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2020

CD8 T cells and STAT1 signaling are essential codeterminants in protection from polyomavirus encephalopathy

Mockus, T. E., Netherby-Winslow, C. S., Atkins, H. M., Lauver, M. D., Jin, G., Ren, H. M. & Lukacher, A. E., Mar 1 2020, In : Journal of virology. 94, 8, e02038-19.

Research output: Contribution to journalArticle

Late INa Blocker GS967 Supresses Polymorphic Ventricular Tachycardia in a Transgenic Rabbit Model of Long QT Type 2

Hwang, J., Kim, T. Y., Terentyev, D., Zhong, M., Kabakov, A. Y., Bronk, P., Arunachalam, K., Belardinelli, L., Rajamani, S., Kunitomo, Y., Pfeiffer, Z., Lu, Y., Peng, X., Odening, K. E., Qu, Z., Karma, A., Koren, G. & Choi, B. R., Aug 1 2020, In : Circulation. Arrhythmia and electrophysiology. 13, 8, p. e006875

Research output: Contribution to journalArticle

Serine phosphorylation of the STAT1 transactivation domain promotes autoreactive B cell and systemic autoimmunity development

Chodisetti, S. B., Fike, A. J., Domeier, P. P., Schell, S. L., Mockus, T. E., Choi, N. M., Corradetti, C., Hou, B., Atkins, H. M., Caricchio, R., Decker, T., Lukacher, A., Olsen, N. & Rahman, Z. S. M., May 15 2020, In : Journal of Immunology. 204, 10, p. 2641-2650 10 p.

Research output: Contribution to journalArticle

1 Scopus citations
2019
3 Scopus citations

Chronic In Vivo Test of a Right Heart Replacement Blood Pump for Failed Fontan Circulation

Cysyk, J., Clark, J. B., Newswanger, R., Jhun, C. S., Izer, J., Finicle, H., Reibson, J., Doxtater, B., Weiss, W. & Rosenberg, G., Aug 1 2019, In : ASAIO Journal. 65, 6, p. 593-600 8 p.

Research output: Contribution to journalArticle

3 Scopus citations

Chronic ovine studies demonstrate low thromboembolic risk in the Penn State infant ventricular assist device

Lukic, B., Brian Clark, J., Izer, J. M., Cooper, T. K., Finicle, H. A., Cysyk, J., Doxtater, B., Yeager, E., Reibson, J., Newswanger, R. K., Leibich, P., Bletcher, K. & Weiss, W. J., 2019, In : ASAIO Journal. 65, 4, p. 371-379 9 p.

Research output: Contribution to journalArticle

2 Scopus citations

Development of a Pain Scoring System for Use in Sheep Surgically Implanted with Ventricular Assist Devices

Izer, J. M., LaFleur, R. A., Weiss, W. J. & Wilson, R. P., Nov 17 2019, In : Journal of Investigative Surgery. 32, 8, p. 706-715 10 p.

Research output: Contribution to journalArticle

Endometrium and endometriosis tissue mitochondrial energy metabolism in a nonhuman primate model

Atkins, H. M., Bharadwaj, M. S., O'Brien Cox, A., Furdui, C. M., Appt, S. E. & Caudell, D. L., Aug 24 2019, In : Reproductive Biology and Endocrinology. 17, 1, 70.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

IgM Plasma Cells Reside in Healthy Skin and Accumulate with Chronic Inflammation

Wilson, R. P., McGettigan, S. E., Dang, V. D., Kumar, A., Cancro, M. P., Nikbakht, N., Stohl, W. & Debes, G. F., Dec 2019, In : Journal of Investigative Dermatology. 139, 12, p. 2477-2487 11 p.

Research output: Contribution to journalArticle

6 Scopus citations

Papillomavirus can be transmitted through the blood and produce infections in blood recipients: Evidence from two animal models

Cladel, N. M., Jiang, P., Li, J. J., Peng, X., Cooper, T. K., Majerciak, V., Balogh, K. K., Meyer, T. J., Brendle, S. A., Budgeon, L. R., Shearer, D. A., Munden, R., Cam, M., Vallur, R., Christensen, N. D., Zheng, Z. M. & Hu, J., Jan 1 2019, In : Emerging Microbes and Infections. 8, 1, p. 1108-1121 14 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Short-Long Heart Rate Variation Increases Dispersion of Action Potential Duration in Long QT Type 2 Transgenic Rabbit Model

Kim, T. Y., Jeng, P., Hwang, J. M., Pfeiffer, Z., Patel, D., Cooper, L. L., Kossidas, K., Centracchio, J., Peng, X., Koren, G., Qu, Z. & Choi, B. R., Dec 1 2019, In : Scientific reports. 9, 1, 14849.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
2018

Combined sublethal irradiation and agonist anti-CD40 enhance donor T cell accumulation and control of autochthonous murine pancreatic tumors

Ward-Kavanagh, L. K., Kokolus, K. M., Cooper, T. K., Lukacher, A. E. & Schell, T. D., Apr 1 2018, In : Cancer Immunology, Immunotherapy. 67, 4, p. 639-652 14 p.

Research output: Contribution to journalArticle

4 Scopus citations

Effects of Black Raspberry on Dibenzo[a,l]Pyrene Diol Epoxide Induced DNAAdducts, Mutagenesis, and Tumorigenesis in the Mouse Oral Cavity

Chen, K. M., Guttenplan, J. B., Sun, Y. W., Cooper, T., Shalaby, N. A. E., Kosinska, W., Benitez, G., Aliaga, C., Zhu, J., Liao, J., Gowda, K., Amin, S., Stoner, G. & El-Bayoumy, K., Mar 2018, In : Cancer Prevention Research. 11, 3, p. 157-164 8 p.

Research output: Contribution to journalArticle

6 Scopus citations

Impact of Different Perfusion Modalities on Coronary and Carotid Blood Flow Velocities in an Adult ECLS Swine Model

Wang, S., Patel, S., Izer, J., Clark, J., Kunselman, A., Wilson, R. & Undar, A., Sep 2018, In : Artificial organs. 42, 9, p. 918-921 4 p.

Research output: Contribution to journalArticle

5 Scopus citations

Labyrinthitis Ossificans in a Cynomolgus Macaque (Macaca fascicularis)

Balamayooran, G., Atkins, H. M., Whitlow, C. T., Aycock, S. T., Nader, M. A., Cline, J. M. & Caudell, D. L., Jun 2018, In : Comparative Medicine. 68, 3, p. 239-242 4 p.

Research output: Contribution to journalArticle

Sex differences in antinociceptive response to Δ-9-tetrahydrocannabinol and CP 55,940 in the mouse formalin test

Lafleur, R. A., Wilson, R. P., Morgan, D. J. & Henderson-Redmond, A. N., 2018, In : Neuroreport. 29, 6, p. 447-452 6 p.

Research output: Contribution to journalArticle

4 Scopus citations

Systemic iron deficiency in a nonhuman primate model of endometriosis

Atkins, H. M., Appt, S. E., Taylor, R. N., Torres-Mendoza, Y., Lenk, E. E., Rosenthal, N. S. & Caudell, D. L., Aug 2018, In : Comparative Medicine. 68, 4, p. 298-307 10 p.

Research output: Contribution to journalArticle

The wide utility of rabbits as models of human diseases

Esteves, P. J., Abrantes, J., Baldauf, H. M., BenMohamed, L., Chen, Y., Christensen, N., González-Gallego, J., Giacani, L., Hu, J., Kaplan, G., Keppler, O. T., Knight, K. L., Kong, X. P., Lanning, D. K., Le Pendu, J., De Matos, A. L., Liu, J., Liu, S., Lopes, A. M., Lu, S. & 17 others, Lukehart, S., Manabe, Y. C., Neves, F., McFadden, G., Pan, R., Peng, X., de Sousa-Pereira, P., Pinheiro, A., Rahman, M., Ruvoën-Clouet, N., Subbian, S., Tuñón, M. J., van der Loo, W., Vaine, M., Via, L. E., Wang, S. & Mage, R., May 2018, In : Experimental and Molecular Medicine. 50, 5, 66.

Research output: Contribution to journalArticle

24 Scopus citations

Transient Outward K+ Current (Ito) Underlies the Right Ventricular Initiation of Polymorphic Ventricular Tachycardia in a Transgenic Rabbit Model of Long-QT Syndrome Type 1

Choi, B. R., Li, W., Terentyev, D., Kabakov, A. Y., Zhong, M., Rees, C. M., Terentyeva, R., Kim, T. Y., Qu, Z., Peng, X., Karma, A. & Koren, G., Jun 1 2018, In : Circulation: Arrhythmia and Electrophysiology. 11, 6, e005414.

Research output: Contribution to journalArticle

4 Scopus citations
2017

Abdominal wall endometriosis in a rhesus macaque (Macaca mulatta)

Atkins, H. M., Caudell, D. L., Hutchison, A. R., LeGrande, A. C. & Kock, N. D., Jun 2017, In : Comparative Medicine. 67, 3, p. 277-280 4 p.

Research output: Contribution to journalArticle

Cross-foster rederivation compared with antibiotic administration in the drinking water to eradicate bordetella pseudohinzii

Clark, S., Purcell, J. E., Bi, X. & Fortman, J. D., Jan 1 2017, In : Journal of the American Association for Laboratory Animal Science. 56, 1, p. 47-51 5 p.

Research output: Contribution to journalArticle

1 Scopus citations

Mesenteric vascular dysregulation and intestinal inflammation accompanies experimental spinal cord injury

Besecker, E. M., Deiter, G. M., Pironi, N., Cooper, T. K. & Holmes, G. M., 2017, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 312, 1, p. R146-R156

Research output: Contribution to journalArticle

10 Scopus citations

Mouse papillomavirus infections spread to cutaneous sites with progression to malignancy

Cladel, N. M., Budgeon, L. R., Cooper, T. K., Balogh, K. K., Christensen, N. D., Myers, R., Majerciak, V., Gotte, D., Zheng, Z. M. & Hu, J., Oct 2017, In : Journal of General Virology. 98, 10, p. 2520-2529 10 p., 000926.

Research output: Contribution to journalArticle

8 Scopus citations

Podocyte-specific chemokine (C-C motif) receptor 2 overexpression mediates diabetic renal injury in mice

You, H., Gao, T., Raup-Konsavage, W. M., Cooper, T. K., Bronson, S. K., Reeves, W. B. & Awad, A. S., Mar 1 2017, In : Kidney International. 91, 3, p. 671-682 12 p.

Research output: Contribution to journalArticle

13 Scopus citations

Presumptive spontaneous lysosomal storage-like disease in a Crl:CD1(ICR) mouse

Hernon, K. M., Whitcomb, T. L., Davis, L. & Cooper, T. K., Feb 2017, In : Comparative Medicine. 67, 1, p. 28-33 6 p.

Research output: Contribution to journalArticle

Prostate Cancer Xenograft Inhibitory Activity and Pharmacokinetics of Decursinol, a Metabolite of Angelica gigas Pyranocoumarins, in Mouse Models

Wu, W., Tang, S. N., Zhang, Y., Puppala, M., Cooper, T. K., Xing, C., Jiang, C. & Lü, J., 2017, In : American Journal of Chinese Medicine. 45, 8, p. 1773-1792 20 p.

Research output: Contribution to journalArticle

2 Scopus citations

Soy protein concentrate mitigates markers of colonic inflammation and loss of gut barrier function in vitro and in vivo

Bitzer, Z. T., Wopperer, A. L., Chrisfield, B. J., Tao, L., Cooper, T. K., Vanamala, J., Elias, R. J., Hayes, J. E. & Lambert, J. D., Feb 1 2017, In : Journal of Nutritional Biochemistry. 40, p. 201-208 8 p.

Research output: Contribution to journalArticle

8 Scopus citations

Spontaneous Lung Lesions in Aging Laboratory Rabbits (Oryctolagus cuniculus)

Cooper, T. K., Griffith, J. W., Chroneos, Z. C., Izer, J. M., Willing, L. B. & Peng, X., Jan 1 2017, In : Veterinary Pathology. 54, 1, p. 178-187 10 p.

Research output: Contribution to journalArticle

4 Scopus citations

Successful chemoimmunotherapy against hepatocellular cancer in a novel murine model

Li, G., Liu, D., Cooper, T. K., Kimchi, E. T., Qi, X., Avella, D. M., Li, N., Yang, Q. X., Kester, M., Rountree, C. B., Kaifi, J. T., Cole, D. J., Rockey, D. C., Schell, T. D. & Staveley-O'Carroll, K. F., Jan 1 2017, In : Journal of Hepatology. 66, 1, p. 75-85 11 p.

Research output: Contribution to journalArticle

24 Scopus citations

Time course of peri-implant bone regeneration around loaded and unloaded implants in a rat model

Jariwala, S. H., Wee, H., Roush, E. P., Whitcomb, T. L., Murter, C., Kozlansky, G., Lakhtakia, A., Kunselman, A. R., Donahue, H. J., Armstrong, A. D. & Lewis, G. S., May 2017, In : Journal of Orthopaedic Research. 35, 5, p. 997-1006 10 p.

Research output: Contribution to journalArticle

5 Scopus citations

Ultrasound-guided vessel catheterization in adult Yorkshire cross-bred pigs

Izer, J., Wilson, R., Hernon, K. & Ündar, A., Jan 2017, In : Veterinary Anaesthesia and Analgesia. 44, 1, p. 133-137 5 p.

Research output: Contribution to journalArticle

3 Scopus citations
2016

Approaches to Investigating Complex Genetic Traits in a Large-Scale Inbred Mouse Aging Study

Sundberg, J. P., Berndt, A., Sundberg, B. A., Silva, K. A., Kennedy, V., Smith, R. S., Cooper, T. K. & Schofield, P. N., Mar 1 2016, In : Veterinary Pathology. 53, 2, p. 456-467 12 p.

Research output: Contribution to journalArticle

15 Scopus citations

A Role for MYC in Lithium-Stimulated Repair of the Colonic Epithelium After DSS-Induced Damage in Mice

Raup-Konsavage, W. M., Cooper, T. K. & Yochum, G. S., Feb 1 2016, In : Digestive Diseases and Sciences. 61, 2, p. 410-422 13 p.

Research output: Contribution to journalArticle

13 Scopus citations

Bordetella pseudohinzii as a confounding organism in murine models of pulmonary disease

Clark, S. E., Purcell, J. E., Sammani, S., Steffen, E. K., Crim, M. J., Livingston, R. S., Besch-Williford, C. & Fortman, J. D., Oct 2016, In : Comparative Medicine. 66, 5, p. 361-366 6 p.

Research output: Contribution to journalArticle

6 Scopus citations

Decidualization of Endometriosis in Macaques

Atkins, H. M., Lombardini, E. D., Caudell, D. L., Appt, S. E., Dubois, A. & Cline, J. M., Nov 1 2016, In : Veterinary Pathology. 53, 6, p. 1252-1258 7 p.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

Erratum to: Methionine-restricted diet inhibits growth of MCF10AT1-derived mammary tumors by increasing cell cycle inhibitors in athymic nude mice, [BMC Cancer., 16, (2016): 349] doi: 10.1186/s12885-016-2367-1

Hens, J. R., Sinha, I., Perodin, F., Cooper, T., Sinha, R., Plummer, J., Perrone, C. E. & Orentreich, D., Jul 14 2016, In : BMC Cancer. 16, 1, 474.

Research output: Contribution to journalArticle

1 Scopus citations

FOXA1, GATA3 and PPARIγ Cooperate to drive luminal subtype in bladder cancer: A molecular analysis of established human cell lines

Warrick, J. I., Walter, V., Yamashita, H., Chung, E., Shuman, L., Amponsa, V. O., Zheng, Z., Chan, W., Whitcomb, T. L., Yue, F., Iyyanki, T., Kawasawa, Y. I., Kaag, M., Guo, W., Raman, J. D., Park, J. S. & Degraff, D. J., Dec 7 2016, In : Scientific reports. 6, 38531.

Research output: Contribution to journalArticle

38 Scopus citations

IFN-γ receptor and STAT1 signaling in B cells are central to spontaneous germinal center formation and autoimmunity

Domeier, P. P., Chodisetti, S. B., Soni, C., Schell, S. L., Elias, M. J., Wong, E. B., Cooper, T. K., Kitamura, D. & Rahman, Z. S. M., May 2 2016, In : Journal of Experimental Medicine. 213, 5, p. 715-732 18 p.

Research output: Contribution to journalArticle

78 Scopus citations

Methionine-restricted diet inhibits growth of MCF10AT1-derived mammary tumors by increasing cell cycle inhibitors in athymic nude mice

Hens, J. R., Sinha, I., Perodin, F., Cooper, T., Sinha, R., Plummer, J., Perrone, C. E. & Orentreich, D., Jun 3 2016, In : BMC Cancer. 16, 1, 349.

Research output: Contribution to journalArticle

17 Scopus citations

Mouse papillomavirus MmuPV1 infects oral mucosa and preferentially targets the base of the tongue

Cladel, N. M., Budgeon, L. R., Balogh, K. K., Cooper, T., Hu, J. & Christensen, N., Jan 15 2016, In : Virology. 488, p. 73-80 8 p.

Research output: Contribution to journalArticle

14 Scopus citations

Practicing handoffs early: Applying a clinical framework in the anatomy laboratory

Lazarus, M. D., Dos Santos, J. A., Haidet, P. M. & Whitcomb, T. L., Oct 1 2016, In : Anatomical sciences education. 9, 5, p. 476-487 12 p.

Research output: Contribution to journalArticle

2 Scopus citations

Sorafenib and quinacrine target anti-apoptotic protein MCL1: A poor prognostic marker in Anaplastic Thyroid Cancer (ATC)

Abdulghani, J., Gokare, P., Gallant, J. N., Dicker, D., Whitcomb, T., Cooper, T., Liao, J., Derr, J., Liu, J., Goldenberg, D., Finnberg, N. K. & El-Deiry, W. S., Dec 15 2016, In : Clinical Cancer Research. 22, 24, p. 6192-6203 12 p.

Research output: Contribution to journalArticle

20 Scopus citations

The Clinical Importance of Pulsatile Flow in Extracorporeal Life Support: The Penn State Health Approach

Undar, A., Wang, S., Izer, J., Clark, J., Kunselman, A., Patel, S., Shank, K., Profeta, E., Wilson, R. & Ostadal, P., Dec 1 2016, In : Artificial organs. 40, 12, p. 1101-1104 4 p.

Research output: Contribution to journalArticle

9 Scopus citations

Valvular and Mural Endocardiosis in Aging Zebrafish (Danio rerio)

Cooper, T. K. & Spitsbergen, J. M., Mar 1 2016, In : Veterinary Pathology. 53, 2, p. 504-509 6 p.

Research output: Contribution to journalArticle

5 Scopus citations
2015

A novel pre-clinical murine model to study the life cycle and progression of cervical and anal papillomavirus infections

Cladel, N. M., Budgeon, L. R., Balogh, K. K., Cooper, T. K., Hu, J. & Christensen, N. D., Mar 24 2015, In : PloS one. 10, 3, e0120128.

Research output: Contribution to journalArticle

21 Scopus citations

Arginase inhibition: A new treatment for preventing progression of established diabetic nephropathy

You, H., Gao, T., Cooper, T. K., Morris, S. M. & Awad, A. S., Sep 4 2015, In : American Journal of Physiology - Renal Physiology. 309, 5, p. F447-F455

Research output: Contribution to journalArticle

14 Scopus citations