Department of Microbiology and Immunology

  • United States

Research Output

2020

A Physiological Basis for Nonheritable Antibiotic Resistance

Pontes, M. H. & Groisman, E. A., Jun 16 2020, In : mBio. 11, 3

Research output: Contribution to journalReview article

Open Access

Context-dependent activation of SIRT3 is necessary for anchorage-independent survival and metastasis of ovarian cancer cells

Kim, Y. S., Gupta Vallur, P., Jones, V. M., Worley, B. L., Shimko, S., Shin, D. H., Crawford, L. T. C., Chen, C. W., Aird, K. M., Abraham, T., Shepherd, T. G., Warrick, J. I., Lee, N. Y., Phaeton, R., Mythreye, K. & Hempel, N., Feb 20 2020, In : Oncogene. 39, 8, p. 1619-1633 15 p.

Research output: Contribution to journalArticle

Gut-resident CX3CR1hi macrophages induce tertiary lymphoid structures and IgA response in situ

Koscsó, B., Kurapati, S., Rodrigues, R. R., Nedjic, J., Gowda, K., Shin, C., Soni, C., Ashraf, A. Z., Purushothaman, I., Palisoc, M., Xu, S., Sun, H., Chodisetti, S. B., Lin, E., Mack, M., Imamura, Y., He, P., Rahman, Z. S. M., Aifantis, I., Shulzhenko, N. & 2 others, Morgun, A. & Bogunovic, M., Jan 1 2020, In : Science Immunology. 5, 46, eaax0062.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Involvement of host atr-chk1 pathway in hepatitis b virus covalently closed circular dna formation

Luo, J., Luckenbaugh, L., Hu, H., Yan, Z., Gao, L. & Hu, J., Jan 1 2020, In : mBio. 11, 1, e03423-19.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Limited intrahost diversity and background evolution accompany 40 years of canine parvovirus host adaptation and spread

Voorhees, I. E. H., Lee, H., Allison, A. B., Lopez-Astacio, R., Goodman, L. B., Oyesola, O. O., Omobowale, O., Fagbohun, O., Dubovi, E. J., Hafenstein, S. L., Holmes, E. C. & Parrish, C. R., Jan 1 2020, In : Journal of virology. 94, 1, e01162-19.

Research output: Contribution to journalArticle

3 Scopus citations
Open Access
Open Access

Mutational profile of endometrial hyperplasia and risk of progression to endometrioid adenocarcinoma

Russo, M., Newell, J. M., Budurlean, L., Houser, K. R., Sheldon, K., Kesterson, J., Phaeton, R., Hossler, C., Rosenberg, J., DeGraff, D., Shuman, L., Broach, J. R. & Warrick, J. I., Jun 15 2020, In : Cancer. 126, 12, p. 2775-2783 9 p.

Research output: Contribution to journalArticle

RNA-binding domains of heterologous viral proteins substituted for basic residues in the RSV gag NC domain restore specific packaging of genomic RNA

Rice, B. L., Lochmann, T. L. & Parent, L. J., Jan 1 2020, In : Viruses. 12, 4, 370.

Research output: Contribution to journalArticle

Open Access

Role of hepatitis B virus capsid phosphorylation in nucleocapsid disassembly and covalently closed circular DNA formation

Luo, J., Xi, J., Gao, L. & Hu, J., Jan 1 2020, In : PLoS pathogens. 16, 3, e1008459.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Rous sarcoma virus genomic RNA dimerization capability in vitro is not a prerequisite for viral infectivity

Liu, S., Maldonado, R. K., Rye-McCurdy, T., Binkley, C., Bah, A., Chen, E. C., Rice, B. L., Parent, L. J. & Musier-Forsyth, K., May 2020, In : Viruses. 12, 5, 568.

Research output: Contribution to journalArticle

Open Access

Scaffold Simplification Strategy Leads to a Novel Generation of Dual Human Immunodeficiency Virus and Enterovirus-A71 Entry Inhibitors

Martínez-Gualda, B., Sun, L., Martí-Marí, O., Noppen, S., Abdelnabi, R., Bator, C. M., Quesada, E., Delang, L., Mirabelli, C., Lee, H., Schols, D., Neyts, J., Hafenstein, S., Camarasa, M. J., Gago, F. & San-Félix, A., Jan 9 2020, In : Journal of Medicinal Chemistry. 63, 1, p. 349-368 20 p.

Research output: Contribution to journalArticle

1 Scopus citations

Serine phosphorylation of the STAT1 transactivation domain promotes autoreactive B cell and systemic autoimmunity development

Chodisetti, S. B., Fike, A. J., Domeier, P. P., Schell, S. L., Mockus, T. E., Choi, N. M., Corradetti, C., Hou, B., Atkins, H. M., Caricchio, R., Decker, T., Lukacher, A. E., Olsen, N. & Rahman, Z. S. M., May 15 2020, In : Journal of Immunology. 204, 10, p. 2641-2650 10 p.

Research output: Contribution to journalArticle

Serum HBV RNA composition dynamics as a marker for intrahepatic HBV cccDNA turnover

Hong, X. & Hu, J., Jan 1 2020, (Accepted/In press) In : Journal of Medical Virology.

Research output: Contribution to journalComment/debate

Open Access

Type II but not type I IFN signaling is indispensable for TLR7-promoted development of autoreactive B cells and systemic autoimmunity

Chodisetti, S. B., Fike, A. J., Domeier, P. P., Singh, H., Choi, N. M., Corradetti, C., Kawasawa, Y. I., Cooper, T. K., Caricchio, R. & Rahman, Z. S. M., Feb 15 2020, In : Journal of Immunology. 204, 4, p. 796-809 14 p.

Research output: Contribution to journalArticle

1 Scopus citations

Vaccinia Virus Glycoproteins A33, A34, and B5 Form a Complex for Efficient Endoplasmic Reticulum to trans-Golgi Network Transport

Monticelli, S. R., Earley, A. K., Stone, R., Norbury, C. C. & Ward, B. M., Apr 1 2020, In : Journal of virology. 94, 7, e0215519.

Research output: Contribution to journalArticle

Open Access

Visualizing association of the retroviral gag protein with unspliced viral RNA in the nucleus

Maldonado, R. J. K., Rice, B., Chen, E. C., Tuffy, K. M., Chiari, E. F., Fahrbach, K. M., Hope, T. J. & Parent, L. J., Mar 1 2020, In : mBio. 11, 2, e00524-20.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
2019

17β-Estradiol affects lung function and inflammation following ozone exposure in a sex-specific manner

Fuentes, N., Nicoleau, M., Cabello, N., Montes, D., Zomorodi, N., Chroneos, Z. C. & Silveyra, P., Jan 1 2019, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 317, 5, p. L702-L716

Research output: Contribution to journalArticle

2 Scopus citations

Abstracts of Presentations at the Association of Clinical Scientists 139th Meeting Hershey, PA, May 15-18, 2019

Donaldson, K., Buchanich, J. M., Grigson, P. S., Deneke, E., Vrana, K. E., Sacks, D. B., Kuehn, G. J., Cardamone, D., Pesce, A., Smiley, S., Nickley, J., Krock, K., Thomas, R., Wilkerson, M. L., Farag, H. A., Challa, S. R., Tice, A. M., Wolk, D. M., Prichard, J., Grant, M. L. & 102 others, Regmi, S., Kerbacher, B., Quinton, L. E., Tice, A. M., Olson, J., Haynes, A., Yu, E., McCully, K. S., Assi, J., Wong, M., Zarrin-Khameh, N., Nifong, T. P., Hawker, C. D., Carlton, G. T., Rivera, J. M., Foulis, P. R., Zuraw, A., Morlote, D., Peker, D., Reddy, V., Harada, S., Crutchfield, C., Zander, D., Barbhuiya, M. A., Pederson, E. C., Straub, M. L., Scott, S. C., Neibauer, T. L., Salter, W. F., Creer, M. H., Zhu, Y., Bornhorst, J. A., Theobald, J. P., Algeciras-Schimnich, A., Cao, L., Knox, J., Hardy, R., Texas, H. J., McGuire, M. F., Hunter, R. L., Brown, R. E., Hicks, J., Cai, Z., Brown, R. E., Ali, Y., Cheng, K. C., Katz, S. R., Ding, Y., Vanselow, D. J., Yakovlev, M. A., Lin, A. Y., Clark, D. P., Vargas, P., Xin, X., Copper, J. E., Canfield, V. A., Ang, K. C., Wang, Y., Xiao, X., De Carlo, F., van Rossum, D. B., La Rivière, P. J., Newell, J., Hossler, C., Roche, M., Warrick, J., Phaeton, R., Kesterson, J., Myers, C., Barrios, R., Mintz, P., Robyak, K., Hamilton, C., McGhee, P., Pederson, C., Straub, M., Scott, S., Neibauer, T., Salter, W., Robyak, K., Singh, N., Morlote, D., Vnencak-Jones, C., Yemelyanova, A., Harada, S., Shah, M., Moghadamtousi, S. Z., Lan, C., Duose, D., Hu, P., Esquenazi, Y., Luthra, R., Ballester, L. Y., Koenig, A. N., Liu, C. G., Zhang, J., Kalia, A., Al-Habib, A., Van Arsdall, M., Dhingra, S., Patel, K. & Tatevian, N., May 1 2019, In : Annals of clinical and laboratory science. 49, 3, p. 403-416 14 p.

Research output: Contribution to journalArticle

Advanced NSCLC patients with high IL-6 levels have altered peripheral T cell population and signaling

Rice, S. J., Liu, X., Zhang, J., Jia, B., Zheng, H. & Belani, C. P., May 2019, In : Lung Cancer. 131, p. 58-61 4 p.

Research output: Contribution to journalArticle

A global scientific strategy to cure hepatitis B

Members of the ICE-HBV Working Groups, ICE-HBV Stakeholders Group Chairs & ICE-HBV Senior Advisors, Jul 2019, In : The Lancet Gastroenterology and Hepatology. 4, 7, p. 545-558 14 p.

Research output: Contribution to journalComment/debate

34 Scopus citations

Aldehyde dehydrogenase in regulatory T-cell development, immunity and cancer

Bazewicz, C. G., Dinavahi, S. S., Schell, T. D. & Robertson, G. P., Jan 2019, In : Immunology. 156, 1, p. 47-55 9 p.

Research output: Contribution to journalReview article

9 Scopus citations

Asymmetry in icosahedral viruses

Goetschius, D. J., Parrish, C. R. & Hafenstein, S., Jun 2019, In : Current Opinion in Virology. 36, p. 67-73 7 p.

Research output: Contribution to journalReview article

1 Scopus citations

A trip down memory lane with Retrovirology

Benkirane, M., Berkhout, B., Borrow, P., Fassati, A., Fujii, M., Garcia-Martinez, J. V., Margolis, D., Nijhuis, M., Parent, L., Strebel, K., Venter, F., Kirchhoff, F., Lever, A., Ross, S. & Mak, J., Aug 21 2019, In : Retrovirology. 16, 1, 22.

Research output: Contribution to journalReview article

Open Access

Author Correction: The wide utility of rabbits as models of human diseases (Experimental & Molecular Medicine, (2018), 50, 5, (66), 10.1038/s12276-018-0094-1)

Esteves, P. J., Abrantes, J., Baldauf, H. M., BenMohamed, L., Chen, Y., Christensen, N., González-Gallego, J., Giacani, L., Hu, J., Kaplan, G., Keppler, O. T., Knight, K. L., Kong, X. P., Lanning, D. K., Le Pendu, J., de Matos, A. L., Liu, J., Liu, S., Lopes, A. M., Lu, S. & 17 others, Lukehart, S., Manabe, Y. C., Neves, F., McFadden, G., Pan, R., Peng, X., de Sousa-Pereira, P., Pinheiro, A., Rahman, M., Ruvoën-Clouet, N., Subbian, S., Tuñón, M. J., van der Loo, W., Vaine, M., Via, L. E., Wang, S. & Mage, R., Jul 1 2019, In : Experimental and Molecular Medicine. 51, 7, 71.

Research output: Contribution to journalComment/debate

Open Access
2 Scopus citations

Cell and Animal Models for Studying Hepatitis B Virus Infection and Drug Development

Hu, J., Lin, Y. Y., Chen, P. J., Watashi, K. & Wakita, T., Jan 2019, In : Gastroenterology. 156, 2, p. 338-354 17 p.

Research output: Contribution to journalArticle

11 Scopus citations

Chemical pressure effect on the optical conductivity of the nodal-line semimetals ZrSiY (Y= S,Se,Te) and ZrGeY (Y= S,Te)

Ebad-Allah, J., Afonso, J. F., M., K., Hu, J., Zhu, Y. L., Mao, Z. Q., J., K. & Kuntscher, C. A., 2019, In : Physical Review B. 99, 12

Research output: Contribution to journalArticle

6 Scopus citations

Components of the reovirus capsid differentially contribute to stability

Snyder, A. J., Wang, J. C. Y. & Danthi, P., Jan 1 2019, In : Journal of virology. 93, 2, e01894-18.

Research output: Contribution to journalArticle

1 Scopus citations

CryoEM reconstruction approaches to resolve asymmetric features

Goetschius, D. J., Lee, H. & Hafenstein, S., 2019, Advances in Virus Research. Rey, F. A. (ed.). Academic Press Inc., p. 73-91 19 p. (Advances in Virus Research; vol. 105).

Research output: Chapter in Book/Report/Conference proceedingChapter

Customizing an electronic medical record to automate the workflow and tracking of an antimicrobial stewardship program

Katzman, M., Kim, J., Lesher, M. D., Hale, C. M., McSherry, G. D., Loser, M. F., Ward, M. A. & Glasser, F. D., Jun 3 2019, In : Open Forum Infectious Diseases. 6, 8, p. 1-9 9 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations
1 Scopus citations

Dissecting the Components of Sindbis Virus from Arthropod and Vertebrate Hosts: Implications for Infectivity Differences

Dunbar, C. A., Rayaprolu, V., Wang, J. C. Y., Brown, C. J., Leishman, E., Jones-Burrage, S., Trinidad, J. C., Bradshaw, H. B., Clemmer, D. E., Mukhopadhyay, S. & Jarrold, M. F., Jun 14 2019, In : ACS Infectious Diseases. 5, 6, p. 892-902 11 p.

Research output: Contribution to journalArticle

3 Scopus citations

Downregulation of CD73 associates with T cell exhaustion in AML patients

Kong, Y., Jia, B., Zhao, C., Claxton, D. F., Sharma, A., Annageldiyev, C., Fotos, J. S., Zeng, H., Paulson, R. F., Prabhu, K. S. & Zheng, H., Apr 24 2019, In : Journal of Hematology and Oncology. 12, 1, 40.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations
Open Access
4 Scopus citations

Examination and reconstruction of three ancient endogenous parvovirus capsid protein gene remnants found in rodent genomes

Callaway, H. M., Subramanian, S., Urbina, C. A., Barnard, K. N., Dick, R. A., Bator, C. M., Hafenstein, S. L., Gifford, R. J. & Parrish, C. R., Mar 1 2019, In : Journal of virology. 93, 6, e01542-18.

Research output: Contribution to journalArticle

1 Scopus citations

Filling Adeno-Associated Virus Capsids: Estimating Success by Cryo-Electron Microscopy

Subramanian, S., Maurer, A. C., Bator, C. M., Makhov, A. M., Conway, J. F., Turner, K. B., Marden, J. H., Vandenberghe, L. H. & Hafenstein, S. L., Dec 2019, In : Human Gene Therapy. 30, 12, p. 1449-1460 12 p.

Research output: Contribution to journalArticle

Genome-wide profiling of cervical rna-binding proteins identifies human papillomavirus regulation of rnaseh2a expression by viral e7 and e2f1

Xu, J., Liu, H., Yang, Y., Wang, X., Liu, P., Li, Y., Meyers, C., Banerjee, N. S., Wang, H. K., Cam, M., Lu, W., Chow, L. T., Xie, X., Zhu, J. & Zheng, Z. M., Jan 1 2019, In : mBio. 10, 1, e02687-18.

Research output: Contribution to journalArticle

12 Scopus citations

Glycoprotein D of HSV-1 is dependent on tegument protein UL16 for packaging and contains a motif that is differentially required for syncytia formation

Carmichael, J. C., Starkey, J., Zhang, D., Sarfo, A., Chadha, P., Wills, J. W. & Han, J., Jan 15 2019, In : Virology. 527, p. 64-76 13 p.

Research output: Contribution to journalArticle

2 Scopus citations

GPx3 supports ovarian cancer progression by manipulating the extracellular redox environment

Worley, B. L., Kim, Y. S., Mardini, J., Zaman, R., Leon, K. E., Vallur, P. G., Nduwumwami, A., Warrick, J. I., Timmins, P. F., Kesterson, J. P., Phaëton, R., Lee, N. Y., Walter, V., Endres, L., Mythreye, K., Aird, K. M. & Hempel, N., Jul 2019, In : Redox Biology. 25, 101051.

Research output: Contribution to journalArticle

5 Scopus citations

HIV–HBV and HIV–HCV coinfection and liver cancer development

Hu, J., Liu, K. & Luo, J., Jan 1 2019, Cancer Treatment and Research. Springer International Publishing, p. 231-250 20 p. (Cancer Treatment and Research; vol. 177).

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Scopus citations

Increased circulating microparticles in streptozotocin-induced diabetes propagate inflammation contributing to microvascular dysfunction

Feng, Q., Stork, C. J., Xu, S., Yuan, D., Xia, X., LaPenna, K. B., Guo, G., Sun, H., Xu, L. C., Siedlecki, C. A., Brundage, K. M., Sheaffer, N., Schell, T. D. & He, P., Feb 1 2019, In : Journal of Physiology. 597, 3, p. 781-798 18 p.

Research output: Contribution to journalArticle

1 Scopus citations

Inhibition of diverse opportunistic viruses by structurally optimized retrograde trafficking inhibitors

Desai, D., Lauver, M., Ostman, A., Cruz, L., Ferguson, K., Jin, G., Roper, B., Brosius, D., Lukacher, A., Amin, S. & Buchkovich, N., May 1 2019, In : Bioorganic and Medicinal Chemistry. 27, 9, p. 1795-1803 9 p.

Research output: Contribution to journalArticle

1 Scopus citations

Intestinal epithelial tight junction barrier regulation by autophagy-related protein ATG6/beclin 1

Wong, M., Ganapathy, A. S., Suchanec, E., Laidler, L., Ma, T. & Nighot, P., May 2019, In : American Journal of Physiology - Cell Physiology. 316, 5, p. C753-C765

Research output: Contribution to journalArticle

2 Scopus citations

Investigating intestinal permeability and gut microbiota roles in acute coronary syndrome patients

Alhmoud, T., Kumar, A., Lo, C. C., Al-Sadi, R., Clegg, S., Alomari, I., Zmeili, T., Gleasne, C. D., Mcmurry, K., Dichosa, A. E. K., Vuyisich, M., Chain, P. S. G., Mishra, S. & Ma, T., Aug 2019, In : Human Microbiome Journal. 13, 100059.

Research output: Contribution to journalArticle

Open Access

Lipopolysaccharide-Induced Increase in Intestinal Permeability Is Mediated by TAK-1 Activation of IKK and MLCK/MYLK Gene

Nighot, M., Rawat, M., Al-Sadi, R., Castillo, E. F., Nighot, P. & Ma, T. Y., Apr 2019, In : American Journal of Pathology. 189, 4, p. 797-812 16 p.

Research output: Contribution to journalArticle

5 Scopus citations

MEF-2 isoforms' (A-D) roles in development and tumorigenesis

Madugula, K., Mulherkar, R., Khan, Z. K., Chigbu, D. G. I., Patel, D., Harhaj, E. W. & Jain, P., Apr 12 2019, In : Oncotarget. 10, 28, p. 2755-2787 33 p.

Research output: Contribution to journalReview article

Open Access
1 Scopus citations

Milk-derived miRNA profiles elucidate molecular pathways that underlie breast dysfunction in women with common genetic variants in SLC30A2

Kelleher, S. L., Gagnon, A., Rivera, O. C., Hicks, S. D., Carney, M. C. & Alam, S., Dec 1 2019, In : Scientific reports. 9, 1, 12686.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

MMP-9-induced increase in intestinal epithelial tight permeability is mediated by p38 kinase signaling pathway activation of MLCK gene

Al-Sadi, R., Youssef, M., Rawat, M., Guo, S., Dokladny, K., Haque, M., Watterson, M. D. & Ma, T. Y., Feb 2019, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 316, 2, p. G278-G290

Research output: Contribution to journalArticle

2 Scopus citations