Organization profile

Organization profile

The Department of Pharmacology at Penn State College of Medicine is dedicated to teaching and research in the biomedical sciences. Its missions are to provide high-quality training of the next generation of scientists and physicians and to develop new diagnostic tests, medicines and delivery systems.

At its home in Hershey, Pa., the Department of Pharmacology occupies 20,000 square feet of state-of-the-art laboratory space in the Hershey Center for Applied Research, Penn State Cancer Institute and Penn State Institute for Personalized Medicine.

Research ranges from cell and molecular studies of cancer, to biochemical/pharmacological investigation of nervous system function, to whole-animal studies of drug development.

As educational leaders in their fields, departmental faculty are involved in medical, graduate and allied health instruction and training.

Fingerprint Dive into the research topics where Department of Pharmacology is active. These topic labels come from the works of this organization's members. Together they form a unique fingerprint.

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    Photo of Alfredo Bellon

    Alfredo Bellon, MD, PhD

    Person: Academic

    Photo of Anthony Bonavia
    Photo of Matthew Coates

    Matthew Coates, MD, PhD

    Person: Academic


    Research Output

    An Efficient Synthesis of Dibenzo[a,l]tetracene and Dibenzo[a,j]tetracene and Their Identification in a Coal Tar Extract

    Ramisetti, S. R., Oña-Ruales, J. O., Wise, S. A., Amin, S. & Sharma, A. K., Jan 1 2020, In : Polycyclic Aromatic Compounds. 40, 1, p. 88-98 11 p.

    Research output: Contribution to journalArticle

  • Cellular signaling and epigenetic regulation of gene expression in leukemia

    Gowda, C., Song, C., Ding, Y., Iyer, S., Dhanyamraju, P. K., McGrath, M., Bamme, Y., Soliman, M., Kane, S., Payne, J. L. & Dovat, S., Jan 2020, In : Advances in Biological Regulation. 75, 100665.

    Research output: Contribution to journalReview article

    Open Access
  • c-Jun N terminal kinase signaling pathways mediate cannabinoid tolerance in an agonist-specific manner

    Henderson-Redmond, A. N., Nealon, C. M., Davis, B. J., Yuill, M. B., Sepulveda, D. E., Blanton, H. L., Piscura, M. K., Zee, M. L., Haskins, C. P., Marcus, D. J., Mackie, K., Guindon, J. & Morgan, D. J., Mar 1 2020, In : Neuropharmacology. 164, 107847.

    Research output: Contribution to journalArticle

  • Context-dependent activation of SIRT3 is necessary for anchorage-independent survival and metastasis of ovarian cancer cells

    Kim, Y. S., Gupta Vallur, P., Jones, V. M., Worley, B. L., Shimko, S., Shin, D. H., Crawford, L. T. C., Chen, C. W., Aird, K. M., Abraham, T., Shepherd, T. G., Warrick, J. I., Lee, N. Y., Phaeton, R., Mythreye, K. & Hempel, N., Feb 20 2020, In : Oncogene. 39, 8, p. 1619-1633 15 p.

    Research output: Contribution to journalArticle

  • Current Basal and Squamous Cell Skin Cancer Management

    Massand, S. & Neves, R. I., Jan 1 2020, (Accepted/In press) In : Plastic and reconstructive surgery. p. 520E-521E

    Research output: Contribution to journalLetter

    Design, synthesis characterization and biological evaluation of novel multi-isoform ALDH inhibitors as potential anticancer agents

    Dinavahi, S. S., Gowda, R., Bazewicz, C. G., Battu, M. B., Lin, J. M., Chitren, R. J., Pandey, M. K., Amin, S., Robertson, G. P. & Gowda, K., Feb 1 2020, In : European Journal of Medicinal Chemistry. 187, 111962.

    Research output: Contribution to journalArticle

  • Development and Therapeutic Potential of Selenazo Compounds

    Ruberte, A. C., Sanmartin, C., Aydillo, C., Sharma, A. K. & Plano, D., Feb 27 2020, In : Journal of Medicinal Chemistry. 63, 4, p. 1473-1489 17 p.

    Research output: Contribution to journalArticle

  • 1 Scopus citations

    Development of a Novel Multi-Isoform ALDH Inhibitor Effective as an Antimelanoma Agent

    Dinavahi, S. S., Gowda, R., Gowda, K., Bazewicz, C. G., Chirasani, V. R., Battu, M. B., Berg, A., Dokholyan, N. V., Amin, S. & Robertson, G. P., Feb 1 2020, In : Molecular cancer therapeutics. 19, 2, p. 447-459 13 p.

    Research output: Contribution to journalArticle

  • Dopamine beta-hydroxylase and its genetic variants in human health and disease

    Gonzalez-Lopez, E. & Vrana, K. E., Jan 1 2020, In : Journal of neurochemistry. 152, 2, p. 157-181 25 p.

    Research output: Contribution to journalReview article

    Open Access
  • 1 Scopus citations

    Gastrointestinal hypoalgesia in inflammatory bowel disease

    Coates, M. D., Soriano, C., Dalessio, S., Stuart, A., Walter, V., Koltun, W., Bernasko, N., Tinsley, A., Clarke, K. & Williams, E. D., Jan 1 2020, In : Annals of Gastroenterology. 33, 1, p. 45-52 8 p.

    Research output: Contribution to journalArticle

    Open Access
  • Projects

  • Activities

    • 3 Oral presentation

    From Morphology to Math: Using whole zebrafish to create the engineering and computational infrastructure for Microanatomic Phenomics

    Keith Cheng (Speaker), Y Ding (Speaker), SR Katz (Speaker), AY Lin (Speaker), D van Rossum (Speaker), D Vanselow (Speaker)
    Sep 27 2017

    Activity: Talk typesOral presentation

    Morphometric phenomics and Cross-Atlas Registration of Virtual 3D soft tissue microCT images of Zebrafish

    Keith Cheng (Speaker), Y Ding (Speaker), AY Lin (Speaker), M Yakovlev (Speaker), D Vanselow (Speaker), X Xin (Speaker), S Katz (Speaker), D Vanselow (Speaker), PJ La Riviere (Speaker)
    Jul 5 2017

    Activity: Talk typesOral presentation


    Fellow (Elected)

    Kent Vrana (Recipient), 2016

    Prize: Honorary award

    Junior Faculty Research Scholar Award

    Ryan Hobbs (Recipient), Nicholas Graziane (Recipient), Hyun Jin Kwun (Recipient) & Jonathan Stine (Recipient), 2018


    Outstanding Collaborative Research Award

    Karam El-Bayoumy (Recipient), Andrea Manni (Recipient), John Richie (Recipient), Jiangang (Jason) Liao (Recipient), John Patrick Vanden Heuvel (Recipient), Laurence Demers (Recipient), James Dillard (Recipient) & Connie Jo Rogers (Recipient), 2016