation

Cysyk, J., Clark, J. B., Newswanger, R., Jhun, C-S., Izer, J., Finicle, H., Reibson, J., Doxtater, B., Weiss, W. & Rosenberg, G., Aug 1 2019, In : ASAIO journal (American Society for Artificial Internal Organs : 1992). 65, 6, p. 593-600 8 p.

Research output: Contribution to journalArticle

Superior Vena Cava
Venous Pressure
Inferior Vena Cava
Blood
Right Heart Bypass

Chronic Ovine Studies Demonstrate Low Thromboembolic Risk in the Penn State Infant Ventricular Assist Device

Lukic, B., Clark, J., Izer, J., Cooper, T. K., Finicle, H. A., Cysyk, J., Doxtater, B., Yeager, E., Reibson, J., Newswanger, R. K., Leibich, P., Bletcher, K. & Weiss, W., May 1 2019, In : ASAIO journal (American Society for Artificial Internal Organs : 1992). 65, 4, p. 371-379 9 p.

Research output: Contribution to journalArticle

Heart-Assist Devices
Sheep
Animals
Equipment and Supplies
Left ventricular assist devices
Point-of-Care Systems
Domestic Sheep
Dorset (sheep breed)
blood gases
crossbreds
hepatitis
biomarkers
anesthesia
kidneys
viruses

Endometrium and endometriosis tissue mitochondrial energy metabolism in a nonhuman primate model

Atkins, H. M., Bharadwaj, M. S., O'Brien Cox, A., Furdui, C. M., Appt, S. E. & Caudell, D. L., Aug 24 2019, In : Reproductive Biology and Endocrinology. 17, 1, 70.

Research output: Contribution to journalArticle

Open Access
Endometriosis
Endometrium
Energy Metabolism
Primates
Flavin-Adenine Dinucleotide

IgM Plasma Cells Reside in Healthy Skin and Accumulate with Chronic Inflammation

Wilson, R. P., McGettigan, S. E., Dang, V. D., Kumar, A., Cancro, M. P., Nikbakht, N., Stohl, W. & Debes, G. F., Jan 1 2019, (Accepted/In press) In : Journal of Investigative Dermatology. 139, 12, p. 2477-2487 11 p.

Research output: Contribution to journalArticle

Plasma Cells
Immunoglobulin M
Skin
Inflammation
Plasmas

Papillomavirus can be transmitted through the blood and produce infections in blood recipients: Evidence from two animal models

Cladel, N. M., Jiang, P., Li, J. J., Peng, X., Cooper, T. K., Majerciak, V., Balogh, K. K., Meyer, T. J., Brendle, S. A., Budgeon, L. R., Shearer, D. A., Munden, R., Cam, M., Vallur, R., Christensen, N., Zheng, Z. M. & Hu, J., Jan 1 2019, In : Emerging Microbes and Infections. 8, 1, p. 1108-1121 14 p.

Research output: Contribution to journalArticle

Open Access
Papillomavirus Infections
Animal Models
Infection
Neoplasms
Stomach

Short-Long Heart Rate Variation Increases Dispersion of Action Potential Duration in Long QT Type 2 Transgenic Rabbit Model

Kim, T. Y., Jeng, P., Hwang, J. M., Pfeiffer, Z., Patel, D., Cooper, L. L., Kossidas, K., Centracchio, J., Peng, X., Koren, G., Qu, Z. & Choi, B. R., Dec 1 2019, In : Scientific reports. 9, 1, 14849.

Research output: Contribution to journalArticle

Open Access
pamidronate
Long QT Syndrome
Action Potentials
Heart Rate
Rabbits
2 Citations (Scopus)
Cottontail rabbit papillomavirus
Papillomaviridae
rabbits
Sylvilagus floridanus
Rabbits
2018
1 Citation (Scopus)

Animal Models for Pediatric Mechanical Circulatory Support Research at Penn State Health

Izer, J., Wilson, R., Clark, J., Myers, J., Weiss, W. & Undar, A., Apr 1 2018, In : Artificial Organs. 42, 4, p. 347-353 7 p.

Research output: Contribution to journalEditorial

Artificial heart
Artificial Heart
Extracorporeal Membrane Oxygenation
Pediatrics
Heart-Assist Devices

Development of a Pain Scoring System for Use in Sheep Surgically Implanted with Ventricular Assist Devices

Izer, J., LaFleur, R. A., Weiss, W. & Wilson, R., Apr 11 2018, (Accepted/In press) In : Journal of Investigative Surgery. p. 1-10 10 p.

Research output: Contribution to journalArticle

Heart-Assist Devices
Sheep
Pain
Postoperative Pain
Biomedical Research
5 Citations (Scopus)

Impact of Different Perfusion Modalities on Coronary and Carotid Blood Flow Velocities in an Adult ECLS Swine Model

Wang, S., Patel, S., Izer, J., Clark, J., Kunselman, A., Wilson, R. & Undar, A., Sep 1 2018, In : Artificial organs. 42, 9, p. 918-921 4 p.

Research output: Contribution to journalArticle

Blood Flow Velocity
Flow velocity
Coronary Vessels
Blood
Swine

Labyrinthitis Ossificans in a Cynomolgus Macaque (Macaca fascicularis)

Balamayooran, G., Atkins, H., Whitlow, C. T., Aycock, S. T., Nader, M. A., Cline, J. M. & Caudell, D. L., Jun 1 2018, In : Comparative Medicine. 68, 3, p. 239-242 4 p.

Research output: Contribution to journalArticle

Labyrinthitis
Macaca fascicularis
Catheters
Audition
Macaca
2 Citations (Scopus)

Sex differences in antinociceptive response to Δ-9-tetrahydrocannabinol and CP 55,940 in the mouse formalin test

Lafleur, R. A., Wilson, R., Morgan, D. & Henderson-Redmond, A. N., Jan 1 2018, In : NeuroReport. 29, 6, p. 447-452 6 p.

Research output: Contribution to journalArticle

Dronabinol
Pain Measurement
Sex Characteristics
Cannabinoids
Cannabinoid Receptors

Systemic iron deficiency in a nonhuman primate model of endometriosis

Atkins, H., Appt, S. E., Taylor, R. N., Torres-Mendoza, Y., Lenk, E. E., Rosenthal, N. S. & Caudell, D. L., Aug 1 2018, In : Comparative Medicine. 68, 4, p. 298-307 10 p.

Research output: Contribution to journalArticle

Endometriosis
Primates
Iron
animal models
iron
11 Citations (Scopus)

The wide utility of rabbits as models of human diseases

Esteves, P. J., Abrantes, J., Baldauf, H. M., BenMohamed, L., Chen, Y., Christensen, N., González-Gallego, J., Giacani, L., Hu, J., Kaplan, G., Keppler, O. T., Knight, K. L., Kong, X. P., Lanning, D. K., Le Pendu, J., De Matos, A. L., Liu, J., Liu, S., Lopes, A. M., Lu, S. & 17 others, Lukehart, S., Manabe, Y. C., Neves, F., McFadden, G., Pan, R., Peng, X., de Sousa-Pereira, P., Pinheiro, A., Rahman, M., Ruvoën-Clouet, N., Subbian, S., Tuñón, M. J., van der Loo, W., Vaine, M., Via, L. E., Wang, S. & Mage, R., May 1 2018, In : Experimental and Molecular Medicine. 50, 5, 66.

Research output: Contribution to journalArticle

Rabbits
Virus Diseases
Vaccines
Acquired Immunodeficiency Syndrome
Rabies Vaccines
1 Citation (Scopus)

Transient Outward K+ Current (Ito) Underlies the Right Ventricular Initiation of Polymorphic Ventricular Tachycardia in a Transgenic Rabbit Model of Long-QT Syndrome Type 1

Choi, B. R., Li, W., Terentyev, D., Kabakov, A. Y., Zhong, M., Rees, C. M., Terentyeva, R., Kim, T. Y., Qu, Z., Peng, X., Karma, A. & Koren, G., Jun 1 2018, In : Circulation: Arrhythmia and Electrophysiology. 11, 6, e005414.

Research output: Contribution to journalArticle

Romano-Ward Syndrome
Ventricular Tachycardia
Heart Ventricles
Rabbits
Action Potentials
2017

Abdominal wall endometriosis in a rhesus macaque (Macaca mulatta)

Atkins, H., Caudell, D. L., Hutchison, A. R., LeGrande, A. C. & Kock, N. D., Jun 1 2017, In : Comparative Medicine. 67, 3, p. 277-280 4 p.

Research output: Contribution to journalArticle

Abdominal Wall
Endometriosis
Macaca mulatta
Tissue
Vimentin
Laboratory Animals
Internship and Residency
laboratory animals
medicine
animal
1 Citation (Scopus)

Cross-foster rederivation compared with antibiotic administration in the drinking water to eradicate bordetella pseudohinzii

Clark, S., Purcell, J. E., Bi, X. & Fortman, J. D., Jan 1 2017, In : Journal of the American Association for Laboratory Animal Science. 56, 1, p. 47-51 5 p.

Research output: Contribution to journalArticle

Bordetella
drinking water
cages
antibiotics
tetracycline
7 Citations (Scopus)

Mesenteric vascular dysregulation and intestinal inflammation accompanies experimental spinal cord injury

Besecker, E. M., Deiter, G. M., Pironi, N., Cooper, T. K. & Holmes, G. M., Jan 1 2017, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 312, 1, p. R146-R156

Research output: Contribution to journalArticle

Spinal Cord Injuries
Blood Vessels
Inflammation
Superior Mesenteric Artery
Hypotension
9 Citations (Scopus)

Podocyte-specific chemokine (C-C motif) receptor 2 overexpression mediates diabetic renal injury in mice

You, H., Gao, T., Raup-Konsavage, W. M., Cooper, T. K., Bronson, S. K., Reeves, W. B. & Awad, A. S., Mar 1 2017, In : Kidney International. 91, 3, p. 671-682 12 p.

Research output: Contribution to journalArticle

CCR Receptors
Podocytes
Kidney
Diabetic Nephropathies
Wounds and Injuries

Presumptive spontaneous lysosomal storage-like disease in a Crl:CD1(ICR) mouse

Hernon, K. M., Whitcomb, T., Davis, L. & Cooper, T., Feb 1 2017, In : Comparative Medicine. 67, 1, p. 28-33 6 p.

Research output: Contribution to journalArticle

Lysosomal Storage Diseases
Inbred ICR Mouse
Cholesterol Ester Storage Disease
Periodic Acid
Viscera
5 Citations (Scopus)

Soy protein concentrate mitigates markers of colonic inflammation and loss of gut barrier function in vitro and in vivo

Bitzer, Z. T., Wopperer, A. L., Chrisfield, B. J., Tao, L., Cooper, T., Vanamala, J. K. P., Elias, R., Hayes, J. E. & Lambert, J. D., Feb 1 2017, In : Journal of Nutritional Biochemistry. 40, p. 201-208 8 p.

Research output: Contribution to journalArticle

Soybean Proteins
Dextran Sulfate
Inflammation
Caspase 1
Splenomegaly
3 Citations (Scopus)

Spontaneous Lung Lesions in Aging Laboratory Rabbits (Oryctolagus cuniculus)

Cooper, T., Griffith, J. W., Chroneos, Z., Izer, J., Willing, L. B. & Peng, X., Jan 1 2017, In : Veterinary Pathology. 54, 1, p. 178-187 10 p.

Research output: Contribution to journalArticle

Oryctolagus cuniculus
lesions (animal)
rabbits
lungs
Rabbits
16 Citations (Scopus)

Successful chemoimmunotherapy against hepatocellular cancer in a novel murine model

Li, G., Liu, D., Cooper, T., Kimchi, E. T., Qi, X., Avella, D. M., Li, N., Yang, Q., Kester, M., Rountree, C. B., Kaifi, J. T., Cole, D. J., Rockey, D. C., Schell, T. & Staveley-O'Carroll, K. F., Jan 1 2017, In : Journal of Hepatology. 66, 1, p. 75-85 11 p.

Research output: Contribution to journalArticle

Liver Neoplasms
Neoplasms
Neoplasm Antigens
T-Lymphocytes
Programmed Cell Death 1 Receptor
5 Citations (Scopus)

Time course of peri-implant bone regeneration around loaded and unloaded implants in a rat model

Jariwala, S. H., Wee, H., Roush, E. P., Whitcomb, T. L., Murter, C., Kozlansky, G., Lakhtakia, A., Kunselman, A. R., Donahue, H. J., Armstrong, A. D. & Lewis, G. S., May 2017, In : Journal of Orthopaedic Research. 35, 5, p. 997-1006 10 p.

Research output: Contribution to journalArticle

Bone Regeneration
Extremities
Bone Resorption
Bone and Bones
Osteogenesis
3 Citations (Scopus)

Ultrasound-guided vessel catheterization in adult Yorkshire cross-bred pigs

Izer, J., Wilson, R., Hernon, K. & Undar, A., Jan 1 2017, In : Veterinary Anaesthesia and Analgesia. 44, 1, p. 133-137 5 p.

Research output: Contribution to journalArticle

Yorkshire (swine breed)
catheters
Catheterization
crossbreds
Swine
2016
15 Citations (Scopus)

Approaches to Investigating Complex Genetic Traits in a Large-Scale Inbred Mouse Aging Study

Sundberg, J. P., Berndt, A., Sundberg, B. A., Silva, K. A., Kennedy, V., Smith, R. S., Cooper, T. & Schofield, P. N., Mar 1 2016, In : Veterinary Pathology. 53, 2, p. 456-467 12 p.

Research output: Contribution to journalArticle

genetic traits
mice
Genome-Wide Association Study
Qa-SNARE Proteins
amyloidosis
10 Citations (Scopus)

A Role for MYC in Lithium-Stimulated Repair of the Colonic Epithelium After DSS-Induced Damage in Mice

Raup-Konsavage, W. M., Cooper, T. & Yochum, G., Feb 1 2016, In : Digestive Diseases and Sciences. 61, 2, p. 410-422 13 p.

Research output: Contribution to journalArticle

Dextran Sulfate
Lithium
Regeneration
Colitis
Epithelium
4 Citations (Scopus)

Bordetella pseudohinzii as a confounding organism in murine models of pulmonary disease

Clark, S., Purcell, J. E., Sammani, S., Steffen, E. K., Crim, M. J., Livingston, R. S., Besch-Williford, C. & Fortman, J. D., Oct 1 2016, In : Comparative Medicine. 66, 5, p. 361-366 6 p.

Research output: Contribution to journalArticle

Bordetella
Pulmonary diseases
respiratory tract diseases
Lung Diseases
animal models
5 Citations (Scopus)

Decidualization of Endometriosis in Macaques

Atkins, H. M., Lombardini, E. D., Caudell, D. L., Appt, S. E., Dubois, A. & Cline, J. M., Nov 1 2016, In : Veterinary Pathology. 53, 6, p. 1252-1258 7 p.

Research output: Contribution to journalArticle

Open Access
Macaca
Endometriosis
Decidua
pregnancy
Primates

Erratum to: Methionine-restricted diet inhibits growth of MCF10AT1-derived mammary tumors by increasing cell cycle inhibitors in athymic nude mice, [BMC Cancer., 16, (2016): 349] doi: 10.1186/s12885-016-2367-1

Hens, J. R., Sinha, I., Perodin, F., Cooper, T., Sinha, R., Plummer, J., Perrone, C. E. & Orentreich, D., Jul 14 2016, In : BMC Cancer. 16, 1, 474.

Research output: Contribution to journalArticle

Nude Mice
Methionine
Cell Cycle
Breast Neoplasms
Diet
24 Citations (Scopus)

FOXA1, GATA3 and PPARIγ Cooperate to drive luminal subtype in bladder cancer: A molecular analysis of established human cell lines

Warrick, J., Walter, V., Yamashita, H., Chung, E., Shuman, L., Amponsa, V. O., Zheng, Z., Chan, W., Whitcomb, T., Yue, F., Iyyanki, T., Imamura, Y., Kaag, M. G., Guo, W., Raman, J., Park, J. S. & Degraff, D., Dec 7 2016, In : Scientific reports. 6, 38531.

Research output: Contribution to journalArticle

Urinary Bladder Neoplasms
Cell Line
Basal Cell Neoplasms
Encyclopedias
Neoplasms
55 Citations (Scopus)

IFN-γ receptor and STAT1 signaling in B cells are central to spontaneous germinal center formation and autoimmunity

Domeier, P. P., Chodisetti, S. B., Soni, C., Schell, S. L., Elias, M. J., Wong, E. B., Cooper, T., Kitamura, D. & Rahman, Z., Jan 1 2016, In : Journal of Experimental Medicine. 213, 5, p. 715-732 18 p.

Research output: Contribution to journalArticle

Germinal Center
Autoimmunity
B-Lymphocytes
Antigens
Nuclear Antigens
9 Citations (Scopus)

Methionine-restricted diet inhibits growth of MCF10AT1-derived mammary tumors by increasing cell cycle inhibitors in athymic nude mice

Hens, J. R., Sinha, I., Perodin, F., Cooper, T., Sinha, R., Plummer, J., Perrone, C. E. & Orentreich, D., Jun 3 2016, In : BMC Cancer. 16, 1, 349.

Research output: Contribution to journalArticle

Nude Mice
Methionine
Cell Cycle
Breast Neoplasms
Diet
10 Citations (Scopus)

Mouse papillomavirus MmuPV1 infects oral mucosa and preferentially targets the base of the tongue

Cladel, N. M., Budgeon, L. R., Balogh, K. K., Cooper, T., Hu, J. & Christensen, N., Jan 15 2016, In : Virology. 488, p. 73-80 8 p.

Research output: Contribution to journalArticle

Mouth Mucosa
Tongue
Nude Mice
Papillomavirus Infections
Infection
2 Citations (Scopus)

Practicing handoffs early: Applying a clinical framework in the anatomy laboratory

Lazarus, M. D., Dos Santos, J., Haidet, P. & Whitcomb, T., Oct 1 2016, In : Anatomical Sciences Education. 9, 5, p. 476-487 12 p.

Research output: Contribution to journalArticle

Anatomy
Students
Learning
Clinical Competence
Teaching

Response to Protocol Review Scenario: The spirit of the law

Wilson, R., Lafleur, R. A. & Munden, R. L., Dec 19 2016, In : Lab Animal. 46, 1, 1 p.

Research output: Contribution to journalComment/debate

15 Citations (Scopus)

Sorafenib and quinacrine target anti-apoptotic protein MCL1: A poor prognostic marker in Anaplastic Thyroid Cancer (ATC)

Abdulghani, J., Gokare, P., Gallant, J. N., Dicker, D., Whitcomb, T., Cooper, T., Liao, J. J., Derr, J., Liu, J., Goldenberg, D., Finnberg, N. K. & El-Deiry, W. S., Dec 15 2016, In : Clinical Cancer Research. 22, 24, p. 6192-6203 12 p.

Research output: Contribution to journalArticle

Quinacrine
Apoptosis Regulatory Proteins
Thyroid Neoplasms
Anaplastic Thyroid Carcinoma
sorafenib
9 Citations (Scopus)

The Clinical Importance of Pulsatile Flow in Extracorporeal Life Support: The Penn State Health Approach

Undar, A., Wang, S., Izer, J., Clark, J., Kunselman, A., Patel, S., Shank, K., Profeta, E., Wilson, R. & Ostadal, P., Dec 1 2016, In : Artificial Organs. 40, 12, p. 1101-1104 4 p.

Research output: Contribution to journalArticle

Pulsatile Flow
Pulsatile flow
Extracorporeal Membrane Oxygenation
Left Ventricular Function
Respiratory Insufficiency
5 Citations (Scopus)

Valvular and Mural Endocardiosis in Aging Zebrafish (Danio rerio)

Cooper, T. & Spitsbergen, J. M., Mar 1 2016, In : Veterinary Pathology. 53, 2, p. 504-509 6 p.

Research output: Contribution to journalArticle

Zebrafish
Danio rerio
Fishes
fish
lesions (animal)
2015
16 Citations (Scopus)

A novel pre-clinical murine model to study the life cycle and progression of cervical and anal papillomavirus infections

Cladel, N. M., Budgeon, L. R., Balogh, K. K., Cooper, T., Hu, J. & Christensen, N., Mar 24 2015, In : PloS one. 10, 3, e0120128.

Research output: Contribution to journalArticle

Papillomavirus Infections
Papillomaviridae
Life Cycle Stages
Life cycle
life cycle (organisms)
12 Citations (Scopus)

Arginase inhibition: A new treatment for preventing progression of established diabetic nephropathy

You, H., Gao, T., Cooper, T. K., Morris, S. M. & Awad, A. S., Sep 4 2015, In : American Journal of Physiology - Renal Physiology. 309, 5, p. F447-F455

Research output: Contribution to journalArticle

Arginase
Diabetic Nephropathies
Captopril
Kidney
Albuminuria
4 Citations (Scopus)

Chapter 24 - Preanesthesia, Anesthesia, Analgesia, and Euthanasia

Flecknell, P., Lofgren, J. L. S., Dyson, M. C., Marini, R. R., Michael Swindle, M. & Wilson, R., Jan 1 2015, Laboratory Animal Medicine: Third Edition. Elsevier Inc., p. 1135-1200 66 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Anesthesia and Analgesia
Euthanasia
Laboratory Animals
analgesics
euthanasia
17 Citations (Scopus)

Complex excitation dynamics underlie polymorphic ventricular tachycardia in a transgenic rabbit model of long QT syndrome type 1

Kim, T. Y., Kunitomo, Y., Pfeiffer, Z., Patel, D., Hwang, J., Harrison, K., Patel, B., Jeng, P., Ziv, O., Lu, Y., Peng, X., Qu, Z., Koren, G. & Choi, B. R., Jan 1 2015, In : Heart Rhythm. 12, 1, p. 220-228 9 p.

Research output: Contribution to journalArticle

Romano-Ward Syndrome
Ventricular Tachycardia
Rabbits
Action Potentials
Heart Ventricles

Correction: Spatially discordant alternans and arrhythmias in tachypacing-induced cardiac myopathy in transgenic LQT1 rabbits: The importance of IKsand Ca2+ cycling

Lau, E., Kossidas, K., Kim, T. Y., Kunitomo, Y., Ziv, O., Song, Z., Taylor, C., Schofield, L., Yammine, J., Liu, G., Peng, X., Qu, Z., Koren, G. & Choi, B. R., Jul 1 2015, In : PloS one. 10, 7, e0132198.

Research output: Contribution to journalComment/debate

7 Citations (Scopus)

Delayed treatment with a small pigment epithelium derived factor (PEDF) peptide prevents the progression of diabetic renal injury

Awad, A. S., You, H., Gao, T., Gvritishvili, A., Cooper, T. K. & Tombran-Tink, J., Jul 24 2015, In : PloS one. 10, 7, e0133777.

Research output: Contribution to journalArticle

diabetic nephropathy
Diabetic Nephropathies
epithelium
pigments
kidneys