Department of Pediatrics &ndash; Research Output

Allopurinol preserves cerebral energy metabolism during perinatal hypoxia-ischemia: A ³¹P NMR study in unanesthetized immature rats

Williams, G. D., Palmer, C., Heitjan, D. F. & Smith, M. B., Sep 14 1992, In : Neuroscience letters. 144, 1-2, p. 103-106 4 p.

Research output: Contribution to journal › Article

Allopurinol

Energy Metabolism

Ischemia

Brain Hypoxia-Ischemia

Phosphocreatine

5 Citations (Scopus)

Allopurinol use during maintenance therapy for acute lymphoblastic leukemia avoids mercaptopurine-related hepatotoxicity

Giamanco, N. M., Cunningham, B., Klein, L. S., Parekh, D. S., Warwick, A. B. & Lieuw, K., Jan 1 2016, In : Journal of Pediatric Hematology/Oncology. 38, 2, p. 147-151 5 p.

Research output: Contribution to journal › Article

6-Mercaptopurine

Allopurinol

Precursor Cell Lymphoblastic Leukemia-Lymphoma

Nucleotides

Therapeutics

All-terrain vehicles: Hazard in Britain

Jagger, J. & Widome, M., Dec 1 1988, In : Lancet. 2, 8624, p. 1368-1369 2 p.

Research output: Contribution to journal › Letter

Off-Road Motor Vehicles

Recreation

Wounds and Injuries

United Kingdom

1 Citation (Scopus)

A Longitudinal Healthcare Use Profile of Children with a History of Neonatal Abstinence Syndrome

Liu, G., Kong, L., Leslie, D. & Corr, T., Jan 1 2019, In : Journal of Pediatrics. 204, p. 111-117.e1

Research output: Contribution to journal › Article

Neonatal Abstinence Syndrome

Delivery of Health Care

Inpatients

Hospital Emergency Service

Hospitalization

21 Citations (Scopus)

A longitudinal study of several potential mediators of the relationship between child maltreatment and posttraumatic stress disorder symptoms

Shenk, C. E., Putnam, F. W., Rausch, J. R., Peugh, J. L. & Noll, J. G., Jan 1 2014, In : Development and Psychopathology. 26, 1, p. 81-91 11 p.

Research output: Contribution to journal › Article

Child Abuse

Post-Traumatic Stress Disorders

Longitudinal Studies

Interviews

Secondary Prevention

4 Citations (Scopus)

Alpha-thalassemia intellectual disability: Variable phenotypic expression among males with a recurrent nonsense mutation - c.109C>T (p.R37X)

Basehore, M. J., Michaelson-Cohen, R., Levy-Lahad, E., Sismani, C., Bird, L. M., Friez, M. J., Walsh, T., Abidi, F., Holloway, L., Skinner, C., Mcgee, S., Alexandrou, A., Syrrou, M., Patsalis, P. C., Raymond, G., Wang, T., Schwartz, C. E., King, M. C. & Stevenson, R. E., May 1 2015, In : Clinical Genetics. 87, 5, p. 461-466 6 p.

Research output: Contribution to journal › Article

alpha-Thalassemia

Nonsense Codon

Intellectual Disability

Phenotype

X Chromosome Inactivation

21 Citations (Scopus)

Alteration of iron regulatory proteins (IRP1 and IRP2) and ferritin in the brains of scrapie-infected mice

Kim, B. H., Jun, Y. C., Jin, J. K., Kim, J. I., Kim, N. H., Leibold, E. A., Connor, J., Choi, E. K., Carp, R. I. & Kim, Y. S., Jul 18 2007, In : Neuroscience letters. 422, 3, p. 158-163 6 p.

Research output: Contribution to journal › Article

Iron-Regulatory Proteins

Scrapie

Ferritins

Iron

Prion Diseases

16 Citations (Scopus)

Alterations in serum microRNA in humans with alcohol use disorders impact cell proliferation and cell death pathways and predict structural and functional changes in brain

Ignacio, C., Hicks, S., Burke, P., Lewis, L., Szombathyne-Meszaros, Z. & Middleton, F. A., Sep 5 2015, In : BMC Neuroscience. 16, 1, 55.

Research output: Contribution to journal › Article

MicroRNAs

Cell Death

Alcohols

Cell Proliferation

Brain

96 Citations (Scopus)

Alterations in the interaction between iron regulatory proteins and their iron responsive element in normal and Alzheimer's diseased brains.

Piñero, D. J., Hu, J. & Connor, J., Jan 1 2000, In : Cellular and molecular biology (Noisy-le-Grand, France). 46, 4, p. 761-776 16 p.

Research output: Contribution to journal › Article

Iron-Regulatory Proteins

Brain

Alzheimer Disease

Iron

Ferritins

2 Citations (Scopus)

Alterations in Transferrin and Its Receptor in the Brain of Myelin‐Deficient Rats

ROSKAMS, A. JANE. & Connor, J., Jan 1 1990, In : Annals of the New York Academy of Sciences. 605, 1, p. 391-393 3 p.

Research output: Contribution to journal › Article

Transferrin Receptors

Myelin Sheath

Brain

Rat

Alteration

14 Citations (Scopus)

Alterations in tumor necrosis factor-α expression by hepatic macrophages following acute cholestatic liver injury

Fox, E. S. & Tracy, T., Jan 1 1996, In : Shock. 5, 2, p. 112-115 4 p.

Research output: Contribution to journal › Article

Lipopolysaccharides

Peptidoglycan

Tumor Necrosis Factor-alpha

Macrophages

Liver

111 Citations (Scopus)

Altered Brain iron homeostasis and dopaminergic function in Restless Legs Syndrome (Willis-Ekbom Disease)

Earley, C. J., Connor, J., Garcia-Borreguero, D., Jenner, P., Winkelman, J., Zee, P. C. & Allen, R., Nov 1 2014, In : Sleep Medicine. 15, 11, p. 1288-1301 14 p.

Research output: Contribution to journal › Review article

Restless Legs Syndrome

Homeostasis

Iron

Brain

Animal Models

95 Citations (Scopus)

Altered cellular distribution of iron in the central nervous system of myelin deficient rats

Connor, J. & Menzies, S. L., Jan 1 1990, In : Neuroscience. 34, 1, p. 265-271 7 p.

Research output: Contribution to journal › Article

Myelin Sheath

Iron

Central Nervous System

Oligodendroglia

Microglia

2 Citations (Scopus)

Altered chemokine response in an animal model of multiple organ dysfunction syndrome induced by zymosan

Thomas, N. J., Umstead, T. M. & Phelps, D. S., Jan 1 2005, In : Journal of Pediatric Surgery. 40, 3, p. 464-469 6 p.

Research output: Contribution to journal › Article

Zymosan

Multiple Organ Failure

Chemokine CCL2

Chemokines

Animal Models

2 Citations (Scopus)

Altered CYP21 genes in HLA-haplotypes associated with congenital adrenal hyperplasia (CAH): a family study

Manfras, B. J., Swinyard, M., Rudert, W. A., Ball, E. J., Lee, P., Kühnl, P., Trucco, M. & Böhm, B. O., Aug 1 1993, In : Human Genetics. 92, 1, p. 33-39 7 p.

Research output: Contribution to journal › Article

Congenital Adrenal Hyperplasia

HLA Antigens

Haplotypes

Genes

Mutation

193 Citations (Scopus)

Altered dopaminergic profile in the putamen and substantia nigra in restless leg syndrome

Connor, J. R., Wang, X. S., Allen, R. P., Beard, J. L., Wiesinger, J. A., Felt, B. T. & Earley, C. J., Sep 2009, In : Brain. 132, 9, p. 2403-2412 10 p.

Research output: Contribution to journal › Article

Restless Legs Syndrome

Putamen

Substantia Nigra

Tyrosine 3-Monooxygenase

Iron

209 Citations (Scopus)

Altered erythrocyte endothelial adherence and membrane phospholipid asymmetry in hereditary hydrocytosis

Gallagher, P. G., Chang, S. H., Rettig, M. P., Neely, J. E., Hillery, C. A., Smith, B. D. & Low, P. S., Jun 1 2003, In : Blood. 101, 11, p. 4625-4627 3 p.

Research output: Contribution to journal › Article

Phosphatidylserines

Phospholipids

Erythrocytes

Thrombospondins

Membranes

5 Citations (Scopus)

Altered eyeblink reflex conditioning in restless legs syndrome patients

McEchron, M. D., Alexander, D. N., Smith, M. E., Hoffman, D. L., Podskalny, G. D. & Connor, J., Mar 1 2010, In : Sleep Medicine. 11, 3, p. 314-319 6 p.

Research output: Contribution to journal › Article

Restless Legs Syndrome

Reflex

Conditioning (Psychology)

Lower Extremity

Leg

38 Citations (Scopus)

Altered growth and protein turnover in rats fed sodium-deficient diets

Wassner, S., 1989, In : Pediatric Research. 26, 6, p. 608-613 6 p.

Research output: Contribution to journal › Article

Muscle Proteins

Sodium

Proteolysis

Diet

Growth

34 Citations (Scopus)

Altered heart rhythm dynamics in very low birth weight infants with impending intraventricular hemorrhage

Tuzcu, V., Nas, S., Ulusar, U., Ugur, A. & Kaiser, J. R., Mar 1 2009, In : Pediatrics. 123, 3, p. 810-815 6 p.

Research output: Contribution to journal › Article

Very Low Birth Weight Infant

Hemorrhage

Fractals

Autonomic Nervous System

Birth Weight

29 Citations (Scopus)

Altered iron metabolism in lymphocytes from subjects with restless legs syndrome

Earley, C. J., Ponnuru, P., Wang, X., Patton, S., Connor, J., Beard, J. L., Taub, D. D. & Allen, R. P., Jun 1 2008, In : Sleep. 31, 6, p. 847-852 6 p.

Research output: Contribution to journal › Article

Restless Legs Syndrome

Iron

Lymphocytes

Transferrin Receptors

Proteins

100 Citations (Scopus)

Altered monamine metabolism in caudate-putamen of iron-deficient rats

Beard, J. L., Chen, Q., Connor, J. & Jones, B. C., Jan 1 1994, In : Pharmacology, Biochemistry and Behavior. 48, 3, p. 621-624 4 p.

Research output: Contribution to journal › Article

Putamen

Metabolism

Rats

Iron

Microdialysis

11 Citations (Scopus)

Altered Patterns of Early Metabolic Decompensation in Type 1 Diabetes during Treatment with a SGLT2 Inhibitor: An Insulin Pump Suspension Study

Patel, N., Van Name, M. A., Cengiz, E., Carria, L. R., Weinzimer, S. A., Tamborlane, W. V. & Sherr, J. L., Nov 1 2017, In : Diabetes Technology and Therapeutics. 19, 11, p. 618-622 5 p.

Research output: Contribution to journal › Article

Type 1 Diabetes Mellitus

Suspensions

Insulin

Sodium-Glucose Transport Proteins

Glucose

77 Citations (Scopus)

Altered serial position learning after frontal lobe lesion

Eslinger, P. & Grattan, L. M., Jan 1 1994, In : Neuropsychologia. 32, 6, p. 729-739 11 p.

Research output: Contribution to journal › Article

Serial Learning

Frontal Lobe

Learning

Verbal Learning

19 Citations (Scopus)

Altered sphingolipid metabolism in patients with metastatic pancreatic cancer

Jiang, Y., DiVittore, N. A., Young, M. M., Jia, Z., Xie, K., Ritty, T. M., Kester, M. & Fox, T. E., Sep 2013, In : Biomolecules. 3, 3, p. 435-448 14 p.

Research output: Contribution to journal › Article

Open Access

Sphingolipids

Pancreatic Neoplasms

Metabolism

Chemokine CXCL10

Plasmas

32 Citations (Scopus)

Altered ventricular mechanics in cardiac allografts: A tissue doppler study in 30 children without prior rejection events

Pauliks, L., Pietra, B. A., Kirby, S., Logan, L., Degroff, C. G., Boucek, M. M. & Valdes-Cruz, L. M., Nov 1 2005, In : Journal of Heart and Lung Transplantation. 24, 11, p. 1804-1813 10 p.

Research output: Contribution to journal › Article

Mechanics

Allografts

Heart Ventricles

Heart Transplantation

Transplantation

15 Citations (Scopus)

Alternative diagnoses at paediatric appendicitis MRI

Moore, M., Kulaylat, A. N., Brian, J., Khaku, A., Hulse, M., Engbrecht, B., Methratta, S. & Boal, D. K. B., Jan 1 2015, In : Clinical Radiology. 70, 8, p. 881-889 9 p.

Research output: Contribution to journal › Review article

Appendicitis

Pediatrics

Lymphadenitis

Abdominal Pain

Pathology

15 Citations (Scopus)

Alternative modified infant-feeding practices to prevent postnatal transmission of human immunodeficiency virus type 1 through breast milk: Past, present, and future

Hartmann, S. U., Berlin, C. & Howett, M. M., Feb 1 2006, In : Journal of Human Lactation. 22, 1, p. 75-88 14 p.

Research output: Contribution to journal › Review article

Human Milk

HIV-1

Mothers

Breast Feeding

Milk

84 Citations (Scopus)

Alternative routes of drug administration - Advantages and disadvantages (subject review)

Berlin, J., May-McCarver, D. G., Notterman, D. A., Ward, R. M., Weismann, D. N., Wilson, G. S., Wilson, J. T., Bennett, D. R., Hoskins, I. A., Kaufman, P., Mithani, S., Mulinare, J., Troendle, G., March, J., Yaffe, S. J., Szefler, S. J. & Cote, C. J., Jul 1 1997, In : Pediatrics. 100, 1, p. 143-152 10 p.

Research output: Contribution to journal › Review article

Drug Administration Routes

Mucosal Administration

Drug Compounding

Patient Compliance

Drug-Related Side Effects and Adverse Reactions

10 Citations (Scopus)

Alternative routes of drug administration - Advantages and disadvantages (Subject review) [3] (multiple letters)

Zempsky, W. T., Cote, C. J. & Berlin, J., May 5 1998, In : Pediatrics. 101, 4 I, p. 730-731 2 p.

Research output: Contribution to journal › Letter

Combined Anesthetics

Drug Administration Routes

Tetracaine

Iontophoresis

Mouth Mucosa

175 Citations (Scopus)

Aluminum access to the brain: A role for transferrin and its receptor

Roskams, A. J. & Connor, J. R., Nov 1990, In : Proceedings of the National Academy of Sciences of the United States of America. 87, 22, p. 9024-9027 4 p.

Research output: Contribution to journal › Article

Transferrin Receptors

Aluminum

Brain

Central Nervous System

Alzheimer Disease

52 Citations (Scopus)

Alveolar-arterial oxygen gradient as a predictor of outcome in patients with nonneonatal pediatric respiratory failure

Tamburro, R., Bugnitz, M. C. & Stidham, G. L., Jan 1 1991, In : The Journal of pediatrics. 119, 6, p. 935-938 4 p.

Research output: Contribution to journal › Article

Pulmonary Gas Exchange

Preschool Children

Survival Analysis

Respiratory Insufficiency

Retrospective Studies

20 Citations (Scopus)

Alveolar Dead Space Fraction Discriminates Mortality in Pediatric Acute Respiratory Distress Syndrome

Yehya, N., Bhalla, A. K., Thomas, N. J. & Khemani, R. G., Feb 1 2016, In : Pediatric Critical Care Medicine. 17, 2, p. 101-109 9 p.

Research output: Contribution to journal › Article

Adult Respiratory Distress Syndrome

Pediatrics

Mortality

Acute Lung Injury

Survivors

17 Citations (Scopus)

Alzheimer's dementia: Performance on parallel forms of the dementia assessment battery

Teng, E. L., Wimer, C., Roberts, E., Damasio, A. R., Eslinger, P., Folstein, M. F., Tune, L. E., Whitehouse, P. J., Bardolph, E. L., Chui, H. C. & Henderson, V. W., Jan 1 1989, In : Journal of Clinical and Experimental Neuropsychology. 11, 6, p. 899-912 14 p.

Research output: Contribution to journal › Article

1 Citation (Scopus)

A manikin-based evaluation of a teaching modality for ultrasound-guided infraclavicular longitudinal in-plane axillary vein cannulation in comparison with ultrasound-guided internal jugular vein cannulation: A pilot study

Adhikary, S., McQuillan, P., Fortunato, M., Owen, D., Liu, W. M. & Thiruvenkatarajan, V., Jul 1 2017, In : Journal of Anaesthesiology Clinical Pharmacology. 33, 3, p. 337-341 5 p.

Research output: Contribution to journal › Article

Axillary Vein

Manikins

Jugular Veins

Catheterization

Teaching

19 Citations (Scopus)

Amantadine for adynamic speech: Possible benefit for aphasia?

Barrett, A. M. & Eslinger, P., Sep 1 2007, In : American Journal of Physical Medicine and Rehabilitation. 86, 8, p. 605-612 8 p.

Research output: Contribution to journal › Article

Amantadine

Aphasia

Broca Aphasia

Word Association Tests

Stroke

4 Citations (Scopus)

Amantadine penetration into cerebrospinal fluid of a child with influenza A encephalitis

Geskey, J. M. & Thomas, N. J., Mar 1 2004, In : Pediatric Infectious Disease Journal. 23, 3, p. 270-272 3 p.

Research output: Contribution to journal › Article

Amantadine

Encephalitis

Human Influenza

Cerebrospinal Fluid

Virus Diseases

25 Citations (Scopus)

A matched pairs analysis of venoarterial and venovenous extracorporeal life support in neonatal respiratory failure

Gauger, P. G., Hirschl, R. B., Delosh, T. N., Dechert, R. E., Tracy, T. & Bartlett, R. H., Jan 1 1995, In : ASAIO Journal. 41, 3

Research output: Contribution to journal › Article

Matched-Pair Analysis

Extracorporeal Membrane Oxygenation

Hemodynamics

Respiratory Insufficiency

Oxygenation

2 Citations (Scopus)

Ambiguous genitalia

Witchel, S. F. & Lee, P. A., Mar 1 2014, Pediatric Endocrinology: Fourth Edition. Elsevier Inc., p. 107-156.e1

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Disorders of Sex Development

7 Citations (Scopus)

Ambiguous Genitalia

Witchel, S. F. & Lee, P., Dec 1 2008, Pediatric Endocrinology. Elsevier Inc., p. 127-164 38 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

170 Citations (Scopus)

American Academy of Allergy, Asthma & Immunology Work Group Report: Exercise-induced asthma

Weiler, J. M., Bonini, S., Coifman, R., Craig, T., Delgado, L., Capão-Filipe, M., Passali, D., Randolph, C. & Storms, W., Jun 1 2007, In : Journal of Allergy and Clinical Immunology. 119, 6, p. 1349-1358 10 p.

Research output: Contribution to journal › Article

Exercise-Induced Asthma

Medical Societies

Anaphylaxis

Allergy and Immunology

Athletes

American Pediatric Surgical Association Trauma Committee Position Statement on the Use of All-Terrain Vehicles by Children and Youth, 2018

Engbrecht, B. & Baertschiger, R. M., Jul 1 2018, In : Journal of pediatric surgery. 53, 7, p. 1444-1445 2 p.

Research output: Contribution to journal › Letter

Off-Road Motor Vehicles

Pediatrics

Wounds and Injuries

3 Citations (Scopus)

American Society of Clinical Oncology Summit on Addressing Obesity Through Multidisciplinary Provider Collaboration: Key Findings and Recommendations for Action

Ligibel, J. A., Alfano, C. M., Hershman, D. L., Merrill, J. K., Basen-Engquist, K., Bloomgarden, Z. T., Demark-Wahnefried, W., Dixon, S., Hassink, S. G., Jakicic, J. M., Morton, J. M., Okwuosa, T. M., Powell-Wiley, T. M., Rothberg, A. E., Stephens, M., Streett, S. E., Wild, R. A., Westman, E. A., Williams, R., Wollins, D. S. & 1 others, Hudis, C. A., Nov 1 2017, In : Obesity. 25, p. S34-S39

Research output: Contribution to journal › Article

Obesity

Education

Medical Oncology

Research

Health Personnel

1 Citation (Scopus)

A method to determine the likelihood of transition to puberty in a heterogeneous prepubertal age group

Frane, J., Bright, G. M. & Lee, P. A., Oct 1 2012, In : Journal of Pediatric Endocrinology and Metabolism. 25, 9-10, p. 843-846 4 p.

Research output: Contribution to journal › Article

Puberty

Age Groups

Growth

306 Citations (Scopus)

A microfluidic device for continuous, real time blood plasma separation

Yang, S., Undar, A. & Zahn, J. D., Jan 1 2006, In : Lab on a Chip. 6, 7, p. 871-880 10 p.

Research output: Contribution to journal › Article

Lab-On-A-Chip Devices

Microfluidics

Blood

Plasmas

Hematocrit

11 Citations (Scopus)

AMID mediates adenosine-induced caspase-independent HuH-7 cell apoptosis

Yang, D., Yaguchi, T., Nagata, T., Gotoh, A., Dovat, S., Song, C. & Nishizaki, T., Jan 1 2011, In : Cellular Physiology and Biochemistry. 27, 1, p. 37-44 8 p.

Research output: Contribution to journal › Article

Caspases

Adenosine

Mitochondria

Apoptosis

Apoptosis Inducing Factor

5 Citations (Scopus)

A minimal cytoplasmic subdomain of the erythropoietin receptor mediates p70 S6 kinase phosphorylation

Zhang, M. Y., Barber, D. L., Alessi, D. R., Bell, L. L., Stine, C., Nguyen, M. H. H., Beattie, B. K., Cheung, J. Y. & Miller, B., Apr 25 2001, In : Experimental Hematology. 29, 4, p. 432-440 9 p.

Research output: Contribution to journal › Article

Erythropoietin Receptors

70-kDa Ribosomal Protein S6 Kinases

Erythropoietin

Phosphorylation

Phosphatidylinositols

339 Citations (Scopus)

Amnesia Following Basal Forebrain Lesions

Damasio, A. R., Graff-Radford, N. R., Eslinger, P., Damasio, H. & Kassell, N., Jan 1 1985, In : Archives of Neurology. 42, 3, p. 263-271 9 p.

Research output: Contribution to journal › Article

Amnesia

Substantia Innominata

Korsakoff Syndrome

Dichlororibofuranosylbenzimidazole

Septal Nuclei

44 Citations (Scopus)

Amniotic Fluid Steroid Levels: Fetuses With Adrenal Hyperplasia, 46,XXY Fetuses, and Normal Fetuses

Carson, D. J., Okuno, A., Lee, P. & Migeon, C. J., Jan 1 1982, In : American Journal of Diseases of Children. 136, 3, p. 218-222 5 p.

Research output: Contribution to journal › Article

Amniotic Fluid

Hyperplasia

Fetus

Steroids

Dehydroepiandrosterone Sulfate

4 Citations (Scopus)

A model-based approach to assess the exposure-response relationship of Lorenzo's oil in adrenoleukodystrophy

Ahmed, M. A., Kartha, R. V., Brundage, R. C., Cloyd, J., Basu, C., Carlin, B. P., Jones, R. O., Moser, A. B., Fatemi, A. & Raymond, G. V., Jun 1 2016, In : British Journal of Clinical Pharmacology. 81, 6, p. 1058-1066 9 p.

Research output: Contribution to journal › Article

Adrenoleukodystrophy

Erucic Acids

Fatty Acids

Peroxisomal Disorders

Brain