Projects 1975 2024

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Alcoholism
Blood Proteins
Biomarkers
Drinking Behavior
Finland
Melanoma
Therapeutics
Carcinogenesis
Quality of Life
Isothiocyanates
Herbal Medicine
Chemoprevention
Prostate
Prostatic Neoplasms
Neoplasm Metastasis

A novel compound for colorectal cancer prevention

Sharma, A. & Sharma, A. K.

National Institutes of Health

7/11/143/31/17

Project: Research project

Aspirin
Colorectal Neoplasms
Hydrogen Cyanide
Inbred F344 Rats
Carcinogenesis

BIOMEDICAL RESEARCH SUPPORT

Vrana, K., Sheil, J., Johnson, M., Stenberg, R., Charon, N., Shiel, J., Shiemke, A., Jackson, T., Reasor, M., Omar, R., Charon, H., Mawhinney, M., Polak, M., Hedge, G., Landreth, K., Murgo, A., Dey, R., Nyles, C., Faynor, S., Brown, P., Evans, M., Birkle, D., Worley, J., Sayed, A., Kletzien, R., Kirk, R., Butcher, F., Hedge, G. & Hill, R.

National Institutes of Health

4/1/793/31/94

Project: Research project

Calcium Signaling &Prefrontal Deficits in Schizophrenia

Levenson, R., Arnsten, A. F. T., Bradberry, C., Lidow, M., Krystal, J., Selemon, L., Mathalon, D., Bergson, C., Mc Cormick, D., Gao, W., Friedman, H., Rakic, P. & McCormick, D.

National Institutes of Health

12/12/0311/30/09

Project: Research project

Dopamine
Schizophrenia
Dopamine Receptors
Calcium
Prefrontal Cortex

CANCER CENTER SUPPORT GRANT

Amin, S., Haley, N. J., Rivenson, A., Ronai, Z., Wynder, E., Brunnemann, K., Ng, S., Rozycki, L., Hard, G., Sweeney, N., Nixon, D., Jeffrey, A., Iatropoulos, M., Thompson, S., Prokopczyk, B., Richie, J. & Albino, A.

National Institutes of Health

8/1/7911/30/06

Project: Research project

Synthetic Chemistry Techniques
Photolysis
Neoplasms
Environmental Carcinogens
Assays
Genes
Adenosine Triphosphatases
Protein Isoforms
Complementary DNA
Ouabain
Infection
Anti-Bacterial Agents
Therapeutics
Bacteria
bolaamphiphile
Celecoxib
Cyclooxygenase 2 Inhibitors
Chemoprevention
Colonic Neoplasms
Inbred F344 Rats
Melanoma
Apoptosis
plumbagin
Sunscreening Agents
Skin Neoplasms

CHILD DEVELOPMENT AND MENTAL RETARDATION

Mailman, R., Hershey, H. G., Fordham, C., Helms, R. W., Suzuki, K., Burchinal, M., Piven, J., Reznick, J., Hatton, D., Boccia, M., Bailey, D., Skinner, D., Warren, S., Seltzer, M. M. & Belger, A.

National Institutes of Health

9/1/779/23/13

Project: Research project

Computer hardware
Information technology
Intranets
Computer programming
Application programs
Glioma
Glioblastoma
Biological Products
Brain Neoplasms
Stilbenes
Lung Neoplasms
Aspirin
Hydrogen Cyanide
Anti-Inflammatory Agents
Pharmaceutical Preparations

Development of a Novel Class for Opioid Drugs

Dokholyan, N. & Diatchenko, L.

National Institutes of Health

4/1/129/30/14

Project: Research project

Opioid Analgesics
mu Opioid Receptor
Protein Isoforms
Analgesics
Pharmaceutical Preparations
oxaliplatin
Platinum
Cisplatin
DNA-Directed DNA Polymerase
Nuclear magnetic resonance
Farnesyltranstransferase
Feasibility Studies
Osteoporosis
Diphosphonates
Bone Resorption
Self Administration
Genomics
Cocaine
Cocaine-Related Disorders
Gene Expression

Functional Selectivity: A Novel approach for CNS Drug Discovery

Mailman, R., Roth, B., Caron, M. G., Caron, M. G., Wetsel, W. & Jian, J.

National Institutes of Health

9/28/074/30/18

Project: Research project

Ligands
Dopamine D2 Receptors
Antipsychotic Agents
Schizophrenia
Signal Transduction
Heroin Dependence
mu Opioid Receptor
Opioid Analgesics
Heroin
Prefrontal Cortex

IMMUNE AND BRAIN STUDIES

Mailman, R. & Allen, A.

National Institutes of Health

12/8/8912/27/94

Project: Research project

Brain
Parturition
Haplorhini
Rodentia
Lithium
Epitopes
Carbohydrates
HIV
Viruses
Glycosylation
Farnesyltranstransferase
Prostatic Neoplasms
zoledronic acid
Bone and Bones
Heterografts
Chemoprevention
Colonic Neoplasms
Phosphatidylinositol 3-Kinases
Neoplasms
Selenium
Carcinogenesis
Pentanones
Cytochrome P-450 Enzyme System
Lung
Microsomes

ISC-4 as a Novel Lung Cancer Chemopreventive Agent

Sharma, A. & Sharma, A. K.

National Institutes of Health

9/30/098/31/11

Project: Research project

Lung Neoplasms
Selenium
Neoplasms
Enzymes
Isothiocyanates
Epidermal Growth Factor Receptor
Ligands
Ubiquitination
Phosphorylation
Endosomes
Chemoprevention
Melanoma
Small Interfering RNA
Skin
Technology
Chemoprevention
Selenium
Prostatic Neoplasms
Selenomethionine
Prostate

MHCRC--PSYCHOENDOCRINOLOGY

Mailman, R., Stern, R., Garbutt, J., Mason, G., Golden, R., Carson, S., Prange, A. J., Richardson, W., Lieberman, J., Charles, H., Muller, K., Perkins, D. O. & Silva, S.

National Institutes of Health

7/1/795/31/02

Project: Research project

High performance liquid chromatography
Assays
Molecules
Testing
Xenobiotics
Oxidation-Reduction
Reactive Oxygen Species
Neoplasm Metastasis
Neoplasms
Urinary Bladder Neoplasms
Epitopes
Photoreceptor Cells
Isoenzymes
Hydra
Genes
Adenosine Triphosphatases
Ouabain
Messenger RNA
Protein Isoforms
Cardiac Glycosides
Tyrosine 3-Monooxygenase
Biogenic Amines
Enzymes
Tryptophan Hydroxylase
biogenic amines
Olfactory Bulb
Smell
Aptitude
Central Nervous System
Synaptic Vesicles
Dopamine D1 Receptors
Hemagglutinins
Arrestins
Arrestin
GTP-Binding Proteins

MULTI-DISCIPLINARY TRAINING IN THE BIOLOGY OF ALCOHOLISM

Vrana, K., Samson, H., Grant, K., McCool, B. & Friedman, D.

National Institutes of Health

7/1/946/30/19

Project: Research project

Alcoholism
Alcohols
Neurosciences
Biochemistry
Students

Mu Opioid Receptor in Addiction

Levenson, R., Ferraro, T. & Berrettini, W.

National Institutes of Health

9/30/085/31/13

Project: Research project

Receptor-Interacting Protein Serine-Threonine Kinases
mu Opioid Receptor
Opioid Analgesics
Proteins
Substance-Related Disorders

NEUROBIOLOGY OF ENVIRONMENTAL POLLUTANTS

Mailman, R., Krigman, M., Goodrum, J., Morell, P., Suzuki, K., Bouldin, T. & Krigman, M.

National Institutes of Health

5/1/759/19/98

Project: Research project

Environmental Pollutants
Neurobiology
Nervous System
Metals
Organotin Compounds
Neuropharmacology
Phenothiazines
Pharmaceutical Preparations
Thioridazine
Trifluoperazine
Brain
Pharmaceutical Preparations
Functional groups
Bearings (structural)
Poisons
Ligands
Adenylyl Cyclases
Dopamine D1 Receptors
Pharmaceutical Preparations
Drug Design
Substance-Related Disorders
Recurrence
kappa Opioid Receptor
Narcotic Antagonists
Opioid Receptors
Ants
Bone Diseases
Prostatic Neoplasms
Breast Neoplasms
Morbidity
Selenium
Prostate
Carcinogenesis
Methionine
Prostatic Neoplasms

Prevention of PTEN deletion driven prostate cancer by selenium

Lu, J., Lu, J., Deng, Y. & Deng, Y.

National Institutes of Health

12/15/1011/30/13

Project: Research project

Selenium
Prostatic Neoplasms
Selenomethionine
Prostate
Vitamin E
Rubiaceae
Chemoprevention
Prostatic Neoplasms
Glucose
Apoptosis
Amyotrophic Lateral Sclerosis
Mutation
Proteins
Neurodegenerative Diseases
Poisons
Superoxide Dismutase
Cell Movement
Reactive Oxygen Species
Neoplasms
Focal Adhesion Protein-Tyrosine Kinases