Department of Microbiology and Immunology

  • United States

Research Output 1979 2019

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Review article
2019
6 Citations (Scopus)

Aldehyde dehydrogenase in regulatory T-cell development, immunity and cancer

Bazewicz, C. G., Dinavahi, S. S., Schell, T. D. & Robertson, G. P., Jan 2019, In : Immunology. 156, 1, p. 47-55 9 p.

Research output: Contribution to journalReview article

Aldehyde Dehydrogenase
Regulatory T-Lymphocytes
Immunity
Neoplasms
Immune Tolerance

Asymmetry in icosahedral viruses

Goetschius, D. J., Parrish, C. R. & Hafenstein, S., Jun 1 2019, In : Current Opinion in Virology. 36, p. 67-73 7 p.

Research output: Contribution to journalReview article

Leviviridae
Genome
Viruses
Picornaviridae
Capsid Proteins

A trip down memory lane with Retrovirology

Benkirane, M., Berkhout, B., Borrow, P., Fassati, A., Fujii, M., Garcia-Martinez, J. V., Margolis, D., Nijhuis, M., Parent, L., Strebel, K., Venter, F., Kirchhoff, F., Lever, A., Ross, S. & Mak, J., Aug 21 2019, In : Retrovirology. 16, 1, 22.

Research output: Contribution to journalReview article

Open Access

MEF-2 isoforms' (A-D) roles in development and tumorigenesis

Madugula, K., Mulherkar, R., Khan, Z. K., Chigbu, D. G. I., Patel, D., Harhaj, E. W. & Jain, P., Apr 12 2019, In : Oncotarget. 10, 28, p. 2755-2787 33 p.

Research output: Contribution to journalReview article

Open Access
MEF2 Transcription Factors
Protein Isoforms
Carcinogenesis
Transcription Factors
Histone Deacetylases
1 Citation (Scopus)

Revisiting Hepatitis B virus: Challenges of curative therapies

Hu, J., Protzer, U. & Siddiqui, A., Oct 1 2019, In : Journal of virology. 93, 20, e01032-19.

Research output: Contribution to journalReview article

Hepatitis B virus
circular DNA
Circular DNA
therapeutics
Antiviral Agents

Secretion of empty or complete hepatitis B virions: Envelopment of empty capsids versus mature nucleocapsids

Liu, K. & Hu, J., Feb 1 2019, In : Future Virology. 14, 2, p. 95-105 11 p.

Research output: Contribution to journalReview article

Nucleocapsid
Capsid
Hepatitis B
Virion
RNA
2 Citations (Scopus)

The Post-GWAS Era: How to Validate the Contribution of Gene Variants in Lupus

Fike, A. J., Elcheva, I. & Rahman, Z., Jan 1 2019, In : Current rheumatology reports. 21, 1, 3.

Research output: Contribution to journalReview article

Genome-Wide Association Study
Systemic Lupus Erythematosus
Genes
Computational Biology
Autoimmune Diseases
2 Citations (Scopus)
Cottontail rabbit papillomavirus
Papillomaviridae
rabbits
Sylvilagus floridanus
Rabbits
Open Access
Central Nervous System Viral Diseases
T-Lymphocytes
Virus Diseases
Brain
T-Lymphocyte Subsets
2018
5 Citations (Scopus)

NF-κB signaling mechanisms in HTLV-1-induced adult T-cell leukemia/lymphoma

Harhaj, E. W. & Giam, C. Z., Sep 2018, In : FEBS Journal. 285, 18, p. 3324-3336 13 p.

Research output: Contribution to journalReview article

Deltaretrovirus
Adult T Cell Leukemia Lymphoma
T-cells
Viruses
Taxation
1 Citation (Scopus)

The role of pemetrexed in recurrent epithelial ovarian cancer: A scoping review

Roche, M., Parisi, L., Li, L., Knehans, A., Phaeton, R. & Kesterson, J. P., Jan 30 2018, In : Oncology Reviews. 12, 1, p. 8-13 6 p.

Research output: Contribution to journalReview article

Pemetrexed
Folic Acid Antagonists
Ovarian Neoplasms
Recurrence
Mortality
2017
59 Citations (Scopus)

Complete and incomplete hepatitis B virus particles: Formation, function, and application

Hu, J. & Liu, K., Mar 21 2017, In : Viruses. 9, 3, 56.

Research output: Contribution to journalReview article

Defective Viruses
Hepatitis B virus
Virion
Capsid
Genome
8 Citations (Scopus)

Hepatitis B virus immunopathology, model systems, and current therapies

Sandhu, P., Haque, M., Humphries-Bickley, T., Ravi, S. & Song, J., Apr 13 2017, In : Frontiers in immunology. 8, APR, 436.

Research output: Contribution to journalReview article

Hepatitis B virus
Antiviral Agents
Therapeutics
Virus Diseases
T-Lymphocytes
47 Citations (Scopus)
Melanoma
Radiotherapy
Survival
Immunotherapy
ipilimumab
22 Citations (Scopus)

Insights into the dichotomous regulation of SOD2 in cancer

Kim, Y. S., Vallur, P. G., Phaëton, R., Mythreye, K. & Hempel, N., Dec 2017, In : Antioxidants. 6, 4, 86.

Research output: Contribution to journalReview article

Tumors
Antioxidants
Oxidants
Neoplasms
Genes
11 Citations (Scopus)

Recent advances in preclinical model systems for papillomaviruses

Christensen, N. D., Budgeon, L. R., Cladel, N. M. & Hu, J., Mar 2 2017, In : Virus Research. 231, p. 108-118 11 p.

Research output: Contribution to journalReview article

Animal Models
Papillomavirus Infections
Viral Proteins
Life Cycle Stages
Research
10 Citations (Scopus)

Regnase-1, a rapid response ribonuclease regulating inflammation and stress responses

Mao, R., Yang, R., Chen, X., Harhaj, E. W., Wang, X. & Fan, Y., May 1 2017, In : Cellular and Molecular Immunology. 14, 5, p. 412-422 11 p.

Research output: Contribution to journalReview article

Ribonucleases
Inflammation
RNA-Binding Proteins
Messenger RNA
Genes
3 Citations (Scopus)

Rerouting the traffic from a virus perspective

Cruz, L. & Buchkovich, N., Jun 1 2017, In : Frontiers in Bioscience - Landmark. 22, 11, p. 1845-1866 22 p.

Research output: Contribution to journalReview article

Protein Transport
Viruses
Membranes
Viral Proteins
Virus Diseases
19 Citations (Scopus)

Spontaneous germinal centers and autoimmunity

Domeier, P. P., Schell, S. L. & Rahman, Z. S. M., Jan 2 2017, In : Autoimmunity. 50, 1, p. 4-18 15 p.

Research output: Contribution to journalReview article

Germinal Center
Autoimmunity
Autoimmune Diseases
Self Tolerance
Antibody Affinity
5 Citations (Scopus)

The use of nanoparticulates to treat breast cancer

Tang, X., Loc, W. S., Dong, C., Matters, G. L., Butler, P. J., Kester, M., Meyers, C., Jiang, Y. & Adair, J. H., Oct 2017, In : Nanomedicine. 12, 19, p. 2367-2388 22 p.

Research output: Contribution to journalReview article

Tumors
Breast Neoplasms
Oncology
Hemodynamics
Blood Circulation Time
2016
18 Citations (Scopus)

Cellular Organization of Neuroimmune Interactions in the Gastrointestinal Tract

Margolis, K. G., Gershon, M. D. & Bogunovic, M., Jul 1 2016, In : Trends in Immunology. 37, 7, p. 487-501 15 p.

Research output: Contribution to journalReview article

Neuroimmunomodulation
Enteric Nervous System
Conservation of Natural Resources
Nervous System
Vertebrates
7 Citations (Scopus)

Defining cross presentation for a wider audience

Norbury, C. C., Jun 1 2016, In : Current Opinion in Immunology. 40, p. 110-116 7 p.

Research output: Contribution to journalReview article

Cross-Priming
Peptides
Antigens
RNA
T-Lymphocytes
4 Citations (Scopus)

Development of auto antigen-specific regulatory T cells for diabetes immunotherapy

Song, J., Jan 1 2016, In : Immune Network. 16, 5, p. 281-285 5 p.

Research output: Contribution to journalReview article

Pluripotent Stem Cells
Regulatory T-Lymphocytes
Immunotherapy
Type 1 Diabetes Mellitus
Antigens
6 Citations (Scopus)

HPV disease transmission protection and control

Christensen, N. D., Sep 2016, In : Microbial Cell. 3, 9, p. 476-490 15 p.

Research output: Contribution to journalReview article

Open Access
Tissue
Viral Proteins
Pathogens
Viruses
Tropism
6 Citations (Scopus)

Innate Lymphoid Cells: A Promising New Regulator in Fibrotic Diseases

Zhang, Y., Tang, J., Tian, Z., van Velkinburgh, J. C., Song, J., Wu, Y. & Ni, B., Sep 2 2016, In : International Reviews of Immunology. 35, 5, p. 399-414 16 p.

Research output: Contribution to journalReview article

Fibrosis
Lymphocytes
Inflammation
Pulmonary Fibrosis
Adaptive Immunity
14 Citations (Scopus)

Malignant melanoma—The cradle of anti-neoplastic immunotherapy

Koller, K. M., Wang, W., Schell, T., Cozza, E. M., Kokolus, K. M., Neves, R., Mackley, H., Pameijer, C. R., Leung, A., Anderson, B., Mallon, C. A., Robertson, G. & Drabick, J., Oct 1 2016, In : Critical Reviews in Oncology/Hematology. 106, p. 25-54 30 p.

Research output: Contribution to journalReview article

Immunotherapy
Melanoma
Immune System
Therapeutics
History
6 Citations (Scopus)

Novel immunotherapies for hematological malignancies

Vasekar, M., Rizvi, S., Liu, X., Vrana, K. E. & Zheng, H., Aug 1 2016, In : Current Molecular Pharmacology. 9, 3, p. 264-271 8 p.

Research output: Contribution to journalReview article

Hematologic Neoplasms
Immunotherapy
T-Lymphocytes
Neoplasms
Antigen Presentation
10 Citations (Scopus)

Role of autophagy in the regulation of epithelial cell junctions

Nighot, P. & Ma, T., Jul 2 2016, In : Tissue Barriers. 4, 3, e1171284.

Research output: Contribution to journalReview article

Intercellular Junctions
Autophagy
Epithelial Cells
Degradation
Macromolecules
2015
18 Citations (Scopus)

Exome Sequencing of SLC30A2 Identifies Novel Loss- and Gain-of-Function Variants Associated with Breast Cell Dysfunction

Alam, S., Hennigar, S. R., Gallagher, C., Soybel, D. I. & Kelleher, S. L., Aug 21 2015, In : Journal of mammary gland biology and neoplasia. 20, 3-4, p. 159-172 14 p.

Research output: Contribution to journalReview article

Exome
Zinc
Breast
Milk
Lactation
33 Citations (Scopus)

Hepatitis B virus reverse transcriptase - Target of current antiviral therapy and future drug development

Clark, D. N. & Hu, J., Nov 1 2015, In : Antiviral Research. 123, p. 132-137 6 p.

Research output: Contribution to journalReview article

RNA-Directed DNA Polymerase
Hepatitis B virus
Antiviral Agents
Drug Therapy
Viral DNA
4 Citations (Scopus)

Lethal influenza infection: Is a macrophage to blame?

Halstead, E. S. & Chroneos, Z. C., Dec 2 2015, In : Expert Review of Anti-Infective Therapy. 13, 12, p. 1425-1428 4 p.

Research output: Contribution to journalReview article

Alveolar Macrophages
Human Influenza
Macrophages
Influenza A virus
Virus Diseases
13 Citations (Scopus)

Papillomavirus infectious pathways: A comparison of systems

Biryukov, J. & Meyers, C., Aug 4 2015, In : Viruses. 7, 8, p. 4303-4325 23 p.

Research output: Contribution to journalReview article

Virion
Life Cycle Stages
Cell Differentiation
Epithelium
Research
2 Citations (Scopus)

The importance of mouse models to define immunovirologic determinants of progressive multifocal leukoencephalopathy

Frost, E. L. & Lukacher, A. E., Jan 1 2015, In : Frontiers in immunology. 6, JAN, 00646.

Research output: Contribution to journalReview article

Progressive Multifocal Leukoencephalopathy
Demyelinating Diseases
JC Virus
Central Nervous System
Polyomavirus
9 Citations (Scopus)

Unveiling the roles of HBV polymerase for new antiviral strategies

Clark, D. N. & Hu, J., Mar 1 2015, In : Future Virology. 10, 3, p. 283-295 13 p.

Research output: Contribution to journalReview article

Antiviral Agents
RNA-Directed DNA Polymerase
RNA-Binding Proteins
DNA
RNA Stability
2014
23 Citations (Scopus)

A risk for non-sexual transmission of human papillomavirus?

Ryndock, E. J. & Meyers, C., Oct 1 2014, In : Expert Review of Anti-Infective Therapy. 12, 10, p. 1165-1170 6 p.

Research output: Contribution to journalReview article

Papillomaviridae
Vertical Infectious Disease Transmission
Fomites
Papillomavirus Infections
Disinfectants
28 Citations (Scopus)

Complement activation in malaria: Friend or foe?

Biryukov, S. & Stoute, J., Jan 1 2014, In : Trends in Molecular Medicine. 20, 5, p. 293-301 9 p.

Research output: Contribution to journalReview article

Complement Activation
Malaria
Complement Inactivating Agents
Cerebral Malaria
Complement Membrane Attack Complex
4 Citations (Scopus)

Functional implications of mitochondrial reactive oxygen species generated by oncogenic viruses

Choi, Y. B. & Harhaj, E. W., Dec 5 2014, In : Frontiers in Biology. 9, 6, p. 423-436 14 p.

Research output: Contribution to journalReview article

oncogenic viruses
Mitochondrial Degradation
Oncogenic Viruses
reactive oxygen species
Reactive Oxygen Species
15 Citations (Scopus)

Regulation of HTLV-1 tax stability, cellular trafficking and NF-κB activation by the ubiquitin-proteasome pathway

Lavorgna, A. & Harhaj, E. W., Oct 23 2014, In : Viruses. 6, 10, p. 3925-3943 19 p.

Research output: Contribution to journalReview article

Deltaretrovirus
Proteasome Endopeptidase Complex
Ubiquitin
T-Lymphocytes
Lysine
29 Citations (Scopus)

Utilizing regulatory T cells against rheumatoid arthritis

Haque, M., Fino, K., Lei, F., Xiong, X. & Song, J., Jan 1 2014, In : Frontiers in Oncology. 4 JUL, 209.

Research output: Contribution to journalReview article

Regulatory T-Lymphocytes
Rheumatoid Arthritis
Self Tolerance
Homeostasis
Immune Tolerance
2013
72 Citations (Scopus)

Bacterial Mg2+ homeostasis, transport, and virulence

Groisman, E. A., Hollands, K., Kriner, M. A., Lee, E. J., Park, S. Y. & Pontes, M. H., Nov 2013, In : Annual review of genetics. 47, p. 625-646 22 p.

Research output: Contribution to journalReview article

Virulence
Homeostasis
Bacteria
Bacterial Genomes
Divalent Cations
109 Citations (Scopus)

The expanding significance of keratin intermediate filaments in normal and diseased epithelia

Pan, X., Hobbs, R. & Coulombe, P. A., Jan 1 2013, In : Current Opinion in Cell Biology. 25, 1, p. 47-56 10 p.

Research output: Contribution to journalReview article

Intermediate Filaments
Keratins
Epithelium
Premature Aging
Intermediate Filament Proteins
2012
62 Citations (Scopus)

Cellular mechanisms of zinc dysregulation: A perspective on zinc homeostasis as an etiological factor in the development and progression of breast cancer

Alam, S. & Kelleher, S. L., Aug 2012, In : Nutrients. 4, 8, p. 875-903 29 p.

Research output: Contribution to journalReview article

breast neoplasms
Zinc
homeostasis
Homeostasis
zinc
21 Citations (Scopus)

Consortium biology in immunology: The perspective from the Immunological Genome Project

Benoist, C., Lanier, L., Merad, M., Mathis, D., Ericson, J., Painter, M., Davis, S., Laplace, C., Hyatt, G., Paik, H., Rothamel, K., Cruse, R., Doran, G., Heng, T., Asinovski, N., Ortiz-Lopes, A., Ergun, A., Gray, D., Wakamatsu, E., Hill, J. & 70 others, Mingueneau, M., Cipolletta, D., Yoshida, H., Cohen, N., Kim, E., Brennan, P., Lynch, L., Brenner, M., Costello, J., Collins, J. J., Blair, D., Dustin, M., Knell, J., Yang, E., Best, A., Shaw, L., Doedens, A., Goldrath, A., Shinton, S., Zhou, Y., Hardy, R., Jojic, V., Mostafavi, S., Koller, D., Jianu, R., Laidlaw, D., Bezman, N., Sun, J., Zhu, Y., Hendricks, D., Kamimura, Y., Min-Oo, G., Hendricks, D., Morvan, M., Kamimura, Y., Nabekura, T., Lam, V., Kim, C., Greter, M., Helft, J., Chow, A., Bogunovic, M., Mortha, A., Price, J., Hashimoto, D., Miller, J., Sathe, P., Chudnovskiy, A., Lavin, Y., Idoyaga, J., Gautier, E., Jakubzick, C., D'Angelo, J., Randolph, G., Shay, T., Regev, A., Gazit, R., Rossi, D., Kreslawsky, T., von Bohmer, H., Bellemare-Pelletier, A., Elpek, K., Spelv, L., Fletcher, A., Malhotra, D., Cremasco, V., Turley, S., Kim, F., Nageswara Rao, T. & Wagers, A., Oct 1 2012, In : Nature Reviews Immunology. 12, 10, p. 734-740 7 p.

Research output: Contribution to journalReview article

Allergy and Immunology
Genome
Research Personnel
Research
23 Citations (Scopus)

Mononuclear phagocyte diversity in the intestine

Bogunovic, M., Mortha, A., Muller, P. A. & Merad, M., Dec 1 2012, In : Immunologic Research. 54, 1-3, p. 37-49 13 p.

Research output: Contribution to journalReview article

Phagocytes
Intestines
Antigens
Intestinal Mucosa
Autoantigens
160 Citations (Scopus)

Regulation of NF-κB by deubiquitinases

Harhaj, E. W. & Dixit, V. M., Mar 1 2012, In : Immunological Reviews. 246, 1, p. 107-124 18 p.

Research output: Contribution to journalReview article

Ubiquitin
Polyubiquitin
Ubiquitin-Protein Ligases
Ubiquitination
Adaptive Immunity
95 Citations (Scopus)

Regulation of NF-κB signaling by the A20 deubiquitinase

Shembade, N. & Harhaj, E. W., Mar 1 2012, In : Cellular and Molecular Immunology. 9, 2, p. 123-130 8 p.

Research output: Contribution to journalReview article

Autoimmune Diseases
Phosphotransferases
Polyubiquitin
Inflammation
Ubiquitination
2011
18 Citations (Scopus)

Complement receptor 1 and malaria

Stoute, J., Oct 1 2011, In : Cellular Microbiology. 13, 10, p. 1441-1450 10 p.

Research output: Contribution to journalReview article

Complement C1
Complement Receptors
Malaria
Falciparum Malaria
Parasites
151 Citations (Scopus)

Deubiquitinases in the regulation of NF-κB signaling

Harhaj, E. W. & Dixit, V. M., Jan 1 2011, In : Cell Research. 21, 1, p. 22-39 18 p.

Research output: Contribution to journalReview article

NF-kappa B
Ubiquitin-Protein Ligases
Down-Regulation
Ubiquitination
Adaptive Immunity
18 Citations (Scopus)

Diverse roles of non-diverse molecules: MHC class Ib molecules in host defense and control of autoimmunity

Hofstetter, A. R., Sullivan, L. C., Lukacher, A. & Brooks, A. G., Feb 1 2011, In : Current Opinion in Immunology. 23, 1, p. 104-110 7 p.

Research output: Contribution to journalReview article

Autoimmunity
T-Lymphocytes
Histocompatibility Antigens Class I
T-Lymphocyte Subsets
Adaptive Immunity
20 Citations (Scopus)
Germinal Center
Autoimmunity
B-Lymphocytes
Antigens
Autoantibodies