Department of Microbiology and Immunology

  • United States

Research Output

2015

Durable complete responses off all treatment in patients with metastatic malignant melanoma after sequential immunotherapy followed by a finite course of BRAF inhibitor therapy

Wyluda, E. J., Cheng, J., Schell, T. D., Haley, J. S., Mallon, C., Neves, R. I., Robertson, G., Sivik, J., Mackley, H., Talamo, G. & Drabick, J. J., Jan 1 2015, In : Cancer Biology and Therapy. 16, 5, p. 662-670 9 p.

Research output: Contribution to journalArticle

18 Scopus citations

Durable immunity to oncogenic human papillomaviruses elicited by adjuvanted recombinant Adeno-associated virus-like particle immunogen displaying L2 17-36 epitopes

Jagu, S., Karanam, B., Wang, J. W., Zayed, H., Weghofer, M., Brendle, S. A., Balogh, K. K., Tossi, K. P., Roden, R. B. S. & Christensen, N. D., Oct 13 2015, In : Vaccine. 33, 42, p. 5553-5563 11 p.

Research output: Contribution to journalArticle

13 Scopus citations

Elucidating dynamic protein–protein interactions and ubiquitination in NF-κB signaling pathways

Shembade, N. & Harhaj, E. W., Jan 1 2015, In : Methods in Molecular Biology. 1280, p. 283-295 13 p.

Research output: Contribution to journalArticle

3 Scopus citations

Essential role for zinc transporter 2 (ZnT2)-mediated zinc transport in mammary gland development and function during lactation

Lee, S., Hennigar, S. R., Alam, S., Nishida, K. & Kelleher, S. L., May 22 2015, In : Journal of Biological Chemistry. 290, 21, p. 13064-13078 15 p.

Research output: Contribution to journalArticle

43 Scopus citations

Exome Sequencing of SLC30A2 Identifies Novel Loss- and Gain-of-Function Variants Associated with Breast Cell Dysfunction

Alam, S., Hennigar, S. R., Gallagher, C., Soybel, D. I. & Kelleher, S. L., Aug 21 2015, In : Journal of mammary gland biology and neoplasia. 20, 3-4, p. 159-172 14 p.

Research output: Contribution to journalReview article

18 Scopus citations

Flagella-independent surface motility in Salmonella enterica serovar Typhimurium

Park, S. Y., Pontes, M. H. & Groisman, E. A., Feb 10 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 6, p. 1850-1855 6 p.

Research output: Contribution to journalArticle

18 Scopus citations

Gammaherpesvirus infection modulates the temporal and spatial expression of SCGB1A1 (CCSP) and BPIFA1 (SPLUNC1) in the respiratory tract

Leeming, G. H., Kipar, A., Hughes, D. J., Bingle, L., Bennett, E., Moyo, N. A., Tripp, R. A., Bigley, A. L., Bingle, C. D., Sample, J. T. & Stewart, J. P., Jun 28 2015, In : Laboratory Investigation. 95, 6, p. 610-624 15 p.

Research output: Contribution to journalArticle

4 Scopus citations

Genetic Ablation of the ClC-2 Cl-Channel disrupts mouse gastric parietal cell acid secretion

Nighot, M. P., Nighot, P. K., Ma, T. Y., Malinowska, D. H., Shull, G. E., Cuppoletti, J. & Blikslager, A. T., Sep 17 2015, In : PloS one. 10, 9, A1344.

Research output: Contribution to journalArticle

12 Scopus citations

Genome-free hepatitis B virion levels in patient sera as a potential marker to monitor response to antiviral therapy

Luckenbaugh, L., Kitrinos, K. M., Delaney, W. E. & Hu, J., Jun 1 2015, In : Journal of Viral Hepatitis. 22, 6, p. 561-570 10 p.

Research output: Contribution to journalArticle

39 Scopus citations

Global displacement of canine parvovirus by a host-adapted variant: Structural comparison between pandemic viruses with distinct host ranges

Organtini, L. J., Allison, A. B., Lukk, T., Parrish, C. R. & Hafenstein, S., Jan 1 2015, In : Journal of virology. 89, 3, p. 1909-1912 4 p.

Research output: Contribution to journalArticle

26 Scopus citations

Group Selection and Contribution of Minority Variants during Virus Adaptation Determines Virus Fitness and Phenotype

Bordería, A. V., Isakov, O., Moratorio, G., Henningsson, R., Agüera-González, S., Organtini, L., Gnädig, N. F., Blanc, H., Alcover, A., Hafenstein, S., Fontes, M., Shomron, N. & Vignuzzi, M., May 1 2015, In : PLoS pathogens. 11, 5, e1004838.

Research output: Contribution to journalArticle

60 Scopus citations

Hepadnavirus genome replication and persistence

Hu, J. & Seeger, C., Jul 1 2015, In : Cold Spring Harbor Perspectives in Medicine. 5, 7

Research output: Contribution to journalArticle

45 Scopus citations

Hepatitis B virus core protein phosphorylation sites affect capsid stability and transient exposure of the C-terminal domain

Selzer, L., Kant, R., Wang, J. C. Y., Bothner, B. & Zlotnick, A., Nov 20 2015, In : Journal of Biological Chemistry. 290, 47, p. 28584-28593 10 p.

Research output: Contribution to journalArticle

Open Access
32 Scopus citations

Hepatitis B virus covalently closed circular DNA formation in immortalized mouse hepatocytes associated with nucleocapsid destabilization

Cui, X., Guo, J. T. & Hu, J., Jan 1 2015, In : Journal of virology. 89, 17, p. 9021-9028 8 p.

Research output: Contribution to journalArticle

29 Scopus citations

Hepatitis B virus reverse transcriptase - Target of current antiviral therapy and future drug development

Clark, D. N. & Hu, J., Nov 1 2015, In : Antiviral Research. 123, p. 132-137 6 p.

Research output: Contribution to journalReview article

40 Scopus citations

High incidence of spontaneous cataracts in aging laboratory rabbits of an inbred strain

Peng, X., Roshwalb, S., Cooper, T. K., Zimmerman, H. & Christensen, N. D., May 1 2015, In : Veterinary Ophthalmology. 18, 3, p. 186-190 5 p.

Research output: Contribution to journalArticle

8 Scopus citations

HPV binding assay to laminin-332/integrin α6β4 on human keratinocytes

Brendle, S. A. & Christensen, N. D., Jan 1 2015, In : Methods in Molecular Biology. 1249, p. 53-66 14 p.

Research output: Contribution to journalArticle

2 Scopus citations
5 Scopus citations

Intestinal Monocyte-Derived Macrophages Control Commensal-Specific Th17 Responses

Panea, C., Farkas, A. M., Goto, Y., Abdollahi-Roodsaz, S., Lee, C., Koscsó, B., Gowda, K., Hohl, T. M., Bogunovic, M. & Ivanov, I. I., Aug 25 2015, In : Cell Reports. 12, 8, p. 1314-1324 11 p., 1940.

Research output: Contribution to journalArticle

61 Scopus citations

Keratin-dependent regulation of Aire and gene expression in skin tumor keratinocytes

Hobbs, R., Depianto, D. J., Jacob, J. T., Han, M. C., Chung, B. M., Batazzi, A. S., Poll, B. G., Guo, Y., Han, J., Ong, S., Zheng, W., Taube, J. M., Ciháková, D., Wan, F. & Coulombe, P. A., Aug 30 2015, In : Nature Genetics. 47, 8, p. 933-938 6 p.

Research output: Contribution to journalArticle

50 Scopus citations

Laboratory Evaluation of Hemolysis and Systemic Inflammatory Response in Neonatal Nonpulsatile and Pulsatile Extracorporeal Life Support Systems

Wang, S., Krawiec, C., Patel, S., Kunselman, A. R., Song, J., Lei, F., Baer, L. D. & Ündar, A., Sep 1 2015, In : Artificial organs. 39, 9, p. 774-781 8 p.

Research output: Contribution to journalArticle

28 Scopus citations

Lethal influenza infection: Is a macrophage to blame?

Halstead, E. S. & Chroneos, Z. C., Dec 2 2015, In : Expert Review of Anti-Infective Therapy. 13, 12, p. 1425-1428 4 p.

Research output: Contribution to journalReview article

5 Scopus citations
86 Scopus citations
41 Scopus citations

Myocyte enhancer factor (MEF)-2 plays essential roles in T-cell transformation associated with HTLV-1 infection by stabilizing complex between Tax and CREB

Jain, P., Lavorgna, A., Sehgal, M., Gao, L., Ginwala, R., Sagar, D., Harhaj, E. W. & Khan, Z. K., Feb 27 2015, In : Retrovirology. 12, 1, 23.

Research output: Contribution to journalArticle

5 Scopus citations

Naive and radiolabeled antibodies to E6 and E7 HPV-16 oncoproteins show pronounced antitumor activity in experimental cervical cancer

Phaëton, R., Gutierrez, J., Jiang, Z., Karabakhtsian, R. G., Albanese, J., Sunkara, J., Fisher, D. R., Goldberg, G. L. & Dadachova, E., Jul 1 2015, In : Immunotherapy. 7, 6, p. 631-640 10 p.

Research output: Contribution to journalArticle

5 Scopus citations

Native human papillomavirus production, quantification, and infectivity analysis

Biryukov, J., Cruz, L., Ryndock, E. J. & Meyers, C., Jan 1 2015, In : Methods in Molecular Biology. 1249, p. 317-331 15 p.

Research output: Contribution to journalArticle

5 Scopus citations

Oncogenic human T-cell lymphotropic virus type 1 tax suppression of primary innate immune signaling pathways

Hyun, J., Ramos, J. C., Toomey, N., Balachandran, S., Lavorgna, A., Harhaj, E. & Barber, G. N., Jan 1 2015, In : Journal of virology. 89, 9, p. 4880-4893 14 p.

Research output: Contribution to journalArticle

13 Scopus citations

Papillomavirus infectious pathways: A comparison of systems

Biryukov, J. & Meyers, C., Aug 4 2015, In : Viruses. 7, 8, p. 4303-4325 23 p.

Research output: Contribution to journalReview article

14 Scopus citations

Pathogen stimulation history impacts donor-specific CD8+ T cell susceptibility to costimulation/integrin blockade-based therapy

Badell, I. R., Kitchens, W. H., Wagener, M. E., Lukacher, A. E., Larsen, C. P. & Ford, M. L., Dec 2015, In : American Journal of Transplantation. 15, 12, p. 3081-3094 14 p.

Research output: Contribution to journalArticle

9 Scopus citations
56 Scopus citations

Peptide-MHC-I from Endogenous Antigen Outnumber Those from Exogenous Antigen, Irrespective of APC Phenotype or Activation

Sei, J. J., Haskett, S., Kaminsky, L. W., Lin, E., Truckenmiller, M. E., Bellone, C. J., Buller, R. M. & Norbury, C. C., Jun 1 2015, In : PLoS pathogens. 11, 6, e1004941.

Research output: Contribution to journalArticle

16 Scopus citations
2 Scopus citations

Purification of dendritic cell and macrophage subsets from the normal mouse small intestine

Koscsó, B., Gowda, K., Schell, T. D. & Bogunovic, M., Jun 1 2015, In : Journal of Immunological Methods. 421, p. 1-13 13 p.

Research output: Contribution to journalArticle

12 Scopus citations

Randomized controlled trial of oral glutathione supplementation on body stores of glutathione

Richie, J. P., Nichenametla, S., Neidig, W., Calcagnotto, A., Haley, J. S., Schell, T. D. & Muscat, J. E., Jan 1 2015, In : European Journal of Nutrition. 54, 2, p. 251-263 13 p.

Research output: Contribution to journalArticle

30 Scopus citations

Redundant function of plasmacytoid and conventional dendritic cells is required to survive a natural virus infection

Kaminsky, L. W., Sei, J. J., Parekh, N. J., Davies, M. L., Reider, I. E., Krouse, T. E. & Norbury, C. C., Jan 1 2015, In : Journal of virology. 89, 19, p. 9974-9985 12 p.

Research output: Contribution to journalArticle

7 Scopus citations

Regulation of multiple stages of hepadnavirus replication by the carboxyl-terminal domain of viral core protein in trans

Liu, K., Ludgate, L., Yuan, Z. & Hu, J., Jan 1 2015, In : Journal of virology. 89, 5, p. 2918-2930 13 p.

Research output: Contribution to journalArticle

22 Scopus citations

Replication of human papillomavirus in culture

Ryndock, E. J., Biryukov, J. & Meyers, C., Jan 1 2015, In : Methods in molecular biology (Clifton, N.J.). 1249, p. 39-52 14 p.

Research output: Contribution to journalArticle

Replication of human papillomavirus in culture

Ryndock, E. J., Biryukov, J. & Meyers, C., Jan 1 2015, In : Methods in Molecular Biology. 1249, p. 39-52 14 p.

Research output: Contribution to journalArticle

5 Scopus citations

Restricted protein phosphatase 2A targeting by merkel cell polyomavirus small T antigen

Kwun, H. J., Shuda, M., Camacho, C. J., Gamper, A. M., Thant, M., Chang, Y. & Moore, P. S., Jan 1 2015, In : Journal of virology. 89, 8, p. 4191-4200 10 p.

Research output: Contribution to journalArticle

28 Scopus citations

Salmonella promotes virulence by repressing cellulose production

Pontes, M. H., Lee, E. J., Choi, J. & Groisman, E. A., Apr 21 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 16, p. 5183-5188 6 p.

Research output: Contribution to journalArticle

50 Scopus citations

Self-assembling virus-like and virus-unlike particles

Zlotnick, A., Francis, S., Lee, L. S. & Wang, J. C. Y., Jan 1 2015, Viral Nanotechnology. CRC Press, p. 13-26 14 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations

Self-Assembly of an Alphavirus Core-like Particle Is Distinguished by Strong Intersubunit Association Energy and Structural Defects

Wang, J. C. Y., Chen, C., Rayaprolu, V., Mukhopadhyay, S. & Zlotnick, A., Sep 22 2015, In : ACS nano. 9, 9, p. 8898-8906 9 p.

Research output: Contribution to journalArticle

15 Scopus citations

Sex differences in the expression of lung inflammatory mediators in response to ozone

Cabello, N., Mishra, V., Sinha, U., Diangelo, S. L., Chroneos, Z. C., Ekpa, N. A., Cooper, T. K., Caruso, C. R. & Silveyra, P., Jan 1 2015, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 309, 10, p. L1150-L1163

Research output: Contribution to journalArticle

28 Scopus citations

Specificity of coxsackievirus B3 interaction with human, but not murine, decay-accelerating factor: Replacement of a single residue within short consensus repeat 2 prevents virus attachment

Pan, J., Zhang, L., Organtini, L., Hafenstein, S. & Bergelson, J. M., Jan 1 2015, In : Journal of virology. 89, 2, p. 1324-1328 5 p.

Research output: Contribution to journalArticle

2 Scopus citations

SP-R210 (Myo18A) isoforms as intrinsic modulators of macrophage priming and activation

Yang, L., Carrillo, M., Wu, Y. M., DiAngelo, S. L., Silveyra, P., Umstead, T. M., Halstead, E. S., Davies, M. L., Hu, S., Floros, J., McCormack, F. X., Christensen, N. D. & Chroneos, Z. C., May 12 2015, In : PloS one. 10, 5, e0126576.

Research output: Contribution to journalArticle

9 Scopus citations

Structural basis for activation, assembly and membrane binding of ESCRT-III Snf7 filaments

Tang, S., Henne, W. M., Borbat, P. P., Buchkovich, N. J., Freed, J. H., Mao, Y., Fromme, J. C. & Emr, S. D., Dec 15 2015, In : eLife. 4, DECEMBER2015, e12548.

Research output: Contribution to journalArticle

46 Scopus citations

Structural comparison of four different antibodies interacting with human papillomavirus 16 and mechanisms of neutralization

Guan, J., Bywaters, S. M., Brendle, S. A., Lee, H., Ashley, R. E., Makhov, A. M., Conway, J. F., Christensen, N. & Hafenstein, S., Sep 1 2015, In : Virology. 483, p. 253-263 11 p.

Research output: Contribution to journalArticle

29 Scopus citations

The enterovirus 71 procapsid binds neutralizing antibodies and rescues virus infection in vitro

Shingler, K. L., Cifuente, J. O., Ashley, R. E., Makhov, A. M., Conway, J. F. & Hafenstein, S., Jan 1 2015, In : Journal of virology. 89, 3, p. 1900-1908 9 p.

Research output: Contribution to journalArticle

17 Scopus citations