Department of Microbiology and Immunology

  • United States

Research Output

2017

Blimp-1 impairs T cell function via upregulation of TIGIT and PD-1 in patients with acute myeloid leukemia

Zhu, L., Kong, Y., Zhang, J., Claxton, D. F., Ehmann, W. C., Rybka, W. B., Palmisiano, N. D., Wang, M., Jia, B., Bayerl, M., Schell, T. D., Hohl, R. J., Zeng, H. & Zheng, H., Jun 19 2017, In : Journal of Hematology and Oncology. 10, 1, 124.

Research output: Contribution to journalArticle

15 Scopus citations

Capsid phosphorylation state and hepadnavirus virion secretion

Ning, X., Basagoudanavar, S. H., Liu, K., Luckenbaugh, L., Wei, D., Wang, C., Wei, B., Zhao, Y., Yan, T., Delaney, W. & Hu, J., May 1 2017, In : Journal of virology. 91, 9, e00092-17.

Research output: Contribution to journalArticle

18 Scopus citations

Chimeric L2-based virus-like particle (VLP) vaccines targeting cutaneous human papillomaviruses (HPV)

Huber, B., Schellenbacher, C., Shafti-Keramat, S., Jindra, C., Christensen, N. & Kirnbauer, R., Jan 2017, In : PloS one. 12, 1, 0169533.

Research output: Contribution to journalArticle

20 Scopus citations
11 Scopus citations
10 Scopus citations

C‐Myc‐induced survivin is essential for promoting the Notch-dependent t cell differentiation from hematopoietic stem cells

Haque, R., Song, J., Haque, M., Lei, F., Sandhu, P., Ni, B., Zheng, S., Fang, D., Yang, J. M. & Song, J., Mar 2017, In : Genes. 8, 3, 97.

Research output: Contribution to journalArticle

6 Scopus citations

Complete and incomplete hepatitis B virus particles: Formation, function, and application

Hu, J. & Liu, K., Mar 21 2017, In : Viruses. 9, 3, 56.

Research output: Contribution to journalReview article

68 Scopus citations

Compliance with Clostridium difficile treatment guidelines: Effect on patient outcomes

Crowell, K. T., Julian, K. G., Katzman, M., Berg, A. S., Tinsley, A., Williams, E. D., Koltun, W. A. & Messaris, E., Aug 1 2017, In : Epidemiology and Infection. 145, 11, p. 2185-2192 8 p.

Research output: Contribution to journalArticle

10 Scopus citations

Cryoelectron Microscopy Maps of Human Papillomavirus 16 Reveal L2 Densities and Heparin Binding Site

Guan, J., Bywaters, S. M., Brendle, S. A., Ashley, R. E., Makhov, A. M., Conway, J. F., Christensen, N. D. & Hafenstein, S., Feb 7 2017, In : Structure. 25, 2, p. 253-263 11 p.

Research output: Contribution to journalArticle

25 Scopus citations

Cryo-EM maps reveal five-fold channel structures and their modification by gatekeeper mutations in the parvovirus minute virus of mice (MVM) capsid

Subramanian, S., Organtini, L. J., Grossman, A., Domeier, P. P., Cifuente, J. O., Makhov, A. M., Conway, J. F., D'Abramo, A., Cotmore, S. F., Tattersall, P. & Hafenstein, S., Oct 2017, In : Virology. 510, p. 216-223 8 p.

Research output: Contribution to journalArticle

4 Scopus citations

Development and characterization of naive single-type tumor antigen-specific CD8+ T lymphocytes from murine pluripotent stem cells

Lei, F., Haque, M., Sandhu, P., Ravi, S., Song, J., Ni, B., Zheng, S., Fang, D., Jia, H., Yang, J. M. & Song, J., Jul 3 2017, In : OncoImmunology. 6, 7, e1334027.

Research output: Contribution to journalArticle

2 Scopus citations

Domain interaction studies of herpes simplex virus 1 tegument protein UL16 reveal its interaction with mitochondria

Chadha, P., Sarfo, A., Zhang, D., Abraham, T., Carmichael, J., Han, J. & Wills, J. W., Jan 1 2017, In : Journal of virology. 91, 2, e01995-16.

Research output: Contribution to journalArticle

5 Scopus citations
6 Scopus citations

Endophilin B2 facilitates endosome maturation in response to growth factor stimulation, autophagy induction, and influenza A virus infection

Serfass, J. M., Takahashi, Y., Zhou, Z., Kawasawa, Y. I., Liu, Y., Tsotakos, N., Young, M. M., Tang, Z., Yang, L., Atkinson, J. M., Chroneos, Z. C. & Wang, H. G., Jun 16 2017, In : Journal of Biological Chemistry. 292, 24, p. 10097-10111 15 p.

Research output: Contribution to journalArticle

7 Scopus citations

Erratum: Merkel cell polyomavirus small T antigen induces genome instability by E3 ubiquitin ligase targeting (Oncogene (2017))

Kwun, H. J., Wendzicki, J. A., Shuda, Y., Moore, P. S. & Chang, Y., Dec 7 2017, In : Oncogene. 36, 49, 1 p.

Research output: Contribution to journalComment/debate

Open Access

Evolution and cryo-electron microscopy capsid structure of a north american bat adenovirus and its relationship to other mastadenoviruses

Hackenbrack, N., Rogers, M. B., Ashley, R. E., Keel, M. K., Kubiski, S. V., Bryan, J. A., Ghedin, E., Holmes, E. C., Hafenstein, S. L. & Allison, A. B., Jan 1 2017, In : Journal of virology. 91, 2, e01504-16.

Research output: Contribution to journalArticle

13 Scopus citations

Generation and infection of organotypic cultures with Epstein-Barr virus

Temple, R. M., Meyers, C. & Sample, C. E., Jan 1 2017, Methods in Molecular Biology. Humana Press Inc., p. 65-78 14 p. (Methods in Molecular Biology; vol. 1532).

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Hepatitis B virus immunopathology, model systems, and current therapies

Sandhu, P., Haque, M., Humphries-Bickley, T., Ravi, S. & Song, J., Apr 13 2017, In : Frontiers in immunology. 8, APR, 436.

Research output: Contribution to journalReview article

9 Scopus citations

High-resolution structure analysis of antibody V5 and U4 conformational epitopes on human papillomavirus 16

Guan, J., Bywaters, S. M., Brendle, S. A., Ashley, R. E., Makhov, A. M., Conway, J. F., Christensen, N. D. & Hafenstein, S., Dec 6 2017, In : Viruses. 9, 12, 374.

Research output: Contribution to journalArticle

2 Scopus citations

Honey bee deformed wing virus structures reveal that conformational changes accompany genome release

Organtini, L. J., Shingler, K. L., Ashley, R. E., Capaldi, E. A., Durrani, K., Dryden, K. A., Makhov, A. M., Conway, J. F., Pizzorno, M. C. & Hafenstein, S., Jan 1 2017, In : Journal of virology. 91, 2, e01795-16.

Research output: Contribution to journalArticle

10 Scopus citations

HVEM imprints memory potential on effector CD8 T cells required for protective mucosal immunity

Desai, P., Abboud, G., Stanfield, J., Thomas, P. G., Song, J., Ware, C. F., Croft, M. & Salek-Ardakani, S., Oct 15 2017, In : Journal of Immunology. 199, 8, p. 2968-2975 8 p.

Research output: Contribution to journalArticle

6 Scopus citations

Identification of an intermediate in hepatitis B virus covalently closed circular (CCC) DNA formation and sensitive and selective CCC DNA detection

Luo, J., Cui, X., Gao, L. & Hu, J., Sep 1 2017, In : Journal of virology. 91, 17, e00539-17.

Research output: Contribution to journalArticle

16 Scopus citations
52 Scopus citations

Incorporation of RG1 epitope concatemers into a self-adjuvanting Flagellin-L2 vaccine broaden durable protection against cutaneous challenge with diverse human papillomavirus genotypes

Kalnin, K., Chivukula, S., Tibbitts, T., Yan, Y., Stegalkina, S., Shen, L., Cieszynski, J., Costa, V., Sabharwal, R., Anderson, S. F., Christensen, N., Jagu, S., Roden, R. B. S. & Kleanthous, H., Sep 5 2017, In : Vaccine. 35, 37, p. 4942-4951 10 p.

Research output: Contribution to journalArticle

8 Scopus citations

Inhibition of retrograde transport limits polyomavirus infection in vivo

Maru, S., Jin, G., Desai, D., Amin, S., Shwetank, Lauver, M. D. & Lukacher, A. E., Nov 1 2017, In : mSphere. 2, 6, e00494-17.

Research output: Contribution to journalArticle

7 Scopus citations

Insights into the dichotomous regulation of SOD2 in cancer

Kim, Y. S., Vallur, P. G., Phaëton, R., Mythreye, K. & Hempel, N., Dec 2017, In : Antioxidants. 6, 4, 86.

Research output: Contribution to journalReview article

27 Scopus citations

In vitro assays for RNA binding and protein priming of hepatitis B virus polymerase

Clark, D. N., Jones, S. A. & Hu, J., Jan 1 2017, Methods in Molecular Biology. Humana Press Inc., p. 157-177 21 p. (Methods in Molecular Biology; vol. 1540).

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Length of encapsidated cargo impacts stability and structure of in vitro assembled alphavirus core-like particles

Rayaprolu, V., Moore, A., Wang, J. C. Y., Goh, B. C., Perilla, J. R., Zlotnick, A. & Mukhopadhyay, S., Nov 10 2017, In : Journal of Physics Condensed Matter. 29, 48, 484003.

Research output: Contribution to journalArticle

9 Scopus citations
26 Scopus citations

Local amplifiers of IL-4Ra-mediated macrophage activation promote repair in lung and liver

Minutti, C. M., Jackson-Jones, L. H., García-Fojeda, B., Knipper, J. A., Sutherland, T. E., Logan, N., Rinqvist, E., Guillamat-Prats, R., Ferenbach, D. A., Artigas, A., Stamme, C., Chroneos, Z. C., Zaiss, D. M., Casals, C. & Allen, J. E., Jun 9 2017, In : Science. 356, 6342, p. 1076-1080 5 p.

Research output: Contribution to journalArticle

62 Scopus citations

Maintenance of PD-1 on brain-resident memory CD8 T cells is antigen independent

Shwetank, Abdelsamed, H. A., Frost, E. L., Schmitz, H. M., Mockus, T. E., Youngblood, B. A. & Lukacher, A. E., Nov 1 2017, In : Immunology and Cell Biology. 95, 10, p. 953-959 7 p.

Research output: Contribution to journalArticle

23 Scopus citations

Mapping of functional subdomains in the terminal protein domain of hepatitis B virus polymerase

Clark, D. N., Flanagan, J. M. & Hu, J., Jan 1 2017, In : Journal of virology. 91, 3, e01785-16.

Research output: Contribution to journalArticle

4 Scopus citations

Merkel cell polyomavirus small T antigen induces genome instability by E3 ubiquitin ligase targeting

Kwun, H. J., Wendzicki, J. A., Shuda, Y., Moore, P. S. & Chang, Y., Jan 1 2017, In : Oncogene. 36, 49, p. 6784-6792 9 p.

Research output: Contribution to journalArticle

19 Scopus citations

Mer receptor tyrosine kinase signaling prevents self-ligand sensing and aberrant selection in germinal centers

Schell, S. L., Soni, C., Fasnacht, M. J., Domeier, P. P., Cooper, T. K. & Rahman, Z. S. M., Dec 15 2017, In : Journal of Immunology. 199, 12, p. 4001-4015 15 p.

Research output: Contribution to journalArticle

2 Scopus citations

MOPS and coxsackievirus B3 stability

Carson, S. D., Hafenstein, S. & Lee, H., Jan 15 2017, In : Virology. 501, p. 183-187 5 p.

Research output: Contribution to journalArticle

1 Scopus citations

Mouse papillomavirus infection persists in mucosal tissues of an immunocompetent mouse strain and progresses to cancer

Cladel, N. M., Budgeon, L. R., Balogh, K. K., Cooper, T. K., Brendle, S. A., Christensen, N. D., Schell, T. D. & Hu, J., Dec 1 2017, In : Scientific reports. 7, 1, 16932.

Research output: Contribution to journalArticle

5 Scopus citations

Mouse papillomavirus infections spread to cutaneous sites with progression to malignancy

Cladel, N. M., Budgeon, L. R., Cooper, T. K., Balogh, K. K., Christensen, N. D., Myers, R., Majerciak, V., Gotte, D., Zheng, Z. M. & Hu, J., Oct 2017, In : Journal of General Virology. 98, 10, p. 2520-2529 10 p., 000926.

Research output: Contribution to journalArticle

6 Scopus citations

Mutations in HPV18 E1ˆE4 impact virus capsid assembly, infectivity competence, and maturation

Biryukov, J., Myers, J. C., McLaughlin-Drubin, M. E., Griffin, H. M., Milici, J., Doorbar, J. & Meyers, C., Dec 19 2017, In : Viruses. 9, 12, 385.

Research output: Contribution to journalArticle

2 Scopus citations

Nanoparticle-Programmed Surface for Drug Release and Cell Regulation via Reversible Hybridization Reaction

Jiang, P., Li, S., Lai, J., Zheng, H., Lin, C., Shi, P. & Wang, Y., Feb 8 2017, In : ACS Applied Materials and Interfaces. 9, 5, p. 4467-4474 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

Parvovirus capsid structures required for infection: Mutations controlling receptor recognition and protease cleavages

Callaway, H. M., Feng, K. H., Lee, D. W., Allison, A. B., Pinard, M., McKenna, R., Agbandje-McKenna, M., Hafenstein, S. & Parrish, C. R., Jan 1 2017, In : Journal of virology. 91, 2, e01871-16.

Research output: Contribution to journalArticle

9 Scopus citations

PD-1 blockade promotes epitope spreading in anticancer CD8+ T cell responses by preventing fratricidal death of subdominant clones to relieve immunodomination

Memarnejadian, A., Meilleur, C. E., Shaler, C. R., Khazaie, K., Bennink, J. R., Schell, T. D. & Haeryfar, S. M. M., Nov 1 2017, In : Journal of Immunology. 199, 9, p. 3348-3359 12 p.

Research output: Contribution to journalArticle

20 Scopus citations

Potent inhibition of human cytomegalovirus by modulation of cellular SNARE syntaxin 5

Cruz, L., Streck, N. T., Ferguson, K., Desai, T., Desai, D. H., Amin, S. G. & Buchkovich, N. J., Jan 1 2017, In : Journal of virology. 91, 1, e01637-16.

Research output: Contribution to journalArticle

11 Scopus citations

Protein-mediated viral latency is a novel mechanism for Merkel cell polyomavirus persistence

Kwun, H. J., Chang, Y. & Moore, P. S., May 16 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 20, p. E4040-E4047

Research output: Contribution to journalArticle

7 Scopus citations

Ranpirnase eradicates human papillomavirus in cultured cells and heals anogenital warts in a Phase i study

Squiquera, L., Taxman, D. J., Brendle, S. A., Torres, R., Sulley, J., Hodge, T., Christensen, N. & Sidransky, D., Jan 1 2017, In : Antiviral Therapy. 22, 3, p. 247-255 9 p.

Research output: Contribution to journalArticle

6 Scopus citations

Recent advances in preclinical model systems for papillomaviruses

Christensen, N. D., Budgeon, L. R., Cladel, N. M. & Hu, J., Mar 2 2017, In : Virus Research. 231, p. 108-118 11 p.

Research output: Contribution to journalReview article

12 Scopus citations

Reducing persistent polyomavirus infection increases functionality of virus-specific memory CD8 T cells

Qin, Q., Lauver, M., Maru, S., Lin, E. & Lukacher, A. E., Feb 1 2017, In : Virology. 502, p. 198-205 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

Regnase-1, a rapid response ribonuclease regulating inflammation and stress responses

Mao, R., Yang, R., Chen, X., Harhaj, E. W., Wang, X. & Fan, Y., May 1 2017, In : Cellular and Molecular Immunology. 14, 5, p. 412-422 11 p.

Research output: Contribution to journalReview article

10 Scopus citations

Rerouting the traffic from a virus perspective

Cruz, L. & Buchkovich, N. J., Jun 1 2017, In : Frontiers in Bioscience - Landmark. 22, 11, p. 1845-1866 22 p.

Research output: Contribution to journalReview article

3 Scopus citations

SH3GLB2/endophilin B2 regulates lung homeostasis and recovery from severe influenza A virus infection

Fino, K. K., Yang, L., Silveyra, P., Hu, S., Umstead, T. M., Diangelo, S., Halstead, E. S., Cooper, T. K., Abraham, T., Takahashi, Y., Zhou, Z., Wang, H. G. & Chroneos, Z. C., Dec 1 2017, In : Scientific reports. 7, 1, 7262.

Research output: Contribution to journalArticle

4 Scopus citations
4 Scopus citations